-- dump date   	20140619_044156
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
699034000001	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
699034000002	Domain of unknown function (DUF4355); Region: DUF4355; pfam14265
699034000003	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
699034000004	Head-Tail Connector Proteins gp6 and gp15, and similar proteins; Region: gp6_gp15_like; cl12049
699034000005	Bacteriophage HK97-gp10, putative tail-component; Region: HK97-gp10_like; pfam04883
699034000006	Phage tail sheath protein; Region: Phage_sheath_1; pfam04984
699034000007	Protein of unknown function (DUF2001); Region: DUF2001; pfam09393
699034000008	Phage XkdN-like protein; Region: XkdN; pfam08890
699034000009	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cl19050
699034000010	Phage-related protein [Function unknown]; Region: COG5412
699034000011	Glycine zipper 2TM domain; Region: Rick_17kDa_Anti; cl10470
699034000012	Domain of unknown function (DUF4352); Region: DUF4352; pfam11611
699034000013	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
699034000014	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
699034000015	NlpC/P60 family; Region: NLPC_P60; pfam00877
699034000016	Protein of unknown function (DUF2577); Region: DUF2577; pfam10844
699034000017	Protein of unknown function (DUF2634); Region: DUF2634; pfam10934
699034000018	Uncharacterized homolog of phage Mu protein gp47 [Function unknown]; Region: XkdT; COG3299
699034000019	Uncharacterized protein conserved in bacteria (DUF2313); Region: DUF2313; pfam10076
699034000020	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
699034000021	Viral coat protein; Region: Flexi_CP; pfam00286
699034000022	Inner membrane protein CreD; Region: CreD; cl01844
699034000023	Holin family; Region: Phage_holin_4; cl01989
699034000024	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
699034000025	active site
699034000026	metal binding site [ion binding]; metal-binding site
699034000027	potential frameshift: common BLAST hit: gi|299769744|ref|YP_003731770.1| phage DNA methylase
699034000028	Penicillinase repressor; Region: Penicillinase_R; cl17580
699034000029	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
699034000030	Mg binding site [ion binding]; other site
699034000031	nucleotide binding site [chemical binding]; other site
699034000032	putative protofilament interface [polypeptide binding]; other site
699034000033	GIY-YIG catalytic domain; Region: GIY-YIG; pfam01541
699034000034	GIY-YIG motif/motif A; other site
699034000035	active site
699034000036	catalytic site [active]
699034000037	metal binding site [ion binding]; metal-binding site
699034000038	GIY-YIG nuclease domain superfamily; Region: GIY-YIG_SF; cl15257
699034000039	GIY-YIG motif/motif A; other site
699034000040	active site
699034000041	catalytic site [active]
699034000042	metal binding site [ion binding]; metal-binding site
699034000043	Initiator Replication protein; Region: Rep_3; pfam01051
699034000044	HTH domain; Region: HTH_11; cl17392
699034000045	Penicillinase repressor; Region: Penicillinase_R; pfam03965
699034000046	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
699034000047	Double zinc ribbon; Region: DZR; pfam12773
699034000048	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034000049	non-specific DNA binding site [nucleotide binding]; other site
699034000050	salt bridge; other site
699034000051	sequence-specific DNA binding site [nucleotide binding]; other site
699034000052	Helix-turn-helix domain; Region: HTH_36; pfam13730
699034000053	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
699034000054	phage replicative helicase, DnaB family, HK022 subfamily; Region: phage_DnaB; TIGR03600
699034000055	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
699034000056	Walker A motif; other site
699034000057	ATP binding site [chemical binding]; other site
699034000058	Walker B motif; other site
699034000059	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
699034000060	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
699034000061	dimer interface [polypeptide binding]; other site
699034000062	ssDNA binding site [nucleotide binding]; other site
699034000063	tetramer (dimer of dimers) interface [polypeptide binding]; other site
699034000064	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
699034000065	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
699034000066	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
699034000067	putative DNA binding site [nucleotide binding]; other site
699034000068	putative Zn2+ binding site [ion binding]; other site
699034000069	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
699034000070	active site
699034000071	DNA binding site [nucleotide binding]
699034000072	Int/Topo IB signature motif; other site
699034000073	Terminase small subunit; Region: Terminase_2; cl01513
699034000074	Helix-turn-helix domain; Region: HTH_28; pfam13518
699034000075	Phage portal protein, SPP1 Gp6-like; Region: Phage_prot_Gp6; cl19531
699034000076	Peptidyl-tRNA hydrolase, type 2 (PTH2)_like . Peptidyl-tRNA hydrolase activity releases tRNA from the premature translation termination product peptidyl-tRNA. Two structurally different enzymes have been reported to encode such activity, Pth present in...; Region: PTH2_family; cd02407
699034000077	dimer interface [polypeptide binding]; other site
699034000078	putative active site [active]
699034000079	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
699034000080	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
699034000081	NlpC/P60 family; Region: NLPC_P60; pfam00877
699034000082	Uncharacterized conserved protein (DUF2196); Region: DUF2196; cl02044
699034000083	Toxic anion resistance protein (TelA); Region: TelA; pfam05816
699034000084	anaerobic ribonucleoside-triphosphate reductase activating protein; Region: NrdG; TIGR02491
699034000085	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
699034000086	FeS/SAM binding site; other site
699034000087	Plasmid encoded RepA protein; Region: RepA_C; pfam04796
699034000088	Topoisomerase II-associated protein PAT1; Region: PAT1; pfam09770
699034000089	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
699034000090	C-type lectin (CTL)/C-type lectin-like (CTLD) domain; Region: CLECT; cl02432
699034000091	ligand binding surface [chemical binding]; other site
699034000092	A bacterial subgroup of the C-type lectin-like (CTLD) domain; a subgroup of bacterial protein domains homologous to the carbohydrate-recognition domains (CRDs) of the C-type lectins; Region: CLECT_VCBS; cd03603
699034000093	ligand binding surface [chemical binding]; other site
699034000094	Transcriptional regulator [Transcription]; Region: LytR; COG1316
699034000095	Protein of unknown function (DUF4065); Region: DUF4065; pfam13274
699034000096	Protein of unknown function (DUF4065); Region: DUF4065; cl01445
699034000097	Protein of unknown function (DUF4065); Region: DUF4065; cl01445
699034000098	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000099	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000100	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
699034000101	activation loop (A-loop); other site
699034000102	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000103	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000104	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000105	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000106	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000107	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
699034000108	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
699034000109	Catalytic site [active]
699034000110	The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the...; Region: Peptidase_S24_S26; cl10465
699034000111	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
699034000112	Helix-hairpin-helix containing domain; Region: HHH_4; pfam14490
699034000113	AAA domain; Region: AAA_30; pfam13604
699034000114	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538
699034000115	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034000116	non-specific DNA binding site [nucleotide binding]; other site
699034000117	salt bridge; other site
699034000118	sequence-specific DNA binding site [nucleotide binding]; other site
699034000119	Predicted phosphohydrolase (DHH superfamily) [General function prediction only]; Region: COG2404
699034000120	radical SAM enzyme, TIGR04100 family; Region: rSAM_pair_X
699034000121	FtsH Extracellular; Region: FtsH_ext; pfam06480
699034000122	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
699034000123	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034000124	Walker A motif; other site
699034000125	ATP binding site [chemical binding]; other site
699034000126	Walker B motif; other site
699034000127	arginine finger; other site
699034000128	Peptidase family M41; Region: Peptidase_M41; pfam01434
699034000129	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
699034000130	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034000131	non-specific DNA binding site [nucleotide binding]; other site
699034000132	salt bridge; other site
699034000133	sequence-specific DNA binding site [nucleotide binding]; other site
699034000134	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
699034000135	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cl03295
699034000136	nucleotide binding pocket [chemical binding]; other site
699034000137	K-X-D-G motif; other site
699034000138	catalytic site [active]
699034000139	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
699034000140	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
699034000141	Helix-hairpin-helix motif; Region: HHH_2; pfam12826
699034000142	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
699034000143	Dimer interface [polypeptide binding]; other site
699034000144	BRCT sequence motif; other site
699034000145	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
699034000146	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
699034000147	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
699034000148	active site
699034000149	DNA binding site [nucleotide binding]
699034000150	Int/Topo IB signature motif; other site
699034000151	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034000152	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034000153	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034000154	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034000155	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034000156	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034000157	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
699034000158	Probable transposase; Region: OrfB_IS605; pfam01385
699034000159	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
699034000160	Penicillinase repressor; Region: Penicillinase_R; cl17580
699034000161	transcriptional repressor DicA; Reviewed; Region: PRK09706
699034000162	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034000163	non-specific DNA binding site [nucleotide binding]; other site
699034000164	salt bridge; other site
699034000165	sequence-specific DNA binding site [nucleotide binding]; other site
699034000166	Penicillinase repressor; Region: Penicillinase_R; cl17580
699034000167	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
699034000168	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034000169	Walker A motif; other site
699034000170	ATP binding site [chemical binding]; other site
699034000171	Walker B motif; other site
699034000172	arginine finger; other site
699034000173	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
699034000174	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
699034000175	CRISPR/Cas system-associated protein Cas3; Region: Cas3_I; cd09639
699034000176	CRISPR-associated helicase Cas3; Region: cas3_core; TIGR01587
699034000177	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-B; cl18994
699034000178	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I-C; cl01465
699034000179	CRISPR/Cas system-associated RAMP superfamily protein Cas6; Region: Cas6-I-III; cl11443
699034000180	Uncharacterized conserved protein (DUF2196); Region: DUF2196; cl02044
699034000181	ASC-1 homology domain, ASC-1-like subfamily. The ASCH domain, a small beta-barrel domain found in all three kingdoms of life, resembles the RNA-binding PUA domain and may also interact with RNA. ASCH has been proposed to function as an RNA-binding domain...; Region: ASCH_ASC-1_like; cd06554
699034000182	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
699034000183	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
699034000184	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK07088
699034000185	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
699034000186	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
699034000187	Probable transposase; Region: OrfB_IS605; pfam01385
699034000188	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3883
699034000189	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; cl17361
699034000190	ribonucleoside-triphosphate reductase, adenosylcobalamin-dependent; Region: RTPR; TIGR02505
699034000191	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
699034000192	Protein of unknown function (DUF1653); Region: DUF1653; cl01949
699034000193	signal recognition particle protein; Provisional; Region: PRK10867
699034000194	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000195	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034000196	non-specific DNA binding site [nucleotide binding]; other site
699034000197	salt bridge; other site
699034000198	sequence-specific DNA binding site [nucleotide binding]; other site
699034000199	putative transposase; Provisional; Region: PHA02942
699034000200	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000201	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000202	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000203	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000204	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000205	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000206	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000207	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000208	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000209	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000210	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000211	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000212	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000213	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000214	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000215	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000216	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000217	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000218	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000219	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000220	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000221	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000222	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000223	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000224	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000225	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000226	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000227	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000228	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000229	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000230	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000231	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000232	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000233	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000234	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000235	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000236	Protein of unknown function (DUF3037); Region: DUF3037; pfam11236
699034000237	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000238	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000239	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000240	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000241	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000242	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000243	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000244	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000245	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000246	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034000247	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034000248	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034000249	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000250	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000251	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000252	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000253	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000254	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000255	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000256	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
699034000257	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
699034000258	Probable transposase; Region: OrfB_IS605; pfam01385
699034000259	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
699034000260	Predicted site-specific integrase-resolvase [DNA replication, recombination, and repair]; Region: COG2452
699034000261	Helix-Turn-Helix DNA binding domain of truncated MerR-like proteins; Region: HTH_MerR-trunc; cd04762
699034000262	DNA binding residues [nucleotide binding]
699034000263	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cl02788
699034000264	catalytic residues [active]
699034000265	catalytic nucleophile [active]
699034000266	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000267	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000268	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000269	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000270	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000271	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000272	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000273	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000274	Nuclease-related domain; Region: NERD; pfam08378
699034000275	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000276	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000277	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000278	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000279	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000280	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000281	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000282	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000283	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000284	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000285	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000286	alanyl-tRNA synthetase; Region: A-tRNA_syn_arch; TIGR03683
699034000287	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000288	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000289	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000290	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000291	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000292	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000293	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000294	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000295	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000296	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000297	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000298	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000299	potential frameshift: common BLAST hit: gi|302391857|ref|YP_003827677.1| HNH endonuclease
699034000300	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000301	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000302	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000303	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000304	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000305	Protein of unknown function (DUF342); Region: DUF342; cl19219
699034000306	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000307	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000308	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000309	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000310	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000311	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000312	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000313	Probable transposase; Region: OrfB_IS605; pfam01385
699034000314	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000315	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000316	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000317	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000318	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000319	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000320	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000321	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000322	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000323	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000324	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000325	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000326	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000327	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000328	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000329	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000330	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000331	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000332	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000333	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000334	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000335	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000336	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000337	Predicted AAA-ATPase; Region: AAA-ATPase_like; pfam09820
699034000338	Protein of unknown function (DUF1703); Region: DUF1703; pfam08011
699034000339	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000340	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000341	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000342	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000343	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000344	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000345	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000346	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034000347	non-specific DNA binding site [nucleotide binding]; other site
699034000348	salt bridge; other site
699034000349	sequence-specific DNA binding site [nucleotide binding]; other site
699034000350	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000351	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000352	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000353	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000354	aminoacyl-tRNA ligase; Region: PLN02959
699034000355	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
699034000356	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034000357	non-specific DNA binding site [nucleotide binding]; other site
699034000358	salt bridge; other site
699034000359	sequence-specific DNA binding site [nucleotide binding]; other site
699034000360	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000361	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000362	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000363	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000364	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000365	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000366	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000367	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000368	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000369	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000370	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000371	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000372	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000373	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000374	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000375	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000376	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000377	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000378	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000379	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000380	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000381	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000382	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000383	potential frameshift: common BLAST hit: gi|302391857|ref|YP_003827677.1| HNH endonuclease
699034000384	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000385	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000386	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000387	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000388	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000389	Spore germination protein GerPC; Region: GerPC; pfam10737
699034000390	Cdc14 phosphatase binding protein N-terminus; Region: Cytokin_check_N; pfam10407
699034000391	Predicted HD-superfamily hydrolase [General function prediction only]; Region: COG3481
699034000392	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034000393	ABC transporter signature motif; other site
699034000394	Walker B; other site
699034000395	D-loop; other site
699034000396	H-loop/switch region; other site
699034000397	HerA helicase [Replication, recombination, and repair]; Region: COG0433
699034000398	Domain of unknown function DUF87; Region: DUF87; cl19135
699034000399	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
699034000400	S-adenosylmethionine binding site [chemical binding]; other site
699034000401	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
699034000402	Nucleotidyltransferase (NT) domain of 2'5'-oligoadenylate (2-5A)synthetase (2-5OAS) and class I CCA-adding enzyme; Region: NT_2-5OAS_ClassI-CCAase; cd05400
699034000403	active site
699034000404	NTP binding site [chemical binding]; other site
699034000405	metal binding triad [ion binding]; metal-binding site
699034000406	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
699034000407	lysozyme_like domain.  This contains several members including Soluble Lytic Transglycosylases (SLT), Goose Egg-White Lysozymes (GEWL), Hen Egg-White Lysozymes (HEWL), chitinases, bacteriophage lambda lysozymes, endolysins, autolysins, and chitosanases; Region: lysozyme_like; cl00222
699034000408	catalytic residue [active]
699034000409	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
699034000410	Peptidase family M23; Region: Peptidase_M23; pfam01551
699034000411	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
699034000412	NlpC/P60 family; Region: NLPC_P60; pfam00877
699034000413	7TM diverse intracellular signalling; Region: 7TMR-DISM_7TM; cl09440
699034000414	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
699034000415	AAA-like domain; Region: AAA_10; pfam12846
699034000416	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cd01983
699034000417	Domain of unknown function DUF87; Region: DUF87; cl19135
699034000418	PrgI family protein; Region: PrgI; pfam12666
699034000419	RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; Region: SigBFG; TIGR02980
699034000420	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
699034000421	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
699034000422	DNA binding residues [nucleotide binding]
699034000423	Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold; Region: Thioredoxin_like; cl00388
699034000424	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
699034000425	metal ion-dependent adhesion site (MIDAS); other site
699034000426	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
699034000427	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
699034000428	FtsX-like permease family; Region: FtsX; pfam02687
699034000429	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
699034000430	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
699034000431	Walker A/P-loop; other site
699034000432	ATP binding site [chemical binding]; other site
699034000433	Q-loop/lid; other site
699034000434	ABC transporter signature motif; other site
699034000435	Walker B; other site
699034000436	D-loop; other site
699034000437	H-loop/switch region; other site
699034000438	Flp pilus assembly protein, protease CpaA [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: CpaA; COG4960
699034000439	Type II secretion system (T2SS), protein F; Region: T2SF; cl19503
699034000440	HOOK protein; Region: HOOK; pfam05622
699034000441	Type II secretion system (T2SS), protein F; Region: T2SF; cl19503
699034000442	Flp pilus assembly protein, ATPase CpaF [Intracellular trafficking and secretion]; Region: CpaF; COG4962
699034000443	Walker A motif; other site
699034000444	ATP binding site [chemical binding]; other site
699034000445	Walker B motif; other site
699034000446	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
699034000447	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl19078
699034000448	active site
699034000449	phosphorylation site [posttranslational modification]
699034000450	intermolecular recognition site; other site
699034000451	dimerization interface [polypeptide binding]; other site
699034000452	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
699034000453	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
699034000454	Domains similar to fish antifreeze type III protein; Region: SAF; cl00555
699034000455	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
699034000456	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
699034000457	Replication-relaxation; Region: Replic_Relax; pfam13814
699034000458	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
699034000459	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034000460	non-specific DNA binding site [nucleotide binding]; other site
699034000461	salt bridge; other site
699034000462	sequence-specific DNA binding site [nucleotide binding]; other site
699034000463	Plasmid segregation protein ParM and similar proteins; Region: ParM_like; cd10227
699034000464	Mg binding site [ion binding]; other site
699034000465	nucleotide binding site [chemical binding]; other site
699034000466	putative protofilament interface [polypeptide binding]; other site
699034000467	Bacterial DNA polymerase III alpha subunit; Region: DNA_pol3_alpha; cl19160
699034000468	Helix-hairpin-helix motif; Region: HHH_6; pfam14579
699034000469	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
699034000470	generic binding surface I; other site
699034000471	generic binding surface II; other site
699034000472	Mitochondrial ATP synthase B chain precursor (ATP-synt_B); Region: Mt_ATP-synt_B; pfam05405
699034000473	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
699034000474	PHP domain; Region: PHP; pfam02811
699034000475	active site
699034000476	Bacterial DNA polymerase III alpha subunit; Region: DNA_pol3_alpha; cl19160
699034000477	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
699034000478	metal ion-dependent adhesion site (MIDAS); other site
699034000479	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034000480	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
699034000481	Walker A motif; other site
699034000482	ATP binding site [chemical binding]; other site
699034000483	Walker B motif; other site
699034000484	arginine finger; other site
699034000485	DNA primase, catalytic core; Region: dnaG; TIGR01391
699034000486	CHC2 zinc finger; Region: zf-CHC2; cl17510
699034000487	Domain of unknown function (DUF3854); Region: DUF3854; pfam12965
699034000488	generic binding surface I; other site
699034000489	Replication protein A, class 2b aminoacyl-tRNA synthetases, and related proteins with oligonucleotide/oligosaccharide (OB) fold; Region: RPA_2b-aaRSs_OBF_like; cl09930
699034000490	generic binding surface II; other site
699034000491	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
699034000492	active site
699034000493	catalytic site [active]
699034000494	substrate binding site [chemical binding]; other site
699034000495	Protein of unknown function (DUF1273); Region: DUF1273; cl01859
699034000496	Protein of unknown function (DUF3267); Region: DUF3267; pfam11667
699034000497	potential frameshift: common BLAST hit: gi|18310965|ref|NP_562899.1| DNA topoisomerase
699034000498	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
699034000499	Zn2+ binding site [ion binding]; other site
699034000500	Mg2+ binding site [ion binding]; other site
699034000501	Helix-hairpin-helix containing domain; Region: HHH_4; pfam14490
699034000502	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
699034000503	AAA domain; Region: AAA_11; pfam13086
699034000504	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034000505	Walker A motif; other site
699034000506	ATP binding site [chemical binding]; other site
699034000507	Walker B motif; other site
699034000508	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538
699034000509	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034000510	active site
699034000511	phosphorylation site [posttranslational modification]
699034000512	intermolecular recognition site; other site
699034000513	dimerization interface [polypeptide binding]; other site
699034000514	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
699034000515	RNA binding site [nucleotide binding]; other site
699034000516	Domain of unknown function DUF87; Region: DUF87; cl19135
699034000517	AAA-like domain; Region: AAA_10; pfam12846
699034000518	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cl00250
699034000519	Endodeoxyribonuclease RusA; Region: RusA; pfam05866
699034000520	Ribosomally synthesized peptide in Bacteroidetes; Region: Bacteroid_pep; cl15739
699034000521	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
699034000522	active site
699034000523	metal binding site [ion binding]; metal-binding site
699034000524	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419
699034000525	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034000526	Walker A/P-loop; other site
699034000527	ATP binding site [chemical binding]; other site
699034000528	Transglycosylase; Region: Transgly; pfam00912
699034000529	Transglycosylase; Region: Transgly; cl19357
699034000530	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
699034000531	Copper amine oxidase N-terminal domain; Region: Cu_amine_oxidN1; pfam07833
699034000532	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2268
699034000533	SPFH domain / Band 7 family; Region: Band_7; pfam01145
699034000534	core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily; Region: SPFH_like; cl19107
699034000535	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000536	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000537	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000538	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000539	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000540	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000541	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000542	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000543	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000544	Domain of unknown function (DUF955); Region: DUF955; cl01076
699034000545	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000546	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034000547	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
699034000548	DnaA N-terminal domain; Region: DnaA_N; pfam11638
699034000549	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034000550	Walker A motif; other site
699034000551	ATP binding site [chemical binding]; other site
699034000552	Walker B motif; other site
699034000553	arginine finger; other site
699034000554	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
699034000555	DnaA box-binding interface [nucleotide binding]; other site
699034000556	DNA polymerase III subunit beta; Validated; Region: PRK05643
699034000557	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
699034000558	putative DNA binding surface [nucleotide binding]; other site
699034000559	dimer interface [polypeptide binding]; other site
699034000560	beta-clamp/clamp loader binding surface; other site
699034000561	beta-clamp/translesion DNA polymerase binding surface; other site
699034000562	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
699034000563	RNA binding surface [nucleotide binding]; other site
699034000564	recombination protein F; Reviewed; Region: recF; PRK00064
699034000565	ATP-binding cassette domain of RecF; Region: ABC_RecF; cd03242
699034000566	Walker A/P-loop; other site
699034000567	ATP binding site [chemical binding]; other site
699034000568	Q-loop/lid; other site
699034000569	ABC transporter signature motif; other site
699034000570	Walker B; other site
699034000571	D-loop; other site
699034000572	H-loop/switch region; other site
699034000573	DNA gyrase subunit B; Validated; Region: gyrB; PRK05644
699034000574	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034000575	ATP binding site [chemical binding]; other site
699034000576	Mg2+ binding site [ion binding]; other site
699034000577	G-X-G motif; other site
699034000578	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
699034000579	anchoring element; other site
699034000580	dimer interface [polypeptide binding]; other site
699034000581	ATP binding site [chemical binding]; other site
699034000582	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
699034000583	active site
699034000584	putative metal-binding site [ion binding]; other site
699034000585	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
699034000586	DNA gyrase subunit A; Validated; Region: PRK05560
699034000587	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
699034000588	CAP-like domain; other site
699034000589	active site
699034000590	primary dimer interface [polypeptide binding]; other site
699034000591	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
699034000592	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
699034000593	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
699034000594	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
699034000595	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
699034000596	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
699034000597	YtxH-like protein; Region: YtxH; pfam12732
699034000598	alpha-ketoglutarate transporter; Provisional; Region: PRK10406
699034000599	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
699034000600	anti sigma factor interaction site; other site
699034000601	regulatory phosphorylation site [posttranslational modification]; other site
699034000602	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034000603	ATP binding site [chemical binding]; other site
699034000604	Mg2+ binding site [ion binding]; other site
699034000605	G-X-G motif; other site
699034000606	RNA polymerase sigma-70 factor, sigma-B/F/G subfamily; Region: SigBFG; TIGR02980
699034000607	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
699034000608	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
699034000609	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257
699034000610	DNA binding residues [nucleotide binding]
699034000611	potential RNA of insufficient length (23S ribosomal RNA)
699034000612	potential RNA of insufficient length (23S ribosomal RNA)
699034000613	Predicted small molecule binding protein (contains 3H domain) [General function prediction only]; Region: COG1827
699034000614	HTH domain; Region: HTH_11; pfam08279
699034000615	3H domain; Region: 3H; pfam02829
699034000616	Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane]; Region: MscS; COG0668
699034000617	Conserved TM helix; Region: TM_helix; pfam05552
699034000618	Mechanosensitive ion channel; Region: MS_channel; pfam00924
699034000619	seryl-tRNA synthetase; Provisional; Region: PRK05431
699034000620	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
699034000621	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
699034000622	dimer interface [polypeptide binding]; other site
699034000623	active site
699034000624	motif 1; other site
699034000625	motif 2; other site
699034000626	motif 3; other site
699034000627	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
699034000628	nucleoside/Zn binding site; other site
699034000629	dimer interface [polypeptide binding]; other site
699034000630	catalytic motif [active]
699034000631	potential protein location (hypothetical protein CDBI1_00080 [Clostridium difficile BI1]) that overlaps RNA (tRNA-S)
699034000632	DNA polymerase III subunits gamma and tau; Validated; Region: PRK05563
699034000633	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034000634	Walker A motif; other site
699034000635	ATP binding site [chemical binding]; other site
699034000636	Walker B motif; other site
699034000637	arginine finger; other site
699034000638	DNA polymerase III subunits gamma and tau domain III; Region: DNA_pol3_gamma3; pfam12169
699034000639	hypothetical protein; Validated; Region: PRK00153
699034000640	recombination protein RecR; Reviewed; Region: recR; PRK00076
699034000641	RecR protein; Region: RecR; pfam02132
699034000642	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
699034000643	putative active site [active]
699034000644	putative metal-binding site [ion binding]; other site
699034000645	tetramer interface [polypeptide binding]; other site
699034000646	diacylglycerol glucosyltransferase; Provisional; Region: PRK13609
699034000647	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
699034000648	Monogalactosyldiacylglycerol (MGDG) synthase; Region: MGDG_synth; pfam06925
699034000649	potential RNA of insufficient length (23S ribosomal RNA)
699034000650	potential protein location (hypothetical protein CDBI1_00110 [Clostridium difficile BI1]) that overlaps RNA (tRNA-L)
699034000651	pyruvate carboxylase; Reviewed; Region: PRK12999
699034000652	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
699034000653	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
699034000654	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
699034000655	Pyruvate carboxylase and Transcarboxylase 5S, carboxyltransferase domain; Region: DRE_TIM_PC_TC_5S; cd07937
699034000656	active site
699034000657	catalytic residues [active]
699034000658	metal binding site [ion binding]; metal-binding site
699034000659	homodimer binding site [polypeptide binding]; other site
699034000660	Conserved carboxylase domain; Region: PYC_OADA; pfam02436
699034000661	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
699034000662	carboxyltransferase (CT) interaction site; other site
699034000663	biotinylation site [posttranslational modification]; other site
699034000664	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
699034000665	elongation factor G; Reviewed; Region: PRK12740
699034000666	G1 box; other site
699034000667	GTP/Mg2+ binding site [chemical binding]; other site
699034000668	G2 box; other site
699034000669	Switch I region; other site
699034000670	G3 box; other site
699034000671	Switch II region; other site
699034000672	G4 box; other site
699034000673	G5 box; other site
699034000674	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
699034000675	Elongation Factor G, domain II; Region: EFG_II; pfam14492
699034000676	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
699034000677	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
699034000678	Firmicute transcriptional repressor of class III stress genes (CtsR); Region: CtsR; pfam05848
699034000679	Modulator of heat shock repressor CtsR, McsA [Signal transduction    mechanisms]; Region: COG3880
699034000680	UvrB/uvrC motif; Region: UVR; pfam02151
699034000681	ATP:guanido phosphotransferase; Provisional; Region: PRK01059
699034000682	Phosphagen (guanidino) kinases found in bacteria; Region: bacterial_phosphagen_kinase; cd07930
699034000683	ADP binding site [chemical binding]; other site
699034000684	phosphagen binding site; other site
699034000685	substrate specificity loop; other site
699034000686	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
699034000687	Clp amino terminal domain; Region: Clp_N; pfam02861
699034000688	Clp amino terminal domain; Region: Clp_N; pfam02861
699034000689	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034000690	Walker A motif; other site
699034000691	ATP binding site [chemical binding]; other site
699034000692	Walker B motif; other site
699034000693	arginine finger; other site
699034000694	UvrB/uvrC motif; Region: UVR; pfam02151
699034000695	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034000696	Walker A motif; other site
699034000697	ATP binding site [chemical binding]; other site
699034000698	Walker B motif; other site
699034000699	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
699034000700	DNA repair protein RadA; Provisional; Region: PRK11823
699034000701	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
699034000702	Walker A motif/ATP binding site; other site
699034000703	ATP binding site [chemical binding]; other site
699034000704	Walker B motif; other site
699034000705	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
699034000706	DNA integrity scanning protein DisA; Provisional; Region: PRK13482
699034000707	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
699034000708	DisA bacterial checkpoint controller linker region; Region: DisA-linker; pfam10635
699034000709	H3TH domains of structure-specific 5' nucleases (or flap endonuclease-1-like) involved in DNA replication, repair, and recombination; Region: H3TH_StructSpec-5'-nucleases; cl14815
699034000710	Integral membrane protein (PIN domain superfamily) [General function prediction only]; Region: COG4956
699034000711	PIN domain of Thermus Thermophilus Hb8, uncharacterized Bacillus subtilis YacL, and other bacterial homologs; Region: PIN_YacL; cd09877
699034000712	putative active site [active]
699034000713	Cupin domain; Region: Cupin_2; cl17218
699034000714	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
699034000715	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
699034000716	Endoglucanase [Carbohydrate transport and metabolism]; Region: BglC; COG2730
699034000717	Beta-xylosidase [Carbohydrate transport and metabolism]; Region: XynB; COG3507
699034000718	Glycosyl hydrolase family 43, beta-D-xylosidase; Region: GH43_XYL_1; cd09000
699034000719	inhibitor binding site; inhibition site
699034000720	active site
699034000721	MFS/sugar transport protein; Region: MFS_2; pfam13347
699034000722	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
699034000723	putative substrate translocation pore; other site
699034000724	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
699034000725	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
699034000726	non-specific DNA interactions [nucleotide binding]; other site
699034000727	DNA binding site [nucleotide binding]
699034000728	sequence specific DNA binding site [nucleotide binding]; other site
699034000729	putative cAMP binding site [chemical binding]; other site
699034000730	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
699034000731	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
699034000732	tetramer interface [polypeptide binding]; other site
699034000733	TPP-binding site [chemical binding]; other site
699034000734	heterodimer interface [polypeptide binding]; other site
699034000735	phosphorylation loop region [posttranslational modification]
699034000736	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
699034000737	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
699034000738	alpha subunit interface [polypeptide binding]; other site
699034000739	TPP binding site [chemical binding]; other site
699034000740	heterodimer interface [polypeptide binding]; other site
699034000741	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
699034000742	dihydrolipoamide acetyltransferase; Provisional; Region: PRK14843
699034000743	e3 binding domain; Region: E3_binding; pfam02817
699034000744	e3 binding domain; Region: E3_binding; pfam02817
699034000745	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
699034000746	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
699034000747	E3 interaction surface; other site
699034000748	lipoyl attachment site [posttranslational modification]; other site
699034000749	dihydrolipoamide dehydrogenase; Region: lipoamide_DH; TIGR01350
699034000750	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
699034000751	Pyridine nucleotide-disulphide oxidoreductase, dimerization domain; Region: Pyr_redox_dim; pfam02852
699034000752	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
699034000753	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034000754	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
699034000755	Walker A motif; other site
699034000756	ATP binding site [chemical binding]; other site
699034000757	Walker B motif; other site
699034000758	arginine finger; other site
699034000759	PRD domain; Region: PRD; pfam00874
699034000760	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
699034000761	active pocket/dimerization site; other site
699034000762	active site
699034000763	phosphorylation site [posttranslational modification]
699034000764	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
699034000765	active site
699034000766	phosphorylation site [posttranslational modification]
699034000767	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
699034000768	active site
699034000769	phosphorylation site [posttranslational modification]
699034000770	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
699034000771	active site
699034000772	P-loop; other site
699034000773	phosphorylation site [posttranslational modification]
699034000774	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
699034000775	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
699034000776	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cl00214
699034000777	intersubunit interface [polypeptide binding]; other site
699034000778	active site
699034000779	Zn2+ binding site [ion binding]; other site
699034000780	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
699034000781	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
699034000782	substrate binding site; other site
699034000783	dimer interface; other site
699034000784	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
699034000785	homotrimer interaction site [polypeptide binding]; other site
699034000786	zinc binding site [ion binding]; other site
699034000787	CDP-binding sites; other site
699034000788	prolyl-tRNA synthetase; Provisional; Region: PRK09194
699034000789	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
699034000790	dimer interface [polypeptide binding]; other site
699034000791	motif 1; other site
699034000792	active site
699034000793	motif 2; other site
699034000794	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
699034000795	putative deacylase active site [active]
699034000796	motif 3; other site
699034000797	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
699034000798	anticodon binding site; other site
699034000799	prolyl-tRNA synthetase; Provisional; Region: PRK08661
699034000800	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_arch_euk; cd00778
699034000801	dimer interface [polypeptide binding]; other site
699034000802	motif 1; other site
699034000803	active site
699034000804	motif 2; other site
699034000805	motif 3; other site
699034000806	ProRS Prolyl-anticodon binding domain, long version found predominantly in eukaryotes and archaea. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in...; Region: ProRS_anticodon_zinc; cd00862
699034000807	anticodon binding site; other site
699034000808	zinc-binding site [ion binding]; other site
699034000809	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
699034000810	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
699034000811	active site
699034000812	HIGH motif; other site
699034000813	KMSKS motif; other site
699034000814	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
699034000815	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
699034000816	active site
699034000817	HIGH motif; other site
699034000818	KMSKS motif; other site
699034000819	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
699034000820	tRNA binding surface [nucleotide binding]; other site
699034000821	anticodon binding site; other site
699034000822	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
699034000823	active site
699034000824	metal binding site [ion binding]; metal-binding site
699034000825	dimerization interface [polypeptide binding]; other site
699034000826	Thymidylate synthase complementing protein; Region: Thy1; cl03630
699034000827	Thymidylate synthase and pyrimidine hydroxymethylase: Thymidylate synthase (TS) and deoxycytidylate hydroxymethylase (dCMP-HMase) are homologs that catalyze analogous alkylation of C5 of pyrimidine nucleotides. Both enzymes are involved in the...; Region: TS_Pyrimidine_HMase; cd00351
699034000828	dimerization interface [polypeptide binding]; other site
699034000829	active site
699034000830	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
699034000831	folate binding site [chemical binding]; other site
699034000832	NADP+ binding site [chemical binding]; other site
699034000833	SIR2-like domain; Region: SIR2_2; pfam13289
699034000834	ThiC family; Region: ThiC; cl08031
699034000835	Thymidylate synthase complementing protein; Region: Thy1; cl03630
699034000836	rRNA methylase, putative, group 3; Region: rRNA_methyl_3; TIGR00186
699034000837	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
699034000838	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
699034000839	YacP-like NYN domain; Region: NYN_YacP; pfam05991
699034000840	RNA polymerase factor sigma-70; Validated; Region: PRK08295
699034000841	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
699034000842	elongation factor Tu; Reviewed; Region: PRK00049
699034000843	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
699034000844	G1 box; other site
699034000845	GEF interaction site [polypeptide binding]; other site
699034000846	GTP/Mg2+ binding site [chemical binding]; other site
699034000847	Switch I region; other site
699034000848	G2 box; other site
699034000849	G3 box; other site
699034000850	Switch II region; other site
699034000851	G4 box; other site
699034000852	G5 box; other site
699034000853	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
699034000854	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
699034000855	Antibiotic Binding Site [chemical binding]; other site
699034000856	50S ribosomal protein L33; Validated; Region: rpmG; PRK00504
699034000857	preprotein translocase subunit SecE; Reviewed; Region: secE; PRK07597
699034000858	transcription antitermination protein NusG; Validated; Region: nusG; PRK05609
699034000859	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
699034000860	putative homodimer interface [polypeptide binding]; other site
699034000861	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
699034000862	heterodimer interface [polypeptide binding]; other site
699034000863	homodimer interface [polypeptide binding]; other site
699034000864	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
699034000865	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
699034000866	23S rRNA interface [nucleotide binding]; other site
699034000867	L7/L12 interface [polypeptide binding]; other site
699034000868	putative thiostrepton binding site; other site
699034000869	L25 interface [polypeptide binding]; other site
699034000870	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
699034000871	mRNA/rRNA interface [nucleotide binding]; other site
699034000872	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
699034000873	23S rRNA interface [nucleotide binding]; other site
699034000874	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
699034000875	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
699034000876	core dimer interface [polypeptide binding]; other site
699034000877	peripheral dimer interface [polypeptide binding]; other site
699034000878	L10 interface [polypeptide binding]; other site
699034000879	L11 interface [polypeptide binding]; other site
699034000880	putative EF-Tu interaction site [polypeptide binding]; other site
699034000881	putative EF-G interaction site [polypeptide binding]; other site
699034000882	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05653
699034000883	classical (c) SDRs; Region: SDR_c; cd05233
699034000884	NAD(P) binding site [chemical binding]; other site
699034000885	active site
699034000886	DNA-directed RNA polymerase subunit beta; Reviewed; Region: rpoB; PRK00405
699034000887	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
699034000888	RPB12 interaction site [polypeptide binding]; other site
699034000889	RNA polymerase beta subunit; Region: RNA_pol_Rpb2_1; cl19478
699034000890	RPB1 interaction site [polypeptide binding]; other site
699034000891	RNA polymerase beta subunit external 1 domain; Region: RNA_pol_Rpb2_45; pfam10385
699034000892	RPB10 interaction site [polypeptide binding]; other site
699034000893	RPB11 interaction site [polypeptide binding]; other site
699034000894	RPB3 interaction site [polypeptide binding]; other site
699034000895	DNA-directed RNA polymerase subunit beta'; Provisional; Region: PRK00566
699034000896	Largest subunit (beta') of bacterial DNA-dependent RNA polymerase (RNAP), N-terminal domain; Region: RNAP_beta'_N; cd01609
699034000897	beta and beta' interface [polypeptide binding]; other site
699034000898	beta' and sigma factor interface [polypeptide binding]; other site
699034000899	Zn-binding [ion binding]; other site
699034000900	active site region [active]
699034000901	catalytic site [active]
699034000902	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
699034000903	Rpb1 (beta') - Rpb6 (omega) interaction site [polypeptide binding]; other site
699034000904	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
699034000905	G-loop; other site
699034000906	DNA binding site [nucleotide binding]
699034000907	Apocytochrome F, C-terminal; Region: Apocytochr_F_C; cl03168
699034000908	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
699034000909	S17 interaction site [polypeptide binding]; other site
699034000910	S8 interaction site; other site
699034000911	16S rRNA interaction site [nucleotide binding]; other site
699034000912	streptomycin interaction site [chemical binding]; other site
699034000913	23S rRNA interaction site [nucleotide binding]; other site
699034000914	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
699034000915	30S ribosomal protein S7; Validated; Region: PRK05302
699034000916	elongation factor G; Reviewed; Region: PRK00007
699034000917	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
699034000918	G1 box; other site
699034000919	putative GEF interaction site [polypeptide binding]; other site
699034000920	GTP/Mg2+ binding site [chemical binding]; other site
699034000921	Switch I region; other site
699034000922	G2 box; other site
699034000923	G3 box; other site
699034000924	Switch II region; other site
699034000925	G4 box; other site
699034000926	G5 box; other site
699034000927	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
699034000928	Elongation Factor G, domain II; Region: EFG_II; pfam14492
699034000929	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
699034000930	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
699034000931	elongation factor Tu; Reviewed; Region: PRK00049
699034000932	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
699034000933	G1 box; other site
699034000934	GEF interaction site [polypeptide binding]; other site
699034000935	GTP/Mg2+ binding site [chemical binding]; other site
699034000936	Switch I region; other site
699034000937	G2 box; other site
699034000938	G3 box; other site
699034000939	Switch II region; other site
699034000940	G4 box; other site
699034000941	G5 box; other site
699034000942	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
699034000943	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
699034000944	Antibiotic Binding Site [chemical binding]; other site
699034000945	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
699034000946	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
699034000947	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
699034000948	50S ribosomal protein L23; Reviewed; Region: rplW; PRK05738
699034000949	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
699034000950	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
699034000951	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
699034000952	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
699034000953	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
699034000954	putative translocon binding site; other site
699034000955	protein-rRNA interface [nucleotide binding]; other site
699034000956	30S ribosomal protein S3; Reviewed; Region: rpsC; PRK00310
699034000957	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
699034000958	G-X-X-G motif; other site
699034000959	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
699034000960	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
699034000961	23S rRNA interface [nucleotide binding]; other site
699034000962	5S rRNA interface [nucleotide binding]; other site
699034000963	putative antibiotic binding site [chemical binding]; other site
699034000964	L25 interface [polypeptide binding]; other site
699034000965	L27 interface [polypeptide binding]; other site
699034000966	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
699034000967	23S rRNA interface [nucleotide binding]; other site
699034000968	putative translocon interaction site; other site
699034000969	signal recognition particle (SRP54) interaction site; other site
699034000970	L23 interface [polypeptide binding]; other site
699034000971	trigger factor interaction site; other site
699034000972	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
699034000973	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
699034000974	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
699034000975	RNA binding site [nucleotide binding]; other site
699034000976	Mu transposase, C-terminal; Region: Mu-transpos_C; pfam09299
699034000977	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
699034000978	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
699034000979	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
699034000980	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08061
699034000981	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
699034000982	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
699034000983	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
699034000984	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
699034000985	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
699034000986	5S rRNA interface [nucleotide binding]; other site
699034000987	L27 interface [polypeptide binding]; other site
699034000988	23S rRNA interface [nucleotide binding]; other site
699034000989	L5 interface [polypeptide binding]; other site
699034000990	30S ribosomal protein S5; Validated; Region: rpsE; PRK00550
699034000991	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
699034000992	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
699034000993	Ribosomal protein L30, which is found in eukaryotes and prokaryotes but not in archaea, is one of the smallest ribosomal proteins with a molecular mass of about 7kDa. L30 binds the 23SrRNA as well as the 5S rRNA and is one of five ribosomal proteins that...; Region: Ribosomal_L30; cd01658
699034000994	23S rRNA binding site [nucleotide binding]; other site
699034000995	50S ribosomal protein L15; Reviewed; Region: rplO; PRK05592
699034000996	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
699034000997	SecY translocase; Region: SecY; pfam00344
699034000998	adenylate kinase; Reviewed; Region: adk; PRK00279
699034000999	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
699034001000	AMP-binding site [chemical binding]; other site
699034001001	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
699034001002	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
699034001003	active site
699034001004	KOW: an acronym for the authors' surnames (Kyrpides, Ouzounis and Woese); Region: KOW; cl00354
699034001005	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
699034001006	rRNA binding site [nucleotide binding]; other site
699034001007	predicted 30S ribosome binding site; other site
699034001008	50S ribosomal protein L36; Reviewed; Region: rpmJ; PRK00465
699034001009	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
699034001010	30S ribosomal protein S11; Validated; Region: PRK05309
699034001011	30S ribosomal protein S4; Validated; Region: rpsD; PRK05327
699034001012	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
699034001013	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
699034001014	RNA binding surface [nucleotide binding]; other site
699034001015	DNA-directed RNA polymerase subunit alpha; Provisional; Region: PRK05182
699034001016	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
699034001017	alphaNTD - beta interaction site [polypeptide binding]; other site
699034001018	alphaNTD homodimer interface [polypeptide binding]; other site
699034001019	alphaNTD - beta' interaction site [polypeptide binding]; other site
699034001020	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
699034001021	50S ribosomal protein L17; Validated; Region: rplQ; PRK05591
699034001022	cobalt transporter ATP-binding subunit; Provisional; Region: PRK13633
699034001023	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
699034001024	Walker A/P-loop; other site
699034001025	ATP binding site [chemical binding]; other site
699034001026	Q-loop/lid; other site
699034001027	ABC transporter signature motif; other site
699034001028	Walker B; other site
699034001029	D-loop; other site
699034001030	H-loop/switch region; other site
699034001031	cobalt transporter ATP-binding subunit; Provisional; Region: cbiO; PRK13637
699034001032	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
699034001033	Walker A/P-loop; other site
699034001034	ATP binding site [chemical binding]; other site
699034001035	Q-loop/lid; other site
699034001036	ABC transporter signature motif; other site
699034001037	Walker B; other site
699034001038	D-loop; other site
699034001039	H-loop/switch region; other site
699034001040	ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism]; Region: CbiQ; COG0619
699034001041	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
699034001042	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
699034001043	dimerization interface 3.5A [polypeptide binding]; other site
699034001044	active site
699034001045	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
699034001046	23S rRNA interface [nucleotide binding]; other site
699034001047	L3 interface [polypeptide binding]; other site
699034001048	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
699034001049	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
699034001050	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
699034001051	active site
699034001052	metal binding site [ion binding]; metal-binding site
699034001053	potential RNA of insufficient length (23S ribosomal RNA)
699034001054	potential protein location (hypothetical protein CDBI1_00600 [Clostridium difficile BI1]) that overlaps RNA (tRNA-D)
699034001055	potential RNA of insufficient length (23S ribosomal RNA)
699034001056	aspartate aminotransferase; Provisional; Region: PRK05764
699034001057	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
699034001058	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034001059	homodimer interface [polypeptide binding]; other site
699034001060	catalytic residue [active]
699034001061	anaerobic ribonucleoside triphosphate reductase; Provisional; Region: PRK07111
699034001062	ATP cone domain; Region: ATP-cone; pfam03477
699034001063	Class III ribonucleotide reductase; Region: RNR_III; cd01675
699034001064	effector binding site; other site
699034001065	active site
699034001066	Zn binding site [ion binding]; other site
699034001067	glycine loop; other site
699034001068	4Fe-4S single cluster domain; Region: Fer4_12; pfam13353
699034001069	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
699034001070	FeS/SAM binding site; other site
699034001071	potential RNA of insufficient length (23S ribosomal RNA)
699034001072	potential RNA of insufficient length (23S ribosomal RNA)
699034001073	Uncharacterized conserved protein [Function unknown]; Region: COG1624
699034001074	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
699034001075	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4856
699034001076	YbbR-like protein; Region: YbbR; pfam07949
699034001077	phosphate butyryltransferase; Validated; Region: PRK05805
699034001078	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
699034001079	nucleotide binding site [chemical binding]; other site
699034001080	Acetokinase family; Region: Acetate_kinase; cl17229
699034001081	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
699034001082	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
699034001083	2-ketoisovalerate ferredoxin reductase; Validated; Region: PRK07119
699034001084	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
699034001085	dimer interface [polypeptide binding]; other site
699034001086	PYR/PP interface [polypeptide binding]; other site
699034001087	TPP binding site [chemical binding]; other site
699034001088	substrate binding site [chemical binding]; other site
699034001089	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
699034001090	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit [Energy production and conversion]; Region: PorB; COG1013
699034001091	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
699034001092	TPP-binding site [chemical binding]; other site
699034001093	Pyruvate ferredoxin/flavodoxin oxidoreductase; Region: POR; pfam01558
699034001094	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14316
699034001095	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
699034001096	active site
699034001097	substrate binding site [chemical binding]; other site
699034001098	metal binding site [ion binding]; metal-binding site
699034001099	glucosamine--fructose-6-phosphate aminotransferase; Reviewed; Region: PRK00331
699034001100	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
699034001101	glutaminase active site [active]
699034001102	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
699034001103	dimer interface [polypeptide binding]; other site
699034001104	active site
699034001105	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
699034001106	dimer interface [polypeptide binding]; other site
699034001107	active site
699034001108	Rhodanese-like domain; Region: Rhodanese; pfam00581
699034001109	active site residue [active]
699034001110	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
699034001111	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
699034001112	active site residue [active]
699034001113	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
699034001114	active site residue [active]
699034001115	Protein of unknown function (DUF1779); Region: DUF1779; pfam08680
699034001116	EPSP synthase (3-phosphoshikimate 1-carboxyvinyltransferase); Region: EPSP_synthase; pfam00275
699034001117	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
699034001118	hinge; other site
699034001119	active site
699034001120	Stage II sporulation protein; Region: SpoIID; pfam08486
699034001121	SpoIID/LytB domain; Region: SpoIID_LytB; TIGR02669
699034001122	Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane]; Region: NlpD; COG0739
699034001123	Peptidase family M23; Region: Peptidase_M23; pfam01551
699034001124	Stage III sporulation protein D; Region: SpoIIID; pfam12116
699034001125	rod shape-determining protein Mbl; Provisional; Region: PRK13928
699034001126	MreB and similar proteins; Region: MreB_like; cd10225
699034001127	nucleotide binding site [chemical binding]; other site
699034001128	Mg binding site [ion binding]; other site
699034001129	putative protofilament interaction site [polypeptide binding]; other site
699034001130	RodZ interaction site [polypeptide binding]; other site
699034001131	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
699034001132	Protein of unknown function (DUF1256); Region: DUF1256; cl06087
699034001133	S-adenosylmethionine synthetase; Validated; Region: PRK05250
699034001134	S-adenosylmethionine synthetase, N-terminal domain; Region: S-AdoMet_synt_N; pfam00438
699034001135	S-adenosylmethionine synthetase, central domain; Region: S-AdoMet_synt_M; pfam02772
699034001136	S-adenosylmethionine synthetase, C-terminal domain; Region: S-AdoMet_synt_C; pfam02773
699034001137	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
699034001138	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
699034001139	AAA domain; Region: AAA_30; pfam13604
699034001140	Family description; Region: UvrD_C_2; pfam13538
699034001141	Predicted amidophosphoribosyltransferases [General function prediction only]; Region: ComFC; COG1040
699034001142	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
699034001143	active site
699034001144	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
699034001145	PRD domain; Region: PRD; pfam00874
699034001146	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
699034001147	active site
699034001148	P-loop; other site
699034001149	phosphorylation site [posttranslational modification]
699034001150	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; Region: PTS_EIIA_2; pfam00359
699034001151	active site
699034001152	phosphorylation site [posttranslational modification]
699034001153	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
699034001154	methionine cluster; other site
699034001155	active site
699034001156	phosphorylation site [posttranslational modification]
699034001157	metal binding site [ion binding]; metal-binding site
699034001158	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
699034001159	active site
699034001160	P-loop; other site
699034001161	phosphorylation site [posttranslational modification]
699034001162	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
699034001163	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB); Region: GRDB; cl19416
699034001164	Glycosylasparaginase catalyzes the hydrolysis of the glycosylamide bond of asparagine-linked glycoproteins. This enzyme is an amidase located inside lysosomes. Mutation of this gene in humans causes a genetic disorder known as aspartylglycosaminuria (AGU)...; Region: Glycosylasparaginase; cd04513
699034001165	active site
699034001166	dimer interface [polypeptide binding]; other site
699034001167	catalytic nucleophile [active]
699034001168	dipeptidase PepV; Reviewed; Region: PRK07318
699034001169	M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides; Region: M20_PepV; cd03888
699034001170	active site
699034001171	metal binding site [ion binding]; metal-binding site
699034001172	Uncharacterized protein involved in copper resistance [Inorganic ion transport and metabolism]; Region: CutC; COG3142
699034001173	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
699034001174	30S subunit binding site; other site
699034001175	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
699034001176	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
699034001177	ATP binding site [chemical binding]; other site
699034001178	putative Mg++ binding site [ion binding]; other site
699034001179	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
699034001180	SecA Wing and Scaffold domain; Region: SecA_SW; pfam07516
699034001181	SEC-C motif; Region: SEC-C; pfam02810
699034001182	peptide chain release factor 2; Provisional; Region: PRK05589
699034001183	PCRF domain; Region: PCRF; pfam03462
699034001184	RF-1 domain; Region: RF-1; pfam00472
699034001185	Transcriptional accessory protein [Transcription]; Region: Tex; COG2183
699034001186	Tex-like protein N-terminal domain; Region: Tex_N; pfam09371
699034001187	Likely ribonuclease with RNase H fold; Region: YqgFc; smart00732
699034001188	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
699034001189	S1_Tex: The C-terminal S1 domain of a transcription accessory factor called Tex, which has been characterized in Bordetella pertussis and Pseudomonas aeruginosa. The tex gene is essential in Bortella pertusis and is named for its role in toxin expression; Region: S1_Tex; cd05685
699034001190	RNA binding site [nucleotide binding]; other site
699034001191	Imidazolonepropionase and related amidohydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: HutI; COG1228
699034001192	Metallo-dependent hydrolases, subgroup C is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_C; cd01309
699034001193	active site
699034001194	Predicted membrane protein [Function unknown]; Region: COG3601
699034001195	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034001196	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034001197	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034001198	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034001199	Predicted ATPase or kinase [General function prediction only]; Region: COG0802
699034001200	GTPase SAR1 and related small G proteins [General function prediction only]; Region: COG1100
699034001201	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
699034001202	Glycoprotease family; Region: Peptidase_M22; pfam00814
699034001203	ribosomal-protein-alanine acetyltransferase; Region: rimI; TIGR01575
699034001204	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
699034001205	Coenzyme A binding pocket [chemical binding]; other site
699034001206	UGMP family protein; Validated; Region: PRK09604
699034001207	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
699034001208	tRNA threonylcarbamoyl adenosine modification protein YeaZ; Region: T6A_YeaZ; TIGR03725
699034001209	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
699034001210	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
699034001211	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
699034001212	anaerobic ribonucleotide reductase-activating protein; Provisional; Region: nrdG; cl15804
699034001213	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl18962
699034001214	CAAX protease self-immunity; Region: Abi; pfam02517
699034001215	CAAX protease self-immunity; Region: Abi; pfam02517
699034001216	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cl14632
699034001217	active site
699034001218	metal binding site [ion binding]; metal-binding site
699034001219	Uncharacterized protein conserved in bacteria (DUF2316); Region: DUF2316; cl01805
699034001220	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
699034001221	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034001222	active site
699034001223	phosphorylation site [posttranslational modification]
699034001224	intermolecular recognition site; other site
699034001225	dimerization interface [polypeptide binding]; other site
699034001226	LytTr DNA-binding domain; Region: LytTR; smart00850
699034001227	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
699034001228	ATP-binding cassette domain of multidrug resistance protein-like transporters; Region: ABCC_MRP_Like; cd03228
699034001229	Walker A/P-loop; other site
699034001230	ATP binding site [chemical binding]; other site
699034001231	Q-loop/lid; other site
699034001232	ABC transporter signature motif; other site
699034001233	Walker B; other site
699034001234	D-loop; other site
699034001235	H-loop/switch region; other site
699034001236	Cys-rich peptide radical SAM maturase CcpM; Region: rSAM_ocin_clost; TIGR04068
699034001237	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
699034001238	FeS/SAM binding site; other site
699034001239	peptide maturation system protein, TIGR04066 family; Region: nat_prod_clost
699034001240	peptide maturation system acyl carrier-related protein; Region: ocin_ACP_rel; TIGR04069
699034001241	amino acid transporter; Region: 2A0306; TIGR00909
699034001242	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
699034001243	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
699034001244	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
699034001245	metal binding site [ion binding]; metal-binding site
699034001246	dimer interface [polypeptide binding]; other site
699034001247	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
699034001248	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034001249	Walker A motif; other site
699034001250	ATP binding site [chemical binding]; other site
699034001251	Walker B motif; other site
699034001252	arginine finger; other site
699034001253	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
699034001254	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
699034001255	ligand binding site [chemical binding]; other site
699034001256	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
699034001257	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_8; cd13134
699034001258	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
699034001259	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
699034001260	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034001261	ABC transporter; Region: ABC_tran_2; pfam12848
699034001262	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
699034001263	redox-sensing transcriptional repressor Rex; Provisional; Region: PRK05472
699034001264	Putative DNA-binding protein N-terminus; Region: Put_DNA-bind_N; pfam06971
699034001265	CoA binding domain; Region: CoA_binding; pfam02629
699034001266	Formylmethanofuran dehydrogenase subunit E [Energy production and conversion]; Region: COG2191
699034001267	FmdE, Molybdenum formylmethanofuran dehydrogenase operon; Region: FmdE; pfam02663
699034001268	Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; pfam01258
699034001269	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
699034001270	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
699034001271	CapA and related proteins, metallophosphatase domain; Region: MPP_CapA; cd07381
699034001272	putative active site [active]
699034001273	putative metal binding site [ion binding]; other site
699034001274	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
699034001275	ACS interaction site; other site
699034001276	CODH interaction site; other site
699034001277	metal cluster binding site [ion binding]; other site
699034001278	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
699034001279	Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only]; Region: HcaD; COG0446
699034001280	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
699034001281	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
699034001282	Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]; Region: Cfa; COG2230
699034001283	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
699034001284	S-adenosylmethionine binding site [chemical binding]; other site
699034001285	Pyruvate ferredoxin/flavodoxin oxidoreductase; Region: POR; cl00546
699034001286	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
699034001287	Glu/Leu/Phe/Val dehydrogenase, dimerization domain; Region: ELFV_dehydrog_N; pfam02812
699034001288	NAD(P) binding domain of glutamate dehydrogenase, subgroup 1; Region: NAD_bind_1_Glu_DH; cd01076
699034001289	NAD(P) binding site [chemical binding]; other site
699034001290	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
699034001291	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
699034001292	SH3 domain protein [Signal transduction mechanisms]; Region: COG3103
699034001293	Bacterial SH3 domain; Region: SH3_3; pfam08239
699034001294	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
699034001295	NlpC/P60 family; Region: NLPC_P60; pfam00877
699034001296	aspartate carbamoyltransferase catalytic subunit; Provisional; Region: pyrB; PRK00856
699034001297	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
699034001298	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
699034001299	dihydroorotate dehydrogenase electron transfer subunit; Reviewed; Region: PRK00054
699034001300	FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)-dihydroorotate to...; Region: DHOD_e_trans; cd06218
699034001301	FAD binding pocket [chemical binding]; other site
699034001302	FAD binding motif [chemical binding]; other site
699034001303	phosphate binding motif [ion binding]; other site
699034001304	beta-alpha-beta structure motif; other site
699034001305	NAD binding pocket [chemical binding]; other site
699034001306	Iron coordination center [ion binding]; other site
699034001307	Dihydroorotate dehydrogenase (DHOD) class 1B FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the precursor of all pyrimidine...; Region: DHOD_1B_like; cd04740
699034001308	heterodimer interface [polypeptide binding]; other site
699034001309	active site
699034001310	FMN binding site [chemical binding]; other site
699034001311	homodimer interface [polypeptide binding]; other site
699034001312	substrate binding site [chemical binding]; other site
699034001313	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
699034001314	active site
699034001315	Ketopantoate reductase PanE/ApbA; Region: ApbA; pfam02558
699034001316	2-dehydropantoate 2-reductase; Region: apbA_panE; TIGR00745
699034001317	Ketopantoate reductase PanE/ApbA C terminal; Region: ApbA_C; pfam08546
699034001318	Transcriptional regulator [Transcription]; Region: LysR; COG0583
699034001319	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
699034001320	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
699034001321	putative dimerization interface [polypeptide binding]; other site
699034001322	Conserved hypothetical protein 698; Region: Cons_hypoth698; cl01075
699034001323	8-oxoguanine DNA glycosylase, N-terminal domain; Region: OGG_N; pfam07934
699034001324	8-oxoguanine DNA-glycosylase (ogg); Region: ogg; TIGR00588
699034001325	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
699034001326	minor groove reading motif; other site
699034001327	helix-hairpin-helix signature motif; other site
699034001328	substrate binding pocket [chemical binding]; other site
699034001329	active site
699034001330	cardiolipin synthetase; Reviewed; Region: cls; PRK01642
699034001331	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
699034001332	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
699034001333	putative active site [active]
699034001334	catalytic site [active]
699034001335	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
699034001336	putative active site [active]
699034001337	catalytic site [active]
699034001338	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
699034001339	oligomerisation interface [polypeptide binding]; other site
699034001340	mobile loop; other site
699034001341	roof hairpin; other site
699034001342	chaperonin GroEL; Reviewed; Region: groEL; PRK12850
699034001343	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
699034001344	ring oligomerisation interface [polypeptide binding]; other site
699034001345	ATP/Mg binding site [chemical binding]; other site
699034001346	stacking interactions; other site
699034001347	hinge regions; other site
699034001348	NCAIR mutase (PurE)-related proteins [General function prediction only]; Region: COG1691
699034001349	AIR carboxylase; Region: AIRC; smart01001
699034001350	Protein of unknown function DUF111; Region: DUF111; cl03398
699034001351	Protein of unknown function DUF111; Region: DUF111; cl03398
699034001352	GMP synthase; Reviewed; Region: guaA; PRK00074
699034001353	Type 1 glutamine amidotransferase (GATase1) domain found in GMP synthetase; Region: GATase1_GMP_Synthase; cd01742
699034001354	AMP/PPi binding site [chemical binding]; other site
699034001355	candidate oxyanion hole; other site
699034001356	catalytic triad [active]
699034001357	potential glutamine specificity residues [chemical binding]; other site
699034001358	The C-terminal domain of GMP synthetase. It contains two subdomains; the ATP pyrophosphatase domain which closes to the N-termial and the dimerization domain at C-terminal end. The ATP-PPase is a twisted, five-stranded parallel beta-sheet sandwiched...; Region: GMP_synthase_C; cd01997
699034001359	ATP Binding subdomain [chemical binding]; other site
699034001360	Ligand Binding sites [chemical binding]; other site
699034001361	Dimerization subdomain; other site
699034001362	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
699034001363	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
699034001364	active site
699034001365	metal binding site [ion binding]; metal-binding site
699034001366	Transcriptional regulator [Transcription]; Region: LysR; COG0583
699034001367	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
699034001368	LysR substrate binding domain; Region: LysR_substrate; pfam03466
699034001369	dimerization interface [polypeptide binding]; other site
699034001370	Chromate transporter; Region: Chromate_transp; pfam02417
699034001371	Chromate transporter; Region: Chromate_transp; pfam02417
699034001372	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
699034001373	Excinuclease ATPase subunit [DNA replication, recombination, and repair]; Region: UvrA; COG0178
699034001374	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034001375	Walker A/P-loop; other site
699034001376	ATP binding site [chemical binding]; other site
699034001377	Q-loop/lid; other site
699034001378	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034001379	ABC transporter signature motif; other site
699034001380	Walker B; other site
699034001381	D-loop; other site
699034001382	H-loop/switch region; other site
699034001383	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034001384	Walker A/P-loop; other site
699034001385	ATP binding site [chemical binding]; other site
699034001386	Q-loop/lid; other site
699034001387	ABC transporter signature motif; other site
699034001388	Walker B; other site
699034001389	D-loop; other site
699034001390	H-loop/switch region; other site
699034001391	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
699034001392	metal binding site [ion binding]; metal-binding site
699034001393	active site
699034001394	I-site; other site
699034001395	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
699034001396	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
699034001397	PRD domain; Region: PRD; pfam00874
699034001398	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
699034001399	active site
699034001400	P-loop; other site
699034001401	phosphorylation site [posttranslational modification]
699034001402	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; Region: PTS_EIIA_2; pfam00359
699034001403	active site
699034001404	phosphorylation site [posttranslational modification]
699034001405	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
699034001406	active site
699034001407	phosphorylation site [posttranslational modification]
699034001408	putative PTS system fructose-like transporter subunit EIIC; Provisional; Region: PRK10478
699034001409	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
699034001410	active site
699034001411	P-loop; other site
699034001412	phosphorylation site [posttranslational modification]
699034001413	Tagatose 6 phosphate kinase; Region: Tagatose_6_P_K; cl09211
699034001414	Predicted hydrolase (HAD superfamily) [General function prediction only]; Region: COG1011
699034001415	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
699034001416	motif II; other site
699034001417	Coat F domain; Region: Coat_F; pfam07875
699034001418	NAD(P)H:flavin oxidoreductase-like family 1.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes; Region: NADPH_oxidoreductase_1; cd02150
699034001419	putative FMN binding site [chemical binding]; other site
699034001420	AIR carboxylase; Region: AIRC; pfam00731
699034001421	bacterial and archaeal 5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt_PurC; cd01415
699034001422	ATP binding site [chemical binding]; other site
699034001423	active site
699034001424	substrate binding site [chemical binding]; other site
699034001425	amidophosphoribosyltransferase; Region: purF; TIGR01134
699034001426	Glutamine amidotransferases class-II (GN-AT)_GPAT- type. This domain is found at the N-terminus of  glutamine phosphoribosylpyrophosphate (Prpp) amidotransferase (GPATase) . The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the...; Region: GPATase_N; cd00715
699034001427	active site
699034001428	tetramer interface [polypeptide binding]; other site
699034001429	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
699034001430	active site
699034001431	phosphoribosylaminoimidazole synthetase; Provisional; Region: PRK05385
699034001432	PurM (Aminoimidazole Ribonucleotide [AIR] synthetase), one of eleven enzymes required for purine biosynthesis, catalyzes the conversion of formylglycinamide ribonucleotide (FGAM) and ATP to AIR, ADP, and Pi, the fifth step in de novo purine biosynthesis; Region: PurM; cd02196
699034001433	dimerization interface [polypeptide binding]; other site
699034001434	putative ATP binding site [chemical binding]; other site
699034001435	Phosphoribosylglycinamide formyltransferase (GAR transformylase, GART); Region: FMT_core_GART; cd08645
699034001436	active site
699034001437	substrate binding site [chemical binding]; other site
699034001438	cosubstrate binding site; other site
699034001439	catalytic site [active]
699034001440	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Provisional; Region: purH; PRK00881
699034001441	Inosine monophosphate cyclohydrolase domain. This is the N-terminal domain in the purine biosynthesis pathway protein ATIC (purH). The bifunctional ATIC protein contains a C-terminal  ATIC formylase domain that formylates...; Region: IMPCH; cd01421
699034001442	purine monophosphate binding site [chemical binding]; other site
699034001443	dimer interface [polypeptide binding]; other site
699034001444	putative catalytic residues [active]
699034001445	AICARFT/IMPCHase bienzyme; Region: AICARFT_IMPCHas; smart00798
699034001446	phosphoribosylamine--glycine ligase; Provisional; Region: PRK00885
699034001447	Phosphoribosylglycinamide synthetase, N domain; Region: GARS_N; pfam02844
699034001448	Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Region: GARS_A; pfam01071
699034001449	Phosphoribosylglycinamide synthetase, C domain; Region: GARS_C; pfam02843
699034001450	phosphoribosylformylglycinamidine synthase, clade II; Region: FGAM-synthase; TIGR01857
699034001451	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), first repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat1; cd02203
699034001452	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
699034001453	dimerization interface [polypeptide binding]; other site
699034001454	ATP binding site [chemical binding]; other site
699034001455	PurL subunit of the formylglycinamide ribonucleotide amidotransferase (FGAR-AT), second repeat. FGAR-AT catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to formylglycinamidine ribonucleotide (FGAM), ADP; Region: PurL_repeat2; cd02204
699034001456	dimerization interface [polypeptide binding]; other site
699034001457	ATP binding site [chemical binding]; other site
699034001458	CobB/CobQ-like glutamine amidotransferase domain; Region: GATase_5; pfam13507
699034001459	conserved cys residue [active]
699034001460	dTDP-4-dehydrorhamnose reductase [Cell envelope biogenesis, outer membrane]; Region: RfbD; COG1091
699034001461	dTDP-6-deoxy-L-lyxo-4-hexulose reductase and related proteins, extended (e) SDRs; Region: dTDP_HR_like_SDR_e; cd05254
699034001462	NADP binding site [chemical binding]; other site
699034001463	active site
699034001464	putative substrate binding site [chemical binding]; other site
699034001465	G1P_TT_short is the short form of glucose-1-phosphate thymidylyltransferase; Region: G1P_TT_short; cd02538
699034001466	glucose-1-phosphate thymidylyltransferase, short form; Region: rmlA; TIGR01207
699034001467	substrate binding site; other site
699034001468	tetramer interface; other site
699034001469	dTDP-4-dehydrorhamnose 3,5-epimerase; Region: dTDP_sugar_isom; pfam00908
699034001470	dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]; Region: RfbB; COG1088
699034001471	dTDP-D-glucose 4,6-dehydratase, extended (e) SDRs; Region: dTDP_GD_SDR_e; cd05246
699034001472	NAD binding site [chemical binding]; other site
699034001473	substrate binding site [chemical binding]; other site
699034001474	homodimer interface [polypeptide binding]; other site
699034001475	active site
699034001476	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
699034001477	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
699034001478	N-acetyl-D-glucosamine binding site [chemical binding]; other site
699034001479	catalytic residue [active]
699034001480	Protein of unknown function (DUF327); Region: DUF327; pfam03885
699034001481	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
699034001482	Anti-sigma-28 factor, FlgM; Region: FlgM; pfam04316
699034001483	FlgN protein; Region: FlgN; pfam05130
699034001484	flagellar hook-associated protein FlgK; Validated; Region: flgK; PRK07739
699034001485	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
699034001486	Protein of unknown function (DUF4038); Region: DUF4038; pfam13204
699034001487	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
699034001488	flagellar hook-associated protein FlgL; Validated; Region: flgL; PRK07701
699034001489	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
699034001490	FliW protein; Region: FliW; pfam02623
699034001491	Global regulator protein family; Region: CsrA; pfam02599
699034001492	Flagellar protein FliS; Region: FliS; cl00654
699034001493	Flagellar protein FliS; Region: FliS; cl00654
699034001494	flagellar capping protein; Validated; Region: fliD; PRK07737
699034001495	Flagellar hook-associated protein 2 N-terminus; Region: FliD_N; pfam02465
699034001496	Flagellar hook-associated protein 2 C-terminus; Region: FliD_C; pfam07195
699034001497	Flagellar protein FliT; Region: FliT; pfam05400
699034001498	flagellin; Reviewed; Region: PRK08869
699034001499	Bacterial flagellin N-terminal helical region; Region: Flagellin_N; pfam00669
699034001500	Bacterial flagellin C-terminal helical region; Region: Flagellin_C; pfam00700
699034001501	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
699034001502	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
699034001503	active site
699034001504	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
699034001505	binding surface
699034001506	TPR motif; other site
699034001507	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
699034001508	Subfamily of Glycosyltransferase Family GT2 of unknown function; Region: GT_2_like_c; cd04186
699034001509	Probable Catalytic site; other site
699034001510	metal-binding site
699034001511	Methyltransferase domain; Region: Methyltransf_31; pfam13847
699034001512	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
699034001513	S-adenosylmethionine binding site [chemical binding]; other site
699034001514	Glycosyltransferase like family; Region: Glyco_tranf_2_5; pfam13712
699034001515	Acetyltransferase (GNAT) domain; Region: Acetyltransf_6; pfam13480
699034001516	ATP-grasp domain; Region: ATP-grasp_4; pfam13535
699034001517	Predicted ornithine cyclodeaminase, mu-crystallin homolog [Amino acid transport and metabolism]; Region: COG2423
699034001518	Shikimate / quinate 5-dehydrogenase; Region: Shikimate_DH; cl19124
699034001519	WxcM-like, C-terminal; Region: FdtA; pfam05523
699034001520	3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary...; Region: AHBA_syn; cd00616
699034001521	inhibitor-cofactor binding pocket; inhibition site
699034001522	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034001523	catalytic residue [active]
699034001524	flagellar basal body rod protein FlgB; Provisional; Region: flgB; PRK12623
699034001525	flagellar basal body rod protein FlgB; Provisional; Region: flgB; cl19173
699034001526	flagellar basal body rod protein FlgC; Reviewed; Region: flgC; PRK05681
699034001527	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
699034001528	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
699034001529	flagellar hook-basal body protein FliE; Provisional; Region: fliE; PRK12728
699034001530	flagellar MS-ring protein; Reviewed; Region: fliF; PRK06007
699034001531	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907
699034001532	Flagellar M-ring protein C-terminal; Region: YscJ_FliF_C; pfam08345
699034001533	flagellar motor switch protein G; Validated; Region: fliG; PRK05686
699034001534	FliG N-terminal domain; Region: FliG_N; pfam14842
699034001535	FliG middle domain; Region: FliG_M; pfam14841
699034001536	FliG C-terminal domain; Region: FliG_C; pfam01706
699034001537	Protein of unknown function (DUF2799); Region: DUF2799; cl19633
699034001538	Flagellar biosynthesis/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliH; COG1317
699034001539	flagellar protein export ATPase FliI; Region: FliI_clade2; TIGR03497
699034001540	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
699034001541	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
699034001542	Walker A motif/ATP binding site; other site
699034001543	Walker B motif; other site
699034001544	flagellar export protein FliJ; Region: flagell_FliJ; TIGR02473
699034001545	Flagellar hook-length control protein FliK; Region: Flg_hook; pfam02120
699034001546	Flagellar hook capping protein - N-terminal region; Region: FlgD; pfam03963
699034001547	flagellar basal body rod modification protein; Reviewed; Region: flgD; PRK06009
699034001548	flagellar basal body rod protein FlgG; Provisional; Region: flgG; PRK12636
699034001549	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
699034001550	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
699034001551	Flagellar protein (FlbD); Region: FlbD; pfam06289
699034001552	MotA/TolQ/ExbB proton channel family; Region: MotA_ExbB; cl00568
699034001553	Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360
699034001554	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
699034001555	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
699034001556	ligand binding site [chemical binding]; other site
699034001557	Flagellar basal body-associated protein FliL; Region: FliL; pfam03748
699034001558	flagellar biosynthetic protein FliO; Region: FliO_TIGR; TIGR03500
699034001559	flagellar biosynthesis protein FliP; Reviewed; Region: fliP; PRK05699
699034001560	Flagellar biosynthesis pathway, component FliQ [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliQ; COG1987
699034001561	bifunctional flagellar biosynthesis protein FliR/FlhB; Provisional; Region: PRK12772
699034001562	flagellar biosynthesis protein FliR; Reviewed; Region: fliR; PRK05701
699034001563	flagellar biosynthesis protein FlhB; Reviewed; Region: flhB; PRK05702
699034001564	flagellar biosynthesis protein FlhA; Validated; Region: flhA; PRK06012
699034001565	flagellar biosynthesis regulator FlhF; Validated; Region: flhF; PRK05703
699034001566	SRP54-type protein, GTPase domain; Region: SRP54; smart00962
699034001567	Antiactivator of flagellar biosynthesis FleN, an ATPase [Cell motility]; Region: flhG; COG0455
699034001568	FleN is a member of the Fer4_NifH superfamily. It shares the common function as an ATPase, with the ATP-binding domain at the N-terminus. In Pseudomonas aeruginosa, FleN gene is involved in regulating the number of flagella and chemotactic motility by...; Region: FleN-like; cd02038
699034001569	P-loop; other site
699034001570	RNA polymerase sigma factor, FliA/WhiG family; Region: FliA_WhiG; TIGR02479
699034001571	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
699034001572	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
699034001573	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
699034001574	DNA binding residues [nucleotide binding]
699034001575	flagellar basal body rod protein FlgG; Reviewed; Region: flgG; PRK12818
699034001576	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
699034001577	flagellar basal-body rod protein FlgF; Region: flgF; TIGR02490
699034001578	flagellar basal body rod protein FlgG; Reviewed; Region: flgG; PRK12817
699034001579	Flagella basal body rod protein; Region: Flg_bb_rod; pfam00460
699034001580	Flagellar basal body rod FlgEFG protein C-terminal; Region: Flg_bbr_C; pfam06429
699034001581	Flagellar motor switch protein FliM; Region: FliM; pfam02154
699034001582	Surface presentation of antigens (SPOA); Region: SpoA; pfam01052
699034001583	Surface presentation of antigens (SPOA); Region: SpoA; cl00819
699034001584	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
699034001585	binding surface
699034001586	Tetratricopeptide repeat; Region: TPR_12; pfam13424
699034001587	TPR motif; other site
699034001588	heat shock protein 90; Provisional; Region: PRK05218
699034001589	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034001590	ATP binding site [chemical binding]; other site
699034001591	Mg2+ binding site [ion binding]; other site
699034001592	G-X-G motif; other site
699034001593	Hsp90 protein; Region: HSP90; pfam00183
699034001594	Iron-containing alcohol dehydrogenases-like; Region: Fe-ADH1; cd08185
699034001595	putative active site [active]
699034001596	metal binding site [ion binding]; metal-binding site
699034001597	DNA repair photolyase [DNA replication, recombination, and repair]; Region: SplB; COG1533
699034001598	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
699034001599	FeS/SAM binding site; other site
699034001600	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
699034001601	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
699034001602	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
699034001603	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
699034001604	Protein of unknown function (DUF3788); Region: DUF3788; pfam12663
699034001605	Predicted transcriptional regulators [Transcription]; Region: COG1733
699034001606	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
699034001607	putative hydrolase; Validated; Region: PRK09248
699034001608	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
699034001609	active site
699034001610	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
699034001611	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034001612	Walker A motif; other site
699034001613	ATP binding site [chemical binding]; other site
699034001614	Walker B motif; other site
699034001615	arginine finger; other site
699034001616	Transcriptional antiterminator [Transcription]; Region: COG3933
699034001617	PRD domain; Region: PRD; pfam00874
699034001618	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
699034001619	active pocket/dimerization site; other site
699034001620	active site
699034001621	phosphorylation site [posttranslational modification]
699034001622	PRD domain; Region: PRD; pfam00874
699034001623	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
699034001624	active pocket/dimerization site; other site
699034001625	active site
699034001626	phosphorylation site [posttranslational modification]
699034001627	PTS system sorbose subfamily IIB component; Region: PTSIIB_sorb; pfam03830
699034001628	active site
699034001629	phosphorylation site [posttranslational modification]
699034001630	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
699034001631	active pocket/dimerization site; other site
699034001632	active site
699034001633	phosphorylation site [posttranslational modification]
699034001634	PTS system sorbose subfamily IIB component; Region: PTSIIB_sorb; pfam03830
699034001635	active site
699034001636	phosphorylation site [posttranslational modification]
699034001637	PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609
699034001638	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
699034001639	L-2-amino-thiazoline-4-carboxylic acid hydrolase; Region: ATC_hydrolase; pfam14196
699034001640	dipeptidase PepV; Reviewed; Region: PRK07318
699034001641	M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides; Region: M20_PepV; cd03888
699034001642	active site
699034001643	metal binding site [ion binding]; metal-binding site
699034001644	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
699034001645	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034001646	non-specific DNA binding site [nucleotide binding]; other site
699034001647	salt bridge; other site
699034001648	sequence-specific DNA binding site [nucleotide binding]; other site
699034001649	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
699034001650	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
699034001651	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
699034001652	Walker A/P-loop; other site
699034001653	ATP binding site [chemical binding]; other site
699034001654	Q-loop/lid; other site
699034001655	ABC transporter signature motif; other site
699034001656	Walker B; other site
699034001657	D-loop; other site
699034001658	H-loop/switch region; other site
699034001659	Acyltransferase family; Region: Acyl_transf_3; cl19154
699034001660	Uncharacterized Fe-S center protein [General function prediction only]; Region: COG2768
699034001661	Domain of unknown function (DUF362); Region: DUF362; cl19822
699034001662	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
699034001663	biotin synthase; Region: bioB; TIGR00433
699034001664	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
699034001665	FeS/SAM binding site; other site
699034001666	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
699034001667	Transcriptional regulators [Transcription]; Region: PurR; COG1609
699034001668	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
699034001669	DNA binding site [nucleotide binding]
699034001670	domain linker motif; other site
699034001671	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
699034001672	dimerization interface [polypeptide binding]; other site
699034001673	ligand binding site [chemical binding]; other site
699034001674	Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides...; Region: ribokinase; cd01174
699034001675	substrate binding site [chemical binding]; other site
699034001676	dimer interface [polypeptide binding]; other site
699034001677	ATP binding site [chemical binding]; other site
699034001678	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
699034001679	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
699034001680	ligand binding site [chemical binding]; other site
699034001681	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
699034001682	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
699034001683	Walker A/P-loop; other site
699034001684	ATP binding site [chemical binding]; other site
699034001685	Q-loop/lid; other site
699034001686	ABC transporter signature motif; other site
699034001687	Walker B; other site
699034001688	D-loop; other site
699034001689	H-loop/switch region; other site
699034001690	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
699034001691	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
699034001692	TM-ABC transporter signature motif; other site
699034001693	acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase; Region: DapE-ArgE; TIGR01910
699034001694	Zinc peptidases M18, M20, M28, and M42; Region: Zinc_peptidase_like; cl14876
699034001695	metal binding site [ion binding]; metal-binding site
699034001696	A4 beta-galactosidase middle domain: a type 1 glutamine amidotransferase (GATase1)-like domain; Region: A4_beta-galactosidase_middle_domain; cd03143
699034001697	1,3-beta-galactosyl-N-acetylhexosamine phosphorylase; Region: TIGR02336
699034001698	M20 Peptidase Aminoacylase 1-like protein 2 aminobenzoyl-glutamate utilization protein B subfamily; Region: M20_Acy1L2_AbgB; cd05673
699034001699	putative metal binding site [ion binding]; other site
699034001700	Nitroreductase [Energy production and conversion]; Region: NfnB; COG0778
699034001701	FMN binding site [chemical binding]; other site
699034001702	dimer interface [polypeptide binding]; other site
699034001703	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
699034001704	Transcriptional regulator C-terminal region; Region: TetR_C_8; pfam14278
699034001705	potential frameshift: common BLAST hit: gi|170754594|ref|YP_001780490.1| acetyltransferase
699034001706	Tetratricopeptide repeat; Region: TPR_16; pfam13432
699034001707	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
699034001708	haloacid dehalogenase-like hydrolase; Region: Hydrolase; pfam00702
699034001709	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
699034001710	dimerization interface [polypeptide binding]; other site
699034001711	putative DNA binding site [nucleotide binding]; other site
699034001712	putative Zn2+ binding site [ion binding]; other site
699034001713	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
699034001714	metal-binding site [ion binding]
699034001715	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
699034001716	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
699034001717	metal-binding site [ion binding]
699034001718	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
699034001719	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
699034001720	potential RNA of insufficient length (23S ribosomal RNA)
699034001721	Uncharacterized membrane-associated protein [Function unknown]; Region: DedA; COG0586
699034001722	SNARE associated Golgi protein; Region: SNARE_assoc; pfam09335
699034001723	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
699034001724	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
699034001725	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
699034001726	ATP-binding cassette domain of the bacitracin-resistance transporter; Region: ABC_BcrA_bacitracin_resist; cd03268
699034001727	Walker A/P-loop; other site
699034001728	ATP binding site [chemical binding]; other site
699034001729	Q-loop/lid; other site
699034001730	ABC transporter signature motif; other site
699034001731	Walker B; other site
699034001732	D-loop; other site
699034001733	H-loop/switch region; other site
699034001734	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034001735	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034001736	dimer interface [polypeptide binding]; other site
699034001737	phosphorylation site [posttranslational modification]
699034001738	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034001739	ATP binding site [chemical binding]; other site
699034001740	Mg2+ binding site [ion binding]; other site
699034001741	G-X-G motif; other site
699034001742	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034001743	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034001744	active site
699034001745	phosphorylation site [posttranslational modification]
699034001746	intermolecular recognition site; other site
699034001747	dimerization interface [polypeptide binding]; other site
699034001748	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034001749	DNA binding site [nucleotide binding]
699034001750	Helix-turn-helix domain; Region: HTH_17; pfam12728
699034001751	MoxR-like ATPases [General function prediction only]; Region: COG0714
699034001752	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl18944
699034001753	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cl00057
699034001754	metal ion-dependent adhesion site (MIDAS); other site
699034001755	cobalt transport protein CbiM; Validated; Region: PRK08319
699034001756	cobalt transport protein CbiN; Provisional; Region: PRK02898
699034001757	Cobalt transport protein; Region: CbiQ; cl00463
699034001758	ABC-type cobalt transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CbiO; COG1122
699034001759	First domain of the ATP-binding cassette component of cobalt transport system; Region: ABC_cobalt_CbiO_domain1; cd03225
699034001760	Walker A/P-loop; other site
699034001761	ATP binding site [chemical binding]; other site
699034001762	Q-loop/lid; other site
699034001763	ABC transporter signature motif; other site
699034001764	Walker B; other site
699034001765	D-loop; other site
699034001766	H-loop/switch region; other site
699034001767	ATP-dependent DNA helicase PcrA; Region: pcrA; TIGR01073
699034001768	Part of AAA domain; Region: AAA_19; pfam13245
699034001769	Family description; Region: UvrD_C_2; pfam13538
699034001770	M18 Peptidase Aspartyl aminopeptidase; Region: M18_DAP; cd05658
699034001771	active site
699034001772	metal binding site [ion binding]; metal-binding site
699034001773	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
699034001774	active site
699034001775	nucleophile elbow; other site
699034001776	cyclophilin: cyclophilin-type peptidylprolyl cis- trans isomerases. This family contains eukaryotic, bacterial and archeal proteins which exhibit a peptidylprolyl cis- trans isomerases activity (PPIase, Rotamase) and in addition bind the...; Region: cyclophilin; cd00317
699034001777	active site
699034001778	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
699034001779	putative manganese-dependent inorganic pyrophosphatase; Provisional; Region: PRK14869
699034001780	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with a DRTGG domain upstream. The function of the DRTGG domain, named after its conserved residues, is unknown. CBS is a small domain originally...; Region: CBS_pair_DRTGG_assoc2; cd04597
699034001781	DRTGG domain; Region: DRTGG; pfam07085
699034001782	CBS domain; Region: CBS; pfam00571
699034001783	DHHA2 domain; Region: DHHA2; pfam02833
699034001784	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
699034001785	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
699034001786	putative catalytic cysteine [active]
699034001787	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
699034001788	putative active site [active]
699034001789	metal binding site [ion binding]; metal-binding site
699034001790	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
699034001791	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
699034001792	Walker A/P-loop; other site
699034001793	ATP binding site [chemical binding]; other site
699034001794	Q-loop/lid; other site
699034001795	ABC transporter signature motif; other site
699034001796	Walker B; other site
699034001797	D-loop; other site
699034001798	H-loop/switch region; other site
699034001799	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
699034001800	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
699034001801	FtsX-like permease family; Region: FtsX; pfam02687
699034001802	FtsX-like permease family; Region: FtsX; pfam02687
699034001803	Sensor_kinase_SpoOB-type, alpha-helical domain; Region: SPOB_a; pfam14689
699034001804	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034001805	ATP binding site [chemical binding]; other site
699034001806	Mg2+ binding site [ion binding]; other site
699034001807	G-X-G motif; other site
699034001808	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
699034001809	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034001810	active site
699034001811	phosphorylation site [posttranslational modification]
699034001812	intermolecular recognition site; other site
699034001813	dimerization interface [polypeptide binding]; other site
699034001814	LytTr DNA-binding domain; Region: LytTR; pfam04397
699034001815	Domain of unknown function (DUF4132); Region: DUF4132; pfam13569
699034001816	Putative zinc- or iron-chelating domain; Region: CxxCxxCC; pfam03692
699034001817	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
699034001818	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
699034001819	synthetase active site [active]
699034001820	NTP binding site [chemical binding]; other site
699034001821	metal binding site [ion binding]; metal-binding site
699034001822	Predicted phosphohydrolase [General function prediction only]; Region: COG1768
699034001823	Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409
699034001824	AAA ATPase containing von Willebrand factor type A (vWA) domain [General function prediction only]; Region: MDN1; COG5271
699034001825	Methyltransferase domain; Region: Methyltransf_31; pfam13847
699034001826	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
699034001827	S-adenosylmethionine binding site [chemical binding]; other site
699034001828	Uncharacterized conserved protein [Function unknown]; Region: COG5663
699034001829	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
699034001830	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034001831	non-specific DNA binding site [nucleotide binding]; other site
699034001832	salt bridge; other site
699034001833	sequence-specific DNA binding site [nucleotide binding]; other site
699034001834	Cupin domain; Region: Cupin_2; pfam07883
699034001835	D-aminoacyl-tRNA deacylase; Region: tRNA_deacylase; cl00716
699034001836	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
699034001837	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
699034001838	active site turn [active]
699034001839	phosphorylation site [posttranslational modification]
699034001840	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
699034001841	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
699034001842	HPr interaction site; other site
699034001843	glycerol kinase (GK) interaction site [polypeptide binding]; other site
699034001844	active site
699034001845	phosphorylation site [posttranslational modification]
699034001846	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; cl01046
699034001847	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; pfam00232
699034001848	transcriptional antiterminator BglG; Provisional; Region: PRK09772
699034001849	CAT RNA binding domain; Region: CAT_RBD; smart01061
699034001850	PRD domain; Region: PRD; pfam00874
699034001851	PRD domain; Region: PRD; pfam00874
699034001852	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
699034001853	active site
699034001854	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
699034001855	Ligand Binding Site [chemical binding]; other site
699034001856	Molecular Tunnel; other site
699034001857	Predicted Fe-S oxidoreductases [General function prediction only]; Region: COG0535
699034001858	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
699034001859	FeS/SAM binding site; other site
699034001860	TIGR04002 family protein; Region: TIGR04002
699034001861	D-lactate dehydrogenase; Validated; Region: PRK08605
699034001862	D-Lactate dehydrogenase and D-2-Hydroxyisocaproic acid dehydrogenase (D-HicDH), NAD-binding and catalytic domains; Region: LDH; cd12186
699034001863	homodimer interface [polypeptide binding]; other site
699034001864	ligand binding site [chemical binding]; other site
699034001865	NAD binding site [chemical binding]; other site
699034001866	catalytic site [active]
699034001867	Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804
699034001868	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
699034001869	benzoyl-CoA reductase, bcr type, subunit B; Region: benz_CoA_red_B; TIGR02260
699034001870	2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050
699034001871	Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB [Amino acid transport and metabolism]; Region: HgdB; COG1775
699034001872	2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050
699034001873	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
699034001874	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
699034001875	active site
699034001876	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
699034001877	Ligand binding site [chemical binding]; other site
699034001878	Electron transfer flavoprotein domain; Region: ETF; pfam01012
699034001879	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
699034001880	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
699034001881	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
699034001882	PAS domain; Region: PAS; smart00091
699034001883	PAS domain; Region: PAS_9; pfam13426
699034001884	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
699034001885	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034001886	Walker A motif; other site
699034001887	ATP binding site [chemical binding]; other site
699034001888	Walker B motif; other site
699034001889	arginine finger; other site
699034001890	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
699034001891	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
699034001892	intersubunit interface [polypeptide binding]; other site
699034001893	active site
699034001894	zinc binding site [ion binding]; other site
699034001895	Na+ binding site [ion binding]; other site
699034001896	Domain of unknown function (DUF1904); Region: DUF1904; pfam08921
699034001897	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
699034001898	RNA binding surface [nucleotide binding]; other site
699034001899	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
699034001900	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
699034001901	Probable transposase; Region: OrfB_IS605; pfam01385
699034001902	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
699034001903	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
699034001904	Pseudouridine synthase, Escherichia coli RsuA like; Region: PseudoU_synth_RsuA; cd02553
699034001905	active site
699034001906	uracil binding [chemical binding]; other site
699034001907	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
699034001908	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
699034001909	S-adenosylmethionine binding site [chemical binding]; other site
699034001910	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
699034001911	Protein of unknown function (DUF4236); Region: DUF4236; pfam14020
699034001912	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034001913	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034001914	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034001915	putative transposase OrfB; Reviewed; Region: PHA02517
699034001916	HTH-like domain; Region: HTH_21; pfam13276
699034001917	Integrase core domain; Region: rve; pfam00665
699034001918	Integrase core domain; Region: rve_2; pfam13333
699034001919	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
699034001920	Helix-turn-helix domain; Region: HTH_28; pfam13518
699034001921	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
699034001922	Helix-turn-helix domain; Region: HTH_28; pfam13518
699034001923	PAS domain; Region: PAS_9; pfam13426
699034001924	psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974
699034001925	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034001926	Walker A motif; other site
699034001927	ATP binding site [chemical binding]; other site
699034001928	Walker B motif; other site
699034001929	arginine finger; other site
699034001930	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
699034001931	Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown]; Region: COG3804
699034001932	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; cl19130
699034001933	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640
699034001934	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
699034001935	catalytic residue [active]
699034001936	D-Lysine 5,6-aminomutase alpha subunit; Region: Lys-AminoMut_A; pfam09043
699034001937	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
699034001938	B12 binding site [chemical binding]; other site
699034001939	MutL protein; Region: MutL; pfam13941
699034001940	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase-like 1; Region: PLPDE_III_AR_like_1; cd06815
699034001941	Predicted amino acid racemase [Amino acid transport and metabolism]; Region: COG3457
699034001942	dimer interface [polypeptide binding]; other site
699034001943	active site
699034001944	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
699034001945	substrate binding site [chemical binding]; other site
699034001946	catalytic residue [active]
699034001947	Na+/H+ antiporter NhaC; Region: antiport_nhaC; TIGR00931
699034001948	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
699034001949	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
699034001950	active site
699034001951	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
699034001952	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
699034001953	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
699034001954	Superfamily I DNA and RNA helicases [General function prediction only]; Region: COG3973
699034001955	Part of AAA domain; Region: AAA_19; pfam13245
699034001956	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538
699034001957	Excinuclease ATPase subunit [DNA replication, recombination, and repair]; Region: UvrA; COG0178
699034001958	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
699034001959	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034001960	Walker A/P-loop; other site
699034001961	ATP binding site [chemical binding]; other site
699034001962	Q-loop/lid; other site
699034001963	ABC transporter signature motif; other site
699034001964	Walker B; other site
699034001965	D-loop; other site
699034001966	H-loop/switch region; other site
699034001967	Beta-lactamase class D [Defense mechanisms]; Region: COG2602
699034001968	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
699034001969	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
699034001970	Walker A/P-loop; other site
699034001971	ATP binding site [chemical binding]; other site
699034001972	Q-loop/lid; other site
699034001973	ABC transporter signature motif; other site
699034001974	Walker B; other site
699034001975	D-loop; other site
699034001976	H-loop/switch region; other site
699034001977	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
699034001978	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
699034001979	FtsX-like permease family; Region: FtsX; pfam02687
699034001980	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
699034001981	FtsX-like permease family; Region: FtsX; pfam02687
699034001982	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034001983	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034001984	dimer interface [polypeptide binding]; other site
699034001985	phosphorylation site [posttranslational modification]
699034001986	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034001987	ATP binding site [chemical binding]; other site
699034001988	Mg2+ binding site [ion binding]; other site
699034001989	G-X-G motif; other site
699034001990	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034001991	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034001992	active site
699034001993	dimerization interface [polypeptide binding]; other site
699034001994	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034001995	DNA binding site [nucleotide binding]
699034001996	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
699034001997	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
699034001998	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
699034001999	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
699034002000	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
699034002001	Probable transposase; Region: OrfB_IS605; pfam01385
699034002002	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
699034002003	Transposase IS200 like; Region: Y1_Tnp; cl00848
699034002004	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
699034002005	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
699034002006	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
699034002007	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
699034002008	putative active site [active]
699034002009	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
699034002010	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
699034002011	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
699034002012	putative active site [active]
699034002013	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
699034002014	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
699034002015	active site
699034002016	motif I; other site
699034002017	motif II; other site
699034002018	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
699034002019	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
699034002020	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
699034002021	Ca binding site [ion binding]; other site
699034002022	active site
699034002023	catalytic site [active]
699034002024	PTS system, sucrose-specific IIBC component; Region: PTS-II-BC-sucr; TIGR01996
699034002025	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
699034002026	active site turn [active]
699034002027	phosphorylation site [posttranslational modification]
699034002028	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
699034002029	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
699034002030	HPr interaction site; other site
699034002031	glycerol kinase (GK) interaction site [polypeptide binding]; other site
699034002032	active site
699034002033	phosphorylation site [posttranslational modification]
699034002034	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
699034002035	Beta-lactamase class D [Defense mechanisms]; Region: COG2602
699034002036	Penicillinase repressor; Region: Penicillinase_R; pfam03965
699034002037	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
699034002038	Transcriptional regulators [Transcription]; Region: MarR; COG1846
699034002039	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
699034002040	Flavodoxins [Energy production and conversion]; Region: FldA; COG0716
699034002041	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
699034002042	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
699034002043	Uracil-DNA glycosylases (UDG) and related enzymes; Region: UDG_like; cl00483
699034002044	gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Region: galliderm_ABC; TIGR03740
699034002045	ATP-binding cassette domain of the bacitracin-resistance transporter; Region: ABC_BcrA_bacitracin_resist; cd03268
699034002046	Walker A/P-loop; other site
699034002047	ATP binding site [chemical binding]; other site
699034002048	Q-loop/lid; other site
699034002049	ABC transporter signature motif; other site
699034002050	Walker B; other site
699034002051	D-loop; other site
699034002052	H-loop/switch region; other site
699034002053	lantibiotic protection ABC transporter permease subunit, MutE/EpiE family; Region: lanti_perm_MutE; TIGR03732
699034002054	lantibiotic protection ABC transporter permease subunit, MutG family; Region: lanti_perm_MutG; TIGR03733
699034002055	proteobacterial dedicated sortase system response regulator; Region: marine_sort_RR; TIGR03787
699034002056	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034002057	active site
699034002058	phosphorylation site [posttranslational modification]
699034002059	intermolecular recognition site; other site
699034002060	dimerization interface [polypeptide binding]; other site
699034002061	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034002062	DNA binding site [nucleotide binding]
699034002063	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034002064	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
699034002065	dimerization interface [polypeptide binding]; other site
699034002066	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034002067	dimer interface [polypeptide binding]; other site
699034002068	phosphorylation site [posttranslational modification]
699034002069	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034002070	ATP binding site [chemical binding]; other site
699034002071	Mg2+ binding site [ion binding]; other site
699034002072	G-X-G motif; other site
699034002073	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
699034002074	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
699034002075	FtsX-like permease family; Region: FtsX; pfam02687
699034002076	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
699034002077	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
699034002078	FtsX-like permease family; Region: FtsX; pfam02687
699034002079	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
699034002080	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
699034002081	Walker A/P-loop; other site
699034002082	ATP binding site [chemical binding]; other site
699034002083	Q-loop/lid; other site
699034002084	ABC transporter signature motif; other site
699034002085	Walker B; other site
699034002086	D-loop; other site
699034002087	H-loop/switch region; other site
699034002088	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
699034002089	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034002090	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
699034002091	dimerization interface [polypeptide binding]; other site
699034002092	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034002093	dimer interface [polypeptide binding]; other site
699034002094	phosphorylation site [posttranslational modification]
699034002095	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034002096	ATP binding site [chemical binding]; other site
699034002097	Mg2+ binding site [ion binding]; other site
699034002098	G-X-G motif; other site
699034002099	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034002100	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034002101	active site
699034002102	phosphorylation site [posttranslational modification]
699034002103	intermolecular recognition site; other site
699034002104	dimerization interface [polypeptide binding]; other site
699034002105	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034002106	DNA binding site [nucleotide binding]
699034002107	Nit1, Nit 2, and related proteins, and the Nit1-like domain of NitFhit (class 10 nitrilases); Region: nit; cd07572
699034002108	putative active site [active]
699034002109	catalytic triad [active]
699034002110	dimer interface [polypeptide binding]; other site
699034002111	Membrane transporters of cations and cationic drugs [Inorganic ion transport and metabolism]; Region: EmrE; COG2076
699034002112	5-aminoimidazole-4-(N-succinylcarboxamide) ribonucleotide (SAICAR) synthase; Region: SAICAR_synt; cl00231
699034002113	ATP binding site [chemical binding]; other site
699034002114	active site
699034002115	substrate binding site [chemical binding]; other site
699034002116	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
699034002117	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
699034002118	putative NAD(P) binding site [chemical binding]; other site
699034002119	catalytic Zn binding site [ion binding]; other site
699034002120	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
699034002121	active pocket/dimerization site; other site
699034002122	active site
699034002123	phosphorylation site [posttranslational modification]
699034002124	PTS system sorbose subfamily IIB component; Region: PTSIIB_sorb; pfam03830
699034002125	active site
699034002126	phosphorylation site [posttranslational modification]
699034002127	PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609
699034002128	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
699034002129	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034002130	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034002131	active site
699034002132	phosphorylation site [posttranslational modification]
699034002133	intermolecular recognition site; other site
699034002134	dimerization interface [polypeptide binding]; other site
699034002135	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034002136	DNA binding site [nucleotide binding]
699034002137	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034002138	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
699034002139	dimerization interface [polypeptide binding]; other site
699034002140	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034002141	dimer interface [polypeptide binding]; other site
699034002142	phosphorylation site [posttranslational modification]
699034002143	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034002144	ATP binding site [chemical binding]; other site
699034002145	Mg2+ binding site [ion binding]; other site
699034002146	G-X-G motif; other site
699034002147	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034002148	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034002149	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034002150	flagellin; Validated; Region: PRK08026
699034002151	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
699034002152	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl19191
699034002153	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
699034002154	Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain [Transcription / Signal transduction mechanisms]; Region: PspF; COG1221
699034002155	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034002156	Walker A motif; other site
699034002157	ATP binding site [chemical binding]; other site
699034002158	Walker B motif; other site
699034002159	arginine finger; other site
699034002160	Transcriptional antiterminator [Transcription]; Region: COG3933
699034002161	PRD domain; Region: PRD; pfam00874
699034002162	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
699034002163	active pocket/dimerization site; other site
699034002164	active site
699034002165	phosphorylation site [posttranslational modification]
699034002166	PRD domain; Region: PRD; pfam00874
699034002167	Uncharacterized conserved protein [Function unknown]; Region: COG2966
699034002168	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
699034002169	Protein of unknown function (DUF3815); Region: DUF3815; pfam12821
699034002170	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
699034002171	GAF domain; Region: GAF_3; pfam13492
699034002172	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034002173	dimer interface [polypeptide binding]; other site
699034002174	phosphorylation site [posttranslational modification]
699034002175	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034002176	ATP binding site [chemical binding]; other site
699034002177	Mg2+ binding site [ion binding]; other site
699034002178	G-X-G motif; other site
699034002179	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034002180	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034002181	active site
699034002182	phosphorylation site [posttranslational modification]
699034002183	intermolecular recognition site; other site
699034002184	dimerization interface [polypeptide binding]; other site
699034002185	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034002186	DNA binding site [nucleotide binding]
699034002187	GAF domain; Region: GAF_2; pfam13185
699034002188	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
699034002189	metal binding site [ion binding]; metal-binding site
699034002190	active site
699034002191	I-site; other site
699034002192	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
699034002193	metal binding site [ion binding]; metal-binding site
699034002194	active site
699034002195	I-site; other site
699034002196	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
699034002197	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
699034002198	M20 Peptidase T like enzymes specifically cleave tripeptides; Region: M20_peptT_like; cd05683
699034002199	peptidase T-like protein; Region: PepT-like; TIGR01883
699034002200	metal binding site [ion binding]; metal-binding site
699034002201	putative dimer interface [polypeptide binding]; other site
699034002202	Putative p-aminobenzoyl-glutamate transporter [Coenzyme metabolism]; Region: AbgT; COG2978
699034002203	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
699034002204	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
699034002205	M20 Peptidase Aminoacylase 1-like protein 2, amidohydrolase family; Region: M20_Acy1L2_like_2; cd09849
699034002206	metal binding site [ion binding]; metal-binding site
699034002207	Protein of unknown function (DUF3100); Region: DUF3100; pfam11299
699034002208	Predicted transcriptional regulator [Transcription]; Region: COG2378
699034002209	HTH domain; Region: HTH_11; pfam08279
699034002210	WYL domain; Region: WYL; pfam13280
699034002211	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
699034002212	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034002213	active site
699034002214	phosphorylation site [posttranslational modification]
699034002215	intermolecular recognition site; other site
699034002216	dimerization interface [polypeptide binding]; other site
699034002217	Chemotaxis protein CheC, inhibitor of MCP methylation [Cell motility and secretion / Signal transduction mechanisms]; Region: CheC; COG1776
699034002218	CheC-like family; Region: CheC; pfam04509
699034002219	CheD chemotactic sensory transduction; Region: CheD; cl00810
699034002220	Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms]; Region: CheW; COG0835
699034002221	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034002222	active site
699034002223	phosphorylation site [posttranslational modification]
699034002224	intermolecular recognition site; other site
699034002225	dimerization interface [polypeptide binding]; other site
699034002226	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
699034002227	metal binding site [ion binding]; metal-binding site
699034002228	active site
699034002229	I-site; other site
699034002230	ligand binding domain of Tar- and Tsr-related chemoreceptors; Region: Tar_Tsr_LBD; cl00144
699034002231	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
699034002232	dimerization interface [polypeptide binding]; other site
699034002233	Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Region: MA; smart00283
699034002234	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cl19050
699034002235	dimer interface [polypeptide binding]; other site
699034002236	putative CheW interface [polypeptide binding]; other site
699034002237	Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms]; Region: CheA; COG0643
699034002238	Histidine Phosphotransfer domain, involved in signalling through a two part component systems in which an autophosphorylating histidine protein kinase serves as a phosphoryl donor to a response regulator protein; the response regulator protein is...; Region: HPT; cd00088
699034002239	putative binding surface; other site
699034002240	active site
699034002241	P2 response regulator binding domain; Region: P2; pfam07194
699034002242	Signal transducing histidine kinase, homodimeric domain; Region: H-kinase_dim; pfam02895
699034002243	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034002244	ATP binding site [chemical binding]; other site
699034002245	Mg2+ binding site [ion binding]; other site
699034002246	G-X-G motif; other site
699034002247	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cl00256
699034002248	CheW-like domain. CheW proteins are part of the chemotaxis signalling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and...; Region: CheW_like; cl00256
699034002249	CheR methyltransferase, all-alpha domain; Region: CheR_N; pfam03705
699034002250	Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms]; Region: CheR; COG1352
699034002251	CheR methyltransferase, SAM binding domain; Region: CheR; pfam01739
699034002252	CheB methylesterase; Region: CheB_methylest; pfam01339
699034002253	Domain of unknown function (DUF4163); Region: DUF4163; pfam13739
699034002254	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
699034002255	ornithine cyclodeaminase; Validated; Region: PRK08618
699034002256	Shikimate / quinate 5-dehydrogenase; Region: Shikimate_DH; cl19124
699034002257	Protein of unknown function (DUF975); Region: DUF975; cl10504
699034002258	Penicillinase repressor; Region: Penicillinase_R; pfam03965
699034002259	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
699034002260	Formin Homology 2 Domain; Region: FH2; cl19758
699034002261	Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane]; Region: COG3409
699034002262	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
699034002263	Protease prsW family; Region: PrsW-protease; pfam13367
699034002264	rRNA (cytosine-C(5)-)-methyltransferase RsmF; Reviewed; Region: yebU; PRK11933
699034002265	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
699034002266	S-adenosylmethionine binding site [chemical binding]; other site
699034002267	pre-rRNA processing and ribosome biogenesis; Region: Nol1_Nop2_Fmu_2; pfam13636
699034002268	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
699034002269	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
699034002270	Catalytic site [active]
699034002271	The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the...; Region: Peptidase_S24_S26; cl10465
699034002272	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
699034002273	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
699034002274	Catalytic site [active]
699034002275	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
699034002276	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
699034002277	Uridine monophosphate kinase_like (UMPK_like) is a family of proteins highly similar to the uridine monophosphate kinase (UMPK, EC 2.7.1.48), also known as uridine kinase or uridine-cytidine kinase (UCK); Region: UMPK_like; cd02028
699034002278	active site
699034002279	glutaminase A; Region: Gln_ase; TIGR03814
699034002280	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
699034002281	dimerization interface [polypeptide binding]; other site
699034002282	putative DNA binding site [nucleotide binding]; other site
699034002283	putative Zn2+ binding site [ion binding]; other site
699034002284	Endonuclease IV [DNA replication, recombination, and repair]; Region: Nfo; COG0648
699034002285	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
699034002286	AP (apurinic/apyrimidinic) site pocket; other site
699034002287	DNA interaction; other site
699034002288	Metal-binding active site; metal-binding site
699034002289	Predicted oxidoreductases of the aldo/keto reductase family [General function prediction only]; Region: COG1453
699034002290	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
699034002291	active site
699034002292	catalytic tetrad [active]
699034002293	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
699034002294	Endodeoxyribonuclease RusA; Region: RusA; pfam05866
699034002295	Uncharacterized Fe-S protein [Energy production and conversion]; Region: COG1600
699034002296	Domain of unknown function (DUF1730); Region: DUF1730; pfam08331
699034002297	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
699034002298	AAA domain; Region: AAA_32; pfam13654
699034002299	lon-related putative ATP-dependent protease; Region: lon_rel; TIGR00764
699034002300	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
699034002301	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
699034002302	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
699034002303	minor groove reading motif; other site
699034002304	helix-hairpin-helix signature motif; other site
699034002305	substrate binding pocket [chemical binding]; other site
699034002306	active site
699034002307	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
699034002308	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
699034002309	EDD domain protein, DegV family; Region: DegV; TIGR00762
699034002310	Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea; Region: PBP1_BmpA_PnrA_like; cd06354
699034002311	ligand binding site [chemical binding]; other site
699034002312	Periplasmic binding domain of basic membrane lipoprotein, PnrA, in Treponema pallidum and its homologs from other bacteria and Archaea; Region: PBP1_BmpA_PnrA_like; cd06354
699034002313	ligand binding site [chemical binding]; other site
699034002314	YtxC-like family; Region: YtxC; cl08500
699034002315	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4399; cl19827
699034002316	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
699034002317	TGS _ThrRS_N:  ThrRS (threonyl-tRNA Synthetase)  is a class II tRNA synthetase that couples threonine to its cognate tRNA.  In addition to its catalytic and anticodon-binding domains, ThrRS has an N-terminal TGS domain, named after the ThrRS, GTPase, and...; Region: TGS_ThrRS_N; cd01667
699034002318	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
699034002319	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
699034002320	active site
699034002321	dimer interface [polypeptide binding]; other site
699034002322	motif 1; other site
699034002323	motif 2; other site
699034002324	motif 3; other site
699034002325	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
699034002326	anticodon binding site; other site
699034002327	Transposase IS200 like; Region: Y1_Tnp; cl00848
699034002328	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
699034002329	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
699034002330	Probable transposase; Region: OrfB_IS605; pfam01385
699034002331	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
699034002332	PD-(D/E)XK nuclease family transposase; Region: PDDEXK_2; pfam12784
699034002333	Domain of unknown function (DUF4098); Region: DUF4098; cl19992
699034002334	Protein of unknown function (DUF2807); Region: DUF2807; pfam10988
699034002335	Domain of unknown function (DUF4098); Region: DUF4098; pfam13345
699034002336	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
699034002337	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034002338	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034002339	ATP binding site [chemical binding]; other site
699034002340	Mg2+ binding site [ion binding]; other site
699034002341	G-X-G motif; other site
699034002342	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cl17215
699034002343	H+ Antiporter protein; Region: 2A0121; TIGR00900
699034002344	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
699034002345	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
699034002346	NADP+-dependent non-phosphorylating glyceraldehyde 3-phosphate dehydrogenase and ALDH family 11; Region: ALDH_F11_NP-GAPDH; cd07082
699034002347	tetrameric interface [polypeptide binding]; other site
699034002348	activator binding site; other site
699034002349	NADP binding site [chemical binding]; other site
699034002350	substrate binding site [chemical binding]; other site
699034002351	catalytic residues [active]
699034002352	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
699034002353	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
699034002354	phosphoenolpyruvate synthase; Validated; Region: PRK06241
699034002355	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
699034002356	PEP-utilizing enzyme, mobile domain; Region: PEP-utilizers; pfam00391
699034002357	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
699034002358	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034002359	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034002360	Walker A/P-loop; other site
699034002361	Walker A/P-loop; other site
699034002362	ATP binding site [chemical binding]; other site
699034002363	ATP binding site [chemical binding]; other site
699034002364	Q-loop/lid; other site
699034002365	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
699034002366	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
699034002367	Probable transposase; Region: OrfB_IS605; pfam01385
699034002368	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
699034002369	Circularly permuted YlqF-related GTPases; Region: YlqF_related_GTPase; cl17249
699034002370	G1 box; other site
699034002371	GTP/Mg2+ binding site [chemical binding]; other site
699034002372	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: SbcC; COG0419
699034002373	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
699034002374	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
699034002375	Soluble P-type ATPase [General function prediction only]; Region: COG4087
699034002376	Protein of unknown function (DUF3788); Region: DUF3788; pfam12663
699034002377	Predicted phosphoadenosine phosphosulfate sulfotransferase [General function prediction only]; Region: COG3969
699034002378	This domain is found in phosphoadenosine phosphosulphate (PAPS) reductase enzymes or PAPS sulphotransferase. PAPS reductase is part of the adenine nucleotide alpha hydrolases superfamily also including N type ATP PPases and ATP sulphurylases. A highly...; Region: PAPS_reductase; cd01713
699034002379	Active Sites [active]
699034002380	Domain of unknown function (DUF3440); Region: DUF3440; pfam11922
699034002381	Stage 0 sporulation protein J (antagonist of Soj) containing ParB-like nuclease domain [Transcription]; Region: Spo0J; COG1475
699034002382	ParB-like nuclease domain; Region: ParBc; pfam02195
699034002383	Spore coat associated protein JA (CotJA); Region: CotJA; pfam11007
699034002384	CotJB protein; Region: CotJB; pfam12652
699034002385	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
699034002386	dimanganese center [ion binding]; other site
699034002387	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
699034002388	6-O-methylguanine DNA methyltransferase, ribonuclease-like domain; Region: Methyltransf_1N; pfam02870
699034002389	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
699034002390	DNA binding site [nucleotide binding]
699034002391	active site
699034002392	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
699034002393	IncA protein; Region: IncA; pfam04156
699034002394	Protein of unknown function (DUF3795); Region: DUF3795; pfam12675
699034002395	GrpB protein; Region: GrpB; pfam04229
699034002396	Chloride channel protein EriC [Inorganic ion transport and metabolism]; Region: EriC; COG0038
699034002397	ClC chloride channel EriC.  This domain is found in the EriC chloride transporters that mediate the extreme acid resistance response in eubacteria and archaea. This response allows bacteria to survive in the acidic environments by decarboxylation-linked...; Region: EriC; cd01031
699034002398	Cl- selectivity filter; other site
699034002399	Cl- binding residues [ion binding]; other site
699034002400	pore gating glutamate residue; other site
699034002401	H+/Cl- coupling transport residue; other site
699034002402	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
699034002403	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
699034002404	Probable transposase; Region: OrfB_IS605; pfam01385
699034002405	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
699034002406	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cl02915
699034002407	dimer interface [polypeptide binding]; other site
699034002408	TrkA-C domain; Region: TrkA_C; pfam02080
699034002409	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
699034002410	GrpB protein; Region: GrpB; pfam04229
699034002411	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
699034002412	Sensor_kinase_SpoOB-type, alpha-helical domain; Region: SPOB_a; pfam14689
699034002413	GHKL domain; Region: HATPase_c_5; pfam14501
699034002414	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
699034002415	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034002416	active site
699034002417	phosphorylation site [posttranslational modification]
699034002418	intermolecular recognition site; other site
699034002419	dimerization interface [polypeptide binding]; other site
699034002420	LytTr DNA-binding domain; Region: LytTR; smart00850
699034002421	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
699034002422	FtsX-like permease family; Region: FtsX; pfam02687
699034002423	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
699034002424	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
699034002425	Walker A/P-loop; other site
699034002426	ATP binding site [chemical binding]; other site
699034002427	Q-loop/lid; other site
699034002428	ABC transporter signature motif; other site
699034002429	Walker B; other site
699034002430	D-loop; other site
699034002431	H-loop/switch region; other site
699034002432	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
699034002433	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
699034002434	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
699034002435	Helix-Turn-Helix DNA binding domain of the BmrR transcription regulator; Region: HTH_BmrR; cd01107
699034002436	DNA binding residues [nucleotide binding]
699034002437	drug binding residues [chemical binding]; other site
699034002438	dimer interface [polypeptide binding]; other site
699034002439	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
699034002440	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
699034002441	LytTr DNA-binding domain; Region: LytTR; smart00850
699034002442	YvrJ protein family; Region: YvrJ; pfam12841
699034002443	Protein of unknown function (DUF2922); Region: DUF2922; pfam11148
699034002444	Translocation protein Sec62; Region: Sec62; cl02170
699034002445	Protein of unknown function (DUF1659); Region: DUF1659; pfam07872
699034002446	Mor transcription activator family; Region: Mor; cl02360
699034002447	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
699034002448	non-specific DNA interactions [nucleotide binding]; other site
699034002449	DNA binding site [nucleotide binding]
699034002450	sequence specific DNA binding site [nucleotide binding]; other site
699034002451	putative cAMP binding site [chemical binding]; other site
699034002452	Conserved phage C-terminus (Phg_2220_C); Region: Phg_2220_C; pfam09524
699034002453	replicative DNA helicase; Region: DnaB; TIGR00665
699034002454	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
699034002455	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
699034002456	Walker A motif; other site
699034002457	ATP binding site [chemical binding]; other site
699034002458	Walker B motif; other site
699034002459	Mor transcription activator family; Region: Mor; cl02360
699034002460	Ferredoxin [Energy production and conversion]; Region: COG1146
699034002461	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
699034002462	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
699034002463	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034002464	Walker A/P-loop; other site
699034002465	ATP binding site [chemical binding]; other site
699034002466	Q-loop/lid; other site
699034002467	ABC transporter signature motif; other site
699034002468	Walker B; other site
699034002469	D-loop; other site
699034002470	H-loop/switch region; other site
699034002471	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
699034002472	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
699034002473	ligand binding site [chemical binding]; other site
699034002474	flexible hinge region; other site
699034002475	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cd00092
699034002476	putative switch regulator; other site
699034002477	non-specific DNA interactions [nucleotide binding]; other site
699034002478	DNA binding site [nucleotide binding]
699034002479	sequence specific DNA binding site [nucleotide binding]; other site
699034002480	putative cAMP binding site [chemical binding]; other site
699034002481	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
699034002482	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
699034002483	Predicted transcriptional regulators [Transcription]; Region: COG1695
699034002484	DNA alkylation repair enzyme [DNA replication, recombination, and repair]; Region: COG4335
699034002485	SnoaL-like domain; Region: SnoaL_2; pfam12680
699034002486	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
699034002487	Putative lysophospholipase; Region: Hydrolase_4; cl19140
699034002488	Radical SAM superfamily; Region: Radical_SAM; pfam04055
699034002489	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
699034002490	FeS/SAM binding site; other site
699034002491	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
699034002492	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
699034002493	Coenzyme A binding pocket [chemical binding]; other site
699034002494	Domain of unknown function (DUF3841); Region: DUF3841; pfam12952
699034002495	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034002496	sequence-specific DNA binding site [nucleotide binding]; other site
699034002497	salt bridge; other site
699034002498	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034002499	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034002500	active site
699034002501	phosphorylation site [posttranslational modification]
699034002502	intermolecular recognition site; other site
699034002503	dimerization interface [polypeptide binding]; other site
699034002504	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034002505	DNA binding site [nucleotide binding]
699034002506	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034002507	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034002508	dimer interface [polypeptide binding]; other site
699034002509	phosphorylation site [posttranslational modification]
699034002510	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034002511	ATP binding site [chemical binding]; other site
699034002512	Mg2+ binding site [ion binding]; other site
699034002513	G-X-G motif; other site
699034002514	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
699034002515	ATP-binding cassette domain of the bacitracin-resistance transporter; Region: ABC_BcrA_bacitracin_resist; cd03268
699034002516	Walker A/P-loop; other site
699034002517	ATP binding site [chemical binding]; other site
699034002518	Q-loop/lid; other site
699034002519	ABC transporter signature motif; other site
699034002520	Walker B; other site
699034002521	D-loop; other site
699034002522	H-loop/switch region; other site
699034002523	Fic family protein [Function unknown]; Region: COG3177
699034002524	Fic/DOC family; Region: Fic; pfam02661
699034002525	Transcriptional regulators [Transcription]; Region: FadR; COG2186
699034002526	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cl17414
699034002527	DNA-binding site [nucleotide binding]; DNA binding site
699034002528	FCD domain; Region: FCD; pfam07729
699034002529	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
699034002530	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
699034002531	Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism]; Region: DAP2; COG1506
699034002532	Prolyl oligopeptidase family; Region: Peptidase_S9; pfam00326
699034002533	Predicted transcriptional regulators [Transcription]; Region: COG1725
699034002534	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
699034002535	DNA-binding site [nucleotide binding]; DNA binding site
699034002536	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
699034002537	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
699034002538	Walker A/P-loop; other site
699034002539	ATP binding site [chemical binding]; other site
699034002540	Q-loop/lid; other site
699034002541	ABC transporter signature motif; other site
699034002542	Walker B; other site
699034002543	D-loop; other site
699034002544	H-loop/switch region; other site
699034002545	ABC-2 family transporter protein; Region: ABC2_membrane_5; pfam13346
699034002546	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
699034002547	CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This...; Region: Voltage_gated_ClC; cl02915
699034002548	Cl- selectivity filter; other site
699034002549	Cl- binding residues [ion binding]; other site
699034002550	pore gating glutamate residue; other site
699034002551	dimer interface [polypeptide binding]; other site
699034002552	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
699034002553	Penicillinase repressor; Region: Penicillinase_R; cl17580
699034002554	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
699034002555	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
699034002556	DNA binding residues [nucleotide binding]
699034002557	TcdB toxin N-terminal helical domain; Region: TcdB_N; pfam12918
699034002558	TcdA/TcdB catalytic glycosyltransferase domain; Region: TcdA_TcdB; pfam12919
699034002559	Peptidase C80 family; Region: Peptidase_C80; pfam11713
699034002560	TcdA/TcdB pore forming domain; Region: TcdA_TcdB_pore; pfam12920
699034002561	glucan-binding repeat; Region: glucan_65_rpt; TIGR04035
699034002562	FOG: Glucan-binding domain (YG repeat) [General function prediction only]; Region: COG5263
699034002563	FOG: Glucan-binding domain (YG repeat) [General function prediction only]; Region: COG5263
699034002564	Holin family; Region: Phage_holin_4; cl01989
699034002565	TcdB toxin N-terminal helical domain; Region: TcdB_N; pfam12918
699034002566	TcdA/TcdB catalytic glycosyltransferase domain; Region: TcdA_TcdB; pfam12919
699034002567	Peptidase C80 family; Region: Peptidase_C80; pfam11713
699034002568	TcdA/TcdB pore forming domain; Region: TcdA_TcdB_pore; pfam12920
699034002569	FOG: Glucan-binding domain (YG repeat) [General function prediction only]; Region: COG5263
699034002570	FOG: Glucan-binding domain (YG repeat) [General function prediction only]; Region: COG5263
699034002571	FOG: Glucan-binding domain (YG repeat) [General function prediction only]; Region: COG5263
699034002572	Pathogenicity locus; Region: Cdd1; pfam11731
699034002573	Protein of unknown function (DUF3795); Region: DUF3795; pfam12675
699034002574	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4200
699034002575	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
699034002576	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
699034002577	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034002578	Walker A/P-loop; other site
699034002579	ATP binding site [chemical binding]; other site
699034002580	Q-loop/lid; other site
699034002581	ABC transporter signature motif; other site
699034002582	Walker B; other site
699034002583	D-loop; other site
699034002584	H-loop/switch region; other site
699034002585	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034002586	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034002587	active site
699034002588	phosphorylation site [posttranslational modification]
699034002589	intermolecular recognition site; other site
699034002590	dimerization interface [polypeptide binding]; other site
699034002591	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034002592	DNA binding site [nucleotide binding]
699034002593	heavy metal sensor kinase; Region: cztS_silS_copS; TIGR01386
699034002594	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034002595	dimer interface [polypeptide binding]; other site
699034002596	phosphorylation site [posttranslational modification]
699034002597	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034002598	ATP binding site [chemical binding]; other site
699034002599	Mg2+ binding site [ion binding]; other site
699034002600	G-X-G motif; other site
699034002601	Penicillinase repressor; Region: Penicillinase_R; cl17580
699034002602	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_23; cd09011
699034002603	NIF3 (NGG1p interacting factor 3); Region: NIF3; cl15371
699034002604	Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane]; Region: Cfa; COG2230
699034002605	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
699034002606	S-adenosylmethionine binding site [chemical binding]; other site
699034002607	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
699034002608	Coenzyme A binding pocket [chemical binding]; other site
699034002609	RNA polymerase sigma-70 factor, TIGR02954 family; Region: Sig70_famx3
699034002610	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
699034002611	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
699034002612	DNA binding residues [nucleotide binding]
699034002613	N-acyl-D-aspartate/D-glutamate deacylase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3653
699034002614	D-aminoacylases (N-acyl-D-Amino acid amidohydrolases) catalyze the hydrolysis of N-acyl-D-amino acids to produce the corresponding D-amino acids, which are used as intermediates in the synthesis of pesticides, bioactive peptides, and antibiotics; Region: D-aminoacylase; cd01297
699034002615	active site
699034002616	putative substrate binding pocket [chemical binding]; other site
699034002617	SnoaL-like domain; Region: SnoaL_2; pfam12680
699034002618	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
699034002619	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
699034002620	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
699034002621	benzoate transport; Region: 2A0115; TIGR00895
699034002622	putative substrate translocation pore; other site
699034002623	potential frameshift: common BLAST hit: gi|126698261|ref|YP_001087158.1| sodium:solute symporter
699034002624	Transcriptional regulators [Transcription]; Region: PurR; COG1609
699034002625	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
699034002626	DNA binding site [nucleotide binding]
699034002627	domain linker motif; other site
699034002628	Ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors; Region: PBP1_LacI_like_2; cd06278
699034002629	putative ligand binding site [chemical binding]; other site
699034002630	putative dimerization interface [polypeptide binding]; other site
699034002631	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
699034002632	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034002633	Walker A motif; other site
699034002634	ATP binding site [chemical binding]; other site
699034002635	Walker B motif; other site
699034002636	arginine finger; other site
699034002637	Peptidase family M41; Region: Peptidase_M41; pfam01434
699034002638	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
699034002639	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
699034002640	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
699034002641	50S ribosomal protein L35; Reviewed; Region: rpmI; PRK00172
699034002642	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
699034002643	23S rRNA binding site [nucleotide binding]; other site
699034002644	L21 binding site [polypeptide binding]; other site
699034002645	L13 binding site [polypeptide binding]; other site
699034002646	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
699034002647	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
699034002648	active site
699034002649	metal binding site [ion binding]; metal-binding site
699034002650	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
699034002651	active site
699034002652	metal binding site [ion binding]; metal-binding site
699034002653	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
699034002654	active site
699034002655	metal binding site [ion binding]; metal-binding site
699034002656	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
699034002657	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
699034002658	active site
699034002659	metal binding site [ion binding]; metal-binding site
699034002660	Short-chain dehydrogenases of various substrate specificities [General function prediction only]; Region: DltE; COG0300
699034002661	classical (c) SDRs; Region: SDR_c; cd05233
699034002662	NAD(P) binding site [chemical binding]; other site
699034002663	active site
699034002664	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
699034002665	Beta-lactamase superfamily domain; Region: Lactamase_B_2; pfam12706
699034002666	Helix-Turn-Helix DNA binding domain of the BmrR transcription regulator; Region: HTH_BmrR; cd01107
699034002667	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
699034002668	DNA binding residues [nucleotide binding]
699034002669	drug binding residues [chemical binding]; other site
699034002670	dimer interface [polypeptide binding]; other site
699034002671	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
699034002672	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
699034002673	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
699034002674	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_1; cd09606
699034002675	oligoendopeptidase, M3 family; Region: M3_not_pepF; TIGR02289
699034002676	active site
699034002677	Zn binding site [ion binding]; other site
699034002678	potassium uptake protein, TrkH family; Region: 2a38; TIGR00933
699034002679	Cation transport protein; Region: TrkH; cl17365
699034002680	K+ transport systems, NAD-binding component [Inorganic ion transport and metabolism]; Region: TrkA; COG0569
699034002681	TrkA-N domain; Region: TrkA_N; pfam02254
699034002682	TrkA-C domain; Region: TrkA_C; pfam02080
699034002683	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
699034002684	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; smart00967
699034002685	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
699034002686	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
699034002687	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
699034002688	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
699034002689	dimer interface [polypeptide binding]; other site
699034002690	motif 1; other site
699034002691	active site
699034002692	motif 2; other site
699034002693	motif 3; other site
699034002694	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
699034002695	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
699034002696	putative tRNA-binding site [nucleotide binding]; other site
699034002697	B3/4 domain; Region: B3_4; pfam03483
699034002698	tRNA synthetase B5 domain; Region: B5; smart00874
699034002699	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
699034002700	dimer interface [polypeptide binding]; other site
699034002701	motif 1; other site
699034002702	motif 3; other site
699034002703	motif 2; other site
699034002704	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
699034002705	Cell division protein ZapA; Region: ZapA; pfam05164
699034002706	Protein of unknown function (DUF1275); Region: DUF1275; pfam06912
699034002707	putative protease; Provisional; Region: PRK15452
699034002708	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
699034002709	Collagenase; Region: DUF3656; pfam12392
699034002710	Peptidase family U32; Region: Peptidase_U32; pfam01136
699034002711	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
699034002712	Zn2+ binding site [ion binding]; other site
699034002713	Mg2+ binding site [ion binding]; other site
699034002714	MutT homolog-1 (MTH1) is a member of the Nudix hydrolase superfamily. MTH1, the mammalian counterpart of MutT, hydrolyzes oxidized purine nucleoside triphosphates, such as 8-oxo-dGTP and 2-hydroxy-ATP, to monophosphates, thereby preventing the...; Region: MTH1; cd03427
699034002715	putative active site [active]
699034002716	nucleotide binding site [chemical binding]; other site
699034002717	nudix motif; other site
699034002718	putative metal binding site [ion binding]; other site
699034002719	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
699034002720	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
699034002721	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
699034002722	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514
699034002723	FMN binding site [chemical binding]; other site
699034002724	dimer interface [polypeptide binding]; other site
699034002725	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
699034002726	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
699034002727	substrate binding pocket [chemical binding]; other site
699034002728	membrane-bound complex binding site; other site
699034002729	hinge residues; other site
699034002730	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
699034002731	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
699034002732	substrate binding pocket [chemical binding]; other site
699034002733	membrane-bound complex binding site; other site
699034002734	hinge residues; other site
699034002735	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
699034002736	metal binding site [ion binding]; metal-binding site
699034002737	active site
699034002738	I-site; other site
699034002739	Xaa-His dipeptidase; Region: aa-his-dipept; TIGR01893
699034002740	M20 Peptidase D has specificity for beta-alanyl-L-histidine dipeptide; Region: M20_pepD; cd03890
699034002741	metal binding site [ion binding]; metal-binding site
699034002742	dimer interface [polypeptide binding]; other site
699034002743	recombination and DNA strand exchange inhibitor protein; Reviewed; Region: PRK00409
699034002744	MutS domain III; Region: MutS_III; pfam05192
699034002745	ATP-binding cassette domain of MutS2; Region: ABC_MutS2; cd03280
699034002746	Walker A/P-loop; other site
699034002747	ATP binding site [chemical binding]; other site
699034002748	Q-loop/lid; other site
699034002749	ABC transporter signature motif; other site
699034002750	Walker B; other site
699034002751	D-loop; other site
699034002752	H-loop/switch region; other site
699034002753	Apolipophorin-III and similar insect proteins; Region: ApoLp-III_like; cl19113
699034002754	Smr domain; Region: Smr; pfam01713
699034002755	Protein of unknown function (DUF523); Region: DUF523; pfam04463
699034002756	Arginyl tRNA synthetase N terminal domain; Region: Arg_tRNA_synt_N; pfam03485
699034002757	arginyl-tRNA synthetase; Reviewed; Region: PRK12451
699034002758	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
699034002759	active site
699034002760	HIGH motif; other site
699034002761	KMSK motif region; other site
699034002762	Anticodon-binding domain of arginyl tRNA synthetases; Region: Anticodon_Ia_Arg; cd07956
699034002763	tRNA binding surface [nucleotide binding]; other site
699034002764	anticodon binding site; other site
699034002765	Fe-S oxidoreductase [Energy production and conversion]; Region: COG1032
699034002766	B12 binding domain_like associated with radical SAM domain. This domain shows similarity with B12 (adenosylcobamide) binding domains found in several enzymes, such as glutamate mutase, methionine synthase and methylmalonyl-CoA mutase, but it lacks the...; Region: radical_SAM_B12_BD; cd02068
699034002767	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
699034002768	FeS/SAM binding site; other site
699034002769	Protein of unknown function (DUF4080); Region: DUF4080; pfam13311
699034002770	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
699034002771	binding surface
699034002772	TPR motif; other site
699034002773	TPR repeat; Region: TPR_11; pfam13414
699034002774	Phosphate acetyl/butaryl transferase; Region: PTA_PTB; cl17212
699034002775	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
699034002776	ACS interaction site; other site
699034002777	CODH interaction site; other site
699034002778	metal cluster binding site [ion binding]; other site
699034002779	CO dehydrogenase maturation factor [Cell division and chromosome partitioning]; Region: CooC; COG3640
699034002780	The accessory protein CooC, which contains a nucleotide-binding domain (P-loop) near the N-terminus, participates in the maturation of the nickel center of carbon monoxide dehydrogenase (CODH). CODH from Rhodospirillum rubrum catalyzes the reversible...; Region: CooC; cd02034
699034002781	Nucleoside/nucleotide kinase (NK) is a protein superfamily consisting of multiple families of enzymes that share structural similarity and are functionally related to the catalysis of the reversible phosphate group transfer from nucleoside triphosphates...; Region: NK; cl17190
699034002782	P-loop; other site
699034002783	formate--tetrahydrofolate ligase; Provisional; Region: PRK13505
699034002784	Formyltetrahydrofolate synthetase (FTHFS) catalyzes the ATP-dependent activation of formate ion via its addition to the N10 position of tetrahydrofolate. FTHFS is a highly expressed key enzyme in both the Wood-Ljungdahl pathway of autotrophic CO2...; Region: FTHFS; cd00477
699034002785	Potassium binding sites [ion binding]; other site
699034002786	Cesium cation binding sites [ion binding]; other site
699034002787	Formiminotransferase-cyclodeaminase; Region: FTCD_C; pfam04961
699034002788	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14190
699034002789	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
699034002790	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
699034002791	homodimer interface [polypeptide binding]; other site
699034002792	NADP binding site [chemical binding]; other site
699034002793	substrate binding site [chemical binding]; other site
699034002794	Methylene-tetrahydrofolate reductase C terminal; Region: MTHFR_C; pfam12225
699034002795	Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase...; Region: MTHFR; cd00537
699034002796	FAD binding site [chemical binding]; other site
699034002797	dihydrolipoamide dehydrogenase; Region: lipoamide_DH; TIGR01350
699034002798	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
699034002799	Pyridine nucleotide-disulphide oxidoreductase, dimerization domain; Region: Pyr_redox_dim; pfam02852
699034002800	The accessory protein CooC, which contains a nucleotide-binding domain (P-loop) near the N-terminus, participates in the maturation of the nickel center of carbon monoxide dehydrogenase (CODH). CODH from Rhodospirillum rubrum catalyzes the reversible...; Region: CooC; cd02034
699034002801	CO dehydrogenase maturation factor [Cell division and chromosome partitioning]; Region: CooC; COG3640
699034002802	P-loop; other site
699034002803	acetyl-CoA decarbonylase/synthase complex subunit delta; Provisional; Region: PRK04452
699034002804	acetyl-CoA decarbonylase/synthase complex subunit gamma; Provisional; Region: PRK04165
699034002805	Putative Fe-S cluster; Region: FeS; pfam04060
699034002806	Pterin binding enzymes. This family includes dihydropteroate synthase (DHPS) and cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  DHPS, a...; Region: Pterin_binding; cl00219
699034002807	Pterin binding enzymes. This family includes dihydropteroate synthase (DHPS) and cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  DHPS, a...; Region: Pterin_binding; cl00219
699034002808	Methionine synthase I, cobalamin-binding domain [Amino acid transport and metabolism]; Region: MetH; COG1410
699034002809	substrate binding pocket [chemical binding]; other site
699034002810	dimer interface [polypeptide binding]; other site
699034002811	inhibitor binding site; inhibition site
699034002812	bifunctional acetyl-CoA decarbonylase/synthase complex subunit alpha/beta; Reviewed; Region: PRK09529
699034002813	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
699034002814	ACS interaction site; other site
699034002815	CODH interaction site; other site
699034002816	metal cluster binding site [ion binding]; other site
699034002817	CO dehydrogenase/acetyl-CoA synthase complex beta subunit; Region: CdhC; pfam03598
699034002818	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
699034002819	lipoyl attachment site [posttranslational modification]; other site
699034002820	Uncharacterized metal-binding protein [General function prediction only]; Region: COG3894
699034002821	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
699034002822	catalytic loop [active]
699034002823	iron binding site [ion binding]; other site
699034002824	Domain of unknown function (DUF4445); Region: DUF4445; pfam14574
699034002825	Uncharacterized homolog of biotin synthetase [Function unknown]; Region: COG1856
699034002826	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl18962
699034002827	Biotin and Thiamin Synthesis associated domain; Region: BATS; cl06149
699034002828	Biotin synthase-related enzyme [General function prediction only]; Region: COG2516
699034002829	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
699034002830	FeS/SAM binding site; other site
699034002831	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
699034002832	Predicted RNA-binding protein; Region: RNA_bind_2; pfam10133
699034002833	Domain of unknown function (DUF3842); Region: DUF3842; pfam12953
699034002834	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase of Hisj like; Region: PHP_HisPPase_Hisj_like; cd12110
699034002835	histidinol phosphate phosphatase, HisJ family; Region: hisJ_fam; TIGR01856
699034002836	active site
699034002837	dimer interface [polypeptide binding]; other site
699034002838	Domain of unknown function (DUF4300); Region: DUF4300; pfam14133
699034002839	Domains similar to the Pancreatic-derived factor; Region: PANDER_like; cl19122
699034002840	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
699034002841	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
699034002842	catalytic residue [active]
699034002843	glycerol kinase; Provisional; Region: glpK; PRK00047
699034002844	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
699034002845	N- and C-terminal domain interface [polypeptide binding]; other site
699034002846	active site
699034002847	MgATP binding site [chemical binding]; other site
699034002848	catalytic site [active]
699034002849	metal binding site [ion binding]; metal-binding site
699034002850	glycerol binding site [chemical binding]; other site
699034002851	homotetramer interface [polypeptide binding]; other site
699034002852	homodimer interface [polypeptide binding]; other site
699034002853	FBP binding site [chemical binding]; other site
699034002854	protein IIAGlc interface [polypeptide binding]; other site
699034002855	Ethanolamine utilisation protein, EutH; Region: EutH; pfam04346
699034002856	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
699034002857	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
699034002858	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
699034002859	Flagellar motor component [Cell motility and secretion]; Region: MotA; COG1291
699034002860	Flagellar motor protein [Cell motility and secretion]; Region: MotB; COG1360
699034002861	Membrane MotB of proton-channel complex MotA/MotB; Region: MotB_plug; pfam13677
699034002862	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
699034002863	ligand binding site [chemical binding]; other site
699034002864	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
699034002865	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
699034002866	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
699034002867	metal binding site [ion binding]; metal-binding site
699034002868	active site
699034002869	I-site; other site
699034002870	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
699034002871	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
699034002872	Part of AAA domain; Region: AAA_19; pfam13245
699034002873	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538
699034002874	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
699034002875	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
699034002876	substrate binding pocket [chemical binding]; other site
699034002877	membrane-bound complex binding site; other site
699034002878	hinge residues; other site
699034002879	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
699034002880	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034002881	dimer interface [polypeptide binding]; other site
699034002882	conserved gate region; other site
699034002883	putative PBP binding loops; other site
699034002884	ABC-ATPase subunit interface; other site
699034002885	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
699034002886	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
699034002887	Walker A/P-loop; other site
699034002888	ATP binding site [chemical binding]; other site
699034002889	Q-loop/lid; other site
699034002890	ABC transporter signature motif; other site
699034002891	Walker B; other site
699034002892	D-loop; other site
699034002893	H-loop/switch region; other site
699034002894	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
699034002895	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
699034002896	catalytic residue [active]
699034002897	thiamine biosynthesis protein ThiI; Provisional; Region: PRK01565
699034002898	THUMP domain of thiamine biosynthesis protein ThiI; Region: THUMP_ThiI; cd11716
699034002899	ThiI is required for thiazole synthesis in the thiamine biosynthesis pathway. It belongs to the Adenosine Nucleotide Hydrolysis suoerfamily and predicted to bind to Adenosine nucleotide; Region: ThiI; cd01712
699034002900	Ligand Binding Site [chemical binding]; other site
699034002901	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
699034002902	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
699034002903	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514
699034002904	FMN binding site [chemical binding]; other site
699034002905	dimer interface [polypeptide binding]; other site
699034002906	PAS fold; Region: PAS_3; pfam08447
699034002907	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
699034002908	metal binding site [ion binding]; metal-binding site
699034002909	active site
699034002910	I-site; other site
699034002911	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
699034002912	pyruvate formate lyase-activating enzyme 1; Provisional; Region: pflA; PRK11145
699034002913	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
699034002914	FeS/SAM binding site; other site
699034002915	formate acetyltransferase 1; Region: pyr_form_ly_1; TIGR01255
699034002916	Pyruvate formate lyase 1; Region: PFL1; cd01678
699034002917	coenzyme A binding site [chemical binding]; other site
699034002918	active site
699034002919	catalytic residues [active]
699034002920	glycine loop; other site
699034002921	K+-dependent Na+/Ca+ exchanger related-protein; Region: TIGR00367
699034002922	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
699034002923	Sodium/calcium exchanger protein; Region: Na_Ca_ex; pfam01699
699034002924	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
699034002925	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
699034002926	ATP binding site [chemical binding]; other site
699034002927	Mg++ binding site [ion binding]; other site
699034002928	motif III; other site
699034002929	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
699034002930	nucleotide binding region [chemical binding]; other site
699034002931	ATP-binding site [chemical binding]; other site
699034002932	RNA recognition motif in the DbpA subfamily of prokaryotic DEAD-box rRNA helicases; Region: RRM_DbpA; cd12252
699034002933	RNA binding site [nucleotide binding]; other site
699034002934	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
699034002935	Mga helix-turn-helix domain; Region: Mga; pfam05043
699034002936	PRD domain; Region: PRD; pfam00874
699034002937	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
699034002938	active site
699034002939	P-loop; other site
699034002940	phosphorylation site [posttranslational modification]
699034002941	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; Region: PTS_EIIA_2; pfam00359
699034002942	active site
699034002943	phosphorylation site [posttranslational modification]
699034002944	Glucitol operon activator protein (GutM); Region: GutM; pfam06923
699034002945	PTS system enzyme II sorbitol-specific factor; Region: EII-GUT; pfam03608
699034002946	Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Region: SrlE; COG3732
699034002947	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
699034002948	Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Region: SrlE; COG3732
699034002949	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
699034002950	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
699034002951	PTS system glucitol/sorbitol-specific IIA component; Region: PTSIIA_gutA; pfam03829
699034002952	sorbitol-6-phosphate dehydrogenase; Provisional; Region: PRK12384
699034002953	Sorbitol 6-phosphate dehydrogenase (SDH), classical (c) SDRs; Region: SDH_SDR_c_like; cd05322
699034002954	putative NAD(P) binding site [chemical binding]; other site
699034002955	active site
699034002956	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
699034002957	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
699034002958	Probable transposase; Region: OrfB_IS605; pfam01385
699034002959	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
699034002960	The MopB_3 CD includes a group of related uncharacterized bacterial and archaeal molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. These members...; Region: MopB_3; cd02766
699034002961	putative [4Fe-4S] binding site [ion binding]; other site
699034002962	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
699034002963	putative molybdopterin cofactor binding site [chemical binding]; other site
699034002964	Molybdopterin-Binding, C-terminal (MopB_CT) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum-...; Region: MopB_CT; cd02775
699034002965	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
699034002966	anti sigma factor interaction site; other site
699034002967	regulatory phosphorylation site [posttranslational modification]; other site
699034002968	Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; Region: RsbW; COG2172
699034002969	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034002970	ATP binding site [chemical binding]; other site
699034002971	Mg2+ binding site [ion binding]; other site
699034002972	G-X-G motif; other site
699034002973	sporulation sigma factor SigF; Validated; Region: PRK05572
699034002974	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
699034002975	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
699034002976	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
699034002977	DNA binding residues [nucleotide binding]
699034002978	SpoVA protein; Region: SpoVA; cl04298
699034002979	stage V sporulation protein AD; Validated; Region: PRK08304
699034002980	stage V sporulation protein AD; Region: spore_V_AD; TIGR02845
699034002981	SpoVA protein; Region: SpoVA; pfam03862
699034002982	Transcriptional regulators [Transcription]; Region: PurR; COG1609
699034002983	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
699034002984	DNA binding site [nucleotide binding]
699034002985	domain linker motif; other site
699034002986	Ligand binding domain of the LacI tanscriptional regulator family belonging to the type I periplasmic-binding fold protein superfamily; Region: PBP1_LacI_sugar_binding_like; cd06267
699034002987	ligand binding site [chemical binding]; other site
699034002988	dimerization interface [polypeptide binding]; other site
699034002989	Protein of unknown function (DUF3100); Region: DUF3100; pfam11299
699034002990	M20 Peptidase Aminoacylase 1-like protein 2-like, amidohydrolase subfamily; Region: M20_ACY1L2_like; cd05672
699034002991	amidohydrolase; Region: amidohydrolases; TIGR01891
699034002992	metal binding site [ion binding]; metal-binding site
699034002993	Protein of unknown function (DUF1177); Region: DUF1177; pfam06675
699034002994	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
699034002995	active site
699034002996	catalytic motif [active]
699034002997	Zn binding site [ion binding]; other site
699034002998	Transglycosylase; Region: Transgly; pfam00912
699034002999	penicillin-binding protein, 1A family; Region: PBP_1a_fam; TIGR02074
699034003000	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
699034003001	Sporulation protein YunB (Spo_YunB); Region: Spore_YunB; cl09783
699034003002	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
699034003003	SpoIVB peptidase S55; Region: Peptidase_S55; pfam05580
699034003004	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
699034003005	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
699034003006	active site
699034003007	metal binding site [ion binding]; metal-binding site
699034003008	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
699034003009	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
699034003010	ABC transporter; Region: ABC_tran_2; pfam12848
699034003011	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
699034003012	Cysteine-rich small domain; Region: zf-like; pfam04071
699034003013	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
699034003014	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
699034003015	HflX GTPase family; Region: HflX; cd01878
699034003016	G1 box; other site
699034003017	GTP/Mg2+ binding site [chemical binding]; other site
699034003018	Switch I region; other site
699034003019	G2 box; other site
699034003020	G3 box; other site
699034003021	Switch II region; other site
699034003022	G4 box; other site
699034003023	G5 box; other site
699034003024	HEAT repeats; Region: HEAT_2; pfam13646
699034003025	Diadenosine hexaphosphate (Ap6A) hydrolase is a member of the Nudix hydrolase superfamily. Ap6A hydrolase specifically hydrolyzes diadenosine polyphosphates, but not ATP or diadenosine triphosphate, and it generates ATP as the product. Ap6A, the most...; Region: Ap6A_hydrolase; cd03673
699034003026	active site
699034003027	Ap6A binding site [chemical binding]; other site
699034003028	nudix motif; other site
699034003029	metal binding site [ion binding]; metal-binding site
699034003030	Uncharacterized conserved protein [Function unknown]; Region: COG1739
699034003031	Uncharacterized protein family UPF0029; Region: UPF0029; pfam01205
699034003032	Domain of unknown function (DUF1949); Region: DUF1949; pfam09186
699034003033	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
699034003034	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
699034003035	NAD+ synthase is a homodimer, which catalyzes the final step in de novo nicotinamide adenine dinucleotide (NAD+) biosynthesis, an amide transfer from either ammonia or glutamine to nicotinic acid adenine dinucleotide (NaAD). The conversion of NaAD to NAD...; Region: NAD_synthase; cd00553
699034003036	homodimer interface [polypeptide binding]; other site
699034003037	NAD binding pocket [chemical binding]; other site
699034003038	ATP binding pocket [chemical binding]; other site
699034003039	Mg binding site [ion binding]; other site
699034003040	active-site loop [active]
699034003041	hypothetical protein; Validated; Region: PRK00110
699034003042	Transcriptional regulators [Transcription]; Region: PurR; COG1609
699034003043	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
699034003044	DNA binding site [nucleotide binding]
699034003045	Ligand-binding domain of DNA transcription repressor for the hexuronate utilization operon from Bacillus species and its close homologs from other bacteria, all of which are a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_hexuronate_repressor_like; cd06272
699034003046	putative dimerization interface [polypeptide binding]; other site
699034003047	putative ligand binding site [chemical binding]; other site
699034003048	3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain; Region: DRE_TIM_HMGL; cd07938
699034003049	active site
699034003050	catalytic residues [active]
699034003051	metal binding site [ion binding]; metal-binding site
699034003052	Dicarboxylate carrier protein MatC N-terminus; Region: MatC_N; pfam07158
699034003053	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
699034003054	transmembrane helices; other site
699034003055	Citrate transporter; Region: CitMHS; pfam03600
699034003056	Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804
699034003057	3-hydroxybutyryl-CoA dehydratase; Validated; Region: PRK05809
699034003058	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
699034003059	substrate binding site [chemical binding]; other site
699034003060	oxyanion hole (OAH) forming residues; other site
699034003061	trimer interface [polypeptide binding]; other site
699034003062	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
699034003063	fructuronate transporter; Provisional; Region: PRK10034; cl15264
699034003064	Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion]; Region: CaiB; COG1804
699034003065	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
699034003066	Acyl-CoA dehydrogenase; Region: ACAD; cl09933
699034003067	active site
699034003068	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
699034003069	Ligand binding site [chemical binding]; other site
699034003070	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
699034003071	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
699034003072	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
699034003073	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
699034003074	PAS domain; Region: PAS_9; pfam13426
699034003075	putative active site [active]
699034003076	phage shock protein operon transcriptional activator; Provisional; Region: pspF; PRK11608
699034003077	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034003078	Walker A motif; other site
699034003079	ATP binding site [chemical binding]; other site
699034003080	Walker B motif; other site
699034003081	arginine finger; other site
699034003082	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
699034003083	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034003084	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034003085	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034003086	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034003087	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034003088	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034003089	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
699034003090	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
699034003091	metal binding site [ion binding]; metal-binding site
699034003092	active site
699034003093	I-site; other site
699034003094	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
699034003095	Usp: Universal stress protein family. The universal stress protein Usp is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. Usp enhances the rate of cell survival during prolonged exposure to...; Region: USP_Like; cd00293
699034003096	Ligand Binding Site [chemical binding]; other site
699034003097	PTS system, Lactose/Cellobiose specific IIB subunit; Region: PTS_IIB; pfam02302
699034003098	Transcriptional regulators [Transcription]; Region: FadR; COG2186
699034003099	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
699034003100	DNA-binding site [nucleotide binding]; DNA binding site
699034003101	FCD domain; Region: FCD; pfam07729
699034003102	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
699034003103	Major Facilitator Superfamily; Region: MFS_1; pfam07690
699034003104	putative substrate translocation pore; other site
699034003105	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
699034003106	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
699034003107	active site turn [active]
699034003108	phosphorylation site [posttranslational modification]
699034003109	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
699034003110	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
699034003111	HPr interaction site; other site
699034003112	glycerol kinase (GK) interaction site [polypeptide binding]; other site
699034003113	active site
699034003114	phosphorylation site [posttranslational modification]
699034003115	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
699034003116	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; pfam00232
699034003117	transcriptional antiterminator BglG; Provisional; Region: PRK09772
699034003118	CAT RNA binding domain; Region: CAT_RBD; smart01061
699034003119	PRD domain; Region: PRD; pfam00874
699034003120	PRD domain; Region: PRD; pfam00874
699034003121	proteobacterial dedicated sortase system response regulator; Region: marine_sort_RR; TIGR03787
699034003122	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034003123	active site
699034003124	phosphorylation site [posttranslational modification]
699034003125	intermolecular recognition site; other site
699034003126	dimerization interface [polypeptide binding]; other site
699034003127	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034003128	DNA binding site [nucleotide binding]
699034003129	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034003130	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034003131	dimer interface [polypeptide binding]; other site
699034003132	phosphorylation site [posttranslational modification]
699034003133	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034003134	ATP binding site [chemical binding]; other site
699034003135	Mg2+ binding site [ion binding]; other site
699034003136	G-X-G motif; other site
699034003137	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
699034003138	ATP-binding cassette domain of the bacitracin-resistance transporter; Region: ABC_BcrA_bacitracin_resist; cd03268
699034003139	Walker A/P-loop; other site
699034003140	ATP binding site [chemical binding]; other site
699034003141	Q-loop/lid; other site
699034003142	ABC transporter signature motif; other site
699034003143	Walker B; other site
699034003144	D-loop; other site
699034003145	H-loop/switch region; other site
699034003146	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
699034003147	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
699034003148	Rubrerythrin [Energy production and conversion]; Region: COG1592
699034003149	Rubrerythrin, ferritin-like diiron-binding domain; Region: Rubrerythrin; cd01041
699034003150	binuclear metal center [ion binding]; other site
699034003151	Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and...; Region: rubredoxin_SM; cd00729
699034003152	iron binding site [ion binding]; other site
699034003153	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
699034003154	metal binding site 2 [ion binding]; metal-binding site
699034003155	putative DNA binding helix; other site
699034003156	metal binding site 1 [ion binding]; metal-binding site
699034003157	dimer interface [polypeptide binding]; other site
699034003158	structural Zn2+ binding site [ion binding]; other site
699034003159	Desulforedoxin (DSRD) domain; a small non-heme iron domain present in the desulforedoxin (rubredoxin oxidoreductase) and desulfoferrodoxin proteins of some archeael and bacterial methanogens and sulfate/sulfur reducers. Desulforedoxin is a small; Region: DSRD; cl00018
699034003160	non-heme iron binding site [ion binding]; other site
699034003161	Desulfoferrodoxin [Energy production and conversion]; Region: COG2033
699034003162	dimer interface [polypeptide binding]; other site
699034003163	Desulfoferrodoxin; Region: Desulfoferrodox; pfam01880
699034003164	non-heme iron binding site [ion binding]; other site
699034003165	Rubredoxin [Energy production and conversion]; Region: COG1773
699034003166	Rubredoxin; nonheme iron binding domains containing a [Fe(SCys)4] center. Rubredoxins are small nonheme iron proteins. The iron atom is coordinated by four cysteine residues (Fe(S-Cys)4), but iron can also be replaced by cobalt, nickel or zinc. They are...; Region: rubredoxin; cd00730
699034003167	iron binding site [ion binding]; other site
699034003168	Glutamate synthase (GltS) FMN-binding domain.  GltS is a complex iron-sulfur flavoprotein that catalyzes the reductive synthesis of L-glutamate from 2-oxoglutarate and L-glutamine via intramolecular channelling of ammonia, a reaction in the plant, yeast...; Region: GltS_FMN; cd02808
699034003169	Conserved region in glutamate synthase; Region: Glu_synthase; pfam01645
699034003170	active site
699034003171	FMN binding site [chemical binding]; other site
699034003172	substrate binding site [chemical binding]; other site
699034003173	3Fe-4S cluster binding site [ion binding]; other site
699034003174	Metal-dependent hydrolases of the beta-lactamase superfamily II [General function prediction only]; Region: COG1237
699034003175	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
699034003176	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
699034003177	DEAD-like helicases superfamily; Region: DEXDc; smart00487
699034003178	ATP binding site [chemical binding]; other site
699034003179	Mg++ binding site [ion binding]; other site
699034003180	motif III; other site
699034003181	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
699034003182	nucleotide binding region [chemical binding]; other site
699034003183	ATP-binding site [chemical binding]; other site
699034003184	trans-homoaconitate synthase; Reviewed; Region: aksA; PRK11858
699034003185	Streptomyces rubellomurinus FrbC and related proteins, catalytic TIM barrel domain; Region: DRE_TIM_NifV; cd07939
699034003186	active site
699034003187	catalytic residues [active]
699034003188	metal binding site [ion binding]; metal-binding site
699034003189	aconitate hydratase; Validated; Region: PRK07229
699034003190	Aconitase catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle; Region: AcnA_Bact; cd01585
699034003191	substrate binding site [chemical binding]; other site
699034003192	ligand binding site [chemical binding]; other site
699034003193	Aconitase swivel domain. Aconitase (aconitate hydratase) catalyzes the reversible isomerization of citrate and isocitrate as part of the TCA cycle. This is the aconitase swivel domain, which undergoes swivelling conformational change in the enzyme...; Region: Aconitase_swivel; cl00215
699034003194	substrate binding site [chemical binding]; other site
699034003195	Isocitrate/isopropylmalate dehydrogenase [Amino acid transport and metabolism]; Region: LeuB; COG0473
699034003196	Transcriptional regulators [Transcription]; Region: MarR; COG1846
699034003197	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
699034003198	dimerization interface [polypeptide binding]; other site
699034003199	putative Zn2+ binding site [ion binding]; other site
699034003200	putative DNA binding site [nucleotide binding]; other site
699034003201	Acetyltransferase (GNAT) domain; Region: Acetyltransf_8; pfam13523
699034003202	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
699034003203	Coenzyme A binding pocket [chemical binding]; other site
699034003204	NAD(P)H:flavin oxidoreductase-like family 2.  A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes; Region: NADPH_oxidoreductase_2; cd02151
699034003205	putative FMN binding site [chemical binding]; other site
699034003206	Trp repressor protein; Region: Trp_repressor; cl17266
699034003207	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cl17402
699034003208	DNA binding site [nucleotide binding]
699034003209	CAAX protease self-immunity; Region: Abi; pfam02517
699034003210	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
699034003211	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
699034003212	5-aminoimidazole-4-carboxamide ribonucleotide transformylase; Provisional; Region: PRK07106
699034003213	AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) [Nucleotide transport and metabolism]; Region: PurH; COG0138
699034003214	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cl00120
699034003215	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
699034003216	Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate...; Region: Glycosyltransferase_GTB_type; cl10013
699034003217	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034003218	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034003219	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034003220	GIY-YIG domain of LuxR and ArsR family transcriptional regulators, and uncharacterized hypothetical proteins found in bacteria; Region: GIY-YIG_LuxR_like; cd10451
699034003221	GIY-YIG motif/motif A; other site
699034003222	Bacteriophage Lambda NinG protein; Region: NinG; pfam05766
699034003223	M20 Peptidase Aminoacylase 1-like protein 2 aminobenzoyl-glutamate utilization protein B subfamily; Region: M20_Acy1L2_AbgB; cd05673
699034003224	amidohydrolase; Region: amidohydrolases; TIGR01891
699034003225	putative metal binding site [ion binding]; other site
699034003226	NifU-like domain; Region: NifU; cl00484
699034003227	TIGR03987 family protein; Region: TIGR03987
699034003228	Transcriptional regulators [Transcription]; Region: MarR; COG1846
699034003229	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
699034003230	putative DNA binding site [nucleotide binding]; other site
699034003231	putative Zn2+ binding site [ion binding]; other site
699034003232	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
699034003233	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034003234	dimer interface [polypeptide binding]; other site
699034003235	conserved gate region; other site
699034003236	putative PBP binding loops; other site
699034003237	ABC-ATPase subunit interface; other site
699034003238	nickel ABC transporter, permease subunit NikC; Region: nickel_nikC; TIGR02790
699034003239	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034003240	dimer interface [polypeptide binding]; other site
699034003241	conserved gate region; other site
699034003242	putative PBP binding loops; other site
699034003243	ABC-ATPase subunit interface; other site
699034003244	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
699034003245	The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like_19; cd08518
699034003246	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
699034003247	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
699034003248	Walker A/P-loop; other site
699034003249	ATP binding site [chemical binding]; other site
699034003250	Q-loop/lid; other site
699034003251	ABC transporter signature motif; other site
699034003252	Walker B; other site
699034003253	D-loop; other site
699034003254	H-loop/switch region; other site
699034003255	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
699034003256	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
699034003257	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
699034003258	Walker A/P-loop; other site
699034003259	ATP binding site [chemical binding]; other site
699034003260	Q-loop/lid; other site
699034003261	ABC transporter signature motif; other site
699034003262	Walker B; other site
699034003263	D-loop; other site
699034003264	H-loop/switch region; other site
699034003265	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
699034003266	'potential frameshift: common BLAST hit: gi|260686156|ref|YP_003217289.1| sigma-54 factor, interaction domain-containing'
699034003267	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
699034003268	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
699034003269	active site
699034003270	P-loop; other site
699034003271	phosphorylation site [posttranslational modification]
699034003272	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
699034003273	methionine cluster; other site
699034003274	PTS system, Lactose/Cellobiose specific IIA subunit; Region: PTS_IIA; pfam02255
699034003275	active site
699034003276	phosphorylation site [posttranslational modification]
699034003277	metal binding site [ion binding]; metal-binding site
699034003278	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
699034003279	Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases; Region: GH4_GlvA_pagL_like; cd05298
699034003280	NAD binding site [chemical binding]; other site
699034003281	sugar binding site [chemical binding]; other site
699034003282	divalent metal binding site [ion binding]; other site
699034003283	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
699034003284	dimer interface [polypeptide binding]; other site
699034003285	hypothetical protein; Provisional; Region: PRK04143
699034003286	ADP-ribose binding site [chemical binding]; other site
699034003287	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
699034003288	Prolyl oligopeptidase family; Region: Peptidase_S9; cl19144
699034003289	Helix-turn-helix domain; Region: HTH_17; pfam12728
699034003290	PBP superfamily domain; Region: PBP_like; pfam12727
699034003291	ABC-type molybdate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: ModA; COG0725
699034003292	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
699034003293	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034003294	dimer interface [polypeptide binding]; other site
699034003295	conserved gate region; other site
699034003296	putative PBP binding loops; other site
699034003297	ABC-ATPase subunit interface; other site
699034003298	ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: CysA; COG1118
699034003299	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034003300	Walker A/P-loop; other site
699034003301	ATP binding site [chemical binding]; other site
699034003302	Q-loop/lid; other site
699034003303	ABC transporter signature motif; other site
699034003304	Walker B; other site
699034003305	D-loop; other site
699034003306	H-loop/switch region; other site
699034003307	maltose O-acetyltransferase; Provisional; Region: PRK10092
699034003308	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
699034003309	active site
699034003310	substrate binding site [chemical binding]; other site
699034003311	trimer interface [polypeptide binding]; other site
699034003312	CoA binding site [chemical binding]; other site
699034003313	Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325
699034003314	zinc binding site [ion binding]; other site
699034003315	putative ligand binding site [chemical binding]; other site
699034003316	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: PhnK; COG1101
699034003317	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034003318	Walker A/P-loop; other site
699034003319	ATP binding site [chemical binding]; other site
699034003320	Q-loop/lid; other site
699034003321	ABC transporter signature motif; other site
699034003322	Walker B; other site
699034003323	D-loop; other site
699034003324	H-loop/switch region; other site
699034003325	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cd06574
699034003326	TM-ABC transporter signature motif; other site
699034003327	Type I periplasmic ligand-binding domain of uncharacterized ABC-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions; Region: PBP1_ABC_uncharacterized_transporter; cd06325
699034003328	Periplasmic binding protein domain; Region: Peripla_BP_4; pfam13407
699034003329	zinc binding site [ion binding]; other site
699034003330	putative ligand binding site [chemical binding]; other site
699034003331	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: PhnK; COG1101
699034003332	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034003333	Walker A/P-loop; other site
699034003334	ATP binding site [chemical binding]; other site
699034003335	Q-loop/lid; other site
699034003336	ABC transporter signature motif; other site
699034003337	Walker B; other site
699034003338	D-loop; other site
699034003339	H-loop/switch region; other site
699034003340	Branched-chain amino acid transport system / permease component; Region: BPD_transp_2; pfam02653
699034003341	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cd06574
699034003342	TM-ABC transporter signature motif; other site
699034003343	YjeF-related protein N-terminus; Region: YjeF_N; pfam03853
699034003344	B.subtilis YXKO protein of unknown function and related proteins. Based on the conservation of the ATP binding site, the substrate binding site and the Mg2+binding site and structural homology this group is a member of the ribokinase-like superfamily; Region: YXKO-related; cd01171
699034003345	putative substrate binding site [chemical binding]; other site
699034003346	putative ATP binding site [chemical binding]; other site
699034003347	Transposase IS200 like; Region: Y1_Tnp; cl00848
699034003348	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
699034003349	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
699034003350	Probable transposase; Region: OrfB_IS605; pfam01385
699034003351	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
699034003352	Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: COG1585
699034003353	Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones]; Region: HflC; COG0330
699034003354	Band_7_stomatin_like: A subgroup of the band 7 domain of flotillin (reggie) like proteins similar to stomatin and podicin (two lipid raft-associated integral membrane proteins). Individual proteins of this band 7 domain family may cluster to form...; Region: Band_7_stomatin_like; cd03403
699034003355	glucose-1-phosphate adenylyltransferase; Provisional; Region: glgC; PRK05293
699034003356	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
699034003357	ligand binding site; other site
699034003358	oligomer interface; other site
699034003359	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
699034003360	dimer interface [polypeptide binding]; other site
699034003361	N-terminal domain interface [polypeptide binding]; other site
699034003362	sulfate 1 binding site; other site
699034003363	glucose-1-phosphate adenylyltransferase, GlgD subunit; Region: glgD; TIGR02092
699034003364	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
699034003365	ligand binding site; other site
699034003366	oligomer interface; other site
699034003367	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
699034003368	dimer interface [polypeptide binding]; other site
699034003369	N-terminal domain interface [polypeptide binding]; other site
699034003370	sulfate 1 binding site; other site
699034003371	glycogen synthase; Provisional; Region: glgA; PRK00654
699034003372	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
699034003373	ADP-binding pocket [chemical binding]; other site
699034003374	homodimer interface [polypeptide binding]; other site
699034003375	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
699034003376	homodimer interface [polypeptide binding]; other site
699034003377	glycogen/starch/alpha-glucan phosphorylases; Region: P_ylase; TIGR02093
699034003378	active site pocket [active]
699034003379	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
699034003380	Alpha amylase, catalytic domain; Region: Alpha-amylase; pfam00128
699034003381	active site
699034003382	homodimer interface [polypeptide binding]; other site
699034003383	catalytic site [active]
699034003384	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
699034003385	DNA-binding site [nucleotide binding]; DNA binding site
699034003386	phosphonate utilization associated transcriptional regulator; Region: phnR_burk; TIGR03338
699034003387	FCD domain; Region: FCD; pfam07729
699034003388	Arginine/lysine/ornithine decarboxylases [Amino acid transport and metabolism]; Region: LdcC; COG1982
699034003389	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl18945
699034003390	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
699034003391	catalytic residue [active]
699034003392	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
699034003393	S-adenosylmethionine decarboxylase proenzyme, Bacillus form; Region: SAM_DCase_Bsu; TIGR03330
699034003394	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
699034003395	S-adenosylmethionine binding site [chemical binding]; other site
699034003396	Agmatinase and related proteins; Region: Agmatinase-like_2; cd11593
699034003397	putative active site [active]
699034003398	Mn binding site [ion binding]; other site
699034003399	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
699034003400	DNA-binding site [nucleotide binding]; DNA binding site
699034003401	RNA-binding motif; other site
699034003402	[FeFe] hydrogenase, group B1/B3; Region: FeFe_hydrog_B1; TIGR04105
699034003403	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
699034003404	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
699034003405	Iron only hydrogenase large subunit, C-terminal domain; Region: Fe_hyd_lg_C; pfam02906
699034003406	[FeFe] hydrogenase, group B1/B3; Region: FeFe_hydrog_B1; TIGR04105
699034003407	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
699034003408	Iron only hydrogenase large subunit, C-terminal domain; Region: Fe_hyd_lg_C; pfam02906
699034003409	Metallo-beta-lactamase superfamily; Region: Lactamase_B; cl00446
699034003410	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
699034003411	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
699034003412	Probable transposase; Region: OrfB_IS605; pfam01385
699034003413	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
699034003414	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
699034003415	isoleucine-tRNA ligase, putative; Provisional; Region: PTZ00427
699034003416	Domain of unknown function (DUF1846); Region: DUF1846; pfam08903
699034003417	DNA Polymerase IV/Kappa; Region: PolY_Pol_IV_kappa; cd03586
699034003418	active site
699034003419	DNA polymerase IV; Validated; Region: PRK02406
699034003420	DNA binding site [nucleotide binding]
699034003421	ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism]; Region: OpuBA; COG1125
699034003422	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034003423	Walker A/P-loop; other site
699034003424	ATP binding site [chemical binding]; other site
699034003425	Q-loop/lid; other site
699034003426	ABC transporter signature motif; other site
699034003427	Walker B; other site
699034003428	D-loop; other site
699034003429	H-loop/switch region; other site
699034003430	FOG: CBS domain [General function prediction only]; Region: COG0517
699034003431	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in association with the ABC transporter OpuCA. OpuCA is the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing...; Region: CBS_pair_ABC_OpuCA_assoc2; cd04583
699034003432	ABC-type arginine/histidine transport system, permease component [Amino acid transport and metabolism]; Region: ArtM; COG4160
699034003433	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034003434	dimer interface [polypeptide binding]; other site
699034003435	conserved gate region; other site
699034003436	putative PBP binding loops; other site
699034003437	ABC-ATPase subunit interface; other site
699034003438	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
699034003439	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
699034003440	Predicted oxidoreductases of the aldo/keto reductase family [General function prediction only]; Region: COG1453
699034003441	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
699034003442	active site
699034003443	catalytic tetrad [active]
699034003444	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
699034003445	Vault protein inter-alpha-trypsin domain; Region: VIT; cl02699
699034003446	UbiA family of prenyltransferases (PTases), Unknown subgroup; Region: PT_UbiA_2; cd13963
699034003447	putative active site [active]
699034003448	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
699034003449	Putative small multi-drug export protein; Region: Sm_multidrug_ex; pfam06695
699034003450	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
699034003451	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
699034003452	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06676
699034003453	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
699034003454	RNA binding site [nucleotide binding]; other site
699034003455	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
699034003456	RNA binding site [nucleotide binding]; other site
699034003457	core domain of the SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily; Region: SPFH_like; cl19107
699034003458	S1_RPS1_repeat_ec3: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec3; cd05688
699034003459	RNA binding site [nucleotide binding]; other site
699034003460	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cd00164
699034003461	RNA binding site [nucleotide binding]; other site
699034003462	putative hydrolase; Validated; Region: PRK09248
699034003463	Polymerase and Histidinol Phosphatase domain of Ycdx like; Region: PHP_HisPPase_Ycdx_like; cd07437
699034003464	active site
699034003465	2-isopropylmalate synthase; Validated; Region: PRK03739
699034003466	Mycobacterium tuberculosis LeuA3 and related proteins, N-terminal catalytic TIM barrel domain; Region: DRE_TIM_LeuA; cd07942
699034003467	active site
699034003468	catalytic residues [active]
699034003469	metal binding site [ion binding]; metal-binding site
699034003470	LeuA allosteric (dimerisation) domain; Region: LeuA_dimer; smart00917
699034003471	3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate; Region: IPMI; cd01583
699034003472	substrate binding site [chemical binding]; other site
699034003473	ligand binding site [chemical binding]; other site
699034003474	Aconatase-like swivel domain of 3-isopropylmalate dehydratase and related uncharacterized proteins. 3-isopropylmalate dehydratase catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate...; Region: IPMI_Swivel; cd01577
699034003475	substrate binding site [chemical binding]; other site
699034003476	3-isopropylmalate dehydrogenase; Provisional; Region: PRK00772
699034003477	PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria.  Although orthologs of PaaI exist in archaea and eukaryotes, their function has not...; Region: PaaI_thioesterase; cd03443
699034003478	CoenzymeA binding site [chemical binding]; other site
699034003479	subunit interaction site [polypeptide binding]; other site
699034003480	PHB binding site; other site
699034003481	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
699034003482	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
699034003483	catalytic residue [active]
699034003484	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
699034003485	Phosphoglycerate dehydrogenase (PGDH) NAD-binding and catalytic domains; Region: PGDH_2; cd05303
699034003486	putative ligand binding site [chemical binding]; other site
699034003487	NAD binding site [chemical binding]; other site
699034003488	dimerization interface [polypeptide binding]; other site
699034003489	catalytic site [active]
699034003490	Protein of unknown function (DUF1015); Region: DUF1015; pfam06245
699034003491	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
699034003492	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
699034003493	putative active site [active]
699034003494	heme pocket [chemical binding]; other site
699034003495	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
699034003496	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
699034003497	putative active site [active]
699034003498	heme pocket [chemical binding]; other site
699034003499	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
699034003500	heme pocket [chemical binding]; other site
699034003501	putative active site [active]
699034003502	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
699034003503	metal binding site [ion binding]; metal-binding site
699034003504	active site
699034003505	I-site; other site
699034003506	FOG: GAF domain [Signal transduction mechanisms]; Region: FhlA; COG2203
699034003507	Radical SAM N-terminal; Region: Radical_SAM_N; pfam08497
699034003508	hypothetical protein; Provisional; Region: PRK00955
699034003509	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
699034003510	Domain of unknown function (DUF3362); Region: DUF3362; pfam11842
699034003511	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
699034003512	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; cl19131
699034003513	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
699034003514	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034003515	dimer interface [polypeptide binding]; other site
699034003516	conserved gate region; other site
699034003517	putative PBP binding loops; other site
699034003518	ABC-ATPase subunit interface; other site
699034003519	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034003520	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
699034003521	Walker A/P-loop; other site
699034003522	ATP binding site [chemical binding]; other site
699034003523	Q-loop/lid; other site
699034003524	ABC transporter signature motif; other site
699034003525	Walker B; other site
699034003526	D-loop; other site
699034003527	H-loop/switch region; other site
699034003528	This CD includes cysteinyl-tRNA(Pro) deacylases from Haemophilus influenzae and Escherichia coli and other related bacterial proteins. These trans-acting, single-domain proteins are homologs of ProX and also the cis-acting prolyl-tRNA synthetase (ProRS)...; Region: YbaK_deacylase; cd00002
699034003529	putative deacylase active site [active]
699034003530	fumarate hydratase; Provisional; Region: PRK06246
699034003531	Fumarase C-terminus; Region: Fumerase_C; cl00795
699034003532	Malic enzyme [Energy production and conversion]; Region: SfcA; COG0281
699034003533	Malic enzyme, N-terminal domain; Region: malic; pfam00390
699034003534	NAD(P) binding domain of malic enzyme (ME), subgroup 2; Region: NAD_bind_2_malic_enz; cd05311
699034003535	putative NAD(P) binding site [chemical binding]; other site
699034003536	Putative zinc ribbon domain; Region: Zn_ribbon_2; pfam12674
699034003537	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034003538	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034003539	active site
699034003540	phosphorylation site [posttranslational modification]
699034003541	intermolecular recognition site; other site
699034003542	dimerization interface [polypeptide binding]; other site
699034003543	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034003544	DNA binding site [nucleotide binding]
699034003545	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034003546	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034003547	dimer interface [polypeptide binding]; other site
699034003548	phosphorylation site [posttranslational modification]
699034003549	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034003550	ATP binding site [chemical binding]; other site
699034003551	Mg2+ binding site [ion binding]; other site
699034003552	G-X-G motif; other site
699034003553	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
699034003554	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
699034003555	Walker A/P-loop; other site
699034003556	ATP binding site [chemical binding]; other site
699034003557	Q-loop/lid; other site
699034003558	ABC transporter signature motif; other site
699034003559	Walker B; other site
699034003560	D-loop; other site
699034003561	H-loop/switch region; other site
699034003562	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
699034003563	FtsX-like permease family; Region: FtsX; pfam02687
699034003564	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
699034003565	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
699034003566	FtsX-like permease family; Region: FtsX; pfam02687
699034003567	Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only]; Region: COG2996
699034003568	S1 domain; Region: S1_2; pfam13509
699034003569	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
699034003570	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
699034003571	DNA-binding site [nucleotide binding]; DNA binding site
699034003572	UTRA domain; Region: UTRA; pfam07702
699034003573	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
699034003574	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
699034003575	active site
699034003576	dimer interface [polypeptide binding]; other site
699034003577	GlcN6P_deaminase: Glucosamine-6-phosphate (GlcN6P) deaminase subfamily; GlcN6P deaminase catalyzes the reversible conversion of GlcN6P to D-fructose-6-phosphate (Fru6P) and ammonium. The reaction is an aldo-keto isomerization coupled with an amination or...; Region: GlcN6P_deaminase; cd01399
699034003578	active site
699034003579	trimer interface [polypeptide binding]; other site
699034003580	allosteric site; other site
699034003581	active site lid [active]
699034003582	hexamer (dimer of trimers) interface [polypeptide binding]; other site
699034003583	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034003584	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034003585	active site
699034003586	phosphorylation site [posttranslational modification]
699034003587	intermolecular recognition site; other site
699034003588	dimerization interface [polypeptide binding]; other site
699034003589	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034003590	DNA binding site [nucleotide binding]
699034003591	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034003592	HAMP domain; Region: HAMP; pfam00672
699034003593	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034003594	dimer interface [polypeptide binding]; other site
699034003595	phosphorylation site [posttranslational modification]
699034003596	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034003597	ATP binding site [chemical binding]; other site
699034003598	Mg2+ binding site [ion binding]; other site
699034003599	G-X-G motif; other site
699034003600	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
699034003601	PAS fold; Region: PAS_3; pfam08447
699034003602	putative active site [active]
699034003603	heme pocket [chemical binding]; other site
699034003604	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
699034003605	metal binding site [ion binding]; metal-binding site
699034003606	active site
699034003607	I-site; other site
699034003608	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
699034003609	Helix-Turn-Helix DNA binding domain of the BltR transcription regulator; Region: HTH_BltR; cd04782
699034003610	DNA binding residues [nucleotide binding]
699034003611	dimer interface [polypeptide binding]; other site
699034003612	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
699034003613	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
699034003614	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
699034003615	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034003616	Walker A/P-loop; other site
699034003617	ATP binding site [chemical binding]; other site
699034003618	Q-loop/lid; other site
699034003619	ABC transporter signature motif; other site
699034003620	Walker B; other site
699034003621	D-loop; other site
699034003622	H-loop/switch region; other site
699034003623	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
699034003624	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
699034003625	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
699034003626	Walker A/P-loop; other site
699034003627	ATP binding site [chemical binding]; other site
699034003628	Q-loop/lid; other site
699034003629	ABC transporter signature motif; other site
699034003630	Walker B; other site
699034003631	D-loop; other site
699034003632	H-loop/switch region; other site
699034003633	Polyphosphate(polyP) polymerase domain of yeast vacuolar transport chaperone (VTC) proteins VTC-2, -3 and- 4, and similar proteins; Region: PolyPPase_VTC_like; cd07750
699034003634	putative metal binding residues [ion binding]; other site
699034003635	signature motif; other site
699034003636	dimer interface [polypeptide binding]; other site
699034003637	active site
699034003638	polyP binding site; other site
699034003639	substrate binding site [chemical binding]; other site
699034003640	acceptor-phosphate pocket; other site
699034003641	Uncharacterized membrane protein [Function unknown]; Region: SapB; COG1285
699034003642	CotH protein; Region: CotH; pfam08757
699034003643	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
699034003644	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
699034003645	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
699034003646	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034003647	non-specific DNA binding site [nucleotide binding]; other site
699034003648	salt bridge; other site
699034003649	sequence-specific DNA binding site [nucleotide binding]; other site
699034003650	Cupin domain; Region: Cupin_2; pfam07883
699034003651	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
699034003652	ATP-binding cassette domain of the polyamine transporter; Region: ABC_PotA_N; cd03300
699034003653	Walker A/P-loop; other site
699034003654	ATP binding site [chemical binding]; other site
699034003655	Q-loop/lid; other site
699034003656	ABC transporter signature motif; other site
699034003657	Walker B; other site
699034003658	D-loop; other site
699034003659	H-loop/switch region; other site
699034003660	TOBE domain; Region: TOBE_2; pfam08402
699034003661	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
699034003662	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034003663	dimer interface [polypeptide binding]; other site
699034003664	conserved gate region; other site
699034003665	putative PBP binding loops; other site
699034003666	ABC-ATPase subunit interface; other site
699034003667	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
699034003668	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034003669	dimer interface [polypeptide binding]; other site
699034003670	conserved gate region; other site
699034003671	putative PBP binding loops; other site
699034003672	ABC-ATPase subunit interface; other site
699034003673	Spermidine/putrescine-binding periplasmic protein [Amino acid transport and metabolism]; Region: PotD; COG0687
699034003674	c-di-GMP synthetase (diguanylate cyclase, GGDEF domain) [Signal    transduction mechanisms]; Region: COG2199
699034003675	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
699034003676	metal binding site [ion binding]; metal-binding site
699034003677	active site
699034003678	I-site; other site
699034003679	Putative NodB-like catalytic domain of uncharacterized proteins found in bacteria; Region: CE4_COG5298; cd10923
699034003680	NodB motif; other site
699034003681	putative active site [active]
699034003682	putative catalytic site [active]
699034003683	putative Zn binding site [ion binding]; other site
699034003684	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
699034003685	CESA_like is  the cellulose synthase superfamily; Region: CESA_like; cd06423
699034003686	DXD motif; other site
699034003687	Bacterial cellulose synthase subunit; Region: BcsB; pfam03170
699034003688	UDP-N-acetylglucosamine 2-epimerase; Region: wecB; TIGR00236
699034003689	Bacterial members of the UDP-N-Acetylglucosamine (GlcNAc) 2-Epimerase  family are known to catalyze the reversible interconversion of UDP-GlcNAc and UDP-N-acetylmannosamine (UDP-ManNAc). The enzyme serves to produce an activated form of ManNAc residues; Region: GT1_UDP-GlcNAc_2-Epimerase; cd03786
699034003690	active site
699034003691	homodimer interface [polypeptide binding]; other site
699034003692	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; cl17361
699034003693	potential RNA of insufficient length (23S ribosomal RNA)
699034003694	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034003695	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034003696	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034003697	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
699034003698	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
699034003699	active site
699034003700	metal binding site [ion binding]; metal-binding site
699034003701	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034003702	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034003703	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034003704	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
699034003705	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
699034003706	active site
699034003707	metal binding site [ion binding]; metal-binding site
699034003708	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
699034003709	Part of AAA domain; Region: AAA_19; pfam13245
699034003710	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; cl19402
699034003711	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
699034003712	helicase-exonuclease AddAB, AddB subunit; Region: addB_Gpos; TIGR02773
699034003713	Exodeoxyribonuclease V, gamma subunit; Region: Exonuc_V_gamma; cl19914
699034003714	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
699034003715	helicase-exonuclease AddAB, AddA subunit, Firmicutes type; Region: addA_Gpos; TIGR02785
699034003716	Part of AAA domain; Region: AAA_19; pfam13245
699034003717	UvrD-like helicase C-terminal domain; Region: UvrD_C_2; pfam13538
699034003718	PD-(D/E)XK nuclease superfamily; Region: PDDEXK_1; pfam12705
699034003719	DNA repair exonuclease [DNA replication, recombination, and repair]; Region: SbcD; COG0420
699034003720	Mre11 nuclease, N-terminal metallophosphatase domain; Region: MPP_Mre11_N; cd00840
699034003721	active site
699034003722	metal binding site [ion binding]; metal-binding site
699034003723	DNA binding site [nucleotide binding]
699034003724	Type 5 capsule protein repressor C-terminal domain; Region: SbcD_C; pfam12320
699034003725	exonuclease SbcC; Region: sbcc; TIGR00618
699034003726	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034003727	Walker A/P-loop; other site
699034003728	ATP binding site [chemical binding]; other site
699034003729	Q-loop/lid; other site
699034003730	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034003731	ABC transporter signature motif; other site
699034003732	Walker B; other site
699034003733	D-loop; other site
699034003734	H-loop/switch region; other site
699034003735	Domain of unknown function DUF21; Region: DUF21; pfam01595
699034003736	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
699034003737	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
699034003738	Transporter associated domain; Region: CorC_HlyC; smart01091
699034003739	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; cl00465
699034003740	peptidase T-like protein; Region: PepT-like; TIGR01883
699034003741	M20 Peptidase T specifically cleaves tripeptides; Region: M20_peptT; cd03892
699034003742	metal binding site [ion binding]; metal-binding site
699034003743	dimer interface [polypeptide binding]; other site
699034003744	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034003745	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034003746	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034003747	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
699034003748	active site
699034003749	metal binding site [ion binding]; metal-binding site
699034003750	homotetramer interface [polypeptide binding]; other site
699034003751	NAD kinase [Coenzyme metabolism]; Region: nadF; COG0061
699034003752	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
699034003753	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
699034003754	Walker A/P-loop; other site
699034003755	ATP binding site [chemical binding]; other site
699034003756	Q-loop/lid; other site
699034003757	ABC transporter signature motif; other site
699034003758	Walker B; other site
699034003759	D-loop; other site
699034003760	H-loop/switch region; other site
699034003761	ABC-2 family transporter protein; Region: ABC2_membrane_5; pfam13346
699034003762	This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens  ProX Ala-tRNA(Pro)...; Region: ProX_deacylase; cd04333
699034003763	putative deacylase active site [active]
699034003764	Acyl-CoA dehydrogenases [Lipid metabolism]; Region: CaiA; COG1960
699034003765	Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases; Region: SCAD_SBCAD; cd01158
699034003766	FAD binding site [chemical binding]; other site
699034003767	homotetramer interface [polypeptide binding]; other site
699034003768	substrate binding pocket [chemical binding]; other site
699034003769	catalytic base [active]
699034003770	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
699034003771	Ligand binding site [chemical binding]; other site
699034003772	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
699034003773	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
699034003774	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
699034003775	3-hydroxybutyryl-CoA dehydratase; Validated; Region: PRK05809
699034003776	Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase; Region: crotonase-like; cd06558
699034003777	substrate binding site [chemical binding]; other site
699034003778	oxyanion hole (OAH) forming residues; other site
699034003779	trimer interface [polypeptide binding]; other site
699034003780	3-hydroxybutyryl-CoA dehydrogenase; Validated; Region: PRK05808
699034003781	3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; Region: 3HCDH_N; pfam02737
699034003782	3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; Region: 3HCDH; pfam00725
699034003783	putative acyltransferase; Provisional; Region: PRK05790
699034003784	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
699034003785	dimer interface [polypeptide binding]; other site
699034003786	active site
699034003787	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
699034003788	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
699034003789	active site
699034003790	37-kD nucleoid-associated bacterial protein; Region: NA37; pfam04245
699034003791	acyl carrier protein; Provisional; Region: acpP; PRK00982
699034003792	Transcriptional regulators [Transcription]; Region: PurR; COG1609
699034003793	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
699034003794	DNA binding site [nucleotide binding]
699034003795	domain linker motif; other site
699034003796	Ligand-binding domain of the catabolite control protein A (CcpA), which functions as the major transcriptional regulator of carbon catabolite repression/regulation; Region: PBP1_CcpA_like; cd06298
699034003797	dimerization interface [polypeptide binding]; other site
699034003798	effector binding site; other site
699034003799	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
699034003800	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
699034003801	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
699034003802	histidinol phosphate phosphatase, HisJ family; Region: hisJ_fam; TIGR01856
699034003803	active site
699034003804	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
699034003805	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
699034003806	DNA-binding site [nucleotide binding]; DNA binding site
699034003807	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
699034003808	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034003809	homodimer interface [polypeptide binding]; other site
699034003810	catalytic residue [active]
699034003811	Bacterial protein of unknown function (DUF896); Region: DUF896; pfam05979
699034003812	M18 Peptidase Aminopeptidase I; Region: M18_API; cd05659
699034003813	oligomer interface [polypeptide binding]; other site
699034003814	putative active site [active]
699034003815	metal binding site [ion binding]; metal-binding site
699034003816	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
699034003817	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
699034003818	DNA-binding site [nucleotide binding]; DNA binding site
699034003819	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
699034003820	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
699034003821	active pocket/dimerization site; other site
699034003822	active site
699034003823	phosphorylation site [posttranslational modification]
699034003824	BtpA family; Region: BtpA; cl00440
699034003825	PTS_IIB, PTS system, Mannose/sorbose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_man; cd00001
699034003826	active site
699034003827	phosphorylation site [posttranslational modification]
699034003828	PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609
699034003829	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
699034003830	Transcriptional regulator [Transcription]; Region: LysR; COG0583
699034003831	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
699034003832	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cl11398
699034003833	dimerization interface [polypeptide binding]; other site
699034003834	Molybdopterin biosynthesis enzyme [Coenzyme metabolism]; Region: MoeA; COG0303
699034003835	MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and...; Region: MoeA; cd00887
699034003836	dimer interface [polypeptide binding]; other site
699034003837	putative functional site; other site
699034003838	putative MPT binding site; other site
699034003839	Molybdenum is an essential trace element in the form of molybdenum cofactor (Moco) which is associated with the metabolism of nitrogen, carbon and sulfur by redox active enzymes. In E. coli, the synthesis of Moco involves genes from several loci: moa; Region: MobB; cd03116
699034003840	Walker A motif; other site
699034003841	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
699034003842	active site
699034003843	P-loop; other site
699034003844	phosphorylation site [posttranslational modification]
699034003845	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
699034003846	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
699034003847	ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; Region: ABCC_MsbA; cd03251
699034003848	Walker A/P-loop; other site
699034003849	ATP binding site [chemical binding]; other site
699034003850	Q-loop/lid; other site
699034003851	ABC transporter signature motif; other site
699034003852	Walker B; other site
699034003853	D-loop; other site
699034003854	H-loop/switch region; other site
699034003855	Sodium/glutamate symporter; Region: Glt_symporter; cl19414
699034003856	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
699034003857	M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_subfamily5; cd08019
699034003858	metal binding site [ion binding]; metal-binding site
699034003859	putative dimer interface [polypeptide binding]; other site
699034003860	zinc transporter ZupT; Provisional; Region: PRK04201
699034003861	Protein of unknown function (DUF2812); Region: DUF2812; pfam11193
699034003862	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
699034003863	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034003864	active site
699034003865	phosphorylation site [posttranslational modification]
699034003866	intermolecular recognition site; other site
699034003867	dimerization interface [polypeptide binding]; other site
699034003868	LytTr DNA-binding domain; Region: LytTR; smart00850
699034003869	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
699034003870	GHKL domain; Region: HATPase_c_5; pfam14501
699034003871	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
699034003872	Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL; cl09939
699034003873	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
699034003874	anaerobic ribonucleotide reductase-activating protein; Provisional; Region: nrdG; cl15804
699034003875	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
699034003876	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl18962
699034003877	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
699034003878	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034003879	non-specific DNA binding site [nucleotide binding]; other site
699034003880	salt bridge; other site
699034003881	sequence-specific DNA binding site [nucleotide binding]; other site
699034003882	Cupin domain; Region: Cupin_2; pfam07883
699034003883	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
699034003884	Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409
699034003885	putative active site [active]
699034003886	putative metal binding site [ion binding]; other site
699034003887	Coenzyme PQQ synthesis protein D (PqqD); Region: PqqD; cl05126
699034003888	Iron-sulfur cluster-binding domain; Region: SPASM; pfam13186
699034003889	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514
699034003890	FMN binding site [chemical binding]; other site
699034003891	dimer interface [polypeptide binding]; other site
699034003892	Nitroreductase family; Region: Nitroreductase; pfam00881
699034003893	FMN binding site [chemical binding]; other site
699034003894	dimer interface [polypeptide binding]; other site
699034003895	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
699034003896	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
699034003897	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3708
699034003898	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034003899	non-specific DNA binding site [nucleotide binding]; other site
699034003900	salt bridge; other site
699034003901	sequence-specific DNA binding site [nucleotide binding]; other site
699034003902	Transposase IS200 like; Region: Y1_Tnp; cl00848
699034003903	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
699034003904	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
699034003905	Probable transposase; Region: OrfB_IS605; pfam01385
699034003906	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
699034003907	DHHW protein; Region: DHHW; pfam14286
699034003908	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
699034003909	DNA polymerase I; Provisional; Region: PRK05755
699034003910	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
699034003911	active site
699034003912	metal binding site 1 [ion binding]; metal-binding site
699034003913	putative 5' ssDNA interaction site; other site
699034003914	metal binding site 3; metal-binding site
699034003915	metal binding site 2 [ion binding]; metal-binding site
699034003916	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
699034003917	putative DNA binding site [nucleotide binding]; other site
699034003918	putative metal binding site [ion binding]; other site
699034003919	inactive DEDDy 3'-5' exonuclease domain of Bacillus stearothermophilus DNA polymerase I and similar family-A DNA polymerases; Region: DNA_polA_I_Bacillus_like_exo; cd06140
699034003920	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
699034003921	active site
699034003922	DNA binding site [nucleotide binding]
699034003923	catalytic site [active]
699034003924	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
699034003925	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
699034003926	CoA-binding site [chemical binding]; other site
699034003927	ATP-binding [chemical binding]; other site
699034003928	Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) [Cell envelope biogenesis, outer membrane]; Region: MltE; COG0741
699034003929	Lytic Transglycosylase (LT)  and Goose Egg White Lysozyme (GEWL) domain. Members include the soluble and insoluble membrane-bound LTs in bacteria, the LTs in bacteriophage lambda, as well as, the eukaryotic "goose-type" lysozymes (GEWL).  LTs...; Region: LT_GEWL; cd00254
699034003930	N-acetyl-D-glucosamine binding site [chemical binding]; other site
699034003931	catalytic residue [active]
699034003932	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
699034003933	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cd00995
699034003934	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
699034003935	metal-binding site [ion binding]
699034003936	Glyoxalase I catalyzes the isomerization of the hemithioacetal, formed by a 2-oxoaldehyde and glutathione, to S-D-lactoylglutathione; Region: Glyoxalase_I; cd07233
699034003937	dimer interface [polypeptide binding]; other site
699034003938	active site
699034003939	metal binding site [ion binding]; metal-binding site
699034003940	glutathione binding site [chemical binding]; other site
699034003941	Bacterial SH3 domain; Region: SH3_3; pfam08239
699034003942	Bacterial SH3 domain; Region: SH3_3; pfam08239
699034003943	Bacterial SH3 domain homologues; Region: SH3b; smart00287
699034003944	Src Homology 3 domain superfamily; Region: SH3; cd00174
699034003945	peptide ligand binding site [polypeptide binding]; other site
699034003946	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
699034003947	NlpC/P60 family; Region: NLPC_P60; pfam00877
699034003948	electron transport complex, RnfABCDGE type, C subunit; Region: rnfC; TIGR01945
699034003949	RnfC Barrel sandwich hybrid domain; Region: RnfC_N; pfam13375
699034003950	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
699034003951	SLBB domain; Region: SLBB; pfam10531
699034003952	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
699034003953	NQR2, RnfD, RnfE family; Region: NQR2_RnfD_RnfE; pfam03116
699034003954	FMN-binding domain; Region: FMN_bind; cl01081
699034003955	electron transport complex RsxE subunit; Provisional; Region: PRK12405
699034003956	Rnf-Nqr subunit, membrane protein; Region: Rnf-Nqr; cl00597
699034003957	ferredoxin; Validated; Region: PRK07118
699034003958	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
699034003959	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
699034003960	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
699034003961	4Fe-4S dicluster domain; Region: Fer4_10; pfam13237
699034003962	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
699034003963	active site
699034003964	dimer interface [polypeptide binding]; other site
699034003965	DNA repair proteins [DNA replication, recombination, and repair]; Region: RadC; COG2003
699034003966	Mov34/MPN/PAD-1 family; Region: MPN_DUF2466; cd08071
699034003967	MPN+ (JAMM) motif; other site
699034003968	Zinc-binding site [ion binding]; other site
699034003969	rod shape-determining protein MreB; Provisional; Region: PRK13927
699034003970	MreB and similar proteins; Region: MreB_like; cd10225
699034003971	nucleotide binding site [chemical binding]; other site
699034003972	Mg binding site [ion binding]; other site
699034003973	putative protofilament interaction site [polypeptide binding]; other site
699034003974	RodZ interaction site [polypeptide binding]; other site
699034003975	rod shape-determining protein MreC; Provisional; Region: PRK13922
699034003976	penicillin-binding protein 2; Region: pbp2_mrdA; TIGR03423
699034003977	Penicillin-binding Protein dimerization domain; Region: PBP_dimer; pfam03717
699034003978	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
699034003979	septum formation inhibitor; Reviewed; Region: minC; PRK00513
699034003980	Septum formation inhibitor MinC, C-terminal domain; Region: MinC_C; pfam03775
699034003981	Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning]; Region: MinD; COG2894
699034003982	Bacterial cell division requires the formation of a septum at mid-cell. The site is determined by the min operon products MinC, MinD and MinE. MinC is a nonspecific inhibitor of the septum protein FtsZ. MinE is the supressor of MinC. MinD plays a pivotal...; Region: MinD; cd02036
699034003983	P-loop; other site
699034003984	ADP binding residues [chemical binding]; other site
699034003985	Switch I; other site
699034003986	Switch II; other site
699034003987	cell division topological specificity factor MinE; Provisional; Region: PRK13987
699034003988	rod shape-determining protein RodA; Region: rodA_shape; TIGR02210
699034003989	Methylglyoxal synthase catalyzes the enolization of dihydroxyacetone phosphate (DHAP) to produce methylglyoxal. The first part of the catalytic mechanism is believed to be similar to TIM (triosephosphate isomerase) in that both enzymes utilize DHAP to...; Region: MGS; cd01422
699034003990	active site
699034003991	dimer interfaces [polypeptide binding]; other site
699034003992	catalytic residues [active]
699034003993	Transcriptional regulator PadR-like family; Region: PadR; cl17335
699034003994	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
699034003995	Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426
699034003996	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
699034003997	NADPH-dependent FMN reductase; Region: FMN_red; cl00438
699034003998	radical SAM family uncharacterized protein; Region: rSAM_fuse_unch; TIGR03960
699034003999	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
699034004000	B12 binding site [chemical binding]; other site
699034004001	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
699034004002	FeS/SAM binding site; other site
699034004003	radical SAM-linked protein; Region: sam_1_link_chp; TIGR03936
699034004004	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
699034004005	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
699034004006	homodimer interface [polypeptide binding]; other site
699034004007	oligonucleotide binding site [chemical binding]; other site
699034004008	Ribonuclease E/G family; Region: RNase_E_G; pfam10150
699034004009	50S ribosomal protein L21; Validated; Region: rplU; PRK05573
699034004010	Protein of unknown function (DUF464); Region: DUF464; pfam04327
699034004011	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
699034004012	GTPase CgtA; Reviewed; Region: obgE; PRK12297
699034004013	GTP1/OBG; Region: GTP1_OBG; pfam01018
699034004014	Obg GTPase; Region: Obg; cd01898
699034004015	G1 box; other site
699034004016	GTP/Mg2+ binding site [chemical binding]; other site
699034004017	Switch I region; other site
699034004018	G2 box; other site
699034004019	G3 box; other site
699034004020	Switch II region; other site
699034004021	G4 box; other site
699034004022	G5 box; other site
699034004023	Domain of unknown function (DUF1967); Region: DUF1967; pfam09269
699034004024	Predicted RNA-binding protein containing KH domain, possibly ribosomal protein [Translation, ribosomal structure and biogenesis]; Region: COG1534
699034004025	Homoserine dehydrogenase [Amino acid transport and metabolism]; Region: ThrA; COG0460
699034004026	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
699034004027	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
699034004028	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
699034004029	active site
699034004030	DNA binding site [nucleotide binding]
699034004031	Int/Topo IB signature motif; other site
699034004032	sporulation integral membrane protein YlbJ; Region: spore_ylbJ; TIGR02871
699034004033	Nucleoside recognition; Region: Gate; pfam07670
699034004034	Transcriptional regulators [Transcription]; Region: FadR; COG2186
699034004035	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
699034004036	DNA-binding site [nucleotide binding]; DNA binding site
699034004037	This entry represents the C-terminal ligand binding domain of many members of the GntR family; Region: FCD; smart00895
699034004038	Domain of unknown function (DUF2088); Region: DUF2088; cl15406
699034004039	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_beta; cd01714
699034004040	Ligand binding site [chemical binding]; other site
699034004041	Ferredoxin [Energy production and conversion]; Region: NapF; COG1145
699034004042	Electron transfer flavoprotein, alpha subunit [Energy production and conversion]; Region: FixB; COG2025
699034004043	The electron transfer flavoprotein (ETF) serves as a specific electron acceptor for various mitochondrial dehydrogenases. ETF transfers electrons to the main respiratory chain via ETF-ubiquinone oxidoreductase. ETF is an heterodimer that consists of an...; Region: ETF_alpha; cd01715
699034004044	Electron transfer flavoprotein FAD-binding domain; Region: ETF_alpha; pfam00766
699034004045	FAD/FMN-containing dehydrogenases [Energy production and conversion]; Region: GlcD; COG0277
699034004046	FAD binding domain; Region: FAD_binding_4; pfam01565
699034004047	FAD linked oxidases, C-terminal domain; Region: FAD-oxidase_C; pfam02913
699034004048	hypothetical protein; Provisional; Region: PRK13670
699034004049	HIGH Nucleotidyl Transferase; Region: HIGH_NTase1; cl17673
699034004050	acetate kinase A/propionate kinase 2; Reviewed; Region: PRK00180
699034004051	Uncharacterized ACR, COG1399; Region: DUF177; pfam02620
699034004052	50S ribosomal protein L32; Reviewed; Region: rpmF; PRK12286
699034004053	fatty acid biosynthesis transcriptional regulator; Provisional; Region: PRK04424
699034004054	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
699034004055	The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated...; Region: hot_dog; cl00509
699034004056	putative phosphate acyltransferase; Provisional; Region: PRK05331
699034004057	3-oxoacyl-(acyl carrier protein) synthase III; Reviewed; Region: PRK09352
699034004058	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
699034004059	dimer interface [polypeptide binding]; other site
699034004060	active site
699034004061	CoA binding pocket [chemical binding]; other site
699034004062	putative enoyl-[acyl-carrier-protein] reductase II; Region: enACPred_II; TIGR03151
699034004063	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
699034004064	FMN binding site [chemical binding]; other site
699034004065	substrate binding site [chemical binding]; other site
699034004066	putative catalytic residue [active]
699034004067	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
699034004068	3-ketoacyl-(acyl-carrier-protein) reductase; Validated; Region: fabG; PRK05557
699034004069	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
699034004070	NAD(P) binding site [chemical binding]; other site
699034004071	homotetramer interface [polypeptide binding]; other site
699034004072	homodimer interface [polypeptide binding]; other site
699034004073	active site
699034004074	acyl carrier protein; Provisional; Region: acpP; PRK00982
699034004075	beta-ketoacyl-acyl-carrier-protein synthase II; Region: fabF; TIGR03150
699034004076	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
699034004077	dimer interface [polypeptide binding]; other site
699034004078	active site
699034004079	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
699034004080	metal binding site [ion binding]; metal-binding site
699034004081	active site
699034004082	I-site; other site
699034004083	PAS domain; Region: PAS; smart00091
699034004084	PAS domain S-box; Region: sensory_box; TIGR00229
699034004085	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034004086	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
699034004087	Walker A motif; other site
699034004088	ATP binding site [chemical binding]; other site
699034004089	Walker B motif; other site
699034004090	arginine finger; other site
699034004091	TSCPD domain; Region: TSCPD; cl14834
699034004092	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
699034004093	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
699034004094	catalytic triad [active]
699034004095	amino acid transporter; Region: 2A0306; TIGR00909
699034004096	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
699034004097	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
699034004098	Coenzyme A binding pocket [chemical binding]; other site
699034004099	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
699034004100	Firmicute fructose-1,6-bisphosphatase; Region: FBPase_2; pfam06874
699034004101	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl18944
699034004102	stage III sporulation protein AA; Region: spore_III_AA; TIGR02858
699034004103	Stage III sporulation protein AB (spore_III_AB); Region: Spore_III_AB; pfam09548
699034004104	Stage III sporulation protein AC/AD protein family; Region: SpoIIIAC; cl05961
699034004105	Stage III sporulation protein AC/AD protein family; Region: SpoIIIAC; cl05961
699034004106	Stage III sporulation protein AE (spore_III_AE); Region: Spore_III_AE; pfam09546
699034004107	Stage III sporulation protein AF (Spore_III_AF); Region: Spore_III_AF; pfam09581
699034004108	stage III sporulation protein AG; Region: spore_III_AG; TIGR02830
699034004109	SpoIIIAH-like protein; Region: SpoIIIAH; pfam12685
699034004110	Asp23 family; Region: Asp23; pfam03780
699034004111	transcription antitermination factor NusB; Region: nusB; TIGR01951
699034004112	metallohydrolase, glycoprotease/Kae1 family; Region: gcp_kae1; TIGR00329
699034004113	exodeoxyribonuclease VII large subunit; Reviewed; Region: xseA; PRK00286
699034004114	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
699034004115	generic binding surface II; other site
699034004116	generic binding surface I; other site
699034004117	Exonuclease VII small subunit; Region: Exonuc_VII_S; pfam02609
699034004118	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
699034004119	substrate binding pocket [chemical binding]; other site
699034004120	chain length determination region; other site
699034004121	substrate-Mg2+ binding site; other site
699034004122	catalytic residues [active]
699034004123	aspartate-rich region 1; other site
699034004124	active site lid residues [active]
699034004125	aspartate-rich region 2; other site
699034004126	Divergent PAP2 family; Region: DUF212; pfam02681
699034004127	1-deoxy-D-xylulose-5-phosphate synthase; Provisional; Region: PRK05444
699034004128	Thiamine pyrophosphate (TPP) family, DXS subfamily, TPP-binding module; 1-Deoxy-D-xylulose-5-phosphate synthase (DXS) is a regulatory enzyme of the mevalonate-independent pathway involved in terpenoid biosynthesis. Terpeniods are plant natural products...; Region: TPP_DXS; cd02007
699034004129	TPP-binding site; other site
699034004130	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
699034004131	PYR/PP interface [polypeptide binding]; other site
699034004132	dimer interface [polypeptide binding]; other site
699034004133	TPP binding site [chemical binding]; other site
699034004134	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
699034004135	Predicted rRNA methylase [Translation, ribosomal structure and biogenesis]; Region: COG1189
699034004136	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
699034004137	RNA binding surface [nucleotide binding]; other site
699034004138	FtsJ-like methyltransferase; Region: FtsJ; pfam01728
699034004139	ATPase involved in DNA repair [DNA replication, recombination, and repair]; Region: RecN; COG0497
699034004140	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
699034004141	Walker A/P-loop; other site
699034004142	ATP binding site [chemical binding]; other site
699034004143	Q-loop/lid; other site
699034004144	ATP-binding cassette domain of RecN; Region: ABC_RecN; cd03241
699034004145	ABC transporter signature motif; other site
699034004146	Walker B; other site
699034004147	D-loop; other site
699034004148	H-loop/switch region; other site
699034004149	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
699034004150	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
699034004151	Coenzyme A binding pocket [chemical binding]; other site
699034004152	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
699034004153	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
699034004154	Coenzyme A binding pocket [chemical binding]; other site
699034004155	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
699034004156	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
699034004157	SpoIVB peptidase S55; Region: Peptidase_S55; pfam05580
699034004158	sporulation transcription factor Spo0A; Region: spore_0_A; TIGR02875
699034004159	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034004160	active site
699034004161	phosphorylation site [posttranslational modification]
699034004162	intermolecular recognition site; other site
699034004163	dimerization interface [polypeptide binding]; other site
699034004164	Sporulation initiation factor Spo0A C terminal; Region: Spo0A_C; pfam08769
699034004165	Uncharacterized membrane-anchored protein conserved in bacteria [Function unknown]; Region: COG4825
699034004166	Thiamine pyrophosphokinase; Region: TPK; cd07995
699034004167	active site
699034004168	Thiamine pyrophosphokinase C terminal; Region: TPPK_C; pfam12555
699034004169	Protein of unknown function (DUF3186); Region: DUF3186; pfam11382
699034004170	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
699034004171	DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily; Region: DPM_DPG-synthase_like; cd04179
699034004172	Ligand binding site; other site
699034004173	Putative Catalytic site; other site
699034004174	DXD motif; other site
699034004175	Protein of unknown function (DUF3866); Region: DUF3866; pfam12982
699034004176	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
699034004177	dimer interface [polypeptide binding]; other site
699034004178	ADP-ribose binding site [chemical binding]; other site
699034004179	active site
699034004180	nudix motif; other site
699034004181	metal binding site [ion binding]; metal-binding site
699034004182	Integral membrane protein DUF95; Region: DUF95; cl00572
699034004183	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
699034004184	tyrosine recombinase XerD; Region: recomb_XerD; TIGR02225
699034004185	active site
699034004186	DNA binding site [nucleotide binding]
699034004187	Int/Topo IB signature motif; other site
699034004188	phosphopentomutase; Provisional; Region: PRK05362
699034004189	purine nucleoside phosphorylase; Provisional; Region: PRK08202
699034004190	Purine nucleoside phosphorylase [Nucleotide transport and metabolism]; Region: Pnp; COG0005
699034004191	pyrimidine-nucleoside phosphorylase; Reviewed; Region: PRK06078
699034004192	Glycosyl transferase family, helical bundle domain; Region: Glycos_trans_3N; pfam02885
699034004193	Glycosyl transferase family, a/b domain; Region: Glycos_transf_3; pfam00591
699034004194	Pyrimidine nucleoside phosphorylase C-terminal domain; Region: PYNP_C; smart00941
699034004195	proteins similar to Escherichia coli yceG; Region: yceG_like; cd08010
699034004196	dimerization interface [polypeptide binding]; other site
699034004197	Methyltransferase domain; Region: Methyltransf_31; pfam13847
699034004198	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
699034004199	S-adenosylmethionine binding site [chemical binding]; other site
699034004200	putative protease; Provisional; Region: PRK15452
699034004201	Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones]; Region: COG0826
699034004202	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
699034004203	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
699034004204	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
699034004205	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257
699034004206	DNA binding residues [nucleotide binding]
699034004207	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
699034004208	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
699034004209	catalytic residues [active]
699034004210	catalytic nucleophile [active]
699034004211	Recombinase; Region: Recombinase; pfam07508
699034004212	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
699034004213	NTF2-like N-terminal transpeptidase domain; Region: MecA_N; pfam05223
699034004214	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
699034004215	TPR motif; other site
699034004216	TPR repeat; Region: TPR_11; pfam13414
699034004217	binding surface
699034004218	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034004219	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034004220	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034004221	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
699034004222	Helix-turn-helix domain; Region: HTH_28; pfam13518
699034004223	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
699034004224	Helix-turn-helix domain; Region: HTH_28; pfam13518
699034004225	putative transposase OrfB; Reviewed; Region: PHA02517
699034004226	HTH-like domain; Region: HTH_21; pfam13276
699034004227	Integrase core domain; Region: rve; pfam00665
699034004228	Integrase core domain; Region: rve_2; pfam13333
699034004229	Penicillinase repressor; Region: Penicillinase_R; cl17580
699034004230	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00062
699034004231	VanZ like family; Region: VanZ; pfam04892
699034004232	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
699034004233	elongation factor P; Validated; Region: PRK00529
699034004234	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
699034004235	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
699034004236	RNA binding site [nucleotide binding]; other site
699034004237	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
699034004238	RNA binding site [nucleotide binding]; other site
699034004239	Phage terminase large subunit (GpA); Region: Terminase_GpA; cl19377
699034004240	ribonuclease III; Reviewed; Region: rnc; PRK00102
699034004241	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
699034004242	dimerization interface [polypeptide binding]; other site
699034004243	active site
699034004244	metal binding site [ion binding]; metal-binding site
699034004245	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
699034004246	dsRNA binding site [nucleotide binding]; other site
699034004247	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
699034004248	Radical SAM superfamily; Region: Radical_SAM; pfam04055
699034004249	FeS/SAM binding site; other site
699034004250	chromosome segregation protein SMC, common bacterial type; Region: SMC_prok_B; TIGR02168
699034004251	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
699034004252	Walker A/P-loop; other site
699034004253	ATP binding site [chemical binding]; other site
699034004254	Q-loop/lid; other site
699034004255	SMC proteins Flexible Hinge Domain; Region: SMC_hinge; smart00968
699034004256	ATP-binding cassette domain of barmotin, a member of the SMC protein family; Region: ABC_SMC_barmotin; cd03278
699034004257	ABC transporter signature motif; other site
699034004258	Walker B; other site
699034004259	D-loop; other site
699034004260	H-loop/switch region; other site
699034004261	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cl03075
699034004262	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
699034004263	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
699034004264	SRP54-type protein, GTPase domain; Region: SRP54; smart00962
699034004265	putative DNA-binding protein; Validated; Region: PRK00118
699034004266	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
699034004267	signal recognition particle protein; Provisional; Region: PRK10867
699034004268	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
699034004269	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
699034004270	P loop; other site
699034004271	GTP binding site [chemical binding]; other site
699034004272	Signal peptide binding domain; Region: SRP_SPB; pfam02978
699034004273	30S ribosomal protein S16; Reviewed; Region: rpsP; PRK00040
699034004274	KH domain; Region: KH_4; pfam13083
699034004275	16S rRNA-processing protein RimM; Provisional; Region: rimM; PRK00122
699034004276	RimM N-terminal domain; Region: RimM; pfam01782
699034004277	PRC-barrel domain; Region: PRC; pfam05239
699034004278	tRNA (guanine-N(1)-)-methyltransferase; Reviewed; Region: trmD; PRK00026
699034004279	50S ribosomal protein L19; Provisional; Region: rplS; PRK05338
699034004280	ribosome biogenesis GTP-binding protein YlqF; Region: GTPase_YlqF; TIGR03596
699034004281	Circularly permuted YlqF GTPase; Region: YlqF; cd01856
699034004282	GTP/Mg2+ binding site [chemical binding]; other site
699034004283	G4 box; other site
699034004284	G5 box; other site
699034004285	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cl17170
699034004286	G1 box; other site
699034004287	G1 box; other site
699034004288	GTP/Mg2+ binding site [chemical binding]; other site
699034004289	G2 box; other site
699034004290	Switch I region; other site
699034004291	Switch I region; other site
699034004292	G2 box; other site
699034004293	G3 box; other site
699034004294	G3 box; other site
699034004295	Switch II region; other site
699034004296	Switch II region; other site
699034004297	G4 box; other site
699034004298	Branched-chain amino acid transport protein; Region: Branch_AA_trans; cl00547
699034004299	Branched-chain amino acid transport protein; Region: Branch_AA_trans; cl00547
699034004300	ATP cone domain; Region: ATP-cone; pfam03477
699034004301	Class II ribonucleotide reductase, dimeric form; Region: RNR_II_dimer; cd02888
699034004302	ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Region: NrdJ_Z; TIGR02504
699034004303	active site
699034004304	dimer interface [polypeptide binding]; other site
699034004305	effector binding site; other site
699034004306	Bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
699034004307	RNA/DNA hybrid binding site [nucleotide binding]; other site
699034004308	active site
699034004309	Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809
699034004310	active site
699034004311	substrate binding site [chemical binding]; other site
699034004312	FMN-dependent dehydrogenase; Region: FMN_dh; pfam01070
699034004313	FMN binding site [chemical binding]; other site
699034004314	putative catalytic residues [active]
699034004315	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; cl00588
699034004316	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
699034004317	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
699034004318	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
699034004319	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034004320	Walker A/P-loop; other site
699034004321	ATP binding site [chemical binding]; other site
699034004322	Q-loop/lid; other site
699034004323	ABC transporter signature motif; other site
699034004324	Walker B; other site
699034004325	D-loop; other site
699034004326	H-loop/switch region; other site
699034004327	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
699034004328	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034004329	active site
699034004330	phosphorylation site [posttranslational modification]
699034004331	intermolecular recognition site; other site
699034004332	dimerization interface [polypeptide binding]; other site
699034004333	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
699034004334	DNA binding residues [nucleotide binding]
699034004335	dimerization interface [polypeptide binding]; other site
699034004336	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG4585
699034004337	Histidine kinase; Region: HisKA_3; pfam07730
699034004338	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034004339	ATP binding site [chemical binding]; other site
699034004340	Mg2+ binding site [ion binding]; other site
699034004341	G-X-G motif; other site
699034004342	hypothetical protein; Reviewed; Region: PRK12497
699034004343	Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: COG0606
699034004344	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
699034004345	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034004346	Walker A motif; other site
699034004347	ATP binding site [chemical binding]; other site
699034004348	Walker B motif; other site
699034004349	Magnesium chelatase, subunit ChlI; Region: Mg_chelatase_2; pfam13335
699034004350	Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion]; Region: Smf; COG0758
699034004351	DNA recombination-mediator protein A; Region: DNA_processg_A; pfam02481
699034004352	DNA topoisomerase I; Validated; Region: PRK05582
699034004353	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
699034004354	active site
699034004355	interdomain interaction site; other site
699034004356	putative metal-binding site [ion binding]; other site
699034004357	nucleotide binding site [chemical binding]; other site
699034004358	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
699034004359	domain I; other site
699034004360	DNA binding groove [nucleotide binding]
699034004361	phosphate binding site [ion binding]; other site
699034004362	domain II; other site
699034004363	domain III; other site
699034004364	nucleotide binding site [chemical binding]; other site
699034004365	catalytic site [active]
699034004366	domain IV; other site
699034004367	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
699034004368	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
699034004369	CodY GAF-like domain; Region: CodY; pfam06018
699034004370	transcriptional repressor CodY; Validated; Region: PRK04158
699034004371	CodY helix-turn-helix domain; Region: HTH_CodY; pfam08222
699034004372	recombination factor protein RarA; Reviewed; Region: PRK13342
699034004373	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034004374	Walker A motif; other site
699034004375	ATP binding site [chemical binding]; other site
699034004376	Walker B motif; other site
699034004377	arginine finger; other site
699034004378	MgsA AAA+ ATPase C terminal; Region: MgsA_C; pfam12002
699034004379	Predicted acetyltransferase [General function prediction only]; Region: COG3393
699034004380	GNAT acetyltransferase; Region: GNAT_acetyltran; pfam12746
699034004381	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
699034004382	Coenzyme A binding pocket [chemical binding]; other site
699034004383	Predicted transcriptional regulator [Transcription]; Region: COG1959
699034004384	Rrf2 family protein; Region: rrf2_super; TIGR00738
699034004385	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
699034004386	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
699034004387	catalytic residue [active]
699034004388	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cd06664
699034004389	trimerization site [polypeptide binding]; other site
699034004390	active site
699034004391	Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain [Translation, ribosomal structure and biogenesis]; Region: TrmU; COG0482
699034004392	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
699034004393	Ligand Binding Site [chemical binding]; other site
699034004394	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
699034004395	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
699034004396	motif 1; other site
699034004397	active site
699034004398	motif 2; other site
699034004399	motif 3; other site
699034004400	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
699034004401	DHHA1 domain; Region: DHHA1; pfam02272
699034004402	hypothetical protein; Provisional; Region: PRK05473
699034004403	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl19158
699034004404	Holliday junction resolvase-like protein; Reviewed; Region: PRK00109
699034004405	Protein of unknown function (DUF1292); Region: DUF1292; pfam06949
699034004406	Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators; Region: Fur_like; cd07153
699034004407	metal binding site 2 [ion binding]; metal-binding site
699034004408	putative DNA binding helix; other site
699034004409	metal binding site 1 [ion binding]; metal-binding site
699034004410	dimer interface [polypeptide binding]; other site
699034004411	structural Zn2+ binding site [ion binding]; other site
699034004412	Predicted membrane-bound metal-dependent hydrolase (DUF457); Region: DUF457; pfam04307
699034004413	mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair]; Region: COG0595
699034004414	Metallo-beta-lactamase superfamily; Region: Lactamase_B; pfam00753
699034004415	RNA-metabolizing metallo-beta-lactamase; Region: RMMBL; pfam07521
699034004416	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
699034004417	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl19191
699034004418	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
699034004419	Protein of unknown function (DUF2000); Region: DUF2000; pfam09391
699034004420	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
699034004421	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
699034004422	Uncharacterized homologs of Site-2 protease (S2P), zinc metalloproteases (MEROPS family M50) which cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of the...; Region: S2P-M50_like_1; cd06158
699034004423	Peptidase family M50; Region: Peptidase_M50; pfam02163
699034004424	active site
699034004425	putative substrate binding region [chemical binding]; other site
699034004426	ScpA/B protein; Region: ScpA_ScpB; cl00598
699034004427	Putative transcriptional regulators (Ypuh-like); Region: DUF387; pfam04079
699034004428	Protein of unknown function (DUF2953); Region: DUF2953; pfam11167
699034004429	Sporulation protein YtfJ (Spore_YtfJ); Region: Spore_YtfJ; cl01596
699034004430	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
699034004431	MarR family; Region: MarR_2; pfam12802
699034004432	potential frameshift: common BLAST hit: gi|260686505|ref|YP_003217638.1| leucyl aminopeptidase
699034004433	Integral membrane protein (intg_mem_TP0381); Region: Intg_mem_TP0381; cl02331
699034004434	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in uncharacterized protein from Archaeoglobus fulgidus (Af0060) and its bacterial homologs; Region: NTP-PPase_Af0060_like; cd11533
699034004435	homodimer interface [polypeptide binding]; other site
699034004436	metal binding site [ion binding]; metal-binding site
699034004437	NAD-dependent deacetylase; Provisional; Region: PRK00481
699034004438	Bacterial SH3 domain; Region: SH3_3; pfam08239
699034004439	Bacterial SH3 domain; Region: SH3_3; pfam08239
699034004440	Bacterial SH3 domain; Region: SH3_3; pfam08239
699034004441	Bacterial SH3 domain; Region: SH3_3; pfam08239
699034004442	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; cl17361
699034004443	DNA polymerase III PolC; Validated; Region: polC; PRK00448
699034004444	DNA polymerase III polC-type N-terminus I; Region: DNA_pol3_a_NI; pfam14480
699034004445	DNA polymerase III polC-type N-terminus II; Region: DNA_pol3_a_NII; pfam11490
699034004446	polC_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold nucleic acid binding domain of Bacillus subtilis type C replicative DNA polymerase III alpha subunit (polC). Replication in B. subtilis and Staphylococcus aureus requires two...; Region: polC_OBF; cd04484
699034004447	generic binding surface II; other site
699034004448	generic binding surface I; other site
699034004449	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III at PolC gene; Region: PHP_PolIIIA_POLC; cd07435
699034004450	active site
699034004451	putative PHP Thumb interface [polypeptide binding]; other site
699034004452	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
699034004453	active site
699034004454	catalytic site [active]
699034004455	substrate binding site [chemical binding]; other site
699034004456	Bacterial DNA polymerase III alpha subunit; Region: DNA_pol3_alpha; pfam07733
699034004457	Helix-hairpin-helix motif; Region: HHH_6; pfam14579
699034004458	Sm and related proteins; Region: Sm_like; cl00259
699034004459	Bacillus subtilis YxlS-like, C-terminal domain; Region: YlxS_C; cd01734
699034004460	putative oligomer interface [polypeptide binding]; other site
699034004461	putative RNA binding site [nucleotide binding]; other site
699034004462	transcription elongation factor NusA; Provisional; Region: nusA; PRK12327
699034004463	NusA N-terminal domain; Region: NusA_N; pfam08529
699034004464	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
699034004465	RNA binding site [nucleotide binding]; other site
699034004466	homodimer interface [polypeptide binding]; other site
699034004467	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
699034004468	G-X-X-G motif; other site
699034004469	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
699034004470	G-X-X-G motif; other site
699034004471	Ylxr homologs; group of conserved hypothetical bacterial proteins of unknown function; structure revealed putative RNA binding cleft; proteins are encoded by an operon that includes other proteins involved in transcription and/or translation; Region: YlxR; cd00279
699034004472	putative RNA binding cleft [nucleotide binding]; other site
699034004473	Ribosomal protein L7Ae/L30e/S12e/Gadd45 family; Region: Ribosomal_L7Ae; cl00600
699034004474	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
699034004475	translation initiation factor IF-2; Region: IF-2; TIGR00487
699034004476	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
699034004477	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
699034004478	G1 box; other site
699034004479	putative GEF interaction site [polypeptide binding]; other site
699034004480	GTP/Mg2+ binding site [chemical binding]; other site
699034004481	Switch I region; other site
699034004482	G2 box; other site
699034004483	G3 box; other site
699034004484	Switch II region; other site
699034004485	G4 box; other site
699034004486	G5 box; other site
699034004487	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
699034004488	Translation-initiation factor 2; Region: IF-2; pfam11987
699034004489	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
699034004490	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
699034004491	Exopolyphosphatase-related proteins [General function prediction only]; Region: COG0618
699034004492	DHH family; Region: DHH; pfam01368
699034004493	DHHA1 domain; Region: DHHA1; pfam02272
699034004494	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK00130
699034004495	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
699034004496	RNA binding site [nucleotide binding]; other site
699034004497	active site
699034004498	bifunctional riboflavin kinase/FMN adenylyltransferase; Reviewed; Region: PRK05627
699034004499	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
699034004500	active site
699034004501	Riboflavin kinase; Region: Flavokinase; pfam01687
699034004502	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
699034004503	16S/18S rRNA binding site [nucleotide binding]; other site
699034004504	S13e-L30e interaction site [polypeptide binding]; other site
699034004505	25S rRNA binding site [nucleotide binding]; other site
699034004506	EDD domain protein, DegV family; Region: DegV; TIGR00762
699034004507	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
699034004508	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
699034004509	RNase E interface [polypeptide binding]; other site
699034004510	trimer interface [polypeptide binding]; other site
699034004511	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
699034004512	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
699034004513	RNase E interface [polypeptide binding]; other site
699034004514	trimer interface [polypeptide binding]; other site
699034004515	active site
699034004516	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
699034004517	putative nucleic acid binding region [nucleotide binding]; other site
699034004518	G-X-X-G motif; other site
699034004519	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
699034004520	RNA binding site [nucleotide binding]; other site
699034004521	domain interface; other site
699034004522	Putative catalytic NodB homology domain of uncharacterized protein YlxY from Bacillus subtilis and its bacterial homologs; Region: CE4_BsYlxY_like; cd10950
699034004523	NodB motif; other site
699034004524	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
699034004525	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
699034004526	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
699034004527	sporulation protein, YlmC/YmxH family; Region: spore_YlmC_YmxH; TIGR02888
699034004528	aspartate kinase I; Reviewed; Region: PRK08210
699034004529	AAK_AKi-DapG-BS: Amino Acid Kinase Superfamily (AAK), AKi-DapG; this CD includes the N-terminal catalytic aspartokinase (AK) domain of  the diaminopimelate-sensitive aspartokinase isoenzyme AKI (DapG), a monofunctional class enzyme found in Bacilli; Region: AAK_AKi-DapG-BS; cd04260
699034004530	putative catalytic residues [active]
699034004531	putative nucleotide binding site [chemical binding]; other site
699034004532	putative aspartate binding site [chemical binding]; other site
699034004533	ACT domains are commonly involved in specifically binding an amino acid or other small ligand leading to regulation of the enzyme; Region: ACT; cl09141
699034004534	ACT domains of the diaminopimelate-sensitive aspartokinase (AK) isoenzyme AKI; Region: ACT_AKi-DapG-BS_2; cd04937
699034004535	Caseinolytic protease (ClpP) is an ATP-dependent protease; Region: Clp_protease_like; cl15763
699034004536	active site
699034004537	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
699034004538	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
699034004539	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
699034004540	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
699034004541	tRNA 2-selenouridine synthase; Provisional; Region: PRK11784
699034004542	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cl00125
699034004543	active site residue [active]
699034004544	ribosomal protein S12 methylthiotransferase RimO; Region: TIGR01125
699034004545	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
699034004546	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
699034004547	FeS/SAM binding site; other site
699034004548	TRAM domain; Region: TRAM; cl01282
699034004549	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; cl00453
699034004550	recombinase A; Provisional; Region: recA; PRK09354
699034004551	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
699034004552	hexamer interface [polypeptide binding]; other site
699034004553	Walker A motif; other site
699034004554	ATP binding site [chemical binding]; other site
699034004555	Walker B motif; other site
699034004556	ribonuclease Y; Region: RNase_Y; TIGR03319
699034004557	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
699034004558	Zn2+ binding site [ion binding]; other site
699034004559	Mg2+ binding site [ion binding]; other site
699034004560	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
699034004561	ATP binding site [chemical binding]; other site
699034004562	putative Mg++ binding site [ion binding]; other site
699034004563	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
699034004564	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
699034004565	Catalytic site [active]
699034004566	The S24, S26 LexA/signal peptidase superfamily contains LexA-related and type I signal peptidase families. The S24 LexA protein domains include: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the...; Region: Peptidase_S24_S26; cl10465
699034004567	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
699034004568	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
699034004569	active site
699034004570	Int/Topo IB signature motif; other site
699034004571	DNA binding site [nucleotide binding]
699034004572	Adenylsuccinate lyase (ASL)_subgroup 2; Region: Adenylsuccinate_lyase_2; cd03302
699034004573	Adenylosuccinate lyase [Nucleotide transport and metabolism]; Region: PurB; COG0015
699034004574	tetramer interface [polypeptide binding]; other site
699034004575	active site
699034004576	Transcriptional regulators [Transcription]; Region: MarR; COG1846
699034004577	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
699034004578	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
699034004579	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
699034004580	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
699034004581	active site turn [active]
699034004582	phosphorylation site [posttranslational modification]
699034004583	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
699034004584	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
699034004585	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
699034004586	putative active site [active]
699034004587	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
699034004588	Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases; Region: GH4_GlvA_pagL_like; cd05298
699034004589	NAD binding site [chemical binding]; other site
699034004590	sugar binding site [chemical binding]; other site
699034004591	divalent metal binding site [ion binding]; other site
699034004592	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
699034004593	dimer interface [polypeptide binding]; other site
699034004594	aspartate aminotransferase; Provisional; Region: PRK07568
699034004595	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
699034004596	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034004597	homodimer interface [polypeptide binding]; other site
699034004598	catalytic residue [active]
699034004599	Galactose-1-phosphate uridylyltransferase [Energy production and conversion]; Region: GalT; COG1085
699034004600	HIT family: HIT (Histidine triad) proteins, named for a motif related to the sequence HxHxH/Qxx (x, a hydrophobic amino acid), are a superfamily of nucleotide hydrolases and transferases, which act on the alpha-phosphate of ribonucleotides. On the basis...; Region: HIT_like; cl00228
699034004601	nucleotide binding site/active site [active]
699034004602	HIT family signature motif; other site
699034004603	catalytic residue [active]
699034004604	Human Ape1-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases; Region: Ape1-like_AP-endo; cd09087
699034004605	active site
699034004606	putative catalytic site [active]
699034004607	DNA binding site [nucleotide binding]
699034004608	putative phosphate binding site [ion binding]; other site
699034004609	metal binding site A [ion binding]; metal-binding site
699034004610	AP binding site [nucleotide binding]; other site
699034004611	metal binding site B [ion binding]; metal-binding site
699034004612	DEDDh 3'-5' exonuclease domain of Caenorhabditis elegans ERI-1, human 3' exonuclease, and similar proteins; Region: ERI-1_3'hExo_like; cd06133
699034004613	active site
699034004614	catalytic site [active]
699034004615	substrate binding site [chemical binding]; other site
699034004616	Glutamine synthetase [Amino acid transport and metabolism]; Region: GlnA; COG0174
699034004617	Glutamine synthetase, catalytic domain; Region: Gln-synt_C; pfam00120
699034004618	diacylglycerol glucosyltransferase; Provisional; Region: PRK13609
699034004619	Monogalactosyldiacylglycerol (MGDG) synthase; Region: MGDG_synth; pfam06925
699034004620	Glycosyltransferase family 28 C-terminal domain; Region: Glyco_tran_28_C; cl19139
699034004621	Predicted transcriptional regulators [Transcription]; Region: COG1695
699034004622	Transcriptional regulator PadR-like family; Region: PadR; pfam03551
699034004623	Protein of unknown function (DUF1700); Region: DUF1700; pfam08006
699034004624	Protein of unknown function (DUF3392); Region: DUF3392; pfam11872
699034004625	Domain of unknown function (DUF4097); Region: DUF4097; pfam13349
699034004626	gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Region: galliderm_ABC; TIGR03740
699034004627	ATP-binding cassette domain of the bacitracin-resistance transporter; Region: ABC_BcrA_bacitracin_resist; cd03268
699034004628	Walker A/P-loop; other site
699034004629	ATP binding site [chemical binding]; other site
699034004630	Q-loop/lid; other site
699034004631	ABC transporter signature motif; other site
699034004632	Walker B; other site
699034004633	D-loop; other site
699034004634	H-loop/switch region; other site
699034004635	lantibiotic protection ABC transporter permease subunit, MutE/EpiE family; Region: lanti_perm_MutE; TIGR03732
699034004636	lantibiotic protection ABC transporter permease subunit, MutG family; Region: lanti_perm_MutG; TIGR03733
699034004637	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034004638	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034004639	dimer interface [polypeptide binding]; other site
699034004640	phosphorylation site [posttranslational modification]
699034004641	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034004642	ATP binding site [chemical binding]; other site
699034004643	Mg2+ binding site [ion binding]; other site
699034004644	G-X-G motif; other site
699034004645	Pyridoxal kinase plays a key role in the synthesis of the active coenzyme pyridoxal-5'-phosphate  (PLP), by catalyzing the phosphorylation of the precursor vitamin B6  in the presence of Zn2+ and ATP. Mammals are unable to synthesize PLP de novo and...; Region: pyridoxal_pyridoxamine_kinase; cd01173
699034004646	dimer interface [polypeptide binding]; other site
699034004647	pyridoxal binding site [chemical binding]; other site
699034004648	ATP binding site [chemical binding]; other site
699034004649	Putative amidase domain; Region: Amidase_6; pfam12671
699034004650	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
699034004651	DNA-binding site [nucleotide binding]; DNA binding site
699034004652	RNA-binding motif; other site
699034004653	FOG: CBS domain [General function prediction only]; Region: COG0517
699034004654	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_30; cd04643
699034004655	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
699034004656	Domain of unknown function (DUF955); Region: DUF955; cl01076
699034004657	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
699034004658	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034004659	non-specific DNA binding site [nucleotide binding]; other site
699034004660	salt bridge; other site
699034004661	sequence-specific DNA binding site [nucleotide binding]; other site
699034004662	Protein of unknown function (DUF2281); Region: DUF2281; cl02355
699034004663	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034004664	non-specific DNA binding site [nucleotide binding]; other site
699034004665	salt bridge; other site
699034004666	sequence-specific DNA binding site [nucleotide binding]; other site
699034004667	Phage tail sheath protein; Region: Phage_sheath_1; cl01389
699034004668	Protein of unknown function (DUF2001); Region: DUF2001; pfam09393
699034004669	Phage XkdN-like protein; Region: XkdN; pfam08890
699034004670	Reovirus sigma C capsid protein; Region: Reo_sigmaC; pfam04582
699034004671	Phage-related protein [Function unknown]; Region: COG5412
699034004672	NlpC/P60 family; Region: NLPC_P60; pfam00877
699034004673	Protein of unknown function (DUF2577); Region: DUF2577; pfam10844
699034004674	Protein of unknown function (DUF2634); Region: DUF2634; pfam10934
699034004675	Baseplate J-like protein; Region: Baseplate_J; pfam04865
699034004676	Uncharacterized protein conserved in bacteria (DUF2313); Region: DUF2313; cl01542
699034004677	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
699034004678	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
699034004679	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
699034004680	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
699034004681	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
699034004682	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
699034004683	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
699034004684	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
699034004685	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
699034004686	Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell division and chromosome partitioning / Cytoskeleton]; Region: ATS1; COG5184
699034004687	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
699034004688	Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell division and chromosome partitioning / Cytoskeleton]; Region: ATS1; COG5184
699034004689	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
699034004690	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
699034004691	Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell division and chromosome partitioning / Cytoskeleton]; Region: ATS1; COG5184
699034004692	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1_2; pfam13540
699034004693	Regulator of chromosome condensation (RCC1) repeat; Region: RCC1; pfam00415
699034004694	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034004695	non-specific DNA binding site [nucleotide binding]; other site
699034004696	salt bridge; other site
699034004697	sequence-specific DNA binding site [nucleotide binding]; other site
699034004698	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034004699	non-specific DNA binding site [nucleotide binding]; other site
699034004700	salt bridge; other site
699034004701	sequence-specific DNA binding site [nucleotide binding]; other site
699034004702	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
699034004703	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034004704	non-specific DNA binding site [nucleotide binding]; other site
699034004705	salt bridge; other site
699034004706	sequence-specific DNA binding site [nucleotide binding]; other site
699034004707	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
699034004708	Major Facilitator Superfamily; Region: MFS_1; pfam07690
699034004709	putative substrate translocation pore; other site
699034004710	Polyhydroxyalkanoic acid inclusion protein (PhaP_Bmeg); Region: PhaP_Bmeg; cl09820
699034004711	Protein of Unknown function (DUF1690); Region: DUF1690; pfam07956
699034004712	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
699034004713	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
699034004714	glycerol kinase; Provisional; Region: glpK; PRK00047
699034004715	Escherichia coli glycerol kinase-like proteins; belongs to the FGGY family of carbohydrate kinases; Region: FGGY_EcGK_like; cd07786
699034004716	N- and C-terminal domain interface [polypeptide binding]; other site
699034004717	active site
699034004718	MgATP binding site [chemical binding]; other site
699034004719	catalytic site [active]
699034004720	metal binding site [ion binding]; metal-binding site
699034004721	glycerol binding site [chemical binding]; other site
699034004722	homotetramer interface [polypeptide binding]; other site
699034004723	homodimer interface [polypeptide binding]; other site
699034004724	FBP binding site [chemical binding]; other site
699034004725	protein IIAGlc interface [polypeptide binding]; other site
699034004726	Predicted transcriptional regulators [Transcription]; Region: COG1725
699034004727	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
699034004728	DNA-binding site [nucleotide binding]; DNA binding site
699034004729	TrkA-C domain; Region: TrkA_C; pfam02080
699034004730	LamB/YcsF family of  lactam utilization protein; Region: LamB_YcsF_like; cd10787
699034004731	putative active site [active]
699034004732	Mn2+ and Fe2+ transporters of the NRAMP family [Inorganic ion transport and metabolism]; Region: MntH; COG1914
699034004733	Allophanate hydrolase subunit 1; Region: AHS1; pfam02682
699034004734	Allophanate hydrolase subunit 1 [Amino acid transport and metabolism]; Region: DUR1; COG2049
699034004735	Allophanate hydrolase subunit 2; Region: AHS2; pfam02626
699034004736	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034004737	non-specific DNA binding site [nucleotide binding]; other site
699034004738	salt bridge; other site
699034004739	sequence-specific DNA binding site [nucleotide binding]; other site
699034004740	Cupin domain; Region: Cupin_2; pfam07883
699034004741	L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily [Cell envelope biogenesis, outer membrane / General function prediction only]; Region: COG4948
699034004742	L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of...; Region: L-Ala-DL-Glu_epimerase; cd03319
699034004743	active site
699034004744	Protein of unknown function (DUF819); Region: DUF819; cl02317
699034004745	putative hydrolase, CocE/NonD family; Region: /NonD; TIGR00976
699034004746	X-Pro dipeptidyl-peptidase C-terminal non-catalytic domain; Region: PepX_C; smart00939
699034004747	This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function.  The conserved domain is similar in structure to chorismate mutase but there is no sequence...; Region: YjgF_YER057c_UK114_like_2; cd06150
699034004748	homotrimer interaction site [polypeptide binding]; other site
699034004749	putative active site [active]
699034004750	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
699034004751	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
699034004752	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
699034004753	Oxidoreductase family, C-terminal alpha/beta domain; Region: GFO_IDH_MocA_C; pfam02894
699034004754	Peptidase M55, D-aminopeptidase dipeptide-binding protein family; Region: DAP_dppA_3; cd08770
699034004755	SxDxEG motif; other site
699034004756	putative active site [active]
699034004757	putative metal binding site [ion binding]; other site
699034004758	Escherichia coli YaeB and related proteins; Region: UPF0066; cd09281
699034004759	homodimer interaction site [polypeptide binding]; other site
699034004760	cofactor binding site; other site
699034004761	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
699034004762	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
699034004763	metal binding site [ion binding]; metal-binding site
699034004764	dimer interface [polypeptide binding]; other site
699034004765	LD-Carboxypeptidase, a serine protease, includes microcin C7 self immunity protein; Region: Peptidase_S66; cd07025
699034004766	dimer interface [polypeptide binding]; other site
699034004767	catalytic triad [active]
699034004768	Protein of unknown function (DUF3867); Region: DUF3867; pfam12983
699034004769	Cysteine hydrolases; This family contains amidohydrolases, like CSHase (N-carbamoylsarcosine amidohydrolase), involved in creatine metabolism and nicotinamidase, converting nicotinamide to nicotinic acid and ammonia in the pyridine nucleotide cycle. It...; Region: cysteine_hydrolases; cd00431
699034004770	catalytic triad [active]
699034004771	conserved cis-peptide bond; other site
699034004772	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
699034004773	Glycerophosphodiester phosphodiesterase domain of Thermoanaerobacter tengcongensis and similar proteins; Region: GDPD_TtGDE_like; cd08563
699034004774	active site
699034004775	catalytic site [active]
699034004776	metal binding site [ion binding]; metal-binding site
699034004777	dimer interface [polypeptide binding]; other site
699034004778	The adenylation domain of nonribosomal peptide synthetases (NRPS); Region: A_NRPS; cd05930
699034004779	amino acid adenylation domain; Region: AA-adenyl-dom; TIGR01733
699034004780	acyl-activating enzyme (AAE) consensus motif; other site
699034004781	AMP binding site [chemical binding]; other site
699034004782	OPT oligopeptide transporter protein; Region: OPT; pfam03169
699034004783	Coenzyme PQQ synthesis protein D (PqqD); Region: PqqD; pfam05402
699034004784	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
699034004785	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
699034004786	ABC transporter; Region: ABC_tran_2; pfam12848
699034004787	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
699034004788	Protein of unknown function (DUF1510); Region: DUF1510; pfam07423
699034004789	D-alanyl-D-alanine carboxypeptidase; Region: Peptidase_M15_4; pfam13539
699034004790	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
699034004791	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
699034004792	DNA-binding site [nucleotide binding]; DNA binding site
699034004793	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
699034004794	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034004795	homodimer interface [polypeptide binding]; other site
699034004796	catalytic residue [active]
699034004797	D-alanine--D-alanine ligase; Reviewed; Region: ddl; PRK01372
699034004798	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
699034004799	ATP-grasp domain; Region: ATP-grasp_4; cl17255
699034004800	competence damage-inducible protein A; Provisional; Region: PRK00549
699034004801	Competence-damaged protein. CinA is the first gene in the competence- inducible (cin) operon and is thought to be specifically required at some stage in the process of transformation. This domain is closely related to a domain, found in a variety of...; Region: cinA; cd00885
699034004802	putative MPT binding site; other site
699034004803	Competence-damaged protein; Region: CinA; pfam02464
699034004804	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
699034004805	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
699034004806	active site
699034004807	motif I; other site
699034004808	motif II; other site
699034004809	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
699034004810	Zinc dependent phospholipase C; Region: Zn_dep_PLPC; pfam00882
699034004811	PAS domain; Region: PAS_9; pfam13426
699034004812	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
699034004813	putative active site [active]
699034004814	heme pocket [chemical binding]; other site
699034004815	psp operon transcriptional activator PspF; Region: phageshock_pspF; TIGR02974
699034004816	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034004817	Walker A motif; other site
699034004818	ATP binding site [chemical binding]; other site
699034004819	Walker B motif; other site
699034004820	arginine finger; other site
699034004821	EamA-like transporter family; Region: EamA; pfam00892
699034004822	Carboxylate/Amino Acid/Amine Transporter; Region: 2A78; TIGR00950
699034004823	EamA-like transporter family; Region: EamA; pfam00892
699034004824	Predicted Fe-S oxidoreductase [General function prediction only]; Region: COG1242
699034004825	Elongator protein 3, MiaB family, Radical SAM; Region: Elp3; smart00729
699034004826	Protein of unknown function, DUF606; Region: DUF606; cl01273
699034004827	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_IV; cd01994
699034004828	Ligand Binding Site [chemical binding]; other site
699034004829	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
699034004830	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
699034004831	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
699034004832	Integrase core domain; Region: rve; pfam00665
699034004833	Integrase core domain; Region: rve_2; pfam13333
699034004834	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
699034004835	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
699034004836	PAS fold; Region: PAS_3; pfam08447
699034004837	putative active site [active]
699034004838	heme pocket [chemical binding]; other site
699034004839	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
699034004840	metal binding site [ion binding]; metal-binding site
699034004841	active site
699034004842	I-site; other site
699034004843	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
699034004844	metal binding site [ion binding]; metal-binding site
699034004845	active site
699034004846	I-site; other site
699034004847	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
699034004848	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
699034004849	PAS fold; Region: PAS_3; pfam08447
699034004850	putative active site [active]
699034004851	heme pocket [chemical binding]; other site
699034004852	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
699034004853	Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592
699034004854	DNA binding residues [nucleotide binding]
699034004855	dimer interface [polypeptide binding]; other site
699034004856	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
699034004857	Uncharacterized membrane protein [Function unknown]; Region: SapB; COG1285
699034004858	MgtC family; Region: MgtC; pfam02308
699034004859	Nicotinamidase_ related amidohydrolases.  Cysteine hydrolases of unknown function that share the catalytic triad with other amidohydrolases, like nicotinamidase, which converts nicotinamide to nicotinic acid and ammonia; Region: nicotinamidase_related; cd01014
699034004860	catalytic triad [active]
699034004861	conserved cis-peptide bond; other site
699034004862	Predicted transcriptional regulators [Transcription]; Region: COG1733
699034004863	HxlR-like helix-turn-helix; Region: HxlR; pfam01638
699034004864	Predicted acetyltransferase [General function prediction only]; Region: COG3393
699034004865	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
699034004866	Putative lysophospholipase; Region: Hydrolase_4; cl19140
699034004867	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
699034004868	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
699034004869	Catalytic NodB homology domain of Bacillus subtilis polysaccharide deacetylase PdaA, and its bacterial homologs; Region: CE4_BsPdaA_like; cd10948
699034004870	delta-lactam-biosynthetic de-N-acetylase; Region: spore_pdaA; TIGR02884
699034004871	NodB motif; other site
699034004872	active site
699034004873	catalytic site [active]
699034004874	Cd binding site [ion binding]; other site
699034004875	bifunctional ATP-dependent DNA helicase/DNA polymerase III subunit epsilon; Validated; Region: PRK08074
699034004876	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
699034004877	active site
699034004878	catalytic site [active]
699034004879	substrate binding site [chemical binding]; other site
699034004880	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
699034004881	Helicase C-terminal domain; Region: Helicase_C_2; pfam13307
699034004882	Predicted double-stranded RNA/RNA-DNA hybrid binding protein [General function prediction only]; Region: COG3341
699034004883	Caulimovirus viroplasmin; Region: Cauli_VI; pfam01693
699034004884	Bacterial RNase HI containing a hybrid binding domain (HBD) at the N-terminus; Region: RNase_HI_bacteria_like; cd09277
699034004885	RNA/DNA hybrid binding site [nucleotide binding]; other site
699034004886	active site
699034004887	peroxiredoxin; Provisional; Region: PRK13189
699034004888	Peroxiredoxin (PRX) family, 1-cys PRX subfamily; composed of PRXs containing only one conserved cysteine, which serves as the peroxidatic cysteine. They are homodimeric thiol-specific antioxidant (TSA) proteins that confer a protective role in cells by...; Region: PRX_1cys; cd03016
699034004889	dimer interface [polypeptide binding]; other site
699034004890	decamer (pentamer of dimers) interface [polypeptide binding]; other site
699034004891	catalytic triad [active]
699034004892	Glyco_18 domain; Region: Glyco_18; smart00636
699034004893	The GH18 (glycosyl hydrolases, family 18) type II chitinases hydrolyze chitin, an abundant polymer of N-acetylglucosamine and have been identified in bacteria, fungi, insects, plants, viruses, and protozoan parasites. The structure of this domain is an...; Region: GH18_chitinase; cd06548
699034004894	active site
699034004895	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
699034004896	VanW like protein; Region: VanW; pfam04294
699034004897	G5 domain; Region: G5; pfam07501
699034004898	Largest subunit of RNA polymerase (RNAP), N-terminal domain; Region: RNAP_largest_subunit_N; cl19114
699034004899	hypothetical protein; Provisional; Region: PHA02938
699034004900	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
699034004901	IncA protein; Region: IncA; pfam04156
699034004902	tol-pal system protein YbgF; Region: tol_pal_ybgF; TIGR02795
699034004903	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
699034004904	binding surface
699034004905	TPR motif; other site
699034004906	Putative effector of murein hydrolase LrgA [General function prediction only]; Region: COG1380
699034004907	Putative effector of murein hydrolase [Cell envelope biogenesis, outer membrane]; Region: LrgB; COG1346
699034004908	Uncharacterized conserved protein [Function unknown]; Region: COG1284
699034004909	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
699034004910	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
699034004911	MORN repeat; Region: MORN; cl14787
699034004912	MORN repeat; Region: MORN; cl14787
699034004913	CAP-associated N-terminal; Region: CAP_assoc_N; pfam14504
699034004914	Uncharacterized protein with SCP/PR1 domains [Function unknown]; Region: COG2340
699034004915	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
699034004916	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
699034004917	Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917
699034004918	NodB motif; other site
699034004919	active site
699034004920	catalytic site [active]
699034004921	metal binding site [ion binding]; metal-binding site
699034004922	para-aminobenzoate synthase component II; Provisional; Region: PRK08857
699034004923	Type 1 glutamine amidotransferase (GATase1) domain found in Anthranilate synthase; Region: GATase1_Anthranilate_Synthase; cd01743
699034004924	glutamine binding [chemical binding]; other site
699034004925	catalytic triad [active]
699034004926	Anthranilate synthase component I, N terminal region; Region: Anth_synt_I_N; pfam04715
699034004927	Anthranilate/para-aminobenzoate synthases component I [Amino acid transport and metabolism / Coenzyme metabolism]; Region: TrpE; COG0147
699034004928	chorismate binding enzyme; Region: Chorismate_bind; cl10555
699034004929	Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase [Amino acid transport and metabolism / Coenzyme metabolism]; Region: IlvE; COG0115
699034004930	PyridoxaL 5'-Phosphate Dependent Enzymes class IV (PLPDE_IV). This D-amino acid superfamily, one of five classes of PLPDE, consists of branched-chain amino acid aminotransferases (BCAT), D-amino acid transferases (DAAT), and...; Region: PLPDE_IV; cd00449
699034004931	homodimer interface [polypeptide binding]; other site
699034004932	substrate-cofactor binding pocket; other site
699034004933	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034004934	catalytic residue [active]
699034004935	GTP cyclohydrolase I; Provisional; Region: folE; PRK09347
699034004936	active site
699034004937	Dihydropteroate synthase and related enzymes [Coenzyme metabolism]; Region: FolP; COG0294
699034004938	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
699034004939	substrate binding pocket [chemical binding]; other site
699034004940	dimer interface [polypeptide binding]; other site
699034004941	inhibitor binding site; inhibition site
699034004942	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
699034004943	homooctamer interface [polypeptide binding]; other site
699034004944	active site
699034004945	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
699034004946	catalytic center binding site [active]
699034004947	ATP binding site [chemical binding]; other site
699034004948	DAHP synthetase I family; Region: DAHP_synth_1; cl17225
699034004949	3-deoxy-7-phosphoheptulonate synthase; Reviewed; Region: PRK08673
699034004950	DNA primase; Validated; Region: dnaG; PRK05667
699034004951	CHC2 zinc finger; Region: zf-CHC2; pfam01807
699034004952	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
699034004953	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
699034004954	active site
699034004955	metal binding site [ion binding]; metal-binding site
699034004956	interdomain interaction site; other site
699034004957	DnaB-helicase binding domain of primase; Region: DnaB_bind; pfam10410
699034004958	RNA polymerase sigma factor RpoD; Validated; Region: PRK09210
699034004959	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
699034004960	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
699034004961	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
699034004962	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
699034004963	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
699034004964	DNA binding residues [nucleotide binding]
699034004965	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
699034004966	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
699034004967	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3323
699034004968	Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: FabG; COG1028
699034004969	NADPH-dependent FMN reductase; Region: FMN_red; cl00438
699034004970	Predicted flavin-nucleotide-binding protein [General function prediction only]; Region: COG3467
699034004971	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
699034004972	Zn2+ binding site [ion binding]; other site
699034004973	Mg2+ binding site [ion binding]; other site
699034004974	Protein of unknown function (DUF1648); Region: DUF1648; cl19856
699034004975	Predicted transcriptional regulators [Transcription]; Region: COG1725
699034004976	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
699034004977	DNA-binding site [nucleotide binding]; DNA binding site
699034004978	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034004979	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034004980	active site
699034004981	phosphorylation site [posttranslational modification]
699034004982	intermolecular recognition site; other site
699034004983	dimerization interface [polypeptide binding]; other site
699034004984	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034004985	DNA binding site [nucleotide binding]
699034004986	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034004987	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034004988	dimer interface [polypeptide binding]; other site
699034004989	phosphorylation site [posttranslational modification]
699034004990	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034004991	ATP binding site [chemical binding]; other site
699034004992	Mg2+ binding site [ion binding]; other site
699034004993	G-X-G motif; other site
699034004994	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
699034004995	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
699034004996	Walker A/P-loop; other site
699034004997	ATP binding site [chemical binding]; other site
699034004998	Q-loop/lid; other site
699034004999	ABC transporter signature motif; other site
699034005000	Walker B; other site
699034005001	D-loop; other site
699034005002	H-loop/switch region; other site
699034005003	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
699034005004	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
699034005005	FtsX-like permease family; Region: FtsX; pfam02687
699034005006	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
699034005007	FtsX-like permease family; Region: FtsX; pfam02687
699034005008	CRISPR/Cas system-associated transcriptional regulator CasRa; Region: CasRa_I-A; cd09655
699034005009	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
699034005010	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
699034005011	Beta-lactamase; Region: Beta-lactamase; pfam00144
699034005012	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034005013	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034005014	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034005015	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
699034005016	active site residue [active]
699034005017	potential frameshift: common BLAST hit: gi|260686685|ref|YP_003217818.1| membrane protein ( phage infection protein)
699034005018	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
699034005019	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
699034005020	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034005021	Walker A/P-loop; other site
699034005022	ATP binding site [chemical binding]; other site
699034005023	Q-loop/lid; other site
699034005024	ABC transporter signature motif; other site
699034005025	Walker B; other site
699034005026	D-loop; other site
699034005027	H-loop/switch region; other site
699034005028	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
699034005029	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
699034005030	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
699034005031	Walker A/P-loop; other site
699034005032	ATP binding site [chemical binding]; other site
699034005033	Q-loop/lid; other site
699034005034	ABC transporter signature motif; other site
699034005035	Walker B; other site
699034005036	D-loop; other site
699034005037	H-loop/switch region; other site
699034005038	Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and...; Region: rubredoxin_SM; cd00729
699034005039	Rubredoxin; Region: Rubredoxin; pfam00301
699034005040	iron binding site [ion binding]; other site
699034005041	rubrerythrin-like, diiron-binding domain; Region: Rubrerythrin_like; cd01046
699034005042	Rubrerythrin [Energy production and conversion]; Region: COG1592
699034005043	diiron binding motif [ion binding]; other site
699034005044	CAAX protease self-immunity; Region: Abi; pfam02517
699034005045	Dienelactone hydrolase family; Region: DLH; pfam01738
699034005046	FeoA domain; Region: FeoA; pfam04023
699034005047	Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918
699034005048	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
699034005049	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
699034005050	G1 box; other site
699034005051	GTP/Mg2+ binding site [chemical binding]; other site
699034005052	Switch I region; other site
699034005053	G2 box; other site
699034005054	G3 box; other site
699034005055	Switch II region; other site
699034005056	G4 box; other site
699034005057	G5 box; other site
699034005058	Nucleoside recognition; Region: Gate; pfam07670
699034005059	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
699034005060	Nucleoside recognition; Region: Gate; pfam07670
699034005061	Mitochondrial biogenesis AIM24; Region: AIM24; pfam01987
699034005062	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
699034005063	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034005064	dimer interface [polypeptide binding]; other site
699034005065	conserved gate region; other site
699034005066	putative PBP binding loops; other site
699034005067	ABC-ATPase subunit interface; other site
699034005068	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
699034005069	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
699034005070	Walker A/P-loop; other site
699034005071	ATP binding site [chemical binding]; other site
699034005072	Q-loop/lid; other site
699034005073	ABC transporter signature motif; other site
699034005074	Walker B; other site
699034005075	D-loop; other site
699034005076	H-loop/switch region; other site
699034005077	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
699034005078	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
699034005079	substrate binding pocket [chemical binding]; other site
699034005080	membrane-bound complex binding site; other site
699034005081	hinge residues; other site
699034005082	Protein of unknown function (DUF3793); Region: DUF3793; pfam12672
699034005083	Predicted transcriptional regulator [Transcription]; Region: COG2378
699034005084	HTH domain; Region: HTH_11; pfam08279
699034005085	WYL domain; Region: WYL; pfam13280
699034005086	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
699034005087	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
699034005088	Probable transposase; Region: OrfB_IS605; pfam01385
699034005089	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
699034005090	ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism]; Region: AbcC; COG1135
699034005091	ATP-binding cassette domain of methionine transporter; Region: ABC_MetN_methionine_transporter; cd03258
699034005092	Walker A/P-loop; other site
699034005093	ATP binding site [chemical binding]; other site
699034005094	Q-loop/lid; other site
699034005095	ABC transporter signature motif; other site
699034005096	Walker B; other site
699034005097	D-loop; other site
699034005098	H-loop/switch region; other site
699034005099	NIL domain; Region: NIL; pfam09383
699034005100	ectoine/hydroxyectoine ABC transporter, permease protein EhuD; Region: ectoine_ehuD; TIGR03003
699034005101	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034005102	dimer interface [polypeptide binding]; other site
699034005103	conserved gate region; other site
699034005104	putative PBP binding loops; other site
699034005105	ABC-ATPase subunit interface; other site
699034005106	ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism]; Region: NlpA; COG1464
699034005107	NLPA lipoprotein; Region: Lipoprotein_9; pfam03180
699034005108	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
699034005109	PAS domain; Region: PAS_8; pfam13188
699034005110	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034005111	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034005112	dimer interface [polypeptide binding]; other site
699034005113	phosphorylation site [posttranslational modification]
699034005114	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034005115	ATP binding site [chemical binding]; other site
699034005116	Mg2+ binding site [ion binding]; other site
699034005117	G-X-G motif; other site
699034005118	Alkyladenine DNA glycosylase catalyzes the first step in base excision repair; Region: AAG; cd00540
699034005119	active site
699034005120	DNA binding site [nucleotide binding]
699034005121	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
699034005122	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034005123	non-specific DNA binding site [nucleotide binding]; other site
699034005124	salt bridge; other site
699034005125	sequence-specific DNA binding site [nucleotide binding]; other site
699034005126	Cupin domain; Region: Cupin_2; pfam07883
699034005127	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
699034005128	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; pfam03807
699034005129	Pyrroline-5-carboxylate reductase dimerization; Region: P5CR_dimer; pfam14748
699034005130	Protein of unknown function (DUF1002); Region: DUF1002; pfam06207
699034005131	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
699034005132	RNA polymerase sigma factor RpoD, C-terminal domain; Region: RpoD_Cterm; TIGR02393
699034005133	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
699034005134	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
699034005135	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
699034005136	DNA binding residues [nucleotide binding]
699034005137	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
699034005138	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
699034005139	2-deoxyribose-5-phosphate aldolase (DERA) of the DeoC family; Region: DeoC; cd00959
699034005140	intersubunit interface [polypeptide binding]; other site
699034005141	active site
699034005142	catalytic residue [active]
699034005143	Predicted transcriptional regulators [Transcription]; Region: COG1725
699034005144	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
699034005145	DNA-binding site [nucleotide binding]; DNA binding site
699034005146	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
699034005147	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
699034005148	Walker A/P-loop; other site
699034005149	ATP binding site [chemical binding]; other site
699034005150	Q-loop/lid; other site
699034005151	ABC transporter signature motif; other site
699034005152	Walker B; other site
699034005153	D-loop; other site
699034005154	H-loop/switch region; other site
699034005155	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
699034005156	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
699034005157	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
699034005158	catalytic residues [active]
699034005159	4Fe-4S binding domain; Region: Fer4_5; pfam12801
699034005160	4Fe-4S dicluster domain; Region: Fer4_10; pfam13237
699034005161	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
699034005162	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
699034005163	Domain of unknown function (DUF2935); Region: DUF2935; pfam11155
699034005164	Domain of unknown function (DUF2935); Region: DUF2935; pfam11155
699034005165	Pantoate-beta-alanine ligase; Region: PanC; cd00560
699034005166	active site
699034005167	ATP-binding site [chemical binding]; other site
699034005168	pantoate-binding site; other site
699034005169	HXXH motif; other site
699034005170	Ketopantoate hydroxymethyltransferase (KPHMT) is the first enzyme in the pantothenate biosynthesis pathway. Ketopantoate hydroxymethyltransferase (KPHMT) catalyzes the first committed step in the biosynthesis of pantothenate (vitamin B5), which is a...; Region: KPHMT-like; cd06557
699034005171	oligomerization interface [polypeptide binding]; other site
699034005172	active site
699034005173	metal binding site [ion binding]; metal-binding site
699034005174	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
699034005175	PAS fold; Region: PAS_3; pfam08447
699034005176	putative active site [active]
699034005177	heme pocket [chemical binding]; other site
699034005178	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
699034005179	metal binding site [ion binding]; metal-binding site
699034005180	active site
699034005181	I-site; other site
699034005182	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
699034005183	Helix-Turn-Helix DNA binding domain of the BltR transcription regulator; Region: HTH_BltR; cd04782
699034005184	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
699034005185	DNA binding residues [nucleotide binding]
699034005186	dimer interface [polypeptide binding]; other site
699034005187	Transcriptional regulator, effector-binding domain/component [Transcription / Signal transduction mechanisms]; Region: COG4978
699034005188	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
699034005189	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
699034005190	G1 box; other site
699034005191	GTP/Mg2+ binding site [chemical binding]; other site
699034005192	Switch I region; other site
699034005193	G2 box; other site
699034005194	G3 box; other site
699034005195	Switch II region; other site
699034005196	G4 box; other site
699034005197	G5 box; other site
699034005198	Nucleoside recognition; Region: Gate; pfam07670
699034005199	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
699034005200	Nucleoside recognition; Region: Gate; pfam07670
699034005201	FeoA domain; Region: FeoA; cl00838
699034005202	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
699034005203	Coenzyme A binding pocket [chemical binding]; other site
699034005204	Predicted membrane protein (DUF2232); Region: DUF2232; cl01728
699034005205	tyrosyl-tRNA synthetase; Provisional; Region: PRK13354
699034005206	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
699034005207	active site
699034005208	HIGH motif; other site
699034005209	dimer interface [polypeptide binding]; other site
699034005210	KMSKS motif; other site
699034005211	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
699034005212	RNA binding surface [nucleotide binding]; other site
699034005213	delta-lactam-biosynthetic de-N-acetylase; Region: spore_pdaA; TIGR02884
699034005214	Catalytic NodB homology domain of Streptococcus mutans polysaccharide deacetylase PgdA, Bacillus subtilis YheN, and similar proteins; Region: CE4_SmPgdA_like; cd10944
699034005215	NodB motif; other site
699034005216	active site
699034005217	catalytic site [active]
699034005218	Zn binding site [ion binding]; other site
699034005219	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
699034005220	EamA-like transporter family; Region: EamA; pfam00892
699034005221	EamA-like transporter family; Region: EamA; pfam00892
699034005222	Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and...; Region: rubredoxin_SM; cd00729
699034005223	Rubredoxin; Region: Rubredoxin; pfam00301
699034005224	iron binding site [ion binding]; other site
699034005225	rubrerythrin-like, diiron-binding domain; Region: Rubrerythrin_like; cd01046
699034005226	Rubrerythrin [Energy production and conversion]; Region: COG1592
699034005227	diiron binding motif [ion binding]; other site
699034005228	Domain of unknown function (DUF362); Region: DUF362; cl19822
699034005229	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
699034005230	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
699034005231	dihydroorotase; Validated; Region: pyrC; PRK09357
699034005232	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
699034005233	Dihydroorotase (DHOase), subgroup IIa; DHOases catalyze the reversible interconversion of carbamoyl aspartate to dihydroorotate, a key reaction in pyrimidine biosynthesis. This subgroup also contains proteins that lack the active site, like unc-33, a C; Region: DHOase_IIa; cd01317
699034005234	active site
699034005235	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
699034005236	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
699034005237	FtsX-like permease family; Region: FtsX; pfam02687
699034005238	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
699034005239	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
699034005240	Walker A/P-loop; other site
699034005241	ATP binding site [chemical binding]; other site
699034005242	Q-loop/lid; other site
699034005243	ABC transporter signature motif; other site
699034005244	Walker B; other site
699034005245	D-loop; other site
699034005246	H-loop/switch region; other site
699034005247	Membrane-fusion protein [Cell envelope biogenesis, outer membrane]; Region: AcrA; COG0845
699034005248	Biotin-lipoyl like; Region: Biotin_lipoyl_2; cl19169
699034005249	HlyD family secretion protein; Region: HlyD_3; pfam13437
699034005250	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034005251	His Kinase A (phosphoacceptor) domain; Region: HisKA; smart00388
699034005252	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034005253	ATP binding site [chemical binding]; other site
699034005254	Mg2+ binding site [ion binding]; other site
699034005255	G-X-G motif; other site
699034005256	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034005257	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034005258	active site
699034005259	phosphorylation site [posttranslational modification]
699034005260	intermolecular recognition site; other site
699034005261	dimerization interface [polypeptide binding]; other site
699034005262	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034005263	DNA binding site [nucleotide binding]
699034005264	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
699034005265	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
699034005266	Walker A/P-loop; other site
699034005267	ATP binding site [chemical binding]; other site
699034005268	Q-loop/lid; other site
699034005269	ABC transporter signature motif; other site
699034005270	Walker B; other site
699034005271	D-loop; other site
699034005272	H-loop/switch region; other site
699034005273	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
699034005274	FtsX-like permease family; Region: FtsX; pfam02687
699034005275	Gamma-glutamyltransferase [Amino acid transport and metabolism]; Region: Ggt; COG0405
699034005276	Rhodanese-related sulfurtransferase [Inorganic ion transport and metabolism]; Region: SseA; COG2897
699034005277	Thiosulfate sulfurtransferase (TST), N-terminal, inactive domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the 1st repeat, which does not contain the catalytically active Cys residue. The role of the 1st repeat is uncertain, but it...; Region: TST_Repeat_1; cd01448
699034005278	active site residue [active]
699034005279	Thiosulfate sulfurtransferase (TST), C-terminal, catalytic domain. TST contains 2 copies of the Rhodanese Homology Domain; this is the second repeat. Only the second repeat contains the catalytically active Cys residue; Region: TST_Repeat_2; cd01449
699034005280	active site residue [active]
699034005281	ferredoxin-NADP(+) reductase subunit alpha; Reviewed; Region: PRK06222
699034005282	FAD/NAD binding domain in the electron transfer subunit of dihydroorotate dehydrogenase-like proteins. Dihydroorotate dehydrogenases (DHODs) catalyze the only redox reaction in pyrimidine de novo biosynthesis. They catalyze the oxidation of (S)...; Region: DHOD_e_trans_like1; cd06219
699034005283	FAD binding pocket [chemical binding]; other site
699034005284	FAD binding motif [chemical binding]; other site
699034005285	phosphate binding motif [ion binding]; other site
699034005286	beta-alpha-beta structure motif; other site
699034005287	NAD binding pocket [chemical binding]; other site
699034005288	Iron coordination center [ion binding]; other site
699034005289	putative oxidoreductase; Provisional; Region: PRK12831
699034005290	Dihydroprymidine dehydrogenase domain II, 4Fe-4S cluster; Region: Fer4_20; pfam14691
699034005291	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
699034005292	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
699034005293	Cache domain; Region: Cache_1; pfam02743
699034005294	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
699034005295	metal binding site [ion binding]; metal-binding site
699034005296	active site
699034005297	I-site; other site
699034005298	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
699034005299	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
699034005300	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
699034005301	Walker A/P-loop; other site
699034005302	ATP binding site [chemical binding]; other site
699034005303	Q-loop/lid; other site
699034005304	ABC transporter signature motif; other site
699034005305	Walker B; other site
699034005306	D-loop; other site
699034005307	H-loop/switch region; other site
699034005308	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
699034005309	FtsX-like permease family; Region: FtsX; pfam02687
699034005310	multidrug efflux pump VmrA; Reviewed; Region: vmrA; PRK09575
699034005311	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
699034005312	Fic family protein [Function unknown]; Region: COG3177
699034005313	Fic/DOC family; Region: Fic; pfam02661
699034005314	NADPH-dependent FMN reductase; Region: FMN_red; cl00438
699034005315	Domain of unknown function (DUF1836); Region: DUF1836; pfam08876
699034005316	Haemolysin-III related; Region: HlyIII; cl03831
699034005317	channel protein, hemolysin III family; Region: hlyIII; TIGR01065
699034005318	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
699034005319	Histidyl-tRNA synthetase; Region: tRNA-synt_His; pfam13393
699034005320	motif 1; other site
699034005321	dimer interface [polypeptide binding]; other site
699034005322	active site
699034005323	motif 2; other site
699034005324	motif 3; other site
699034005325	ATP phosphoribosyltransferase catalytic subunit; Reviewed; Region: hisG; PRK01686
699034005326	ATP phosphoribosyltransferase [Amino acid transport and metabolism]; Region: HisG; COG0040
699034005327	Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism]; Region: HisC; COG0079
699034005328	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
699034005329	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034005330	homodimer interface [polypeptide binding]; other site
699034005331	catalytic residue [active]
699034005332	Imidazoleglycerol-phosphate dehydratase; Region: IGPD; cd07914
699034005333	putative active site pocket [active]
699034005334	4-fold oligomerization interface [polypeptide binding]; other site
699034005335	metal binding residues [ion binding]; metal-binding site
699034005336	3-fold/trimer interface [polypeptide binding]; other site
699034005337	imidazole glycerol phosphate synthase subunit HisH; Provisional; Region: hisH; PRK13142
699034005338	Type 1 glutamine amidotransferase (GATase1) domain found in imidazole glycerol phosphate synthase (IGPS); Region: GATase1_IGP_Synthase; cd01748
699034005339	putative active site [active]
699034005340	oxyanion strand; other site
699034005341	catalytic triad [active]
699034005342	HisA.  Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1...; Region: HisA; cd04732
699034005343	catalytic residues [active]
699034005344	The cyclase subunit of imidazoleglycerol phosphate synthase (HisF). Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)...; Region: HisF; cd04731
699034005345	substrate binding site [chemical binding]; other site
699034005346	glutamase interaction surface [polypeptide binding]; other site
699034005347	bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein; Reviewed; Region: PRK02759
699034005348	phosphoribosyl-AMP cyclohydrolase; Reviewed; Region: hisI; PRK00051
699034005349	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) MazG-like domain found in Escherichia coli phosphoribosyl-ATP pyrophosphohydrolase (HisIE or PRATP-PH) and its homologs; Region: NTP-PPase_HisIE_like; cd11534
699034005350	metal binding site [ion binding]; metal-binding site
699034005351	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
699034005352	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
699034005353	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
699034005354	Catalytic NodB homology domain of Streptococcus mutans polysaccharide deacetylase PgdA, Bacillus subtilis YheN, and similar proteins; Region: CE4_SmPgdA_like; cd10944
699034005355	NodB motif; other site
699034005356	active site
699034005357	catalytic site [active]
699034005358	Zn binding site [ion binding]; other site
699034005359	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
699034005360	SurA N-terminal domain; Region: SurA_N_3; cl07813
699034005361	PPIC-type PPIASE domain; Region: Rotamase_3; pfam13616
699034005362	RNA polymerase sigma-70 factor, TIGR02954 family; Region: Sig70_famx3
699034005363	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
699034005364	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
699034005365	DNA binding residues [nucleotide binding]
699034005366	Domain of unknown function (DUF4163); Region: DUF4163; pfam13739
699034005367	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
699034005368	Domain of unknown function (DUF4163); Region: DUF4163; pfam13739
699034005369	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
699034005370	Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family [Posttranslational modification, protein turnover, chaperones]; Region: XdhC; COG1975
699034005371	XdhC and CoxI family; Region: XdhC_CoxI; pfam02625
699034005372	XdhC Rossmann domain; Region: XdhC_C; pfam13478
699034005373	Protein of unknown function DUF45; Region: DUF45; pfam01863
699034005374	ACT domain; Region: ACT_5; pfam13710
699034005375	ketol-acid reductoisomerase; Provisional; Region: PRK05479
699034005376	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvN; pfam07991
699034005377	Acetohydroxy acid isomeroreductase, catalytic domain; Region: IlvC; pfam01450
699034005378	acetolactate synthase, large subunit, biosynthetic type; Region: acolac_lg; TIGR00118
699034005379	Pyrimidine (PYR) binding domain of POX and related proteins; Region: TPP_PYR_POX_like; cd07035
699034005380	PYR/PP interface [polypeptide binding]; other site
699034005381	dimer interface [polypeptide binding]; other site
699034005382	TPP binding site [chemical binding]; other site
699034005383	Thiamine pyrophosphate enzyme, central domain; Region: TPP_enzyme_M; pfam00205
699034005384	Thiamine pyrophosphate (TPP) family, Acetohydroxyacid synthase (AHAS) subfamily, TPP-binding module; composed of proteins similar to the large catalytic subunit of AHAS. AHAS catalyzes the condensation of two molecules of pyruvate to give the...; Region: TPP_AHAS; cd02015
699034005385	TPP-binding site [chemical binding]; other site
699034005386	dimer interface [polypeptide binding]; other site
699034005387	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
699034005388	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
699034005389	Int/Topo IB signature motif; other site
699034005390	The HIRAN protein (HIP116, Rad5p N-terminal) is found in the N-terminal regions of the SWI2/SNF2 proteins typified by HIP116 and Rad5p; Region: HIRAN; smart00910
699034005391	C-terminal putative kinase domain of FAM20 (family with sequence similarity 20), Drosophila Four-jointed (Fj), and related proteins; Region: FAM20_C_like; cl05973
699034005392	HipA-like C-terminal domain; Region: HipA_C; pfam07804
699034005393	putative catalytic residues [active]
699034005394	putative catalytic loop [active]
699034005395	Domain of unknown function (DUF955); Region: DUF955; pfam06114
699034005396	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034005397	non-specific DNA binding site [nucleotide binding]; other site
699034005398	salt bridge; other site
699034005399	sequence-specific DNA binding site [nucleotide binding]; other site
699034005400	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
699034005401	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034005402	non-specific DNA binding site [nucleotide binding]; other site
699034005403	salt bridge; other site
699034005404	sequence-specific DNA binding site [nucleotide binding]; other site
699034005405	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034005406	non-specific DNA binding site [nucleotide binding]; other site
699034005407	salt bridge; other site
699034005408	sequence-specific DNA binding site [nucleotide binding]; other site
699034005409	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034005410	non-specific DNA binding site [nucleotide binding]; other site
699034005411	salt bridge; other site
699034005412	sequence-specific DNA binding site [nucleotide binding]; other site
699034005413	Prophage antirepressor [Transcription]; Region: COG3617
699034005414	BRO family, N-terminal domain; Region: Bro-N; smart01040
699034005415	Phage antirepressor protein KilAC domain; Region: ANT; pfam03374
699034005416	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
699034005417	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034005418	non-specific DNA binding site [nucleotide binding]; other site
699034005419	salt bridge; other site
699034005420	sequence-specific DNA binding site [nucleotide binding]; other site
699034005421	Helix-turn-helix domain; Region: HTH_17; pfam12728
699034005422	Protein of unknown function (DUF2800); Region: DUF2800; pfam10926
699034005423	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
699034005424	Protein of unknown function (DUF2815); Region: DUF2815; pfam10991
699034005425	DNA polymerase I - 3'-5' exonuclease and polymerase domains [DNA replication, recombination, and repair]; Region: PolA; COG0749
699034005426	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_A; cd08642
699034005427	active site
699034005428	DNA binding site [nucleotide binding]
699034005429	catalytic site [active]
699034005430	Virulence-associated protein E; Region: VirE; pfam05272
699034005431	VRR-NUC domain; Region: VRR_NUC; pfam08774
699034005432	Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair]; Region: HepA; COG0553
699034005433	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
699034005434	ATP binding site [chemical binding]; other site
699034005435	putative Mg++ binding site [ion binding]; other site
699034005436	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
699034005437	nucleotide binding region [chemical binding]; other site
699034005438	ATP-binding site [chemical binding]; other site
699034005439	DNA binding residues [nucleotide binding]
699034005440	Sigma-70, region 4; Region: Sigma70_r4_2; pfam08281
699034005441	BRO family, N-terminal domain; Region: Bro-N; smart01040
699034005442	Uncharacterized conserved protein [Function unknown]; Region: COG5484
699034005443	Helix-turn-helix domain; Region: HTH_28; pfam13518
699034005444	Phage terminase large subunit; Region: Terminase_3; cl12054
699034005445	Terminase-like family; Region: Terminase_6; pfam03237
699034005446	Phage portal protein, SPP1 Gp6-like; Region: Phage_prot_Gp6; pfam05133
699034005447	phage portal protein, SPP1 family; Region: portal_SPP1; TIGR01538
699034005448	Phage Mu protein F like protein; Region: Phage_Mu_F; cl10072
699034005449	Phage minor structural protein GP20; Region: Phage_GP20; pfam06810
699034005450	Bacteriophage HK97-gp10, putative tail-component; Region: HK97-gp10_like; pfam04883
699034005451	Phage tail sheath protein; Region: Phage_sheath_1; pfam04984
699034005452	Protein of unknown function (DUF2001); Region: DUF2001; pfam09393
699034005453	Phage XkdN-like protein; Region: XkdN; pfam08890
699034005454	BRO family, N-terminal domain; Region: Bro-N; cl10591
699034005455	Domain of unknown function (DUF4352); Region: DUF4352; pfam11611
699034005456	Short C-terminal domain; Region: SHOCT; pfam09851
699034005457	Methyl-accepting chemotaxis protein (MCP), signaling domain; Region: MCP_signal; cl19050
699034005458	Phage-related minor tail protein [Function unknown]; Region: COG5281
699034005459	tape measure domain; Region: tape_meas_nterm; TIGR02675
699034005460	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
699034005461	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
699034005462	NlpC/P60 family; Region: NLPC_P60; pfam00877
699034005463	Protein of unknown function (DUF2577); Region: DUF2577; pfam10844
699034005464	Protein of unknown function (DUF2634); Region: DUF2634; pfam10934
699034005465	Uncharacterized homolog of phage Mu protein gp47 [Function unknown]; Region: XkdT; COG3299
699034005466	Uncharacterized protein conserved in bacteria (DUF2313); Region: DUF2313; pfam10076
699034005467	Phage tail-collar fibre protein; Region: DUF3751; pfam12571
699034005468	TcdA/TcdB pore forming domain; Region: TcdA_TcdB_pore; pfam12920
699034005469	Viral coat protein; Region: Flexi_CP; pfam00286
699034005470	Abi-like protein; Region: Abi_2; pfam07751
699034005471	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
699034005472	active site
699034005473	metal binding site [ion binding]; metal-binding site
699034005474	Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond...; Region: LRR_RI; cd00116
699034005475	Leucine-rich repeats; other site
699034005476	Substrate binding site [chemical binding]; other site
699034005477	Leucine rich repeat; Region: LRR_8; pfam13855
699034005478	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034005479	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034005480	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034005481	Manganese catalase, ferritin-like diiron-binding domain; Region: Mn_catalase; cd01051
699034005482	Uncharacterized conserved protein [Function unknown]; Region: COG1633
699034005483	dimanganese center [ion binding]; other site
699034005484	Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]; Region: COG1331
699034005485	TRX domain, SSP411 protein family; members of this family are highly conserved proteins present in eukaryotes, bacteria and archaea, about 600-800 amino acids in length, which contain a TRX domain with a redox active CXXC motif. The human/rat protein; Region: SSP411; cd02955
699034005486	catalytic residues [active]
699034005487	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
699034005488	MarR family; Region: MarR_2; pfam12802
699034005489	MarR family; Region: MarR_2; cl17246
699034005490	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
699034005491	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
699034005492	Transposase IS200 like; Region: Y1_Tnp; cl00848
699034005493	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
699034005494	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
699034005495	Probable transposase; Region: OrfB_IS605; pfam01385
699034005496	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
699034005497	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
699034005498	Lysophospholipase [Lipid metabolism]; Region: PldB; COG2267
699034005499	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
699034005500	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034005501	non-specific DNA binding site [nucleotide binding]; other site
699034005502	salt bridge; other site
699034005503	sequence-specific DNA binding site [nucleotide binding]; other site
699034005504	Tetratricopeptide repeat; Region: TPR_12; pfam13424
699034005505	Acetyltransferase (GNAT) domain; Region: Acetyltransf_7; pfam13508
699034005506	Domain of unknown function (DUF348); Region: DUF348; pfam03990
699034005507	G5 domain; Region: G5; pfam07501
699034005508	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3584
699034005509	Members of the SGNH-hydrolase superfamily, a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely...; Region: SGNH_hydrolase_like_4; cd04501
699034005510	active site
699034005511	catalytic triad [active]
699034005512	oxyanion hole [active]
699034005513	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
699034005514	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
699034005515	active site
699034005516	substrate binding site [chemical binding]; other site
699034005517	metal binding site [ion binding]; metal-binding site
699034005518	Virulence factor BrkB; Region: Virul_fac_BrkB; pfam03631
699034005519	PAS fold; Region: PAS_4; pfam08448
699034005520	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034005521	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034005522	dimer interface [polypeptide binding]; other site
699034005523	phosphorylation site [posttranslational modification]
699034005524	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034005525	ATP binding site [chemical binding]; other site
699034005526	Mg2+ binding site [ion binding]; other site
699034005527	G-X-G motif; other site
699034005528	Homoserine dehydrogenase [Amino acid transport and metabolism]; Region: ThrA; COG0460
699034005529	Homoserine dehydrogenase, NAD binding domain; Region: NAD_binding_3; pfam03447
699034005530	Homoserine dehydrogenase; Region: Homoserine_dh; pfam00742
699034005531	Histidinol dehydrogenase, HisD, E.C 1.1.1.23. Histidinol dehydrogenase catalyzes the last two steps in the L-histidine biosynthesis pathway, which is conserved in bacteria, archaea, fungi, and plants. These last two steps are (i) the NAD-dependent...; Region: Histidinol_dh; cd06572
699034005532	histidinol dehydrogenase; Region: hisD; TIGR00069
699034005533	NAD binding site [chemical binding]; other site
699034005534	dimerization interface [polypeptide binding]; other site
699034005535	product binding site; other site
699034005536	substrate binding site [chemical binding]; other site
699034005537	zinc binding site [ion binding]; other site
699034005538	catalytic residues [active]
699034005539	Putative lysophospholipase; Region: Hydrolase_4; cl19140
699034005540	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
699034005541	Mor transcription activator family; Region: Mor; cl02360
699034005542	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
699034005543	nucleotide binding site [chemical binding]; other site
699034005544	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
699034005545	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
699034005546	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
699034005547	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
699034005548	nucleotide binding site [chemical binding]; other site
699034005549	ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; Region: MglA; COG1129
699034005550	First domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_I; cd03216
699034005551	Walker A/P-loop; other site
699034005552	ATP binding site [chemical binding]; other site
699034005553	Q-loop/lid; other site
699034005554	ABC transporter signature motif; other site
699034005555	Walker B; other site
699034005556	D-loop; other site
699034005557	H-loop/switch region; other site
699034005558	Second domain of the ATP-binding cassette component of monosaccharide transport system; Region: ABC_Carb_Monos_II; cd03215
699034005559	Transmembrane subunit (TM) of Escherichia coli AraH and related proteins. E. coli AraH is the TM of a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of the monosaccharide arabinose. This group...; Region: TM_PBP1_transp_AraH_like; cd06579
699034005560	TM-ABC transporter signature motif; other site
699034005561	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: RbsB; COG1879
699034005562	Periplasmic sugar-binding domain of active transport systems that are members of the type I periplasmic binding protein (PBP1) superfamily; Region: PBP1_ABC_sugar_binding_like; cd01536
699034005563	ligand binding site [chemical binding]; other site
699034005564	Uncharacterized conserved protein [Function unknown]; Region: COG1284
699034005565	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
699034005566	potassium-transporting ATPase subunit A; Provisional; Region: PRK05482
699034005567	potassium-transporting ATPase subunit B; Provisional; Region: PRK01122
699034005568	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
699034005569	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
699034005570	K+-transporting ATPase, c chain; Region: KdpC; cl00944
699034005571	cysteine synthase; Region: PLN02565
699034005572	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
699034005573	dimer interface [polypeptide binding]; other site
699034005574	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034005575	catalytic residue [active]
699034005576	Serine acetyltransferase [Amino acid transport and metabolism]; Region: CysE; COG1045
699034005577	Serine acetyltransferase (SAT): SAT catalyzes the CoA-dependent acetylation of the side chain hydroxyl group of L-serine to form O-acetylserine, as the first step of a two-step biosynthetic pathway in bacteria and plants leading to the formation of...; Region: LbH_SAT; cd03354
699034005578	trimer interface [polypeptide binding]; other site
699034005579	active site
699034005580	substrate binding site [chemical binding]; other site
699034005581	CoA binding site [chemical binding]; other site
699034005582	4Fe-4S single cluster domain; Region: Fer4_15; pfam13459
699034005583	methionine aminopeptidase; Provisional; Region: PRK12318
699034005584	SEC-C motif; Region: SEC-C; pfam02810
699034005585	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
699034005586	active site
699034005587	The GIY-YIG domain of uncharacterized protein family UPF0213 related to structure-specific endonuclease SLX1; Region: GIY-YIG_UPF0213; cd10456
699034005588	GIY-YIG motif/motif A; other site
699034005589	putative active site [active]
699034005590	putative metal binding site [ion binding]; other site
699034005591	4-amino-5-hydroxymethyl-2-methyl-pyrimidine phosphate kinase (HMPP-kinase) catalyzes two consecutive phosphorylation steps in the thiamine phosphate biosynthesis pathway, leading to the synthesis of vitamin B1. The first step is the phosphorylation of...; Region: HMPP_kinase; cd01169
699034005592	dimer interface [polypeptide binding]; other site
699034005593	substrate binding site [chemical binding]; other site
699034005594	ATP binding site [chemical binding]; other site
699034005595	4-methyl-5-beta-hydroxyethylthiazole (Thz) kinase catalyzes the phosphorylation of the hydroxylgroup of Thz. A reaction that allows cells to recycle Thz into the thiamine biosynthesis pathway, as an alternative to its synthesis from cysteine, tyrosine...; Region: THZ_kinase; cd01170
699034005596	substrate binding site [chemical binding]; other site
699034005597	multimerization interface [polypeptide binding]; other site
699034005598	ATP binding site [chemical binding]; other site
699034005599	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
699034005600	thiamine phosphate binding site [chemical binding]; other site
699034005601	active site
699034005602	pyrophosphate binding site [ion binding]; other site
699034005603	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
699034005604	active site
699034005605	P-loop; other site
699034005606	phosphorylation site [posttranslational modification]
699034005607	ABC-2 type transporter; Region: ABC2_membrane; cl17235
699034005608	ABC-type multidrug transport system, permease component [Defense mechanisms]; Region: COG0842
699034005609	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
699034005610	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034005611	Walker A/P-loop; other site
699034005612	ATP binding site [chemical binding]; other site
699034005613	Q-loop/lid; other site
699034005614	ABC transporter signature motif; other site
699034005615	Walker B; other site
699034005616	D-loop; other site
699034005617	H-loop/switch region; other site
699034005618	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
699034005619	Predicted transcriptional regulators [Transcription]; Region: COG1725
699034005620	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
699034005621	DNA-binding site [nucleotide binding]; DNA binding site
699034005622	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
699034005623	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
699034005624	Walker A/P-loop; other site
699034005625	ATP binding site [chemical binding]; other site
699034005626	Q-loop/lid; other site
699034005627	ABC transporter signature motif; other site
699034005628	Walker B; other site
699034005629	D-loop; other site
699034005630	H-loop/switch region; other site
699034005631	Imidazolonepropionase and related amidohydrolases [Secondary metabolites biosynthesis, transport, and catabolism]; Region: HutI; COG1228
699034005632	Amidohydrolase; Region: Amidohydro_5; pfam13594
699034005633	Metallo-dependent hydrolases, subgroup A is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the...; Region: Met_dep_hydrolase_A; cd01299
699034005634	active site
699034005635	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
699034005636	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034005637	Walker A/P-loop; other site
699034005638	ATP binding site [chemical binding]; other site
699034005639	Q-loop/lid; other site
699034005640	ABC transporter signature motif; other site
699034005641	Walker B; other site
699034005642	D-loop; other site
699034005643	H-loop/switch region; other site
699034005644	ABC-type Na+ efflux pump, permease component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatB; COG1668
699034005645	Acyltransferase family; Region: Acyl_transf_3; cl19154
699034005646	CAAX protease self-immunity; Region: Abi; pfam02517
699034005647	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
699034005648	metal binding site [ion binding]; metal-binding site
699034005649	active site
699034005650	I-site; other site
699034005651	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
699034005652	Predicted transcriptional regulators [Transcription]; Region: COG1725
699034005653	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
699034005654	DNA-binding site [nucleotide binding]; DNA binding site
699034005655	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
699034005656	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
699034005657	Walker A/P-loop; other site
699034005658	ATP binding site [chemical binding]; other site
699034005659	Q-loop/lid; other site
699034005660	ABC transporter signature motif; other site
699034005661	Walker B; other site
699034005662	D-loop; other site
699034005663	H-loop/switch region; other site
699034005664	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
699034005665	Major Facilitator Superfamily; Region: MFS_1; pfam07690
699034005666	putative substrate translocation pore; other site
699034005667	Mechanosensitive ion channel; Region: MS_channel; pfam00924
699034005668	Predicted membrane protein [Function unknown]; Region: COG3212
699034005669	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
699034005670	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
699034005671	Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426
699034005672	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
699034005673	NADPH-dependent FMN reductase; Region: FMN_red; cl00438
699034005674	Rubredoxin_like; nonheme iron binding domain containing a [Fe(SCys)4] center. The family includes rubredoxins, a small electron transfer protein, and a slightly smaller modular rubredoxin domain present in rubrerythrin and nigerythrin and detected either...; Region: rubredoxin_like; cl00202
699034005675	iron binding site [ion binding]; other site
699034005676	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox_2; pfam07992
699034005677	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
699034005678	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034005679	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034005680	active site
699034005681	phosphorylation site [posttranslational modification]
699034005682	intermolecular recognition site; other site
699034005683	dimerization interface [polypeptide binding]; other site
699034005684	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034005685	DNA binding site [nucleotide binding]
699034005686	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034005687	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034005688	dimer interface [polypeptide binding]; other site
699034005689	phosphorylation site [posttranslational modification]
699034005690	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034005691	ATP binding site [chemical binding]; other site
699034005692	Mg2+ binding site [ion binding]; other site
699034005693	G-X-G motif; other site
699034005694	D-alanyl-alanine synthetase A; Reviewed; Region: ddl; PRK01966
699034005695	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
699034005696	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
699034005697	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
699034005698	Acyltransferase family; Region: Acyl_transf_3; pfam01757
699034005699	Predicted O-acyltransferase [General function prediction only]; Region: COG3274
699034005700	alanine racemase; Reviewed; Region: alr; PRK00053
699034005701	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, VanT and similar proteins; Region: PLPDE_III_VanT; cd06825
699034005702	active site
699034005703	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
699034005704	dimer interface [polypeptide binding]; other site
699034005705	substrate binding site [chemical binding]; other site
699034005706	catalytic residues [active]
699034005707	Uncharacterized conserved protein [Function unknown]; Region: COG0398
699034005708	Predicted membrane-bound metal-dependent hydrolase (DUF457); Region: DUF457; cl00868
699034005709	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
699034005710	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
699034005711	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
699034005712	asparagine synthase (glutamine-hydrolyzing); Region: asn_synth_AEB; TIGR01536
699034005713	Glutamine amidotransferases class-II (GATase) asparagine synthase_B type.  Asparagine synthetase B catalyses the ATP-dependent conversion of aspartate to asparagine. This enzyme is a homodimer, with each monomer composed of a  glutaminase domain and a...; Region: AsnB; cd00712
699034005714	active site
699034005715	The C-terminal domain of Asparagine Synthase B. This domain is always found associated n-terminal amidotransferase domain. Family members that contain this domain catalyse the conversion of aspartate to asparagine. Asparagine synthetase B  catalyzes the...; Region: Asn_Synthase_B_C; cd01991
699034005716	Ligand Binding Site [chemical binding]; other site
699034005717	Molecular Tunnel; other site
699034005718	Domain of unknown function (DUF4356); Region: DUF4356; pfam14266
699034005719	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones]; Region: DegQ; COG0265
699034005720	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
699034005721	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
699034005722	putative metal binding site [ion binding]; other site
699034005723	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
699034005724	putative metal binding site [ion binding]; other site
699034005725	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
699034005726	putative metal binding site [ion binding]; other site
699034005727	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
699034005728	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
699034005729	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
699034005730	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
699034005731	Soluble P-type ATPase [General function prediction only]; Region: COG4087
699034005732	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
699034005733	Domain of unknown function (DUF4356); Region: DUF4356; pfam14266
699034005734	Toxic anion resistance protein (TelA); Region: TelA; pfam05816
699034005735	C-C_Bond_Lyase of the TIM-Barrel fold; Region: C-C_Bond_Lyase; pfam15617
699034005736	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
699034005737	active site
699034005738	TRSP domain C terminus to PRTase_2; Region: TRSP; pfam12500
699034005739	Phosphoribosyl transferase (PRTase); Region: PRTase_1; pfam11202
699034005740	PELOTA RNA binding domain; Region: PELOTA_1; pfam15608
699034005741	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
699034005742	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
699034005743	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
699034005744	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034005745	non-specific DNA binding site [nucleotide binding]; other site
699034005746	salt bridge; other site
699034005747	sequence-specific DNA binding site [nucleotide binding]; other site
699034005748	Cupin domain; Region: Cupin_2; pfam07883
699034005749	Predicted integral membrane protein [Function unknown]; Region: COG5505
699034005750	Zn-dependent dipeptidase, microsomal dipeptidase homolog [Amino acid transport and metabolism]; Region: COG2355
699034005751	renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics; Region: rDP_like; cd01301
699034005752	active site
699034005753	dimer interface [polypeptide binding]; other site
699034005754	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
699034005755	ABC-ATPase subunit  interface; other site
699034005756	dimer interface [polypeptide binding]; other site
699034005757	putative PBP binding regions; other site
699034005758	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
699034005759	ABC-ATPase subunit  interface; other site
699034005760	dimer interface [polypeptide binding]; other site
699034005761	putative PBP binding regions; other site
699034005762	ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism]; Region: CeuD; COG4604
699034005763	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
699034005764	Walker A/P-loop; other site
699034005765	ATP binding site [chemical binding]; other site
699034005766	Q-loop/lid; other site
699034005767	ABC transporter signature motif; other site
699034005768	Walker B; other site
699034005769	D-loop; other site
699034005770	H-loop/switch region; other site
699034005771	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
699034005772	Siderophore binding protein FatB.  These proteins have been shown to function as ABC-type initial receptors in the siderophore-mediated iron uptake in some eubacterial species.  They belong to the TroA superfamily of periplasmic metal binding proteins...; Region: FatB; cd01140
699034005773	putative ligand binding residues [chemical binding]; other site
699034005774	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
699034005775	nucleotidyl binding site; other site
699034005776	metal binding site [ion binding]; metal-binding site
699034005777	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
699034005778	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
699034005779	putative metal binding site [ion binding]; other site
699034005780	NLPA lipoprotein; Region: Lipoprotein_9; cl19159
699034005781	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
699034005782	lipoyltransferase and lipoate-protein ligase; Region: lipoyltrans; TIGR00545
699034005783	Bacterial lipoate protein ligase C-terminus; Region: Lip_prot_lig_C; pfam10437
699034005784	Na+/H+ antiporter [Energy production and conversion]; Region: NhaC; COG1757
699034005785	glycine cleavage system aminomethyltransferase T; Reviewed; Region: gcvT; PRK00389
699034005786	Aminomethyltransferase folate-binding domain; Region: GCV_T; pfam01571
699034005787	Glycine cleavage T-protein C-terminal barrel domain; Region: GCV_T_C; pfam08669
699034005788	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
699034005789	tetramer interface [polypeptide binding]; other site
699034005790	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034005791	catalytic residue [active]
699034005792	Glycine cleavage system P-protein, alpha- and beta-subunits. This family consists of Glycine cleavage system P-proteins EC:1.4.4.2 from bacterial, mammalian and plant sources. The P protein is part of the glycine decarboxylase multienzyme complex EC:2.1; Region: GDC-P; cd00613
699034005793	tetramer interface [polypeptide binding]; other site
699034005794	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034005795	catalytic residue [active]
699034005796	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
699034005797	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
699034005798	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
699034005799	motif II; other site
699034005800	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
699034005801	Protein of unknown function (DUF1255); Region: DUF1255; pfam06865
699034005802	Domain of unknown function (DUF1835); Region: DUF1835; pfam08874
699034005803	Protein of unknown function; Region: DUF3658; pfam12395
699034005804	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
699034005805	guanine deaminase; Region: guan_deamin; TIGR02967
699034005806	active site
699034005807	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
699034005808	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034005809	non-specific DNA binding site [nucleotide binding]; other site
699034005810	salt bridge; other site
699034005811	sequence-specific DNA binding site [nucleotide binding]; other site
699034005812	Cupin domain; Region: Cupin_2; cl17218
699034005813	cysteine synthase; Region: PLN02565
699034005814	CBS_like: This subgroup includes Cystathionine beta-synthase (CBS) and Cysteine synthase. CBS is a unique heme-containing enzyme that catalyzes a pyridoxal 5'-phosphate (PLP)-dependent condensation of serine and homocysteine to give cystathionine; Region: CBS_like; cd01561
699034005815	dimer interface [polypeptide binding]; other site
699034005816	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034005817	catalytic residue [active]
699034005818	Membrane domain of glycerophosphoryl diester phosphodiesterase; Region: GPDPase_memb; pfam10110
699034005819	Glycerophosphoryl diester phosphodiesterase [Energy production and conversion]; Region: UgpQ; COG0584
699034005820	Glycerophosphodiester phosphodiesterase domain of uncharacterized bacterial glycerophosphodiester phosphodiesterases; Region: GDPD_memb_like; cd08579
699034005821	putative active site [active]
699034005822	catalytic site [active]
699034005823	putative metal binding site [ion binding]; other site
699034005824	maltose O-acetyltransferase; Provisional; Region: PRK10092
699034005825	Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6...; Region: LbH_MAT_GAT; cd03357
699034005826	active site
699034005827	substrate binding site [chemical binding]; other site
699034005828	trimer interface [polypeptide binding]; other site
699034005829	CoA binding site [chemical binding]; other site
699034005830	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
699034005831	ABC-type multidrug transport system, ATPase component; Region: ABC_drug_resistance_like; cd03264
699034005832	Walker A/P-loop; other site
699034005833	ATP binding site [chemical binding]; other site
699034005834	Q-loop/lid; other site
699034005835	ABC transporter signature motif; other site
699034005836	Walker B; other site
699034005837	D-loop; other site
699034005838	H-loop/switch region; other site
699034005839	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
699034005840	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034005841	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034005842	active site
699034005843	phosphorylation site [posttranslational modification]
699034005844	intermolecular recognition site; other site
699034005845	dimerization interface [polypeptide binding]; other site
699034005846	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034005847	DNA binding site [nucleotide binding]
699034005848	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034005849	HAMP domain; Region: HAMP; pfam00672
699034005850	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034005851	dimer interface [polypeptide binding]; other site
699034005852	phosphorylation site [posttranslational modification]
699034005853	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034005854	ATP binding site [chemical binding]; other site
699034005855	Mg2+ binding site [ion binding]; other site
699034005856	G-X-G motif; other site
699034005857	TraX protein; Region: TraX; cl05434
699034005858	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
699034005859	Predicted transcriptional regulators [Transcription]; Region: COG1733
699034005860	Pyroglutamyl peptidase (PGP) type I, also known as pyrrolidone carboxyl peptidase (pcp) type I:  Enzymes responsible for cleaving pyroglutamate (pGlu) from the N-terminal end of specialized proteins. The N-terminal pGlu protects these proteins from...; Region: Peptidase_C15; cd00501
699034005861	putative substrate binding pocket [chemical binding]; other site
699034005862	AC domain interface; other site
699034005863	catalytic triad [active]
699034005864	AB domain interface; other site
699034005865	interchain disulfide; other site
699034005866	Predicted membrane protein [Function unknown]; Region: COG3817
699034005867	Protein of unknown function (DUF979); Region: DUF979; pfam06166
699034005868	Protein of unknown function (DUF969); Region: DUF969; pfam06149
699034005869	Flavodoxin domain; Region: Flavodoxin_5; pfam12724
699034005870	FMN-binding domain; Region: FMN_bind; cl01081
699034005871	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
699034005872	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
699034005873	NH_3: A subgroup of nucleoside hydrolases. This group contains eukaryotic and bacterial proteins similar to nucleoside hydrolases. Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. These enzymes...; Region: nuc_hydro_3; cd02653
699034005874	active site
699034005875	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
699034005876	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl18962
699034005877	A new structural DNA glycosylase; Region: AlkD_like; cd06561
699034005878	active site
699034005879	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cl00309
699034005880	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034005881	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034005882	active site
699034005883	phosphorylation site [posttranslational modification]
699034005884	intermolecular recognition site; other site
699034005885	dimerization interface [polypeptide binding]; other site
699034005886	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034005887	DNA binding site [nucleotide binding]
699034005888	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034005889	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034005890	dimer interface [polypeptide binding]; other site
699034005891	phosphorylation site [posttranslational modification]
699034005892	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034005893	ATP binding site [chemical binding]; other site
699034005894	Mg2+ binding site [ion binding]; other site
699034005895	G-X-G motif; other site
699034005896	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
699034005897	catalytic residues [active]
699034005898	Thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]; Region: TrxB; COG0492
699034005899	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
699034005900	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
699034005901	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
699034005902	dimerization interface [polypeptide binding]; other site
699034005903	putative DNA binding site [nucleotide binding]; other site
699034005904	putative Zn2+ binding site [ion binding]; other site
699034005905	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
699034005906	This uncharacterized conserved protein belongs to a family of iron-molybdenum cluster-binding proteins that includes NifX, NifB, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of...; Region: MTH1175; cd00851
699034005907	Citrate transporter; Region: CitMHS; pfam03600
699034005908	Permease P (pink-eyed dilution). Mutations in the human melanosomal P gene were responsible for classic phenotype of oculocutaneous albinism type 2 (OCA2). Although the precise function of the P protein is unknown, it was predicted to regulate the...; Region: P_permease; cd01116
699034005909	transmembrane helices; other site
699034005910	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
699034005911	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
699034005912	homopentamer interface [polypeptide binding]; other site
699034005913	active site
699034005914	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311
699034005915	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
699034005916	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
699034005917	dimerization interface [polypeptide binding]; other site
699034005918	active site
699034005919	riboflavin synthase subunit alpha; Provisional; Region: PRK09289
699034005920	Lumazine binding domain; Region: Lum_binding; pfam00677
699034005921	Lumazine binding domain; Region: Lum_binding; pfam00677
699034005922	riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326
699034005923	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
699034005924	catalytic motif [active]
699034005925	Zn binding site [ion binding]; other site
699034005926	Pyrimidine reductase, riboflavin biosynthesis [Coenzyme metabolism]; Region: RibD; COG1985
699034005927	ATP-dependent DNA helicase RecQ; Region: recQ; TIGR01389
699034005928	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
699034005929	ATP binding site [chemical binding]; other site
699034005930	putative Mg++ binding site [ion binding]; other site
699034005931	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
699034005932	nucleotide binding region [chemical binding]; other site
699034005933	ATP-binding site [chemical binding]; other site
699034005934	This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure; Region: RQC; smart00956
699034005935	HRDC domain; Region: HRDC; pfam00570
699034005936	HRDC domain; Region: HRDC; pfam00570
699034005937	Helix-turn-helix domain; Region: HTH_40; pfam14493
699034005938	ThiC family; Region: ThiC; pfam01964
699034005939	thiamine biosynthesis protein ThiC; Region: thiC; TIGR00190
699034005940	ThiaminS ubiquitin-like sulfur carrier protein; Region: ThiS; cd00565
699034005941	thiS-thiF/thiG interaction site; other site
699034005942	ThiS-like ubiquitin; Region: ThiS-like; pfam14453
699034005943	thiamine biosynthesis protein ThiF; Provisional; Region: PRK08644
699034005944	Superfamily of activating enzymes (E1) of the ubiquitin-like proteins. This family includes classical ubiquitin-activating enzymes E1, ubiquitin-like (ubl) activating enzymes and other mechanistic homologes, like MoeB, Thif1 and others. The common...; Region: E1_enzyme_family; cl17196
699034005945	ATP binding site [chemical binding]; other site
699034005946	substrate interface [chemical binding]; other site
699034005947	Thiazole synthase (ThiG) is the tetrameric enzyme that is involved in the formation of the thiazole moiety of thiamin pyrophosphate, an essential ubiquitous cofactor that plays an important role in carbohydrate and amino acid metabolism. ThiG catalyzes...; Region: ThiG; cd04728
699034005948	ThiS interaction site; other site
699034005949	putative active site [active]
699034005950	tetramer interface [polypeptide binding]; other site
699034005951	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09240
699034005952	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
699034005953	FeS/SAM binding site; other site
699034005954	Biotin and Thiamin Synthesis associated domain; Region: BATS; pfam06968
699034005955	Thiamine monophosphate synthase (TMP synthase)/TenI. TMP synthase catalyzes an important step in the thiamine biosynthesis pathway, the substitution of the pyrophosphate of 2-methyl-4-amino-5- hydroxymethylpyrimidine pyrophosphate by 4-methyl-5-; Region: TMP_TenI; cd00564
699034005956	thiamine phosphate binding site [chemical binding]; other site
699034005957	active site
699034005958	pyrophosphate binding site [ion binding]; other site
699034005959	Predicted membrane protein [Function unknown]; Region: COG1288
699034005960	C4-dicarboxylate anaerobic carrier; Region: DcuC; pfam03606
699034005961	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
699034005962	synthetase active site [active]
699034005963	NTP binding site [chemical binding]; other site
699034005964	metal binding site [ion binding]; metal-binding site
699034005965	MobA catalyzes the formation of molybdopterin guanine dinucleotide; Region: MobA; cd02503
699034005966	GTP binding site; other site
699034005967	CoA binding domain; Region: CoA_binding_2; pfam13380
699034005968	hypothetical protein; Provisional; Region: PRK00967
699034005969	MogA_MoaB family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF) an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea; Region: MogA_MoaB; cd00886
699034005970	MPT binding site; other site
699034005971	trimer interface [polypeptide binding]; other site
699034005972	molybdenum cofactor biosynthesis protein A, bacterial; Region: moaA; TIGR02666
699034005973	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
699034005974	FeS/SAM binding site; other site
699034005975	Molybdenum Cofactor Synthesis C; Region: Mob_synth_C; pfam06463
699034005976	MoaC family, prokaryotic and eukaryotic. Members of this family are involved in molybdenum cofactor (Moco) biosynthesis, an essential cofactor of a diverse group of redox enzymes. MoaC, a small hexameric protein, converts, together with MoaA, a guanosine...; Region: MoaC_PE; cd01420
699034005977	trimer interface [polypeptide binding]; other site
699034005978	dimer interface [polypeptide binding]; other site
699034005979	putative active site [active]
699034005980	MOSC domain; Region: MOSC; pfam03473
699034005981	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
699034005982	Permease for cytosine/purines, uracil, thiamine, allantoin; Region: Transp_cyt_pur; pfam02133
699034005983	Na binding site [ion binding]; other site
699034005984	Protein of unknown function (DUF917); Region: DUF917; pfam06032
699034005985	N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism]; Region: HyuA; COG0145
699034005986	Hydantoinase/oxoprolinase N-terminal region; Region: Hydant_A_N; pfam05378
699034005987	Hydantoinase/oxoprolinase; Region: Hydantoinase_A; pfam01968
699034005988	Protein of unknown function (DUF1697); Region: DUF1697; pfam08002
699034005989	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
699034005990	putative acyl-acceptor binding pocket; other site
699034005991	Protein of unknown function (DUF3795); Region: DUF3795; pfam12675
699034005992	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
699034005993	Helix-turn-helix domain; Region: HTH_18; pfam12833
699034005994	Protein Kinases, catalytic domain; Region: PKc_like; cl09925
699034005995	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
699034005996	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
699034005997	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
699034005998	PhoU domain; Region: PhoU; pfam01895
699034005999	PhoU domain; Region: PhoU; pfam01895
699034006000	MRP (Multiple Resistance and pH adaptation) is a homologue of the Fer4_NifH superfamily. Like the other members of the superfamily, MRP contains a ATP-binding domain at the N-termini. It is found in bacteria as a membrane-spanning protein and functions...; Region: MRP-like; cd02037
699034006001	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Mrp; COG0489
699034006002	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
699034006003	Coenzyme A binding pocket [chemical binding]; other site
699034006004	Predicted cobalamin binding protein [General function prediction only]; Region: COG5012
699034006005	B12 binding domain (B12-BD). Most of the members bind different cobalamid derivates, like B12 (adenosylcobamide) or methylcobalamin or methyl-Co(III) 5-hydroxybenzimidazolylcobamide. This domain is found in several enzymes, such as glutamate mutase; Region: B12-binding_like; cl00293
699034006006	B12 binding site [chemical binding]; other site
699034006007	Uroporphyrinogen decarboxylase (URO-D); Region: URO-D; pfam01208
699034006008	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
699034006009	HAD-hyrolase-like; Region: Hydrolase_like; cl19142
699034006010	HAD superfamily (subfamily IA) hydrolase, TIGR02254; Region: YjjG/YfnB
699034006011	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
699034006012	motif II; other site
699034006013	DNA-binding transcriptional repressor PuuR; Provisional; Region: PRK09943
699034006014	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034006015	non-specific DNA binding site [nucleotide binding]; other site
699034006016	salt bridge; other site
699034006017	sequence-specific DNA binding site [nucleotide binding]; other site
699034006018	Cupin domain; Region: Cupin_2; pfam07883
699034006019	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
699034006020	fructuronate transporter; Provisional; Region: PRK10034; cl15264
699034006021	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
699034006022	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
699034006023	substrate binding pocket [chemical binding]; other site
699034006024	membrane-bound complex binding site; other site
699034006025	hinge residues; other site
699034006026	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
699034006027	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034006028	dimer interface [polypeptide binding]; other site
699034006029	phosphorylation site [posttranslational modification]
699034006030	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034006031	ATP binding site [chemical binding]; other site
699034006032	Mg2+ binding site [ion binding]; other site
699034006033	G-X-G motif; other site
699034006034	Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms]; Region: AtoC; COG2204
699034006035	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034006036	active site
699034006037	phosphorylation site [posttranslational modification]
699034006038	intermolecular recognition site; other site
699034006039	dimerization interface [polypeptide binding]; other site
699034006040	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034006041	Walker A motif; other site
699034006042	ATP binding site [chemical binding]; other site
699034006043	Walker B motif; other site
699034006044	arginine finger; other site
699034006045	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
699034006046	Glycine/sarcosine/betaine reductase component B subunits; Region: Gly_reductase; pfam09338
699034006047	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB); Region: GRDB; cl19416
699034006048	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB); Region: GRDB; cl19416
699034006049	Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918
699034006050	Sodium/glutamate symporter; Region: Glt_symporter; cl19414
699034006051	Adenosine deaminase (ADA) is a monomeric zinc dependent enzyme which catalyzes the irreversible hydrolytic deamination of both adenosine, as well as desoxyadenosine, to ammonia and inosine or desoxyinosine, respectively. ADA plays an important role in...; Region: ADA; cd01320
699034006052	active site
699034006053	purine riboside binding site [chemical binding]; other site
699034006054	EcsC protein family; Region: EcsC; pfam12787
699034006055	Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB [Amino acid transport and metabolism]; Region: HgdB; COG1775
699034006056	2-hydroxyglutaryl-CoA dehydratase, D-component; Region: HGD-D; pfam06050
699034006057	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
699034006058	C1 Peptidase family (MEROPS database nomenclature), also referred to as the papain family; composed of two subfamilies of cysteine peptidases (CPs), C1A (papain) and C1B (bleomycin hydrolase). Papain-like enzymes are mostly endopeptidases with some...; Region: Peptidase_C1; cd02619
699034006059	active site
699034006060	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034006061	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034006062	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034006063	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
699034006064	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
699034006065	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
699034006066	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
699034006067	Walker A/P-loop; other site
699034006068	ATP binding site [chemical binding]; other site
699034006069	Q-loop/lid; other site
699034006070	ABC transporter signature motif; other site
699034006071	Walker B; other site
699034006072	D-loop; other site
699034006073	H-loop/switch region; other site
699034006074	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
699034006075	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034006076	non-specific DNA binding site [nucleotide binding]; other site
699034006077	salt bridge; other site
699034006078	sequence-specific DNA binding site [nucleotide binding]; other site
699034006079	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
699034006080	active site
699034006081	catalytic residues [active]
699034006082	metal binding site [ion binding]; metal-binding site
699034006083	Pyrimidine dimer DNA glycosylase; Region: Pyr_excise; pfam03013
699034006084	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
699034006085	Radical SAM superfamily; Region: Radical_SAM; pfam04055
699034006086	FeS/SAM binding site; other site
699034006087	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
699034006088	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
699034006089	S-adenosylmethionine binding site [chemical binding]; other site
699034006090	tRNA-splicing ligase RtcB; Region: RtcB; pfam01139
699034006091	Flavodoxins [Energy production and conversion]; Region: FldA; COG0716
699034006092	RPB11 and RPB3 subunits of RNA polymerase; Region: RNAP_RPB11_RPB3; cl11409
699034006093	4Fe-4S dicluster domain; Region: Fer4_9; pfam13187
699034006094	potential frameshift: common BLAST hit: gi|300855122|ref|YP_003780106.1| epimerase
699034006095	Protein of unknown function (DUF2992); Region: DUF2992; pfam11208
699034006096	Protein of unknown function (DUF1294); Region: DUF1294; pfam06961
699034006097	B3/4 domain; Region: B3_4; cl19243
699034006098	ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+; Region: ADPRase_NUDT5; cd03424
699034006099	dimer interface [polypeptide binding]; other site
699034006100	ADP-ribose binding site [chemical binding]; other site
699034006101	active site
699034006102	nudix motif; other site
699034006103	metal binding site [ion binding]; metal-binding site
699034006104	Domain of unknown function (DUF4624); Region: DUF4624; pfam15417
699034006105	glyceraldehyde-3-phosphate dehydrogenase; Validated; Region: PRK07729
699034006106	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
699034006107	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
699034006108	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
699034006109	Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) [Lipid metabolism]; Region: COG1924
699034006110	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3580
699034006111	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3581
699034006112	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
699034006113	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
699034006114	DNA binding site [nucleotide binding]
699034006115	active site
699034006116	Putative redox-active protein (C_GCAxxG_C_C); Region: C_GCAxxG_C_C; pfam09719
699034006117	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
699034006118	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
699034006119	substrate binding pocket [chemical binding]; other site
699034006120	membrane-bound complex binding site; other site
699034006121	hinge residues; other site
699034006122	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
699034006123	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034006124	dimer interface [polypeptide binding]; other site
699034006125	conserved gate region; other site
699034006126	putative PBP binding loops; other site
699034006127	ABC-ATPase subunit interface; other site
699034006128	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
699034006129	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034006130	Walker A/P-loop; other site
699034006131	ATP binding site [chemical binding]; other site
699034006132	Q-loop/lid; other site
699034006133	ABC transporter signature motif; other site
699034006134	Walker B; other site
699034006135	D-loop; other site
699034006136	H-loop/switch region; other site
699034006137	Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX)...; Region: ArsC_like; cd03036
699034006138	putative ArsC-like catalytic residues; other site
699034006139	putative TRX-like catalytic residues [active]
699034006140	Domain of unknown function (DUF4253); Region: DUF4253; pfam14062
699034006141	ATP-utilizing enzymes of the PP-loop superfamily [General function prediction only]; Region: COG1606
699034006142	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily. Adenine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_I; cd01990
699034006143	Ligand Binding Site [chemical binding]; other site
699034006144	Predicted N6-adenine-specific DNA methylase [DNA replication, recombination, and repair]; Region: COG0116
699034006145	THUMP domain associated with S-adenosylmethionine-dependent methyltransferases; Region: THUMP_AdoMetMT; cd11715
699034006146	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
699034006147	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034006148	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034006149	active site
699034006150	phosphorylation site [posttranslational modification]
699034006151	intermolecular recognition site; other site
699034006152	dimerization interface [polypeptide binding]; other site
699034006153	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034006154	DNA binding site [nucleotide binding]
699034006155	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034006156	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
699034006157	dimerization interface [polypeptide binding]; other site
699034006158	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034006159	dimer interface [polypeptide binding]; other site
699034006160	phosphorylation site [posttranslational modification]
699034006161	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034006162	ATP binding site [chemical binding]; other site
699034006163	Mg2+ binding site [ion binding]; other site
699034006164	G-X-G motif; other site
699034006165	tRNA pseudouridine synthase A; Reviewed; Region: PRK12434
699034006166	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
699034006167	dimerization interface 3.5A [polypeptide binding]; other site
699034006168	active site
699034006169	argininosuccinate synthase; Provisional; Region: PRK13820
699034006170	Argininosuccinate synthase. The Argininosuccinate synthase is a urea cycle enzyme that catalyzes the penultimate step in arginine biosynthesis: the ATP-dependent ligation of citrulline to aspartate to form argininosuccinate, AMP and pyrophosphate .  In...; Region: Argininosuccinate_Synthase; cd01999
699034006171	ANP binding site [chemical binding]; other site
699034006172	Substrate Binding Site II [chemical binding]; other site
699034006173	Substrate Binding Site I [chemical binding]; other site
699034006174	A predicted NlpC/p60-like peptidase; Region: BtrH; pfam14399
699034006175	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
699034006176	Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106
699034006177	DNA binding residues [nucleotide binding]
699034006178	dimer interface [polypeptide binding]; other site
699034006179	TipAS antibiotic-recognition domain; Region: TipAS; pfam07739
699034006180	Domain of unknown function (DUF4363); Region: DUF4363; pfam14276
699034006181	Predicted membrane protein [Function unknown]; Region: COG2323
699034006182	DEDDh 3'-5' exonuclease domain of Caenorhabditis elegans ERI-1, human 3' exonuclease, and similar proteins; Region: ERI-1_3'hExo_like; cd06133
699034006183	active site
699034006184	catalytic site [active]
699034006185	substrate binding site [chemical binding]; other site
699034006186	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
699034006187	L-threonine dehydrogenase, extended (e) SDRs; Region: TDH_SDR_e; cd05272
699034006188	NAD binding site [chemical binding]; other site
699034006189	homodimer interface [polypeptide binding]; other site
699034006190	active site
699034006191	putative substrate binding site [chemical binding]; other site
699034006192	Putative redox-active protein (C_GCAxxG_C_C); Region: C_GCAxxG_C_C; pfam09719
699034006193	Domain of unknown function (DUF1883); Region: DUF1883; pfam08980
699034006194	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
699034006195	sulfite reductase, subunit C; Region: sulfite_red_C; TIGR02912
699034006196	Nitrite and sulphite reductase 4Fe-4S domain; Region: NIR_SIR; pfam01077
699034006197	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
699034006198	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
699034006199	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
699034006200	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
699034006201	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
699034006202	Rhodanese Homology Domain (RHOD); an alpha beta fold domain found duplicated in the rhodanese protein. The cysteine containing enzymatically active version of the domain is also found in the Cdc25 class of protein phosphatases and a variety of proteins...; Region: RHOD; cd00158
699034006203	active site residue [active]
699034006204	Transcriptional regulator [Transcription]; Region: LysR; COG0583
699034006205	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
699034006206	C-terminal substrate binding domain of LysR-type transcriptional regulator CysL, which activates the transcription of the cysJI operon encoding sulfite reductase, contains the type 2 periplasmic binding fold; Region: PBP2_CysL_like; cd08420
699034006207	putative dimerization interface [polypeptide binding]; other site
699034006208	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
699034006209	putative metal binding site [ion binding]; other site
699034006210	Uncharacterized proteins involved in stress response, similar to tellurium resistance terD; Region: TerD_like; cd06974
699034006211	putative metal binding site [ion binding]; other site
699034006212	Uncharacterized conserved protein [Function unknown]; Region: COG1284
699034006213	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
699034006214	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
699034006215	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
699034006216	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
699034006217	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034006218	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034006219	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034006220	Transcriptional regulators [Transcription]; Region: PurR; COG1609
699034006221	Helix-turn-helix (HTH) DNA binding domain of the LacI family of transcriptional regulators; Region: HTH_LacI; cd01392
699034006222	DNA binding site [nucleotide binding]
699034006223	domain linker motif; other site
699034006224	Ligand-binding domain of DNA transcription repressor specific for trehalose (TreR) which is a member of the LacI-GalR family of bacterial transcription regulators; Region: PBP1_TreR_like; cd01542
699034006225	dimerization interface [polypeptide binding]; other site
699034006226	ligand binding site [chemical binding]; other site
699034006227	sucrose-6-phosphate hydrolase; Region: scrB_fam; TIGR01322
699034006228	Glycosyl hydrolase family 32, beta-fructosidases; Region: GH32_B_Fructosidase; cd08996
699034006229	substrate binding [chemical binding]; other site
699034006230	active site
699034006231	Glycosyl hydrolases family 32 C terminal; Region: Glyco_hydro_32C; pfam08244
699034006232	Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into...; Region: bac_FRK; cd01167
699034006233	putative substrate binding site [chemical binding]; other site
699034006234	putative ATP binding site [chemical binding]; other site
699034006235	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
699034006236	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
699034006237	pyridoxal-dependent decarboxylase, exosortase A system-associated; Region: dCO2ase_PEP1; TIGR03099
699034006238	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
699034006239	catalytic residue [active]
699034006240	drug efflux system protein MdtG; Provisional; Region: PRK09874
699034006241	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
699034006242	putative substrate translocation pore; other site
699034006243	Penicillinase repressor; Region: Pencillinase_R; pfam03965
699034006244	LytTr DNA-binding domain; Region: LytTR; smart00850
699034006245	Protein of unknown function (DUF1653); Region: DUF1653; cl01949
699034006246	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
699034006247	catalytic core [active]
699034006248	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
699034006249	flavoprotein, HI0933 family; Region: TIGR00275
699034006250	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
699034006251	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
699034006252	cytidylate kinase; Provisional; Region: cmk; PRK00023
699034006253	AAA domain; Region: AAA_17; cl19128
699034006254	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
699034006255	CMP-binding site; other site
699034006256	The sites determining sugar specificity; other site
699034006257	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
699034006258	putative acyl-acceptor binding pocket; other site
699034006259	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Region: lytB_ispH; cd13944
699034006260	Fe-S cluster binding site [ion binding]; other site
699034006261	substrate binding site [chemical binding]; other site
699034006262	catalytic site [active]
699034006263	Protein of unknown function (DUF2899); Region: DUF2899; pfam11449
699034006264	Adenine deaminase [Nucleotide transport and metabolism]; Region: AdeC; COG1001
699034006265	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
699034006266	Adenine deaminase (AdeC) directly deaminates adenine to form hypoxanthine. This reaction is part of one of the adenine salvage pathways, as well as the degradation pathway. It is important for adenine utilization as a purine, as well as a nitrogen source...; Region: AdeC; cd01295
699034006267	active site
699034006268	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
699034006269	Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing...; Region: PRX_BCP; cd03017
699034006270	catalytic triad [active]
699034006271	Protein of unknown function (DUF328); Region: DUF328; pfam03883
699034006272	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
699034006273	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
699034006274	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
699034006275	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
699034006276	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
699034006277	motif II; other site
699034006278	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
699034006279	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
699034006280	homodimer interface [polypeptide binding]; other site
699034006281	substrate-cofactor binding pocket; other site
699034006282	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034006283	catalytic residue [active]
699034006284	Type 1 glutamine amidotransferase (GATase1)-like domain found in homoserine trans-succinylase (HTS); Region: GATase1_HTS; cd03131
699034006285	proposed active site lysine [active]
699034006286	conserved cys residue [active]
699034006287	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
699034006288	Transcriptional regulators [Transcription]; Region: MarR; COG1846
699034006289	putative DNA binding site [nucleotide binding]; other site
699034006290	putative Zn2+ binding site [ion binding]; other site
699034006291	FtsH Extracellular; Region: FtsH_ext; pfam06480
699034006292	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
699034006293	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034006294	Walker A motif; other site
699034006295	ATP binding site [chemical binding]; other site
699034006296	Walker B motif; other site
699034006297	arginine finger; other site
699034006298	Peptidase family M41; Region: Peptidase_M41; pfam01434
699034006299	Osmosensitive K+ channel histidine kinase [Signal transduction mechanisms]; Region: KdpD; COG2205
699034006300	Osmosensitive K+ channel His kinase sensor domain; Region: KdpD; pfam02702
699034006301	USP domain is located between the N-terminal sensor domain and C-terminal catalytic domain of this Osmosensitive K+ channel histidine kinase family. The family of KdpD sensor kinase proteins regulates the kdpFABC operon responsible for potassium...; Region: USP_OKCHK; cd01987
699034006302	Ligand Binding Site [chemical binding]; other site
699034006303	Domain of unknown function (DUF4118); Region: DUF4118; pfam13493
699034006304	GAF domain; Region: GAF_3; pfam13492
699034006305	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034006306	dimer interface [polypeptide binding]; other site
699034006307	phosphorylation site [posttranslational modification]
699034006308	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034006309	ATP binding site [chemical binding]; other site
699034006310	Mg2+ binding site [ion binding]; other site
699034006311	G-X-G motif; other site
699034006312	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034006313	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034006314	active site
699034006315	phosphorylation site [posttranslational modification]
699034006316	intermolecular recognition site; other site
699034006317	dimerization interface [polypeptide binding]; other site
699034006318	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034006319	DNA binding site [nucleotide binding]
699034006320	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
699034006321	metal ion transporter CorA-like divalent cation transporter superfamily; Region: MIT_CorA-like; cl00459
699034006322	oligomer interface [polypeptide binding]; other site
699034006323	3-deoxy-7-phosphoheptulonate synthase; Reviewed; Region: PRK08673
699034006324	phospho-2-dehydro-3-deoxyheptonate aldolase; Region: DAHP_synth_Bsub; TIGR01361
699034006325	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
699034006326	active site
699034006327	dimer interface [polypeptide binding]; other site
699034006328	metal binding site [ion binding]; metal-binding site
699034006329	3-phosphoshikimate 1-carboxyvinyltransferase; Provisional; Region: PRK02427
699034006330	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
699034006331	hinge; other site
699034006332	active site
699034006333	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
699034006334	Tetramer interface [polypeptide binding]; other site
699034006335	active site
699034006336	FMN-binding site [chemical binding]; other site
699034006337	Chorismate mutase type II; Region: CM_2; smart00830
699034006338	Prephenate dehydratase [Amino acid transport and metabolism]; Region: PheA; COG0077
699034006339	Prephenate dehydratase; Region: PDT; pfam00800
699034006340	C-terminal ACT domain of the bifunctional chorismate mutase-prephenate dehydratase (CM-PDT) enzyme and the prephenate dehydratase (PDT) enzyme; Region: ACT_CM-PDT; cd04905
699034006341	putative L-Phe binding site [chemical binding]; other site
699034006342	Shikimate 5-dehydrogenase [Amino acid transport and metabolism]; Region: AroE; COG0169
699034006343	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
699034006344	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
699034006345	shikimate binding site; other site
699034006346	NAD(P) binding site [chemical binding]; other site
699034006347	Shikimate kinase [Amino acid transport and metabolism]; Region: AroK; COG0703
699034006348	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
699034006349	ADP binding site [chemical binding]; other site
699034006350	magnesium binding site [ion binding]; other site
699034006351	putative shikimate binding site; other site
699034006352	prephenate dehydrogenase; Validated; Region: PRK08507
699034006353	Prephenate dehydrogenase; Region: PDH; pfam02153
699034006354	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
699034006355	metal binding site [ion binding]; metal-binding site
699034006356	nucleotidyl binding site; other site
699034006357	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
699034006358	Sensory domain of two-component sensor kinase; Region: Cache_3; pfam14827
699034006359	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
699034006360	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
699034006361	putative active site [active]
699034006362	heme pocket [chemical binding]; other site
699034006363	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
699034006364	FOG: PAS/PAC domain [Signal transduction mechanisms]; Region: AtoS; COG2202
699034006365	putative active site [active]
699034006366	heme pocket [chemical binding]; other site
699034006367	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
699034006368	putative active site [active]
699034006369	heme pocket [chemical binding]; other site
699034006370	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
699034006371	metal binding site [ion binding]; metal-binding site
699034006372	active site
699034006373	I-site; other site
699034006374	YdcF-like. YdcF-like is a large family of mainly bacterial proteins, with a few members found in fungi, plants, and archaea. Escherichia coli YdcF has been shown to bind S-adenosyl-L-methionine (AdoMet), but a biochemical function has not been...; Region: YdcF-like; cd06259
699034006375	putative active site [active]
699034006376	Pyridoxine 5'-phosphate (PNP) oxidase-like proteins; Region: PNPOx_like; cl00381
699034006377	Carboxypeptidase regulatory-like domain; Region: CarboxypepD_reg; pfam13620
699034006378	conserved repeat domain; Region: B_ant_repeat; TIGR01451
699034006379	S-layer domain [Cell envelope biogenesis, outer membrane]; Region: COG1361
699034006380	Domain of unknown function DUF11; Region: DUF11; pfam01345
699034006381	Domain of unknown function DUF11; Region: DUF11; pfam01345
699034006382	Domain of unknown function DUF11; Region: DUF11; pfam01345
699034006383	Domain of unknown function DUF11; Region: DUF11; pfam01345
699034006384	Domain of unknown function DUF11; Region: DUF11; pfam01345
699034006385	Domain of unknown function DUF11; Region: DUF11; pfam01345
699034006386	Domain of unknown function DUF11; Region: DUF11; pfam01345
699034006387	Cupin domain; Region: Cupin_2; pfam07883
699034006388	NMT1-like family; Region: NMT1_2; cl17432
699034006389	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
699034006390	Methyltransferase domain; Region: Methyltransf_31; pfam13847
699034006391	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
699034006392	S-adenosylmethionine binding site [chemical binding]; other site
699034006393	This CD includes bacterial (Agrobacterium tumefaciens and Caulobacter crescentus ProX, and Clostridium sticklandii PrdX) and eukaryotic (Plasmodium falciparum N-terminal ProRS editing domain) sequences. The C. sticklandii PrdX protein, a homolog of the...; Region: PrdX_deacylase; cd04335
699034006394	putative deacylase active site [active]
699034006395	YtxH-like protein; Region: YtxH; pfam12732
699034006396	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
699034006397	active site
699034006398	metal binding site [ion binding]; metal-binding site
699034006399	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
699034006400	catalytic motif [active]
699034006401	Zn binding site [ion binding]; other site
699034006402	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
699034006403	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034006404	non-specific DNA binding site [nucleotide binding]; other site
699034006405	salt bridge; other site
699034006406	sequence-specific DNA binding site [nucleotide binding]; other site
699034006407	Signal peptidase (SPase) II; Region: Peptidase_A8; cl00458
699034006408	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
699034006409	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034006410	dimer interface [polypeptide binding]; other site
699034006411	conserved gate region; other site
699034006412	putative PBP binding loops; other site
699034006413	ABC-ATPase subunit interface; other site
699034006414	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
699034006415	Serine Recombinase family, catalytic domain; a DNA binding domain may be present either N- or C-terminal to the catalytic domain. These enzymes perform site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining...; Region: Ser_Recombinase; cd00338
699034006416	catalytic residues [active]
699034006417	catalytic nucleophile [active]
699034006418	Recombinase; Region: Recombinase; pfam07508
699034006419	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
699034006420	1,3-propanediol dehydrogenase (PPD) catalyzes the reduction of 3-hydroxypropionaldehyde (3-HPA) to 1,3-propanediol in glycerol metabolism; Region: PDD; cd08180
699034006421	putative active site [active]
699034006422	metal binding site [ion binding]; metal-binding site
699034006423	1,2-propanediol utilization protein U (PduU)/ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduU-EutS; cd07046
699034006424	putative hexamer interface [polypeptide binding]; other site
699034006425	putative hexagonal pore; other site
699034006426	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
699034006427	G1 box; other site
699034006428	GTP/Mg2+ binding site [chemical binding]; other site
699034006429	G2 box; other site
699034006430	Switch I region; other site
699034006431	G3 box; other site
699034006432	Switch II region; other site
699034006433	G4 box; other site
699034006434	G5 box; other site
699034006435	Response regulator with putative antiterminator output domain [Signal transduction mechanisms]; Region: AmiR; COG3707
699034006436	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034006437	active site
699034006438	phosphorylation site [posttranslational modification]
699034006439	intermolecular recognition site; other site
699034006440	dimerization interface [polypeptide binding]; other site
699034006441	ANTAR domain; Region: ANTAR; pfam03861
699034006442	Signal transduction histidine kinase; Region: H_kinase_N; pfam12282
699034006443	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
699034006444	Histidine kinase; Region: HisKA_2; pfam07568
699034006445	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034006446	ATP binding site [chemical binding]; other site
699034006447	Mg2+ binding site [ion binding]; other site
699034006448	G-X-G motif; other site
699034006449	Ethanolamine utilisation protein EutA; Region: EutA; pfam06277
699034006450	ethanolamine ammonia lyase large subunit; Provisional; Region: PRK15067
699034006451	Ethanolamine ammonia-lyase, small subunit [Amino acid transport and metabolism]; Region: EutC; COG4302
699034006452	ethanolamine utilization protein EutL; Provisional; Region: PRK15405
699034006453	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_EutL_repeat1; cd07049
699034006454	putative hexamer interface [polypeptide binding]; other site
699034006455	putative hexagonal pore; other site
699034006456	ethanolamine utilization protein S (EutS), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_EutL_repeat2; cd07050
699034006457	putative hexamer interface [polypeptide binding]; other site
699034006458	putative hexagonal pore; other site
699034006459	Carbon dioxide concentrating mechanism K (CcmK)-like proteins, Bacterial Micro-Compartment (BMC) domain; Region: BMC_CcmK_like; cd07045
699034006460	Hexamer interface [polypeptide binding]; other site
699034006461	Hexagonal pore residue; other site
699034006462	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
699034006463	putative catalytic cysteine [active]
699034006464	Carbon dioxide concentrating mechanism/carboxysome shell protein [Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion]; Region: CcmK; COG4577
699034006465	1,2-propanediol utilization protein A (PduA), Bacterial Micro-Compartment (BMC) domain; Region: BMC_PduA; cd07059
699034006466	Hexamer interface [polypeptide binding]; other site
699034006467	Putative hexagonal pore residue; other site
699034006468	Cobalamin adenosyltransferase; Region: Cob_adeno_trans; cl00920
699034006469	propanediol utilization phosphotransacylase; Provisional; Region: PRK15070
699034006470	Propanediol utilisation protein PduL; Region: PduL; pfam06130
699034006471	Propanediol utilisation protein PduL; Region: PduL; pfam06130
699034006472	ethanolamine utilization protein; Region: eut_hyp; TIGR02536
699034006473	Ethanolamine utilisation protein and carboxysome structural protein domain family; Region: EutN_CcmL; cd01614
699034006474	Hexamer/Pentamer interface [polypeptide binding]; other site
699034006475	central pore; other site
699034006476	PduT-like ethanolamine utilization protein; Region: eut_PduT; TIGR02526
699034006477	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 1; Region: BMC_PduT_repeat1; cd07053
699034006478	putative hexamer interface [polypeptide binding]; other site
699034006479	putative hexagonal pore; other site
699034006480	1,2-propanediol utilization protein T (PduT), Bacterial Micro-Compartment (BMC) domain repeat 2; Region: BMC_PduT_repeat2; cd07054
699034006481	putative hexamer interface [polypeptide binding]; other site
699034006482	putative hexagonal pore; other site
699034006483	Ethanolamine utilisation protein, EutH; Region: EutH; pfam04346
699034006484	Ethanolamine utilisation protein EutQ; Region: EutQ; pfam06249
699034006485	ethanolamine utilization protein EutQ; Provisional; Region: PRK15457
699034006486	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
699034006487	putative DNA binding site [nucleotide binding]; other site
699034006488	putative Zn2+ binding site [ion binding]; other site
699034006489	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
699034006490	M20 Peptidase Aminoacylase 1 subfamily; Region: M20_Acy1_subfamily5; cd08019
699034006491	metal binding site [ion binding]; metal-binding site
699034006492	putative dimer interface [polypeptide binding]; other site
699034006493	Putative p-aminobenzoyl-glutamate transporter [Coenzyme metabolism]; Region: AbgT; COG2978
699034006494	putative C-S lyase; Region: C_S_lyase_PatB; TIGR04350
699034006495	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
699034006496	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034006497	homodimer interface [polypeptide binding]; other site
699034006498	catalytic residue [active]
699034006499	Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG4181
699034006500	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034006501	Walker A/P-loop; other site
699034006502	ATP binding site [chemical binding]; other site
699034006503	Q-loop/lid; other site
699034006504	ABC transporter signature motif; other site
699034006505	Walker B; other site
699034006506	D-loop; other site
699034006507	H-loop/switch region; other site
699034006508	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
699034006509	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
699034006510	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
699034006511	ligand binding site [chemical binding]; other site
699034006512	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
699034006513	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
699034006514	LexA repressor; Validated; Region: PRK00215
699034006515	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
699034006516	putative DNA binding site [nucleotide binding]; other site
699034006517	Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC...; Region: S24_LexA-like; cd06529
699034006518	Catalytic site [active]
699034006519	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
699034006520	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
699034006521	active site
699034006522	DNA binding site [nucleotide binding]
699034006523	Int/Topo IB signature motif; other site
699034006524	Uncharacterized conserved protein [Function unknown]; Region: COG3603
699034006525	ACT domains C-terminal to the catalytic domain of aspartokinase (AK; 4-L-aspartate-4-phosphotransferase); Region: ACT_AK-like; cd04868
699034006526	Stage V sporulation protein S (SpoVS); Region: SpoVS; pfam04232
699034006527	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
699034006528	Acetyl co-enzyme A carboxylase carboxyltransferase alpha subunit; Region: ACCA; cl19172
699034006529	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
699034006530	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
699034006531	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
699034006532	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
699034006533	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
699034006534	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
699034006535	carboxyltransferase (CT) interaction site; other site
699034006536	biotinylation site [posttranslational modification]; other site
699034006537	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
699034006538	S-adenosylmethionine binding site [chemical binding]; other site
699034006539	Iron-sulphur cluster biosynthesis; Region: Fe-S_biosyn; cl00400
699034006540	This domain superfamily is found in a variety of structurally related metalloproteins, including the type I extradiol dioxygenases, glyoxalase I and a group of antibiotic resistance proteins; Region: Glo_EDI_BRP_like; cd06587
699034006541	active site
699034006542	metal binding site [ion binding]; metal-binding site
699034006543	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_23; cd09011
699034006544	Helix-turn-helix domain; Region: HTH_18; pfam12833
699034006545	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
699034006546	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
699034006547	Walker A/P-loop; other site
699034006548	ATP binding site [chemical binding]; other site
699034006549	Q-loop/lid; other site
699034006550	ABC transporter signature motif; other site
699034006551	Walker B; other site
699034006552	D-loop; other site
699034006553	H-loop/switch region; other site
699034006554	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
699034006555	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
699034006556	FtsX-like permease family; Region: FtsX; pfam02687
699034006557	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
699034006558	FtsX-like permease family; Region: FtsX; pfam02687
699034006559	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034006560	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034006561	dimer interface [polypeptide binding]; other site
699034006562	phosphorylation site [posttranslational modification]
699034006563	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034006564	ATP binding site [chemical binding]; other site
699034006565	Mg2+ binding site [ion binding]; other site
699034006566	G-X-G motif; other site
699034006567	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
699034006568	Uncharacterized conserved protein [Function unknown]; Region: COG1284
699034006569	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
699034006570	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
699034006571	Acetyltransferase (GNAT) family; Region: Acetyltransf_1; pfam00583
699034006572	Coenzyme A binding pocket [chemical binding]; other site
699034006573	Transcriptional regulator [Transcription]; Region: LysR; COG0583
699034006574	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
699034006575	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
699034006576	dimerization interface [polypeptide binding]; other site
699034006577	F420-0:Gamma-glutamyl ligase; Region: F420_ligase; pfam01996
699034006578	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
699034006579	FtsX-like permease family; Region: FtsX; pfam02687
699034006580	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
699034006581	FtsX-like permease family; Region: FtsX; pfam02687
699034006582	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
699034006583	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
699034006584	Walker A/P-loop; other site
699034006585	ATP binding site [chemical binding]; other site
699034006586	Q-loop/lid; other site
699034006587	ABC transporter signature motif; other site
699034006588	Walker B; other site
699034006589	D-loop; other site
699034006590	H-loop/switch region; other site
699034006591	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034006592	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034006593	dimer interface [polypeptide binding]; other site
699034006594	phosphorylation site [posttranslational modification]
699034006595	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034006596	ATP binding site [chemical binding]; other site
699034006597	Mg2+ binding site [ion binding]; other site
699034006598	G-X-G motif; other site
699034006599	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034006600	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034006601	active site
699034006602	phosphorylation site [posttranslational modification]
699034006603	intermolecular recognition site; other site
699034006604	dimerization interface [polypeptide binding]; other site
699034006605	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034006606	DNA binding site [nucleotide binding]
699034006607	Reductive dehalogenase subunit; Region: Dehalogenase; pfam13486
699034006608	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
699034006609	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
699034006610	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034006611	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034006612	active site
699034006613	phosphorylation site [posttranslational modification]
699034006614	intermolecular recognition site; other site
699034006615	dimerization interface [polypeptide binding]; other site
699034006616	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034006617	DNA binding site [nucleotide binding]
699034006618	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034006619	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034006620	dimer interface [polypeptide binding]; other site
699034006621	phosphorylation site [posttranslational modification]
699034006622	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034006623	ATP binding site [chemical binding]; other site
699034006624	Mg2+ binding site [ion binding]; other site
699034006625	G-X-G motif; other site
699034006626	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
699034006627	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
699034006628	Walker A/P-loop; other site
699034006629	ATP binding site [chemical binding]; other site
699034006630	Q-loop/lid; other site
699034006631	ABC transporter signature motif; other site
699034006632	Walker B; other site
699034006633	D-loop; other site
699034006634	H-loop/switch region; other site
699034006635	ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane]; Region: LolE; COG4591
699034006636	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
699034006637	FtsX-like permease family; Region: FtsX; pfam02687
699034006638	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
699034006639	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
699034006640	FtsX-like permease family; Region: FtsX; pfam02687
699034006641	Methyltransferase domain; Region: Methyltransf_31; pfam13847
699034006642	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
699034006643	S-adenosylmethionine binding site [chemical binding]; other site
699034006644	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
699034006645	WHG domain; Region: WHG; pfam13305
699034006646	Sulfate transporter family; Region: Sulfate_transp; cl19250
699034006647	Acyl-CoA thioester hydrolase/BAAT N-terminal region; Region: Bile_Hydr_Trans; pfam04775
699034006648	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
699034006649	BAAT / Acyl-CoA thioester hydrolase C terminal; Region: BAAT_C; pfam08840
699034006650	Protein of unknown function (DUF554); Region: DUF554; pfam04474
699034006651	This CD includes bacterial (Agrobacterium tumefaciens and Caulobacter crescentus ProX, and Clostridium sticklandii PrdX) and eukaryotic (Plasmodium falciparum N-terminal ProRS editing domain) sequences. The C. sticklandii PrdX protein, a homolog of the...; Region: PrdX_deacylase; cd04335
699034006652	putative deacylase active site [active]
699034006653	Kynurenine formamidase [Amino acid transport and metabolism]; Region: COG1878
699034006654	SIR2 superfamily of proteins includes silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation, where the acetyl group from the lysine epsilon-amino group is transferred to the ADP-ribose moiety of NAD+; Region: SIR2; cl00195
699034006655	hypothetical protein; Provisional; Region: PRK07205
699034006656	M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides; Region: M20_PepV; cd03888
699034006657	active site
699034006658	metal binding site [ion binding]; metal-binding site
699034006659	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl18945
699034006660	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
699034006661	catalytic residue [active]
699034006662	bacterial Hfq-like; Region: Hfq; cd01716
699034006663	hexamer interface [polypeptide binding]; other site
699034006664	Sm1 motif; other site
699034006665	RNA binding site [nucleotide binding]; other site
699034006666	Sm2 motif; other site
699034006667	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
699034006668	DNA mismatch repair protein; Reviewed; Region: mutL; PRK00095
699034006669	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034006670	ATP binding site [chemical binding]; other site
699034006671	Mg2+ binding site [ion binding]; other site
699034006672	G-X-G motif; other site
699034006673	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
699034006674	ATP binding site [chemical binding]; other site
699034006675	MutL C terminal dimerisation domain; Region: MutL_C; smart00853
699034006676	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
699034006677	MutS domain I; Region: MutS_I; pfam01624
699034006678	MutS domain II; Region: MutS_II; pfam05188
699034006679	MutS domain III; Region: MutS_III; pfam05192
699034006680	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
699034006681	Walker A/P-loop; other site
699034006682	ATP binding site [chemical binding]; other site
699034006683	Q-loop/lid; other site
699034006684	ABC transporter signature motif; other site
699034006685	Walker B; other site
699034006686	D-loop; other site
699034006687	H-loop/switch region; other site
699034006688	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
699034006689	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
699034006690	Walker A/P-loop; other site
699034006691	ATP binding site [chemical binding]; other site
699034006692	Q-loop/lid; other site
699034006693	ABC transporter signature motif; other site
699034006694	Walker B; other site
699034006695	D-loop; other site
699034006696	H-loop/switch region; other site
699034006697	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
699034006698	NMT1/THI5 like; Region: NMT1; pfam09084
699034006699	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
699034006700	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034006701	dimer interface [polypeptide binding]; other site
699034006702	conserved gate region; other site
699034006703	putative PBP binding loops; other site
699034006704	ABC-ATPase subunit interface; other site
699034006705	Domain of unknown function DUF77; Region: DUF77; pfam01910
699034006706	Predicted transcriptional regulators [Transcription]; Region: COG1733
699034006707	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
699034006708	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
699034006709	Probable transposase; Region: OrfB_IS605; pfam01385
699034006710	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
699034006711	potential frameshift: common BLAST hit: gi|300854958|ref|YP_003779942.1| epimerase
699034006712	Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyze the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative...; Region: CoAse; cd03426
699034006713	putative active site [active]
699034006714	putative CoA binding site [chemical binding]; other site
699034006715	nudix motif; other site
699034006716	metal binding site [ion binding]; metal-binding site
699034006717	Domain of unknown function (DUF3784); Region: DUF3784; pfam12650
699034006718	(dimethylallyl)adenosine tRNA methylthiotransferase; Provisional; Region: PRK14328
699034006719	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
699034006720	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
699034006721	FeS/SAM binding site; other site
699034006722	TRAM domain; Region: TRAM; pfam01938
699034006723	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034006724	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034006725	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034006726	metal ion transporter CorA-like divalent cation transporter superfamily; Region: MIT_CorA-like; cl00459
699034006727	Bacterial SH3 domain; Region: SH3_3; pfam08239
699034006728	Bacterial SH3 domain; Region: SH3_3; pfam08239
699034006729	Penicillinase repressor; Region: Penicillinase_R; cl17580
699034006730	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
699034006731	DNA-binding site [nucleotide binding]; DNA binding site
699034006732	RNA-binding motif; other site
699034006733	Predicted ATP-binding protein involved in virulence [General function prediction only]; Region: COG3950
699034006734	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
699034006735	NTF2-like N-terminal transpeptidase domain; Region: MecA_N; pfam05223
699034006736	type IV pilus biogenesis/stability protein PilW; Region: type_IV_pilW; TIGR02521
699034006737	Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit [Function unknown]; Region: COG0599
699034006738	Predicted integral membrane protein [Function unknown]; Region: COG5658
699034006739	Protein of unknown function (DUF1648); Region: DUF1648; pfam07853
699034006740	SdpI/YhfL protein family; Region: SdpI; pfam13630
699034006741	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
699034006742	dimerization interface [polypeptide binding]; other site
699034006743	putative DNA binding site [nucleotide binding]; other site
699034006744	putative Zn2+ binding site [ion binding]; other site
699034006745	hypothetical protein; Provisional; Region: PRK10621
699034006746	Cupin domain; Region: Cupin_2; cl17218
699034006747	Sensory domain found in PocR; Region: PocR; pfam10114
699034006748	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
699034006749	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
699034006750	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
699034006751	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
699034006752	DNA binding residues [nucleotide binding]
699034006753	putative dimer interface [polypeptide binding]; other site
699034006754	HpcH/HpaI aldolase/citrate lyase family; Region: HpcH_HpaI; cl17231
699034006755	Uncharacterized flavoproteins [Energy production and conversion]; Region: FpaA; COG0426
699034006756	flavodoxin, short chain; Region: flav_short; TIGR01753
699034006757	Peptidase S8 family domain in Subtilisin proteins; Region: Peptidases_S8_Subtilisin_subset; cd07477
699034006758	Subtilase family; Region: Peptidase_S8; pfam00082
699034006759	active site
699034006760	catalytic residues [active]
699034006761	dihydroxy-acid dehydratase; Provisional; Region: PRK00911
699034006762	VanZ like family; Region: VanZ; pfam04892
699034006763	L-aspartate oxidase; Provisional; Region: PRK06175
699034006764	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034006765	non-specific DNA binding site [nucleotide binding]; other site
699034006766	salt bridge; other site
699034006767	sequence-specific DNA binding site [nucleotide binding]; other site
699034006768	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
699034006769	AraC-type DNA-binding domain-containing proteins [Transcription]; Region: AraC; COG2207
699034006770	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
699034006771	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
699034006772	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
699034006773	Major Facilitator Superfamily; Region: MFS_1; pfam07690
699034006774	putative substrate translocation pore; other site
699034006775	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
699034006776	Clp amino terminal domain; Region: Clp_N; pfam02861
699034006777	Clp amino terminal domain; Region: Clp_N; pfam02861
699034006778	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034006779	Walker A motif; other site
699034006780	ATP binding site [chemical binding]; other site
699034006781	Walker B motif; other site
699034006782	arginine finger; other site
699034006783	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034006784	Walker A motif; other site
699034006785	ATP binding site [chemical binding]; other site
699034006786	Walker B motif; other site
699034006787	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
699034006788	Firmicute plasmid replication protein (RepL); Region: RepL; pfam05732
699034006789	Predicted transcriptional regulators [Transcription]; Region: COG1725
699034006790	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
699034006791	DNA-binding site [nucleotide binding]; DNA binding site
699034006792	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
699034006793	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
699034006794	Walker A/P-loop; other site
699034006795	ATP binding site [chemical binding]; other site
699034006796	Q-loop/lid; other site
699034006797	ABC transporter signature motif; other site
699034006798	Walker B; other site
699034006799	D-loop; other site
699034006800	H-loop/switch region; other site
699034006801	ABC-2 family transporter protein; Region: ABC2_membrane_5; pfam13346
699034006802	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
699034006803	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
699034006804	Coenzyme A binding pocket [chemical binding]; other site
699034006805	allantoate amidohydrolase; Reviewed; Region: PRK09290
699034006806	M20 Peptidase beta-alanine synthase, an amidohydrolase; Region: M20_bAS; cd03884
699034006807	active site
699034006808	metal binding site [ion binding]; metal-binding site
699034006809	dimer interface [polypeptide binding]; other site
699034006810	Asp/Glu/Hydantoin racemase; Region: Asp_Glu_race; cl00518
699034006811	ornithine carbamoyltransferase; Validated; Region: PRK02102
699034006812	Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain; Region: OTCace_N; pfam02729
699034006813	Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain; Region: OTCace; pfam00185
699034006814	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
699034006815	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161
699034006816	inhibitor-cofactor binding pocket; inhibition site
699034006817	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034006818	catalytic residue [active]
699034006819	AAK_NAGK-C: N-Acetyl-L-glutamate kinase - cyclic (NAGK-C) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of arginine biosynthesis found in some bacteria and photosynthetic organisms using the...; Region: AAK_NAGK-C; cd04250
699034006820	feedback inhibition sensing region; other site
699034006821	homohexameric interface [polypeptide binding]; other site
699034006822	nucleotide binding site [chemical binding]; other site
699034006823	N-acetyl-L-glutamate binding site [chemical binding]; other site
699034006824	Ornithine acetyltransferase (OAT) family; also referred to as ArgJ. OAT catalyzes the first and fifth steps in arginine biosynthesis, coupling acetylation of glutamate with deacetylation of N-acetylornithine, which allows recycling of the acetyl group in...; Region: OAT; cd02152
699034006825	heterotetramer interface [polypeptide binding]; other site
699034006826	active site pocket [active]
699034006827	cleavage site
699034006828	N-acetyl-gamma-glutamyl-phosphate reductase; Validated; Region: argC; PRK00436
699034006829	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
699034006830	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; cl19935
699034006831	conjugal transfer protein TrbB; Provisional; Region: PRK13728; cl17283
699034006832	YoaP-like; Region: YoaP; pfam14268
699034006833	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
699034006834	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
699034006835	Coenzyme A binding pocket [chemical binding]; other site
699034006836	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
699034006837	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
699034006838	Bacterial regulatory proteins, tetR family; Region: TetR_N; cl19382
699034006839	WHG domain; Region: WHG; pfam13305
699034006840	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
699034006841	Protein of unknown function (DUF2975); Region: DUF2975; pfam11188
699034006842	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034006843	salt bridge; other site
699034006844	non-specific DNA binding site [nucleotide binding]; other site
699034006845	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
699034006846	sequence-specific DNA binding site [nucleotide binding]; other site
699034006847	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
699034006848	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
699034006849	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
699034006850	putative active site [active]
699034006851	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
699034006852	Putative rRNA methylase; Region: rRNA_methylase; pfam06962
699034006853	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
699034006854	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
699034006855	RNA binding surface [nucleotide binding]; other site
699034006856	Pseudouridine synthases, RsuA subfamily; Region: PseudoU_synth_RsuA_like; cd02870
699034006857	active site
699034006858	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
699034006859	outer membrane assembly lipoprotein YfiO; Region: OM_YfiO; TIGR03302
699034006860	diaminopimelate decarboxylase; Region: lysA; TIGR01048
699034006861	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Diaminopimelate Decarboxylase; Region: PLPDE_III_DapDC; cd06828
699034006862	active site
699034006863	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
699034006864	substrate binding site [chemical binding]; other site
699034006865	catalytic residues [active]
699034006866	dimer interface [polypeptide binding]; other site
699034006867	aspartate kinase; Reviewed; Region: PRK06635
699034006868	AAK_AKii-LysC-BS: Amino Acid Kinase Superfamily (AAK), AKii; this CD includes the N-terminal catalytic aspartokinase (AK) domain of the lysine-sensitive aspartokinase isoenzyme AKII of Bacillus subtilis 168, and the lysine plus threonine-sensitive...; Region: AAK_AKii-LysC-BS; cd04261
699034006869	putative nucleotide binding site [chemical binding]; other site
699034006870	putative catalytic residues [active]
699034006871	putative Mg ion binding site [ion binding]; other site
699034006872	putative aspartate binding site [chemical binding]; other site
699034006873	ACT domains of the lysine-sensitive aspartokinase isoenzyme AKII and related proteins; Region: ACT_AK-LysC-DapG-like_1; cd04891
699034006874	ACT domains of the lysine-sensitive, aspartokinase (AK) isoenzyme AKII of Bacillus subtilis (BS) strain 168 and related domains; Region: ACT_AKii-LysC-BS-like_2; cd04936
699034006875	putative allosteric regulatory residue; other site
699034006876	glutaminyl-tRNA synthetase; Provisional; Region: PRK05347
699034006877	catalytic core domain of glutaminyl-tRNA synthetase; Region: GlnRS_core; cd00807
699034006878	active site
699034006879	HIGH motif; other site
699034006880	KMSKS motif; other site
699034006881	tRNA synthetases class I (E and Q), anti-codon binding domain; Region: tRNA-synt_1c_C; pfam03950
699034006882	putative lipid kinase; Reviewed; Region: PRK13059
699034006883	Diacylglycerol kinase catalytic domain; Region: DAGK_cat; pfam00781
699034006884	Uncharacterized ACR, YkgG family COG1556; Region: DUF162; pfam02589
699034006885	Protein of unknown function (DUF4003); Region: DUF4003; pfam13170
699034006886	Penicillinase repressor; Region: Penicillinase_R; cl17580
699034006887	AP2-like DNA-binding integrase domain; Region: Integrase_AP2; pfam14657
699034006888	Phage integrase, N-terminal SAM-like domain; Region: Phage_int_SAM_3; pfam14659
699034006889	tyrosine recombinase XerC; Region: recomb_XerC; TIGR02224
699034006890	phiLC3 phage and phage-related integrases, site-specific recombinases, DNA breaking-rejoining enzymes, C-terminal catalytic domain. This CD includes various bacterial (mainly gram positive) and phage integrases, including those similar to Lactococcus...; Region: INT_phiLC3_C; cd01189
699034006891	Int/Topo IB signature motif; other site
699034006892	ABC transporter ATP-binding protein; Provisional; Region: PRK15064
699034006893	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034006894	Walker A/P-loop; other site
699034006895	ATP binding site [chemical binding]; other site
699034006896	ABC transporter signature motif; other site
699034006897	Walker B; other site
699034006898	D-loop; other site
699034006899	H-loop/switch region; other site
699034006900	ABC transporter; Region: ABC_tran_2; pfam12848
699034006901	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
699034006902	MoeA_like. This domain is similar to a domain found in a variety of proteins involved in biosynthesis of molybdopterin cofactor, like MoaB, MogA, and MoeA. There this domain is presumed to bind molybdopterin. The exact function of this subgroup is...; Region: MoeA_like; cd03522
699034006903	putative MPT binding site; other site
699034006904	GT_2_like_f is a subfamily of the glycosyltransferase family 2 (GT-2) with unknown function; Region: GT_2_like_f; cd04182
699034006905	Ligand binding site; other site
699034006906	metal-binding site
699034006907	probable selenium-dependent hydroxylase accessory protein YqeC; Region: TIGR03172
699034006908	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
699034006909	Probable transposase; Region: OrfB_IS605; pfam01385
699034006910	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
699034006911	xanthine dehydrogenase subunit XdhA; Provisional; Region: PRK09970
699034006912	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
699034006913	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
699034006914	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]; Region: CoxM; COG1319
699034006915	FAD binding domain; Region: FAD_binding_4; cl19922
699034006916	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
699034006917	Sulfate transporter family; Region: Sulfate_transp; cl19250
699034006918	xanthine permease; Region: pbuX; TIGR03173
699034006919	Golgi complex component 7 (COG7); Region: COG7; pfam10191
699034006920	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
699034006921	dihydropyrimidine dehydrogenase subunit B; Validated; Region: PRK08318
699034006922	phosphate binding site [ion binding]; other site
699034006923	putative chlorohydrolase/aminohydrolase; Validated; Region: PRK07203
699034006924	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
699034006925	active site
699034006926	xanthine dehydrogenase subunit XdhA; Provisional; Region: PRK09970
699034006927	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
699034006928	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
699034006929	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]; Region: CoxM; COG1319
699034006930	FAD binding domain; Region: FAD_binding_4; cl19922
699034006931	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
699034006932	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
699034006933	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
699034006934	catalytic loop [active]
699034006935	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
699034006936	iron binding site [ion binding]; other site
699034006937	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
699034006938	N-ethylammeline chlorohydrolase; Provisional; Region: PRK07228
699034006939	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
699034006940	active site
699034006941	putative substrate binding pocket [chemical binding]; other site
699034006942	phenylhydantoinase; Validated; Region: PRK08323
699034006943	D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine...; Region: D-HYD; cd01314
699034006944	tetramer interface [polypeptide binding]; other site
699034006945	active site
699034006946	peptidase; Reviewed; Region: PRK13004
699034006947	M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like4; cd05649
699034006948	putative metal binding site [ion binding]; other site
699034006949	putative dimer interface [polypeptide binding]; other site
699034006950	Threonine dehydratase [Amino acid transport and metabolism]; Region: IlvA; COG1171
699034006951	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640
699034006952	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
699034006953	catalytic residue [active]
699034006954	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
699034006955	NADPH-dependent FMN reductase; Region: FMN_red; pfam03358
699034006956	xanthine dehydrogenase subunit XdhA; Provisional; Region: PRK09970
699034006957	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
699034006958	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
699034006959	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
699034006960	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
699034006961	catalytic loop [active]
699034006962	iron binding site [ion binding]; other site
699034006963	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
699034006964	N-ethylammeline chlorohydrolase; Provisional; Region: PRK06038
699034006965	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
699034006966	active site
699034006967	putative substrate binding pocket [chemical binding]; other site
699034006968	Sulfate transporter family; Region: Sulfate_transp; cl19250
699034006969	xanthine permease; Region: pbuX; TIGR03173
699034006970	Sulfate transporter family; Region: Sulfate_transp; cl19250
699034006971	xanthine permease; Region: pbuX; TIGR03173
699034006972	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034006973	Walker A motif; other site
699034006974	ATP binding site [chemical binding]; other site
699034006975	Walker B motif; other site
699034006976	arginine finger; other site
699034006977	McrBC 5-methylcytosine restriction system component; Region: McrBC; pfam10117
699034006978	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl18944
699034006979	Tubulin/FtsZ: Family includes tubulin alpha-, beta-, gamma-, delta-, and epsilon-tubulins as well as FtsZ, all of which are involved in polymer formation. Tubulin is the major component of microtubules, but also exists as a heterodimer and as a curved...; Region: Tubulin_FtsZ; cl10017
699034006980	Predicted transcriptional regulator [Transcription]; Region: COG2378
699034006981	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
699034006982	putative DNA binding site [nucleotide binding]; other site
699034006983	putative Zn2+ binding site [ion binding]; other site
699034006984	WYL domain; Region: WYL; pfam13280
699034006985	QueT transporter; Region: QueT; pfam06177
699034006986	xanthine dehydrogenase subunit XdhA; Provisional; Region: PRK09970
699034006987	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
699034006988	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
699034006989	Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion]; Region: CoxS; COG2080
699034006990	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
699034006991	catalytic loop [active]
699034006992	iron binding site [ion binding]; other site
699034006993	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
699034006994	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion]; Region: CoxM; COG1319
699034006995	FAD binding domain; Region: FAD_binding_4; cl19922
699034006996	CO dehydrogenase flavoprotein C-terminal domain; Region: CO_deh_flav_C; pfam03450
699034006997	NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism]; Region: NhaP; COG0025
699034006998	Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism]; Region: KefB; cl10482
699034006999	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
699034007000	ABC-type Na+ transport system, ATPase component [Energy production and conversion / Inorganic ion transport and metabolism]; Region: NatA; COG4555
699034007001	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
699034007002	Walker A/P-loop; other site
699034007003	ATP binding site [chemical binding]; other site
699034007004	Q-loop/lid; other site
699034007005	ABC transporter signature motif; other site
699034007006	Walker B; other site
699034007007	D-loop; other site
699034007008	H-loop/switch region; other site
699034007009	helicase 45; Provisional; Region: PTZ00424
699034007010	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
699034007011	ATP binding site [chemical binding]; other site
699034007012	putative Mg++ binding site [ion binding]; other site
699034007013	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
699034007014	nucleotide binding region [chemical binding]; other site
699034007015	ATP-binding site [chemical binding]; other site
699034007016	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
699034007017	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
699034007018	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Bacillus subtilis yoeA; Region: MATE_yoeA_like; cd13138
699034007019	anion transporter; Region: dass; TIGR00785
699034007020	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
699034007021	transmembrane helices; other site
699034007022	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
699034007023	active site
699034007024	intersubunit interactions; other site
699034007025	catalytic residue [active]
699034007026	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
699034007027	DeoR-like helix-turn-helix domain; Region: HTH_DeoR; cl17531
699034007028	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
699034007029	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034007030	dimer interface [polypeptide binding]; other site
699034007031	phosphorylation site [posttranslational modification]
699034007032	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034007033	ATP binding site [chemical binding]; other site
699034007034	G-X-G motif; other site
699034007035	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034007036	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034007037	active site
699034007038	phosphorylation site [posttranslational modification]
699034007039	intermolecular recognition site; other site
699034007040	dimerization interface [polypeptide binding]; other site
699034007041	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034007042	DNA binding site [nucleotide binding]
699034007043	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
699034007044	metal-binding site [ion binding]
699034007045	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: ZntA; COG2217
699034007046	Heavy-metal-associated domain (HMA) is a conserved domain of approximately 30 amino acid residues found in a number of proteins that transport or detoxify heavy metals, for example, the CPx-type heavy metal ATPases and copper chaperones. HMA domain...; Region: HMA; cd00371
699034007047	metal-binding site [ion binding]
699034007048	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
699034007049	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
699034007050	motif II; other site
699034007051	Predicted membrane GTPase involved in stress response [Signal transduction mechanisms]; Region: TypA; COG1217
699034007052	Tyrosine phosphorylated protein A (TypA)/BipA family belongs to ribosome-binding GTPases; Region: TypA_BipA; cd01891
699034007053	G1 box; other site
699034007054	putative GEF interaction site [polypeptide binding]; other site
699034007055	GTP/Mg2+ binding site [chemical binding]; other site
699034007056	Switch I region; other site
699034007057	G2 box; other site
699034007058	G3 box; other site
699034007059	Switch II region; other site
699034007060	G4 box; other site
699034007061	G5 box; other site
699034007062	BipA_TypA_II: domain II of BipA (also called TypA) having homology to domain II of the elongation factors (EFs) EF-G and EF-Tu.  BipA is a highly conserved protein with global regulatory properties in Escherichia coli. BipA is phosphorylated on a...; Region: BipA_TypA_II; cd03691
699034007063	BipA_TypA_C: a C-terminal portion of BipA or TypA having homology to the C terminal domains of the elongation factors EF-G and EF-2. A member of the ribosome binding GTPase superfamily, BipA is widely distributed in bacteria and plants.  BipA is a highly...; Region: BipA_TypA_C; cd03710
699034007064	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
699034007065	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
699034007066	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
699034007067	threonine synthase; Validated; Region: PRK09225
699034007068	Threonine synthase catalyzes the final step of threonine biosynthesis. The conversion of O-phosphohomoserine into threonine and inorganic phosphate is pyridoxal 5'-phosphate dependent. The Thr-synth_1 CD includes members from higher plants; Region: Thr-synth_2; cd01560
699034007069	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034007070	catalytic residue [active]
699034007071	homoserine kinase; Provisional; Region: PRK01212
699034007072	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
699034007073	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
699034007074	Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only]; Region: COG2070
699034007075	2-Nitropropane dioxygenase (NPD), one of the nitroalkane oxidizing enzyme families, catalyzes oxidative denitrification of nitroalkanes to their corresponding carbonyl compounds and nitrites. NDP is a member of the NAD(P)H-dependent flavin oxidoreductase...; Region: NPD_like; cd04730
699034007076	FMN binding site [chemical binding]; other site
699034007077	substrate binding site [chemical binding]; other site
699034007078	putative catalytic residue [active]
699034007079	Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family [General function prediction only]; Region: COG1853
699034007080	CorA-like Mg2+ transporter protein; Region: CorA; pfam01544
699034007081	uncharacterized bacterial subfamily of the Escherichia coli CorA-Salmonella typhimurium ZntB family; Region: EcCorA_ZntB-like_u2; cd12827
699034007082	Cl binding site [ion binding]; other site
699034007083	oligomer interface [polypeptide binding]; other site
699034007084	FOG: TPR repeat, SEL1 subfamily [General function prediction only]; Region: COG0790
699034007085	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
699034007086	binding surface
699034007087	TPR motif; other site
699034007088	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
699034007089	binding surface
699034007090	TPR motif; other site
699034007091	FOG: TPR repeat [General function prediction only]; Region: NrfG; COG0457
699034007092	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
699034007093	binding surface
699034007094	TPR motif; other site
699034007095	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
699034007096	binding surface
699034007097	TPR motif; other site
699034007098	Predicted permeases [General function prediction only]; Region: COG0679
699034007099	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
699034007100	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
699034007101	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cl17182
699034007102	Coenzyme A binding pocket [chemical binding]; other site
699034007103	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Reviewed; Region: ispG; PRK00366
699034007104	1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase; Region: ispG_gcpE; TIGR00612
699034007105	RIP metalloprotease RseP; Region: TIGR00054
699034007106	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
699034007107	active site
699034007108	PDZ domain of bacterial and plant zinc metalloprotases, presumably membrane-associated or integral membrane proteases, which may be involved in signalling and regulatory mechanisms. May be responsible for substrate recognition and/or binding, as most PDZ...; Region: PDZ_metalloprotease; cd00989
699034007109	protein binding site [polypeptide binding]; other site
699034007110	putative substrate binding region [chemical binding]; other site
699034007111	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Provisional; Region: PRK05447
699034007112	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
699034007113	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
699034007114	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
699034007115	Cro/C1-type HTH DNA-binding domain; Region: HTH_26; pfam13443
699034007116	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
699034007117	metal binding site [ion binding]; metal-binding site
699034007118	active site
699034007119	I-site; other site
699034007120	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
699034007121	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
699034007122	Cis (Z)-Isoprenyl Diphosphate Synthases; Region: Cis_IPPS; cd00475
699034007123	active site
699034007124	dimer interface [polypeptide binding]; other site
699034007125	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
699034007126	hinge region; other site
699034007127	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
699034007128	putative nucleotide binding site [chemical binding]; other site
699034007129	uridine monophosphate binding site [chemical binding]; other site
699034007130	homohexameric interface [polypeptide binding]; other site
699034007131	elongation factor Ts; Provisional; Region: tsf; PRK09377
699034007132	UBA/TS-N domain; Region: UBA; pfam00627
699034007133	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
699034007134	rRNA interaction site [nucleotide binding]; other site
699034007135	S8 interaction site; other site
699034007136	putative laminin-1 binding site; other site
699034007137	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
699034007138	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl19191
699034007139	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
699034007140	Pentapeptide repeats (9 copies); Region: Pentapeptide_3; pfam13576
699034007141	Ion channel; Region: Ion_trans_2; pfam07885
699034007142	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
699034007143	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034007144	non-specific DNA binding site [nucleotide binding]; other site
699034007145	salt bridge; other site
699034007146	sequence-specific DNA binding site [nucleotide binding]; other site
699034007147	Protein of unknown function (DUF1232); Region: DUF1232; pfam06803
699034007148	putative sporulation protein YtaF; Region: spore_YtaF; TIGR02840
699034007149	Domain of unknown function DUF; Region: DUF204; pfam02659
699034007150	DNA-binding domain of DNA mismatch repair MUTS family; Region: MUTSd; smart00533
699034007151	MutS domain III; Region: MutS_III; pfam05192
699034007152	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034007153	Walker A/P-loop; other site
699034007154	ATP binding site [chemical binding]; other site
699034007155	Q-loop/lid; other site
699034007156	ABC transporter signature motif; other site
699034007157	Walker B; other site
699034007158	D-loop; other site
699034007159	H-loop/switch region; other site
699034007160	hypothetical protein; Reviewed; Region: PRK09588
699034007161	tRNA-splicing ligase RtcB; Region: RtcB; pfam01139
699034007162	Catalytic domain of Protein Kinases; Region: PKc; cd00180
699034007163	active site
699034007164	ATP binding site [chemical binding]; other site
699034007165	substrate binding site [chemical binding]; other site
699034007166	activation loop (A-loop); other site
699034007167	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
699034007168	VanW like protein; Region: VanW; pfam04294
699034007169	Exonuclease-Endonuclease-Phosphatase (EEP) domain superfamily; Region: EEP; cl00490
699034007170	putative catalytic site [active]
699034007171	putative metal binding site [ion binding]; other site
699034007172	putative phosphate binding site [ion binding]; other site
699034007173	Protein of unknown function (DUF819); Region: DUF819; cl02317
699034007174	M42 Peptidase, Endoglucanase-like subfamily; Region: M42_glucanase_like; cd05657
699034007175	Cellulase M and related proteins [Carbohydrate transport and metabolism]; Region: FrvX; COG1363
699034007176	putative oligomer interface [polypeptide binding]; other site
699034007177	putative active site [active]
699034007178	metal binding site [ion binding]; metal-binding site
699034007179	putative iron-only hydrogenase system regulator; Region: hyd_TM1266; TIGR03959
699034007180	[FeFe] hydrogenase H-cluster maturation GTPase HydF; Region: GTP_HydF; TIGR03918
699034007181	E. coli Ras-like protein (Era)-like GTPase; Region: Era_like; cd00880
699034007182	G1 box; other site
699034007183	GTP/Mg2+ binding site [chemical binding]; other site
699034007184	Switch I region; other site
699034007185	G2 box; other site
699034007186	Switch II region; other site
699034007187	G3 box; other site
699034007188	G4 box; other site
699034007189	G5 box; other site
699034007190	[FeFe] hydrogenase H-cluster radical SAM maturase HydE; Region: rSAM_HydE; TIGR03956
699034007191	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
699034007192	FeS/SAM binding site; other site
699034007193	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
699034007194	thiamine biosynthesis protein ThiH; Reviewed; Region: thiH; PRK09613
699034007195	Biotin and Thiamin Synthesis associated domain; Region: BATS; smart00876
699034007196	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
699034007197	Adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]; Region: BioA; COG0161
699034007198	inhibitor-cofactor binding pocket; inhibition site
699034007199	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034007200	catalytic residue [active]
699034007201	Protein of unknown function (DUF1113); Region: DUF1113; pfam06541
699034007202	VanZ like family; Region: VanZ; pfam04892
699034007203	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
699034007204	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
699034007205	Coenzyme A binding pocket [chemical binding]; other site
699034007206	Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain [General function prediction only]; Region: COG2872
699034007207	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
699034007208	DHHA1 domain; Region: DHHA1; pfam02272
699034007209	L-2-hydroxyisocapronate dehydrogenases and some bacterial L-lactate dehydrogenases; Region: HicDH_like; cd05291
699034007210	tetramer (dimer of dimers) interface [polypeptide binding]; other site
699034007211	L-lactate dehydrogenase; Region: L-LDH-NAD; TIGR01771
699034007212	NAD binding site [chemical binding]; other site
699034007213	dimer interface [polypeptide binding]; other site
699034007214	substrate binding site [chemical binding]; other site
699034007215	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034007216	non-specific DNA binding site [nucleotide binding]; other site
699034007217	salt bridge; other site
699034007218	sequence-specific DNA binding site [nucleotide binding]; other site
699034007219	Domain of unknown function (DUF955); Region: DUF955; cl01076
699034007220	methionine sulfoxide reductase A; Provisional; Region: PRK14054
699034007221	methionine sulfoxide reductase B; Provisional; Region: PRK00222
699034007222	Patatins and Phospholipases; Region: Patatin_and_cPLA2; cl11396
699034007223	active site
699034007224	nucleophile elbow; other site
699034007225	Hybrid cluster protein (HCP), formerly known as prismane, is thought to play a role in nitrogen metabolism but its specific function is unknown. HCP has three structural domains, an N-terminal alpha-helical domain, and two similar domains comprising a...; Region: HCP; cd01914
699034007226	cubane metal cluster [ion binding]; other site
699034007227	hybrid metal cluster; other site
699034007228	Ferredoxin [Energy production and conversion]; Region: COG1146
699034007229	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
699034007230	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
699034007231	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
699034007232	ligand binding site [chemical binding]; other site
699034007233	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
699034007234	non-specific DNA interactions [nucleotide binding]; other site
699034007235	DNA binding site [nucleotide binding]
699034007236	sequence specific DNA binding site [nucleotide binding]; other site
699034007237	putative cAMP binding site [chemical binding]; other site
699034007238	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
699034007239	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
699034007240	ATP-binding cassette domain of the histidine and glutamine transporters; Region: ABC_HisP_GlnQ; cd03262
699034007241	Walker A/P-loop; other site
699034007242	ATP binding site [chemical binding]; other site
699034007243	Q-loop/lid; other site
699034007244	ABC transporter signature motif; other site
699034007245	Walker B; other site
699034007246	D-loop; other site
699034007247	H-loop/switch region; other site
699034007248	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
699034007249	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
699034007250	metal binding site [ion binding]; metal-binding site
699034007251	dimer interface [polypeptide binding]; other site
699034007252	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
699034007253	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
699034007254	substrate binding pocket [chemical binding]; other site
699034007255	membrane-bound complex binding site; other site
699034007256	hinge residues; other site
699034007257	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: HisM; COG0765
699034007258	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034007259	dimer interface [polypeptide binding]; other site
699034007260	conserved gate region; other site
699034007261	putative PBP binding loops; other site
699034007262	ABC-ATPase subunit interface; other site
699034007263	ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; Region: HisM; COG0765
699034007264	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034007265	dimer interface [polypeptide binding]; other site
699034007266	conserved gate region; other site
699034007267	putative PBP binding loops; other site
699034007268	ABC-ATPase subunit interface; other site
699034007269	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
699034007270	Bacterial extracellular solute-binding proteins, family 3; Region: SBP_bac_3; pfam00497
699034007271	substrate binding pocket [chemical binding]; other site
699034007272	membrane-bound complex binding site; other site
699034007273	hinge residues; other site
699034007274	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
699034007275	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
699034007276	Anaerobic dehydrogenases, typically selenocysteine-containing [Energy production and conversion]; Region: BisC; COG0243
699034007277	Molybdopterin-Binding (MopB) domain of the MopB superfamily of proteins, a  large, diverse, heterogeneous superfamily of enzymes that, in general, bind molybdopterin as a cofactor. The MopB domain is found in a wide variety of molybdenum- and...; Region: Molybdopterin-Binding; cl09928
699034007278	molybdopterin cofactor binding site; other site
699034007279	Molydopterin dinucleotide binding domain; Region: Molydop_binding; pfam01568
699034007280	Bacterial SNF2 helicase associated; Region: SNF2_assoc; pfam08455
699034007281	SNF2 family N-terminal domain; Region: SNF2_N; pfam00176
699034007282	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
699034007283	ATP binding site [chemical binding]; other site
699034007284	putative Mg++ binding site [ion binding]; other site
699034007285	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
699034007286	nucleotide binding region [chemical binding]; other site
699034007287	ATP-binding site [chemical binding]; other site
699034007288	Putative lysophospholipase; Region: Hydrolase_4; cl19140
699034007289	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
699034007290	Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis]; Region: SrmB; COG0513
699034007291	DEAD-box helicases. A diverse family of proteins involved in ATP-dependent RNA unwinding, needed in a variety of cellular processes including splicing, ribosome biogenesis and RNA degradation. The name derives from the sequence of the Walker  B motif; Region: DEADc; cd00268
699034007292	ATP binding site [chemical binding]; other site
699034007293	Mg++ binding site [ion binding]; other site
699034007294	motif III; other site
699034007295	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
699034007296	nucleotide binding region [chemical binding]; other site
699034007297	ATP-binding site [chemical binding]; other site
699034007298	RNA recognition motif in Bacillus subtilis ATP-dependent RNA helicase YxiN and similar proteins; Region: RRM_BsYxiN_like; cd12500
699034007299	RNA binding site [nucleotide binding]; other site
699034007300	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
699034007301	active site
699034007302	metal binding site [ion binding]; metal-binding site
699034007303	Domain of unknown function DUF11; Region: DUF11; cl17728
699034007304	Domain of unknown function (DUF3794); Region: DUF3794; pfam12673
699034007305	Glycosyl hydrolases related to GH101 family, GHL1-GHL3; Region: GHL1-3; pfam11308
699034007306	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; cl17361
699034007307	maltose phosphorylase; Provisional; Region: PRK13807
699034007308	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
699034007309	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
699034007310	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
699034007311	beta-phosphoglucomutase; Region: bPGM; TIGR01990
699034007312	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
699034007313	N-terminal Early set domain associated with the catalytic domain of cyclomaltodextrinase and pullulan-degrading enzymes; Region: E_set_CDase_PDE_N; cd02857
699034007314	homodimer interface [polypeptide binding]; other site
699034007315	Alpha amylase catalytic domain found in cyclomaltodextrinases and related proteins; Region: AmyAc_CMD; cd11338
699034007316	Alpha amylase, catalytic domain; Region: Alpha-amylase; pfam00128
699034007317	active site
699034007318	homodimer interface [polypeptide binding]; other site
699034007319	catalytic site [active]
699034007320	histidinol-phosphatase; Provisional; Region: PRK05588
699034007321	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
699034007322	active site
699034007323	ferrous iron transport protein B; Reviewed; Region: feoB; PRK09554
699034007324	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034007325	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034007326	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034007327	Mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase; Region: Glucosaminidase; cl17361
699034007328	helix_turn_helix, cAMP Regulatory protein C-terminus; DNA binding domain of prokaryotic regulatory proteins belonging to the catabolite activator protein family; Region: HTH_CRP; cl17320
699034007329	non-specific DNA interactions [nucleotide binding]; other site
699034007330	DNA binding site [nucleotide binding]
699034007331	sequence specific DNA binding site [nucleotide binding]; other site
699034007332	putative cAMP binding site [chemical binding]; other site
699034007333	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
699034007334	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
699034007335	nucleotide binding site [chemical binding]; other site
699034007336	nonheme-containing ferritins; Region: Nonheme_Ferritin; cd01055
699034007337	Ferritin-like domain; Region: Ferritin; pfam00210
699034007338	ferroxidase diiron center [ion binding]; other site
699034007339	Acyl-CoA synthetase (NDP forming) [Energy production and conversion]; Region: COG1042
699034007340	CoA binding domain; Region: CoA_binding_2; pfam13380
699034007341	Succinyl-CoA ligase like flavodoxin domain; Region: Succ_CoA_lig; pfam13607
699034007342	ATP-grasp domain; Region: ATP-grasp_5; pfam13549
699034007343	Pyruvate ferredoxin/flavodoxin oxidoreductase; Region: POR; pfam01558
699034007344	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit [Energy production and conversion]; Region: PorB; COG1013
699034007345	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
699034007346	TPP-binding site [chemical binding]; other site
699034007347	2-ketoisovalerate ferredoxin reductase; Validated; Region: PRK07119
699034007348	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
699034007349	dimer interface [polypeptide binding]; other site
699034007350	PYR/PP interface [polypeptide binding]; other site
699034007351	TPP binding site [chemical binding]; other site
699034007352	substrate binding site [chemical binding]; other site
699034007353	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
699034007354	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
699034007355	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
699034007356	histidinol-phosphate aminotransferase; Validated; Region: PRK02731
699034007357	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
699034007358	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034007359	homodimer interface [polypeptide binding]; other site
699034007360	catalytic residue [active]
699034007361	melibiose:sodium symporter; Provisional; Region: PRK10429; cl15392
699034007362	MFS/sugar transport protein; Region: MFS_2; pfam13347
699034007363	Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain; Region: SLC5sbd; cd10322
699034007364	Na binding site [ion binding]; other site
699034007365	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
699034007366	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
699034007367	Putative esterase; Region: Esterase; pfam00756
699034007368	Predicted hydrolase of the alpha/beta superfamily [General function prediction only]; Region: COG2819; cl19187
699034007369	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
699034007370	Domain of unknown function DUF20; Region: UPF0118; pfam01594
699034007371	Bacillus subtilis aldehyde dehydrogenase ywdH-like; Region: ALDH_YwdH-P39616; cd07136
699034007372	NAD(P) binding site [chemical binding]; other site
699034007373	catalytic residues [active]
699034007374	Flavodoxin domain; Region: Flavodoxin_5; pfam12724
699034007375	Transcriptional regulators [Transcription]; Region: MarR; COG1846
699034007376	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
699034007377	GTP-binding protein HflX; Region: GTP_HflX; TIGR03156
699034007378	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
699034007379	HflX GTPase family; Region: HflX; cd01878
699034007380	G1 box; other site
699034007381	GTP/Mg2+ binding site [chemical binding]; other site
699034007382	Switch I region; other site
699034007383	G2 box; other site
699034007384	G3 box; other site
699034007385	Switch II region; other site
699034007386	G4 box; other site
699034007387	G5 box; other site
699034007388	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
699034007389	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
699034007390	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
699034007391	Walker A/P-loop; other site
699034007392	ATP binding site [chemical binding]; other site
699034007393	Q-loop/lid; other site
699034007394	ABC transporter signature motif; other site
699034007395	Walker B; other site
699034007396	D-loop; other site
699034007397	H-loop/switch region; other site
699034007398	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
699034007399	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
699034007400	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034007401	Walker A/P-loop; other site
699034007402	ATP binding site [chemical binding]; other site
699034007403	Q-loop/lid; other site
699034007404	ABC transporter signature motif; other site
699034007405	Walker B; other site
699034007406	D-loop; other site
699034007407	H-loop/switch region; other site
699034007408	Transcriptional regulators [Transcription]; Region: MarR; COG1846
699034007409	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
699034007410	putative DNA binding site [nucleotide binding]; other site
699034007411	putative Zn2+ binding site [ion binding]; other site
699034007412	Carbonic anhydrases (CA) are zinc-containing enzymes that catalyze the reversible hydration of carbon dioxide in a two-step mechanism in which the nucleophilic attack of a zinc-bound hydroxide ion on carbon dioxide is followed by the regeneration of an...; Region: beta_CA_cladeD; cd03379
699034007413	active site clefts [active]
699034007414	zinc binding site [ion binding]; other site
699034007415	dimer interface [polypeptide binding]; other site
699034007416	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034007417	non-specific DNA binding site [nucleotide binding]; other site
699034007418	salt bridge; other site
699034007419	sequence-specific DNA binding site [nucleotide binding]; other site
699034007420	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034007421	non-specific DNA binding site [nucleotide binding]; other site
699034007422	salt bridge; other site
699034007423	sequence-specific DNA binding site [nucleotide binding]; other site
699034007424	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
699034007425	active site
699034007426	catalytic residue [active]
699034007427	dimer interface [polypeptide binding]; other site
699034007428	Acetyltransferase (isoleucine patch superfamily) [General function prediction only]; Region: WbbJ; COG0110
699034007429	Xenobiotic acyltransferase (XAT): The XAT class of hexapeptide acyltransferases is composed of a large number of microbial enzymes that catalyze the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and...; Region: LbH_XAT; cd03349
699034007430	trimer interface [polypeptide binding]; other site
699034007431	active site
699034007432	substrate binding site [chemical binding]; other site
699034007433	CoA binding site [chemical binding]; other site
699034007434	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
699034007435	Radical SAM superfamily; Region: Radical_SAM; pfam04055
699034007436	FeS/SAM binding site; other site
699034007437	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
699034007438	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
699034007439	Formate/nitrite transporter; Region: Form_Nir_trans; pfam01226
699034007440	sulfite reductase, subunit C; Region: sulfite_red_C; TIGR02912
699034007441	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
699034007442	Nitrite and sulphite reductase 4Fe-4S domain; Region: NIR_SIR; pfam01077
699034007443	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
699034007444	4Fe-4S binding domain; Region: Fer4; pfam00037
699034007445	anaerobic sulfite reductase subunit B; Provisional; Region: PRK08221
699034007446	Anaerobic sulfite reductase contains an FAD and NADPH binding module with structural similarity to ferredoxin reductase and sequence similarity to dihydroorotate dehydrogenases. Clostridium pasteurianum inducible dissimilatory type sulfite reductase is...; Region: sulfite_reductase_like; cd06221
699034007447	FAD binding pocket [chemical binding]; other site
699034007448	FAD binding motif [chemical binding]; other site
699034007449	phosphate binding motif [ion binding]; other site
699034007450	beta-alpha-beta structure motif; other site
699034007451	NAD binding pocket [chemical binding]; other site
699034007452	Iron coordination center [ion binding]; other site
699034007453	anaerobic sulfite reductase subunit A; Provisional; Region: PRK15055
699034007454	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
699034007455	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
699034007456	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
699034007457	ligand binding site [chemical binding]; other site
699034007458	flexible hinge region; other site
699034007459	Crp-like helix-turn-helix domain; Region: HTH_Crp_2; pfam13545
699034007460	putative switch regulator; other site
699034007461	non-specific DNA interactions [nucleotide binding]; other site
699034007462	DNA binding site [nucleotide binding]
699034007463	sequence specific DNA binding site [nucleotide binding]; other site
699034007464	putative cAMP binding site [chemical binding]; other site
699034007465	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
699034007466	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
699034007467	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
699034007468	putative active site [active]
699034007469	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
699034007470	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
699034007471	nucleotide binding site [chemical binding]; other site
699034007472	Domain of unknown function (DUF303); Region: DUF303; pfam03629
699034007473	Domain of unknown function (DUF386); Region: DUF386; cl01047
699034007474	uncharacterized subgroup of the Na(+)/iodide (NIS) cotransporter subfamily; putative solute-binding domain; Region: SLC5sbd_NIS-like_u3; cd11495
699034007475	Na binding site [ion binding]; other site
699034007476	N-acetylneuraminate lyase; Provisional; Region: PRK04147
699034007477	N-Acetylneuraminic acid aldolase, also called N-acetylneuraminate lyase (NAL); Region: NAL; cd00954
699034007478	inhibitor site; inhibition site
699034007479	active site
699034007480	dimer interface [polypeptide binding]; other site
699034007481	catalytic residue [active]
699034007482	N-acetylmannosamine-6-phosphate epimerase (NanE) converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate. This reaction is part of the pathway that allows the usage of sialic acid as a carbohydrate source. Sialic acids are a family of...; Region: NanE; cd04729
699034007483	N-acetylmannosamine-6-phosphate 2-epimerase; Provisional; Region: PRK01130
699034007484	putative active site cavity [active]
699034007485	Double zinc ribbon; Region: DZR; pfam12773
699034007486	zinc-ribbon domain; Region: zf-ribbon_3; pfam13248
699034007487	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
699034007488	metal binding site [ion binding]; metal-binding site
699034007489	active site
699034007490	I-site; other site
699034007491	asparaginyl-tRNA synthetase; Validated; Region: asnC; PRK03932
699034007492	EcAsnRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli asparaginyl-tRNA synthetase (AsnRS) and, in Arabidopsis thaliana and Saccharomyces cerevisiae mitochondrial (mt) AsnRS. This domain is a beta-barrel domain (OB...; Region: EcAsnRS_like_N; cd04318
699034007493	putative dimer interface [polypeptide binding]; other site
699034007494	putative anticodon binding site; other site
699034007495	Asx tRNA synthetase (AspRS/AsnRS) class II core domain.  Assignment to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs in the core domain. This family includes AsnRS as well as...; Region: AsxRS_core; cd00776
699034007496	homodimer interface [polypeptide binding]; other site
699034007497	motif 1; other site
699034007498	motif 2; other site
699034007499	active site
699034007500	motif 3; other site
699034007501	Domain of unknown function (DUF3787); Region: DUF3787; pfam12655
699034007502	Peptidase S8 family domain in CspA-like proteins; Region: Peptidases_S8_CspA-like; cd07478
699034007503	active site
699034007504	catalytic triad [active]
699034007505	Peptidase S8 family domain in CspA-like proteins; Region: Peptidases_S8_CspA-like; cd07478
699034007506	active site
699034007507	catalytic triad [active]
699034007508	Peptidase S8 family domain in CspA-like proteins; Region: Peptidases_S8_CspA-like; cd07478
699034007509	active site
699034007510	catalytic triad [active]
699034007511	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3825
699034007512	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
699034007513	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034007514	Walker A motif; other site
699034007515	ATP binding site [chemical binding]; other site
699034007516	Walker B motif; other site
699034007517	arginine finger; other site
699034007518	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
699034007519	Domain of unknown function DUF20; Region: UPF0118; pfam01594
699034007520	Lysine 2,3-aminomutase [Amino acid transport and metabolism]; Region: KamA; COG1509
699034007521	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
699034007522	FeS/SAM binding site; other site
699034007523	Lysine-2,3-aminomutase; Region: LAM_C; pfam12544
699034007524	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
699034007525	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
699034007526	DNA-binding site [nucleotide binding]; DNA binding site
699034007527	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
699034007528	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034007529	homodimer interface [polypeptide binding]; other site
699034007530	catalytic residue [active]
699034007531	Aspartate racemase [Cell envelope biogenesis, outer membrane]; Region: RacX; COG1794
699034007532	Phosphotransferase system, EIIC; Region: PTS_EIIC_2; pfam13303
699034007533	Cupin domain; Region: Cupin_2; pfam07883
699034007534	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
699034007535	Major Facilitator Superfamily; Region: MFS_1; pfam07690
699034007536	putative substrate translocation pore; other site
699034007537	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
699034007538	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
699034007539	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
699034007540	X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP; cd01085
699034007541	active site
699034007542	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
699034007543	Major Facilitator Superfamily; Region: MFS_1; pfam07690
699034007544	putative substrate translocation pore; other site
699034007545	POT family; Region: PTR2; cl17359
699034007546	SurA N-terminal domain; Region: SurA_N_3; cl07813
699034007547	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
699034007548	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
699034007549	FAD dependent oxidoreductase; Region: DAO; pfam01266
699034007550	Rieske Fe-S protein [Energy production and conversion]; Region: QcrA; COG0723
699034007551	YhfW family, C-terminal Rieske domain; YhfW is a protein of unknown function with an N-terminal DadA-like (glycine/D-amino acid dehydrogenase) domain and a C-terminal Rieske domain. The Rieske domain is a [2Fe-2S] cluster binding domain involved in...; Region: Rieske_YhfW_C; cd03477
699034007552	[2Fe-2S] cluster binding site [ion binding]; other site
699034007553	CAAX protease self-immunity; Region: Abi; pfam02517
699034007554	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
699034007555	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
699034007556	active site
699034007557	phosphorylation site [posttranslational modification]
699034007558	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
699034007559	active site
699034007560	P-loop; other site
699034007561	phosphorylation site [posttranslational modification]
699034007562	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
699034007563	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
699034007564	putative substrate binding site [chemical binding]; other site
699034007565	putative ATP binding site [chemical binding]; other site
699034007566	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
699034007567	HTH domain; Region: HTH_11; pfam08279
699034007568	Mga helix-turn-helix domain; Region: Mga; pfam05043
699034007569	PRD domain; Region: PRD; pfam00874
699034007570	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
699034007571	active site
699034007572	P-loop; other site
699034007573	phosphorylation site [posttranslational modification]
699034007574	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
699034007575	active site
699034007576	phosphorylation site [posttranslational modification]
699034007577	Protein tyrosine/serine phosphatase [Signal transduction mechanisms]; Region: COG2365
699034007578	Tyrosine phosphatase family; Region: Y_phosphatase3; pfam13350
699034007579	Tyrosine phosphatase family C-terminal region; Region: Y_phosphatase3C; pfam13348
699034007580	Domain of unknown function DUF20; Region: UPF0118; cl00465
699034007581	DNA topoisomerase III; Provisional; Region: PRK07726
699034007582	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
699034007583	active site
699034007584	putative interdomain interaction site [polypeptide binding]; other site
699034007585	putative metal-binding site [ion binding]; other site
699034007586	putative nucleotide binding site [chemical binding]; other site
699034007587	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
699034007588	domain I; other site
699034007589	DNA binding groove [nucleotide binding]
699034007590	phosphate binding site [ion binding]; other site
699034007591	domain II; other site
699034007592	domain III; other site
699034007593	nucleotide binding site [chemical binding]; other site
699034007594	catalytic site [active]
699034007595	domain IV; other site
699034007596	Zn-finger domain associated with topoisomerase type I [DNA replication, recombination, and repair]; Region: TopA; COG0551
699034007597	RNA polymerases M/15 Kd subunit; Region: RNA_POL_M_15KD; cl02717
699034007598	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
699034007599	Class II Aldolase and Adducin N-terminal domain; Region: Aldolase_II; pfam00596
699034007600	intersubunit interface [polypeptide binding]; other site
699034007601	active site
699034007602	Zn2+ binding site [ion binding]; other site
699034007603	Class II Aldolase and Adducin head (N-terminal) domain. Aldolases are ubiquitous enzymes catalyzing central steps of carbohydrate metabolism. Based on enzymatic mechanisms, this superfamily has been divided into two distinct classes (Class I and II); Region: Aldolase_II; cd00398
699034007604	intersubunit interface [polypeptide binding]; other site
699034007605	active site
699034007606	Zn2+ binding site [ion binding]; other site
699034007607	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
699034007608	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
699034007609	putative NAD(P) binding site [chemical binding]; other site
699034007610	catalytic Zn binding site [ion binding]; other site
699034007611	PTS system sugar-specific permease component; Region: EIIC-GAT; cl04451
699034007612	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
699034007613	active site
699034007614	P-loop; other site
699034007615	phosphorylation site [posttranslational modification]
699034007616	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
699034007617	active site
699034007618	phosphorylation site [posttranslational modification]
699034007619	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
699034007620	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034007621	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
699034007622	Walker A motif; other site
699034007623	ATP binding site [chemical binding]; other site
699034007624	Walker B motif; other site
699034007625	arginine finger; other site
699034007626	PRD domain; Region: PRD; pfam00874
699034007627	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
699034007628	active pocket/dimerization site; other site
699034007629	active site
699034007630	phosphorylation site [posttranslational modification]
699034007631	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; Region: PTS_EIIA_2; pfam00359
699034007632	active site
699034007633	phosphorylation site [posttranslational modification]
699034007634	Domain of unknown function (DUF3284); Region: DUF3284; pfam11687
699034007635	Penicillinase repressor; Region: Penicillinase_R; cl17580
699034007636	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
699034007637	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
699034007638	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
699034007639	DNA-binding site [nucleotide binding]; DNA binding site
699034007640	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
699034007641	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034007642	homodimer interface [polypeptide binding]; other site
699034007643	catalytic residue [active]
699034007644	AzlC protein; Region: AzlC; pfam03591
699034007645	Branched-chain amino acid transport protein (AzlD); Region: AzlD; pfam05437
699034007646	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034007647	HAMP domain; Region: HAMP; pfam00672
699034007648	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034007649	dimer interface [polypeptide binding]; other site
699034007650	phosphorylation site [posttranslational modification]
699034007651	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034007652	ATP binding site [chemical binding]; other site
699034007653	Mg2+ binding site [ion binding]; other site
699034007654	G-X-G motif; other site
699034007655	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034007656	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034007657	active site
699034007658	phosphorylation site [posttranslational modification]
699034007659	intermolecular recognition site; other site
699034007660	dimerization interface [polypeptide binding]; other site
699034007661	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034007662	DNA binding site [nucleotide binding]
699034007663	Penicillinase repressor; Region: Penicillinase_R; cl17580
699034007664	Penicillinase repressor; Region: Penicillinase_R; cl17580
699034007665	type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710
699034007666	Type II secretion system (T2SS), protein G; Region: T2SG; pfam08334
699034007667	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
699034007668	Protein of unknown function (DUF3796); Region: DUF3796; pfam12676
699034007669	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034007670	non-specific DNA binding site [nucleotide binding]; other site
699034007671	salt bridge; other site
699034007672	sequence-specific DNA binding site [nucleotide binding]; other site
699034007673	putative transposase OrfB; Reviewed; Region: PHA02517
699034007674	HTH-like domain; Region: HTH_21; pfam13276
699034007675	Integrase core domain; Region: rve; pfam00665
699034007676	Integrase core domain; Region: rve_2; pfam13333
699034007677	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
699034007678	Helix-turn-helix domain; Region: HTH_28; pfam13518
699034007679	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
699034007680	Transposase; Region: HTH_Tnp_1; cl17663
699034007681	Helix-turn-helix domain; Region: HTH_28; pfam13518
699034007682	Cold-Shock Protein (CSP) contains an S1-like cold-shock domain (CSD) that is found in eukaryotes, prokaryotes, and archaea.  CSP's include the major cold-shock proteins CspA and CspB in bacteria and the eukaryotic gene regulatory factor Y-box...; Region: CSP_CDS; cd04458
699034007683	DNA-binding site [nucleotide binding]; DNA binding site
699034007684	RNA-binding motif; other site
699034007685	ABC-type amino acid transport/signal transduction systems, periplasmic component/domain [Amino acid transport and metabolism / Signal transduction mechanisms]; Region: HisJ; COG0834
699034007686	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
699034007687	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
699034007688	substrate binding pocket [chemical binding]; other site
699034007689	membrane-bound complex binding site; other site
699034007690	hinge residues; other site
699034007691	ABC-type sulfate transport system, permease component [Posttranslational modification, protein turnover, chaperones]; Region: CysU; COG0555
699034007692	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034007693	dimer interface [polypeptide binding]; other site
699034007694	conserved gate region; other site
699034007695	putative PBP binding loops; other site
699034007696	ABC-ATPase subunit interface; other site
699034007697	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034007698	sulfate ABC transporter, ATP-binding protein; Region: 3a0106s01; TIGR00968
699034007699	Walker A/P-loop; other site
699034007700	ATP binding site [chemical binding]; other site
699034007701	Q-loop/lid; other site
699034007702	ABC transporter signature motif; other site
699034007703	Walker B; other site
699034007704	D-loop; other site
699034007705	H-loop/switch region; other site
699034007706	Domain of unknown function (DUF4213); Region: DUF4213; pfam13938
699034007707	Domain of unknown function (DUF364); Region: DUF364; pfam04016
699034007708	GlcNAc-PI de-N-acetylase; Region: PIG-L; pfam02585
699034007709	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034007710	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034007711	active site
699034007712	phosphorylation site [posttranslational modification]
699034007713	intermolecular recognition site; other site
699034007714	dimerization interface [polypeptide binding]; other site
699034007715	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034007716	DNA binding site [nucleotide binding]
699034007717	Polysaccharide biosynthesis C-terminal domain; Region: Polysacc_synt_C; pfam14667
699034007718	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034007719	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
699034007720	dimerization interface [polypeptide binding]; other site
699034007721	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034007722	dimer interface [polypeptide binding]; other site
699034007723	phosphorylation site [posttranslational modification]
699034007724	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034007725	ATP binding site [chemical binding]; other site
699034007726	Mg2+ binding site [ion binding]; other site
699034007727	G-X-G motif; other site
699034007728	The phosphomannomutase/phosphoglucomutase (PMM/PGM) bifunctional enzyme catalyzes the reversible conversion of 1-phospho to 6-phospho-sugars (e.g. between mannose-1-phosphate and mannose-6-phosphate or glucose-1-phosphate and glucose-6-phosphate) via a...; Region: PMM_PGM; cd03089
699034007729	active site
699034007730	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
699034007731	substrate binding site [chemical binding]; other site
699034007732	metal binding site [ion binding]; metal-binding site
699034007733	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
699034007734	substrate binding site [chemical binding]; other site
699034007735	hexamer interface [polypeptide binding]; other site
699034007736	metal binding site [ion binding]; metal-binding site
699034007737	Ribose/Galactose Isomerase; Region: LacAB_rpiB; pfam02502
699034007738	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
699034007739	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
699034007740	PYR/PP interface [polypeptide binding]; other site
699034007741	dimer interface [polypeptide binding]; other site
699034007742	TPP binding site [chemical binding]; other site
699034007743	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
699034007744	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
699034007745	TPP-binding site [chemical binding]; other site
699034007746	dimer interface [polypeptide binding]; other site
699034007747	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
699034007748	Alcohol dehydrogenases of the MDR family; Region: Zn_ADH4; cd08258
699034007749	putative NAD(P) binding site [chemical binding]; other site
699034007750	catalytic Zn binding site [ion binding]; other site
699034007751	structural Zn binding site [ion binding]; other site
699034007752	Threonine dehydrogenase and related Zn-dependent dehydrogenases [Amino acid transport and metabolism / General function prediction only]; Region: Tdh; COG1063
699034007753	NAD(P)-dependent sugar dehydrogenases; Region: sugar_DH; cd08236
699034007754	putative NAD(P) binding site [chemical binding]; other site
699034007755	catalytic Zn binding site [ion binding]; other site
699034007756	Phosphotransferase system, galactitol-specific IIC component [Carbohydrate transport and metabolism]; Region: GatC; COG3775
699034007757	PTS_IIB_galactitol: subunit IIB of enzyme II (EII) of the galactitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS).  In this system, EII is a galactitol-specific permease with two cytoplasmic domains (IIA and IIB) and a...; Region: PTS_IIB_galactitol; cd05566
699034007758	active site
699034007759	P-loop; other site
699034007760	phosphorylation site [posttranslational modification]
699034007761	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
699034007762	active site
699034007763	phosphorylation site [posttranslational modification]
699034007764	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
699034007765	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034007766	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
699034007767	Walker A motif; other site
699034007768	ATP binding site [chemical binding]; other site
699034007769	Walker B motif; other site
699034007770	arginine finger; other site
699034007771	PRD domain; Region: PRD; pfam00874
699034007772	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
699034007773	active pocket/dimerization site; other site
699034007774	active site
699034007775	phosphorylation site [posttranslational modification]
699034007776	PTS system, Lactose/Cellobiose specific IIB subunit; Region: PTS_IIB; pfam02302
699034007777	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
699034007778	active site
699034007779	phosphorylation site [posttranslational modification]
699034007780	Transaldolase-like fructose-6-phosphate aldolases (FSA) found in bacteria and archaea; Region: Transaldolase_FSA; cd00956
699034007781	active site
699034007782	intersubunit interactions; other site
699034007783	catalytic residue [active]
699034007784	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
699034007785	active site
699034007786	mannitol-1-phosphate 5-dehydrogenase; Provisional; Region: PRK02318
699034007787	Mannitol dehydrogenase Rossmann domain; Region: Mannitol_dh; pfam01232
699034007788	Mannitol dehydrogenase C-terminal domain; Region: Mannitol_dh_C; pfam08125
699034007789	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
699034007790	active site
699034007791	phosphorylation site [posttranslational modification]
699034007792	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
699034007793	HTH domain; Region: HTH_11; cl17392
699034007794	PRD domain; Region: PRD; pfam00874
699034007795	PRD domain; Region: PRD; pfam00874
699034007796	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
699034007797	active site
699034007798	P-loop; other site
699034007799	phosphorylation site [posttranslational modification]
699034007800	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cl00163
699034007801	Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism]; Region: MtlA; COG2213
699034007802	PTS system, mannitol-specific IIC component; Region: mtlA; TIGR00851
699034007803	PTS_IIB_mannitol: subunit IIB of enzyme II (EII) of the mannitol-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is a mannitol-specific permease with two cytoplasmic domains (IIA and IIB) and a transmembrane...; Region: PTS_IIB_mannitol; cd05567
699034007804	active site
699034007805	P-loop; other site
699034007806	phosphorylation site [posttranslational modification]
699034007807	inosine 5-monophosphate dehydrogenase; Validated; Region: PRK07107
699034007808	IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of...; Region: IMPDH; cd00381
699034007809	active site
699034007810	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the inosine 5' monophosphate dehydrogenase (IMPDH) protein.  IMPDH is an essential enzyme that catalyzes the first step unique to GTP synthesis, playing a...; Region: CBS_pair_IMPDH_2; cd04602
699034007811	Toxic anion resistance protein (TelA); Region: TelA; pfam05816
699034007812	Multidrug and toxic compound extrusion family and similar proteins; Region: MATE_like; cl09326
699034007813	5-bromo-4-chloroindolyl phosphate hydrolysis protein; Region: Halogen_Hydrol; cl02059
699034007814	Alcohol dehydrogenase, class IV [Energy production and conversion]; Region: EutG; COG1454
699034007815	active site
699034007816	NAD binding site [chemical binding]; other site
699034007817	metal binding site [ion binding]; metal-binding site
699034007818	Acetyl-CoA hydrolase [Energy production and conversion]; Region: ACH1; COG0427
699034007819	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
699034007820	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
699034007821	Aromatic ring hydroxylase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG2368
699034007822	4-hydroxyphenylacetate 3-hydroxylase C terminal; Region: HpaB; pfam03241
699034007823	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
699034007824	NAD-dependent aldehyde dehydrogenases [Energy production and conversion]; Region: PutA; COG1012
699034007825	putative catalytic cysteine [active]
699034007826	Acetyl-CoA hydrolase/transferase N-terminal domain; Region: AcetylCoA_hydro; pfam02550
699034007827	succinate CoA transferase; Region: YgfH_subfam; TIGR03458
699034007828	Acetyl-CoA hydrolase/transferase C-terminal domain; Region: AcetylCoA_hyd_C; pfam13336
699034007829	Predicted permease [General function prediction only]; Region: COG2985
699034007830	Predicted Permease Membrane Region; Region: Asp-Al_Ex; cl06061
699034007831	Predicted Permease Membrane Region; Region: Asp-Al_Ex; pfam06826
699034007832	Transcriptional regulator [Transcription]; Region: LysR; COG0583
699034007833	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
699034007834	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
699034007835	dimerization interface [polypeptide binding]; other site
699034007836	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
699034007837	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
699034007838	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
699034007839	active site
699034007840	Fatty acid synthesis protein; Region: FA_synthesis; cl17261
699034007841	"initiating" condensing enzymes are a subclass of decarboxylating condensing enzymes, including beta-ketoacyl [ACP] synthase, type III and polyketide synthases, type III, which include chalcone synthase and related enzymes. They are...; Region: init_cond_enzymes; cd00827
699034007842	dimer interface [polypeptide binding]; other site
699034007843	active site
699034007844	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB); Region: GRDB; cl19416
699034007845	Glycine/sarcosine/betaine reductase selenoprotein B (GRDB); Region: GRDB; pfam07355
699034007846	potential frameshift: common BLAST hit: gi|260687590|ref|YP_003218724.1| glycine/sarcosine/betaine reductase complex protein A
699034007847	Glycine/sarcosine/betaine reductase component B subunits; Region: Gly_reductase; pfam09338
699034007848	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
699034007849	catalytic residues [active]
699034007850	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
699034007851	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
699034007852	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_1; cd09606
699034007853	oligoendopeptidase, M3 family; Region: M3_not_pepF; TIGR02289
699034007854	active site
699034007855	Zn binding site [ion binding]; other site
699034007856	sugar phosphate phosphatase; Provisional; Region: PRK10513
699034007857	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
699034007858	active site
699034007859	motif I; other site
699034007860	motif II; other site
699034007861	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
699034007862	Alkylmercury lyase; Region: MerB; pfam03243
699034007863	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
699034007864	ATP-binding cassette domain of the nitrate and sulfonate transporters; Region: ABC_NrtD_SsuB_transporters; cd03293
699034007865	Walker A/P-loop; other site
699034007866	ATP binding site [chemical binding]; other site
699034007867	Q-loop/lid; other site
699034007868	ABC transporter signature motif; other site
699034007869	Walker B; other site
699034007870	D-loop; other site
699034007871	H-loop/switch region; other site
699034007872	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
699034007873	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
699034007874	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034007875	dimer interface [polypeptide binding]; other site
699034007876	conserved gate region; other site
699034007877	ABC-ATPase subunit interface; other site
699034007878	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
699034007879	substrate binding pocket [chemical binding]; other site
699034007880	membrane-bound complex binding site; other site
699034007881	hinge residues; other site
699034007882	DNA-binding transcriptional repressor LrhA; Provisional; Region: PRK15092
699034007883	ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components [Inorganic ion transport and metabolism]; Region: TauA; COG0715
699034007884	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; cl19131
699034007885	Predicted permeases [General function prediction only]; Region: COG0701
699034007886	DsrE/DsrF-like family; Region: DrsE; cl00672
699034007887	Nicotinate-nucleotide pyrophosphorylase [Coenzyme metabolism]; Region: NadC; COG0157
699034007888	Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase), also called nicotinate-nucleotide pyrophosphorylase, is involved in the de novo synthesis of NAD in both prokaryotes and eukaryotes. It catalyses the reaction of quinolinic acid (QA) with...; Region: QPRTase; cd01572
699034007889	dimerization interface [polypeptide binding]; other site
699034007890	active site
699034007891	L-aspartate oxidase; Provisional; Region: PRK06175
699034007892	FAD binding domain; Region: FAD_binding_2; pfam00890
699034007893	Quinolinate synthetase A protein; Region: NadA; pfam02445
699034007894	Carbon starvation protein CstA; Region: CstA; pfam02554
699034007895	Carbon starvation protein, predicted membrane protein [Signal transduction mechanisms]; Region: CstA; COG1966
699034007896	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
699034007897	Domain of Unknown Function (DUF1540); Region: DUF1540; pfam07561
699034007898	Predicted permease, member of the PurR regulon [General function prediction only]; Region: yhhT; COG0628
699034007899	Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+...; Region: Nudix_Hydrolase; cl00447
699034007900	nudix motif; other site
699034007901	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
699034007902	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
699034007903	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
699034007904	butyrate kinase; Provisional; Region: PRK03011
699034007905	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
699034007906	nucleotide binding site [chemical binding]; other site
699034007907	indolepyruvate oxidoreductase subunit beta; Reviewed; Region: PRK06853
699034007908	indolepyruvate ferredoxin oxidoreductase, alpha subunit; Region: IOR_alpha; TIGR03336
699034007909	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
699034007910	dimer interface [polypeptide binding]; other site
699034007911	PYR/PP interface [polypeptide binding]; other site
699034007912	TPP binding site [chemical binding]; other site
699034007913	substrate binding site [chemical binding]; other site
699034007914	Thiamine pyrophosphate (TPP) family, IOR-alpha subfamily, TPP-binding module; composed of proteins similar to indolepyruvate ferredoxin oxidoreductase (IOR) alpha subunit. IOR catalyzes the oxidative decarboxylation of arylpyruvates, such as...; Region: TPP_IOR_alpha; cd02008
699034007915	TPP-binding site; other site
699034007916	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
699034007917	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
699034007918	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
699034007919	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034007920	homodimer interface [polypeptide binding]; other site
699034007921	catalytic residue [active]
699034007922	Propionate catabolism activator; Region: PrpR_N; pfam06506
699034007923	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
699034007924	PAS domain; Region: PAS; smart00091
699034007925	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034007926	Walker A motif; other site
699034007927	ATP binding site [chemical binding]; other site
699034007928	Walker B motif; other site
699034007929	arginine finger; other site
699034007930	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
699034007931	metal binding site [ion binding]; metal-binding site
699034007932	active site
699034007933	I-site; other site
699034007934	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
699034007935	metal binding site [ion binding]; metal-binding site
699034007936	active site
699034007937	I-site; other site
699034007938	Protein of unknown function (DUF3785); Region: DUF3785; pfam12653
699034007939	Family of homologous FMN-dependent alpha-hydroxyacid oxidizing enzymes. This family occurs in both prokaryotes and eukaryotes. Members of this family include flavocytochrome b2 (FCB2), glycolate oxidase (GOX), lactate monooxygenase (LMO), mandelate...; Region: alpha_hydroxyacid_oxid_FMN; cd02809
699034007940	FMN-dependent dehydrogenase; Region: FMN_dh; pfam01070
699034007941	active site
699034007942	FMN binding site [chemical binding]; other site
699034007943	substrate binding site [chemical binding]; other site
699034007944	putative catalytic residues [active]
699034007945	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
699034007946	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
699034007947	Penicillinase repressor; Region: Penicillinase_R; cl17580
699034007948	Putative peptidoglycan binding domain; Region: PG_binding_1; pfam01471
699034007949	Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane]; Region: COG3409
699034007950	BlaR1 peptidase M56; Region: Peptidase_M56; pfam05569
699034007951	Penicillinase repressor; Region: Pencillinase_R; pfam03965
699034007952	Protein of unknown function (DUF2975); Region: DUF2975; pfam11188
699034007953	Solo B3/4 domain (OB-fold DNA/RNA-binding) of Phe-aaRS-beta [General function prediction only]; Region: COG3382
699034007954	Transglycosylase; Region: Transgly; pfam00912
699034007955	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
699034007956	active site
699034007957	catalytic site [active]
699034007958	substrate binding site [chemical binding]; other site
699034007959	MORN repeat; Region: MORN; cl14787
699034007960	Flavin Reductases; Region: FlaRed; cl00801
699034007961	DEDDh 3'-5' exonuclease domain of Caenorhabditis elegans ERI-1, human 3' exonuclease, and similar proteins; Region: ERI-1_3'hExo_like; cd06133
699034007962	active site
699034007963	catalytic site [active]
699034007964	substrate binding site [chemical binding]; other site
699034007965	tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional; Region: PRK10696
699034007966	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
699034007967	Ligand Binding Site [chemical binding]; other site
699034007968	Spore coat associated protein JA (CotJA); Region: CotJA; pfam11007
699034007969	CotJB protein; Region: CotJB; pfam12652
699034007970	Mn-containing catalase [Inorganic ion transport and metabolism]; Region: COG3546
699034007971	dinuclear metal binding motif [ion binding]; other site
699034007972	Bacterial SH3 domain; Region: SH3_3; pfam08239
699034007973	Bacterial SH3 domain; Region: SH3_3; pfam08239
699034007974	Bacterial SH3 domain; Region: SH3_3; pfam08239
699034007975	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
699034007976	NlpC/P60 family; Region: NLPC_P60; pfam00877
699034007977	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
699034007978	trimer interface [polypeptide binding]; other site
699034007979	active site
699034007980	DNA topoisomerase III; Provisional; Region: PRK07726
699034007981	TOPRIM_TopoIA_TopoIII: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to topoisomerase III. Type IA DNA topoisomerases remove (relax) negative supercoils in the DNA by: cleaving...; Region: TOPRIM_TopoIA_TopoIII; cd03362
699034007982	active site
699034007983	putative interdomain interaction site [polypeptide binding]; other site
699034007984	putative metal-binding site [ion binding]; other site
699034007985	putative nucleotide binding site [chemical binding]; other site
699034007986	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
699034007987	domain I; other site
699034007988	DNA binding groove [nucleotide binding]
699034007989	phosphate binding site [ion binding]; other site
699034007990	domain II; other site
699034007991	domain III; other site
699034007992	nucleotide binding site [chemical binding]; other site
699034007993	catalytic site [active]
699034007994	domain IV; other site
699034007995	C-terminal repeat of topoisomerase; Region: Toprim_Crpt; pfam13342
699034007996	Transcriptional regulators [Transcription]; Region: MarR; COG1846
699034007997	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
699034007998	dimerization interface [polypeptide binding]; other site
699034007999	putative Zn2+ binding site [ion binding]; other site
699034008000	putative DNA binding site [nucleotide binding]; other site
699034008001	RND family efflux transporter, MFP subunit; Region: RND_mfp; TIGR01730
699034008002	Biotin-lipoyl like; Region: Biotin_lipoyl_2; pfam13533
699034008003	Biotin-lipoyl like; Region: Biotin_lipoyl_2; cl19169
699034008004	HlyD family secretion protein; Region: HlyD_3; pfam13437
699034008005	Cation/multidrug efflux pump [Defense mechanisms]; Region: AcrB; COG0841
699034008006	MMPL family; Region: MMPL; cl14618
699034008007	MMPL family; Region: MMPL; cl14618
699034008008	Outer membrane efflux protein; Region: OEP; pfam02321
699034008009	Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: TolC; COG1538
699034008010	putative transposase OrfB; Reviewed; Region: PHA02517
699034008011	HTH-like domain; Region: HTH_21; pfam13276
699034008012	Integrase core domain; Region: rve; pfam00665
699034008013	Integrase core domain; Region: rve_2; pfam13333
699034008014	Helix-turn-helix domain; Region: HTH_28; pfam13518
699034008015	NMD3 family; Region: NMD3; pfam04981
699034008016	pyruvate phosphate dikinase; Provisional; Region: PRK09279
699034008017	Pyruvate phosphate dikinase, PEP/pyruvate binding domain; Region: PPDK_N; pfam01326
699034008018	PEP-utilizing enzyme, mobile domain; Region: PEP-utilizers; pfam00391
699034008019	PEP-utilizing enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
699034008020	PEP synthetase regulatory protein; Provisional; Region: PRK05339
699034008021	HTH domain; Region: HTH_11; pfam08279
699034008022	FOG: CBS domain [General function prediction only]; Region: COG0517
699034008023	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_4; cd04617
699034008024	Predicted homoserine dehydrogenase [Amino acid transport and metabolism]; Region: COG4091
699034008025	SAF domain of putative dehydrogenases or oxidoreductases; Region: SAF_DH_OX_like; cd11616
699034008026	PTS system glucitol/sorbitol-specific IIA component; Region: PTSIIA_gutA; pfam03829
699034008027	Glucitol operon activator protein (GutM); Region: GutM; pfam06923
699034008028	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
699034008029	HTH domain; Region: HTH_11; pfam08279
699034008030	Mga helix-turn-helix domain; Region: Mga; pfam05043
699034008031	PRD domain; Region: PRD; pfam00874
699034008032	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
699034008033	active site
699034008034	P-loop; other site
699034008035	phosphorylation site [posttranslational modification]
699034008036	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; Region: PTS_EIIA_2; pfam00359
699034008037	active site
699034008038	phosphorylation site [posttranslational modification]
699034008039	Phosphotransferase system sorbitol-specific component IIBC [Carbohydrate transport and metabolism]; Region: SrlE; COG3732
699034008040	Sorbitol phosphotransferase enzyme II N-terminus; Region: EIIBC-GUT_N; pfam03612
699034008041	Sorbitol phosphotransferase enzyme II C-terminus; Region: EIIBC-GUT_C; pfam07663
699034008042	PTS system enzyme II sorbitol-specific factor; Region: EII-GUT; pfam03608
699034008043	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
699034008044	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
699034008045	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
699034008046	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
699034008047	Choloylglycine hydrolase (CGH)_like. This family of choloylglycine hydrolase-like proteins includes conjugated bile acid hydrolase (CBAH), penicillin V acylase (PVA), acid ceramidase (AC), and N-acylethanolamine-hydrolyzing acid amidase (NAAA) which...; Region: Ntn_CGH_like; cd01935
699034008048	active site
699034008049	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
699034008050	M20 Peptidase Aminoacylase 1-like protein 2-like, amidohydrolase subfamily; Region: M20_ACY1L2_like; cd05672
699034008051	metal binding site [ion binding]; metal-binding site
699034008052	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
699034008053	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
699034008054	putative substrate translocation pore; other site
699034008055	Major Facilitator Superfamily; Region: MFS_1; pfam07690
699034008056	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
699034008057	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
699034008058	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034008059	homodimer interface [polypeptide binding]; other site
699034008060	catalytic residue [active]
699034008061	Phosphate acetyl/butaryl transferase; Region: PTA_PTB; cl17212
699034008062	butyrate kinase; Provisional; Region: PRK03011
699034008063	Pyruvate ferredoxin/flavodoxin oxidoreductase; Region: POR; pfam01558
699034008064	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit [Energy production and conversion]; Region: PorB; COG1013
699034008065	Thiamine pyrophosphate (TPP) enzyme family, TPP-binding module; found in many key metabolic enzymes which use TPP (also known as thiamine diphosphate) as a cofactor. These enzymes include, among others, the E1 components of the pyruvate, the acetoin and...; Region: TPP_enzymes; cl01629
699034008066	TPP-binding site [chemical binding]; other site
699034008067	2-ketoisovalerate ferredoxin reductase; Validated; Region: PRK07119
699034008068	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
699034008069	dimer interface [polypeptide binding]; other site
699034008070	PYR/PP interface [polypeptide binding]; other site
699034008071	TPP binding site [chemical binding]; other site
699034008072	substrate binding site [chemical binding]; other site
699034008073	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
699034008074	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
699034008075	Transcriptional regulator [Transcription]; Region: IclR; COG1414
699034008076	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
699034008077	putative DNA binding site [nucleotide binding]; other site
699034008078	putative Zn2+ binding site [ion binding]; other site
699034008079	Bacterial transcriptional regulator; Region: IclR; pfam01614
699034008080	Sulfite reductase, beta subunit (hemoprotein) [Inorganic ion transport and metabolism]; Region: CysI; COG0155
699034008081	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
699034008082	Nitrite and sulphite reductase 4Fe-4S domain; Region: NIR_SIR; pfam01077
699034008083	Nitrite/Sulfite reductase ferredoxin-like half domain; Region: NIR_SIR_ferr; pfam03460
699034008084	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
699034008085	glycyl-tRNA synthetase subunit beta; Validated; Region: glyS; PRK01233
699034008086	Glycyl-tRNA synthetase beta subunit; Region: tRNA_synt_2f; pfam02092
699034008087	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
699034008088	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
699034008089	dimer interface [polypeptide binding]; other site
699034008090	motif 1; other site
699034008091	active site
699034008092	motif 2; other site
699034008093	motif 3; other site
699034008094	Domain of unknown function (DUF4342); Region: DUF4342; pfam14242
699034008095	DNA repair protein RecO; Reviewed; Region: recO; PRK00085
699034008096	Recombination protein O N terminal; Region: RecO_N; pfam11967
699034008097	Recombination protein O C terminal; Region: RecO_C; pfam02565
699034008098	YqzL-like protein; Region: YqzL; pfam14006
699034008099	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
699034008100	MgtE intracellular N domain; Region: MgtE_N; pfam03448
699034008101	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
699034008102	Divalent cation transporter; Region: MgtE; cl00786
699034008103	GTPase Era; Reviewed; Region: era; PRK00089
699034008104	E. coli Ras-like protein (Era) is a multifunctional GTPase; Region: Era; cd04163
699034008105	G1 box; other site
699034008106	GTP/Mg2+ binding site [chemical binding]; other site
699034008107	Switch I region; other site
699034008108	G2 box; other site
699034008109	Switch II region; other site
699034008110	G3 box; other site
699034008111	G4 box; other site
699034008112	G5 box; other site
699034008113	KH domain; Region: KH_2; pfam07650
699034008114	Cytidine deaminase zinc-binding domain. These enzymes are Zn dependent. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a water molecule to form a hydroxide ion that performs a nucleophilic attack on...; Region: cytidine_deaminase; cd01283
699034008115	active site
699034008116	catalytic motif [active]
699034008117	Zn binding site [ion binding]; other site
699034008118	Integral membrane undecaprenol kinase domain co-occurring with type 2 phosphatidic acid phosphatase-like domains; Region: UDPK_IM_PAP2_like; cd14266
699034008119	trimer interface [polypeptide binding]; other site
699034008120	putative active site [active]
699034008121	Zn binding site [ion binding]; other site
699034008122	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
699034008123	active site
699034008124	metal-binding heat shock protein; Provisional; Region: PRK00016
699034008125	Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms]; Region: PhoH; COG1702
699034008126	PhoH-like protein; Region: PhoH; pfam02562
699034008127	sporulation protein YqfD; Region: spore_yqfD; TIGR02876
699034008128	Putative stage IV sporulation protein YqfD; Region: YqfD; pfam06898
699034008129	YabP family; Region: YabP; pfam07873
699034008130	RaiA ("ribosome-associated inhibitor A", also known as Protein Y (PY), YfiA, and SpotY,  is a stress-response protein that binds the ribosomal subunit interface and arrests translation by interfering with aminoacyl-tRNA binding to the ribosomal...; Region: RaiA; cd00552
699034008131	30S subunit binding site; other site
699034008132	TspO/MBR family; Region: TspO_MBR; pfam03073
699034008133	Yqey-like protein; Region: YqeY; pfam09424
699034008134	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
699034008135	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
699034008136	nucleotide binding site/active site [active]
699034008137	HIT family signature motif; other site
699034008138	catalytic residue [active]
699034008139	2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]; Region: MiaB; COG0621
699034008140	Uncharacterized protein family UPF0004; Region: UPF0004; pfam00919
699034008141	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
699034008142	FeS/SAM binding site; other site
699034008143	16S ribosomal RNA methyltransferase RsmE; Provisional; Region: PRK11713
699034008144	RNA methyltransferase, RsmE family; Region: TIGR00046
699034008145	ribosomal protein L11 methyltransferase; Reviewed; Region: prmA; PRK00517
699034008146	Medium chain reductase/dehydrogenase (MDR)/zinc-dependent alcohol dehydrogenase-like family; Region: MDR; cl16912
699034008147	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
699034008148	S-adenosylmethionine binding site [chemical binding]; other site
699034008149	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
699034008150	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
699034008151	CRISPR/Cas system-associated protein Cas3; Region: Cas3_I; cd09639
699034008152	CRISPR-associated helicase Cas3; Region: cas3_core; TIGR01587
699034008153	ATP binding site [chemical binding]; other site
699034008154	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-B; cd09658
699034008155	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I-C; cd09687
699034008156	CRISPR/Cas system-associated RAMP superfamily protein Cas6; Region: Cas6-I-III; cd09652
699034008157	glycerol-3-phosphate transporter ATP-binding subunit; Provisional; Region: ugpC; PRK11650
699034008158	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
699034008159	Walker A/P-loop; other site
699034008160	ATP binding site [chemical binding]; other site
699034008161	Q-loop/lid; other site
699034008162	ABC transporter signature motif; other site
699034008163	Walker B; other site
699034008164	D-loop; other site
699034008165	H-loop/switch region; other site
699034008166	TOBE domain; Region: TOBE_2; pfam08402
699034008167	PucR C-terminal helix-turn-helix domain; Region: HTH_30; pfam13556
699034008168	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
699034008169	Major Facilitator Superfamily; Region: MFS_1; pfam07690
699034008170	putative substrate translocation pore; other site
699034008171	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
699034008172	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
699034008173	nucleotide binding site [chemical binding]; other site
699034008174	chaperone protein DnaJ; Provisional; Region: PRK10767
699034008175	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
699034008176	HSP70 interaction site [polypeptide binding]; other site
699034008177	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
699034008178	substrate binding site [polypeptide binding]; other site
699034008179	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
699034008180	Zn binding sites [ion binding]; other site
699034008181	dimer interface [polypeptide binding]; other site
699034008182	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
699034008183	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
699034008184	nucleotide binding site [chemical binding]; other site
699034008185	NEF interaction site [polypeptide binding]; other site
699034008186	SBD interface [polypeptide binding]; other site
699034008187	Apolipophorin-III and similar insect proteins; Region: ApoLp-III_like; cl19113
699034008188	GrpE; Region: GrpE; pfam01025
699034008189	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
699034008190	dimer interface [polypeptide binding]; other site
699034008191	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
699034008192	heat-inducible transcription repressor; Provisional; Region: hrcA; PRK00082
699034008193	HrcA protein C terminal domain; Region: HrcA; pfam01628
699034008194	coproporphyrinogen III oxidase; Provisional; Region: PRK05799
699034008195	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
699034008196	FeS/SAM binding site; other site
699034008197	HemN C-terminal domain; Region: HemN_C; pfam06969
699034008198	Amino acid transporters [Amino acid transport and metabolism]; Region: PotE; COG0531
699034008199	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
699034008200	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
699034008201	tRNA CCA-pyrophosphorylase; Provisional; Region: PRK13299
699034008202	active site
699034008203	NTP binding site [chemical binding]; other site
699034008204	metal binding triad [ion binding]; metal-binding site
699034008205	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
699034008206	HD domain; Region: HD; pfam01966
699034008207	tRNA nucleotidyltransferase domain 2 putative; Region: tRNA_NucTran2_2; pfam13735
699034008208	GTP-binding protein LepA; Provisional; Region: PRK05433
699034008209	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
699034008210	G1 box; other site
699034008211	putative GEF interaction site [polypeptide binding]; other site
699034008212	GTP/Mg2+ binding site [chemical binding]; other site
699034008213	Switch I region; other site
699034008214	G2 box; other site
699034008215	G3 box; other site
699034008216	Switch II region; other site
699034008217	G4 box; other site
699034008218	G5 box; other site
699034008219	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
699034008220	Elongation Factor G, domain II; Region: EFG_II; pfam14492
699034008221	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
699034008222	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
699034008223	stage II sporulation protein P; Region: spore_II_P; TIGR02867
699034008224	germination protease; Provisional; Region: PRK12362
699034008225	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
699034008226	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
699034008227	dimerization interface [polypeptide binding]; other site
699034008228	putative DNA binding site [nucleotide binding]; other site
699034008229	putative Zn2+ binding site [ion binding]; other site
699034008230	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
699034008231	DNA polymerase III subunit delta; Reviewed; Region: holA; PRK05574
699034008232	DNA polymerase III, delta subunit; Region: DNA_pol3_delta; cl19912
699034008233	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
699034008234	Competence protein; Region: Competence; pfam03772
699034008235	Acetyltransferase (GNAT) domain; Region: Acetyltransf_9; pfam13527
699034008236	Predicted acetyltransferase involved in intracellular survival and related acetyltransferases [General function prediction only]; Region: Eis; COG4552
699034008237	Sterol carrier protein domain; Region: SCP2_2; pfam13530
699034008238	Uncharacterized conserved protein (DUF2156); Region: DUF2156; cl12090
699034008239	Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only]; Region: ComEC; COG2333
699034008240	Metallo-beta-lactamase superfamily; Region: Lactamase_B; smart00849
699034008241	Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism]; Region: COG1179
699034008242	Family of activating enzymes (E1) of ubiquitin-like proteins related to the E.coli hypothetical protein ygdL. The common reaction mechanism catalyzed by E1-like enzymes begins with a nucleophilic attack of the C-terminal carboxylate of the ubiquitin-like...; Region: YgdL_like; cd00755
699034008243	putative ATP binding site [chemical binding]; other site
699034008244	putative substrate interface [chemical binding]; other site
699034008245	Domain of unknown function (DUF348); Region: DUF348; pfam03990
699034008246	G5 domain; Region: G5; pfam07501
699034008247	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3584
699034008248	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
699034008249	ligand binding site [chemical binding]; other site
699034008250	active site
699034008251	UGI interface [polypeptide binding]; other site
699034008252	catalytic site [active]
699034008253	Listerrria innocua Lin0431  is similar to the N-Utilization Substance G (NusG) N terminal (NGN) insert (DII); Region: Lin0431_like; cd09911
699034008254	trimer interface [polypeptide binding]; other site
699034008255	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
699034008256	putative C-S lyase; Region: C_S_lyase_PatB; TIGR04350
699034008257	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
699034008258	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034008259	homodimer interface [polypeptide binding]; other site
699034008260	catalytic residue [active]
699034008261	aminopeptidase; Provisional; Region: PRK09795
699034008262	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
699034008263	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
699034008264	active site
699034008265	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
699034008266	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
699034008267	active site
699034008268	P-loop; other site
699034008269	phosphorylation site [posttranslational modification]
699034008270	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
699034008271	active site
699034008272	phosphorylation site [posttranslational modification]
699034008273	putative frv operon regulatory protein; Provisional; Region: PRK09863
699034008274	HTH domain; Region: HTH_11; pfam08279
699034008275	Mga helix-turn-helix domain; Region: Mga; pfam05043
699034008276	PRD domain; Region: PRD; pfam00874
699034008277	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
699034008278	active site
699034008279	P-loop; other site
699034008280	phosphorylation site [posttranslational modification]
699034008281	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
699034008282	active site
699034008283	phosphorylation site [posttranslational modification]
699034008284	M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides; Region: M20_PepV; cd03888
699034008285	dipeptidase, putative; Region: dipeptidaselike; TIGR01887
699034008286	active site
699034008287	metal binding site [ion binding]; metal-binding site
699034008288	Phosphomannose isomerase [Carbohydrate transport and metabolism]; Region: ManA; COG1482
699034008289	Alpha-Mannosidase Binding Domain of Atg19/34; Region: ABD; cl19057
699034008290	PAS domain S-box; Region: sensory_box; TIGR00229
699034008291	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
699034008292	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034008293	dimer interface [polypeptide binding]; other site
699034008294	phosphorylation site [posttranslational modification]
699034008295	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034008296	ATP binding site [chemical binding]; other site
699034008297	Mg2+ binding site [ion binding]; other site
699034008298	G-X-G motif; other site
699034008299	Selenocysteine-specific translation elongation factor [Translation, ribosomal structure and biogenesis]; Region: SelB; COG3276
699034008300	SelB, the dedicated elongation factor for delivery of selenocysteinyl-tRNA to the ribosome; Region: SelB; cd04171
699034008301	G1 box; other site
699034008302	putative GEF interaction site [polypeptide binding]; other site
699034008303	GTP/Mg2+ binding site [chemical binding]; other site
699034008304	Switch I region; other site
699034008305	G2 box; other site
699034008306	G3 box; other site
699034008307	Switch II region; other site
699034008308	G4 box; other site
699034008309	G5 box; other site
699034008310	selB_II: this subfamily represents the domain of elongation factor SelB, homologous to domain II of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several...; Region: selB_II; cd03696
699034008311	This family represents the domain of elongation factor SelB, homologous to domain III of EF-Tu. SelB may function by replacing EF-Tu. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements:...; Region: selB_III; cd04094
699034008312	Elongation factor SelB, winged helix; Region: SelB-wing_2; pfam09106
699034008313	Elongation factor SelB, winged helix; Region: SelB-wing_3; pfam09107
699034008314	seryl-tRNA(sec) selenium transferase; Region: selA; TIGR00474
699034008315	Selenocysteine synthase N terminal; Region: Se-cys_synth_N; pfam12390
699034008316	L-seryl-tRNA selenium transferase; Region: SelA; pfam03841
699034008317	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
699034008318	catalytic residue [active]
699034008319	Selenophosphate synthetase  (SelD) catalyzes the conversion of selenium to selenophosphate which is required by a number of bacterial, archaeal and eukaryotic organisms for synthesis of Secys-tRNA, the precursor of selenocysteine in selenoenzymes. The...; Region: SelD; cd02195
699034008320	dimerization interface [polypeptide binding]; other site
699034008321	putative ATP binding site [chemical binding]; other site
699034008322	SLBB domain; Region: SLBB; pfam10531
699034008323	comEA protein; Region: comE; TIGR01259
699034008324	Helix-hairpin-helix motif; Region: HHH_3; pfam12836
699034008325	D-alanyl-D-alanine carboxypeptidase; Provisional; Region: dacD; PRK11397
699034008326	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl19191
699034008327	Penicillin-binding protein 5, C-terminal domain; Region: PBP5_C; smart00936
699034008328	Uncharacterized protein conserved in bacteria (DUF2325); Region: DUF2325; pfam10087
699034008329	argininosuccinate lyase; Provisional; Region: PRK00855
699034008330	Argininosuccinate lyase (argininosuccinase, ASAL); Region: Argininosuccinate_lyase; cd01359
699034008331	active sites [active]
699034008332	tetramer interface [polypeptide binding]; other site
699034008333	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
699034008334	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
699034008335	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
699034008336	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
699034008337	L-threonine-O-3-phosphate decarboxylase; Region: L_thr_O3P_dcar; TIGR01140
699034008338	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034008339	homodimer interface [polypeptide binding]; other site
699034008340	catalytic residue [active]
699034008341	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
699034008342	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
699034008343	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
699034008344	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
699034008345	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
699034008346	motif II; other site
699034008347	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
699034008348	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: VanY; COG1876
699034008349	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
699034008350	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
699034008351	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
699034008352	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
699034008353	Major Facilitator Superfamily; Region: MFS_1; pfam07690
699034008354	putative substrate translocation pore; other site
699034008355	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
699034008356	Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism]; Region: COG1305
699034008357	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
699034008358	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
699034008359	NAD-dependent, lactate dehydrogenase-like, 2-hydroxycarboxylate dehydrogenase family; Region: LDH_MDH_like; cl17195
699034008360	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
699034008361	NAD(P) binding site [chemical binding]; other site
699034008362	LDH/MDH dimer interface [polypeptide binding]; other site
699034008363	substrate binding site [chemical binding]; other site
699034008364	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
699034008365	PTS system, alpha-glucoside-specific IIBC component; Region: PTS-IIBC-alpha; TIGR02005
699034008366	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
699034008367	active site turn [active]
699034008368	phosphorylation site [posttranslational modification]
699034008369	transcriptional antiterminator BglG; Provisional; Region: PRK09772
699034008370	CAT RNA binding domain; Region: CAT_RBD; smart01061
699034008371	PRD domain; Region: PRD; pfam00874
699034008372	PRD domain; Region: PRD; pfam00874
699034008373	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
699034008374	HPr interaction site; other site
699034008375	glycerol kinase (GK) interaction site [polypeptide binding]; other site
699034008376	active site
699034008377	phosphorylation site [posttranslational modification]
699034008378	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
699034008379	homotrimer interaction site [polypeptide binding]; other site
699034008380	putative active site [active]
699034008381	threonine dehydratase; Provisional; Region: PRK08198
699034008382	Threonine dehydratase: The first step in amino acid degradation is the removal of nitrogen. Although the nitrogen atoms of most amino acids are transferred to alpha-ketoglutarate before removal, the alpha-amino group of threonine can be directly...; Region: Thr-dehyd; cd01562
699034008383	tetramer interface [polypeptide binding]; other site
699034008384	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034008385	catalytic residue [active]
699034008386	C-terminal ACT domain of biodegradative (catabolic) threonine dehydratase II (ThrD-II) and other related ACT domains; Region: ACT_ThrD-II-like; cd04886
699034008387	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
699034008388	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
699034008389	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034008390	homodimer interface [polypeptide binding]; other site
699034008391	catalytic residue [active]
699034008392	cytoplasmic asparaginase I; Provisional; Region: ansA; PRK09461
699034008393	Type II (periplasmic) bacterial L-asparaginase; Region: L-asparaginase_II; cd08964
699034008394	active site
699034008395	homotetramer interface [polypeptide binding]; other site
699034008396	homodimer interface [polypeptide binding]; other site
699034008397	Dolichyl-phosphate-mannose-protein mannosyltransferase; Region: PMT_2; cl19158
699034008398	VanZ like family; Region: VanZ; pfam04892
699034008399	potential frameshift: common BLAST hit: gi|260687757|ref|YP_003218891.1| leucyl-tRNA synthetase
699034008400	iojap-like ribosome-associated protein; Region: iojap_ybeB; TIGR00090
699034008401	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
699034008402	Zn2+ binding site [ion binding]; other site
699034008403	Mg2+ binding site [ion binding]; other site
699034008404	Nicotinamide/nicotinate mononucleotide adenylyltransferase; Region: NMNAT; cd02165
699034008405	active site
699034008406	(T/H)XGH motif; other site
699034008407	recombination regulator RecX; Reviewed; Region: recX; PRK00117
699034008408	glycogen branching enzyme; Provisional; Region: PRK12313
699034008409	N-terminal Early set domain associated with the catalytic domain of eukaryotic glycogen branching enzyme (also called 1,4 alpha glucan branching enzyme); Region: E_set_GBE_euk_N; cd02854
699034008410	Alpha amylase catalytic domain found in bacterial and eukaryotic branching enzymes; Region: AmyAc_bac_euk_BE; cd11321
699034008411	active site
699034008412	catalytic site [active]
699034008413	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
699034008414	Helix-turn-helix domain; Region: HTH_18; pfam12833
699034008415	ECF-type riboflavin transporter, S component; Region: ECF-ribofla_trS; pfam07155
699034008416	Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase [Amino acid transport and metabolism]; Region: COG0075
699034008417	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
699034008418	catalytic residue [active]
699034008419	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
699034008420	FtsX-like permease family; Region: FtsX; pfam02687
699034008421	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
699034008422	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
699034008423	FtsX-like permease family; Region: FtsX; pfam02687
699034008424	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
699034008425	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
699034008426	Walker A/P-loop; other site
699034008427	ATP binding site [chemical binding]; other site
699034008428	Q-loop/lid; other site
699034008429	ABC transporter signature motif; other site
699034008430	Walker B; other site
699034008431	D-loop; other site
699034008432	H-loop/switch region; other site
699034008433	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034008434	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034008435	dimer interface [polypeptide binding]; other site
699034008436	phosphorylation site [posttranslational modification]
699034008437	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034008438	ATP binding site [chemical binding]; other site
699034008439	Mg2+ binding site [ion binding]; other site
699034008440	G-X-G motif; other site
699034008441	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034008442	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034008443	active site
699034008444	phosphorylation site [posttranslational modification]
699034008445	intermolecular recognition site; other site
699034008446	dimerization interface [polypeptide binding]; other site
699034008447	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034008448	DNA binding site [nucleotide binding]
699034008449	5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases [Nucleotide transport and metabolism]; Region: UshA; COG0737
699034008450	Staphylococcus aureus SA0022 and related proteins, N-terminal metallophosphatase domain; Region: MPP_SA0022_N; cd07408
699034008451	putative active site [active]
699034008452	putative metal binding site [ion binding]; other site
699034008453	5'-nucleotidase, C-terminal domain; Region: 5_nucleotid_C; pfam02872
699034008454	ribonuclease Z; Reviewed; Region: PRK00055
699034008455	coenzyme A disulfide reductase; Reviewed; Region: PRK09564
699034008456	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
699034008457	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
699034008458	Pyridine nucleotide-disulphide oxidoreductase, dimerization domain; Region: Pyr_redox_dim; pfam02852
699034008459	potential frameshift: common BLAST hit: gi|126700158|ref|YP_001089055.1| sodium:dicarboxylate symporter family protein
699034008460	DHHW protein; Region: DHHW; pfam14286
699034008461	Predicted membrane protein involved in D-alanine export [Cell envelope biogenesis, outer membrane]; Region: DltB; COG1696
699034008462	Phosphate transport (Pho88); Region: Pho88; cl02110
699034008463	Glycosyltransferases, probably involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG1215
699034008464	CESA_CelA_like are involved in the elongation of the glucan chain of cellulose; Region: CESA_CelA_like; cd06421
699034008465	DXD motif; other site
699034008466	PilZ domain; Region: PilZ; pfam07238
699034008467	Cellulase (glycosyl hydrolase family 5); Region: Cellulase; pfam00150
699034008468	Domain of unknown function (DUF4091); Region: DUF4091; pfam13320
699034008469	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
699034008470	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034008471	dimer interface [polypeptide binding]; other site
699034008472	conserved gate region; other site
699034008473	putative PBP binding loops; other site
699034008474	ABC-ATPase subunit interface; other site
699034008475	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
699034008476	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034008477	dimer interface [polypeptide binding]; other site
699034008478	conserved gate region; other site
699034008479	putative PBP binding loops; other site
699034008480	ABC-ATPase subunit interface; other site
699034008481	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
699034008482	Bacterial extracellular solute-binding protein; Region: SBP_bac_8; pfam13416
699034008483	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
699034008484	putative active site [active]
699034008485	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: ulaA; PRK09410
699034008486	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
699034008487	active site
699034008488	P-loop; other site
699034008489	phosphorylation site [posttranslational modification]
699034008490	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
699034008491	HTH domain; Region: HTH_11; pfam08279
699034008492	Mga helix-turn-helix domain; Region: Mga; pfam05043
699034008493	PRD domain; Region: PRD; pfam00874
699034008494	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
699034008495	active site
699034008496	P-loop; other site
699034008497	phosphorylation site [posttranslational modification]
699034008498	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
699034008499	active site
699034008500	phosphorylation site [posttranslational modification]
699034008501	hypothetical protein; Region: PHA00671
699034008502	Phosphopantetheine adenylyltransferase; Region: PPAT; cd02163
699034008503	active site
699034008504	(T/H)XGH motif; other site
699034008505	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
699034008506	S-adenosylmethionine binding site [chemical binding]; other site
699034008507	ATP-dependent DNA helicase RecG; Provisional; Region: PRK10917
699034008508	Y-family of DNA polymerases; Region: PolY; cl12025
699034008509	RecG_wedge_OBF: A subfamily of OB folds corresponding to the OB fold found in the N-terminal (wedge) domain of Escherichia coli RecG. RecG is a branched-DNA-specific helicase, which catalyzes the interconversion of a DNA replication fork to a...; Region: RecG_wedge_OBF; cd04488
699034008510	generic binding surface II; other site
699034008511	ssDNA binding site; other site
699034008512	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
699034008513	ATP binding site [chemical binding]; other site
699034008514	putative Mg++ binding site [ion binding]; other site
699034008515	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
699034008516	nucleotide binding region [chemical binding]; other site
699034008517	ATP-binding site [chemical binding]; other site
699034008518	DAK2 domain fusion protein YloV; Region: YloV; TIGR03599
699034008519	DAK2 domain; Region: Dak2; pfam02734
699034008520	Dihydroxyacetone kinase family; Region: Dak1_2; pfam13684
699034008521	Asp23 family; Region: Asp23; pfam03780
699034008522	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
699034008523	Putative transposase, YhgA-like; Region: Transposase_31; pfam04754
699034008524	Helix-Turn-Helix DNA binding domain of the transcription regulators TipAL, Mta, and SkgA; Region: HTH_TipAL-Mta; cd01106
699034008525	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
699034008526	DNA binding residues [nucleotide binding]
699034008527	dimer interface [polypeptide binding]; other site
699034008528	TipAS antibiotic-recognition domain; Region: TipAS; pfam07739
699034008529	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
699034008530	HTH domain; Region: HTH_11; pfam08279
699034008531	Mga helix-turn-helix domain; Region: Mga; pfam05043
699034008532	PRD domain; Region: PRD; pfam00874
699034008533	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
699034008534	active site
699034008535	P-loop; other site
699034008536	phosphorylation site [posttranslational modification]
699034008537	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
699034008538	active site
699034008539	phosphorylation site [posttranslational modification]
699034008540	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
699034008541	active site
699034008542	phosphorylation site [posttranslational modification]
699034008543	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
699034008544	active site
699034008545	P-loop; other site
699034008546	phosphorylation site [posttranslational modification]
699034008547	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
699034008548	alpha-mannosidase; Provisional; Region: PRK09819
699034008549	N-terminal catalytic domain of Escherichia coli alpha-mannosidase MngB and its bacterial homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_EcMngB_like; cd10815
699034008550	active site
699034008551	metal binding site [ion binding]; metal-binding site
699034008552	catalytic site [active]
699034008553	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; cl08536
699034008554	Glycosyl hydrolases family 38 C-terminal domain; Region: Glyco_hydro_38C; pfam07748
699034008555	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034008556	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034008557	dimer interface [polypeptide binding]; other site
699034008558	phosphorylation site [posttranslational modification]
699034008559	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034008560	ATP binding site [chemical binding]; other site
699034008561	Mg2+ binding site [ion binding]; other site
699034008562	G-X-G motif; other site
699034008563	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034008564	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034008565	active site
699034008566	phosphorylation site [posttranslational modification]
699034008567	intermolecular recognition site; other site
699034008568	dimerization interface [polypeptide binding]; other site
699034008569	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034008570	DNA binding site [nucleotide binding]
699034008571	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514
699034008572	FMN binding site [chemical binding]; other site
699034008573	dimer interface [polypeptide binding]; other site
699034008574	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
699034008575	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
699034008576	Thiamine pyrophosphokinase; Region: TPK; cd07995
699034008577	thiamine pyrophosphokinase; Region: thi_PPkinase; TIGR01378
699034008578	active site
699034008579	dimerization interface [polypeptide binding]; other site
699034008580	thiamine binding site [chemical binding]; other site
699034008581	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
699034008582	substrate binding site [chemical binding]; other site
699034008583	hexamer interface [polypeptide binding]; other site
699034008584	metal binding site [ion binding]; metal-binding site
699034008585	GTPase RsgA; Reviewed; Region: PRK00098
699034008586	S1_YloQ_GTPase: YloQ GTase family (also known as YjeQ and CpgA), S1-like RNA-binding domain. Proteins in the YloQ GTase family bind the ribosome and have GTPase activity. The precise role of this family is unknown. The protein structure is composed of...; Region: S1_YloQ_GTPase; cd04466
699034008587	RNA binding site [nucleotide binding]; other site
699034008588	homodimer interface [polypeptide binding]; other site
699034008589	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
699034008590	GTPase/Zn-binding domain interface [polypeptide binding]; other site
699034008591	GTP/Mg2+ binding site [chemical binding]; other site
699034008592	G4 box; other site
699034008593	G5 box; other site
699034008594	G1 box; other site
699034008595	Switch I region; other site
699034008596	G2 box; other site
699034008597	G3 box; other site
699034008598	Switch II region; other site
699034008599	3-ketoacyl-(acyl-carrier-protein) reductase; Provisional; Region: fabG; PRK05565
699034008600	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
699034008601	NAD(P) binding site [chemical binding]; other site
699034008602	active site
699034008603	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
699034008604	Catalytic domain of Protein Kinases; Region: PKc; cd00180
699034008605	active site
699034008606	ATP binding site [chemical binding]; other site
699034008607	substrate binding site [chemical binding]; other site
699034008608	activation loop (A-loop); other site
699034008609	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
699034008610	PASTA domain of bacterial serine/threonine kinase pknB-like proteins. PknB is a member of a group of related transmembrane sensor kinases present in many gram positive bacteria, which has been shown to regulate cell shape in Mycobacterium tubercolosis; Region: PASTA_pknB; cd06577
699034008611	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
699034008612	active site
699034008613	Predicted Fe-S-cluster redox enzyme [General function prediction only]; Region: COG0820
699034008614	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl18962
699034008615	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
699034008616	FeS/SAM binding site; other site
699034008617	16S rRNA methyltransferase B; Provisional; Region: PRK14902
699034008618	NusB family; Region: NusB; pfam01029
699034008619	putative RNA binding site [nucleotide binding]; other site
699034008620	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
699034008621	S-adenosylmethionine binding site [chemical binding]; other site
699034008622	Putative neutral zinc metallopeptidase; Region: Zn_peptidase_2; pfam04298
699034008623	Protein of unknown function DUF116; Region: DUF116; pfam01976
699034008624	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
699034008625	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
699034008626	putative active site [active]
699034008627	substrate binding site [chemical binding]; other site
699034008628	putative cosubstrate binding site; other site
699034008629	catalytic site [active]
699034008630	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
699034008631	substrate binding site [chemical binding]; other site
699034008632	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
699034008633	active site
699034008634	catalytic residues [active]
699034008635	metal binding site [ion binding]; metal-binding site
699034008636	Primosomal protein N' (replication factor Y) - superfamily II helicase [DNA replication, recombination, and repair]; Region: PriA; COG1198
699034008637	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
699034008638	ATP binding site [chemical binding]; other site
699034008639	putative Mg++ binding site [ion binding]; other site
699034008640	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
699034008641	nucleotide binding region [chemical binding]; other site
699034008642	ATP-binding site [chemical binding]; other site
699034008643	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase; Validated; Region: PRK05579
699034008644	Flavoprotein; Region: Flavoprotein; pfam02441
699034008645	DNA / pantothenate metabolism flavoprotein; Region: DFP; pfam04127
699034008646	DNA-directed RNA polymerase subunit omega; Reviewed; Region: rpoZ; PRK00392
699034008647	Guanylate kinase; Region: Guanylate_kin; pfam00625
699034008648	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
699034008649	catalytic site [active]
699034008650	G-X2-G-X-G-K; other site
699034008651	hypothetical protein; Provisional; Region: PRK11820
699034008652	YicC-like family, N-terminal region; Region: YicC_N; pfam03755
699034008653	Domain of unknown function (DUF1732); Region: DUF1732; pfam08340
699034008654	diaminopimelate epimerase; Provisional; Region: dapF; PRK00450
699034008655	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
699034008656	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
699034008657	Low-specificity threonine aldolase (TA). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I).  TA catalyzes the conversion of L-threonine or L-allo-threonine to glycine and acetaldehyde in a...; Region: TA_like; cd06502
699034008658	Beta-eliminating lyase; Region: Beta_elim_lyase; pfam01212
699034008659	tetramer interface [polypeptide binding]; other site
699034008660	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034008661	catalytic residue [active]
699034008662	Fibronectin-binding protein A N-terminus (FbpA); Region: FbpA; pfam05833
699034008663	Formamidopyrimidine-DNA glycosylase H2TH domain; Region: H2TH; pfam06831
699034008664	Domain of unknown function (DUF814); Region: DUF814; pfam05670
699034008665	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
699034008666	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
699034008667	ABC transporter; Region: ABC_tran_2; pfam12848
699034008668	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
699034008669	Xanthine/uracil permeases [Nucleotide transport and metabolism]; Region: UraA; COG2233
699034008670	Sulfate transporter family; Region: Sulfate_transp; cl19250
699034008671	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
699034008672	active site
699034008673	pseudouridine synthase, RluA family; Region: rluA_subfam; TIGR00005
699034008674	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
699034008675	RNA binding surface [nucleotide binding]; other site
699034008676	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
699034008677	active site
699034008678	lipoprotein signal peptidase; Provisional; Region: PRK14768
699034008679	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
699034008680	Catalytic NodB homology domain of rhizobial NodB-like proteins; Region: CE4_NodB_like_6s_7s; cd10917
699034008681	NodB motif; other site
699034008682	active site
699034008683	catalytic site [active]
699034008684	metal binding site [ion binding]; metal-binding site
699034008685	Prokaryotic dksA/traR C4-type zinc finger; Region: zf-dskA_traR; cl00755
699034008686	Carbon starvation protein, predicted membrane protein [Signal transduction mechanisms]; Region: CstA; COG1966
699034008687	Carbon starvation protein CstA; Region: CstA; pfam02554
699034008688	C-terminal domain on CstA (DUF4161); Region: DUF4161; pfam13722
699034008689	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
699034008690	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034008691	active site
699034008692	phosphorylation site [posttranslational modification]
699034008693	intermolecular recognition site; other site
699034008694	dimerization interface [polypeptide binding]; other site
699034008695	LytTr DNA-binding domain; Region: LytTR; smart00850
699034008696	Putative regulator of cell autolysis [Signal transduction mechanisms]; Region: LytS; COG3275
699034008697	5TMR of 5TMR-LYT; Region: 5TM-5TMR_LYT; pfam07694
699034008698	Histidine kinase; Region: His_kinase; pfam06580
699034008699	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034008700	ATP binding site [chemical binding]; other site
699034008701	Mg2+ binding site [ion binding]; other site
699034008702	G-X-G motif; other site
699034008703	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cl19078
699034008704	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
699034008705	LytTr DNA-binding domain; Region: LytTR; smart00850
699034008706	VIP2; A family of actin-ADP-ribosylating toxin. A member of the Bacillus-prodiced vegetative insecticidal proteins (VIPs) possesses high specificity against the major insect pest, corn rootworms, and belongs to a classs of binary toxins and regulators of...; Region: VIP2; cl00173
699034008707	VIP2; A family of actin-ADP-ribosylating toxin. A member of the Bacillus-prodiced vegetative insecticidal proteins (VIPs) possesses high specificity against the major insect pest, corn rootworms, and belongs to a classs of binary toxins and regulators of...; Region: VIP2; cd00233
699034008708	active site
699034008709	conformational flexibility of ligand binding pocket; other site
699034008710	ADP-ribosylating toxin turn-turn motif; other site
699034008711	domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins; Region: PA14; smart00758
699034008712	Clostridial binary toxin B/anthrax toxin PA; Region: Binary_toxB; pfam03495
699034008713	tryptophanyl-tRNA synthetase; Reviewed; Region: PRK00927
699034008714	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
699034008715	active site
699034008716	HIGH motif; other site
699034008717	dimer interface [polypeptide binding]; other site
699034008718	KMSKS motif; other site
699034008719	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Validated; Region: PRK05584
699034008720	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
699034008721	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
699034008722	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
699034008723	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
699034008724	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
699034008725	active site
699034008726	EDD domain protein, DegV family; Region: DegV; TIGR00762
699034008727	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
699034008728	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
699034008729	Uncharacterized conserved protein [Function unknown]; Region: COG1284
699034008730	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
699034008731	Uncharacterized BCR, YitT family COG1284; Region: DUF161; pfam02588
699034008732	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
699034008733	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
699034008734	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
699034008735	Probable transposase; Region: OrfB_IS605; pfam01385
699034008736	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
699034008737	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK06039
699034008738	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
699034008739	active site
699034008740	HIGH motif; other site
699034008741	nucleotide binding site [chemical binding]; other site
699034008742	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
699034008743	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
699034008744	active site
699034008745	KMSKS motif; other site
699034008746	Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_ABEc; cd07961
699034008747	tRNA binding surface [nucleotide binding]; other site
699034008748	anticodon binding site; other site
699034008749	DivIVA protein; Region: DivIVA; pfam05103
699034008750	Cell division initiation protein [Cell division and chromosome partitioning]; Region: DivIVA; COG3599
699034008751	Uncharacterized conserved protein, contains S4-like domain [Function unknown]; Region: COG2302
699034008752	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
699034008753	RNA binding surface [nucleotide binding]; other site
699034008754	YGGT family; Region: YGGT; pfam02325
699034008755	Protein of unknown function (DUF552); Region: DUF552; cl00775
699034008756	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes, YBL036c-like proteins; Region: PLPDE_III_YBL036c_like; cd00635
699034008757	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
699034008758	catalytic residue [active]
699034008759	HlyD family secretion protein; Region: HlyD_2; pfam12700
699034008760	Phosphotransferase system, EIIC; Region: PTS_EIIC; cl19164
699034008761	Uncharacterized proteins with similarity to Ribonucleotide reductase and Pyruvate formate lyase; Region: RNR_PFL_like_DUF711; cd08025
699034008762	ACT domain proteins similar to the yet uncharacterized Streptococcus pneumoniae ACT domain protein; Region: ACT_1ZPV; cd04872
699034008763	Stage IV sporulation protein A (spore_IV_A); Region: Spore_IV_A; pfam09547
699034008764	Rat sarcoma (Ras)-like superfamily of small guanosine triphosphatases (GTPases); Region: Ras_like_GTPase; cd00882
699034008765	G1 box; other site
699034008766	GTP/Mg2+ binding site [chemical binding]; other site
699034008767	G2 box; other site
699034008768	Switch I region; other site
699034008769	G3 box; other site
699034008770	Switch II region; other site
699034008771	Major Facilitator Superfamily; Region: MFS_1; pfam07690
699034008772	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
699034008773	putative substrate translocation pore; other site
699034008774	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
699034008775	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
699034008776	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
699034008777	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
699034008778	A family including aminopeptidase P, aminopeptidase M, and prolidase. Also known as metallopeptidase family M24. This family of enzymes is able to cleave amido-, imido- and amidino-containing bonds. Members exibit relatively narrow substrate specificity...; Region: APP_MetAP; cl00279
699034008779	active site
699034008780	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
699034008781	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
699034008782	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase; Validated; Region: gpsA; PRK00094
699034008783	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
699034008784	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
699034008785	putative glycerol-3-phosphate acyltransferase PlsY; Provisional; Region: PRK00220
699034008786	GTP-binding protein Der; Reviewed; Region: PRK00093
699034008787	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
699034008788	G1 box; other site
699034008789	GTP/Mg2+ binding site [chemical binding]; other site
699034008790	Switch I region; other site
699034008791	G2 box; other site
699034008792	Switch II region; other site
699034008793	G3 box; other site
699034008794	G4 box; other site
699034008795	G5 box; other site
699034008796	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
699034008797	G1 box; other site
699034008798	GTP/Mg2+ binding site [chemical binding]; other site
699034008799	Switch I region; other site
699034008800	G2 box; other site
699034008801	G3 box; other site
699034008802	Switch II region; other site
699034008803	G4 box; other site
699034008804	G5 box; other site
699034008805	KH-domain-like of EngA bacterial GTPase enzymes, C-terminal; Region: KH_dom-like; pfam14714
699034008806	putative FeS-containing Cyanobacterial-specific oxidoreductase; Region: cyano_FeS_chp; TIGR03279
699034008807	PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated; Region: PDZ; cl00117
699034008808	Protein of unknown function (DUF512); Region: DUF512; pfam04459
699034008809	YIEGIA protein; Region: YIEGIA; pfam14045
699034008810	YIEGIA protein; Region: YIEGIA; pfam14045
699034008811	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
699034008812	dimerization interface [polypeptide binding]; other site
699034008813	phosphate regulon sensor kinase PhoR; Region: phoR_proteo; TIGR02966
699034008814	PAS domain; Region: PAS; smart00091
699034008815	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034008816	dimer interface [polypeptide binding]; other site
699034008817	phosphorylation site [posttranslational modification]
699034008818	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034008819	ATP binding site [chemical binding]; other site
699034008820	Mg2+ binding site [ion binding]; other site
699034008821	G-X-G motif; other site
699034008822	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034008823	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034008824	active site
699034008825	phosphorylation site [posttranslational modification]
699034008826	intermolecular recognition site; other site
699034008827	dimerization interface [polypeptide binding]; other site
699034008828	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034008829	DNA binding site [nucleotide binding]
699034008830	Multi-copper polyphenol oxidoreductase laccase; Region: Cu-oxidase_4; pfam02578
699034008831	transcriptional regulator NrdR; Validated; Region: nrdR; PRK00464
699034008832	ATP cone domain; Region: ATP-cone; pfam03477
699034008833	Protein implicated in RNA metabolism, contains PRC-barrel domain [General    function prediction only]; Region: COG1873; cl17889
699034008834	sporulation sigma factor SigG; Reviewed; Region: PRK08215
699034008835	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
699034008836	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
699034008837	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
699034008838	DNA binding residues [nucleotide binding]
699034008839	sporulation sigma factor SigE; Reviewed; Region: PRK08301
699034008840	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
699034008841	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
699034008842	DNA binding residues [nucleotide binding]
699034008843	Sporulation factor SpoIIGA; Region: Peptidase_U4; pfam03419
699034008844	ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism]; Region: UgpB; COG1653
699034008845	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; pfam01547
699034008846	cell division protein FtsZ; Validated; Region: PRK09330
699034008847	FtsZ is a GTPase that is similar to the eukaryotic tubulins and is essential for cell division in prokaryotes.  FtsZ is capable of polymerizing in a GTP-driven process into structures similar to those formed by tubulin. FtsZ forms a ring-shaped septum at...; Region: FtsZ_type1; cd02201
699034008848	nucleotide binding site [chemical binding]; other site
699034008849	SulA interaction site; other site
699034008850	Protein of unknown function (DUF1290); Region: DUF1290; pfam06947
699034008851	Bacterial protein of unknown function (DUF881); Region: DUF881; pfam05949
699034008852	Bacterial protein of unknown function (DUF881); Region: DUF881; pfam05949
699034008853	POTRA domain, FtsQ-type; Region: POTRA_1; pfam08478
699034008854	undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase; Provisional; Region: murG; PRK00726
699034008855	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
699034008856	active site
699034008857	homodimer interface [polypeptide binding]; other site
699034008858	Cell cycle protein; Region: FTSW_RODA_SPOVE; cl00511
699034008859	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK14106
699034008860	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
699034008861	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
699034008862	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
699034008863	Mg++ binding site [ion binding]; other site
699034008864	putative catalytic motif [active]
699034008865	putative substrate binding site [chemical binding]; other site
699034008866	UDP-N-acetylmuramyl pentapeptide synthase [Cell envelope biogenesis, outer membrane]; Region: MurF; COG0770
699034008867	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
699034008868	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
699034008869	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
699034008870	stage V sporulation protein D; Region: spoVD_pbp; TIGR02214
699034008871	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
699034008872	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
699034008873	PASTA domain of PBP2x-like proteins, first repeat. Penicillin-binding proteins (PBPs) are the major targets for beta-lactam antibiotics, like penicillins and cephalosporins. Beta-lactam antibiotics specifically inhibit transpeptidase activity by...; Region: PASTA_Pbp2x-like_1; cd06576
699034008874	16S rRNA m(4)C1402 methyltranserfase; Provisional; Region: PRK00050
699034008875	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK12437
699034008876	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
699034008877	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
699034008878	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
699034008879	Predicted Zn-dependent peptidases [General function prediction only]; Region: PqqL; COG0612
699034008880	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
699034008881	GTP-binding protein YchF; Reviewed; Region: PRK09601
699034008882	YchF GTPase; Region: YchF; cd01900
699034008883	G1 box; other site
699034008884	GTP/Mg2+ binding site [chemical binding]; other site
699034008885	Switch I region; other site
699034008886	G2 box; other site
699034008887	Switch II region; other site
699034008888	G3 box; other site
699034008889	G4 box; other site
699034008890	G5 box; other site
699034008891	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
699034008892	Cache domain; Region: Cache_1; pfam02743
699034008893	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
699034008894	metal binding site [ion binding]; metal-binding site
699034008895	active site
699034008896	I-site; other site
699034008897	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
699034008898	UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Provisional; Region: murE; PRK00139
699034008899	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
699034008900	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
699034008901	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
699034008902	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
699034008903	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
699034008904	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
699034008905	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
699034008906	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
699034008907	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
699034008908	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
699034008909	active site turn [active]
699034008910	phosphorylation site [posttranslational modification]
699034008911	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
699034008912	HPr interaction site; other site
699034008913	glycerol kinase (GK) interaction site [polypeptide binding]; other site
699034008914	active site
699034008915	phosphorylation site [posttranslational modification]
699034008916	transcriptional antiterminator BglG; Provisional; Region: PRK09772
699034008917	CAT RNA binding domain; Region: CAT_RBD; smart01061
699034008918	PRD domain; Region: PRD; pfam00874
699034008919	PRD domain; Region: PRD; pfam00874
699034008920	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
699034008921	dipeptide transporter ATP-binding subunit; Provisional; Region: dppF; PRK11308
699034008922	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
699034008923	Walker A/P-loop; other site
699034008924	ATP binding site [chemical binding]; other site
699034008925	Q-loop/lid; other site
699034008926	ABC transporter signature motif; other site
699034008927	Walker B; other site
699034008928	D-loop; other site
699034008929	H-loop/switch region; other site
699034008930	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
699034008931	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
699034008932	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
699034008933	Walker A/P-loop; other site
699034008934	ATP binding site [chemical binding]; other site
699034008935	Q-loop/lid; other site
699034008936	ABC transporter signature motif; other site
699034008937	Walker B; other site
699034008938	D-loop; other site
699034008939	H-loop/switch region; other site
699034008940	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
699034008941	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
699034008942	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cd00995
699034008943	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
699034008944	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034008945	dimer interface [polypeptide binding]; other site
699034008946	conserved gate region; other site
699034008947	putative PBP binding loops; other site
699034008948	ABC-ATPase subunit interface; other site
699034008949	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
699034008950	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034008951	dimer interface [polypeptide binding]; other site
699034008952	conserved gate region; other site
699034008953	putative PBP binding loops; other site
699034008954	ABC-ATPase subunit interface; other site
699034008955	Transcriptional regulator [Transcription]; Region: LysR; COG0583
699034008956	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
699034008957	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
699034008958	dimerization interface [polypeptide binding]; other site
699034008959	putative acyltransferase; Provisional; Region: PRK05790
699034008960	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
699034008961	dimer interface [polypeptide binding]; other site
699034008962	active site
699034008963	Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit [Lipid metabolism]; Region: AtoD; COG1788
699034008964	Coenzyme A transferase; Region: CoA_trans; cl17247
699034008965	3-hydroxybutyrate dehydrogenase; Provisional; Region: PRK12429
699034008966	Rossmann-fold NAD(P)(+)-binding proteins; Region: NADB_Rossmann; cl09931
699034008967	NAD(P) binding site [chemical binding]; other site
699034008968	active site
699034008969	H+/gluconate symporter and related permeases [Carbohydrate transport and metabolism / Amino acid transport and metabolism]; Region: GntT; COG2610
699034008970	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
699034008971	Rad52/22 family double-strand break repair protein; Region: Rad52_Rad22; cl01936
699034008972	Uncharacterized protein with SCP/PR1 domains [Function unknown]; Region: COG2340
699034008973	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
699034008974	pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric; Region: pyruv_ox_red; TIGR02176
699034008975	Pyrimidine (PYR) binding domain of pyruvate ferredoxin oxidoreductase (PFOR), indolepyruvate ferredoxin oxidoreductase alpha subunit (IOR-alpha), and related proteins; Region: TPP_PYR_PFOR_IOR-alpha_like; cd07034
699034008976	dimer interface [polypeptide binding]; other site
699034008977	PYR/PP interface [polypeptide binding]; other site
699034008978	TPP binding site [chemical binding]; other site
699034008979	substrate binding site [chemical binding]; other site
699034008980	Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit [Energy production and conversion]; Region: PorG; COG1014
699034008981	Domain of unknown function; Region: EKR; pfam10371
699034008982	4Fe-4S binding domain; Region: Fer4_6; pfam12837
699034008983	Thiamine pyrophosphate (TPP family), PFOR_PNO subfamily, TPP-binding module; composed of proteins similar to the single subunit pyruvate ferredoxin oxidoreductase (PFOR) of Desulfovibrio Africanus, present in bacteria and amitochondriate eukaryotes. This...; Region: TPP_PFOR_PNO; cd03377
699034008984	TPP-binding site [chemical binding]; other site
699034008985	dimer interface [polypeptide binding]; other site
699034008986	propanediol utilization phosphotransacylase; Provisional; Region: PRK15070
699034008987	Propanediol utilisation protein PduL; Region: PduL; pfam06130
699034008988	Propanediol utilisation protein PduL; Region: PduL; pfam06130
699034008989	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
699034008990	GAF domain; Region: GAF_2; pfam13185
699034008991	GAF domain; Region: GAF_3; pfam13492
699034008992	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
699034008993	Peptidase Gluzincin family (thermolysin-like proteinases, TLPs) includes peptidases M1, M2, M3, M4, M13, M32 and M36 (fungalysins); Region: GluZincin; cl14813
699034008994	Small, acid-soluble spore proteins, alpha/beta type; Region: SASP; pfam00269
699034008995	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
699034008996	HI0933-like protein; Region: HI0933_like; pfam03486
699034008997	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
699034008998	PAP2_like proteins, a super-family of histidine phosphatases and vanadium haloperoxidases, includes type 2 phosphatidic acid phosphatase or lipid phosphate phosphatase (LPP), Glucose-6-phosphatase, Phosphatidylglycerophosphatase B and bacterial acid...; Region: PAP2_like; cl00474
699034008999	Membrane-associated phospholipid phosphatase [Lipid metabolism]; Region: PgpB; COG0671
699034009000	active site
699034009001	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
699034009002	active site
699034009003	Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase [Amino acid transport and metabolism]; Region: HisC; COG0079
699034009004	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
699034009005	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034009006	homodimer interface [polypeptide binding]; other site
699034009007	catalytic residue [active]
699034009008	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
699034009009	Protein of unknown function (DUF1232); Region: DUF1232; cl01318
699034009010	asparagine synthetase AsnA; Provisional; Region: PRK05425
699034009011	motif 1; other site
699034009012	dimer interface [polypeptide binding]; other site
699034009013	active site
699034009014	motif 2; other site
699034009015	motif 3; other site
699034009016	putative C-S lyase; Region: C_S_lyase_PatB; TIGR04350
699034009017	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
699034009018	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034009019	homodimer interface [polypeptide binding]; other site
699034009020	catalytic residue [active]
699034009021	M20 Peptidase Aminoacylase 1 amhX_like subfamily; Region: M20_Acy1_amhX_like; cd08018
699034009022	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
699034009023	metal binding site [ion binding]; metal-binding site
699034009024	putative dimer interface [polypeptide binding]; other site
699034009025	hypothetical protein; Provisional; Region: PRK10519
699034009026	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
699034009027	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034009028	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
699034009029	Walker A motif; other site
699034009030	ATP binding site [chemical binding]; other site
699034009031	Walker B motif; other site
699034009032	arginine finger; other site
699034009033	Protein of unknown function (DUF3798); Region: DUF3798; pfam12683
699034009034	Branched-chain amino acid transport protein; Region: Branch_AA_trans; cl00547
699034009035	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
699034009036	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
699034009037	Xanthine/uracil/vitamin C permease [Nucleotide transport and    metabolism]; Region: COG2252
699034009038	Sulfate transporter family; Region: Sulfate_transp; cl19250
699034009039	N-ethylammeline chlorohydrolase; Provisional; Region: PRK07228
699034009040	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
699034009041	active site
699034009042	putative substrate binding pocket [chemical binding]; other site
699034009043	The HIRAN protein (HIP116, Rad5p N-terminal) is found in the N-terminal regions of the SWI2/SNF2 proteins typified by HIP116 and Rad5p; Region: HIRAN; smart00910
699034009044	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
699034009045	Major Facilitator Superfamily; Region: MFS_1; pfam07690
699034009046	putative substrate translocation pore; other site
699034009047	shikimate 5-dehydrogenase; Provisional; Region: PRK12548
699034009048	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
699034009049	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
699034009050	shikimate binding site; other site
699034009051	NAD(P) binding site [chemical binding]; other site
699034009052	mycofactocin system FadH/OYE family oxidoreductase 2; Region: mycofact_OYE_2; TIGR03997
699034009053	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN_family; cd02803
699034009054	active site
699034009055	FMN binding site [chemical binding]; other site
699034009056	substrate binding site [chemical binding]; other site
699034009057	putative catalytic residue [active]
699034009058	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
699034009059	Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism]; Region: IolE; COG1082
699034009060	Xylose isomerase-like TIM barrel; Region: AP_endonuc_2; pfam01261
699034009061	Transcriptional regulator [Transcription]; Region: LysR; COG0583
699034009062	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
699034009063	The substrate binding domain of LysR-type transcriptional regulator GltC, which activates gltA expression of glutamate synthase operon, contains type 2 periplasmic binding fold; Region: PBP2_GltC_like; cd08434
699034009064	putative dimerization interface [polypeptide binding]; other site
699034009065	Protein of unknown function (DUF3800); Region: DUF3800; pfam12686
699034009066	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
699034009067	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
699034009068	FOG: Glucan-binding domain (YG repeat) [General function prediction only]; Region: COG5263
699034009069	Putative cell wall binding repeat; Region: CW_binding_1; pfam01473
699034009070	Putative cell wall binding repeat; Region: CW_binding_1; pfam01473
699034009071	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009072	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009073	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009074	UDP-glucose 4 epimerase, subgroup 1, extended (e) SDRs; Region: UDP_G4E_1_SDR_e; cd05247
699034009075	UDP-glucose 4-epimerase; Region: PLN02240
699034009076	NAD binding site [chemical binding]; other site
699034009077	homodimer interface [polypeptide binding]; other site
699034009078	active site
699034009079	substrate binding site [chemical binding]; other site
699034009080	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
699034009081	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
699034009082	active site
699034009083	tetramer interface; other site
699034009084	preprotein translocase subunit SecA; Reviewed; Region: secA; PRK12903
699034009085	Sporulation related domain; Region: SPOR; pfam05036
699034009086	Sortase B (SrtB) or subfamily-2 sortases are membrane cysteine transpeptidases found in gram-positive bacteria that anchor surface proteins to peptidoglycans of the bacterial cell wall envelope. This involves a transpeptidation reaction in which the...; Region: Sortase_B_2; cd05826
699034009087	active site
699034009088	catalytic site [active]
699034009089	potential RNA of insufficient length (23S ribosomal RNA)
699034009090	Catalytic NodB homology domain of Bacillus subtilis polysaccharide deacetylase PdaA, and its bacterial homologs; Region: CE4_BsPdaA_like; cd10948
699034009091	delta-lactam-biosynthetic de-N-acetylase; Region: spore_pdaA; TIGR02884
699034009092	NodB motif; other site
699034009093	active site
699034009094	catalytic site [active]
699034009095	Cd binding site [ion binding]; other site
699034009096	TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism]; Region: DctQ; cl17274
699034009097	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034009098	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
699034009099	dimerization interface [polypeptide binding]; other site
699034009100	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034009101	dimer interface [polypeptide binding]; other site
699034009102	phosphorylation site [posttranslational modification]
699034009103	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034009104	ATP binding site [chemical binding]; other site
699034009105	Mg2+ binding site [ion binding]; other site
699034009106	G-X-G motif; other site
699034009107	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034009108	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034009109	active site
699034009110	phosphorylation site [posttranslational modification]
699034009111	intermolecular recognition site; other site
699034009112	dimerization interface [polypeptide binding]; other site
699034009113	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034009114	DNA binding site [nucleotide binding]
699034009115	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
699034009116	delta-lactam-biosynthetic de-N-acetylase; Region: spore_pdaA; TIGR02884
699034009117	Catalytic NodB homology domain of uncharacterized bacterial polysaccharide deacetylases; Region: CE4_NodB_like_3; cd10959
699034009118	NodB motif; other site
699034009119	putative active site [active]
699034009120	putative catalytic site [active]
699034009121	putative Zn binding site [ion binding]; other site
699034009122	diacylglycerol glucosyltransferase; Provisional; Region: PRK13609
699034009123	Monogalactosyldiacylglycerol (MGDG) synthase; Region: MGDG_synth; pfam06925
699034009124	Glycosyltransferase family 28 C-terminal domain; Region: Glyco_tran_28_C; cl19139
699034009125	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
699034009126	dimer interface [polypeptide binding]; other site
699034009127	active site
699034009128	glycine-pyridoxal phosphate binding site [chemical binding]; other site
699034009129	folate binding site [chemical binding]; other site
699034009130	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
699034009131	Uncharacterized conserved protein [Function unknown]; Region: COG2966
699034009132	Protein of unknown function (DUF1212); Region: DUF1212; pfam06738
699034009133	Protein of unknown function (DUF3815); Region: DUF3815; pfam12821
699034009134	Positive regulator of sigma(E), RseC/MucC; Region: RseC_MucC; pfam04246
699034009135	Transcriptional regulators CsoR (copper-sensitive operon repressor), RcnR, and FrmR, and related domains; this domain superfamily was previously known as DUF156; Region: CsoR-like_DUF156; cd10148
699034009136	putative homodimer interface [polypeptide binding]; other site
699034009137	putative homotetramer interface [polypeptide binding]; other site
699034009138	putative allosteric switch controlling residues; other site
699034009139	putative metal binding site [ion binding]; other site
699034009140	putative homodimer-homodimer interface [polypeptide binding]; other site
699034009141	PAS domain; Region: PAS; smart00091
699034009142	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034009143	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
699034009144	Walker A motif; other site
699034009145	ATP binding site [chemical binding]; other site
699034009146	Walker B motif; other site
699034009147	arginine finger; other site
699034009148	putative C-S lyase; Region: C_S_lyase_PatB; TIGR04350
699034009149	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
699034009150	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034009151	homodimer interface [polypeptide binding]; other site
699034009152	catalytic residue [active]
699034009153	Na+/H+ antiporter NhaC; Region: antiport_nhaC; TIGR00931
699034009154	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
699034009155	Na+/H+ antiporter family; Region: Na_H_antiporter; pfam03553
699034009156	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009157	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009158	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009159	Bacterial SH3 domain; Region: SH3_3; pfam08239
699034009160	Bacterial SH3 domain; Region: SH3_3; pfam08239
699034009161	Transcriptional regulator [Transcription]; Region: LysR; COG0583
699034009162	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
699034009163	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
699034009164	dimerization interface [polypeptide binding]; other site
699034009165	Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases); Region: nitrilase_6; cd07584
699034009166	putative active site [active]
699034009167	catalytic triad [active]
699034009168	putative dimer interface [polypeptide binding]; other site
699034009169	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
699034009170	Na binding site [ion binding]; other site
699034009171	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
699034009172	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
699034009173	dimer interface [polypeptide binding]; other site
699034009174	anticodon binding site; other site
699034009175	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
699034009176	homodimer interface [polypeptide binding]; other site
699034009177	motif 1; other site
699034009178	active site
699034009179	motif 2; other site
699034009180	GAD domain; Region: GAD; pfam02938
699034009181	motif 3; other site
699034009182	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
699034009183	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
699034009184	dimer interface [polypeptide binding]; other site
699034009185	motif 1; other site
699034009186	active site
699034009187	motif 2; other site
699034009188	motif 3; other site
699034009189	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
699034009190	anticodon binding site; other site
699034009191	coproporphyrinogen III oxidase; Provisional; Region: PRK08207
699034009192	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
699034009193	FeS/SAM binding site; other site
699034009194	Zn-dependent hydrolases, including glyoxylases [General function prediction only]; Region: GloB; COG0491
699034009195	D-Tyrosyl-tRNAtyr deacylases; a class of tRNA-dependent hydrolases which are capable of hydrolyzing the ester bond of D-Tyrosyl-tRNA reducing the level of cellular D-Tyrosine while recycling the peptidyl-tRNA; found in bacteria and in eukaryotes but not...; Region: Dtyr_deacylase; cd00563
699034009196	putative active site [active]
699034009197	dimerization interface [polypeptide binding]; other site
699034009198	putative tRNAtyr binding site [nucleotide binding]; other site
699034009199	Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription]; Region: SpoT; COG0317
699034009200	Metal dependent phosphohydrolases with conserved 'HD' motif; Region: HDc; cd00077
699034009201	Zn2+ binding site [ion binding]; other site
699034009202	Mg2+ binding site [ion binding]; other site
699034009203	Nucleotidyltransferase (NT) domain of RelA- and SpoT-like ppGpp synthetases and hydrolases; Region: NT_Rel-Spo_like; cd05399
699034009204	synthetase active site [active]
699034009205	NTP binding site [chemical binding]; other site
699034009206	metal binding site [ion binding]; metal-binding site
699034009207	TGS_RelA_SpoT: The RelA (SpoT) protein, also referred to as ppGpp hydrolase/synthetase, is a ribosome-associated protein that is activated during amino acid starvation and thought to mediate the stringent response. RelA contains a TGS domain, named after...; Region: TGS_RelA_SpoT; cd01668
699034009208	ACT  domain found C-terminal of the RelA/SpoT domains; Region: ACT_RelA-SpoT; cd04876
699034009209	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
699034009210	active site
699034009211	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
699034009212	DHH family; Region: DHH; pfam01368
699034009213	DHHA1 domain; Region: DHHA1; pfam02272
699034009214	Predicted unusual protein kinase [General function prediction only]; Region: AarF; COG0661
699034009215	2-polyprenylphenol 6-hydroxylase; Region: UbiB; TIGR01982
699034009216	active site
699034009217	ATP binding site [chemical binding]; other site
699034009218	Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily [General function prediction only]; Region: PaaY; COG0663
699034009219	Gamma carbonic anhydrase-like: This family is composed of gamma carbonic anhydrase (CA), Ferripyochelin Binding Protein (FBP), E. coli paaY protein, and similar proteins. CAs are zinc-containing enzymes that catalyze the reversible hydration of carbon...; Region: LbH_gamma_CA_like; cd04645
699034009220	trimer interface [polypeptide binding]; other site
699034009221	putative metal binding site [ion binding]; other site
699034009222	SCIFF radical SAM maturase; Region: rSAM_six_Cys; TIGR03974
699034009223	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
699034009224	FeS/SAM binding site; other site
699034009225	radical SAM additional 4Fe4S-binding SPASM domain; Region: rSAM_more_4Fe4S; TIGR04085
699034009226	Staphylococcal AgrD protein; Region: AgrD; cl05477
699034009227	Accessory gene regulator B; Region: AgrB; pfam04647
699034009228	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034009229	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034009230	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034009231	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034009232	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034009233	Domain of unknown function (DUF4116); Region: DUF4116; pfam13475
699034009234	PEP-utilizing enzyme, N-terminal; Region: PEP-utilizers_N; pfam05524
699034009235	Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) [Carbohydrate transport and metabolism]; Region: PtsA; COG1080
699034009236	PEP-utilizing enzyme, mobile domain; Region: PEP-utilizers; pfam00391
699034009237	PEP-utilizing enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
699034009238	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
699034009239	dimerization domain swap beta strand [polypeptide binding]; other site
699034009240	regulatory protein interface [polypeptide binding]; other site
699034009241	active site
699034009242	regulatory phosphorylation site [posttranslational modification]; other site
699034009243	Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only]; Region: RssA; COG1752
699034009244	Hypothetical patatin similar to Z1214 protein of Escherichia coli; Region: Pat_hypo_Ecoli_Z1214_like; cd07209
699034009245	active site
699034009246	nucleophile elbow; other site
699034009247	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
699034009248	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
699034009249	S-adenosylmethionine binding site [chemical binding]; other site
699034009250	Eco57I restriction-modification methylase; Region: Eco57I; pfam07669
699034009251	TaqI-like C-terminal specificity domain; Region: TaqI_C; pfam12950
699034009252	Transcriptional regulator; Region: Rrf2; cl17282
699034009253	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
699034009254	nucleotidyl binding site; other site
699034009255	metal binding site [ion binding]; metal-binding site
699034009256	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
699034009257	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
699034009258	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
699034009259	active site
699034009260	metal binding site [ion binding]; metal-binding site
699034009261	Cis (Z)-Isoprenyl Diphosphate Synthases; Region: Cis_IPPS; cd00475
699034009262	active site
699034009263	dimer interface [polypeptide binding]; other site
699034009264	Domain of unknown function (DUF4358); Region: DUF4358; pfam14270
699034009265	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
699034009266	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
699034009267	active site
699034009268	motif I; other site
699034009269	motif II; other site
699034009270	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
699034009271	Transcriptional regulator [Transcription]; Region: LytR; COG1316
699034009272	Transcriptional regulator [Transcription]; Region: LytR; COG1316
699034009273	Alpha amylase catalytic domain family; Region: AmyAc_family; cl07893
699034009274	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009275	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009276	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009277	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
699034009278	Bacterial SH3 domain; Region: SH3_3; pfam08239
699034009279	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
699034009280	NlpC/P60 family; Region: NLPC_P60; pfam00877
699034009281	Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: COG1086
699034009282	CoA binding domain; Region: CoA_binding; cl17356
699034009283	UDP-Glcnac (UDP-linked N-acetylglucosamine) inverting 4,6-dehydratase, extended (e) SDRs; Region: UDP_invert_4-6DH_SDR_e; cd05237
699034009284	NAD(P) binding site [chemical binding]; other site
699034009285	homodimer interface [polypeptide binding]; other site
699034009286	substrate binding site [chemical binding]; other site
699034009287	active site
699034009288	This family is most closely related to the GT1 family of glycosyltransferases. wlbH in Bordetella parapertussis has been shown to be required for the biosynthesis of a trisaccharide that, when attached to the B. pertussis lipopolysaccharide (LPS) core; Region: GT1_wlbH_like; cd03798
699034009289	Glycosyltransferase [Cell envelope biogenesis, outer membrane]; Region: RfaG; COG0438
699034009290	Predicted UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]; Region: Ugd; COG1004
699034009291	UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; Region: UDPG_MGDP_dh_N; pfam03721
699034009292	UDP-glucose/GDP-mannose dehydrogenase family, central domain; Region: UDPG_MGDP_dh; pfam00984
699034009293	UDP binding domain; Region: UDPG_MGDP_dh_C; smart00984
699034009294	Glycosyltransferase like family 2; Region: Glyco_tranf_2_3; pfam13641
699034009295	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
699034009296	active site
699034009297	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
699034009298	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
699034009299	active site
699034009300	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
699034009301	Glycosyl transferase family 2; Region: Glycos_transf_2; pfam00535
699034009302	active site
699034009303	Capsule polysaccharide biosynthesis protein; Region: Capsule_synth; cl19502
699034009304	CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase; Region: Glyphos_transf; pfam04464
699034009305	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
699034009306	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cd00761
699034009307	active site
699034009308	Mannosyltransferase OCH1 and related enzymes [Cell envelope biogenesis, outer membrane]; Region: OCH1; COG3774
699034009309	Glycosyltransferase sugar-binding region containing DXD motif; Region: Gly_transf_sug; cl19952
699034009310	Mannose-1-phosphate guanylyltransferase [Cell envelope biogenesis, outer membrane]; Region: {ManC}; COG0836
699034009311	GDP-M1P_Guanylyltransferase catalyzes the formation of GDP-Mannose; Region: GDP-M1P_Guanylyltransferase; cd02509
699034009312	Substrate binding site; other site
699034009313	Cupin domain; Region: Cupin_2; cl17218
699034009314	phosphoglucomutase-2-like protein; Provisional; Region: PTZ00150
699034009315	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
699034009316	active site
699034009317	substrate binding site [chemical binding]; other site
699034009318	metal binding site [ion binding]; metal-binding site
699034009319	Uncharacterized membrane protein, putative virulence factor [General function prediction only]; Region: MviN; COG0728
699034009320	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
699034009321	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009322	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009323	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009324	Bacterial sugar transferase; Region: Bac_transf; pfam02397
699034009325	exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase; Region: EPS_sugtrans; TIGR03025
699034009326	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009327	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009328	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009329	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
699034009330	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
699034009331	active site
699034009332	metal binding site [ion binding]; metal-binding site
699034009333	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4299
699034009334	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009335	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009336	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009337	C1 Peptidase family (MEROPS database nomenclature), also referred to as the papain family; composed of two subfamilies of cysteine peptidases (CPs), C1A (papain) and C1B (bleomycin hydrolase). Papain-like enzymes are mostly endopeptidases with some...; Region: Peptidase_C1; cd02619
699034009338	active site
699034009339	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009340	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009341	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009342	GtrA-like protein; Region: GtrA; pfam04138
699034009343	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009344	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009345	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009346	GlcNAc-PI de-N-acetylase; Region: PIG-L; pfam02585
699034009347	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009348	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009349	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009350	preprotein translocase subunit SecA; Reviewed; Region: PRK12904
699034009351	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
699034009352	ATP binding site [chemical binding]; other site
699034009353	putative Mg++ binding site [ion binding]; other site
699034009354	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
699034009355	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
699034009356	nucleotide binding region [chemical binding]; other site
699034009357	ATP-binding site [chemical binding]; other site
699034009358	SecA Wing and Scaffold domain; Region: SecA_SW; pfam07516
699034009359	Low molecular weight S layer protein N terminal; Region: LMWSLP_N; pfam12211
699034009360	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009361	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009362	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009363	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009364	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009365	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
699034009366	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
699034009367	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009368	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009369	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009370	Bacterial Ig-like domain (group 3); Region: Big_3; pfam07523
699034009371	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
699034009372	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009373	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009374	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009375	Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all...; Region: FN3; cd00063
699034009376	Interdomain contacts; other site
699034009377	Cytokine receptor motif; other site
699034009378	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
699034009379	Peptidase M60-like family; Region: M60-like; cl19940
699034009380	F5/8 type C domain; Region: F5_F8_type_C; pfam00754
699034009381	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009382	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009383	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009384	SCP_bacterial: SCP-like extracellular protein domain, as found in bacteria and archaea. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, and allergen 5...; Region: SCP_bacterial; cd05379
699034009385	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009386	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009387	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034009388	Protein of unknown function (DUF4001); Region: DUF4001; pfam13165
699034009389	Protein of unknown function (DUF3792); Region: DUF3792; pfam12670
699034009390	Preprotein translocase subunit; Region: YajC; pfam02699
699034009391	queuine tRNA-ribosyltransferase; Provisional; Region: tgt; PRK00112
699034009392	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
699034009393	S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional; Region: queA; PRK00147
699034009394	Holliday junction DNA helicase RuvB; Reviewed; Region: ruvB; PRK00080
699034009395	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034009396	Walker A motif; other site
699034009397	ATP binding site [chemical binding]; other site
699034009398	Walker B motif; other site
699034009399	arginine finger; other site
699034009400	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
699034009401	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
699034009402	RuvA N terminal domain; Region: RuvA_N; pfam01330
699034009403	Helix-hairpin-helix domain; Region: HHH_5; pfam14520
699034009404	RuvA, C-terminal domain; Region: RuvA_C; pfam07499
699034009405	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
699034009406	active site
699034009407	putative DNA-binding cleft [nucleotide binding]; other site
699034009408	dimer interface [polypeptide binding]; other site
699034009409	Domain of Unknown Function (DUF1540); Region: DUF1540; pfam07561
699034009410	Domain of Unknown Function (DUF1540); Region: DUF1540; pfam07561
699034009411	Protein of unknown function (DUF1113); Region: DUF1113; pfam06541
699034009412	Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly.  The complex contains two alpha and four beta subunits, the two subunits...; Region: Prefoldin; cl09111
699034009413	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3395
699034009414	GntP family permease; Region: GntP_permease; pfam02447
699034009415	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cl17221
699034009416	tartronate semialdehyde reductase; Provisional; Region: garR; PRK11559
699034009417	NAD binding domain of 6-phosphogluconate dehydrogenase; Region: NAD_binding_2; pfam03446
699034009418	NAD-binding of NADP-dependent 3-hydroxyisobutyrate dehydrogenase; Region: NAD_binding_11; pfam14833
699034009419	Transcriptional regulators [Transcription]; Region: GntR; COG1802
699034009420	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
699034009421	DNA-binding site [nucleotide binding]; DNA binding site
699034009422	FCD domain; Region: FCD; pfam07729
699034009423	L-2-amino-thiazoline-4-carboxylic acid hydrolase; Region: ATC_hydrolase; pfam14196
699034009424	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
699034009425	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
699034009426	ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Region: ABCC_Glucan_exporter_like; cd03254
699034009427	Walker A/P-loop; other site
699034009428	ATP binding site [chemical binding]; other site
699034009429	Q-loop/lid; other site
699034009430	ABC transporter signature motif; other site
699034009431	Walker B; other site
699034009432	D-loop; other site
699034009433	H-loop/switch region; other site
699034009434	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
699034009435	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
699034009436	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034009437	Walker A/P-loop; other site
699034009438	ATP binding site [chemical binding]; other site
699034009439	Q-loop/lid; other site
699034009440	ABC transporter signature motif; other site
699034009441	Walker B; other site
699034009442	D-loop; other site
699034009443	H-loop/switch region; other site
699034009444	potential frameshift: common BLAST hit: gi|308175184|ref|YP_003921889.1| oxidoreductase
699034009445	Predicted amino acid aldolase or racemase [Amino acid transport and metabolism]; Region: COG3616
699034009446	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzymes; Region: PLPDE_III; cl00261
699034009447	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
699034009448	catalytic residue [active]
699034009449	putative transposase OrfB; Reviewed; Region: PHA02517
699034009450	HTH-like domain; Region: HTH_21; pfam13276
699034009451	Integrase core domain; Region: rve; pfam00665
699034009452	Integrase core domain; Region: rve_2; pfam13333
699034009453	Homeodomain-like domain; Region: HTH_23; pfam13384
699034009454	hypothetical protein; Provisional; Region: PRK10519
699034009455	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3314
699034009456	Nucleoside recognition; Region: Gate; pfam07670
699034009457	glutamate carboxypeptidase; Reviewed; Region: PRK06133
699034009458	M20 Peptidase Glutamate carboxypeptidase, a periplasmic enzyme; Region: M20_CPDG2; cd03885
699034009459	metal binding site [ion binding]; metal-binding site
699034009460	dimer interface [polypeptide binding]; other site
699034009461	Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592
699034009462	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
699034009463	DNA binding residues [nucleotide binding]
699034009464	dimer interface [polypeptide binding]; other site
699034009465	Protein of unknown function (DUF1648); Region: DUF1648; pfam07853
699034009466	NADPH-dependent FMN reductase; Region: FMN_red; cl00438
699034009467	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
699034009468	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
699034009469	Probable transposase; Region: OrfB_IS605; pfam01385
699034009470	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
699034009471	NADPH-dependent FMN reductase; Region: FMN_red; cl00438
699034009472	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
699034009473	phosphate binding site [ion binding]; other site
699034009474	Transcriptional regulators [Transcription]; Region: MarR; COG1846
699034009475	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
699034009476	aspartate aminotransferase; Provisional; Region: PRK06836
699034009477	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
699034009478	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034009479	homodimer interface [polypeptide binding]; other site
699034009480	catalytic residue [active]
699034009481	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
699034009482	EamA-like transporter family; Region: EamA; pfam00892
699034009483	EamA-like transporter family; Region: EamA; pfam00892
699034009484	Anthrax toxin lethal factor, N- and C-terminal domain; Region: ATLF; pfam07737
699034009485	PPP4R2; Region: PPP4R2; pfam09184
699034009486	Collagen binding domain; Region: Collagen_bind; pfam05737
699034009487	Collagen binding domain; Region: Collagen_bind; pfam05737
699034009488	Cna protein B-type domain; Region: Cna_B; pfam05738
699034009489	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
699034009490	YbaK-like.  The YbaK family of deacylase domains includes the INS amino acid-editing domain of  the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting homologs, YbaK, ProX, and PrdX. The primary function of INS is to hydrolyze...; Region: YbaK_like; cl00022
699034009491	Cation transporter/ATPase, N-terminus; Region: Cation_ATPase_N; pfam00690
699034009492	Cation transport ATPase [Inorganic ion transport and metabolism]; Region: MgtA; COG0474
699034009493	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
699034009494	Putative hydrolase of sodium-potassium ATPase alpha subunit; Region: Hydrolase_like2; pfam13246
699034009495	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
699034009496	Soluble P-type ATPase [General function prediction only]; Region: COG4087
699034009497	Cation transporting ATPase, C-terminus; Region: Cation_ATPase_C; pfam00689
699034009498	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
699034009499	dimer interface [polypeptide binding]; other site
699034009500	active site
699034009501	glycine-pyridoxal phosphate binding site [chemical binding]; other site
699034009502	folate binding site [chemical binding]; other site
699034009503	Putative p-aminobenzoyl-glutamate transporter [Coenzyme metabolism]; Region: AbgT; COG2978
699034009504	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
699034009505	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
699034009506	metal binding site [ion binding]; metal-binding site
699034009507	dimer interface [polypeptide binding]; other site
699034009508	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
699034009509	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
699034009510	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034009511	active site
699034009512	phosphorylation site [posttranslational modification]
699034009513	intermolecular recognition site; other site
699034009514	dimerization interface [polypeptide binding]; other site
699034009515	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
699034009516	Cupin domain; Region: Cupin_2; pfam07883
699034009517	Histidine kinase; Region: His_kinase; pfam06580
699034009518	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034009519	ATP binding site [chemical binding]; other site
699034009520	Mg2+ binding site [ion binding]; other site
699034009521	G-X-G motif; other site
699034009522	seryl-tRNA synthetase; Provisional; Region: PRK05431
699034009523	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
699034009524	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
699034009525	dimer interface [polypeptide binding]; other site
699034009526	active site
699034009527	motif 1; other site
699034009528	motif 2; other site
699034009529	motif 3; other site
699034009530	Predicted metal-dependent hydrolase with the TIM-barrel fold [General function prediction only]; Region: COG1574
699034009531	YtcJ_like metal dependent amidohydrolases. YtcJ is a Bacillus subtilis ORF of unknown function. The Arabidopsis homolog LAF3 has been identified as a factor required for photochrome A signalling; Region: YtcJ_like; cd01300
699034009532	active site
699034009533	Nitrilases, cyanide hydratase (CH)s, and similar proteins (class 1 nitrilases); Region: nitrilases_CHs; cd07564
699034009534	putative active site [active]
699034009535	catalytic triad [active]
699034009536	putative dimer interface [polypeptide binding]; other site
699034009537	Yhdh and yhfp-like putative quinone oxidoreductases; Region: MDR_yhdh_yhfp; cd05280
699034009538	putative quinone oxidoreductase, YhdH/YhfP family; Region: oxido_YhdH; TIGR02823
699034009539	NADP binding site [chemical binding]; other site
699034009540	dimer interface [polypeptide binding]; other site
699034009541	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
699034009542	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
699034009543	dimerization interface [polypeptide binding]; other site
699034009544	putative DNA binding site [nucleotide binding]; other site
699034009545	putative Zn2+ binding site [ion binding]; other site
699034009546	Rubrerythrin [Energy production and conversion]; Region: COG1592
699034009547	Rubrerythrin, ferritin-like diiron-binding domain; Region: Rubrerythrin; cd01041
699034009548	binuclear metal center [ion binding]; other site
699034009549	Rubredoxin, Small Modular nonheme iron binding domain containing a [Fe(SCys)4] center, present in rubrerythrin and nigerythrin and detected either N- or C-terminal to such proteins as flavin reductase, NAD(P)H-nitrite reductase, and...; Region: rubredoxin_SM; cd00729
699034009550	iron binding site [ion binding]; other site
699034009551	Protein of unknown function (DUF4004); Region: DUF4004; pfam13171
699034009552	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
699034009553	phosphonoacetaldehyde hydrolase; Provisional; Region: PRK13478
699034009554	phosphonoacetaldehyde hydrolase; Region: phosphonatase; TIGR01422
699034009555	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
699034009556	motif II; other site
699034009557	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl18945
699034009558	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
699034009559	catalytic residue [active]
699034009560	Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism]; Region: GlpR; COG1349
699034009561	helix_turn_helix, Deoxyribose operon repressor; Region: HTH_DEOR; smart00420
699034009562	DeoR C terminal sensor domain; Region: DeoRC; pfam00455
699034009563	Phosphopantetheine attachment site; Region: PP-binding; cl09936
699034009564	D-alanyl-lipoteichoic acid biosynthesis protein DltB; Region: LTA_dltB; TIGR04091
699034009565	D-alanine--poly(phosphoribitol) ligase subunit 1; Provisional; Region: PRK04813
699034009566	D-alanine:D-alanyl carrier protein ligase (DltA); Region: DltA; cd05945
699034009567	acyl-activating enzyme (AAE) consensus motif; other site
699034009568	AMP binding site [chemical binding]; other site
699034009569	Protein of unknown function (DUF2921); Region: DUF2921; pfam11145
699034009570	D-alanyl-lipoteichoic acid biosynthesis protein DltD; Region: LTA_DltD; TIGR04092
699034009571	DltD central region; Region: DltD_M; pfam04918
699034009572	DltD C-terminal region; Region: DltD_C; pfam04914
699034009573	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
699034009574	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
699034009575	Protein of unknown function (DUF1113); Region: DUF1113; cl19877
699034009576	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
699034009577	beta-phosphoglucomutase family hydrolase; Region: PGMB-YQAB-SF; TIGR02009
699034009578	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
699034009579	motif II; other site
699034009580	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
699034009581	Domain of unknown function DUF21; Region: DUF21; pfam01595
699034009582	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
699034009583	Transporter associated domain; Region: CorC_HlyC; smart01091
699034009584	N-acyl-D-aspartate/D-glutamate deacylase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3653
699034009585	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
699034009586	active site
699034009587	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
699034009588	active site
699034009589	PAS domain; Region: PAS; smart00091
699034009590	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034009591	Walker A motif; other site
699034009592	ATP binding site [chemical binding]; other site
699034009593	Walker B motif; other site
699034009594	arginine finger; other site
699034009595	Putative lysophospholipase; Region: Hydrolase_4; cl19140
699034009596	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
699034009597	Manganese catalase-like protein, ferritin-like diiron-binding domain; Region: Mn_catalase_like; cd07908
699034009598	Ferritin-like domain; Region: Ferritin; pfam00210
699034009599	dinuclear metal binding motif [ion binding]; other site
699034009600	FtsX-like permease family; Region: FtsX; pfam02687
699034009601	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
699034009602	FtsX-like permease family; Region: FtsX; pfam02687
699034009603	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
699034009604	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
699034009605	Walker A/P-loop; other site
699034009606	ATP binding site [chemical binding]; other site
699034009607	Q-loop/lid; other site
699034009608	ABC transporter signature motif; other site
699034009609	Walker B; other site
699034009610	D-loop; other site
699034009611	H-loop/switch region; other site
699034009612	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034009613	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034009614	ATP binding site [chemical binding]; other site
699034009615	Mg2+ binding site [ion binding]; other site
699034009616	G-X-G motif; other site
699034009617	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034009618	DNA-binding transcriptional regulator TorR; Provisional; Region: PRK10766
699034009619	active site
699034009620	phosphorylation site [posttranslational modification]
699034009621	intermolecular recognition site; other site
699034009622	dimerization interface [polypeptide binding]; other site
699034009623	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034009624	DNA binding site [nucleotide binding]
699034009625	Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only]; Region: TldD; COG0312
699034009626	Predicted Zn-dependent proteases and their inactivated homologs [General function prediction only]; Region: TldD; COG0312
699034009627	putative aminophosphonate oxidoreductase; Region: Phn_aa_oxid; TIGR03329
699034009628	FAD dependent oxidoreductase; Region: DAO; pfam01266
699034009629	Propionate catabolism activator; Region: PrpR_N; pfam06506
699034009630	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
699034009631	PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in...; Region: PAS; cd00130
699034009632	putative active site [active]
699034009633	heme pocket [chemical binding]; other site
699034009634	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034009635	Walker A motif; other site
699034009636	ATP binding site [chemical binding]; other site
699034009637	Walker B motif; other site
699034009638	arginine finger; other site
699034009639	Bacterial regulatory protein, Fis family; Region: HTH_8; cl17420
699034009640	2-keto-3-deoxygluconate permease; Provisional; Region: PRK12460
699034009641	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
699034009642	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
699034009643	Class III nucleotidyl cyclases; Region: Nucleotidyl_cyc_III; cl11967
699034009644	nucleotidyl binding site; other site
699034009645	metal binding site [ion binding]; metal-binding site
699034009646	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
699034009647	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
699034009648	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
699034009649	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
699034009650	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
699034009651	Walker A/P-loop; other site
699034009652	ATP binding site [chemical binding]; other site
699034009653	Q-loop/lid; other site
699034009654	ABC transporter signature motif; other site
699034009655	Walker B; other site
699034009656	D-loop; other site
699034009657	H-loop/switch region; other site
699034009658	ABC-type enterobactin transport system, permease component [Inorganic ion transport and metabolism]; Region: FepG; COG4779
699034009659	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
699034009660	ABC-ATPase subunit  interface; other site
699034009661	dimer interface [polypeptide binding]; other site
699034009662	putative PBP binding regions; other site
699034009663	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
699034009664	ABC-ATPase subunit  interface; other site
699034009665	dimer interface [polypeptide binding]; other site
699034009666	putative PBP binding regions; other site
699034009667	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
699034009668	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
699034009669	intersubunit interface [polypeptide binding]; other site
699034009670	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
699034009671	methionine cluster; other site
699034009672	active site
699034009673	phosphorylation site [posttranslational modification]
699034009674	metal binding site [ion binding]; metal-binding site
699034009675	Enterococcus faecalis EF3048 and similar proteins; Region: YdjC_EF3048_like; cd10803
699034009676	putative active site [active]
699034009677	YdjC motif; other site
699034009678	Mg binding site [ion binding]; other site
699034009679	putative homodimer interface [polypeptide binding]; other site
699034009680	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
699034009681	Glycoside Hydrolases Family 4; Phospho-beta-glucosidase; Region: GH4_P_beta_glucosidase; cd05296
699034009682	NAD binding site [chemical binding]; other site
699034009683	sugar binding site [chemical binding]; other site
699034009684	divalent metal binding site [ion binding]; other site
699034009685	tetramer (dimer of dimers) interface [polypeptide binding]; other site
699034009686	dimer interface [polypeptide binding]; other site
699034009687	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
699034009688	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
699034009689	active site
699034009690	P-loop; other site
699034009691	phosphorylation site [posttranslational modification]
699034009692	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
699034009693	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
699034009694	DNA-binding site [nucleotide binding]; DNA binding site
699034009695	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
699034009696	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
699034009697	Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins; Region: MATE_like_1; cd13140
699034009698	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
699034009699	metal binding site [ion binding]; metal-binding site
699034009700	active site
699034009701	I-site; other site
699034009702	putative 2-aminoethylphosphonate ABC transporter, permease protein; Region: PhnU2; TIGR03262
699034009703	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034009704	dimer interface [polypeptide binding]; other site
699034009705	conserved gate region; other site
699034009706	putative PBP binding loops; other site
699034009707	ABC-ATPase subunit interface; other site
699034009708	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034009709	dimer interface [polypeptide binding]; other site
699034009710	conserved gate region; other site
699034009711	putative PBP binding loops; other site
699034009712	ABC-ATPase subunit interface; other site
699034009713	putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; Region: PhnT2; TIGR03265
699034009714	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034009715	Walker A/P-loop; other site
699034009716	ATP binding site [chemical binding]; other site
699034009717	Q-loop/lid; other site
699034009718	ABC transporter signature motif; other site
699034009719	Walker B; other site
699034009720	D-loop; other site
699034009721	H-loop/switch region; other site
699034009722	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
699034009723	V-type ATP synthase subunit D; Reviewed; Region: PRK00373
699034009724	V-type ATP synthase subunit B; Provisional; Region: PRK04196
699034009725	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
699034009726	V/A-type ATP synthase (non-catalytic) subunit B. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction. The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_B; cd01135
699034009727	Walker A motif homologous position; other site
699034009728	Walker B motif; other site
699034009729	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
699034009730	V-type ATP synthase subunit A; Provisional; Region: PRK04192
699034009731	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
699034009732	V/A-type ATP synthase catalytic subunit A. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction.  The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_A; cd01134
699034009733	Walker A motif/ATP binding site; other site
699034009734	Walker B motif; other site
699034009735	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
699034009736	V-type ATP synthase subunit F; Provisional; Region: PRK01395
699034009737	V-type ATP synthase subunit C; Provisional; Region: PRK01198
699034009738	Archaeal/vacuolar-type H+-ATPase subunit C [Energy production and conversion]; Region: NtpC; COG1527
699034009739	Archaeal/vacuolar-type H+-ATPase subunit E [Energy production and conversion]; Region: NtpE; COG1390
699034009740	V-type ATP synthase subunit K; Validated; Region: PRK06558
699034009741	ATP synthase subunit C; Region: ATP-synt_C; pfam00137
699034009742	ATP synthase subunit C; Region: ATP-synt_C; pfam00137
699034009743	V-type ATP synthase subunit I; Validated; Region: PRK05771
699034009744	Nitrogen fixation protein of unknown function; Region: Nif11; cl06756
699034009745	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
699034009746	Putative peptidoglycan binding domain; Region: PG_binding_4; pfam12229
699034009747	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
699034009748	B3/4 domain; Region: B3_4; cl19243
699034009749	Cache domain; Region: Cache_1; pfam02743
699034009750	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
699034009751	metal binding site [ion binding]; metal-binding site
699034009752	active site
699034009753	I-site; other site
699034009754	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
699034009755	bifunctional acetaldehyde-CoA/alcohol dehydrogenase; Provisional; Region: PRK13805
699034009756	Coenzyme A acylating aldehyde dehydrogenase (ACDH), ALDH family 20-like; Region: ALDH_F20_ACDH; cd07122
699034009757	putative catalytic cysteine [active]
699034009758	C-terminal alcohol dehydrogenase domain of the acetaldehyde dehydrogenase-alcohol dehydrogenase bifunctional two-domain protein (AAD); Region: AAD_C; cd08178
699034009759	putative active site [active]
699034009760	metal binding site [ion binding]; metal-binding site
699034009761	dipicolinate synthase subunit B; Reviewed; Region: spoVFB; PRK08305
699034009762	dipicolinate synthase subunit A; Reviewed; Region: PRK08306
699034009763	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
699034009764	NAD(P) binding pocket [chemical binding]; other site
699034009765	acyl-CoA synthetase; Validated; Region: PRK07638
699034009766	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
699034009767	AMP binding site [chemical binding]; other site
699034009768	active site
699034009769	acyl-activating enzyme (AAE) consensus motif; other site
699034009770	CoA binding site [chemical binding]; other site
699034009771	Thiolase are ubiquitous enzymes that catalyze the reversible thiolytic cleavage of 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA, a 2-step reaction involving a covalent intermediate formed with a catalytic cysteine. They are found in prokaryotes and...; Region: thiolase; cd00751
699034009772	acetyl-CoA acetyltransferases; Region: AcCoA-C-Actrans; TIGR01930
699034009773	dimer interface [polypeptide binding]; other site
699034009774	active site
699034009775	BioY family; Region: BioY; pfam02632
699034009776	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
699034009777	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
699034009778	Coenzyme A binding pocket [chemical binding]; other site
699034009779	CRISPR/Cas system-associated protein Cas2; Region: Cas2_I_II_III; cd09725
699034009780	CRISPR/Cas system-associated protein Cas1; Region: Cas1_I-B; cd09722
699034009781	Domain of unknown function DUF83; Region: Cas_Cas4; pfam01930
699034009782	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
699034009783	CRISPR/Cas system-associated protein Cas3; Region: Cas3_I; cd09639
699034009784	CRISPR-associated helicase Cas3; Region: cas3_core; TIGR01587
699034009785	CRISPR/Cas system-associated RAMP superfamily protein Cas5; Region: Cas5_I-B; cd09658
699034009786	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I-C; cd09687
699034009787	CRISPR/Cas system-associated protein Cas8a1; Region: Cas8a1_I-A; cl18979
699034009788	CRISPR/Cas system-associated RAMP superfamily protein Cas6; Region: Cas6-I-III; cd09652
699034009789	WYL domain; Region: WYL; pfam13280
699034009790	FtsX-like permease family; Region: FtsX; pfam02687
699034009791	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
699034009792	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
699034009793	Walker A/P-loop; other site
699034009794	ATP binding site [chemical binding]; other site
699034009795	Q-loop/lid; other site
699034009796	ABC transporter signature motif; other site
699034009797	Walker B; other site
699034009798	D-loop; other site
699034009799	H-loop/switch region; other site
699034009800	undecaprenyl pyrophosphate phosphatase; Reviewed; Region: PRK00281
699034009801	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034009802	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034009803	dimer interface [polypeptide binding]; other site
699034009804	phosphorylation site [posttranslational modification]
699034009805	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034009806	ATP binding site [chemical binding]; other site
699034009807	Mg2+ binding site [ion binding]; other site
699034009808	G-X-G motif; other site
699034009809	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034009810	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034009811	active site
699034009812	phosphorylation site [posttranslational modification]
699034009813	intermolecular recognition site; other site
699034009814	dimerization interface [polypeptide binding]; other site
699034009815	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034009816	DNA binding site [nucleotide binding]
699034009817	ABC transporter, substrate-binding protein, aliphatic sulfonates family; Region: SsuA_fam; TIGR01728
699034009818	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
699034009819	substrate binding pocket [chemical binding]; other site
699034009820	membrane-bound complex binding site; other site
699034009821	hinge residues; other site
699034009822	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
699034009823	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034009824	Walker A/P-loop; other site
699034009825	ATP binding site [chemical binding]; other site
699034009826	Q-loop/lid; other site
699034009827	ABC transporter signature motif; other site
699034009828	Walker B; other site
699034009829	D-loop; other site
699034009830	H-loop/switch region; other site
699034009831	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
699034009832	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034009833	dimer interface [polypeptide binding]; other site
699034009834	conserved gate region; other site
699034009835	putative PBP binding loops; other site
699034009836	ABC-ATPase subunit interface; other site
699034009837	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
699034009838	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
699034009839	dimer interface [polypeptide binding]; other site
699034009840	putative radical transfer pathway; other site
699034009841	diiron center [ion binding]; other site
699034009842	tyrosyl radical; other site
699034009843	ribonucleotide-diphosphate reductase subunit alpha; Validated; Region: PRK07632
699034009844	Ribonucleotide reductase N-terminal; Region: RNR_N; pfam08343
699034009845	Class I ribonucleotide reductase; Region: RNR_I; cd01679
699034009846	active site
699034009847	dimer interface [polypeptide binding]; other site
699034009848	catalytic residues [active]
699034009849	effector binding site; other site
699034009850	R2 peptide binding site; other site
699034009851	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
699034009852	Pentapeptide repeats (9 copies); Region: Pentapeptide_4; pfam13599
699034009853	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
699034009854	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
699034009855	ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism]; Region: FepC; COG1120
699034009856	ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; Region: ABC_Iron-Siderophores_B12_Hemin; cd03214
699034009857	Walker A/P-loop; other site
699034009858	ATP binding site [chemical binding]; other site
699034009859	Q-loop/lid; other site
699034009860	ABC transporter signature motif; other site
699034009861	Walker B; other site
699034009862	D-loop; other site
699034009863	H-loop/switch region; other site
699034009864	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cl00462
699034009865	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
699034009866	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
699034009867	Probable transposase; Region: OrfB_IS605; pfam01385
699034009868	transposase, IS605 OrfB family, central region; Region: tspaseT_teng_C; TIGR01766
699034009869	Transposase IS200 like; Region: Y1_Tnp; cl00848
699034009870	iron-hydroxamate transporter permease subunit; Provisional; Region: PRK10577
699034009871	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
699034009872	ABC-ATPase subunit  interface; other site
699034009873	dimer interface [polypeptide binding]; other site
699034009874	putative PBP binding regions; other site
699034009875	ABC-type Fe3+-hydroxamate transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: FepB; COG0614
699034009876	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
699034009877	intersubunit interface [polypeptide binding]; other site
699034009878	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
699034009879	inhibitor site; inhibition site
699034009880	active site
699034009881	dimer interface [polypeptide binding]; other site
699034009882	catalytic residue [active]
699034009883	2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism]; Region: MhpD; COG0179
699034009884	Fumarylacetoacetate (FAA) hydrolase family; Region: FAA_hydrolase; pfam01557
699034009885	D-galactarate dehydratase / Altronate hydrolase, C terminus; Region: GD_AH_C; pfam04295
699034009886	Domains similar to fish antifreeze type III protein; Region: SAF_AH_GD; cd11613
699034009887	2-keto-3-deoxygluconate permease; Provisional; Region: PRK05274
699034009888	Transcriptional regulator [Transcription]; Region: IclR; COG1414
699034009889	IclR helix-turn-helix domain; Region: HTH_IclR; cl17605
699034009890	Bacterial transcriptional regulator; Region: IclR; pfam01614
699034009891	Lactadehyde:propanediol oxidoreductase (LPO) catalyzes the interconversion between L-lactaldehyde and L-1,2-propanediol in Escherichia coli and other enterobacteria; Region: LPO; cd08176
699034009892	dimer interface [polypeptide binding]; other site
699034009893	active site
699034009894	metal binding site [ion binding]; metal-binding site
699034009895	Bacterial SH3 domain; Region: SH3_3; pfam08239
699034009896	Bacterial SH3 domain; Region: SH3_3; pfam08239
699034009897	L,D-transpeptidase catalytic domain; Region: YkuD; pfam03734
699034009898	Uncharacterized protein conserved in bacteria [Function unknown]; Region: ErfK; COG1376
699034009899	Uncharacterized conserved protein [Function unknown]; Region: COG2454
699034009900	Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes [Energy production and conversion]; Region: Lpd; COG1249
699034009901	Squalene epoxidase; Region: SE; cl17314
699034009902	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
699034009903	Pyridine nucleotide-disulphide oxidoreductase, dimerization domain; Region: Pyr_redox_dim; pfam02852
699034009904	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
699034009905	TlpA-like family; composed of  TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a...; Region: TlpA_like_family; cd02966
699034009906	catalytic residues [active]
699034009907	Predicted transcriptional regulators [Transcription]; Region: COG1733
699034009908	alpha-mannosidase; Provisional; Region: PRK09819
699034009909	N-terminal catalytic domain of Escherichia coli alpha-mannosidase MngB and its bacterial homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_EcMngB_like; cd10815
699034009910	active site
699034009911	metal binding site [ion binding]; metal-binding site
699034009912	catalytic site [active]
699034009913	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; cl08536
699034009914	Glycosyl hydrolases family 38 C-terminal domain; Region: Glyco_hydro_38C; pfam07748
699034009915	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
699034009916	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
699034009917	active site
699034009918	P-loop; other site
699034009919	phosphorylation site [posttranslational modification]
699034009920	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
699034009921	active site
699034009922	phosphorylation site [posttranslational modification]
699034009923	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
699034009924	Mga helix-turn-helix domain; Region: Mga; pfam05043
699034009925	HTH domain; Region: HTH_11; pfam08279
699034009926	PRD domain; Region: PRD; pfam00874
699034009927	PRD domain; Region: PRD; pfam00874
699034009928	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
699034009929	active site
699034009930	P-loop; other site
699034009931	phosphorylation site [posttranslational modification]
699034009932	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
699034009933	active site
699034009934	phosphorylation site [posttranslational modification]
699034009935	Putative glucose uptake permease [Carbohydrate transport and metabolism]; Region: GlcU; COG4975
699034009936	Putative redox-active protein (C_GCAxxG_C_C); Region: C_GCAxxG_C_C; pfam09719
699034009937	C4-dicarboxylate transporters of the Tellurite-resistance/Dicarboxylate Transporter (TDT) family; Region: TDT_C4-dicarb_trans; cd09325
699034009938	gating phenylalanine in ion channel; other site
699034009939	Domain of unknown function (DUF1848); Region: DUF1848; pfam08902
699034009940	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
699034009941	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
699034009942	Right handed beta helix region; Region: Beta_helix; pfam13229
699034009943	Pectate lyase superfamily protein; Region: Pectate_lyase_3; pfam12708
699034009944	4Fe-4S double cluster binding domain; Region: Fer4_16; pfam13484
699034009945	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
699034009946	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
699034009947	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257
699034009948	Uncharacterized protein conserved in bacteria (DUF2087); Region: DUF2087; pfam09860
699034009949	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
699034009950	HPr interaction site; other site
699034009951	glycerol kinase (GK) interaction site [polypeptide binding]; other site
699034009952	active site
699034009953	phosphorylation site [posttranslational modification]
699034009954	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
699034009955	putative active site [active]
699034009956	putative C-S lyase; Region: C_S_lyase_PatB; TIGR04350
699034009957	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
699034009958	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034009959	homodimer interface [polypeptide binding]; other site
699034009960	catalytic residue [active]
699034009961	bifunctional PTS system maltose and glucose-specific transporter subunits IICB; Provisional; Region: PRK10110
699034009962	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
699034009963	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
699034009964	active site turn [active]
699034009965	phosphorylation site [posttranslational modification]
699034009966	transcriptional antiterminator BglG; Provisional; Region: PRK09772
699034009967	CAT RNA binding domain; Region: CAT_RBD; smart01061
699034009968	PRD domain; Region: PRD; pfam00874
699034009969	PRD domain; Region: PRD; pfam00874
699034009970	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
699034009971	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
699034009972	catalytic residue [active]
699034009973	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
699034009974	catalytic residues [active]
699034009975	Predicted transcriptional regulators [Transcription]; Region: COG1378
699034009976	Sugar-specific transcriptional regulator TrmB; Region: TrmB; pfam01978
699034009977	Middle phospholipase D-like domain of the transcriptional regulator TrmB and similar proteins; Region: PLDc_like_TrmB_middle; cd09124
699034009978	C-terminal domain interface [polypeptide binding]; other site
699034009979	sugar binding site [chemical binding]; other site
699034009980	Predicted epimerase, PhzC/PhzF homolog [General function prediction only]; Region: COG0384
699034009981	Diaminopimelate epimerase; Region: DAP_epimerase; cl19724
699034009982	Dipeptide/tripeptide permease [Amino acid transport and metabolism]; Region: PTR2; COG3104
699034009983	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
699034009984	putative substrate translocation pore; other site
699034009985	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
699034009986	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3864
699034009987	Putative metallopeptidase domain; Region: DUF2201_N; pfam13203
699034009988	Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of...; Region: vWFA; cd00198
699034009989	metal ion-dependent adhesion site (MIDAS); other site
699034009990	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
699034009991	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034009992	Walker A motif; other site
699034009993	ATP binding site [chemical binding]; other site
699034009994	Walker B motif; other site
699034009995	PrkA serine protein kinase C-terminal domain; Region: PrkA; pfam06798
699034009996	proline-specific peptidase, Bacillus coagulans-type subfamily; Region: pro_imino_pep_2; TIGR01250
699034009997	Putative lysophospholipase; Region: Hydrolase_4; cl19140
699034009998	Predicted membrane protein [Function unknown]; Region: COG4129
699034009999	Bacterial protein of unknown function (DUF939); Region: DUF939; pfam06081
699034010000	DUF939 C-terminal domain; Region: DUF939_C; pfam11728
699034010001	Transglutaminase-like superfamily; Region: Transglut_core; pfam01841
699034010002	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
699034010003	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
699034010004	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
699034010005	putative active site [active]
699034010006	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
699034010007	BadF/BadG/BcrA/BcrD ATPase family; Region: BcrAD_BadFG; cl17271
699034010008	N-acetylmuramic acid 6-phosphate etherase; Region: TIGR00274
699034010009	N-acetylmuramic acid 6-phosphate etherase. Members of this family contain the SIS (Sugar ISomerase) domain. The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. The bacterial cell wall sugar N-acetylmuramic acid...; Region: SIS_Etherase; cd05007
699034010010	putative active site [active]
699034010011	Bacterial protein of unknown function (DUF871); Region: DUF871; pfam05913
699034010012	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
699034010013	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
699034010014	active site
699034010015	P-loop; other site
699034010016	phosphorylation site [posttranslational modification]
699034010017	anhydro-N-acetylmuramic acid kinase; Reviewed; Region: anmK; PRK09585
699034010018	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034010019	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034010020	ATP binding site [chemical binding]; other site
699034010021	Mg2+ binding site [ion binding]; other site
699034010022	G-X-G motif; other site
699034010023	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034010024	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034010025	active site
699034010026	phosphorylation site [posttranslational modification]
699034010027	intermolecular recognition site; other site
699034010028	dimerization interface [polypeptide binding]; other site
699034010029	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034010030	DNA binding site [nucleotide binding]
699034010031	FtsX-like permease family; Region: FtsX; pfam02687
699034010032	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
699034010033	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
699034010034	Walker A/P-loop; other site
699034010035	ATP binding site [chemical binding]; other site
699034010036	Q-loop/lid; other site
699034010037	ABC transporter signature motif; other site
699034010038	Walker B; other site
699034010039	D-loop; other site
699034010040	H-loop/switch region; other site
699034010041	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
699034010042	Major Facilitator Superfamily; Region: MFS_1; pfam07690
699034010043	putative substrate translocation pore; other site
699034010044	PTS_IIA, PTS system, glucose/sucrose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_glc; cl00162
699034010045	HPr interaction site; other site
699034010046	glycerol kinase (GK) interaction site [polypeptide binding]; other site
699034010047	active site
699034010048	phosphorylation site [posttranslational modification]
699034010049	Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases [Carbohydrate transport and metabolism]; Region: CelF; COG1486
699034010050	Glycoside Hydrolases Family 4; GlvA- and pagL-like glycosidases; Region: GH4_GlvA_pagL_like; cd05298
699034010051	NAD binding site [chemical binding]; other site
699034010052	sugar binding site [chemical binding]; other site
699034010053	divalent metal binding site [ion binding]; other site
699034010054	putative tetramer (dimer of dimers) interface [polypeptide binding]; other site
699034010055	dimer interface [polypeptide binding]; other site
699034010056	PTS system, alpha-glucoside-specific IIBC component; Region: PTS-IIBC-alpha; TIGR02005
699034010057	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
699034010058	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
699034010059	active site turn [active]
699034010060	phosphorylation site [posttranslational modification]
699034010061	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
699034010062	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
699034010063	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
699034010064	putative active site [active]
699034010065	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
699034010066	Active site serine [active]
699034010067	xylose isomerase; Provisional; Region: PRK05474
699034010068	Escherichia coli xylulokinase-like D-xylulose kinases; a subgroup of the FGGY family of carbohydrate kinases; Region: FGGY_D-XK_EcXK-like; cd07808
699034010069	N- and C-terminal domain interface [polypeptide binding]; other site
699034010070	D-xylulose kinase; Region: XylB; TIGR01312
699034010071	active site
699034010072	MgATP binding site [chemical binding]; other site
699034010073	catalytic site [active]
699034010074	metal binding site [ion binding]; metal-binding site
699034010075	xylulose binding site [chemical binding]; other site
699034010076	homodimer interface [polypeptide binding]; other site
699034010077	Transcriptional regulators [Transcription]; Region: MarR; COG1846
699034010078	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
699034010079	Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism]; Region: NagC; COG1940
699034010080	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cd00012
699034010081	nucleotide binding site [chemical binding]; other site
699034010082	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
699034010083	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cd00006
699034010084	active pocket/dimerization site; other site
699034010085	active site
699034010086	phosphorylation site [posttranslational modification]
699034010087	PTS system sorbose subfamily IIB component; Region: PTSIIB_sorb; pfam03830
699034010088	active site
699034010089	phosphorylation site [posttranslational modification]
699034010090	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
699034010091	PTS system sorbose-specific iic component; Region: EII-Sor; pfam03609
699034010092	Galactose mutarotase-like; Region: Gal_mutarotas_2; pfam13802
699034010093	Glycosyl hydrolases family 31; Region: Glyco_hydro_31; pfam01055
699034010094	XylS is a glycosyl hydrolase family 31 (GH31) alpha-xylosidase found in prokaryotes, eukaryotes, and archaea, that catalyzes the release of alpha-xylose from the non-reducing terminal side of the alpha-xyloside substrate. XylS has been characterized in...; Region: GH31_xylosidase_XylS; cd06591
699034010095	putative active site [active]
699034010096	putative catalytic site [active]
699034010097	Protein of unknown function (DUF523); Region: DUF523; cl00733
699034010098	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
699034010099	Protein of unknown function DUF262; Region: DUF262; pfam03235
699034010100	Protein of unknown function (DUF1524); Region: DUF1524; pfam07510
699034010101	Domain of unknown function (DUF4145); Region: DUF4145; pfam13643
699034010102	Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms]; Region: HsdR; COG4096
699034010103	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N; pfam04313
699034010104	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
699034010105	ATP binding site [chemical binding]; other site
699034010106	putative Mg++ binding site [ion binding]; other site
699034010107	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
699034010108	nucleotide binding region [chemical binding]; other site
699034010109	ATP-binding site [chemical binding]; other site
699034010110	EcoEI R protein C-terminal; Region: EcoEI_R_C; pfam08463
699034010111	Nucleotidyltransferase (NT) domain of Staphylococcus aureus kanamycin nucleotidyltransferase, and similar proteins; Region: NT_KNTase_like; cd05403
699034010112	active site
699034010113	NTP binding site [chemical binding]; other site
699034010114	metal binding triad [ion binding]; metal-binding site
699034010115	antibiotic binding site [chemical binding]; other site
699034010116	Restriction endonuclease S subunits [Defense mechanisms]; Region: HsdS; COG0732
699034010117	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
699034010118	Type I restriction modification DNA specificity domain; Region: Methylase_S; pfam01420
699034010119	Type I restriction-modification system methyltransferase subunit [Defense mechanisms]; Region: HsdM; COG0286
699034010120	HsdM N-terminal domain; Region: HsdM_N; pfam12161
699034010121	Methyltransferase domain; Region: Methyltransf_26; pfam13659
699034010122	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
699034010123	intersubunit interface [polypeptide binding]; other site
699034010124	active site
699034010125	zinc binding site [ion binding]; other site
699034010126	Na+ binding site [ion binding]; other site
699034010127	putative PTS system  transporter subunits IIBC; Provisional; Region: PRK11404
699034010128	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
699034010129	active site
699034010130	P-loop; other site
699034010131	phosphorylation site [posttranslational modification]
699034010132	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
699034010133	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
699034010134	active site
699034010135	phosphorylation site [posttranslational modification]
699034010136	Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) [Carbohydrate transport and metabolism]; Region: FruK; COG1105
699034010137	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
699034010138	putative substrate binding site [chemical binding]; other site
699034010139	putative ATP binding site [chemical binding]; other site
699034010140	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
699034010141	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
699034010142	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
699034010143	putative active site [active]
699034010144	Predicted membrane protein [Function unknown]; Region: COG2364
699034010145	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
699034010146	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; pfam00232
699034010147	PTS system, Lactose/Cellobiose specific IIA subunit; Region: PTS_IIA; pfam02255
699034010148	active site
699034010149	methionine cluster; other site
699034010150	phosphorylation site [posttranslational modification]
699034010151	metal binding site [ion binding]; metal-binding site
699034010152	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
699034010153	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
699034010154	active site
699034010155	P-loop; other site
699034010156	phosphorylation site [posttranslational modification]
699034010157	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
699034010158	HTH domain; Region: HTH_11; pfam08279
699034010159	Mga helix-turn-helix domain; Region: Mga; pfam05043
699034010160	PRD domain; Region: PRD; pfam00874
699034010161	PRD domain; Region: PRD; pfam00874
699034010162	PTS_IIB: subunit IIB of enzyme II (EII) is the central energy-coupling domain of the phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In the multienzyme PTS complex, EII is a carbohydrate-specific permease consisting of two cytoplasmic...; Region: PTS_IIB; cl10014
699034010163	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; Region: PTS_EIIA_2; pfam00359
699034010164	active site
699034010165	phosphorylation site [posttranslational modification]
699034010166	Glycerate kinase [Carbohydrate transport and metabolism]; Region: COG1929
699034010167	alpha-mannosidase; Provisional; Region: PRK09819
699034010168	N-terminal catalytic domain of Escherichia coli alpha-mannosidase MngB and its bacterial homologs; glycoside hydrolase family 38 (GH38); Region: GH38N_AMII_EcMngB_like; cd10815
699034010169	active site
699034010170	metal binding site [ion binding]; metal-binding site
699034010171	catalytic site [active]
699034010172	Alpha mannosidase, middle domain; Region: Alpha-mann_mid; smart00872
699034010173	Glycosyl hydrolases family 38 C-terminal domain; Region: Glyco_hydro_38C; pfam07748
699034010174	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
699034010175	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
699034010176	active site
699034010177	phosphorylation site [posttranslational modification]
699034010178	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
699034010179	active site
699034010180	P-loop; other site
699034010181	phosphorylation site [posttranslational modification]
699034010182	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
699034010183	Transcriptional regulators [Transcription]; Region: RpiR; COG1737
699034010184	Helix-turn-helix domain, rpiR family; Region: HTH_6; pfam01418
699034010185	RpiR-like protein. RpiR contains a SIS (Sugar ISomerase) domain, which is found in many phosphosugar isomerases and phosphosugar binding proteins. In E. coli, rpiR negatively regulates the expression of rpiB gene. Both rpiB and rpiA are ribose phosphate...; Region: SIS_RpiR; cd05013
699034010186	putative active site [active]
699034010187	uncharacterized YdjC-like family proteins from bacteria; Region: YdjC_like_1; cd10805
699034010188	putative active site [active]
699034010189	YdjC motif; other site
699034010190	Mg binding site [ion binding]; other site
699034010191	putative homodimer interface [polypeptide binding]; other site
699034010192	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
699034010193	PTS system, N-acetylglucosamine-specific IIBC component; Region: PTS-II-BC-nag; TIGR01998
699034010194	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
699034010195	active site turn [active]
699034010196	phosphorylation site [posttranslational modification]
699034010197	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
699034010198	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
699034010199	DNA-binding site [nucleotide binding]; DNA binding site
699034010200	The UbiC transcription regulator-associated (UTRA) domain is a conserved ligand-binding domain; Region: UTRA; smart00866
699034010201	alpha,alpha-phosphotrehalase; Region: trehalose_treC; TIGR02403
699034010202	Alpha amylase catalytic domain found in Sucrose isomerases, oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), dextran glucosidase (also called glucan 1,6-alpha-glucosidase), and related proteins; Region: AmyAc_SI_OligoGlu_DGase; cd11333
699034010203	Ca binding site [ion binding]; other site
699034010204	active site
699034010205	catalytic site [active]
699034010206	amino acid transporter; Region: 2A0306; TIGR00909
699034010207	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; cl17316
699034010208	Transmembrane amino acid transporter protein; Region: Aa_trans; cl17468
699034010209	Predicted glutamine amidotransferases [General function prediction only]; Region: COG2071
699034010210	Subgroup of proteins having the Type 1 glutamine amidotransferase (GATase1) domain; Region: GATase1_2; cd01745
699034010211	catalytic triad [active]
699034010212	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
699034010213	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034010214	Walker A motif; other site
699034010215	ATP binding site [chemical binding]; other site
699034010216	Walker B motif; other site
699034010217	arginine finger; other site
699034010218	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; pfam00232
699034010219	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; COG2723
699034010220	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
699034010221	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
699034010222	active site turn [active]
699034010223	phosphorylation site [posttranslational modification]
699034010224	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
699034010225	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
699034010226	HPr interaction site; other site
699034010227	glycerol kinase (GK) interaction site [polypeptide binding]; other site
699034010228	active site
699034010229	phosphorylation site [posttranslational modification]
699034010230	transcriptional antiterminator BglG; Provisional; Region: PRK09772
699034010231	CAT RNA binding domain; Region: CAT_RBD; smart01061
699034010232	PRD domain; Region: PRD; pfam00874
699034010233	PRD domain; Region: PRD; pfam00874
699034010234	M20 Peptidase Aminoacylase 1-like protein 2-like, amidohydrolase subfamily; Region: M20_ACY1L2_like; cd05672
699034010235	Peptidase family M20/M25/M40; Region: Peptidase_M20; pfam01546
699034010236	metal binding site [ion binding]; metal-binding site
699034010237	Predicted membrane protein [Function unknown]; Region: COG1288
699034010238	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
699034010239	PTS system, glucose-specific IIBC component; Region: PTS-II-BC-glcB; TIGR02002
699034010240	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
699034010241	active site turn [active]
699034010242	phosphorylation site [posttranslational modification]
699034010243	dipeptidase PepV; Reviewed; Region: PRK07318
699034010244	M20 Peptidase Xaa-His dipeptidase (PepV) degrades hydrophobic dipeptides; Region: M20_PepV; cd03888
699034010245	active site
699034010246	metal binding site [ion binding]; metal-binding site
699034010247	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
699034010248	HPr interaction site; other site
699034010249	glycerol kinase (GK) interaction site [polypeptide binding]; other site
699034010250	active site
699034010251	phosphorylation site [posttranslational modification]
699034010252	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
699034010253	haloacid dehalogenase-like hydrolase; Region: Hydrolase_3; pfam08282
699034010254	active site
699034010255	motif I; other site
699034010256	motif II; other site
699034010257	haloacid dehalogenase-like hydrolase; Region: HAD; cl19137
699034010258	Iron-containing alcohol dehydrogenases-like; Region: Fe-ADH1; cd08185
699034010259	putative active site [active]
699034010260	metal binding site [ion binding]; metal-binding site
699034010261	Class I aldolases; Region: Aldolase_Class_I; cl17187
699034010262	catalytic residue [active]
699034010263	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
699034010264	HTH domain; Region: HTH_11; pfam08279
699034010265	Mga helix-turn-helix domain; Region: Mga; pfam05043
699034010266	PRD domain; Region: PRD; pfam00874
699034010267	PRD domain; Region: PRD; pfam00874
699034010268	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
699034010269	active site
699034010270	P-loop; other site
699034010271	phosphorylation site [posttranslational modification]
699034010272	Uncharacterized conserved protein [Function unknown]; Region: COG1284
699034010273	Domain of unknown function (DUF373); Region: DUF373; cl12079
699034010274	TIM barrel proteins share a structurally conserved phosphate binding motif and in general share an eight beta/alpha closed barrel structure. Specific for this family is the conserved phosphate binding site at the edges of strands 7 and 8. The phosphate...; Region: TIM_phosphate_binding; cl17186
699034010275	phosphate binding site [ion binding]; other site
699034010276	6-phosphofructokinase; Provisional; Region: PRK14072
699034010277	active site
699034010278	ADP/pyrophosphate binding site [chemical binding]; other site
699034010279	dimerization interface [polypeptide binding]; other site
699034010280	allosteric effector site; other site
699034010281	fructose-1,6-bisphosphate binding site; other site
699034010282	Transposase IS200 like; Region: Y1_Tnp; cl00848
699034010283	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
699034010284	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
699034010285	Probable transposase; Region: OrfB_IS605; pfam01385
699034010286	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
699034010287	Predicted transcriptional regulator [Transcription]; Region: COG3355
699034010288	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
699034010289	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
699034010290	metal binding site [ion binding]; metal-binding site
699034010291	dimer interface [polypeptide binding]; other site
699034010292	M20 Peptidase Aminoacylase 1-like protein 2 aminobenzoyl-glutamate utilization protein B subfamily; Region: M20_Acy1L2_AbgB; cd05673
699034010293	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
699034010294	putative metal binding site [ion binding]; other site
699034010295	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; cl01046
699034010296	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; pfam00232
699034010297	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
699034010298	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
699034010299	active site turn [active]
699034010300	phosphorylation site [posttranslational modification]
699034010301	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
699034010302	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
699034010303	HPr interaction site; other site
699034010304	glycerol kinase (GK) interaction site [polypeptide binding]; other site
699034010305	active site
699034010306	phosphorylation site [posttranslational modification]
699034010307	transcriptional antiterminator BglG; Provisional; Region: PRK09772
699034010308	CAT RNA binding domain; Region: CAT_RBD; smart01061
699034010309	PRD domain; Region: PRD; pfam00874
699034010310	PRD domain; Region: PRD; pfam00874
699034010311	Protein of unknown function (DUF3139); Region: DUF3139; pfam11337
699034010312	This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the...; Region: GT1_Gtf_like; cd03784
699034010313	glycosyltransferase, MGT family; Region: MGT; TIGR01426
699034010314	active site
699034010315	TDP-binding site; other site
699034010316	acceptor substrate-binding pocket; other site
699034010317	homodimer interface [polypeptide binding]; other site
699034010318	Regulators of stationary/sporulation gene expression [Transcription]; Region: AbrB; COG2002
699034010319	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
699034010320	Serine Recombinase (SR) family, TndX-like transposase subfamily, catalytic domain; composed of large serine recombinases similar to Clostridium TndX and TnpX transposases. Serine recombinases catalyze site-specific recombination of DNA molecules by a...; Region: SR_TndX_transposase; cd03770
699034010321	putative catalytic residues [active]
699034010322	catalytic nucleophile [active]
699034010323	Recombinase; Region: Recombinase; pfam07508
699034010324	Recombinase zinc beta ribbon domain; Region: Zn_ribbon_recom; pfam13408
699034010325	Domain of unknown function (DUF4368); Region: DUF4368; pfam14287
699034010326	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034010327	non-specific DNA binding site [nucleotide binding]; other site
699034010328	salt bridge; other site
699034010329	sequence-specific DNA binding site [nucleotide binding]; other site
699034010330	Replication initiation factor; Region: Rep_trans; pfam02486
699034010331	Protein of unknown function (DUF2500); Region: DUF2500; pfam10694
699034010332	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
699034010333	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034010334	non-specific DNA binding site [nucleotide binding]; other site
699034010335	salt bridge; other site
699034010336	sequence-specific DNA binding site [nucleotide binding]; other site
699034010337	mycofactocin system FadH/OYE family oxidoreductase 2; Region: mycofact_OYE_2; TIGR03997
699034010338	Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day.  Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a...; Region: OYE_like_FMN_family; cd02803
699034010339	active site
699034010340	FMN binding site [chemical binding]; other site
699034010341	substrate binding site [chemical binding]; other site
699034010342	putative catalytic residue [active]
699034010343	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
699034010344	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
699034010345	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
699034010346	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
699034010347	putative substrate translocation pore; other site
699034010348	Predicted transcriptional regulators [Transcription]; Region: COG1695
699034010349	Virulence activator alpha C-term; Region: Vir_act_alpha_C; pfam10400
699034010350	Flavodoxin domain; Region: Flavodoxin_5; cl17428
699034010351	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
699034010352	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
699034010353	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
699034010354	dimerization interface [polypeptide binding]; other site
699034010355	putative DNA binding site [nucleotide binding]; other site
699034010356	putative Zn2+ binding site [ion binding]; other site
699034010357	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
699034010358	4Fe-4S dicluster domain; Region: Fer4_10; pfam13237
699034010359	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514
699034010360	FMN binding site [chemical binding]; other site
699034010361	dimer interface [polypeptide binding]; other site
699034010362	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; cl01046
699034010363	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; pfam00232
699034010364	PTS system, beta-glucoside-specific IIABC component; Region: PTS-II-ABC-beta; TIGR01995
699034010365	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
699034010366	active site turn [active]
699034010367	phosphorylation site [posttranslational modification]
699034010368	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
699034010369	Phosphotransferase system IIA components [Carbohydrate transport and metabolism]; Region: NagE; COG2190
699034010370	HPr interaction site; other site
699034010371	glycerol kinase (GK) interaction site [polypeptide binding]; other site
699034010372	active site
699034010373	phosphorylation site [posttranslational modification]
699034010374	transcriptional antiterminator BglG; Provisional; Region: PRK09772
699034010375	CAT RNA binding domain; Region: CAT_RBD; smart01061
699034010376	PRD domain; Region: PRD; pfam00874
699034010377	PRD domain; Region: PRD; pfam00874
699034010378	PTS system cellobiose/arbutin/salicin-specific transporter subunits IIBC; Provisional; Region: PRK09796
699034010379	PTS_IIB, PTS system, glucose/sucrose specific IIB subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIB_glc; cd00212
699034010380	active site turn [active]
699034010381	phosphorylation site [posttranslational modification]
699034010382	Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific [Carbohydrate transport and metabolism]; Region: PtsG; COG1263
699034010383	beta-phosphoglucomutase; Region: bPGM; TIGR01990
699034010384	haloacid dehalogenase-like hydrolase; Region: HAD; pfam12710
699034010385	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
699034010386	motif II; other site
699034010387	Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism]; Region: ATH1; COG1554
699034010388	Glycosyl hydrolase family 65, N-terminal domain; Region: Glyco_hydro_65N; pfam03636
699034010389	Glycosyl hydrolase family 65 central catalytic domain; Region: Glyco_hydro_65m; pfam03632
699034010390	Glycosyl hydrolase family 65, C-terminal domain; Region: Glyco_hydro_65C; pfam03633
699034010391	Glycosyl hydrolase family 1; Region: Glyco_hydro_1; pfam00232
699034010392	Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase [Carbohydrate transport and metabolism]; Region: BglB; cl01046
699034010393	AraC-like ligand binding domain; Region: AraC_binding; pfam02311
699034010394	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
699034010395	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
699034010396	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
699034010397	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
699034010398	active site
699034010399	phosphorylation site [posttranslational modification]
699034010400	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
699034010401	HTH domain; Region: HTH_11; pfam08279
699034010402	Mga helix-turn-helix domain; Region: Mga; pfam05043
699034010403	PRD domain; Region: PRD; pfam00874
699034010404	PRD domain; Region: PRD; pfam00874
699034010405	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
699034010406	active site
699034010407	P-loop; other site
699034010408	phosphorylation site [posttranslational modification]
699034010409	PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional; Region: PRK09765
699034010410	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
699034010411	active site
699034010412	phosphorylation site [posttranslational modification]
699034010413	PTS_IIB_fructose: subunit IIB of enzyme II (EII) of the fructose-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII (also referred to as FruAB) is a fructose-specific permease made up of two proteins (FruA and...; Region: PTS_IIB_fructose; cd05569
699034010414	active site
699034010415	P-loop; other site
699034010416	phosphorylation site [posttranslational modification]
699034010417	Phosphotransferase system, fructose-specific IIC component [Carbohydrate transport and metabolism]; Region: FruA; COG1299
699034010418	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
699034010419	intersubunit interface [polypeptide binding]; other site
699034010420	active site
699034010421	zinc binding site [ion binding]; other site
699034010422	Na+ binding site [ion binding]; other site
699034010423	ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism]; Region: ThiP; COG1178
699034010424	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034010425	dimer interface [polypeptide binding]; other site
699034010426	conserved gate region; other site
699034010427	putative PBP binding loops; other site
699034010428	ABC-ATPase subunit interface; other site
699034010429	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034010430	dimer interface [polypeptide binding]; other site
699034010431	conserved gate region; other site
699034010432	putative PBP binding loops; other site
699034010433	ABC-ATPase subunit interface; other site
699034010434	ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism]; Region: PotA; COG3842
699034010435	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034010436	Walker A/P-loop; other site
699034010437	ATP binding site [chemical binding]; other site
699034010438	Q-loop/lid; other site
699034010439	ABC transporter signature motif; other site
699034010440	Walker B; other site
699034010441	D-loop; other site
699034010442	H-loop/switch region; other site
699034010443	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
699034010444	ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism]; Region: AfuA; COG1840
699034010445	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034010446	sequence-specific DNA binding site [nucleotide binding]; other site
699034010447	salt bridge; other site
699034010448	Type 1 glutamine amidotransferase (GATase1)-like domain found in a subgroup of proteins similar to PfpI from Pyrococcus furiosus; Region: GATase1_PfpI_3; cd03140
699034010449	Putative intracellular protease/amidase [General function prediction only]; Region: ThiJ; COG0693
699034010450	conserved cys residue [active]
699034010451	Predicted transcriptional regulator [Transcription]; Region: COG2378
699034010452	HTH domain; Region: HTH_11; pfam08279
699034010453	WYL domain; Region: WYL; pfam13280
699034010454	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034010455	non-specific DNA binding site [nucleotide binding]; other site
699034010456	salt bridge; other site
699034010457	sequence-specific DNA binding site [nucleotide binding]; other site
699034010458	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
699034010459	Uncharacterized protein conserved in bacteria C-term(DUF2220); Region: DUF2220; pfam09983
699034010460	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG2963
699034010461	'potential frameshift: common BLAST hit: gi|260686438|ref|YP_003217571.1| integrase, catalytic region'
699034010462	Protein of unknown function DUF262; Region: DUF262; pfam03235
699034010463	FRG domain; Region: FRG; pfam08867
699034010464	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cl17200
699034010465	Transposase DDE domain; Region: DDE_Tnp_1_6; pfam13751
699034010466	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3666
699034010467	CRISPR/Cas system-associated protein Cas3'' Region: Cas3''_I; cd09641
699034010468	CRISPR/Cas system-associated protein Cas3; Region: Cas3_I; cd09639
699034010469	CRISPR-associated helicase Cas3; Region: cas3_core; TIGR01587
699034010470	CRISPR/Cas system-associated RAMP superfamily protein Cas7; Region: Cas7_I; cl00803
699034010471	CRISPR/Cas system-associated RAMP superfamily protein Cas6; Region: Cas6-I-III; cl11443
699034010472	potential frameshift: common BLAST hit: gi|260688339|ref|YP_003219473.1| CRISPR-associated protein cas5 family
699034010473	Predicted restriction endonuclease [Defense mechanisms]; Region: COG3183
699034010474	HNH nucleases; HNH endonuclease signature which is found in viral, prokaryotic, and eukaryotic proteins. The alignment includes members of the large group of homing endonucleases, yeast intron 1 protein, MutS, as well as bacterial colicins, pyocins, and...; Region: HNHc; cd00085
699034010475	active site
699034010476	phage replicative helicase, DnaB family, HK022 subfamily; Region: phage_DnaB; TIGR03600
699034010477	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
699034010478	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
699034010479	Walker A motif; other site
699034010480	ATP binding site [chemical binding]; other site
699034010481	Walker B motif; other site
699034010482	Putative primosome component and related proteins [DNA replication, recombination, and repair]; Region: DnaD; COG3935
699034010483	Excisionase from transposon Tn916; Region: Tn916-Xis; pfam09035
699034010484	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
699034010485	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034010486	non-specific DNA binding site [nucleotide binding]; other site
699034010487	salt bridge; other site
699034010488	sequence-specific DNA binding site [nucleotide binding]; other site
699034010489	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
699034010490	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034010491	non-specific DNA binding site [nucleotide binding]; other site
699034010492	salt bridge; other site
699034010493	sequence-specific DNA binding site [nucleotide binding]; other site
699034010494	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
699034010495	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034010496	non-specific DNA binding site [nucleotide binding]; other site
699034010497	salt bridge; other site
699034010498	sequence-specific DNA binding site [nucleotide binding]; other site
699034010499	Fic family protein [Function unknown]; Region: COG3177
699034010500	Fic/DOC family; Region: Fic; pfam02661
699034010501	Phage integrase, N-terminal SAM-like domain; Region: Phage_int_SAM_3; pfam14659
699034010502	Integrase [DNA replication, recombination, and repair]; Region: XerC; COG0582
699034010503	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
699034010504	DNA binding site [nucleotide binding]
699034010505	Int/Topo IB signature motif; other site
699034010506	active site
699034010507	Protein of unknown function (DUF3990); Region: DUF3990; pfam13151
699034010508	Protein of unknown function (DUF3791); Region: DUF3791; pfam12668
699034010509	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3677
699034010510	P63C domain; Region: P63C; pfam10546
699034010511	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
699034010512	SmpB-tmRNA interface; other site
699034010513	Mitochondrial biogenesis AIM24; Region: AIM24; pfam01987
699034010514	Acetyltransferase (GNAT) domain; Region: Acetyltransf_3; pfam13302
699034010515	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
699034010516	Coenzyme A binding pocket [chemical binding]; other site
699034010517	Uncharacterized conserved protein [Function unknown]; Region: COG1615; cl09133
699034010518	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
699034010519	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
699034010520	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
699034010521	ABC-type multidrug transport system, ATPase component; Region: ABC_drug_resistance_like; cd03264
699034010522	Walker A/P-loop; other site
699034010523	ATP binding site [chemical binding]; other site
699034010524	Q-loop/lid; other site
699034010525	ABC transporter signature motif; other site
699034010526	Walker B; other site
699034010527	D-loop; other site
699034010528	H-loop/switch region; other site
699034010529	Domain of unknown function (DUF1877); Region: DUF1877; pfam08974
699034010530	ribonuclease R; Region: RNase_R; TIGR02063
699034010531	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
699034010532	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
699034010533	RNB domain; Region: RNB; pfam00773
699034010534	S1_RNase_R: RNase R C-terminal S1 domain. RNase R is a processive 3' to 5' exoribonuclease, which is a homolog of RNase II. RNase R degrades RNA with secondary structure having a 3' overhang of at least 7 nucleotides. RNase R and PNPase...; Region: S1_RNase_R; cd04471
699034010535	RNA binding site [nucleotide binding]; other site
699034010536	A new structural DNA glycosylase; Region: AlkD_like; cl11434
699034010537	HEAT repeats; Region: HEAT_2; pfam13646
699034010538	active site
699034010539	Predicted transcriptional regulators [Transcription]; Region: COG1733
699034010540	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
699034010541	substrate binding site [chemical binding]; other site
699034010542	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_2; cd07253
699034010543	dimer interface [polypeptide binding]; other site
699034010544	metal binding site [ion binding]; metal-binding site
699034010545	Predicted permeases [General function prediction only]; Region: COG0679
699034010546	protein translocase, SecG subunit; Region: secG; TIGR00810
699034010547	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
699034010548	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
699034010549	Coenzyme A binding pocket [chemical binding]; other site
699034010550	Transcriptional regulators [Transcription]; Region: MarR; COG1846
699034010551	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cl17220
699034010552	enolase; Provisional; Region: eno; PRK00077
699034010553	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
699034010554	dimer interface [polypeptide binding]; other site
699034010555	metal binding site [ion binding]; metal-binding site
699034010556	substrate binding pocket [chemical binding]; other site
699034010557	phosphoglyceromutase; Provisional; Region: PRK05434
699034010558	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
699034010559	substrate binding site [chemical binding]; other site
699034010560	dimer interface [polypeptide binding]; other site
699034010561	catalytic triad [active]
699034010562	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
699034010563	substrate binding site [chemical binding]; other site
699034010564	hinge regions; other site
699034010565	ADP binding site [chemical binding]; other site
699034010566	catalytic site [active]
699034010567	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
699034010568	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; smart00846
699034010569	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
699034010570	Transcriptional regulator, contains sigma factor-related N-terminal domain [Transcription]; Region: DeoR; COG2390
699034010571	Predicted transcriptional regulator [Transcription]; Region: COG3388
699034010572	Putative sugar-binding domain; Region: Sugar-bind; pfam04198
699034010573	RNA polymerase factor sigma-54; Reviewed; Region: PRK05932
699034010574	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
699034010575	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
699034010576	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
699034010577	selenium-dependent molybdenum hydroxylase 1; Region: Se_dep_Molyb_1; TIGR03311
699034010578	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
699034010579	catalytic loop [active]
699034010580	iron binding site [ion binding]; other site
699034010581	[2Fe-2S] binding domain; Region: Fer2_2; pfam01799
699034010582	Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain; Region: Ald_Xan_dh_C; smart01008
699034010583	Molybdopterin-binding domain of aldehyde dehydrogenase; Region: Ald_Xan_dh_C2; pfam02738
699034010584	phenylhydantoinase; Validated; Region: PRK08323
699034010585	D-hydantoinases (D-HYD) also called dihydropyrimidases (DHPase) and related proteins; DHPases are a family of enzymes that catalyze the reversible hydrolytic ring opening of the amide bond in five- or six-membered cyclic diamides, like dihydropyrimidine...; Region: D-HYD; cd01314
699034010586	tetramer interface [polypeptide binding]; other site
699034010587	active site
699034010588	dihydropyrimidine dehydrogenase subunit B; Validated; Region: PRK08318
699034010589	Dihydroorotate dehydrogenase (DHOD) and Dihydropyrimidine dehydrogenase (DHPD) FMN-binding domain. DHOD catalyzes the oxidation of (S)-dihydroorotate to orotate. This is the fourth step and the only redox reaction in the de novo biosynthesis of UMP, the...; Region: DHOD_DHPD_FMN; cd02810
699034010590	active site
699034010591	FMN binding site [chemical binding]; other site
699034010592	substrate binding site [chemical binding]; other site
699034010593	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
699034010594	Sulfate transporter family; Region: Sulfate_transp; cl19250
699034010595	xanthine permease; Region: pbuX; TIGR03173
699034010596	putative chlorohydrolase/aminohydrolase; Validated; Region: PRK07203
699034010597	TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are...; Region: ATZ_TRZ_like; cd01298
699034010598	active site
699034010599	putative substrate binding pocket [chemical binding]; other site
699034010600	D-aminoacylases (N-acyl-D-Amino acid amidohydrolases) catalyze the hydrolysis of N-acyl-D-amino acids to produce the corresponding D-amino acids, which are used as intermediates in the synthesis of pesticides, bioactive peptides, and antibiotics; Region: D-aminoacylase; cd01297
699034010601	N-acyl-D-aspartate/D-glutamate deacylase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: COG3653
699034010602	active site
699034010603	putative substrate binding pocket [chemical binding]; other site
699034010604	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
699034010605	peptidase; Reviewed; Region: PRK13004
699034010606	M20 Peptidases with similarity to acetylornithine deacetylases and succinyl-diaminopimelate desuccinylases; Region: M20_ArgE_DapE_like4; cd05649
699034010607	putative metal binding site [ion binding]; other site
699034010608	putative dimer interface [polypeptide binding]; other site
699034010609	Pyridoxal-phosphate dependent enzyme; Region: PALP; pfam00291
699034010610	Tryptophan synthase beta superfamily (fold type II); this family of pyridoxal phosphate (PLP)-dependent enzymes catalyzes beta-replacement and beta-elimination reactions. This CD corresponds to aminocyclopropane-1-carboxylate deaminase (ACCD), tryptophan...; Region: Trp-synth-beta_II; cd00640
699034010611	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
699034010612	catalytic residue [active]
699034010613	2'-5' RNA ligase superfamily; Region: 2_5_RNA_ligase2; pfam13563
699034010614	GAF domain; Region: GAF; cl17456
699034010615	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034010616	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
699034010617	Walker A motif; other site
699034010618	ATP binding site [chemical binding]; other site
699034010619	Walker B motif; other site
699034010620	arginine finger; other site
699034010621	YjgF, YER057c, and UK114 belong to a large family of proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no...; Region: YjgF_YER057c_UK114_family; cd00448
699034010622	homotrimer interaction site [polypeptide binding]; other site
699034010623	putative active site [active]
699034010624	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
699034010625	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
699034010626	Helix-Turn-Helix DNA binding domain of the MerR-like transcription regulators YyaN and YraB; Region: HTH_YyaN; cd01109
699034010627	DNA binding residues [nucleotide binding]
699034010628	putative dimer interface [polypeptide binding]; other site
699034010629	Predicted oxidoreductases of the aldo/keto reductase family [General function prediction only]; Region: COG1453
699034010630	Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. AKRs are present in all phyla and are of importance to both health and industrial...; Region: Aldo_ket_red; cd06660
699034010631	active site
699034010632	catalytic tetrad [active]
699034010633	4Fe-4S dicluster domain; Region: Fer4_17; pfam13534
699034010634	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034010635	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034010636	Putative cell wall binding repeat 2; Region: CW_binding_2; pfam04122
699034010637	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
699034010638	Peptidase propeptide and YPEB domain; Region: PepSY; pfam03413
699034010639	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
699034010640	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
699034010641	Walker A/P-loop; other site
699034010642	ATP binding site [chemical binding]; other site
699034010643	Q-loop/lid; other site
699034010644	ABC transporter signature motif; other site
699034010645	Walker B; other site
699034010646	D-loop; other site
699034010647	H-loop/switch region; other site
699034010648	FtsX-like permease family; Region: FtsX; pfam02687
699034010649	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034010650	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034010651	ATP binding site [chemical binding]; other site
699034010652	Mg2+ binding site [ion binding]; other site
699034010653	G-X-G motif; other site
699034010654	Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: CitB; COG2197
699034010655	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034010656	active site
699034010657	phosphorylation site [posttranslational modification]
699034010658	intermolecular recognition site; other site
699034010659	dimerization interface [polypeptide binding]; other site
699034010660	C-terminal DNA-binding domain of LuxR-like proteins. This domain contains a helix-turn-helix motif and binds DNA. Proteins belonging to this group are response regulators; some act as transcriptional activators, others as transcriptional repressors. Many...; Region: LuxR_C_like; cd06170
699034010661	DNA binding residues [nucleotide binding]
699034010662	dimerization interface [polypeptide binding]; other site
699034010663	Homeodomain-like domain; Region: HTH_23; pfam13384
699034010664	Conserved phage C-terminus (Phg_2220_C); Region: Phg_2220_C; pfam09524
699034010665	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
699034010666	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
699034010667	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
699034010668	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
699034010669	Excinuclease ATPase subunit [DNA replication, recombination, and repair]; Region: UvrA; COG0178
699034010670	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
699034010671	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034010672	Walker A/P-loop; other site
699034010673	ATP binding site [chemical binding]; other site
699034010674	Q-loop/lid; other site
699034010675	ABC transporter signature motif; other site
699034010676	Walker B; other site
699034010677	D-loop; other site
699034010678	H-loop/switch region; other site
699034010679	Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms]; Region: AmpC; COG1680
699034010680	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
699034010681	First Helix-Turn-Helix DNA binding domain of the regulatory protein TioE; Region: HTH_TioE_rpt1; cd04772
699034010682	DNA binding residues [nucleotide binding]
699034010683	putative dimer interface [polypeptide binding]; other site
699034010684	Helix-Turn-Helix DNA binding domain of MerR-like transcription regulators; Region: HTH_MerR-like; cd00592
699034010685	DNA binding residues [nucleotide binding]
699034010686	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
699034010687	dimer interface [polypeptide binding]; other site
699034010688	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
699034010689	H+ Antiporter protein; Region: 2A0121; TIGR00900
699034010690	putative substrate translocation pore; other site
699034010691	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
699034010692	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
699034010693	Acyltransferase family; Region: Acyl_transf_3; cl19154
699034010694	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
699034010695	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
699034010696	Walker A/P-loop; other site
699034010697	ATP binding site [chemical binding]; other site
699034010698	Q-loop/lid; other site
699034010699	ABC transporter signature motif; other site
699034010700	Walker B; other site
699034010701	D-loop; other site
699034010702	H-loop/switch region; other site
699034010703	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034010704	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cd06225
699034010705	dimerization interface [polypeptide binding]; other site
699034010706	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034010707	dimer interface [polypeptide binding]; other site
699034010708	phosphorylation site [posttranslational modification]
699034010709	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034010710	ATP binding site [chemical binding]; other site
699034010711	Mg2+ binding site [ion binding]; other site
699034010712	G-X-G motif; other site
699034010713	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034010714	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034010715	active site
699034010716	phosphorylation site [posttranslational modification]
699034010717	intermolecular recognition site; other site
699034010718	dimerization interface [polypeptide binding]; other site
699034010719	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034010720	DNA binding site [nucleotide binding]
699034010721	60Kd inner membrane protein; Region: 60KD_IMP; pfam02096
699034010722	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514
699034010723	FMN binding site [chemical binding]; other site
699034010724	dimer interface [polypeptide binding]; other site
699034010725	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
699034010726	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
699034010727	Transcriptional regulators [Transcription]; Region: MarR; COG1846
699034010728	helix_turn_helix multiple antibiotic resistance protein; Region: HTH_MARR; smart00347
699034010729	Predicted transcriptional regulators [Transcription]; Region: COG1695
699034010730	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
699034010731	NADPH-dependent FMN reductase; Region: FMN_red; cl00438
699034010732	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
699034010733	S-adenosylmethionine binding site [chemical binding]; other site
699034010734	Protein of unknown function (DUF3781); Region: DUF3781; pfam12636
699034010735	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
699034010736	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
699034010737	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034010738	sulfate ABC transporter, ATP-binding protein; Region: 3a0106s01; TIGR00968
699034010739	Walker A/P-loop; other site
699034010740	ATP binding site [chemical binding]; other site
699034010741	Q-loop/lid; other site
699034010742	ABC transporter signature motif; other site
699034010743	Walker B; other site
699034010744	D-loop; other site
699034010745	H-loop/switch region; other site
699034010746	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034010747	dimer interface [polypeptide binding]; other site
699034010748	conserved gate region; other site
699034010749	putative PBP binding loops; other site
699034010750	ABC-ATPase subunit interface; other site
699034010751	Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) [Cell envelope biogenesis, outer membrane]; Region: OpuBC; COG1732
699034010752	Excinuclease ATPase subunit [DNA replication, recombination, and repair]; Region: UvrA; COG0178
699034010753	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
699034010754	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034010755	Walker A/P-loop; other site
699034010756	ATP binding site [chemical binding]; other site
699034010757	Q-loop/lid; other site
699034010758	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cl19048
699034010759	ABC transporter signature motif; other site
699034010760	Walker B; other site
699034010761	D-loop; other site
699034010762	H-loop/switch region; other site
699034010763	GlcNAc-PI de-N-acetylase; Region: PIG-L; pfam02585
699034010764	Hsp33-like chaperonin; Reviewed; Region: hslO; PRK00114
699034010765	Heat shock protein 33 (Hsp33):  Cytosolic protein that acts as a molecular chaperone under oxidative conditions.  In normal (reducing) cytosolic conditions, four conserved Cys residues are coordinated by a Zn ion. Under oxidative stress (such as heat...; Region: Hsp33; cd00498
699034010766	dimerization interface [polypeptide binding]; other site
699034010767	domain crossover interface; other site
699034010768	redox-dependent activation switch; other site
699034010769	SAM-dependent methyltransferases [Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only]; Region: SmtA; COG0500
699034010770	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
699034010771	S-adenosylmethionine binding site [chemical binding]; other site
699034010772	Histidine-specific methyltransferase, SAM-dependent; Region: Methyltransf_33; pfam10017
699034010773	Small, acid-soluble spore proteins, alpha/beta type; Region: SASP; pfam00269
699034010774	Metal-dependent amidase/aminoacylase/carboxypeptidase [General function prediction only]; Region: AbgB; COG1473
699034010775	M20 Peptidase Aminoacylase 1 family; Region: M20_Acy1; cd03886
699034010776	metal binding site [ion binding]; metal-binding site
699034010777	dimer interface [polypeptide binding]; other site
699034010778	L-serine dehydratase, iron-sulfur-dependent, single chain form; Region: sda_mono; TIGR00720
699034010779	Serine dehydratase beta chain; Region: SDH_beta; pfam03315
699034010780	Serine dehydratase alpha chain; Region: SDH_alpha; pfam03313
699034010781	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
699034010782	dimer interface [polypeptide binding]; other site
699034010783	active site
699034010784	catalytic residue [active]
699034010785	aspartate-semialdehyde dehydrogenase; Provisional; Region: PRK14874
699034010786	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; pfam01118
699034010787	Semialdehyde dehydrogenase, dimerization domain; Region: Semialdhyde_dhC; pfam02774
699034010788	Dihydrodipicolinate synthase (DHDPS); Region: DHDPS; cd00950
699034010789	dimer interface [polypeptide binding]; other site
699034010790	active site
699034010791	catalytic residue [active]
699034010792	dihydrodipicolinate reductase; Provisional; Region: PRK00048
699034010793	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
699034010794	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
699034010795	Tetrahydrodipicolinate succinyltransferase N-terminal; Region: DapH_N; pfam08503
699034010796	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-acetyltransferase; Region: DapD_Ac; TIGR03532
699034010797	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate (THDP) N-succinyltransferase (also called THP succinyltransferase): THDP N-succinyltransferase catalyzes the conversion of tetrahydrodipicolinate and succinyl-CoA to N-succinyltetrahydrodipicolinate and CoA; Region: LbH_THP_succinylT; cd03350
699034010798	active site
699034010799	trimer interface [polypeptide binding]; other site
699034010800	substrate binding site [chemical binding]; other site
699034010801	CoA binding site [chemical binding]; other site
699034010802	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
699034010803	putative CoA binding site [chemical binding]; other site
699034010804	putative trimer interface [polypeptide binding]; other site
699034010805	Uncharacterized family; SPFH (stomatin, prohibitin, flotillin, and HflK/C) superfamily; Region: SPFH_like_u2; cd03402
699034010806	prohibitin homologues; Region: PHB; smart00244
699034010807	dihydrodipicolinate reductase; Provisional; Region: PRK00048
699034010808	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
699034010809	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
699034010810	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
699034010811	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
699034010812	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
699034010813	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
699034010814	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
699034010815	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
699034010816	active site
699034010817	L-cysteine desulfidase [Amino acid transport and metabolism]; Region: COG3681
699034010818	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034010819	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
699034010820	Walker A motif; other site
699034010821	ATP binding site [chemical binding]; other site
699034010822	Walker B motif; other site
699034010823	arginine finger; other site
699034010824	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
699034010825	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
699034010826	single-stranded DNA-binding protein; Provisional; Region: PRK05813
699034010827	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
699034010828	dimer interface [polypeptide binding]; other site
699034010829	ssDNA binding site [nucleotide binding]; other site
699034010830	tetramer (dimer of dimers) interface [polypeptide binding]; other site
699034010831	Predicted permeases [General function prediction only]; Region: COG0730
699034010832	Sulfite exporter TauE/SafE; Region: TauE; pfam01925
699034010833	proline racemase; Provisional; Region: PRK13969
699034010834	hydroxyproline-2-epimerase; Provisional; Region: PRK13971; cl19687
699034010835	Glycine/sarcosine/betaine reductase component B subunits; Region: Gly_reductase; pfam09338
699034010836	Glycine/sarcosine/betaine reductase component B subunits; Region: Gly_reductase; pfam09338
699034010837	potential frameshift: common BLAST hit: gi|260688442|ref|YP_003219576.1| proline reductase
699034010838	Glycine/sarcosine/betaine reductase component B subunits; Region: Gly_reductase; pfam09338
699034010839	FOG: CBS domain [General function prediction only]; Region: COG0517
699034010840	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_13; cd04626
699034010841	Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains [Transcription / Signal transduction mechanisms]; Region: RocR; COG3829
699034010842	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034010843	Walker A motif; other site
699034010844	ATP binding site [chemical binding]; other site
699034010845	Walker B motif; other site
699034010846	arginine finger; other site
699034010847	Bacterial regulatory protein, Fis family; Region: HTH_8; pfam02954
699034010848	RnfC Barrel sandwich hybrid domain; Region: RnfC_N; pfam13375
699034010849	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
699034010850	SLBB domain; Region: SLBB; pfam10531
699034010851	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
699034010852	Small, acid-soluble spore proteins, alpha/beta type; Region: SASP; pfam00269
699034010853	Domain of unknown function (DUF4364); Region: DUF4364; pfam14277
699034010854	PQQ-dependent catabolism-associated beta-propeller protein; Region: PQQ_ABC_repeats; TIGR03866
699034010855	40-residue YVTN family beta-propeller repeat; Region: beta_rpt_yvtn; TIGR02276
699034010856	TSCPD domain; Region: TSCPD; cl14834
699034010857	Folylpolyglutamate synthase [Coenzyme metabolism]; Region: FolC; COG0285
699034010858	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
699034010859	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
699034010860	Peptidase S8 family domain, uncharacterized subfamily 8; Region: Peptidases_S8_8; cd07492
699034010861	Subtilase family; Region: Peptidase_S8; pfam00082
699034010862	active site
699034010863	catalytic triad [active]
699034010864	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
699034010865	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034010866	active site
699034010867	phosphorylation site [posttranslational modification]
699034010868	intermolecular recognition site; other site
699034010869	dimerization interface [polypeptide binding]; other site
699034010870	LytTr DNA-binding domain; Region: LytTR; smart00850
699034010871	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
699034010872	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
699034010873	active site
699034010874	HIGH motif; other site
699034010875	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
699034010876	KMSKS motif; other site
699034010877	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
699034010878	tRNA binding surface [nucleotide binding]; other site
699034010879	anticodon binding site; other site
699034010880	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
699034010881	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
699034010882	Catalytic NodB homology domain of the carbohydrate esterase 4 superfamily; Region: CE4_SF; cl15692
699034010883	[FeFe] hydrogenase, group B1/B3; Region: FeFe_hydrog_B1; TIGR04105
699034010884	Iron only hydrogenase large subunit, C-terminal domain; Region: Fe_hyd_lg_C; pfam02906
699034010885	Bacterial protein of unknown function (DUF939); Region: DUF939; pfam06081
699034010886	phosphate transport system regulatory protein PhoU; Region: phoU_full; TIGR02135
699034010887	PhoU domain; Region: PhoU; pfam01895
699034010888	PhoU domain; Region: PhoU; pfam01895
699034010889	phosphate transporter ATP-binding protein; Provisional; Region: PRK14240
699034010890	ATP-binding cassette domain of the phosphate transport system; Region: ABC_PstB_phosphate_transporter; cd03260
699034010891	Walker A/P-loop; other site
699034010892	ATP binding site [chemical binding]; other site
699034010893	Q-loop/lid; other site
699034010894	ABC transporter signature motif; other site
699034010895	Walker B; other site
699034010896	D-loop; other site
699034010897	H-loop/switch region; other site
699034010898	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstA; COG0581
699034010899	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034010900	dimer interface [polypeptide binding]; other site
699034010901	conserved gate region; other site
699034010902	putative PBP binding loops; other site
699034010903	ABC-ATPase subunit interface; other site
699034010904	ABC-type phosphate transport system, permease component [Inorganic ion transport and metabolism]; Region: PstC; COG0573
699034010905	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034010906	dimer interface [polypeptide binding]; other site
699034010907	conserved gate region; other site
699034010908	putative PBP binding loops; other site
699034010909	ABC-ATPase subunit interface; other site
699034010910	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
699034010911	ABC-2 family transporter protein; Region: ABC2_membrane_4; pfam12730
699034010912	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
699034010913	ABC-type multidrug transport system, ATPase component; Region: ABC_drug_resistance_like; cd03264
699034010914	Walker A/P-loop; other site
699034010915	ATP binding site [chemical binding]; other site
699034010916	Q-loop/lid; other site
699034010917	ABC transporter signature motif; other site
699034010918	Walker B; other site
699034010919	D-loop; other site
699034010920	H-loop/switch region; other site
699034010921	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034010922	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034010923	dimer interface [polypeptide binding]; other site
699034010924	phosphorylation site [posttranslational modification]
699034010925	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034010926	ATP binding site [chemical binding]; other site
699034010927	Mg2+ binding site [ion binding]; other site
699034010928	G-X-G motif; other site
699034010929	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034010930	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034010931	active site
699034010932	phosphorylation site [posttranslational modification]
699034010933	intermolecular recognition site; other site
699034010934	dimerization interface [polypeptide binding]; other site
699034010935	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034010936	DNA binding site [nucleotide binding]
699034010937	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034010938	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034010939	active site
699034010940	phosphorylation site [posttranslational modification]
699034010941	intermolecular recognition site; other site
699034010942	dimerization interface [polypeptide binding]; other site
699034010943	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034010944	DNA binding site [nucleotide binding]
699034010945	7TM diverse intracellular signalling; Region: 7TMR-DISM_7TM; cl09440
699034010946	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: COG3920
699034010947	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034010948	dimer interface [polypeptide binding]; other site
699034010949	phosphorylation site [posttranslational modification]
699034010950	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034010951	ATP binding site [chemical binding]; other site
699034010952	Mg2+ binding site [ion binding]; other site
699034010953	G-X-G motif; other site
699034010954	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034010955	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034010956	active site
699034010957	phosphorylation site [posttranslational modification]
699034010958	intermolecular recognition site; other site
699034010959	dimerization interface [polypeptide binding]; other site
699034010960	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034010961	DNA binding site [nucleotide binding]
699034010962	ABC transporter, phosphonate, periplasmic substrate-binding protein; Region: Phosphonate-bd; cl19131
699034010963	oligoendopeptidase F; Region: pepF; TIGR00181
699034010964	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
699034010965	active site
699034010966	Zn binding site [ion binding]; other site
699034010967	Uncharacterized membrane protein [Function unknown]; Region: SapB; COG1285
699034010968	MgtC family; Region: MgtC; pfam02308
699034010969	Heptaprenyl diphosphate synthase component I; Region: Hpre_diP_synt_I; pfam07456
699034010970	Fe2+ transport system protein A [Inorganic ion transport and metabolism]; Region: FeoA; COG1918
699034010971	Fe2+ transport system protein B [Inorganic ion transport and metabolism]; Region: FeoB; COG0370
699034010972	Ferrous iron transport protein B (FeoB) family; Region: FeoB; cd01879
699034010973	G1 box; other site
699034010974	GTP/Mg2+ binding site [chemical binding]; other site
699034010975	Switch I region; other site
699034010976	G2 box; other site
699034010977	G3 box; other site
699034010978	Switch II region; other site
699034010979	G4 box; other site
699034010980	G5 box; other site
699034010981	Nucleoside recognition; Region: Gate; pfam07670
699034010982	Ferrous iron transport protein B C terminus; Region: FeoB_C; pfam07664
699034010983	Nucleoside recognition; Region: Gate; pfam07670
699034010984	Virus attachment protein p12 family; Region: P12; pfam12669
699034010985	Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane]; Region: AgaS; COG2222
699034010986	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
699034010987	dimer interface [polypeptide binding]; other site
699034010988	active site
699034010989	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
699034010990	dimer interface [polypeptide binding]; other site
699034010991	active site
699034010992	PTS system mannose/fructose/sorbose family IID component; Region: EIID-AGA; pfam03613
699034010993	Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC [Carbohydrate transport and metabolism]; Region: ManY; COG3715
699034010994	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
699034010995	active pocket/dimerization site; other site
699034010996	active site
699034010997	phosphorylation site [posttranslational modification]
699034010998	PTS system sorbose subfamily IIB component; Region: PTSIIB_sorb; pfam03830
699034010999	active site
699034011000	phosphorylation site [posttranslational modification]
699034011001	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034011002	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
699034011003	Walker A motif; other site
699034011004	ATP binding site [chemical binding]; other site
699034011005	Walker B motif; other site
699034011006	arginine finger; other site
699034011007	Transcriptional antiterminator [Transcription]; Region: COG3933
699034011008	PTS_IIA, PTS system, mannose/sorbose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This family...; Region: PTS_IIA_man; cl00025
699034011009	active pocket/dimerization site; other site
699034011010	active site
699034011011	phosphorylation site [posttranslational modification]
699034011012	PRD domain; Region: PRD; pfam00874
699034011013	pyrroline-5-carboxylate reductase; Reviewed; Region: PRK11880
699034011014	NADP oxidoreductase coenzyme F420-dependent; Region: F420_oxidored; pfam03807
699034011015	Pyrroline-5-carboxylate reductase dimerization; Region: P5CR_dimer; pfam14748
699034011016	glycyl radical enzyme, PFL2/glycerol dehydratase family; Region: PFL2-3; TIGR01774
699034011017	Pyruvate formate lyase 2 and related enzymes; Region: PFL2_DhaB_BssA; cd01677
699034011018	dimer interface [polypeptide binding]; other site
699034011019	active site
699034011020	glycine loop; other site
699034011021	glycyl-radical enzyme activating protein family; Region: PFLE_PFLC; TIGR02494
699034011022	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
699034011023	DRE-TIM metallolyase superfamily; Region: DRE_TIM_metallolyase; cl18962
699034011024	periplasmic serine pepetdase DegS; Region: protease_degS; TIGR02038
699034011025	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
699034011026	PDZ domain of trypsin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
699034011027	protein binding site [polypeptide binding]; other site
699034011028	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14097
699034011029	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
699034011030	active site
699034011031	dimer interface [polypeptide binding]; other site
699034011032	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
699034011033	dimer interface [polypeptide binding]; other site
699034011034	active site
699034011035	Na+/phosphate symporter [Inorganic ion transport and metabolism]; Region: NptA; COG1283
699034011036	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
699034011037	Na+/Pi-cotransporter; Region: Na_Pi_cotrans; pfam02690
699034011038	PhoU domain; Region: PhoU; pfam01895
699034011039	PhoU domain; Region: PhoU; pfam01895
699034011040	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl19134
699034011041	SEC-C motif; Region: SEC-C; pfam02810
699034011042	Tfp pilus assembly protein, ATPase PilM [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PilM; COG4972
699034011043	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
699034011044	prepilin-type N-terminal cleavage/methylation domain; Region: IV_pilin_GFxxxE; TIGR02532
699034011045	potential frameshift: common BLAST hit: gi|260688497|ref|YP_003219631.1| type IV pilus-assembly protein
699034011046	Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulE; COG2804
699034011047	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
699034011048	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
699034011049	Walker A motif; other site
699034011050	ATP binding site [chemical binding]; other site
699034011051	Walker B motif; other site
699034011052	Sec1 family; Region: Sec1; cl15415
699034011053	Bacterial protein of unknown function (DUF881); Region: DUF881; pfam05949
699034011054	hypothetical protein; Provisional; Region: PRK06851
699034011055	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034011056	Walker A motif; other site
699034011057	ATP binding site [chemical binding]; other site
699034011058	Walker B motif; other site
699034011059	drug resistance transporter, EmrB/QacA subfamily; Region: efflux_EmrB; TIGR00711
699034011060	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
699034011061	putative substrate translocation pore; other site
699034011062	Predicted GTPase [General function prediction only]; Region: COG0218
699034011063	YihA (EngB) GTPase family; Region: YihA_EngB; cd01876
699034011064	G1 box; other site
699034011065	GTP/Mg2+ binding site [chemical binding]; other site
699034011066	Switch I region; other site
699034011067	G2 box; other site
699034011068	G3 box; other site
699034011069	Switch II region; other site
699034011070	G4 box; other site
699034011071	G5 box; other site
699034011072	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
699034011073	ATP-dependent protease La (LON) domain; Region: LON; pfam02190
699034011074	Biogenesis of lysosome-related organelles complex-1 subunit 2; Region: BLOC1_2; pfam10046
699034011075	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034011076	Walker A motif; other site
699034011077	ATP binding site [chemical binding]; other site
699034011078	Walker B motif; other site
699034011079	arginine finger; other site
699034011080	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
699034011081	Chromate transporter; Region: Chromate_transp; pfam02417
699034011082	Chromate transporter; Region: Chromate_transp; pfam02417
699034011083	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
699034011084	ClpX C4-type zinc finger; Region: zf-C4_ClpX; pfam06689
699034011085	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034011086	Walker A motif; other site
699034011087	ATP binding site [chemical binding]; other site
699034011088	Walker B motif; other site
699034011089	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
699034011090	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
699034011091	oligomer interface [polypeptide binding]; other site
699034011092	active site residues [active]
699034011093	trigger factor; Provisional; Region: tig; PRK01490
699034011094	Bacterial trigger factor protein (TF); Region: Trigger_N; pfam05697
699034011095	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
699034011096	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
699034011097	Escherichia coli YfcE and related proteins, metallophosphatase domain; Region: MPP_YfcE; cd00841
699034011098	active site
699034011099	metal binding site [ion binding]; metal-binding site
699034011100	homotetramer interface [polypeptide binding]; other site
699034011101	ribonuclease PH; Reviewed; Region: rph; PRK00173
699034011102	Ribonuclease PH; Region: RNase_PH_bact; cd11362
699034011103	hexamer interface [polypeptide binding]; other site
699034011104	active site
699034011105	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
699034011106	active site
699034011107	dimerization interface [polypeptide binding]; other site
699034011108	NAD-dependent DNA ligase LigA; Validated; Region: ligA; PRK07956
699034011109	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
699034011110	nucleotide binding pocket [chemical binding]; other site
699034011111	K-X-D-G motif; other site
699034011112	catalytic site [active]
699034011113	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
699034011114	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
699034011115	Helix-hairpin-helix domain; Region: HHH_5; pfam14520
699034011116	Helix-hairpin-helix motif; Region: HHH_2; pfam12826
699034011117	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
699034011118	Dimer interface [polypeptide binding]; other site
699034011119	BRCT sequence motif; other site
699034011120	Phosphoglycerate dehydrogenase and related dehydrogenases [Amino acid transport and metabolism]; Region: SerA; COG0111
699034011121	Phosphoglycerate Dehydrogenase, 2-hydroxyacid dehydrogenase family; Region: PGDH_1; cd12155
699034011122	putative ligand binding site [chemical binding]; other site
699034011123	NAD binding site [chemical binding]; other site
699034011124	catalytic site [active]
699034011125	Domain of unknown function (DUF3783); Region: DUF3783; pfam12646
699034011126	oxalate/formate antiporter family transporter; Region: 2A0111; TIGR00890
699034011127	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
699034011128	putative substrate translocation pore; other site
699034011129	Fe-S-cluster-containing hydrogenase components 2 [Energy production and conversion]; Region: HycB; COG1142
699034011130	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
699034011131	[FeFe] hydrogenase, group A; Region: FeFe_hydrog_A; TIGR02512
699034011132	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
699034011133	Iron only hydrogenase large subunit, C-terminal domain; Region: Fe_hyd_lg_C; pfam02906
699034011134	Iron hydrogenase small subunit; Region: Fe_hyd_SSU; pfam02256
699034011135	DMSO reductase, iron-sulfur subunit; Region: DMSO_dmsB; TIGR02951
699034011136	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
699034011137	FdhD/NarQ family; Region: FdhD-NarQ; pfam02634
699034011138	potential frameshift: common BLAST hit: gi|260688520|ref|YP_003219654.1| formate dehydrogenase h
699034011139	Uncharacterized protein family (UPF0104); Region: UPF0104; pfam03706
699034011140	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034011141	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034011142	active site
699034011143	phosphorylation site [posttranslational modification]
699034011144	intermolecular recognition site; other site
699034011145	dimerization interface [polypeptide binding]; other site
699034011146	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034011147	DNA binding site [nucleotide binding]
699034011148	Domain of unknown function (DUF3786); Region: DUF3786; pfam12654
699034011149	Prenyltransferase-like; Region: Prenyltrans_1; pfam13243
699034011150	This group contains class II terpene cyclases, protein prenyltransferases beta subunit, two broadly specific proteinase inhibitors alpha2-macroglobulin (alpha (2)-M) and pregnancy zone protein (PZP) and, the C3 C4 and C5 components of vertebrate...; Region: ISOPREN_C2_like; cl08267
699034011151	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
699034011152	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034011153	Walker A/P-loop; other site
699034011154	ATP binding site [chemical binding]; other site
699034011155	Q-loop/lid; other site
699034011156	ABC transporter signature motif; other site
699034011157	Walker B; other site
699034011158	D-loop; other site
699034011159	H-loop/switch region; other site
699034011160	Accessory gene regulator B; Region: AgrB; pfam04647
699034011161	cyclic lactone autoinducer peptide; Region: quorum_AgrD; TIGR04223
699034011162	Predicted signal transduction protein with a C-terminal ATPase domain [Signal transduction mechanisms]; Region: COG2972
699034011163	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034011164	ATP binding site [chemical binding]; other site
699034011165	Mg2+ binding site [ion binding]; other site
699034011166	G-X-G motif; other site
699034011167	Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms]; Region: LytT; COG3279
699034011168	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034011169	active site
699034011170	phosphorylation site [posttranslational modification]
699034011171	intermolecular recognition site; other site
699034011172	dimerization interface [polypeptide binding]; other site
699034011173	LytTr DNA-binding domain; Region: LytTR; smart00850
699034011174	Protein of unknown function (DUF1062); Region: DUF1062; pfam06353
699034011175	Mor transcription activator family; Region: Mor; cl02360
699034011176	Uncharacterized Fe-S protein [Energy production and conversion]; Region: COG1600
699034011177	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
699034011178	Collagen triple helix repeat (20 copies); Region: Collagen; pfam01391
699034011179	BclB C-terminal domain; Region: exospore_TM; TIGR03721
699034011180	Glycosyltransferases involved in cell wall biogenesis [Cell envelope biogenesis, outer membrane]; Region: WcaA; COG0463
699034011181	UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide; Region: Beta4Glucosyltransferase; cd02511
699034011182	putative metal binding site; other site
699034011183	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
699034011184	binding surface
699034011185	TPR motif; other site
699034011186	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
699034011187	oligomer interface [polypeptide binding]; other site
699034011188	active site residues [active]
699034011189	Bacterial regulatory helix-turn-helix proteins, AraC family; Region: HTH_AraC; pfam00165
699034011190	helix_turn_helix, arabinose operon control protein; Region: HTH_ARAC; smart00342
699034011191	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs [Transcription / Amino acid transport and metabolism]; Region: ARO8; COG1167
699034011192	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
699034011193	DNA-binding site [nucleotide binding]; DNA binding site
699034011194	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
699034011195	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034011196	homodimer interface [polypeptide binding]; other site
699034011197	catalytic residue [active]
699034011198	B3/4 domain; Region: B3_4; cl19243
699034011199	Nitroreductase-like family 3. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and...; Region: Nitroreductase_3; cd02139
699034011200	putative FMN binding site [chemical binding]; other site
699034011201	Predicted transcriptional regulators [Transcription]; Region: COG1733
699034011202	DJ-1 family protein; Region: not_thiJ; TIGR01383
699034011203	Type 1 glutamine amidotransferase (GATase1)-like domain found in Human DJ-1; Region: GATase1_DJ-1; cd03135
699034011204	conserved cys residue [active]
699034011205	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
699034011206	AsnC family; Region: AsnC_trans_reg; pfam01037
699034011207	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
699034011208	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
699034011209	ABC transporter; Region: ABC_tran_2; pfam12848
699034011210	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
699034011211	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034011212	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034011213	active site
699034011214	phosphorylation site [posttranslational modification]
699034011215	intermolecular recognition site; other site
699034011216	dimerization interface [polypeptide binding]; other site
699034011217	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034011218	DNA binding site [nucleotide binding]
699034011219	Na+-driven multidrug efflux pump [Defense mechanisms]; Region: NorM; COG0534
699034011220	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Streptococcus aureus MepA; Region: MATE_MepA_like; cd13143
699034011221	ABC-2 family transporter protein; Region: ABC2_membrane_6; cl01496
699034011222	ABC-2 type transporter; Region: ABC2_membrane; cl17235
699034011223	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
699034011224	ABC-type uncharacterized transport system, ATPase component [General function prediction only]; Region: COG4586
699034011225	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034011226	Walker A/P-loop; other site
699034011227	ATP binding site [chemical binding]; other site
699034011228	Q-loop/lid; other site
699034011229	ABC transporter signature motif; other site
699034011230	Walker B; other site
699034011231	D-loop; other site
699034011232	H-loop/switch region; other site
699034011233	Nuclear transport factor 2 (NTF2-like) superfamily. This family includes members of the NTF2 family, Delta-5-3-ketosteroid isomerases, Scytalone Dehydratases, and the beta subunit of Ring hydroxylating dioxygenases. This family is a classic example of...; Region: NTF2_like; cl09109
699034011234	Diguanylate-cyclase (DGC) or GGDEF domain; Region: GGDEF; cd01949
699034011235	metal binding site [ion binding]; metal-binding site
699034011236	active site
699034011237	I-site; other site
699034011238	Transglutaminase-like superfamily; Region: Transglut_core; cl17362
699034011239	GTPase RsgA; Reviewed; Region: PRK01889
699034011240	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
699034011241	RNA binding site [nucleotide binding]; other site
699034011242	Ribosomal interacting GTPase YjeQ/EngC, a circularly permuted subfamily of the Ras GTPases; Region: YjeQ_EngC; cd01854
699034011243	GTPase/Zn-binding domain interface [polypeptide binding]; other site
699034011244	GTP/Mg2+ binding site [chemical binding]; other site
699034011245	G4 box; other site
699034011246	G5 box; other site
699034011247	G1 box; other site
699034011248	Switch I region; other site
699034011249	G2 box; other site
699034011250	G3 box; other site
699034011251	Switch II region; other site
699034011252	RNHCP domain; Region: RNHCP; pfam12647
699034011253	SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmA; COG2265
699034011254	TRAM domain; Region: TRAM; cl01282
699034011255	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
699034011256	S-adenosylmethionine binding site [chemical binding]; other site
699034011257	pyruvate kinase; Provisional; Region: PRK06354
699034011258	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cd00288
699034011259	domain interfaces; other site
699034011260	active site
699034011261	PEP-utilizing enzyme, mobile domain; Region: PEP-utilizers; cl17700
699034011262	6-phosphofructokinase; Provisional; Region: PRK03202
699034011263	active site
699034011264	ADP/pyrophosphate binding site [chemical binding]; other site
699034011265	dimerization interface [polypeptide binding]; other site
699034011266	allosteric effector site; other site
699034011267	fructose-1,6-bisphosphate binding site; other site
699034011268	DNA polymerase III DnaE; Reviewed; Region: dnaE; PRK06826
699034011269	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
699034011270	active site
699034011271	PHP Thumb interface [polypeptide binding]; other site
699034011272	metal binding site [ion binding]; metal-binding site
699034011273	Bacterial DNA polymerase III alpha subunit; Region: DNA_pol3_alpha; pfam07733
699034011274	Helix-hairpin-helix motif; Region: HHH_6; pfam14579
699034011275	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
699034011276	generic binding surface II; other site
699034011277	generic binding surface I; other site
699034011278	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1481
699034011279	WhiA N-terminal LAGLIDADG-like domain; Region: WhiA_N; pfam10298
699034011280	WhiA LAGLIDADG-like domain; Region: LAGLIDADG_WhiA; pfam14527
699034011281	WhiA C-terminal HTH domain; Region: HTH_WhiA; pfam02650
699034011282	Diadenosine hexaphosphate (Ap6A) hydrolase is a member of the Nudix hydrolase superfamily. Ap6A hydrolase specifically hydrolyzes diadenosine polyphosphates, but not ATP or diadenosine triphosphate, and it generates ATP as the product. Ap6A, the most...; Region: Ap6A_hydrolase; cd03673
699034011283	active site
699034011284	Ap6A binding site [chemical binding]; other site
699034011285	nudix motif; other site
699034011286	metal binding site [ion binding]; metal-binding site
699034011287	family of mostly uncharacterized proteins similar to B.subtilis YvcK; Region: YvcK_like; cd07187
699034011288	phosphate binding site [ion binding]; other site
699034011289	putative substrate binding pocket [chemical binding]; other site
699034011290	dimer interface [polypeptide binding]; other site
699034011291	glmZ(sRNA)-inactivating NTPase; Provisional; Region: PRK05416
699034011292	Polymerase and Histidinol Phosphatase domain; Region: PHP; cl17102
699034011293	Histidinol phosphatase and related hydrolases of the PHP family [Amino acid transport and metabolism / General function prediction only]; Region: HIS2; COG1387
699034011294	active site
699034011295	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
699034011296	FAD binding domain; Region: FAD_binding_4; pfam01565
699034011297	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
699034011298	Formate/nitrite transporter; Region: Form_Nir_trans; pfam01226
699034011299	Phospholipase_D-nuclease N-terminal; Region: PLDc_N; pfam13396
699034011300	cardiolipin synthase; Region: bac_cardiolipin; TIGR04265
699034011301	Catalytic domain, repeat 1, of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_1; cd09110
699034011302	putative active site [active]
699034011303	catalytic site [active]
699034011304	catalytic domain repeat 2 of bacterial cardiolipin synthase and similar proteins; Region: PLDc_CLS_2; cd09112
699034011305	putative active site [active]
699034011306	catalytic site [active]
699034011307	Thioredoxin-like [2Fe-2S] ferredoxin; Region: 2Fe-2S_thioredx; pfam01257
699034011308	TRX-like [2Fe-2S] Ferredoxin (Fd) family, NADH:ubiquinone oxidoreductase (Nuo) subunit E subfamily; Nuo, also called respiratory chain Complex 1, is the entry point for electrons into the respiratory chains of bacteria and the mitochondria of eukaryotes; Region: TRX_Fd_NuoE; cd03064
699034011309	putative dimer interface [polypeptide binding]; other site
699034011310	[2Fe-2S] cluster binding site [ion binding]; other site
699034011311	Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:...; Region: TRX_Fd_family; cd02980
699034011312	dimer interface [polypeptide binding]; other site
699034011313	[2Fe-2S] cluster binding site [ion binding]; other site
699034011314	NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion]; Region: NuoF; COG1894
699034011315	Respiratory-chain NADH dehydrogenase 51 Kd subunit; Region: Complex1_51K; pfam01512
699034011316	SLBB domain; Region: SLBB; pfam10531
699034011317	NADH-ubiquinone oxidoreductase-F iron-sulfur binding region; Region: NADH_4Fe-4S; smart00928
699034011318	The HCP family of iron-sulfur proteins includes hybrid cluster protein (HCP), acetyl-CoA synthase (ACS), and carbon monoxide dehydrogenase (CODH), all of which contain [Fe4-S4] metal clusters at their active sites. These proteins have a conserved...; Region: HCP_like; cl19102
699034011319	4Fe-4S dicluster domain; Region: Fer4_7; pfam12838
699034011320	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
699034011321	catalytic loop [active]
699034011322	iron binding site [ion binding]; other site
699034011323	NADH-ubiquinone oxidoreductase-G iron-sulfur binding region; Region: NADH-G_4Fe-4S_3; pfam10588
699034011324	[FeFe] hydrogenase, group A; Region: FeFe_hydrog_A; TIGR02512
699034011325	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
699034011326	Iron only hydrogenase large subunit, C-terminal domain; Region: Fe_hyd_lg_C; pfam02906
699034011327	Iron hydrogenase small subunit; Region: Fe_hyd_SSU; pfam02256
699034011328	Mismatch repair ATPase (MutS family) [DNA replication, recombination, and repair]; Region: MutS; COG0249
699034011329	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034011330	Walker A/P-loop; other site
699034011331	ATP binding site [chemical binding]; other site
699034011332	Q-loop/lid; other site
699034011333	ABC transporter signature motif; other site
699034011334	Walker B; other site
699034011335	D-loop; other site
699034011336	H-loop/switch region; other site
699034011337	HPr Serine kinase N terminus; Region: Hpr_kinase_N; pfam02603
699034011338	HPr kinase/phosphorylase; Provisional; Region: PRK05428
699034011339	HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent...; Region: HprK_C; cd01918
699034011340	Hpr binding site; other site
699034011341	active site
699034011342	homohexamer subunit interaction site [polypeptide binding]; other site
699034011343	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
699034011344	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
699034011345	GIY-YIG motif/motif A; other site
699034011346	active site
699034011347	catalytic site [active]
699034011348	putative DNA binding site [nucleotide binding]; other site
699034011349	metal binding site [ion binding]; metal-binding site
699034011350	UvrB/uvrC motif; Region: UVR; pfam02151
699034011351	SPRY domain; Region: SPRY; cl02614
699034011352	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
699034011353	Helix-hairpin-helix motif; Region: HHH_2; pfam12826
699034011354	excinuclease ABC subunit A; Reviewed; Region: uvrA; PRK00349
699034011355	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
699034011356	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
699034011357	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
699034011358	excinuclease ABC subunit B; Provisional; Region: PRK05298
699034011359	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
699034011360	ATP binding site [chemical binding]; other site
699034011361	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
699034011362	nucleotide binding region [chemical binding]; other site
699034011363	ATP-binding site [chemical binding]; other site
699034011364	Ultra-violet resistance protein B; Region: UvrB; pfam12344
699034011365	UvrB/uvrC motif; Region: UVR; pfam02151
699034011366	Uncharacterized proteins of the AP superfamily [General function prediction only]; Region: COG1524
699034011367	Type I phosphodiesterase / nucleotide pyrophosphatase; Region: Phosphodiest; pfam01663
699034011368	Maltose-binding periplasmic proteins/domains [Carbohydrate transport and metabolism]; Region: MalE; COG2182
699034011369	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
699034011370	ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism]; Region: UgpE; COG0395
699034011371	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034011372	dimer interface [polypeptide binding]; other site
699034011373	conserved gate region; other site
699034011374	putative PBP binding loops; other site
699034011375	ABC-ATPase subunit interface; other site
699034011376	ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism]; Region: PotC; COG1177
699034011377	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034011378	dimer interface [polypeptide binding]; other site
699034011379	conserved gate region; other site
699034011380	putative PBP binding loops; other site
699034011381	ABC-ATPase subunit interface; other site
699034011382	ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism]; Region: MalK; COG3839
699034011383	The N-terminal ATPase domain of the maltose transporter, MalK; Region: ABC_MalK_N; cd03301
699034011384	Walker A/P-loop; other site
699034011385	ATP binding site [chemical binding]; other site
699034011386	Q-loop/lid; other site
699034011387	ABC transporter signature motif; other site
699034011388	Walker B; other site
699034011389	D-loop; other site
699034011390	H-loop/switch region; other site
699034011391	potential RNA of insufficient length (23S ribosomal RNA)
699034011392	precorrin-2 dehydrogenase; Reviewed; Region: PRK06718
699034011393	Putative NAD(P)-binding; Region: NAD_binding_7; pfam13241
699034011394	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS; cd00384
699034011395	dimer interface [polypeptide binding]; other site
699034011396	active site
699034011397	Schiff base residues; other site
699034011398	Uroporphyrin-III C-methyltransferase (S-Adenosyl-L-methionine:uroporphyrinogen III methyltransferase, SUMT); Region: SUMT; cd11642
699034011399	active site
699034011400	SAM binding site [chemical binding]; other site
699034011401	homodimer interface [polypeptide binding]; other site
699034011402	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
699034011403	active site
699034011404	porphobilinogen deaminase; Reviewed; Region: hemC; PRK00072
699034011405	Hydroxymethylbilane synthase (HMBS), also known as porphobilinogen deaminase (PBGD), is an intermediate enzyme in the biosynthetic pathway of tetrapyrrolic ring systems, such as heme, chlorophylls, and vitamin B12. HMBS catalyzes the conversion of...; Region: HMBS; cd00494
699034011406	domain interfaces; other site
699034011407	active site
699034011408	Cobalt chelatase (CbiK); Region: CbiK; pfam06180
699034011409	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), N-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_N; cd03412
699034011410	active site
699034011411	C-terminal domain interface [polypeptide binding]; other site
699034011412	Anaerobic cobalamin biosynthetic cobalt chelatase (CbiK), C-terminal domain. CbiK is part of the cobalt-early path for cobalamin biosynthesis. It catalyzes the insertion of cobalt into the oxidized form of precorrin-2, factor II (sirohydrochlorin), the...; Region: CbiK_C; cd03413
699034011413	active site
699034011414	N-terminal domain interface [polypeptide binding]; other site
699034011415	Precorrin-2 C20-methyltransferase, also named CobI or CbiL; Region: Precorrin_2_C20_MT; cd11645
699034011416	active site
699034011417	SAM binding site [chemical binding]; other site
699034011418	homodimer interface [polypeptide binding]; other site
699034011419	Precorrin-6x reductase CbiJ/CobK; Region: CbiJ; cl00922
699034011420	Precorrin-3B C(17)-methyltransferase (CobJ/CbiH); Region: Precorrin_3B_C17_MT; cd11646
699034011421	active site
699034011422	SAM binding site [chemical binding]; other site
699034011423	homodimer interface [polypeptide binding]; other site
699034011424	cobalamin biosynthesis protein CbiG; Validated; Region: PRK05788
699034011425	Cobalamin synthesis G N-terminal; Region: CbiG_N; pfam11760
699034011426	Cobalamin biosynthesis central region; Region: CbiG_mid; pfam11761
699034011427	Cobalamin synthesis G C-terminus; Region: CbiG_C; pfam01890
699034011428	Precorrin-4 C11-methyltransferase (CbiF/CobM); Region: Precorrin-4_C11-MT; cd11641
699034011429	active site
699034011430	SAM binding site [chemical binding]; other site
699034011431	homodimer interface [polypeptide binding]; other site
699034011432	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
699034011433	S-adenosylmethionine binding site [chemical binding]; other site
699034011434	Precorrin-6Y methyltransferase, the cobalamin biosynthesis enzyme CbiE; Region: Precorrin-6Y-methylase; cd11644
699034011435	active site
699034011436	putative homodimer interface [polypeptide binding]; other site
699034011437	SAM binding site [chemical binding]; other site
699034011438	cobalt-precorrin-6A synthase; Reviewed; Region: cbiD; PRK00075
699034011439	cobalt-precorrin-8X methylmutase; Validated; Region: cbiC; PRK08286
699034011440	Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase [Secondary metabolites biosynthesis, transport, and catabolism]; Region: PduX; COG4542
699034011441	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
699034011442	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
699034011443	L-threonine-O-3-phosphate decarboxylase; Region: L_thr_O3P_dcar; TIGR01140
699034011444	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
699034011445	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034011446	homodimer interface [polypeptide binding]; other site
699034011447	catalytic residue [active]
699034011448	CobD/Cbib protein; Region: CobD_Cbib; pfam03186
699034011449	cobyrinic acid a,c-diamide synthase; Validated; Region: PRK01077
699034011450	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cd01983
699034011451	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyrinic Acid a,c-Diamide Synthase; Region: GATase1_CobB; cd03130
699034011452	catalytic triad [active]
699034011453	cobyric acid synthase; Provisional; Region: PRK00784
699034011454	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
699034011455	Type 1 glutamine amidotransferase (GATase1) domain found in Cobyric Acid Synthase (CobQ); Region: GATase1_CobQ; cd01750
699034011456	catalytic triad [active]
699034011457	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
699034011458	catalytic core [active]
699034011459	cobalamin synthase; Reviewed; Region: cobS; PRK00235
699034011460	Adenosylcobinamide kinase / adenosylcobinamide phosphate guanyltransferase (CobU). CobU is bifunctional cobalbumin biosynthesis enzymes which display adenosylcobinamide kinase and adenosylcobinamide phosphate guanyltransferase activity. This enzyme is a...; Region: CobU; cd00544
699034011461	homotrimer interface [polypeptide binding]; other site
699034011462	Walker A motif; other site
699034011463	GTP binding site [chemical binding]; other site
699034011464	Walker B motif; other site
699034011465	Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Region: DMB-PRT_CobT; cd02439
699034011466	putative dimer interface [polypeptide binding]; other site
699034011467	active site pocket [active]
699034011468	putative cataytic base [active]
699034011469	Aldose 1-epimerase, similar to Lactococcus lactis lacX; Region: Aldose_epim_lacX; cd09024
699034011470	active site
699034011471	catalytic residues [active]
699034011472	putative C-S lyase; Region: C_S_lyase_PatB; TIGR04350
699034011473	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
699034011474	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034011475	homodimer interface [polypeptide binding]; other site
699034011476	catalytic residue [active]
699034011477	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
699034011478	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
699034011479	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
699034011480	active site
699034011481	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
699034011482	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
699034011483	active site
699034011484	P-loop; other site
699034011485	phosphorylation site [posttranslational modification]
699034011486	methionine cluster; other site
699034011487	PTS system, Lactose/Cellobiose specific IIA subunit; Region: PTS_IIA; pfam02255
699034011488	active site
699034011489	phosphorylation site [posttranslational modification]
699034011490	metal binding site [ion binding]; metal-binding site
699034011491	M42 Peptidase, Endoglucanases; Region: M42_Frv; cd05656
699034011492	oligomer interface [polypeptide binding]; other site
699034011493	active site
699034011494	metal binding site [ion binding]; metal-binding site
699034011495	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
699034011496	HTH domain; Region: HTH_11; pfam08279
699034011497	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG4399; cl19827
699034011498	PRD domain; Region: PRD; pfam00874
699034011499	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
699034011500	active site
699034011501	P-loop; other site
699034011502	phosphorylation site [posttranslational modification]
699034011503	Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2; Region: PTS_EIIA_2; pfam00359
699034011504	active site
699034011505	phosphorylation site [posttranslational modification]
699034011506	Tagatose-1,6-bisphosphate (TBP) aldolase and related Type B Class II aldolases. TBP aldolase is a tetrameric class II aldolase that catalyzes the reversible condensation of dihydroxyacetone phosphate with glyceraldehyde 3-phsophate to produce tagatose 1; Region: TBP_aldolase_IIB; cd00947
699034011507	intersubunit interface [polypeptide binding]; other site
699034011508	active site
699034011509	zinc binding site [ion binding]; other site
699034011510	Na+ binding site [ion binding]; other site
699034011511	putative sugar isomerase, AgaS family; Region: agaS_fam; TIGR02815
699034011512	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
699034011513	dimer interface [polypeptide binding]; other site
699034011514	active site
699034011515	AgaS-like protein. AgaS contains a SIS (Sugar ISomerase) domain which is found in many phosphosugar isomerases and phosphosugar binding proteins. AgaS is a putative isomerase in Escherichia coli. It is similar to the glucosamine-6-phosphate synthases; Region: SIS_AgaS_like; cd05010
699034011516	putative active site [active]
699034011517	Predicted dehydrogenases and related proteins [General function prediction only]; Region: MviM; COG0673
699034011518	Oxidoreductase family, NAD-binding Rossmann fold; Region: GFO_IDH_MocA; pfam01408
699034011519	1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose...; Region: FruK_PfkB_like; cd01164
699034011520	putative substrate binding site [chemical binding]; other site
699034011521	putative ATP binding site [chemical binding]; other site
699034011522	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
699034011523	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
699034011524	DNA-binding site [nucleotide binding]; DNA binding site
699034011525	UTRA domain; Region: UTRA; pfam07702
699034011526	N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism]; Region: NagA; COG1820
699034011527	N-acetylglucosamine-6-phosphate deacetylase, NagA, catalyzes the hydrolysis of the N-acetyl group of N-acetyl-glucosamine-6-phosphate (GlcNAc-6-P) to glucosamine 6-phosphate and acetate. This is the first committed step in the biosynthetic pathway to...; Region: NagA; cd00854
699034011528	active site
699034011529	dimer interface [polypeptide binding]; other site
699034011530	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
699034011531	Transposase, Mutator family; Region: Transposase_mut; cl19537
699034011532	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
699034011533	Transposase, Mutator family; Region: Transposase_mut; cl19537
699034011534	Putative amidase domain; Region: Amidase_6; pfam12671
699034011535	Fic family protein [Function unknown]; Region: COG3177
699034011536	Fic/DOC family; Region: Fic; pfam02661
699034011537	transcriptional regulator EutR; Provisional; Region: PRK10130
699034011538	multiple promoter invertase; Provisional; Region: mpi; PRK13413
699034011539	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
699034011540	catalytic residues [active]
699034011541	catalytic nucleophile [active]
699034011542	Presynaptic Site I dimer interface [polypeptide binding]; other site
699034011543	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
699034011544	Synaptic Flat tetramer interface [polypeptide binding]; other site
699034011545	Synaptic Site I dimer interface [polypeptide binding]; other site
699034011546	DNA binding site [nucleotide binding]
699034011547	potential frameshift: common BLAST hit: gi|302389842|ref|YP_003825663.1| phage protein
699034011548	potential frameshift: common BLAST hit: gi|302389842|ref|YP_003825663.1| phage protein
699034011549	Phage portal protein, SPP1 Gp6-like; Region: Phage_prot_Gp6; pfam05133
699034011550	phage portal protein, SPP1 family; Region: portal_SPP1; TIGR01538
699034011551	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cl02713
699034011552	Domain of unknown function (DUF4367); Region: DUF4367; pfam14285
699034011553	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
699034011554	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
699034011555	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
699034011556	DNA binding residues [nucleotide binding]
699034011557	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG3328
699034011558	Transposase, Mutator family; Region: Transposase_mut; cl19537
699034011559	C-terminal peptidase (prc); Region: prc; TIGR00225
699034011560	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
699034011561	protein binding site [polypeptide binding]; other site
699034011562	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
699034011563	Catalytic dyad [active]
699034011564	5,10-methenyltetrahydrofolate synthetase; Region: MTHFS_bact; TIGR02727
699034011565	Solute carrier families 5 and 6-like; solute binding domain; Region: SLC5-6-like_sbd; cl00456
699034011566	Transketolase, C-terminal subunit [Carbohydrate transport and metabolism]; Region: COG3958
699034011567	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
699034011568	PYR/PP interface [polypeptide binding]; other site
699034011569	dimer interface [polypeptide binding]; other site
699034011570	TPP binding site [chemical binding]; other site
699034011571	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
699034011572	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
699034011573	TPP-binding site [chemical binding]; other site
699034011574	dimer interface [polypeptide binding]; other site
699034011575	PemK-like protein; Region: PemK; pfam02452
699034011576	Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain [Transcription]; Region: NikR; COG0864
699034011577	Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase; Region: PLPDE_III_AR; cd00430
699034011578	alanine racemase; Reviewed; Region: alr; PRK00053
699034011579	active site
699034011580	pyridoxal 5'-phosphate (PLP) binding site [chemical binding]; other site
699034011581	dimer interface [polypeptide binding]; other site
699034011582	substrate binding site [chemical binding]; other site
699034011583	catalytic residues [active]
699034011584	Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane]; Region: LolA; COG2834
699034011585	FOG: CBS domain [General function prediction only]; Region: COG0517
699034011586	The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called...; Region: CBS_pair_23; cd04636
699034011587	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
699034011588	mitochondrial ATP synthase delta subunit; Region: F1-ATPase_delta; cd12152
699034011589	gamma subunit interface [polypeptide binding]; other site
699034011590	epsilon subunit interface [polypeptide binding]; other site
699034011591	LBP interface [polypeptide binding]; other site
699034011592	F0F1 ATP synthase subunit beta; Validated; Region: PRK09280
699034011593	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
699034011594	F1 ATP synthase beta subunit, nucleotide-binding domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a...; Region: F1-ATPase_beta; cd01133
699034011595	alpha subunit interaction interface [polypeptide binding]; other site
699034011596	Walker A motif; other site
699034011597	ATP binding site [chemical binding]; other site
699034011598	Walker B motif; other site
699034011599	inhibitor binding site; inhibition site
699034011600	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
699034011601	mitochondrial ATP synthase gamma subunit; Region: F1-ATPase_gamma; cd12151
699034011602	core domain interface [polypeptide binding]; other site
699034011603	delta subunit interface [polypeptide binding]; other site
699034011604	epsilon subunit interface [polypeptide binding]; other site
699034011605	F0F1 ATP synthase subunit alpha; Validated; Region: PRK09281
699034011606	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
699034011607	F1 ATP synthase alpha, central domain. The F-ATPase is found in bacterial plasma membranes, mitochondrial inner membranes and in chloroplast thylakoid membranes. It has also been found in the archaea Methanosarcina barkeri. It uses a proton gradient to...; Region: F1_ATPase_alpha; cd01132
699034011608	beta subunit interaction interface [polypeptide binding]; other site
699034011609	Walker A motif; other site
699034011610	ATP binding site [chemical binding]; other site
699034011611	Walker B motif; other site
699034011612	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
699034011613	ATP synthase delta (OSCP) subunit; Region: OSCP; pfam00213
699034011614	F0F1 ATP synthase subunit B; Provisional; Region: PRK14473
699034011615	Apolipophorin-III and similar insect proteins; Region: ApoLp-III_like; cl19113
699034011616	F0F1 ATP synthase subunit C; Provisional; Region: PRK13469
699034011617	F0F1 ATP synthase subunit A; Validated; Region: PRK05815
699034011618	ATP synthase I chain; Region: ATP_synt_I; pfam03899
699034011619	Putative F0F1-ATPase subunit (ATPase_gene1); Region: ATPase_gene1; pfam09527
699034011620	Deoxycytidylate deaminase domain. Deoxycytidylate deaminase catalyzes the deamination of dCMP to dUMP, providing the nucleotide substrate for thymidylate synthase. The enzyme binds Zn++, which is required for catalytic activity. The activity of the...; Region: deoxycytidylate_deaminase; cd01286
699034011621	catalytic motif [active]
699034011622	Zn binding site [ion binding]; other site
699034011623	Biotinyl_lipoyl_domains are present in biotin-dependent carboxylases/decarboxylases, the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases, and the H-protein of the glycine cleavage system (GCS). These domains transport CO2, acyl; Region: Biotinyl_lipoyl_domains; cl11404
699034011624	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
699034011625	active site
699034011626	Ribose/Galactose Isomerase; Region: LacAB_rpiB; pfam02502
699034011627	Low molecular weight phosphatase family; Region: LMWPc; cd00115
699034011628	active site
699034011629	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
699034011630	Putative GTP-binding controlling metal-binding; Region: SUA5; pfam03481
699034011631	ZIP Zinc transporter; Region: Zip; cl00437
699034011632	peptide chain release factor 1; Validated; Region: prfA; PRK00591
699034011633	This domain is found in peptide chain release factors; Region: PCRF; smart00937
699034011634	RF-1 domain; Region: RF-1; pfam00472
699034011635	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
699034011636	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cl17173
699034011637	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
699034011638	S-adenosylmethionine binding site [chemical binding]; other site
699034011639	Protein of unknown function (DUF1385); Region: DUF1385; pfam07136
699034011640	50S ribosomal protein L31; Reviewed; Region: rpmE; PRK00019
699034011641	Protein predicted to be involved in meiotic recombination [Cell division and chromosome partitioning / General function prediction only]; Region: COG5124
699034011642	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
699034011643	transcription termination factor Rho; Provisional; Region: PRK12608
699034011644	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
699034011645	RNA binding site [nucleotide binding]; other site
699034011646	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
699034011647	multimer interface [polypeptide binding]; other site
699034011648	Walker A motif; other site
699034011649	ATP binding site [chemical binding]; other site
699034011650	Walker B motif; other site
699034011651	Prokaryotic UGPase catalyses the synthesis of UDP-glucose; Region: UGPase_prokaryotic; cd02541
699034011652	dTDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]; Region: RfbA; COG1209
699034011653	active site
699034011654	tetramer interface; other site
699034011655	oligoendopeptidase F; Region: pepF; TIGR00181
699034011656	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
699034011657	active site
699034011658	Zn binding site [ion binding]; other site
699034011659	stage II sporulation protein E; Region: spore_II_E; TIGR02865
699034011660	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
699034011661	Sigma factor PP2C-like phosphatases; Region: PP2C_SIG; smart00331
699034011662	exopolyphosphatase; Region: exo_poly_only; TIGR03706
699034011663	Ppx/GppA phosphatase family; Region: Ppx-GppA; pfam02541
699034011664	Septum formation initiator; Region: DivIC; cl17659
699034011665	Spore cortex protein YabQ (Spore_YabQ); Region: Spore_YabQ; pfam09578
699034011666	YabP family; Region: YabP; cl06766
699034011667	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
699034011668	RNA binding surface [nucleotide binding]; other site
699034011669	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
699034011670	IHF - DNA interface [nucleotide binding]; other site
699034011671	IHF dimer interface [polypeptide binding]; other site
699034011672	Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain [General function prediction only]; Region: COG3956
699034011673	N-terminal S-AdoMet dependent methylase domain of Bacillus subtilis YabN and related proteins; Region: YabN_N; cd11723
699034011674	putative SAM binding site [chemical binding]; other site
699034011675	putative homodimer interface [polypeptide binding]; other site
699034011676	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
699034011677	homodimer interface [polypeptide binding]; other site
699034011678	metal binding site [ion binding]; metal-binding site
699034011679	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) C-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs' Region: NTP-PPase_MazG_Cterm; cd11529
699034011680	homodimer interface [polypeptide binding]; other site
699034011681	active site
699034011682	putative chemical substrate binding site [chemical binding]; other site
699034011683	metal binding site [ion binding]; metal-binding site
699034011684	stage V sporulation protein B; Region: spore_V_B; TIGR02900
699034011685	Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins; Region: MATE_SpoVB_like; cd13124
699034011686	stage V sporulation protein T; Region: spore_V_T; TIGR02851
699034011687	looped-hinge helix DNA binding domain, AbrB family; Region: lp_hng_hel_AbrB; TIGR01439
699034011688	peptidylprolyl isomerase; Provisional; Region: prsA; PRK00059
699034011689	SurA N-terminal domain; Region: SurA_N_3; cl07813
699034011690	PPIC-type PPIASE domain; Region: Rotamase; pfam00639
699034011691	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
699034011692	Bifunctional transglycosylase second domain; Region: UB2H; pfam14814
699034011693	CarD-like/TRCF domain; Region: CarD_TRCF; smart01058
699034011694	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
699034011695	ATP binding site [chemical binding]; other site
699034011696	putative Mg++ binding site [ion binding]; other site
699034011697	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
699034011698	nucleotide binding region [chemical binding]; other site
699034011699	ATP-binding site [chemical binding]; other site
699034011700	This domain is found in proteins necessary for strand-specific repair in DNA such as TRCF in Escherichia coli; Region: TRCF; smart00982
699034011701	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
699034011702	putative active site [active]
699034011703	catalytic residue [active]
699034011704	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
699034011705	Type II secretory pathway, prepilin signal peptidase PulO and related peptidases [Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: PulO; COG1989
699034011706	Bacterial Peptidase A24 N-terminal domain; Region: DiS_P_DiS; pfam06750
699034011707	Type IV leader peptidase family; Region: Peptidase_A24; pfam01478
699034011708	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cl18944
699034011709	Pilus retraction ATPase PilT. PilT is a nucleotide binding protein responsible for the retraction of type IV pili, likely by pili disassembly. This retraction provides the force required for travel of bacteria in low water environments by a mechanism...; Region: PilT; cd01131
699034011710	Walker A motif; other site
699034011711	ATP binding site [chemical binding]; other site
699034011712	Walker B motif; other site
699034011713	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
699034011714	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
699034011715	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
699034011716	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
699034011717	Fimbrial assembly protein (PilN); Region: PilN; cl19830
699034011718	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
699034011719	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
699034011720	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
699034011721	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
699034011722	Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulE; COG2804
699034011723	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
699034011724	Walker A motif; other site
699034011725	ATP binding site [chemical binding]; other site
699034011726	Walker B motif; other site
699034011727	Type IV pilin N-term methylation site GFxxxE; Region: N_methyl_2; pfam13544
699034011728	type II secretion system protein G; Region: typeII_sec_gspG; TIGR01710
699034011729	ribose-phosphate pyrophosphokinase; Provisional; Region: PRK01259
699034011730	N-terminal domain of ribose phosphate pyrophosphokinase; Region: Pribosyltran_N; pfam13793
699034011731	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
699034011732	active site
699034011733	bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Provisional; Region: glmU; PRK14354
699034011734	N-terminal domain of bacterial GlmU; Region: GT2_GlmU_N_bac; cd02540
699034011735	Substrate binding site; other site
699034011736	Mg++ binding site; other site
699034011737	N-acetyl-glucosamine-1-phosphate uridyltransferase (GlmU), C-terminal left-handed beta-helix (LbH) acetyltransferase domain: GlmU is also known as UDP-N-acetylglucosamine pyrophosphorylase. It is a bifunctional bacterial enzyme that catalyzes two...; Region: LbH_GlmU_C; cd03353
699034011738	active site
699034011739	substrate binding site [chemical binding]; other site
699034011740	CoA binding site [chemical binding]; other site
699034011741	regulatory protein SpoVG; Reviewed; Region: PRK13259
699034011742	pur operon repressor; Provisional; Region: PRK09213
699034011743	Bacterial purine repressor, N-terminal; Region: PuR_N; pfam09182
699034011744	Phosphoribosyl transferase (PRT)-type I domain; Region: PRTases_typeI; cd06223
699034011745	active site
699034011746	UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: murC; PRK00421
699034011747	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
699034011748	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
699034011749	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
699034011750	Dynein, heavy chain [Cytoskeleton]; Region: DYN1; COG5245
699034011751	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
699034011752	cation diffusion facilitator family transporter; Region: CDF; TIGR01297
699034011753	M20 Peptidase T like enzymes specifically cleave tripeptides; Region: M20_peptT_like; cd05683
699034011754	peptidase T-like protein; Region: PepT-like; TIGR01883
699034011755	metal binding site [ion binding]; metal-binding site
699034011756	putative dimer interface [polypeptide binding]; other site
699034011757	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
699034011758	S-adenosylmethionine binding site [chemical binding]; other site
699034011759	ribonuclease M5; Region: 5S_RNA_mat_M5; TIGR00334
699034011760	TOPRIM_ RNase M5_like: The topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain found in Ribonuclease M5: (RNase M5) and other small primase-like proteins from bacteria and archaea.  RNase M5 catalyzes the maturation of 5S rRNA in low...; Region: TOPRIM_RNase_M5_like; cd01027
699034011761	putative active site [active]
699034011762	putative metal binding site [ion binding]; other site
699034011763	Domain of unknown function (DUF4093); Region: DUF4093; pfam13331
699034011764	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
699034011765	putative 2-aminoethylphosphonate ABC transporter, permease protein; Region: PhnU2; TIGR03262
699034011766	Bacterial extracellular solute-binding protein; Region: SBP_bac_1; cl17199
699034011767	ABC-type thiamine transport system, periplasmic component [Coenzyme metabolism]; Region: TbpA; COG4143
699034011768	putative 2-aminoethylphosphonate ABC transporter, permease protein; Region: PhnU2; TIGR03262
699034011769	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034011770	dimer interface [polypeptide binding]; other site
699034011771	conserved gate region; other site
699034011772	putative PBP binding loops; other site
699034011773	ABC-ATPase subunit interface; other site
699034011774	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
699034011775	dimer interface [polypeptide binding]; other site
699034011776	conserved gate region; other site
699034011777	putative PBP binding loops; other site
699034011778	ABC-ATPase subunit interface; other site
699034011779	putative 2-aminoethylphosphonate ABC transporter, ATP-binding protein; Region: PhnT2; TIGR03265
699034011780	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034011781	Walker A/P-loop; other site
699034011782	ATP binding site [chemical binding]; other site
699034011783	Q-loop/lid; other site
699034011784	ABC transporter signature motif; other site
699034011785	Walker B; other site
699034011786	D-loop; other site
699034011787	H-loop/switch region; other site
699034011788	TOBE domain; Region: TOBE_2; pfam08402
699034011789	Predicted metal-dependent phosphoesterases (PHP family) [General function prediction only]; Region: COG0613
699034011790	Polymerase and Histidinol Phosphatase domain of Histidinol phosphate phosphatase (HisPPase) AMP bound; Region: PHP_HisPPase_AMP; cd07438
699034011791	active site
699034011792	phosphonate metabolism protein PhnM; Provisional; Region: PRK15446
699034011793	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
699034011794	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
699034011795	active site
699034011796	phosphonate C-P lyase system protein PhnL; Region: CP_lyasePhnL; TIGR02324
699034011797	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034011798	Walker A/P-loop; other site
699034011799	ATP binding site [chemical binding]; other site
699034011800	Q-loop/lid; other site
699034011801	ABC transporter signature motif; other site
699034011802	Walker B; other site
699034011803	D-loop; other site
699034011804	H-loop/switch region; other site
699034011805	phosphonate C-P lyase system protein PhnK; Provisional; Region: phnK; PRK11701
699034011806	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
699034011807	Walker A/P-loop; other site
699034011808	ATP binding site [chemical binding]; other site
699034011809	Q-loop/lid; other site
699034011810	ABC transporter signature motif; other site
699034011811	Walker B; other site
699034011812	D-loop; other site
699034011813	H-loop/switch region; other site
699034011814	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
699034011815	Phosphonate metabolizm protein PhnJ; Region: PhnJ; pfam06007
699034011816	Bacterial phosphonate metabolizm protein (PhnI); Region: PhnI; pfam05861
699034011817	phosphonate C-P lyase system protein PhnH; Region: PhnH_redo; TIGR03292
699034011818	phosphonate C-P lyase system protein PhnG; Region: PhnG_redo; TIGR03293
699034011819	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
699034011820	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
699034011821	active site
699034011822	methionyl-tRNA synthetase; Reviewed; Region: PRK12267
699034011823	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
699034011824	active site
699034011825	HIGH motif; other site
699034011826	KMSKS motif; other site
699034011827	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
699034011828	tRNA binding surface [nucleotide binding]; other site
699034011829	anticodon binding site; other site
699034011830	tRNA-binding-domain-containing Escherichia coli methionyl-tRNA synthetase (EcMetRS)-like proteins.  This family includes EcMetRS and Aquifex aeolicus Trbp111 (AaTrbp111). This domain has general tRNA binding properties.  MetRS aminoacylates methionine...; Region: tRNA_bind_EcMetRS_like; cd02800
699034011831	dimer interface [polypeptide binding]; other site
699034011832	putative tRNA-binding site [nucleotide binding]; other site
699034011833	Uncharacterized membrane protein [Function unknown]; Region: SpmB; cl17667
699034011834	Uncharacterized membrane protein, required for spore maturation in B.subtilis. [General function prediction only]; Region: SpmA; COG2715
699034011835	nicotinate phosphoribosyltransferase; Validated; Region: PRK09243
699034011836	Nicotinate phosphoribosyltransferase (NAPRTase), subgroup A. Nicotinate phosphoribosyltransferase catalyses the formation of NAMN and PPi from 5-phosphoribosy -1-pyrophosphate (PRPP) and nicotinic acid, this is the first, and also rate limiting, reaction...; Region: NAPRTase_A; cd01570
699034011837	active site
699034011838	Transcriptional regulators [Transcription]; Region: Lrp; COG1522
699034011839	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
699034011840	putative DNA binding site [nucleotide binding]; other site
699034011841	putative Zn2+ binding site [ion binding]; other site
699034011842	AsnC family; Region: AsnC_trans_reg; pfam01037
699034011843	HD domain; Region: HD; pfam01966
699034011844	Ribosomal RNA small subunit methyltransferase I, also known as rRNA (cytidine-2'-O-)-methyltransferase RsmI; Region: RsmI; cd11648
699034011845	putative SAM binding site [chemical binding]; other site
699034011846	putative homodimer interface [polypeptide binding]; other site
699034011847	Predicted O-methyltransferase [General function prediction only]; Region: COG4123
699034011848	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
699034011849	S-adenosylmethionine binding site [chemical binding]; other site
699034011850	Uncharacterized homolog of PSP1 [Function unknown]; Region: COG1774
699034011851	DNA polymerase III subunit delta'; Validated; Region: PRK05564
699034011852	DNA polymerase III subunit delta'; Validated; Region: PRK08485
699034011853	Thymidylate kinase [Nucleotide transport and metabolism]; Region: Tmk; COG0125
699034011854	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
699034011855	TMP-binding site; other site
699034011856	ATP-binding site [chemical binding]; other site
699034011857	Arginine/lysine/ornithine decarboxylases [Amino acid transport and metabolism]; Region: LdcC; COG1982
699034011858	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl18945
699034011859	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
699034011860	catalytic residue [active]
699034011861	Orn/Lys/Arg decarboxylase, C-terminal domain; Region: OKR_DC_1_C; pfam03711
699034011862	Domain of unknown function (DUF378); Region: DUF378; pfam04070
699034011863	potential RNA of insufficient length (23S ribosomal RNA)
699034011864	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
699034011865	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
699034011866	dimer interface [polypeptide binding]; other site
699034011867	putative anticodon binding site; other site
699034011868	Lys_tRNA synthetase (LysRS) class II core domain. Class II LysRS is a dimer which attaches a lysine to the 3' OH group of ribose of the appropriate tRNA. Its assignment to class II aaRS is based upon its structure and the presence of three...; Region: LysRS_core; cd00775
699034011869	motif 1; other site
699034011870	active site
699034011871	motif 2; other site
699034011872	motif 3; other site
699034011873	transcription elongation factor GreA; Reviewed; Region: greA; PRK00226
699034011874	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
699034011875	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
699034011876	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
699034011877	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
699034011878	FMN binding site [chemical binding]; other site
699034011879	active site
699034011880	catalytic residues [active]
699034011881	substrate binding site [chemical binding]; other site
699034011882	pantothenate kinase; Reviewed; Region: PRK13318
699034011883	Predicted membrane protein [Function unknown]; Region: COG4684
699034011884	Protein of unknown function (DUF3816); Region: DUF3816; pfam12822
699034011885	nylC-like family; composed of proteins with similarity to Flavobacterium endo-type 6-aminohexanoate-oligomer hydrolase (EIII), the product of the nylon oligomer degradation gene, nylC. EIII is an amide hydrolase that catalyzes the degradation of...; Region: nylC_like; cd02252
699034011886	putative active site pocket [active]
699034011887	cleavage site
699034011888	Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to...; Region: HTH_ARSR; cd00090
699034011889	bifunctional biotin--[acetyl-CoA-carboxylase] synthetase/biotin operon repressor; Provisional; Region: PRK11886
699034011890	putative Zn2+ binding site [ion binding]; other site
699034011891	putative DNA binding site [nucleotide binding]; other site
699034011892	Biotin/lipoate A/B protein ligase family; Region: BPL_LplA_LipB; pfam03099
699034011893	FtsH Extracellular; Region: FtsH_ext; pfam06480
699034011894	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
699034011895	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034011896	Walker A motif; other site
699034011897	ATP binding site [chemical binding]; other site
699034011898	Walker B motif; other site
699034011899	arginine finger; other site
699034011900	Peptidase family M41; Region: Peptidase_M41; pfam01434
699034011901	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
699034011902	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
699034011903	Ligand Binding Site [chemical binding]; other site
699034011904	TilS substrate C-terminal domain; Region: TilS_C; smart00977
699034011905	Domain of unknown function (DUF1934); Region: DUF1934; pfam09148
699034011906	glutamate racemase; Provisional; Region: PRK00865
699034011907	Cell Wall Hydrolase; Region: Hydrolase_2; pfam07486
699034011908	Stage II sporulation protein R (spore_II_R); Region: Spore_II_R; pfam09551
699034011909	Transcriptional regulators [Transcription]; Region: GntR; COG1802
699034011910	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
699034011911	DNA-binding site [nucleotide binding]; DNA binding site
699034011912	FCD domain; Region: FCD; pfam07729
699034011913	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: ipk; PRK00128
699034011914	GHMP kinases N terminal domain; Region: GHMP_kinases_N; pfam00288
699034011915	GHMP kinases C terminal; Region: GHMP_kinases_C; pfam08544
699034011916	Domain of unknown function (DUF3794); Region: DUF3794; pfam12673
699034011917	Domain of unknown function (DUF3794); Region: DUF3794; pfam12673
699034011918	Domain of unknown function (DUF3794); Region: DUF3794; pfam12673
699034011919	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
699034011920	Protein of unknown function (DUF1021); Region: DUF1021; pfam06257
699034011921	YabG peptidase U57; Region: Peptidase_U57; pfam05582
699034011922	renal dipeptidase (rDP), best studied in mammals and also called membrane or microsomal dipeptidase, is a membrane-bound glycoprotein hydrolyzing dipeptides and is involved in hydrolytic metabolism of penem and carbapenem beta-lactam antibiotics; Region: rDP_like; cd01301
699034011923	active site
699034011924	dimer interface [polypeptide binding]; other site
699034011925	hypothetical protein; Provisional; Region: PRK05590
699034011926	UPF0489 domain; Region: UPF0489; pfam12640
699034011927	Solute carrier 5 family, sodium/glucose transporters and related proteins; solute-binding domain; Region: SLC5sbd; cd10322
699034011928	Na binding site [ion binding]; other site
699034011929	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
699034011930	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
699034011931	putative substrate translocation pore; other site
699034011932	CGS_like: Cystathionine gamma-synthase is a PLP dependent enzyme and catalyzes the committed step of methionine biosynthesis. This pathway is unique to microorganisms and plants, rendering the enzyme an attractive target for the development of...; Region: CGS_like; cd00614
699034011933	homodimer interface [polypeptide binding]; other site
699034011934	substrate-cofactor binding pocket; other site
699034011935	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034011936	catalytic residue [active]
699034011937	Site-specific recombinases, DNA invertase Pin homologs [DNA replication, recombination, and repair]; Region: PinR; COG1961
699034011938	Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and...; Region: SR_ResInv; cd03768
699034011939	catalytic residues [active]
699034011940	catalytic nucleophile [active]
699034011941	Presynaptic Site I dimer interface [polypeptide binding]; other site
699034011942	Synaptic Antiparallel dimer interface [polypeptide binding]; other site
699034011943	Synaptic Flat tetramer interface [polypeptide binding]; other site
699034011944	Synaptic Site I dimer interface [polypeptide binding]; other site
699034011945	DNA binding site [nucleotide binding]
699034011946	Domain of unknown function (DUF1413); Region: DUF1413; pfam07205
699034011947	Domain of unknown function (DUF4163); Region: DUF4163; pfam13739
699034011948	Protein of unknown function (DUF3298); Region: DUF3298; pfam11738
699034011949	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
699034011950	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
699034011951	S-adenosylmethionine binding site [chemical binding]; other site
699034011952	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
699034011953	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
699034011954	active site
699034011955	Helix-Turn-Helix DNA binding domain of the BmrR transcription regulator; Region: HTH_BmrR; cd01107
699034011956	DNA binding residues [nucleotide binding]
699034011957	Cd(II)/Pb(II)-responsive transcriptional regulator; Region: CadR-PbrR; TIGR02047
699034011958	drug binding residues [chemical binding]; other site
699034011959	dimer interface [polypeptide binding]; other site
699034011960	GyrI-like small molecule binding domain; Region: GyrI-like; cl01368
699034011961	MacB-like periplasmic core domain; Region: MacB_PCD; pfam12704
699034011962	FtsX-like permease family; Region: FtsX; pfam02687
699034011963	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
699034011964	FtsX-like permease family; Region: FtsX; pfam02687
699034011965	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
699034011966	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
699034011967	Walker A/P-loop; other site
699034011968	ATP binding site [chemical binding]; other site
699034011969	Q-loop/lid; other site
699034011970	ABC transporter signature motif; other site
699034011971	Walker B; other site
699034011972	D-loop; other site
699034011973	H-loop/switch region; other site
699034011974	Signal transduction histidine kinase [Signal transduction mechanisms]; Region: BaeS; COG0642
699034011975	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034011976	dimer interface [polypeptide binding]; other site
699034011977	phosphorylation site [posttranslational modification]
699034011978	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034011979	ATP binding site [chemical binding]; other site
699034011980	Mg2+ binding site [ion binding]; other site
699034011981	G-X-G motif; other site
699034011982	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034011983	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034011984	active site
699034011985	phosphorylation site [posttranslational modification]
699034011986	intermolecular recognition site; other site
699034011987	dimerization interface [polypeptide binding]; other site
699034011988	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034011989	DNA binding site [nucleotide binding]
699034011990	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
699034011991	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
699034011992	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
699034011993	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
699034011994	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
699034011995	ATP-grasp domain; Region: ATP-grasp_4; cl17255
699034011996	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
699034011997	IMP binding site; other site
699034011998	dimer interface [polypeptide binding]; other site
699034011999	interdomain contacts; other site
699034012000	partial ornithine binding site; other site
699034012001	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
699034012002	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988
699034012003	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
699034012004	catalytic site [active]
699034012005	subunit interface [polypeptide binding]; other site
699034012006	carbamoyl phosphate synthase large subunit; Reviewed; Region: carB; PRK05294
699034012007	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
699034012008	Carbamoyl-phosphate synthase L chain, ATP binding domain; Region: CPSase_L_D2; pfam02786
699034012009	Carbamoyl-phosphate synthetase large chain, oligomerisation domain; Region: CPSase_L_D3; pfam02787
699034012010	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
699034012011	ATP-grasp domain; Region: ATP-grasp_4; cl17255
699034012012	Methylglyoxal synthase-like domain from type II glutamine-dependent carbamoyl phosphate synthetase (CSP). CSP, a CarA and CarB heterodimer, catalyzes the production of carbamoyl phosphate which is subsequently employed in the metabolic pathways...; Region: MGS_CPS_II; cd01424
699034012013	IMP binding site; other site
699034012014	dimer interface [polypeptide binding]; other site
699034012015	interdomain contacts; other site
699034012016	partial ornithine binding site; other site
699034012017	carbamoyl phosphate synthase small subunit; Reviewed; Region: PRK12564
699034012018	Carbamoyl-phosphate synthase small chain, CPSase domain; Region: CPSase_sm_chain; pfam00988
699034012019	Small chain of the glutamine-dependent form of carbamoyl phosphate synthase, CPSase II; Region: GATase1_CPSase; cd01744
699034012020	catalytic site [active]
699034012021	subunit interface [polypeptide binding]; other site
699034012022	Orotidine 5'-phosphate decarboxylase (ODCase) is a dimeric enzyme that decarboxylates orotidine 5'-monophosphate (OMP) to form uridine 5'-phosphate (UMP), an essential step in the pyrimidine biosynthetic pathway. In mammals, UMP synthase...; Region: OMP_decarboxylase_like; cd04725
699034012023	active site
699034012024	dimer interface [polypeptide binding]; other site
699034012025	Protein of unknown function (DUF1847); Region: DUF1847; pfam08901
699034012026	Nitroreductase family; Region: Nitroreductase; pfam00881
699034012027	FMN binding site [chemical binding]; other site
699034012028	dimer interface [polypeptide binding]; other site
699034012029	Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer,  utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are...; Region: Nitro_FMN_reductase; cl00514
699034012030	Thermophilic metalloprotease (M29); Region: Peptidase_M29; pfam02073
699034012031	Homocysteine S-methyltransferase; Region: S-methyl_trans; cl14105
699034012032	Pterin binding enzymes. This family includes dihydropteroate synthase (DHPS) and cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH).  DHPS, a...; Region: Pterin_binding; cl00219
699034012033	substrate binding pocket [chemical binding]; other site
699034012034	dimer interface [polypeptide binding]; other site
699034012035	inhibitor binding site; inhibition site
699034012036	B12 binding domain of corrinoid proteins. A family of small methanogenic corrinoid proteins that bind methyl-Co(III) 5-hydroxybenzimidazolylcobamide as a cofactor. They play a role on the methanogenesis from trimethylamine, dimethylamine or...; Region: corrinoid_protein_B12-BD; cd02070
699034012037	B12 binding site [chemical binding]; other site
699034012038	cobalt ligand [ion binding]; other site
699034012039	Vitamin B12 dependent methionine synthase, activation domain; Region: Met_synt_B12; pfam02965
699034012040	S-ribosylhomocysteinase; Provisional; Region: PRK02260
699034012041	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
699034012042	dimer interface [polypeptide binding]; other site
699034012043	phosphorylation site [posttranslational modification]
699034012044	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
699034012045	ATP binding site [chemical binding]; other site
699034012046	Mg2+ binding site [ion binding]; other site
699034012047	G-X-G motif; other site
699034012048	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
699034012049	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
699034012050	active site
699034012051	phosphorylation site [posttranslational modification]
699034012052	intermolecular recognition site; other site
699034012053	dimerization interface [polypeptide binding]; other site
699034012054	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
699034012055	DNA binding site [nucleotide binding]
699034012056	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: VanY; COG1876
699034012057	D-alanyl-D-alanine carboxypeptidase; Region: VanY; pfam02557
699034012058	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
699034012059	Ligand Binding Site [chemical binding]; other site
699034012060	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
699034012061	Predicted phosphohydrolases [General function prediction only]; Region: Icc; COG1409
699034012062	putative active site [active]
699034012063	putative metal binding site [ion binding]; other site
699034012064	Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism]; Region: WcaG; COG0451
699034012065	atypical (a) SDRs, subgroup 1; Region: SDR_a1; cd05265
699034012066	putative NAD(P) binding site [chemical binding]; other site
699034012067	active site
699034012068	Predicted phosphatases [General function prediction only]; Region: Gph; COG0546
699034012069	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
699034012070	active site
699034012071	motif I; other site
699034012072	motif II; other site
699034012073	Ferredoxin [Energy production and conversion]; Region: NapF; COG1145
699034012074	4Fe-4S single cluster domain; Region: Fer4_13; pfam13370
699034012075	dihydroorotase; Provisional; Region: PRK09237
699034012076	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
699034012077	active site
699034012078	Uncharacterized protein family (UPF0051); Region: UPF0051; pfam01458
699034012079	Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones]; Region: sufC; COG0396
699034012080	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034012081	Walker A/P-loop; other site
699034012082	ATP binding site [chemical binding]; other site
699034012083	Q-loop/lid; other site
699034012084	ABC transporter signature motif; other site
699034012085	Walker B; other site
699034012086	D-loop; other site
699034012087	H-loop/switch region; other site
699034012088	Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily; Region: Glyoxalase; pfam00903
699034012089	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_16; cd07263
699034012090	Subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins similar to Thermotoga marina NorM; Region: MATE_NorM_like; cd13137
699034012091	MATE family multidrug exporter; Provisional; Region: PRK10189
699034012092	Staygreen protein; Region: Staygreen; pfam12638
699034012093	Protein of unknown function, DUF488; Region: DUF488; pfam04343
699034012094	Cna protein B-type domain; Region: Cna_B; pfam05738
699034012095	Cna protein B-type domain; Region: Cna_B; pfam05738
699034012096	Bacterial protein of unknown function (DUF961); Region: DUF961; pfam06125
699034012097	Bacterial protein of unknown function (DUF961); Region: DUF961; pfam06125
699034012098	Protein of unknown function (DUF3788); Region: DUF3788; pfam12663
699034012099	This conserved domain belongs to a superfamily including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases; Region: Glo_EDI_BRP_like_23; cd09011
699034012100	Protein of unknown function (DUF3795); Region: DUF3795; pfam12675
699034012101	Tripartite tricarboxylate transporter TctA family; Region: TctA; cl00772
699034012102	YcxB-like protein; Region: YcxB; pfam14317
699034012103	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034012104	Walker A motif; other site
699034012105	ATP binding site [chemical binding]; other site
699034012106	Walker B motif; other site
699034012107	arginine finger; other site
699034012108	Replication initiation factor; Region: Rep_trans; pfam02486
699034012109	Protein of unknown function (DUF3789); Region: DUF3789; pfam12664
699034012110	Chloramphenicol acetyltransferase; Region: CAT; cl02008
699034012111	Antirestriction protein (ArdA); Region: ArdA; cl01953
699034012112	Antirestriction protein (ArdA); Region: ArdA; pfam07275
699034012113	TcpE family; Region: TcpE; pfam12648
699034012114	AAA-like domain; Region: AAA_10; pfam12846
699034012115	Fusaric acid resistance protein-like; Region: FUSC_2; pfam13515
699034012116	Histone H1-like nucleoprotein HC2; Region: HC2; cl19298
699034012117	Lysozyme-like; Region: Lysozyme_like; pfam13702
699034012118	NlpC/P60 family; Region: NLPC_P60; pfam00877
699034012119	Conjugative transposon protein TcpC; Region: TpcC; pfam12642
699034012120	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
699034012121	Prolyl oligopeptidase family; Region: Peptidase_S9; cl19144
699034012122	Transcriptional regulator [Transcription]; Region: AcrR; COG1309
699034012123	Bacterial regulatory proteins, tetR family; Region: TetR_N; pfam00440
699034012124	ABC-type multidrug transport system, ATPase component [Defense mechanisms]; Region: CcmA; COG1131
699034012125	ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; Region: ABC_DR_subfamily_A; cd03230
699034012126	Walker A/P-loop; other site
699034012127	ATP binding site [chemical binding]; other site
699034012128	Q-loop/lid; other site
699034012129	ABC transporter signature motif; other site
699034012130	Walker B; other site
699034012131	D-loop; other site
699034012132	H-loop/switch region; other site
699034012133	ABC-2 family transporter protein; Region: ABC2_membrane_3; pfam12698
699034012134	FlhB HrpN YscU SpaS Family; Region: Bac_export_2; cl19167
699034012135	Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism]; Region: MMT1; COG0053
699034012136	RNA polymerase sigma factor, sigma-70 family; Region: sigma70-ECF; TIGR02937
699034012137	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cl17257
699034012138	DNA binding domain of tn916 integrase; Region: Integrase_DNA; pfam02920
699034012139	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
699034012140	active site
699034012141	DNA binding site [nucleotide binding]
699034012142	Int/Topo IB signature motif; other site
699034012143	Helix-Turn-Helix DNA binding domain of the BmrR transcription regulator; Region: HTH_BmrR; cd01107
699034012144	Predicted transcriptional regulators [Transcription]; Region: SoxR; COG0789
699034012145	DNA binding residues [nucleotide binding]
699034012146	drug binding residues [chemical binding]; other site
699034012147	dimer interface [polypeptide binding]; other site
699034012148	Bacterial transcription activator, effector binding domain; Region: AraC_E_bind; smart00871
699034012149	potassium/proton antiporter; Reviewed; Region: PRK05326
699034012150	Transmembrane subunit (TM) of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which are involved in the uptake of branched-chain amino acids (AAs), as well as TMs of transporters involved in the uptake of...; Region: TM_PBP1_branched-chain-AA_like; cl00454
699034012151	TrkA-C domain; Region: TrkA_C; pfam02080
699034012152	Transposase and inactivated derivatives [DNA replication, recombination, and repair]; Region: COG0675
699034012153	Helix-turn-helix domain; Region: HTH_OrfB_IS605; pfam12323
699034012154	Probable transposase; Region: OrfB_IS605; pfam01385
699034012155	Putative transposase DNA-binding domain; Region: OrfB_Zn_ribbon; pfam07282
699034012156	Transposase IS200 like; Region: Y1_Tnp; cl00848
699034012157	potassium/proton antiporter; Reviewed; Region: PRK05326
699034012158	Predicted Zn-dependent protease (DUF2268); Region: DUF2268; pfam10026
699034012159	Escherichia coli PhnB and similar proteins; the E. coli phnB gene is found next to an operon involved in the cleavage of carbon-phosphorus bonds in unactivated alkylphosphonates; Region: PhnB_like; cd06588
699034012160	dimer interface [polypeptide binding]; other site
699034012161	Acetyltransferase (GNAT) domain; Region: Acetyltransf_10; pfam13673
699034012162	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
699034012163	Coenzyme A binding pocket [chemical binding]; other site
699034012164	YmaF family; Region: YmaF; pfam12788
699034012165	Pentapeptide repeats containing protein [Function unknown]; Region: COG1357
699034012166	Pentapeptide repeats (8 copies); Region: Pentapeptide; pfam00805
699034012167	Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism]; Region: PhnA; COG2824
699034012168	PhnA Zinc-Ribbon; Region: PhnA_Zn_Ribbon; pfam08274
699034012169	PhnA protein; Region: PhnA; pfam03831
699034012170	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
699034012171	putative bacteriocin export ABC transporter, lactococcin 972 group; Region: L_ocin_972_ABC; TIGR03608
699034012172	Walker A/P-loop; other site
699034012173	ATP binding site [chemical binding]; other site
699034012174	Q-loop/lid; other site
699034012175	ABC transporter signature motif; other site
699034012176	Walker B; other site
699034012177	D-loop; other site
699034012178	H-loop/switch region; other site
699034012179	bacteriocin-associated integral membrane (putative immunity) protein; Region: bact_immun_7tm; TIGR01654
699034012180	Protein of unknown function (DUF1430); Region: DUF1430; pfam07242
699034012181	Entner-Doudoroff aldolase; Region: eda; TIGR01182
699034012182	KDPG and KHG aldolase; Region: KDPG_aldolase; cd00452
699034012183	active site
699034012184	intersubunit interface [polypeptide binding]; other site
699034012185	catalytic residue [active]
699034012186	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
699034012187	inhibitor site; inhibition site
699034012188	active site
699034012189	dimer interface [polypeptide binding]; other site
699034012190	catalytic residue [active]
699034012191	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
699034012192	putative active site [active]
699034012193	PTS system ascorbate-specific transporter subunit IIC; Reviewed; Region: PRK12997
699034012194	PTS_IIB_ascorbate: subunit IIB of enzyme II (EII) of the L-ascorbate-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In this system, EII is an L-ascorbate-specific permease with two cytoplasmic subunits (IIA and IIB) and a...; Region: PTS_IIB_ascorbate; cd05563
699034012195	active site
699034012196	P-loop; other site
699034012197	phosphorylation site [posttranslational modification]
699034012198	Transcriptional antiterminator [Transcription]; Region: BglG; COG3711
699034012199	Mga helix-turn-helix domain; Region: Mga; pfam05043
699034012200	PRD domain; Region: PRD; pfam00874
699034012201	PTS_IIB_bgl_like: the PTS (phosphotransferase system) IIB domain of a family of sensory systems composed of a membrane-bound sugar-sensor (similar to BglF) and a transcription antiterminator (similar to BglG) which regulate expression of genes involved...; Region: PTS_IIB_bgl_like; cd05568
699034012202	active site
699034012203	P-loop; other site
699034012204	phosphorylation site [posttranslational modification]
699034012205	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
699034012206	active site
699034012207	phosphorylation site [posttranslational modification]
699034012208	Protein of unknown function (DUF1097); Region: DUF1097; pfam06496
699034012209	Multimeric flavodoxin WrbA [General function prediction only]; Region: WrbA; COG0655
699034012210	Uncharacterized conserved protein [Function unknown]; Region: COG5276
699034012211	Transcriptional regulator [Transcription]; Region: LysR; COG0583
699034012212	Bacterial regulatory helix-turn-helix protein, lysR family; Region: HTH_1; pfam00126
699034012213	The substrate binding domain of LysR-type transcriptional regulators (LTTRs), a member of the type 2 periplasmic binding fold protein superfamily; Region: PBP2_LTTR_substrate; cd05466
699034012214	dimerization interface [polypeptide binding]; other site
699034012215	2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the...; Region: KdgK; cd01166
699034012216	substrate binding site [chemical binding]; other site
699034012217	ATP binding site [chemical binding]; other site
699034012218	conserved hypothetical protein EF_0839/AHA_3917; Region: EF_0839; TIGR03581
699034012219	uncharacterized pyridoxal phosphate-dependent enzyme; Region: selA_rel; TIGR01437
699034012220	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
699034012221	catalytic residue [active]
699034012222	probable amidohydrolase EF_0837/AHA_3915; Region: EF_0837; TIGR03583
699034012223	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
699034012224	active site
699034012225	Bacterial protein of unknown function (DUF871); Region: DUF871; pfam05913
699034012226	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
699034012227	Transcriptional regulators [Transcription]; Region: PhnF; COG2188
699034012228	Winged helix-turn-helix (WHTH) DNA-binding domain of the GntR family of transcriptional regulators; Region: WHTH_GntR; cd07377
699034012229	DNA-binding site [nucleotide binding]; DNA binding site
699034012230	UTRA domain; Region: UTRA; cl17743
699034012231	PTS_IIA, PTS system, lactose/cellobiose specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_lac; cd00215
699034012232	active site
699034012233	methionine cluster; other site
699034012234	phosphorylation site [posttranslational modification]
699034012235	metal binding site [ion binding]; metal-binding site
699034012236	PTS_IIB_chitobiose_lichenan: subunit IIB of enzyme II (EII) of the N,N-diacetylchitobiose-specific and lichenan-specific phosphoenolpyruvate:carbohydrate phosphotransferase system (PTS). In these systems, EII is either a lichenan- or an N; Region: PTS_IIB_chitobiose_lichenan; cd05564
699034012237	active site
699034012238	P-loop; other site
699034012239	phosphorylation site [posttranslational modification]
699034012240	rRNA large subunit methyltransferase; Provisional; Region: PRK00103
699034012241	Phosphotransferase system cellobiose-specific component IIC [Carbohydrate transport and metabolism]; Region: CelB; COG1455
699034012242	EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2).  The EAL domain has been shown to stimulate degradation of a second...; Region: EAL; cd01948
699034012243	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
699034012244	Peptidase M1 family containing bacterial Aminopeptidase N; Region: M1_APN_5; cd09604
699034012245	Zn binding site [ion binding]; other site
699034012246	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
699034012247	Replication initiation and membrane attachment; Region: DnaB_2; pfam07261
699034012248	DNA replication protein DnaC; Validated; Region: PRK06835
699034012249	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
699034012250	Walker A motif; other site
699034012251	ATP binding site [chemical binding]; other site
699034012252	Walker B motif; other site
699034012253	arginine finger; other site
699034012254	Adenylosuccinate synthetase (AdSS) catalyzes the first step in the de novo biosynthesis of AMP. IMP and L-aspartate are conjugated in a two-step reaction accompanied by the hydrolysis of GTP to GDP in the presence of Mg2+. In the first step, the...; Region: AdSS; cd03108
699034012255	GDP-binding site [chemical binding]; other site
699034012256	ACT binding site; other site
699034012257	IMP binding site; other site
699034012258	replicative DNA helicase; Region: DnaB; TIGR00665
699034012259	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
699034012260	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
699034012261	Walker A motif; other site
699034012262	ATP binding site [chemical binding]; other site
699034012263	Walker B motif; other site
699034012264	DNA binding loops [nucleotide binding]
699034012265	50S ribosomal protein L9; Reviewed; Region: rplI; PRK00137
699034012266	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
699034012267	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
699034012268	Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain [Signal transduction mechanisms]; Region: COG3887
699034012269	DHH family; Region: DHH; pfam01368
699034012270	DHHA1 domain; Region: DHHA1; pfam02272
699034012271	Predicted membrane protein (DUF2232); Region: DUF2232; pfam09991
699034012272	MazG-like family; Region: MazG-like; pfam12643
699034012273	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
699034012274	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
699034012275	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
699034012276	dimer interface [polypeptide binding]; other site
699034012277	ssDNA binding site [nucleotide binding]; other site
699034012278	tetramer (dimer of dimers) interface [polypeptide binding]; other site
699034012279	30S ribosomal protein S6; Reviewed; Region: rpsF; PRK00453
699034012280	Aspartate/tyrosine/aromatic aminotransferase [Amino acid transport and metabolism]; Region: COG0436
699034012281	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
699034012282	pyridoxal 5'-phosphate binding site [chemical binding]; other site
699034012283	homodimer interface [polypeptide binding]; other site
699034012284	catalytic residue [active]
699034012285	Bacterial protein of unknown function (DUF951); Region: DUF951; pfam06107
699034012286	Protein of unknown function (DUF3343); Region: DUF3343; pfam11823
699034012287	SirA_like_N, a protein of unknown function with an N-terminal SirA-like domain.  The SirA, YedF, YeeD protein family is present in bacteria as well as archaea. SirA (also known as UvrY,  and YhhP) belongs to a family of a two-component response...; Region: SirA_like_N; cd03421
699034012288	selenium metabolism protein YedF; Region: selenium_YedF; TIGR03527
699034012289	CPxP  motif; other site
699034012290	Predicted transcriptional regulators [Transcription]; Region: HipB; COG1396
699034012291	Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators; Region: HTH_XRE; cd00093
699034012292	non-specific DNA binding site [nucleotide binding]; other site
699034012293	salt bridge; other site
699034012294	sequence-specific DNA binding site [nucleotide binding]; other site
699034012295	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
699034012296	binding surface
699034012297	TPR motif; other site
699034012298	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
699034012299	binding surface
699034012300	TPR motif; other site
699034012301	Tetratricopeptide repeat; Region: TPR_12; pfam13424
699034012302	Tetratricopeptide repeat; Region: TPR_12; pfam13424
699034012303	Tetratricopeptide repeat; Region: TPR_12; pfam13424
699034012304	Sporulation and spore germination; Region: Germane; pfam10646
699034012305	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
699034012306	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
699034012307	catalytic residue [active]
699034012308	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
699034012309	ParB-like nuclease domain; Region: ParBc; pfam02195
699034012310	KorB domain; Region: KorB; pfam08535
699034012311	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
699034012312	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
699034012313	ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the...; Region: ParA; cd02042
699034012314	P-loop; other site
699034012315	Magnesium ion binding site [ion binding]; other site
699034012316	nucleoid occlusion protein; Region: nucleoid_noc; TIGR04285
699034012317	ParB-like nuclease domain; Region: ParB; smart00470
699034012318	Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane]; Region: GidB; COG0357
699034012319	Methyltransferase domain; Region: Methyltransf_31; pfam13847
699034012320	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
699034012321	S-adenosylmethionine binding site [chemical binding]; other site
699034012322	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
699034012323	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
699034012324	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
699034012325	tRNA modification GTPase TrmE; Reviewed; Region: trmE; PRK05291
699034012326	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
699034012327	Protein of unknown function (DUF677); Region: DUF677; pfam05055
699034012328	trmE is a tRNA modification GTPase; Region: trmE; cd04164
699034012329	G1 box; other site
699034012330	GTP/Mg2+ binding site [chemical binding]; other site
699034012331	Switch I region; other site
699034012332	G2 box; other site
699034012333	Switch II region; other site
699034012334	G3 box; other site
699034012335	G4 box; other site
699034012336	G5 box; other site
699034012337	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
699034012338	Jag N-terminus; Region: Jag_N; pfam14804
699034012339	Predicted RNA-binding protein [General function prediction only]; Region: Jag; COG1847
699034012340	jag_K homology RNA-binding domain. The KH domain is found in proteins homologous to the Bacillus subtilis protein Jag, which is associated with SpoIIIJ and is necessary for the third stage of sporulation.  The KH motif is a beta-alpha-alpha-beta-beta...; Region: jag_KH; cd02414
699034012341	G-X-X-G motif; other site
699034012342	R3H domain found in proteins homologous to Bacillus subtilus Jag, which is associated with SpoIIIJ. SpoIIIJ is necessary for the third stage of sporulation. The name of the R3H domain comes from the characteristic spacing of the most conserved arginine...; Region: R3H_jag; cd02644
699034012343	RxxxH motif; other site
699034012344	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
699034012345	Haemolytic domain; Region: Haemolytic; pfam01809
699034012346	ribonuclease P; Reviewed; Region: rnpA; PRK00499
699034012347	50S ribosomal protein L34; Reviewed; Region: rpmH; PRK00399