-- dump date   	20140619_032918
-- class       	Genbank::misc_feature
-- table       	misc_feature_note
-- id	note
707186000001	Uncharacterized conserved protein [Function unknown]; Region: COG2155
707186000002	Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit [Translation, ribosomal structure and biogenesis]; Region: GatC; COG0721
707186000003	Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis]; Region: GatA; COG0154
707186000004	aspartyl/glutamyl-tRNA amidotransferase subunit A; Reviewed; Region: gatA; PRK00012
707186000005	Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) [Translation, ribosomal structure and biogenesis]; Region: GatB; COG0064
707186000006	GatB/GatE catalytic domain; Region: GatB_N; pfam02934
707186000007	GatB domain; Region: GatB_Yqey; pfam02637
707186000008	Domain of unknown function (DUF3378); Region: DUF3378; pfam11858
707186000009	ribonuclease HIII; Region: rnhC; TIGR00716
707186000010	bacterial Ribonuclease HIII-like; Region: RNase_HII_bacteria_HIII_like; cd06590
707186000011	RNA/DNA hybrid binding site [nucleotide binding]; other site
707186000012	active site
707186000013	Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown]; Region: COG1426
707186000014	Helix-turn-helix domain; Region: HTH_25; pfam13413
707186000015	lipid A biosynthesis lauroyl acyltransferase; Provisional; Region: PRK05906
707186000016	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: LABLAT-like; Region: LPLAT_LABLAT-like; cd07984
707186000017	putative acyl-acceptor binding pocket; other site
707186000018	Uncharacterized conserved protein [Function unknown]; Region: COG1624
707186000019	DisA bacterial checkpoint controller nucleotide-binding; Region: DisA_N; pfam02457
707186000020	Bacterial Cytochrome Ubiquinol Oxidase; Region: Bac_Ubq_Cox; pfam01654
707186000021	Cytochrome bd-type quinol oxidase, subunit 2 [Energy production and conversion]; Region: AppB; COG1294
707186000022	cytochrome d ubiquinol oxidase subunit 2; Provisional; Region: PRK15003; cl12219
707186000023	NYN ribonuclease and ATPase of PhoH family domains [General    function prediction only]; Region: COG1875
707186000024	PIN (PilT N terminus) domain: Superfamily; Region: PIN_SF; cl14812
707186000025	putative active site [active]
707186000026	PhoH-like protein; Region: PhoH; pfam02562
707186000027	Bacterial SH3 domain homologues; Region: SH3b; smart00287
707186000028	Bacterial SH3 domain homologues; Region: SH3b; smart00287
707186000029	isoleucyl-tRNA synthetase; Reviewed; Region: ileS; PRK06039
707186000030	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
707186000031	HIGH motif; other site
707186000032	catalytic core domain of isoleucyl-tRNA synthetases; Region: IleRS_core; cd00818
707186000033	active site
707186000034	KMSKS motif; other site
707186000035	Anticodon-binding domain of archaeal, bacterial, and eukaryotic cytoplasmic isoleucyl tRNA synthetases; Region: Anticodon_Ia_Ile_ABEc; cd07961
707186000036	tRNA binding surface [nucleotide binding]; other site
707186000037	anticodon binding site; other site
707186000038	Signal peptidase I [Intracellular trafficking and secretion]; Region: LepB; COG0681
707186000039	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
707186000040	Catalytic site [active]
707186000041	signal peptidase I, bacterial type; Region: sigpep_I_bact; TIGR02227
707186000042	The S26 Type I signal peptidase (SPase; LepB; leader peptidase B; leader peptidase I; EC 3.4.21.89) family members are essential membrane-bound serine proteases that function to cleave the amino-terminal signal peptide extension from proteins that are...; Region: S26_SPase_I; cd06530
707186000043	50S ribosomal protein L31 type B; Reviewed; Region: rpmE2; PRK01678
707186000044	peptide chain release factor 1; Validated; Region: prfA; PRK00591
707186000045	PCRF domain; Region: PCRF; pfam03462
707186000046	RF-1 domain; Region: RF-1; pfam00472
707186000047	N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase; Provisional; Region: PRK09328
707186000048	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
707186000049	S-adenosylmethionine binding site [chemical binding]; other site
707186000050	signal recognition particle protein; Provisional; Region: PRK10867
707186000051	SRP54-type protein, helical bundle domain; Region: SRP54_N; smart00963
707186000052	The signal recognition particle (SRP) mediates the transport to or across the plasma membrane in bacteria and the endoplasmic reticulum in eukaryotes. SRP recognizes N-terminal sighnal sequences of newly synthesized polypeptides at the ribosome. The...; Region: SRP; cd03115
707186000053	P loop; other site
707186000054	GTP binding site [chemical binding]; other site
707186000055	Signal peptide binding domain; Region: SRP_SPB; pfam02978
707186000056	30S ribosomal protein S16; Provisional; Region: rpsP; PRK14522
707186000057	tRNA (guanine-N(1)-)-methyltransferase/unknown domain fusion protein; Reviewed; Region: trmD; PRK01037
707186000058	tRNA-(guanine-N1)-methyltransferase [Translation, ribosomal structure and biogenesis]; Region: TrmD; COG0336
707186000059	ribosomal protein L19, bacterial type; Region: rplS_bact; TIGR01024
707186000060	bacterial Ribonuclease HII-like; Region: RNase_HII_bacteria_HII_like; cd07182
707186000061	RNA/DNA hybrid binding site [nucleotide binding]; other site
707186000062	active site
707186000063	Guanylate kinase [Nucleotide transport and metabolism]; Region: Gmk; COG0194
707186000064	Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine...; Region: GMPK; cd00071
707186000065	catalytic site [active]
707186000066	G-X2-G-X-G-K; other site
707186000067	methionyl-tRNA synthetase; Reviewed; Region: PRK12268
707186000068	catalytic core domain of methioninyl-tRNA synthetases; Region: MetRS_core; cd00814
707186000069	active site
707186000070	HIGH motif; other site
707186000071	KMSKS motif; other site
707186000072	Anticodon-binding domain of methionyl tRNA synthetases; Region: Anticodon_Ia_Met; cd07957
707186000073	tRNA binding surface [nucleotide binding]; other site
707186000074	anticodon binding site; other site
707186000075	helicase, putative, RecD/TraA family; Region: recD_rel; TIGR01448
707186000076	AAA domain; Region: AAA_30; pfam13604
707186000077	Family description; Region: UvrD_C_2; pfam13538
707186000078	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
707186000079	Multidrug resistance efflux transporter; Region: EmrE; pfam13536
707186000080	Type 1 glutamine amidotransferase (GATase1)-like domain found in proteins similar to Saccharomyces cerevisiae biotin-apoprotein ligase (ScBLP); Region: GATase1_ScBLP_like; cd03144
707186000081	conserved cys residue [active]
707186000082	bifunctional aspartate kinase II/homoserine dehydrogenase II; Provisional; Region: metL; PRK09466
707186000083	Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the...; Region: AAT_I; cl00321
707186000084	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
707186000085	trimer interface [polypeptide binding]; other site
707186000086	active site
707186000087	Holliday junction resolvasome, helicase subunit [DNA replication, recombination, and repair]; Region: RuvB; COG2255
707186000088	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707186000089	Walker A motif; other site
707186000090	ATP binding site [chemical binding]; other site
707186000091	Walker B motif; other site
707186000092	arginine finger; other site
707186000093	Holliday junction DNA helicase ruvB C-terminus; Region: RuvB_C; pfam05491
707186000094	Type II secretory pathway, pullulanase PulA and related glycosidases [Carbohydrate transport and metabolism]; Region: PulA; COG1523
707186000095	N-terminal Early set domain associated with the catalytic domain of Glycogen debranching enzyme and bacterial isoamylase (also called glycogen 6-glucanohydrolase); Region: E_set_GDE_Isoamylase_N; cd02856
707186000096	Alpha amylase catalytic domain found in glycogen debranching enzymes; Region: AmyAc_Glg_debranch; cd11326
707186000097	active site
707186000098	catalytic site [active]
707186000099	Tir chaperone protein (CesT) family; Region: CesT; pfam05932
707186000100	Single-stranded DNA-binding protein [DNA replication, recombination, and repair]; Region: Ssb; COG0629
707186000101	SSB_OBF: A subfamily of OB folds similar to the OB fold of ssDNA-binding protein (SSB). SSBs bind with high affinity to ssDNA. They bind to and protect ssDNA intermediates during DNA metabolic pathways. All bacterial and eukaryotic SSBs studied to date...; Region: SSB_OBF; cd04496
707186000102	dimer interface [polypeptide binding]; other site
707186000103	ssDNA binding site [nucleotide binding]; other site
707186000104	tetramer (dimer of dimers) interface [polypeptide binding]; other site
707186000105	multifunctional aminopeptidase A; Provisional; Region: PRK00913
707186000106	Cytosol aminopeptidase family, N-terminal and catalytic domains.  Family M17 contains zinc- and manganese-dependent exopeptidases ( EC  3.4.11.1), including leucine aminopeptidase. They catalyze removal of amino acids from the N-terminus of a protein and...; Region: Peptidase_M17; cd00433
707186000107	interface (dimer of trimers) [polypeptide binding]; other site
707186000108	Substrate-binding/catalytic site; other site
707186000109	Zn-binding sites [ion binding]; other site
707186000110	hypothetical protein; Provisional; Region: PRK05907
707186000111	Predicted methyltransferases [General function prediction only]; Region: COG0313
707186000112	Uncharacterized subfamily of the tetrapyrrole methylase family similar to ribosomal RNA small subunit methyltransferase I (RsmI); Region: RsmI_like; cd11649
707186000113	putative SAM binding site [chemical binding]; other site
707186000114	homodimer interface [polypeptide binding]; other site
707186000115	coproporphyrinogen III oxidase; Provisional; Region: PRK06294
707186000116	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
707186000117	FeS/SAM binding site; other site
707186000118	HemN C-terminal domain; Region: HemN_C; pfam06969
707186000119	2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes [Energy production and conversion]; Region: SucA; COG0567
707186000120	Thiamine pyrophosphate (TPP) family, E1 of OGDC-like subfamily, TPP-binding module; composed of proteins similar to the E1 component of the 2-oxoglutarate dehydrogenase multienzyme complex (OGDC). OGDC catalyzes the oxidative decarboxylation of...; Region: TPP_E1_OGDC_like; cd02016
707186000121	TPP-binding site [chemical binding]; other site
707186000122	Transketolase, pyrimidine binding domain; Region: Transket_pyr; pfam02779
707186000123	dihydrolipoamide succinyltransferase; Validated; Region: PRK05704
707186000124	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
707186000125	E3 interaction surface; other site
707186000126	lipoyl attachment site [posttranslational modification]; other site
707186000127	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
707186000128	Multicopper polyphenol oxidase (laccase) [Secondary metabolites biosynthesis, transport and catabolism]; Region: yfiH; COG1496
707186000129	uncharacterized protein, YfiH family; Region: TIGR00726
707186000130	4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase; Validated; Region: PRK00694
707186000131	1-hydroxy-2-methyl-2-(e)-butenyl 4-diphosphate synthase [Lipid metabolism]; Region: gcpE; COG0821
707186000132	IncA protein; Region: IncA; pfam04156
707186000133	Macro domain, a high-affinity ADP-ribose binding module found in a variety of proteins as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Some macro domains recognize poly...; Region: Macro; cd02749
707186000134	ADP-ribose binding site [chemical binding]; other site
707186000135	Ferredoxin [Energy production and conversion]; Region: Fdx; COG0633
707186000136	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
707186000137	catalytic loop [active]
707186000138	iron binding site [ion binding]; other site
707186000139	type III secretion system protein; Validated; Region: PRK05910
707186000140	FHIPEP family; Region: FHIPEP; pfam00771
707186000141	RNA polymerase sigma factor sigma-28; Reviewed; Region: PRK05911
707186000142	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
707186000143	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
707186000144	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
707186000145	DNA binding residues [nucleotide binding]
707186000146	tyrosyl-tRNA synthetase; Validated; Region: PRK05912
707186000147	catalytic core domain of tyrosinyl-tRNA synthetase; Region: TyrRS_core; cd00805
707186000148	active site
707186000149	HIGH motif; other site
707186000150	dimer interface [polypeptide binding]; other site
707186000151	KMSKS motif; other site
707186000152	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
707186000153	RNA binding surface [nucleotide binding]; other site
707186000154	6-phosphogluconate dehydrogenase (decarboxylating); Region: gnd; TIGR00873
707186000155	6-phosphogluconate dehydrogenase-like protein; Reviewed; Region: PRK09599
707186000156	6-phosphogluconate dehydrogenase, C-terminal domain; Region: 6PGD; pfam00393
707186000157	GTP-binding protein LepA; Provisional; Region: PRK05433
707186000158	LepA also known as Elongation Factor 4 (EF4); Region: LepA; cd01890
707186000159	G1 box; other site
707186000160	putative GEF interaction site [polypeptide binding]; other site
707186000161	GTP/Mg2+ binding site [chemical binding]; other site
707186000162	Switch I region; other site
707186000163	G2 box; other site
707186000164	G3 box; other site
707186000165	Switch II region; other site
707186000166	G4 box; other site
707186000167	G5 box; other site
707186000168	lepA_II: This subfamily represents the domain II of LepA, a GTP-binding protein localized in the cytoplasmic membrane. The N-terminal domain of LepA shares regions of homology to translation factors. In terms of interaction with the ribosome, EF-G, EF-Tu...; Region: lepA_II; cd03699
707186000169	lepA_C: This family represents the C-terminal region of LepA, a GTP-binding protein localized in the cytoplasmic membrane.   LepA is ubiquitous in Bacteria and Eukaryota (e.g. Saccharomyces cerevisiae GUF1p), but is missing from Archaea. LepA exhibits...; Region: lepA_C; cd03709
707186000170	GTP-binding protein LepA C-terminus; Region: LepA_C; pfam06421
707186000171	ADP/ATP carrier protein family; Region: AAA; TIGR00769
707186000172	ABC-type metal ion transport system, periplasmic component/surface adhesin [Inorganic ion transport and metabolism]; Region: LraI; COG0803
707186000173	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
707186000174	intersubunit interface [polypeptide binding]; other site
707186000175	ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism]; Region: ZnuC; COG1121
707186000176	ATP-binding cassette domain of the metal-type transporters; Region: ABC_Metallic_Cations; cd03235
707186000177	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
707186000178	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
707186000179	ABC-ATPase subunit  interface; other site
707186000180	dimer interface [polypeptide binding]; other site
707186000181	putative PBP binding regions; other site
707186000182	Mn-dependent transcriptional regulator [Transcription]; Region: TroR; COG1321
707186000183	Iron dependent repressor, metal binding and dimerisation domain; Region: Fe_dep_repr_C; pfam02742
707186000184	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
707186000185	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
707186000186	ABC-ATPase subunit  interface; other site
707186000187	dimer interface [polypeptide binding]; other site
707186000188	putative PBP binding regions; other site
707186000189	1-deoxy-D-xylulose 5-phosphate reductoisomerase [Lipid metabolism]; Region: Dxr; COG0743
707186000190	1-deoxy-D-xylulose 5-phosphate reductoisomerase; Region: DXP_reductoisom; pfam02670
707186000191	1-deoxy-D-xylulose 5-phosphate reductoisomerase C-terminal; Region: DXP_redisom_C; pfam08436
707186000192	DXP reductoisomerase C-terminal domain; Region: DXPR_C; pfam13288
707186000193	RIP metalloprotease RseP; Region: TIGR00054
707186000194	RseP-like Site-2 proteases (S2P), zinc metalloproteases (MEROPS family M50A), cleave transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. In Escherichia coli, the S2P homolog...; Region: S2P-M50_PDZ_RseP-like; cd06163
707186000195	active site
707186000196	Predicted membrane-associated Zn-dependent proteases 1 [Cell envelope biogenesis, outer membrane]; Region: COG0750
707186000197	Site-2 protease (S2P) class of zinc metalloproteases (MEROPS family M50) cleaves transmembrane domains of substrate proteins, regulating intramembrane proteolysis (RIP) of diverse signal transduction mechanisms. Members of this family use proteolytic...; Region: S2P-M50; cl10020
707186000198	putative substrate binding region [chemical binding]; other site
707186000199	Alpha/beta hydrolase family; Region: Abhydrolase_5; pfam12695
707186000200	Putative serine esterase (DUF676); Region: DUF676; pfam05057
707186000201	recF protein; Region: recf; TIGR00611
707186000202	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707186000203	Walker A/P-loop; other site
707186000204	ATP binding site [chemical binding]; other site
707186000205	Q-loop/lid; other site
707186000206	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707186000207	ABC transporter signature motif; other site
707186000208	Walker B; other site
707186000209	DNA polymerase III subunit beta; Validated; Region: PRK05643
707186000210	Beta clamp domain.  The beta subunit (processivity factor) of DNA polymerase III holoenzyme, refered to as the beta clamp, forms a ring shaped dimer that encircles dsDNA (sliding clamp) in bacteria.  The beta-clamp is structurally similar to the trimeric...; Region: beta_clamp; cd00140
707186000211	putative DNA binding surface [nucleotide binding]; other site
707186000212	dimer interface [polypeptide binding]; other site
707186000213	beta-clamp/clamp loader binding surface; other site
707186000214	beta-clamp/translesion DNA polymerase binding surface; other site
707186000215	Small protein B (SmpB) is a component of the trans-translation system in prokaryotes for releasing stalled ribosome from damaged messenger RNAs; Region: SmpB; cd09294
707186000216	SmpB-tmRNA interface; other site
707186000217	Membrane-associated lipoprotein involved in thiamine biosynthesis [Coenzyme metabolism]; Region: ApbE; COG1477
707186000218	ApbE family; Region: ApbE; pfam02424
707186000219	bifunctional 5,10-methylene-tetrahydrofolate dehydrogenase/ 5,10-methylene-tetrahydrofolate cyclohydrolase; Provisional; Region: PRK14181
707186000220	Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain; Region: THF_DHG_CYH; pfam00763
707186000221	NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase; Region: NAD_bind_m-THF_DH_Cyclohyd; cd01080
707186000222	homodimer interface [polypeptide binding]; other site
707186000223	NADP binding site [chemical binding]; other site
707186000224	substrate binding site [chemical binding]; other site
707186000225	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
707186000226	PLD-like domain; Region: PLDc_2; pfam13091
707186000227	putative active site [active]
707186000228	catalytic site [active]
707186000229	Catalytic domain of EDTA-resistant nuclease Nuc, vertebrate phospholipase D6, and similar proteins; Region: PLDc_Nuc_like; cd09116
707186000230	PLD-like domain; Region: PLDc_2; pfam13091
707186000231	putative active site [active]
707186000232	catalytic site [active]
707186000233	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; cl00311
707186000234	3-octaprenyl-4-hydroxybenzoate carboxy-lyase; Region: UbiD; cl00311
707186000235	50S ribosomal protein L28; Reviewed; Region: rpmB; PRK00359
707186000236	potential frameshift: common BLAST hit: gi|166155183|ref|YP_001653438.1| 4-alpha-glucanotransferase
707186000237	Tir chaperone protein (CesT) family; Region: CesT; pfam05932
707186000238	HrpJ-like domain; Region: HrpJ; cl15454
707186000239	Type III secretory pathway, component EscV [Intracellular trafficking and secretion]; Region: EscV; COG4789
707186000240	FHIPEP family; Region: FHIPEP; pfam00771
707186000241	type III secretion system protein; Validated; Region: PRK06298
707186000242	Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB [Function unknown]; Region: COG2257; cl15822
707186000243	GTP-binding protein YchF; Reviewed; Region: PRK09601
707186000244	YchF GTPase; Region: YchF; cd01900
707186000245	G1 box; other site
707186000246	GTP/Mg2+ binding site [chemical binding]; other site
707186000247	Switch I region; other site
707186000248	G2 box; other site
707186000249	Switch II region; other site
707186000250	G3 box; other site
707186000251	G4 box; other site
707186000252	G5 box; other site
707186000253	TGS_YchF_C: This subfamily represents TGS domain-containing YchF GTP-binding protein, a universally conserved GTPase whose function is unknown. The N-terminal domain of the YchF protein belongs to the Obg-like family of GTPases, and some members of the...; Region: TGS_YchF_C; cd04867
707186000254	FAD synthase [Coenzyme metabolism]; Region: RibF; COG0196
707186000255	FAD synthetase, N-terminal domain of the bifunctional enzyme; Region: FAD_synthetase_N; cd02064
707186000256	active site
707186000257	Riboflavin kinase; Region: Flavokinase; smart00904
707186000258	tRNA pseudouridine synthase B; Provisional; Region: truB; PRK00989
707186000259	Pseudouridine synthase, Escherichia coli TruB like; Region: PseudoU_synth_EcTruB; cd02573
707186000260	RNA binding site [nucleotide binding]; other site
707186000261	active site
707186000262	ribosome-binding factor A; Validated; Region: rbfA; PRK00521
707186000263	Translation initiation factor IF-2, N-terminal region; Region: IF2_N; pfam04760
707186000264	Translation initiation factor 2 (IF-2; GTPase) [Translation, ribosomal structure and biogenesis]; Region: InfB; COG0532
707186000265	Initiation Factor 2 (IF2)/ eukaryotic Initiation Factor 5B (eIF5B) family; Region: IF2_eIF5B; cd01887
707186000266	G1 box; other site
707186000267	putative GEF interaction site [polypeptide binding]; other site
707186000268	GTP/Mg2+ binding site [chemical binding]; other site
707186000269	Switch I region; other site
707186000270	G2 box; other site
707186000271	G3 box; other site
707186000272	Switch II region; other site
707186000273	G4 box; other site
707186000274	G5 box; other site
707186000275	This family represents the domain II of bacterial Initiation Factor 2 (IF2) and its eukaryotic mitochondrial homologue mtIF2. IF2, the largest initiation factor is an essential GTP binding protein. In E. coli three natural forms of IF2 exist in the cell; Region: IF2_mtIF2_II; cd03702
707186000276	Translation-initiation factor 2; Region: IF-2; pfam11987
707186000277	mtIF2_IVc: this family represents the C2 subdomain of domain IV of mitochondrial translation initiation factor 2 (mtIF2) which adopts a beta-barrel fold displaying a high degree of structural similarity with domain II of the translation elongation factor...; Region: mtIF2_IVc; cd03692
707186000278	transcription termination factor NusA; Region: NusA; TIGR01953
707186000279	NusA N-terminal domain; Region: NusA_N; pfam08529
707186000280	S1_NusA: N-utilizing substance A protein (NusA), S1-like RNA-binding domain. S1-like RNA-binding domains are found in a wide variety of RNA-associated proteins. NusA is a transcription elongation factor containing an N-terminal catalytic domain and three...; Region: S1_NusA; cd04455
707186000281	RNA binding site [nucleotide binding]; other site
707186000282	homodimer interface [polypeptide binding]; other site
707186000283	NusA-like KH domain; Region: KH_5; pfam13184
707186000284	NusA_K homology RNA-binding domain (KH). NusA is an essential multifunctional transcription elongation factor that is universally conserved among prokaryotes and archaea. NusA anti-termination function plays an important role in the expression of...; Region: NusA_KH; cd02134
707186000285	G-X-X-G motif; other site
707186000286	30S ribosomal protein S1; Reviewed; Region: rpsA; PRK06299
707186000287	S1_RPS1_repeat_ec1_hs1: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec1_hs1; cd05687
707186000288	RNA binding site [nucleotide binding]; other site
707186000289	S1_RPS1_repeat_ec2_hs2: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture...; Region: S1_RPS1_repeat_ec2_hs2; cd04465
707186000290	RNA binding site [nucleotide binding]; other site
707186000291	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
707186000292	RNA binding site [nucleotide binding]; other site
707186000293	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
707186000294	RNA binding site [nucleotide binding]; other site
707186000295	S1_RPS1_repeat_ec5: Ribosomal protein S1 (RPS1) domain. RPS1 is a component of the small ribosomal subunit thought to be involved in the recognition and binding of mRNA's during translation initiation. The bacterial RPS1 domain architecture consists...; Region: S1_RPS1_repeat_ec5; cd05690
707186000296	RNA binding site [nucleotide binding]; other site
707186000297	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
707186000298	RNA binding site [nucleotide binding]; other site
707186000299	domain interface; other site
707186000300	thioredoxin-disulfide reductase; Region: TRX_reduct; TIGR01292
707186000301	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
707186000302	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
707186000303	4'-phosphopantetheinyl transferase; Provisional; Region: acpS; PRK00070
707186000304	Flagellar biogenesis protein [Cell motility and secretion]; Region: FliO; COG3190
707186000305	Predicted hydrolases of the HAD superfamily [General function prediction only]; Region: Cof; COG0561
707186000306	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cl17915
707186000307	active site
707186000308	motif I; other site
707186000309	motif II; other site
707186000310	enoyl-[acyl-carrier-protein] reductase; Region: PLN02730
707186000311	Enoyl acyl carrier protein (ACP) reductase (ENR), divergent SDR; Region: ENR_SDR; cd05372
707186000312	NAD binding site [chemical binding]; other site
707186000313	homotetramer interface [polypeptide binding]; other site
707186000314	homodimer interface [polypeptide binding]; other site
707186000315	substrate binding site [chemical binding]; other site
707186000316	active site
707186000317	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
707186000318	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
707186000319	RNA binding surface [nucleotide binding]; other site
707186000320	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
707186000321	active site
707186000322	A/G-specific adenine glycosylase; Region: mutY; TIGR01084
707186000323	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
707186000324	minor groove reading motif; other site
707186000325	helix-hairpin-helix signature motif; other site
707186000326	substrate binding pocket [chemical binding]; other site
707186000327	active site
707186000328	iron-sulpphur binding domain in DNA-(apurinic or apyrimidinic site) lyase (subfamily of ENDO3); Region: FES; smart00525
707186000329	DNA glycosylase (MutY in bacteria and hMYH in humans) is responsible for repairing misread  A*oxoG residues to C*G by removing the inappropriately paired adenine base from the DNA backbone. It belongs to the Nudix hydrolase superfamily and is important...; Region: DNA_Glycosylase_C; cd03431
707186000330	DNA binding and oxoG recognition site [nucleotide binding]
707186000331	Uncharacterized conserved protein [Function unknown]; Region: COG0327
707186000332	NIF3 (NGG1p interacting factor 3); Region: NIF3; pfam01784
707186000333	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
707186000334	GroEL_like type I chaperonin. Chaperonins are involved in productive folding of proteins. They share a common general morphology, a double toroid of 2 stacked rings, each composed of 7-9 subunits. The symmetry of type I is seven-fold and they are found...; Region: GroEL; cd03344
707186000335	ring oligomerisation interface [polypeptide binding]; other site
707186000336	ATP/Mg binding site [chemical binding]; other site
707186000337	stacking interactions; other site
707186000338	hinge regions; other site
707186000339	Chaperonin 10 Kd subunit (cpn10 or GroES); Cpn10 cooperates with chaperonin 60 (cpn60 or GroEL), an ATPase, to assist the folding and assembly of proteins and is found in eubacterial cytosol, as well as in the matrix of mitochondria and chloroplasts. It...; Region: cpn10; cd00320
707186000340	oligomerisation interface [polypeptide binding]; other site
707186000341	mobile loop; other site
707186000342	roof hairpin; other site
707186000343	Oligoendopeptidase F [Amino acid transport and metabolism]; Region: COG1164
707186000344	Peptidase family M3B Oligopeptidase F (PepF); Region: M3B_PepF_3; cd09608
707186000345	active site
707186000346	Zn binding site [ion binding]; other site
707186000347	ATP-dependent chaperone ClpB; Region: chaperone_ClpB; TIGR03346
707186000348	Clp amino terminal domain; Region: Clp_N; pfam02861
707186000349	Clp amino terminal domain; Region: Clp_N; pfam02861
707186000350	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707186000351	Walker A motif; other site
707186000352	ATP binding site [chemical binding]; other site
707186000353	Walker B motif; other site
707186000354	arginine finger; other site
707186000355	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707186000356	Walker A motif; other site
707186000357	ATP binding site [chemical binding]; other site
707186000358	Walker B motif; other site
707186000359	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
707186000360	Uncharacterized conserved protein [Function unknown]; Region: COG2912
707186000361	Transglutaminase-like superfamily; Region: Transglut_core2; pfam13369
707186000362	IncA protein; Region: IncA; pfam04156
707186000363	Ribulose-5-phosphate 3-epimerase (RPE). This enzyme catalyses the interconversion of D-ribulose 5-phosphate (Ru5P) into D-xylulose 5-phosphate, as part of the Calvin cycle (reductive pentose phosphate pathway) in chloroplasts and in the oxidative pentose...; Region: RPE; cd00429
707186000364	ribulose-phosphate 3-epimerase; Region: rpe; TIGR01163
707186000365	substrate binding site [chemical binding]; other site
707186000366	hexamer interface [polypeptide binding]; other site
707186000367	metal binding site [ion binding]; metal-binding site
707186000368	elongation factor P; Provisional; Region: PRK12426
707186000369	S1_like: Ribosomal protein S1-like RNA-binding domain. Found in a wide variety of RNA-associated proteins. Originally identified in S1 ribosomal protein. This superfamily also contains the Cold Shock Domain (CSD), which is a homolog of the S1 domain; Region: S1_like; cl09927
707186000370	RNA binding site [nucleotide binding]; other site
707186000371	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
707186000372	RNA binding site [nucleotide binding]; other site
707186000373	acetyl-CoA carboxylase biotin carboxyl carrier protein subunit; Validated; Region: PRK06302
707186000374	The biotinyl-domain or biotin carboxyl carrier protein (BCCP) domain is present in all biotin-dependent enzymes, such as acetyl-CoA carboxylase, pyruvate carboxylase, propionyl-CoA carboxylase, methylcrotonyl-CoA carboxylase, geranyl-CoA carboxylase; Region: biotinyl_domain; cd06850
707186000375	carboxyltransferase (CT) interaction site; other site
707186000376	biotinylation site [posttranslational modification]; other site
707186000377	acetyl-CoA carboxylase biotin carboxylase subunit; Validated; Region: PRK08591
707186000378	Carbamoyl-phosphate synthase L chain, N-terminal domain; Region: CPSase_L_chain; pfam00289
707186000379	ATP-grasp domain; Region: ATP-grasp_4; cl17255
707186000380	Biotin carboxylase C-terminal domain; Region: Biotin_carb_C; smart00878
707186000381	Ribosomal protein L13.  Protein L13, a large ribosomal subunit protein, is one of five proteins required for an early folding intermediate of 23S rRNA in the assembly of the large subunit. L13 is situated on the bottom of the large subunit, near the...; Region: Ribosomal_L13; cd00392
707186000382	23S rRNA interface [nucleotide binding]; other site
707186000383	L3 interface [polypeptide binding]; other site
707186000384	30S ribosomal protein S9; Reviewed; Region: rpsI; PRK00132
707186000385	Cell wall-associated hydrolases (invasion-associated proteins) [Cell envelope biogenesis, outer membrane]; Region: Spr; COG0791
707186000386	NlpC/P60 family; Region: NLPC_P60; cl17555
707186000387	adenylate kinase; Reviewed; Region: adk; PRK00279
707186000388	Adenylate kinase (ADK) catalyzes the reversible phosphoryl transfer from adenosine triphosphates (ATP) to adenosine monophosphates (AMP) and to yield adenosine diphosphates (ADP). This enzyme is required for the biosynthesis of ADP and is essential for...; Region: ADK; cd01428
707186000389	AMP-binding site [chemical binding]; other site
707186000390	ATP-AMP (Ap5A)-binding site [chemical binding]; other site
707186000391	ABC-type arginine transport system, permease component [Amino acid transport and metabolism]; Region: ArtQ; COG4215
707186000392	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
707186000393	dimer interface [polypeptide binding]; other site
707186000394	conserved gate region; other site
707186000395	putative PBP binding loops; other site
707186000396	ABC-ATPase subunit interface; other site
707186000397	ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism]; Region: GlnQ; COG1126
707186000398	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707186000399	Walker A/P-loop; other site
707186000400	ATP binding site [chemical binding]; other site
707186000401	Q-loop/lid; other site
707186000402	ABC transporter signature motif; other site
707186000403	Walker B; other site
707186000404	D-loop; other site
707186000405	H-loop/switch region; other site
707186000406	Ribonuclease BN family enzyme [Replication, recombination, and repair]; Region: Rbn; COG1295
707186000407	Methyltransferase domain; Region: Methyltransf_23; pfam13489
707186000408	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
707186000409	S-adenosylmethionine binding site [chemical binding]; other site
707186000410	Phospholipase/Carboxylesterase; Region: Abhydrolase_2; pfam02230
707186000411	Serine hydrolase (FSH1); Region: FSH1; pfam03959
707186000412	Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis]; Region: SUA5; COG0009
707186000413	Zn-dependent dipeptidase, microsomal dipeptidase homolog [Amino acid transport and metabolism]; Region: COG2355
707186000414	Superfamily of metallo-dependent hydrolases (also called amidohydrolase superfamily) is a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a...; Region: metallo-dependent_hydrolases; cl00281
707186000415	active site
707186000416	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
707186000417	Bacterial extracellular solute-binding proteins, family 5 Middle; Region: SBP_bac_5; pfam00496
707186000418	conserved hypothetical integral membrane protein; Region: TIGR00697
707186000419	Predicted metal-binding protein related to the C-terminal domain of SecA [General function prediction only]; Region: COG3318
707186000420	SEC-C motif; Region: SEC-C; pfam02810
707186000421	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
707186000422	Catalytic domain of Protein Kinases; Region: PKc; cd00180
707186000423	active site
707186000424	ATP binding site [chemical binding]; other site
707186000425	substrate binding site [chemical binding]; other site
707186000426	activation loop (A-loop); other site
707186000427	Uncharacterized conserved protein [Function unknown]; Region: COG1262
707186000428	Formylglycine-generating sulfatase enzyme; Region: FGE-sulfatase; pfam03781
707186000429	NAD+ dependent DNA ligase adenylation domain. DNA ligases catalyze the crucial step of joining the breaks in duplex DNA during DNA replication, repair and recombination, utilizing either ATP or NAD(+) as a cofactor, but using the same basic reaction...; Region: LIGANc; cd00114
707186000430	DNA ligase, NAD-dependent; Region: dnlj; TIGR00575
707186000431	nucleotide binding pocket [chemical binding]; other site
707186000432	K-X-D-G motif; other site
707186000433	catalytic site [active]
707186000434	NAD-dependent DNA ligase OB-fold domain; Region: DNA_ligase_OB; pfam03120
707186000435	NAD-dependent DNA ligase C4 zinc finger domain; Region: DNA_ligase_ZBD; pfam03119
707186000436	Helix-hairpin-helix motif; Region: HHH; pfam00633
707186000437	helix-hairpin-helix signature motif; other site
707186000438	Breast Cancer Suppressor Protein (BRCA1), carboxy-terminal domain. The BRCT domain is found within many DNA damage repair and cell cycle checkpoint proteins. The unique diversity of this domain superfamily allows BRCT modules to interact forming homo...; Region: BRCT; cd00027
707186000439	Dimer interface [polypeptide binding]; other site
707186000440	BRCT sequence motif; other site
707186000441	hypothetical protein; Provisional; Region: PRK06184
707186000442	Hydrolases of the alpha/beta superfamily [General function prediction only]; Region: COG1073
707186000443	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
707186000444	50S ribosomal protein L33; Validated; Region: rpmG; PRK00595
707186000445	ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms]; Region: SalY; COG0577
707186000446	FtsX-like permease family; Region: FtsX; pfam02687
707186000447	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
707186000448	ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein; Region: ABC_MJ0796_LolCDE_FtsE; cd03255
707186000449	Walker A/P-loop; other site
707186000450	ATP binding site [chemical binding]; other site
707186000451	Q-loop/lid; other site
707186000452	ABC transporter signature motif; other site
707186000453	Walker B; other site
707186000454	D-loop; other site
707186000455	H-loop/switch region; other site
707186000456	membrane-attack complex / perforin; Region: MACPF; smart00457
707186000457	Domain in ryanodine and inositol trisphosphate receptors and protein O-mannosyltransferases; Region: MIR; smart00472
707186000458	PLD-like domain; Region: PLDc_2; pfam13091
707186000459	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
707186000460	putative active site [active]
707186000461	catalytic site [active]
707186000462	Catalytic domain of EDTA-resistant nuclease Nuc, vertebrate phospholipase D6, and similar proteins; Region: PLDc_Nuc_like; cd09116
707186000463	PLD-like domain; Region: PLDc_2; pfam13091
707186000464	putative active site [active]
707186000465	catalytic site [active]
707186000466	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
707186000467	PLD-like domain; Region: PLDc_2; pfam13091
707186000468	putative active site [active]
707186000469	catalytic site [active]
707186000470	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
707186000471	PLD-like domain; Region: PLDc_2; pfam13091
707186000472	putative active site [active]
707186000473	catalytic site [active]
707186000474	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
707186000475	PLD-like domain; Region: PLDc_2; pfam13091
707186000476	putative active site [active]
707186000477	catalytic site [active]
707186000478	Catalytic domain of EDTA-resistant nuclease Nuc, vertebrate phospholipase D6, and similar proteins; Region: PLDc_Nuc_like; cd09116
707186000479	PLD-like domain; Region: PLDc_2; pfam13091
707186000480	putative active site [active]
707186000481	catalytic site [active]
707186000482	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
707186000483	potential frameshift: common BLAST hit: gi|15835056|ref|NP_296815.1| adherence factor
707186000484	TcdB toxin N-terminal helical domain; Region: TcdB_N; pfam12918
707186000485	TcdA/TcdB catalytic glycosyltransferase domain; Region: TcdA_TcdB; pfam12919
707186000486	Glycosyltransferase sugar-binding region containing DXD motif; Region: Gly_transf_sug; pfam04488
707186000487	Protein of unknown function (DUF3491); Region: DUF3491; pfam11996
707186000488	trp operon repressor, proteobacterial; Region: TrpR; TIGR01321
707186000489	tryptophan synthase, beta subunit; Region: trpB; TIGR00263
707186000490	Tryptophan synthase-beta:  Trptophan synthase is a bifunctional enzyme that catalyses the last two steps in the biosynthesis of L-tryptophan via its alpha and beta reactions. In the alpha reaction, indole 3-glycerol phosphate is cleaved reversibly to...; Region: Trp-synth_B; cd06446
707186000491	pyridoxal 5'-phosphate binding site [chemical binding]; other site
707186000492	catalytic residue [active]
707186000493	tryptophan synthase alpha subunit; Provisional; Region: trpA; CHL00200
707186000494	Ttryptophan synthase (TRPS) alpha subunit (TSA). TPRS is a bifunctional tetrameric enzyme (2 alpha and 2 beta subunits) that catalyzes the last two steps of L-tryptophan biosynthesis. Alpha and beta subunit catalyze two distinct reactions which are both...; Region: Tryptophan_synthase_alpha; cd04724
707186000495	substrate binding site [chemical binding]; other site
707186000496	active site
707186000497	catalytic residues [active]
707186000498	heterodimer interface [polypeptide binding]; other site
707186000499	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
707186000500	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
707186000501	peptide binding site [polypeptide binding]; other site
707186000502	putative disulfide oxidoreductase; Provisional; Region: PRK00611
707186000503	Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones]; Region: DsbG; COG1651
707186000504	Thioredoxin; Region: Thioredoxin_4; cl17273
707186000505	Vitamin K epoxide reductase (VKOR) family; Region: VKOR; cl01729
707186000506	putative active site [active]
707186000507	redox center [active]
707186000508	ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism]; Region: TauB; COG1116
707186000509	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707186000510	Walker A/P-loop; other site
707186000511	ATP binding site [chemical binding]; other site
707186000512	Q-loop/lid; other site
707186000513	ABC transporter signature motif; other site
707186000514	Walker B; other site
707186000515	D-loop; other site
707186000516	H-loop/switch region; other site
707186000517	3-deoxy-manno-octulosonate cytidylyltransferase; Provisional; Region: PRK05450
707186000518	CMP-KDO synthetase catalyzes the activation of KDO which is an essential component of the lipopolysaccharide; Region: CMP-KDO-Synthetase; cd02517
707186000519	Ligand binding site; other site
707186000520	oligomer interface; other site
707186000521	CTP synthetase; Validated; Region: pyrG; PRK05380
707186000522	CTP synthetase (CTPs) is a two-domain protein, which consists of an N-terminal synthetase domain and C-terminal glutaminase domain. The enzymes hydrolyze the amide bond of glutamine to ammonia and glutamate at the glutaminase domains and transfer nascent...; Region: CTGs; cd03113
707186000523	Catalytic site [active]
707186000524	active site
707186000525	UTP binding site [chemical binding]; other site
707186000526	Type 1 glutamine amidotransferase (GATase1) domain found in Cytidine Triphosphate Synthetase; Region: GATase1_CTP_Synthase; cd01746
707186000527	active site
707186000528	putative oxyanion hole; other site
707186000529	catalytic triad [active]
707186000530	Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) [DNA replication, recombination, and repair]; Region: COG0816
707186000531	glucose-6-phosphate 1-dehydrogenase; Validated; Region: PRK05722
707186000532	Glucose-6-phosphate dehydrogenase, NAD binding domain; Region: G6PD_N; pfam00479
707186000533	Glucose-6-phosphate dehydrogenase, C-terminal domain; Region: G6PD_C; pfam02781
707186000534	6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase [Carbohydrate transport and metabolism]; Region: NagB; COG0363
707186000535	6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard...; Region: 6PGL; cd01400
707186000536	putative active site [active]
707186000537	DNA polymerase III subunit delta'; Validated; Region: PRK05917
707186000538	DNA polymerase III subunit delta'; Validated; Region: PRK08485
707186000539	thymidylate kinase; Validated; Region: tmk; PRK00698
707186000540	Thymidine monophosphate kinase (TMPK), also known as thymidylate kinase, catalyzes the phosphorylation of thymidine monophosphate (TMP) to thymidine diphosphate (TDP) utilizing ATP as its preferred phophoryl donor. TMPK represents the rate-limiting step...; Region: TMPK; cd01672
707186000541	TMP-binding site; other site
707186000542	ATP-binding site [chemical binding]; other site
707186000543	DNA gyrase, A subunit; Region: gyrA; TIGR01063
707186000544	DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes...; Region: TOP4c; cd00187
707186000545	CAP-like domain; other site
707186000546	active site
707186000547	primary dimer interface [polypeptide binding]; other site
707186000548	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
707186000549	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
707186000550	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
707186000551	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
707186000552	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
707186000553	DNA gyrase C-terminal domain, beta-propeller; Region: DNA_gyraseA_C; pfam03989
707186000554	DNA gyrase subunit B; Provisional; Region: gyrB; PRK14939
707186000555	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
707186000556	ATP binding site [chemical binding]; other site
707186000557	Mg2+ binding site [ion binding]; other site
707186000558	G-X-G motif; other site
707186000559	TopoIIA_Trans_DNA_gyrase: Transducer domain, having a ribosomal S5 domain 2-like fold, of the type found in proteins of the type IIA family of DNA topoisomerases similar to the B subunits of E. coli DNA gyrase and E. coli Topoisomerase IV which are; Region: TopoII_Trans_DNA_gyrase; cd00822
707186000560	anchoring element; other site
707186000561	dimer interface [polypeptide binding]; other site
707186000562	ATP binding site [chemical binding]; other site
707186000563	TOPRIM_TopoIIA_GyrB: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to the Escherichia coli GyrB subunit. TopoIIA enzymes cut both strands of the...; Region: TOPRIM_TopoIIA_GyrB; cd03366
707186000564	active site
707186000565	putative metal-binding site [ion binding]; other site
707186000566	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
707186000567	Protein of unknown function (DUF721); Region: DUF721; pfam05258
707186000568	queuine tRNA-ribosyltransferase; Provisional; Region: PRK01008
707186000569	Queuine/archaeosine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]; Region: Tgt; COG0343
707186000570	Mg/Co/Ni transporter MgtE (contains CBS domain) [Inorganic ion transport and metabolism]; Region: MgtE; COG2239
707186000571	MgtE intracellular N domain; Region: MgtE_N; pfam03448
707186000572	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domain in the magnesium transporter, MgtE.  MgtE and its homologs are found in eubacteria, archaebacteria, and eukaryota. Members of this family transport Mg2+ or other...; Region: CBS_pair_Mg_transporter; cd04606
707186000573	Divalent cation transporter; Region: MgtE; pfam01769
707186000574	Metal-dependent proteases with possible chaperone activity [Posttranslational modification, protein turnover, chaperones]; Region: QRI7; COG0533
707186000575	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214; cl17884
707186000576	Nucleotide-Binding Domain of the sugar kinase/HSP70/actin superfamily; Region: NBD_sugar-kinase_HSP70_actin; cl17037
707186000577	ABC-type oligopeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: OppA; COG4166
707186000578	The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold; Region: PBP2_OppA; cd08504
707186000579	peptide binding site [polypeptide binding]; other site
707186000580	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
707186000581	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
707186000582	dimer interface [polypeptide binding]; other site
707186000583	conserved gate region; other site
707186000584	putative PBP binding loops; other site
707186000585	ABC-ATPase subunit interface; other site
707186000586	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
707186000587	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
707186000588	dimer interface [polypeptide binding]; other site
707186000589	conserved gate region; other site
707186000590	putative PBP binding loops; other site
707186000591	ABC-ATPase subunit interface; other site
707186000592	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
707186000593	nickel import ATP-binding protein NikD; Region: nickel_nikD; TIGR02770
707186000594	Walker A/P-loop; other site
707186000595	ATP binding site [chemical binding]; other site
707186000596	Q-loop/lid; other site
707186000597	ABC transporter signature motif; other site
707186000598	Walker B; other site
707186000599	D-loop; other site
707186000600	H-loop/switch region; other site
707186000601	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; pfam08352
707186000602	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
707186000603	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
707186000604	Walker A/P-loop; other site
707186000605	ATP binding site [chemical binding]; other site
707186000606	Q-loop/lid; other site
707186000607	ABC transporter signature motif; other site
707186000608	Walker B; other site
707186000609	D-loop; other site
707186000610	H-loop/switch region; other site
707186000611	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
707186000612	Protein of unknown function (DUF1186); Region: DUF1186; pfam06685
707186000613	Di- and tricarboxylate transporters [Inorganic ion transport and metabolism]; Region: CitT; COG0471
707186000614	Anion permease ArsB/NhaD.  These permeases have been shown to translocate sodium, arsenate, antimonite, sulfate and organic anions across biological membranes in all three kingdoms of life.  A typical anion permease contains 8-13 transmembrane helices...; Region: ArsB_NhaD_permease; cd00625
707186000615	transmembrane helices; other site
707186000616	diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional; Region: PRK07085
707186000617	active site
707186000618	ADP/pyrophosphate binding site [chemical binding]; other site
707186000619	dimerization interface [polypeptide binding]; other site
707186000620	allosteric effector site; other site
707186000621	fructose-1,6-bisphosphate binding site; other site
707186000622	Putative lysophospholipase; Region: Hydrolase_4; pfam12146
707186000623	Alpha/beta hydrolase family; Region: Abhydrolase_6; pfam12697
707186000624	diphosphate--fructose-6-phosphate 1-phosphotransferase; Provisional; Region: PRK07085
707186000625	pyrophosphate-dependent phosphofructokinase; Region: PLN02251
707186000626	active site
707186000627	ADP/pyrophosphate binding site [chemical binding]; other site
707186000628	dimerization interface [polypeptide binding]; other site
707186000629	allosteric effector site; other site
707186000630	fructose-1,6-bisphosphate binding site; other site
707186000631	3-deoxy-D-manno-octulosonic-acid transferase [Cell envelope biogenesis, outer membrane]; Region: KdtA; COG1519
707186000632	3-Deoxy-D-manno-octulosonic-acid transferase (kdotransferase); Region: Glycos_transf_N; pfam04413
707186000633	leucyl-tRNA synthetase; Validated; Region: leuS; PRK00390
707186000634	catalytic core domain of leucyl-tRNA synthetases; Region: LeuRS_core; cd00812
707186000635	HIGH motif; other site
707186000636	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
707186000637	nucleotidyl transferase superfamily; Region: nt_trans; cl00015
707186000638	active site
707186000639	KMSKS motif; other site
707186000640	Anticodon-binding domain of bacterial and eukaryotic mitochondrial leucyl tRNA synthetases; Region: Anticodon_Ia_Leu_BEm; cd07958
707186000641	tRNA binding surface [nucleotide binding]; other site
707186000642	glutamate-1-semialdehyde aminotransferase; Provisional; Region: PRK00615
707186000643	Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase; Region: OAT_like; cd00610
707186000644	inhibitor-cofactor binding pocket; inhibition site
707186000645	pyridoxal 5'-phosphate binding site [chemical binding]; other site
707186000646	catalytic residue [active]
707186000647	Putative transcriptional regulator [Transcription]; Region: COG1678
707186000648	Uncharacterized conserved protein [Function unknown]; Region: COG1259
707186000649	RPI_A: Ribose 5-phosphate isomerase type A (RPI_A) subfamily; RPI catalyzes the reversible conversion of ribose-5-phosphate to ribulose 5-phosphate, the first step of the non-oxidative branch of the pentose phosphate pathway. This reaction leads to the...; Region: RPI_A; cd01398
707186000650	tetramer (dimer of dimers) interface [polypeptide binding]; other site
707186000651	active site
707186000652	dimer interface [polypeptide binding]; other site
707186000653	fructose-bisphosphate aldolase; Provisional; Region: PRK09250
707186000654	Class I fructose-1,6-bisphosphate (FBP) aldolases of the archaeal type (DhnA homologs); Region: DhnA; cd00958
707186000655	putative active site; other site
707186000656	catalytic residue [active]
707186000657	putative glutamate/gamma-aminobutyrate antiporter; Region: put_Glu_GABA_T; TIGR03813
707186000658	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
707186000659	This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily  includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which  binds to Adenosine group.  This subfamily; Region: Alpha_ANH_like_II; cd01993
707186000660	Ligand Binding Site [chemical binding]; other site
707186000661	Predicted acid phosphatase [General function prediction only]; Region: SurE; COG0496
707186000662	prenyltransferase; Reviewed; Region: ubiA; PRK12876
707186000663	UbiA prenyltransferase family; Region: UbiA; pfam01040
707186000664	aromatic acid decarboxylase; Validated; Region: PRK05920
707186000665	Flavoprotein; Region: Flavoprotein; pfam02441
707186000666	Uncharacterized conserved protein [Function unknown]; Region: COG1284
707186000667	Uncharacterized protein conserved in bacteria (DUF2179); Region: DUF2179; pfam10035
707186000668	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
707186000669	IncA protein; Region: IncA; pfam04156
707186000670	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
707186000671	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
707186000672	solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain; Region: SLC6sbd_Tyt1-Like; cd10336
707186000673	Na2 binding site [ion binding]; other site
707186000674	putative substrate binding site 1 [chemical binding]; other site
707186000675	Na binding site 1 [ion binding]; other site
707186000676	putative substrate binding site 2 [chemical binding]; other site
707186000677	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
707186000678	putative substrate translocation pore; other site
707186000679	cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]; Region: Crp; COG0664
707186000680	effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO...; Region: CAP_ED; cd00038
707186000681	ligand binding site [chemical binding]; other site
707186000682	flexible hinge region; other site
707186000683	acyl carrier protein; Provisional; Region: acpP; PRK00982
707186000684	beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs; Region: BKR_SDR_c; cd05333
707186000685	3-oxoacyl-(acyl-carrier-protein) reductase; Region: 3oxo_ACP_reduc; TIGR01830
707186000686	NAD(P) binding site [chemical binding]; other site
707186000687	homotetramer interface [polypeptide binding]; other site
707186000688	homodimer interface [polypeptide binding]; other site
707186000689	active site
707186000690	(acyl-carrier-protein) S-malonyltransferase [Lipid metabolism]; Region: FabD; COG0331
707186000691	malonyl CoA-acyl carrier protein transacylase; Region: fabD; TIGR00128
707186000692	3-oxoacyl-(acyl-carrier-protein) synthase III; Region: fabH; TIGR00747
707186000693	Ketoacyl-acyl carrier protein synthase III (KASIII) initiates the elongation in type II fatty acid synthase systems. It is found in bacteria and plants. Elongation of fatty acids in the type II systems occurs by Claisen condensation of malonyl-acyl...; Region: KAS_III; cd00830
707186000694	dimer interface [polypeptide binding]; other site
707186000695	active site
707186000696	CoA binding pocket [chemical binding]; other site
707186000697	recombination protein RecR; Region: recR; TIGR00615
707186000698	RecR protein; Region: RecR; pfam02132
707186000699	TOPRIM_recR: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in Escherichia coli RecR.  RecR participates in the RecFOR pathway of homologous recombinational repair in prokaryotes. This pathway provides a...; Region: TOPRIM_recR; cd01025
707186000700	putative active site [active]
707186000701	putative metal-binding site [ion binding]; other site
707186000702	tetramer interface [polypeptide binding]; other site
707186000703	Outer membrane protein/protective antigen OMA87 [Cell envelope biogenesis, outer membrane]; Region: COG4775
707186000704	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
707186000705	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
707186000706	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
707186000707	Surface antigen variable number repeat; Region: Surf_Ag_VNR; pfam07244
707186000708	Surface antigen; Region: Bac_surface_Ag; pfam01103
707186000709	Outer membrane protein [Cell envelope biogenesis, outer membrane]; Region: HlpA; COG2825
707186000710	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Region: lipid_A_lpxD; TIGR01853
707186000711	UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase, LpxD; Region: LpxD; pfam04613
707186000712	UDP-3-O-acyl-glucosamine N-acyltransferase (LpxD): The enzyme catalyzes the transfer of 3-hydroxymyristic acid or 3-hydroxy-arachidic acid, depending on the organism, from the acyl carrier protein (ACP) to UDP-3-O-acyl-glucosamine to produce UDP-2; Region: LbH_LpxD; cd03352
707186000713	trimer interface [polypeptide binding]; other site
707186000714	active site
707186000715	UDP-GlcNAc binding site [chemical binding]; other site
707186000716	lipid binding site [chemical binding]; lipid-binding site
707186000717	pyruvate dehydrogenase E1 component, alpha subunit; Region: PDH_E1_alph_y; TIGR03182
707186000718	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
707186000719	tetramer interface [polypeptide binding]; other site
707186000720	TPP-binding site [chemical binding]; other site
707186000721	heterodimer interface [polypeptide binding]; other site
707186000722	phosphorylation loop region [posttranslational modification]
707186000723	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
707186000724	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
707186000725	alpha subunit interface [polypeptide binding]; other site
707186000726	TPP binding site [chemical binding]; other site
707186000727	heterodimer interface [polypeptide binding]; other site
707186000728	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
707186000729	pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase, long form; Region: PDHac_trf_mito; TIGR01349
707186000730	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
707186000731	E3 interaction surface; other site
707186000732	lipoyl attachment site [posttranslational modification]; other site
707186000733	e3 binding domain; Region: E3_binding; pfam02817
707186000734	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
707186000735	This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of...; Region: GT1_Glycogen_Phosphorylase; cd04300
707186000736	homodimer interface [polypeptide binding]; other site
707186000737	glycogen/starch/alpha-glucan phosphorylases; Region: P_ylase; TIGR02093
707186000738	active site pocket [active]
707186000739	chromosomal replication initiation protein; Provisional; Region: PRK12422
707186000740	DnaA N-terminal domain; Region: DnaA_N; pfam11638
707186000741	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707186000742	Walker A motif; other site
707186000743	ATP binding site [chemical binding]; other site
707186000744	Walker B motif; other site
707186000745	arginine finger; other site
707186000746	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
707186000747	DnaA box-binding interface [nucleotide binding]; other site
707186000748	putative inner membrane protein translocase component YidC; Provisional; Region: PRK01001
707186000749	membrane protein insertase, YidC/Oxa1 family, C-terminal domain; Region: yidC_oxa1_cterm; TIGR03592
707186000750	prolipoprotein diacylglyceryl transferase; Reviewed; Region: PRK00052
707186000751	CAAX protease self-immunity; Region: Abi; pfam02517
707186000752	Nucleoside Triphosphate Pyrophosphohydrolase (EC 3.6.1.8) N-terminal tandem-domain of MazG proteins from Escherichia coli and bacterial homologs; Region: NTP-PPase_MazG_Nterm; cd11528
707186000753	homodimer interface [polypeptide binding]; other site
707186000754	metal binding site [ion binding]; metal-binding site
707186000755	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
707186000756	Domain of unknown function DUF21; Region: DUF21; pfam01595
707186000757	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
707186000758	Transporter associated domain; Region: CorC_HlyC; smart01091
707186000759	Hemolysins and related proteins containing CBS domains [General function prediction only]; Region: TlyC; COG1253
707186000760	Domain of unknown function DUF21; Region: DUF21; pfam01595
707186000761	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
707186000762	Transporter associated domain; Region: CorC_HlyC; smart01091
707186000763	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
707186000764	cysteine desulfurase NifS; Region: FeS_nifS; TIGR03402
707186000765	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
707186000766	catalytic residue [active]
707186000767	Serine/threonine phosphatases, family 2C, catalytic domain; The protein architecture and deduced catalytic mechanism of PP2C phosphatases are similar to the PP1, PP2A, PP2B family of protein Ser/Thr phosphatases, with which PP2C shares no sequence...; Region: PP2Cc; cd00143
707186000768	Protein phosphatase 2C; Region: PP2C; pfam00481
707186000769	active site
707186000770	Uncharacterized conserved protein [Function unknown]; Region: COG5465
707186000771	DNA polymerase III subunit epsilon; Validated; Region: PRK06309
707186000772	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
707186000773	active site
707186000774	catalytic site [active]
707186000775	substrate binding site [chemical binding]; other site
707186000776	Protein of unknown function (DUF3820); Region: DUF3820; cl01411
707186000777	Predicted periplasmic solute-binding protein [General function prediction only]; Region: COG2107
707186000778	nucleosidase; Provisional; Region: PRK05634
707186000779	ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms]; Region: MdlB; COG1132
707186000780	ABC transporter transmembrane region; Region: ABC_membrane; pfam00664
707186000781	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707186000782	Walker A/P-loop; other site
707186000783	ATP binding site [chemical binding]; other site
707186000784	Q-loop/lid; other site
707186000785	ABC transporter signature motif; other site
707186000786	Walker B; other site
707186000787	D-loop; other site
707186000788	H-loop/switch region; other site
707186000789	acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated; Region: PRK05724
707186000790	acetyl-CoA carboxylase carboxyltransferase alpha subunit; Provisional; Region: accA; CHL00198
707186000791	Integration host factor (IHF) and HU are small heterodimeric members of the DNABII protein family that bind and bend DNA, functioning as architectural factors in many cellular processes including transcription, site-specific recombination, and...; Region: HU_IHF; cd00591
707186000792	IHF - DNA interface [nucleotide binding]; other site
707186000793	IHF dimer interface [polypeptide binding]; other site
707186000794	N-acetylmuramoyl-L-alanine amidase [Cell envelope biogenesis, outer membrane]; Region: AmiC; COG0860
707186000795	N-acetylmuramoyl-L-alanine amidase or MurNAc-LAA (also known as peptidoglycan aminohydrolase, NAMLA amidase, NAMLAA, Amidase 3, and peptidoglycan amidase; EC 3.5.1.28) is an autolysin that hydrolyzes the amide bond between N-acetylmuramoyl and L-amino...; Region: MurNAc-LAA; cd02696
707186000796	active site
707186000797	metal binding site [ion binding]; metal-binding site
707186000798	UDP-N-acetylmuramyl-tripeptide synthetase; Region: murE; TIGR01085
707186000799	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
707186000800	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
707186000801	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
707186000802	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
707186000803	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
707186000804	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; pfam00905
707186000805	Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis [Cell envelope biogenesis, outer membrane]; Region: COG0275
707186000806	MraW methylase family; Region: Methyltransf_5; pfam01795
707186000807	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
707186000808	TPR motif; other site
707186000809	binding surface
707186000810	chromosomal replication initiation protein; Reviewed; Region: dnaA; PRK00149
707186000811	DnaA N-terminal domain; Region: DnaA_N; pfam11638
707186000812	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707186000813	Walker A motif; other site
707186000814	ATP binding site [chemical binding]; other site
707186000815	Walker B motif; other site
707186000816	arginine finger; other site
707186000817	C-terminal domain of bacterial DnaA proteins. The DNA-binding C-terminal domain of DnaA contains a helix-turn-helix motif that specifically interacts with the DnaA box, a 9-mer motif that occurs repetitively in the replication origin oriC. Multiple...; Region: Bac_DnaA_C; cd06571
707186000818	DnaA box-binding interface [nucleotide binding]; other site
707186000819	Integral membrane protein CcmA involved in cell shape determination [Cell envelope biogenesis, outer membrane]; Region: CcmA; COG1664
707186000820	Polymer-forming cytoskeletal; Region: Bactofilin; pfam04519
707186000821	Na(+)-translocating NADH-quinone reductase subunit B; Provisional; Region: PRK01024
707186000822	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC [Energy production and conversion]; Region: NqrC; COG2869
707186000823	NADH:ubiquinone oxidoreductase, Na(+)-translocating, C subunit; Region: nqrC; TIGR01938
707186000824	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD [Energy production and conversion]; Region: NqrD; COG1347
707186000825	Na(+)-translocating NADH-quinone reductase subunit E; Provisional; Region: PRK01061
707186000826	Glycine cleavage H-protein. Glycine cleavage H-proteins are part of the glycine cleavage system (GCS) found in bacteria, archea and the mitochondria of eukaryotes. GCS is a multienzyme complex consisting of 4 different components (P-, H-, T- and...; Region: GCS_H; cd06848
707186000827	lipoyl attachment site [posttranslational modification]; other site
707186000828	Chlamydial GcvH-like protein upstream region protein; Region: near_not_gcvH; TIGR03076
707186000829	Phosphatidylserine/phosphatidylglycerophosphate/car diolipin synthases and related enzymes [Lipid metabolism]; Region: Cls; COG1502
707186000830	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
707186000831	putative active site [active]
707186000832	catalytic site [active]
707186000833	Catalytic domain of phospholipase D superfamily proteins; Region: PLDc_SF; cl15239
707186000834	putative active site [active]
707186000835	catalytic site [active]
707186000836	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
707186000837	ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones]; Region: clpA; COG0542
707186000838	Clp amino terminal domain; Region: Clp_N; pfam02861
707186000839	Clp amino terminal domain; Region: Clp_N; pfam02861
707186000840	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707186000841	Walker A motif; other site
707186000842	ATP binding site [chemical binding]; other site
707186000843	Walker B motif; other site
707186000844	arginine finger; other site
707186000845	UvrB/uvrC motif; Region: UVR; pfam02151
707186000846	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707186000847	Walker A motif; other site
707186000848	ATP binding site [chemical binding]; other site
707186000849	Walker B motif; other site
707186000850	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; pfam10431
707186000851	tRNA methyl transferase; Region: tRNA_Me_trans; pfam03054
707186000852	tRNA methyl transferase. This family represents tRNA(5-methylaminomethyl-2-thiouridine)-methyltransferase which is involved in the biosynthesis of the modified nucleoside 5-methylaminomethyl-2-thiouridine present in the wobble position of some tRNAs; Region: tRNA_Me_trans; cd01998
707186000853	Ligand Binding Site [chemical binding]; other site
707186000854	Helix-turn-helix domain; Region: HTH_17; pfam12728
707186000855	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
707186000856	active site
707186000857	phosphorylation site [posttranslational modification]
707186000858	PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This...; Region: PTS_IIA_fru; cd00211
707186000859	active site
707186000860	phosphorylation site [posttranslational modification]
707186000861	Trimeric dUTP diphosphatases; Region: trimeric_dUTPase; cd07557
707186000862	trimer interface [polypeptide binding]; other site
707186000863	active site
707186000864	acetyl-CoA carboxylase subunit beta; Validated; Region: PRK05654
707186000865	malonate decarboxylase subunit beta; Reviewed; Region: PRK07189; cl17682
707186000866	Superoxide dismutase [Inorganic ion transport and metabolism]; Region: SodA; COG0605
707186000867	Iron/manganese superoxide dismutases, alpha-hairpin domain; Region: Sod_Fe_N; pfam00081
707186000868	Iron/manganese superoxide dismutases, C-terminal domain; Region: Sod_Fe_C; pfam02777
707186000869	Phosphomannomutase [Carbohydrate transport and metabolism]; Region: {ManB}; COG1109
707186000870	This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and...; Region: PGM2; cd05799
707186000871	active site
707186000872	substrate binding site [chemical binding]; other site
707186000873	metal binding site [ion binding]; metal-binding site
707186000874	ribonuclease III; Reviewed; Region: rnc; PRK00102
707186000875	RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in...; Region: RIBOc; cd00593
707186000876	dimerization interface [polypeptide binding]; other site
707186000877	active site
707186000878	metal binding site [ion binding]; metal-binding site
707186000879	Double-stranded RNA binding motif. Binding is not sequence specific but is highly specific for double stranded RNA. Found in a variety of proteins including dsRNA dependent protein kinase PKR, RNA helicases, Drosophila staufen protein, E. coli RNase III; Region: DSRM; cd00048
707186000880	dsRNA binding site [nucleotide binding]; other site
707186000881	DNA repair protein RadA; Provisional; Region: PRK11823
707186000882	Sms (bacterial radA) DNA repair protein. This protein is not related to archael radA any more than is to other RecA-like NTPases. Sms has a role in recombination and recombinational repair and is responsible for the stabilization or processing of...; Region: Sms; cd01121
707186000883	Walker A motif/ATP binding site; other site
707186000884	ATP binding site [chemical binding]; other site
707186000885	Walker B motif; other site
707186000886	Subunit ChlI of Mg-chelatase; Region: ChlI; pfam13541
707186000887	porphobilinogen deaminase; Provisional; Region: PRK01066
707186000888	Porphobilinogen deaminase, dipyromethane cofactor binding domain; Region: Porphobil_deam; pfam01379
707186000889	serine/threonine-protein kinase; Reviewed; Region: pknD; PRK13184
707186000890	Catalytic domain of Protein Kinases; Region: PKc; cd00180
707186000891	active site
707186000892	ATP binding site [chemical binding]; other site
707186000893	substrate binding site [chemical binding]; other site
707186000894	activation loop (A-loop); other site
707186000895	valyl-tRNA synthetase; Reviewed; Region: valS; PRK05729
707186000896	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
707186000897	HIGH motif; other site
707186000898	Leucyl-tRNA synthetase, Domain 2; Region: tRNA-synt_1_2; pfam13603
707186000899	catalytic core domain of valyl-tRNA synthetases; Region: ValRS_core; cd00817
707186000900	active site
707186000901	KMSKS motif; other site
707186000902	Anticodon-binding domain of valyl tRNA synthetases; Region: Anticodon_Ia_Val; cd07962
707186000903	tRNA binding surface [nucleotide binding]; other site
707186000904	anticodon binding site; other site
707186000905	Valyl tRNA synthetase tRNA binding arm; Region: Val_tRNA-synt_C; pfam10458
707186000906	V-type ATP synthase subunit K; Provisional; Region: PRK09621
707186000907	ATP synthase subunit C; Region: ATP-synt_C; pfam00137
707186000908	V-type ATP synthase subunit I; Validated; Region: PRK05771
707186000909	Protein of unknown function (DUF1319); Region: DUF1319; pfam07028
707186000910	V-type ATP synthase subunit D; Provisional; Region: PRK02195
707186000911	V-type ATP synthase subunit B; Provisional; Region: PRK02118
707186000912	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
707186000913	V/A-type ATP synthase (non-catalytic) subunit B. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction. The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_B; cd01135
707186000914	Walker A motif homologous position; other site
707186000915	Walker B motif; other site
707186000916	V-type ATP synthase subunit A; Provisional; Region: PRK04192
707186000917	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
707186000918	V/A-type ATP synthase catalytic subunit A. These ATPases couple ATP hydrolysis to the build up of a H+ gradient, but V-type ATPases do not catalyze the reverse reaction.  The Vacuolar (V-type) ATPase is found in the membranes of vacuoles, the golgi...; Region: V_A-ATPase_A; cd01134
707186000919	Walker A motif/ATP binding site; other site
707186000920	Walker B motif; other site
707186000921	ATP synthase alpha/beta chain, C terminal domain; Region: ATP-synt_ab_C; pfam00306
707186000922	Protein of unknown function (DUF2764); Region: DUF2764; pfam10962
707186000923	V-type ATP synthase subunit E; Provisional; Region: PRK01005
707186000924	V-type ATP synthase subunit E; Provisional; Region: PRK01558
707186000925	transaldolase-like protein; Provisional; Region: PTZ00411
707186000926	Transaldolases including both TalA and TalB; Region: Transaldolase_TalAB; cd00957
707186000927	active site
707186000928	dimer interface [polypeptide binding]; other site
707186000929	catalytic residue [active]
707186000930	RNA polymerase Rpb1, domain 1; Region: RNA_pol_Rpb1_1; pfam04997
707186000931	DNA-directed RNA polymerase, beta' subunit, predominant form; Region: rpoC_TIGR; TIGR02386
707186000932	RNA polymerase I subunit A N-terminus; Region: RPOLA_N; smart00663
707186000933	RNA polymerase Rpb1, domain 3; Region: RNA_pol_Rpb1_3; pfam04983
707186000934	RNA polymerase Rpb1, domain 4; Region: RNA_pol_Rpb1_4; pfam05000
707186000935	Largest subunit of RNA polymerase (RNAP), C-terminal domain; Region: RNAP_largest_subunit_C; cl11429
707186000936	Rpb1 - Rpb6 interaction site [polypeptide binding]; other site
707186000937	Largest subunit (beta') of Bacterial DNA-dependent RNA polymerase (RNAP), C-terminal domain; Region: RNAP_beta'_C; cd02655
707186000938	DNA binding site [nucleotide binding]
707186000939	Rpb1 (beta') - Rpb2 (beta) interaction site [polypeptide binding]; other site
707186000940	RNA polymerase beta subunit; Region: RNA_pol_Rpb2_1; pfam04563
707186000941	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cl17585
707186000942	RNA polymerase Rpb2, domain 2; Region: RNA_pol_Rpb2_2; pfam04561
707186000943	DNA-directed RNA polymerase, beta subunit; Region: rpoB; TIGR02013
707186000944	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
707186000945	RNA polymerase Rpb2, domain 6; Region: RNA_pol_Rpb2_6; pfam00562
707186000946	RPB12 interaction site [polypeptide binding]; other site
707186000947	RNA polymerase beta subunit. RNA polymerases catalyse the DNA dependent polymerization of RNA. Prokaryotes contain a single RNA polymerase compared to three in eukaryotes (not including mitochondrial. and chloroplast polymerases). Each RNA polymerase...; Region: RNA_pol_B_RPB2; cd00653
707186000948	RPB3 interaction site [polypeptide binding]; other site
707186000949	RPB1 interaction site [polypeptide binding]; other site
707186000950	RPB11 interaction site [polypeptide binding]; other site
707186000951	RPB10 interaction site [polypeptide binding]; other site
707186000952	Ribosomal protein L7/L12. Ribosomal protein L7/L12 refers to the large ribosomal subunit proteins L7 and L12, which are identical except that L7 is acetylated at the N terminus. It is a component of the L7/L12 stalk, which is located at the surface of...; Region: Ribosomal_L7_L12; cd00387
707186000953	L11 interface [polypeptide binding]; other site
707186000954	putative EF-Tu interaction site [polypeptide binding]; other site
707186000955	putative EF-G interaction site [polypeptide binding]; other site
707186000956	Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein...; Region: Ribosomal_L10; cd05797
707186000957	23S rRNA interface [nucleotide binding]; other site
707186000958	Interface with L7/L12 ribosomal proteins [polypeptide binding]; other site
707186000959	Ribosomal protein L1.  The L1 protein, located near the E-site of the ribosome, forms part of the L1 stalk along with 23S rRNA.  In bacteria and archaea, L1 functions both as a ribosomal protein that binds rRNA, and as a translation repressor that binds...; Region: Ribosomal_L1; cd00403
707186000960	mRNA/rRNA interface [nucleotide binding]; other site
707186000961	50S ribosomal protein L11; Validated; Region: rplK; PRK00140
707186000962	Ribosomal protein L11. Ribosomal protein L11, together with proteins L10 and L7/L12, and 23S rRNA, form the L7/L12 stalk on the surface of the large subunit of the ribosome. The homologous eukaryotic cytoplasmic protein is also called 60S ribosomal...; Region: Ribosomal_L11; cd00349
707186000963	putative thiostrepton binding site; other site
707186000964	23S rRNA interface [nucleotide binding]; other site
707186000965	L7/L12 interface [polypeptide binding]; other site
707186000966	L25 interface [polypeptide binding]; other site
707186000967	Bacterial N-Utilization Substance G (NusG) N-terminal (NGN) domain, subgroup 1; Region: NGN_Bact_1; cd09891
707186000968	transcription termination/antitermination factor NusG; Region: nusG; TIGR00922
707186000969	putative homodimer interface [polypeptide binding]; other site
707186000970	NusG contains an NGN domain at its N-terminus and KOW motif at its C-terminus; Region: KOW_NusG; cd06091
707186000971	heterodimer interface [polypeptide binding]; other site
707186000972	homodimer interface [polypeptide binding]; other site
707186000973	Preprotein translocase subunit SecE [Intracellular trafficking and secretion]; Region: SecE; COG0690
707186000974	elongation factor Tu; Reviewed; Region: PRK12735
707186000975	Elongation Factor Tu (EF-Tu) GTP-binding proteins; Region: EF_Tu; cd01884
707186000976	G1 box; other site
707186000977	GEF interaction site [polypeptide binding]; other site
707186000978	GTP/Mg2+ binding site [chemical binding]; other site
707186000979	Switch I region; other site
707186000980	G2 box; other site
707186000981	G3 box; other site
707186000982	Switch II region; other site
707186000983	G4 box; other site
707186000984	G5 box; other site
707186000985	EFTU_II: Elongation factor Tu domain II. Elongation factors Tu (EF-Tu) are three-domain GTPases with an essential function in the elongation phase of mRNA translation. The GTPase center of EF-Tu is in the N-terminal domain (domain I), also known as the...; Region: EFTU_II; cd03697
707186000986	Domain III of elongation factor (EF) Tu. Ef-Tu consists of three structural domains, designated I, II and III. Domain III adopts a beta barrel structure. Domain III is involved in binding to both charged tRNA and binding to elongation factor Ts (EF-Ts); Region: EFTU_III; cd03707
707186000987	Antibiotic Binding Site [chemical binding]; other site
707186000988	S1_IF1: Translation Initiation Factor IF1, S1-like RNA-binding domain. IF1 contains an S1-like RNA-binding domain, which is found in a wide variety of RNA-associated proteins. Translation initiation includes a number of interrelated steps preceding the...; Region: S1_IF1; cd04451
707186000989	rRNA binding site [nucleotide binding]; other site
707186000990	predicted 30S ribosome binding site; other site
707186000991	Cysteine desulfurase SufE subunit [Posttranslational modification, protein turnover, chaperones]; Region: sufE; COG2166
707186000992	Protein of unknown function (DUF687); Region: DUF687; pfam05095
707186000993	Phosphoribosylanthranilate isomerase (PRAI) catalyzes the fourth step of the tryptophan biosynthesis, the conversion of N-(5'- phosphoribosyl)-anthranilate (PRA) to 1-(o-carboxyphenylamino)- 1-deoxyribulose 5-phosphate (CdRP). Most PRAIs are...; Region: PRAI; cd00405
707186000994	active site
707186000995	Triosephosphate isomerase (TIM) is a glycolytic enzyme that catalyzes the interconversion of dihydroxyacetone phosphate and D-glyceraldehyde-3-phosphate. The reaction is very efficient and requires neither cofactors nor metal ions. TIM, usually...; Region: TIM; cd00311
707186000996	triosephosphate isomerase; Provisional; Region: PRK14565
707186000997	substrate binding site [chemical binding]; other site
707186000998	dimer interface [polypeptide binding]; other site
707186000999	catalytic triad [active]
707186001000	Exonuclease VII, large subunit [DNA replication, recombination, and repair]; Region: XseA; COG1570
707186001001	ExoVII_LU_OBF: A subfamily of OB folds corresponding to the N-terminal OB-fold domain of Escherichia coli exodeoxyribonuclease VII (ExoVII) large subunit. E. coli ExoVII is composed of two non-identical subunits. E. coli ExoVII is a...; Region: ExoVII_LU_OBF; cd04489
707186001002	generic binding surface II; other site
707186001003	generic binding surface I; other site
707186001004	exodeoxyribonuclease VII small subunit; Provisional; Region: PRK00977
707186001005	Deoxyxylulose-5-phosphate synthase [Coenzyme metabolism / Lipid metabolism]; Region: Dxs; COG1154
707186001006	1-deoxy-D-xylulose-5-phosphate synthase; Region: DXP_synthase_N; pfam13292
707186001007	TPP-binding site [chemical binding]; other site
707186001008	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
707186001009	PYR/PP interface [polypeptide binding]; other site
707186001010	dimer interface [polypeptide binding]; other site
707186001011	TPP binding site [chemical binding]; other site
707186001012	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
707186001013	Pyruvate kinase (PK):  Large allosteric enzyme that regulates glycolysis through binding of the substrate, phosphoenolpyruvate, and one or more allosteric effectors. Like other allosteric enzymes, PK has a high substrate affinity R state and a low...; Region: Pyruvate_Kinase; cl17342
707186001014	pyruvate kinase; Region: pyruv_kin; TIGR01064
707186001015	domain interfaces; other site
707186001016	active site
707186001017	excinuclease ABC subunit A; Provisional; Region: PRK00635
707186001018	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
707186001019	ATP-binding cassette domain I of the excision repair protein UvrA; Region: ABC_UvrA_I; cd03270
707186001020	ATP-binding cassette domain II of the excision repair protein UvrA; Region: ABC_UvrA_II; cd03271
707186001021	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707186001022	Walker A/P-loop; other site
707186001023	ATP binding site [chemical binding]; other site
707186001024	Q-loop/lid; other site
707186001025	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707186001026	ABC transporter signature motif; other site
707186001027	Walker B; other site
707186001028	D-loop; other site
707186001029	H-loop/switch region; other site
707186001030	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707186001031	Walker A/P-loop; other site
707186001032	ATP binding site [chemical binding]; other site
707186001033	Q-loop/lid; other site
707186001034	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707186001035	Q-loop/lid; other site
707186001036	ABC transporter signature motif; other site
707186001037	Walker B; other site
707186001038	D-loop; other site
707186001039	H-loop/switch region; other site
707186001040	DNA polymerase III subunits gamma and tau; Validated; Region: PRK06305
707186001041	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707186001042	Walker A motif; other site
707186001043	ATP binding site [chemical binding]; other site
707186001044	Walker B motif; other site
707186001045	arginine finger; other site
707186001046	hypothetical protein; Validated; Region: PRK00153
707186001047	phosphoenolpyruvate-protein phosphotransferase; Region: PTS_I_fam; TIGR01417
707186001048	PEP-utilising enzyme, N-terminal; Region: PEP-utilisers_N; pfam05524
707186001049	PEP-utilising enzyme, mobile domain; Region: PEP-utilizers; pfam00391
707186001050	PEP-utilising enzyme, TIM barrel domain; Region: PEP-utilizers_C; pfam02896
707186001051	Histidine-containing phosphocarrier protein (HPr)-like proteins. HPr is a central component of the bacterial phosphoenolpyruvate sugar phosphotransferase system (PTS). The PTS catalyses the phosphorylation of sugar substrates during their translocation...; Region: PTS-HPr_like; cd00367
707186001052	dimerization domain swap beta strand [polypeptide binding]; other site
707186001053	regulatory protein interface [polypeptide binding]; other site
707186001054	active site
707186001055	regulatory phosphorylation site [posttranslational modification]; other site
707186001056	Predicted membrane metal-binding protein [General function prediction only]; Region: ComEC; COG0658
707186001057	Competence protein; Region: Competence; pfam03772
707186001058	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion]; Region: AcoA; COG1071
707186001059	Thiamine pyrophosphate (TPP) family, E1 of PDC_ADC_BCADC subfamily, TPP-binding module; composed of proteins similar to the E1 components of the human pyruvate dehydrogenase complex (PDC), the acetoin dehydrogenase complex (ADC) and the branched chain...; Region: TPP_E1_PDC_ADC_BCADC; cd02000
707186001060	tetramer interface [polypeptide binding]; other site
707186001061	TPP-binding site [chemical binding]; other site
707186001062	heterodimer interface [polypeptide binding]; other site
707186001063	phosphorylation loop region [posttranslational modification]
707186001064	Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion]; Region: AcoB; COG0022
707186001065	Pyrimidine (PYR) binding domain of the beta subunits of the E1 components of human pyruvate dehydrogenase complex (E1- PDHc) and related proteins; Region: TPP_PYR_E1-PDHc-beta_like; cd07036
707186001066	alpha subunit interface [polypeptide binding]; other site
707186001067	TPP binding site [chemical binding]; other site
707186001068	heterodimer interface [polypeptide binding]; other site
707186001069	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
707186001070	chaperone protein DnaJ; Provisional; Region: PRK14284
707186001071	DnaJ domain or J-domain.  DnaJ/Hsp40 (heat shock protein 40) proteins are highly conserved and play crucial roles in protein translation, folding, unfolding, translocation, and degradation. They act primarily by stimulating the ATPase activity of Hsp70s; Region: DnaJ; cd06257
707186001072	HSP70 interaction site [polypeptide binding]; other site
707186001073	Zinc finger domain of DnaJ and HSP40; Region: DnaJ_zf; cd10719
707186001074	Zn binding sites [ion binding]; other site
707186001075	C-terminal substrate binding domain of DnaJ and HSP40; Region: DnaJ_C; cd10747
707186001076	dimer interface [polypeptide binding]; other site
707186001077	30S ribosomal protein S21; Reviewed; Region: rpsU; PRK00270
707186001078	Inactive homolog of metal-dependent proteases, putative molecular chaperone [Posttranslational modification, protein turnover, chaperones]; Region: COG1214
707186001079	Glycoprotease family; Region: Peptidase_M22; pfam00814
707186001080	ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones]; Region: Lon; COG0466
707186001081	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707186001082	Walker A motif; other site
707186001083	ATP binding site [chemical binding]; other site
707186001084	Walker B motif; other site
707186001085	arginine finger; other site
707186001086	Lon protease (S16) C-terminal proteolytic domain; Region: Lon_C; pfam05362
707186001087	ribonuclease Z; Region: RNase_Z; TIGR02651
707186001088	site-specific tyrosine recombinase XerC; Reviewed; Region: xerC; PRK00236
707186001089	XerD and XerC integrases, DNA breaking-rejoining enzymes, N- and C-terminal domains. XerD-like integrases are involved in the site-specific integration and excision of lysogenic bacteriophage genomes, transposition of conjugative transposons, termination...; Region: INT_XerDC; cd00798
707186001090	active site
707186001091	Int/Topo IB signature motif; other site
707186001092	ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only]; Region: Uup; COG0488
707186001093	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
707186001094	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
707186001095	ABC transporter; Region: ABC_tran_2; pfam12848
707186001096	ATP-binding cassette domain of elongation factor 3, subfamily F; Region: ABCF_EF-3; cd03221
707186001097	Maf-like protein; Region: Maf; pfam02545
707186001098	Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or...; Region: Maf; cd00555
707186001099	active site
707186001100	dimer interface [polypeptide binding]; other site
707186001101	FOG: HEAT repeat [Energy production and conversion]; Region: COG1413
707186001102	Preprotein translocase subunit SecG [Intracellular trafficking and secretion]; Region: SecG; COG1314
707186001103	Polypeptide or peptide deformylase; a family of metalloenzymes that catalyzes the removal of the N-terminal formyl group in a growing polypeptide chain following translation initiation during protein synthesis in prokaryotes. These enzymes utilize Fe(II)...; Region: Pep_deformylase; cd00487
707186001104	active site
707186001105	catalytic residues [active]
707186001106	metal binding site [ion binding]; metal-binding site
707186001107	16S ribosomal RNA methyltransferase KsgA/Dim1 family protein; Reviewed; Region: ksgA; PRK00274
707186001108	dimethyladenosine transferase; Region: ksgA; TIGR00755
707186001109	Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones]; Region: COG1331
707186001110	TRX domain, SSP411 protein family; members of this family are highly conserved proteins present in eukaryotes, bacteria and archaea, about 600-800 amino acids in length, which contain a TRX domain with a redox active CXXC motif. The human/rat protein; Region: SSP411; cd02955
707186001111	catalytic residues [active]
707186001112	Uncharacterized conserved protein [General function prediction only]; Region: BioY; COG1268
707186001113	dihydrodipicolinate synthase; Region: dapA; TIGR00674
707186001114	Dihydrodipicolinate synthase family; Region: DHDPS-like; cd00408
707186001115	inhibitor site; inhibition site
707186001116	active site
707186001117	dimer interface [polypeptide binding]; other site
707186001118	catalytic residue [active]
707186001119	aspartate kinase; Provisional; Region: PRK05925
707186001120	AAK_AK-HSDH-like: Amino Acid Kinase Superfamily (AAK), AK-HSDH-like; this family includes the N-terminal catalytic domain of aspartokinase (AK) of the bifunctional enzyme AK- homoserine dehydrogenase (HSDH). These aspartokinases are found in such...; Region: AAK_AK-HSDH-like; cd04243
707186001121	putative catalytic residues [active]
707186001122	nucleotide binding site [chemical binding]; other site
707186001123	aspartate binding site [chemical binding]; other site
707186001124	aspartate-semialdehyde dehydrogenase; Reviewed; Region: PRK08664
707186001125	Semialdehyde dehydrogenase, NAD binding domain; Region: Semialdhyde_dh; smart00859
707186001126	Dihydrodipicolinate reductase [Amino acid transport and metabolism]; Region: DapB; COG0289
707186001127	Dihydrodipicolinate reductase, N-terminus; Region: DapB_N; pfam01113
707186001128	Dihydrodipicolinate reductase, C-terminus; Region: DapB_C; pfam05173
707186001129	5-enolpyruvylshikimate-3-phosphate synthase [Amino acid transport and metabolism]; Region: AroA; COG0128
707186001130	EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form...; Region: EPSP_synthase; cd01556
707186001131	hinge; other site
707186001132	active site
707186001133	shikimate kinase; Provisional; Region: PRK00625
707186001134	Shikimate kinase (SK) is the fifth enzyme in the shikimate pathway, a seven-step biosynthetic pathway which converts erythrose-4-phosphate to chorismic acid, found in bacteria, fungi and plants. Chorismic acid is a important intermediate in the synthesis...; Region: SK; cd00464
707186001135	ADP binding site [chemical binding]; other site
707186001136	magnesium binding site [ion binding]; other site
707186001137	putative shikimate binding site; other site
707186001138	Chorismate synthase [Amino acid transport and metabolism]; Region: AroC; COG0082
707186001139	Chorismase synthase, the enzyme catalyzing the final step of the shikimate pathway; Region: Chorismate_synthase; cd07304
707186001140	Tetramer interface [polypeptide binding]; other site
707186001141	active site
707186001142	FMN-binding site [chemical binding]; other site
707186001143	Dehydroquinate synthase (DHQS) catalyzes the conversion of DAHP to DHQ in shikimate pathway for aromatic compounds synthesis; Region: DHQS; cd08195
707186001144	active site
707186001145	dimer interface [polypeptide binding]; other site
707186001146	metal binding site [ion binding]; metal-binding site
707186001147	bifunctional 3-dehydroquinate dehydratase/shikimate dehydrogenase protein; Reviewed; Region: aroDE; PRK09310
707186001148	Type I 3-dehydroquinase, (3-dehydroquinate dehydratase or DHQase); Region: DHQase_I; cd00502
707186001149	active site
707186001150	catalytic residue [active]
707186001151	dimer interface [polypeptide binding]; other site
707186001152	Shikimate dehydrogenase substrate binding domain; Region: Shikimate_dh_N; pfam08501
707186001153	NAD(P) binding domain of Shikimate dehydrogenase; Region: NAD_bind_Shikimate_DH; cd01065
707186001154	shikimate binding site; other site
707186001155	NAD(P) binding site [chemical binding]; other site
707186001156	Protein of unknown function (DUF2608); Region: DUF2608; pfam11019
707186001157	Carbohydrate-selective porin, OprB family; Region: OprB; pfam04966
707186001158	Pyruvoyl-dependent arginine decarboxylase (PvlArgDC) [Amino acid    transport and metabolism]; Region: COG1945
707186001159	transporter, basic amino acid/polyamine antiporter (APA) family; Region: 2A0302; TIGR00905
707186001160	Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism]; Region: DadA; COG0665
707186001161	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; cl17500
707186001162	malate dehydrogenase; Provisional; Region: PRK05442
707186001163	Chloroplast-like malate dehydrogenases; Region: MDH_choloroplast_like; cd01338
707186001164	NAD(P) binding site [chemical binding]; other site
707186001165	dimer interface [polypeptide binding]; other site
707186001166	malate binding site [chemical binding]; other site
707186001167	glucose-6-phosphate isomerase; Provisional; Region: pgi; PRK14095
707186001168	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the first SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_1; cd05015
707186001169	active site
707186001170	dimer interface [polypeptide binding]; other site
707186001171	Phosphoglucose isomerase (PGI) contains two SIS (Sugar ISomerase) domains. This classification is based on the alignment of the second SIS domain. PGI is a multifunctional enzyme which as an intracellular dimer catalyzes the reversible isomerization of...; Region: SIS_PGI_2; cd05016
707186001172	dimer interface [polypeptide binding]; other site
707186001173	active site
707186001174	GTPases [General function prediction only]; Region: HflX; COG2262
707186001175	GTP-binding GTPase N-terminal; Region: GTP-bdg_N; pfam13167
707186001176	HflX GTPase family; Region: HflX; cd01878
707186001177	G1 box; other site
707186001178	GTP/Mg2+ binding site [chemical binding]; other site
707186001179	Switch I region; other site
707186001180	G2 box; other site
707186001181	G3 box; other site
707186001182	Switch II region; other site
707186001183	G4 box; other site
707186001184	G5 box; other site
707186001185	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
707186001186	putative hydrolase; Provisional; Region: PRK02113
707186001187	Bacterial periplasmic substrate-binding proteins; Region: PBPb; smart00062
707186001188	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
707186001189	substrate binding pocket [chemical binding]; other site
707186001190	membrane-bound complex binding site; other site
707186001191	hinge residues; other site
707186001192	3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase [Amino acid transport and metabolism]; Region: AroA; COG2876
707186001193	phospho-2-dehydro-3-deoxyheptonate aldolase; Region: DAHP_synth_Bsub; TIGR01361
707186001194	FOG: HEAT repeat [Energy production and conversion]; Region: COG1413
707186001195	Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a...; Region: PKCI_related; cd01276
707186001196	nucleotide binding site/active site [active]
707186001197	Uncharacterized conserved protein related to MYG1 family [Function unknown]; Region: COG4286
707186001198	Predicted Rossmann fold nucleotide-binding protein [General function prediction only]; Region: COG1611
707186001199	hypothetical protein; Validated; Region: PRK00647
707186001200	Protein of unknown function (DUF1207); Region: DUF1207; pfam06727
707186001201	LL-diaminopimelate aminotransferase; Region: DAPAT_plant; TIGR03542
707186001202	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
707186001203	pyridoxal 5'-phosphate binding site [chemical binding]; other site
707186001204	homodimer interface [polypeptide binding]; other site
707186001205	catalytic residue [active]
707186001206	ABC transporter substrate binding protein; Region: ABC_sub_bind; pfam04392
707186001207	prolyl-tRNA synthetase; Provisional; Region: PRK09194
707186001208	Prolyl-tRNA synthetase (ProRS) class II core catalytic domain. ProRS is a homodimer. It is responsible for the attachment of proline to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ProRS_core_prok; cd00779
707186001209	dimer interface [polypeptide binding]; other site
707186001210	motif 1; other site
707186001211	active site
707186001212	motif 2; other site
707186001213	INS is an amino acid-editing domain inserted (INS) into the bacterial class II prolyl-tRNA synthetase (ProRS) however, this CD is not exclusively bacterial. It is also found at the N-terminus of the eukaryotic/archaea-like ProRS's of yeasts and...; Region: ProRS-INS; cd04334
707186001214	putative deacylase active site [active]
707186001215	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
707186001216	active site
707186001217	motif 3; other site
707186001218	ProRS Prolyl-anticodon binding domain, short version found predominantly in bacteria. ProRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding; Region: ProRS_anticodon_short; cd00861
707186001219	anticodon binding site; other site
707186001220	Transcriptional regulator of heat shock gene [Transcription]; Region: HrcA; COG1420
707186001221	GrpE; Region: GrpE; pfam01025
707186001222	GrpE is the adenine nucleotide exchange factor of DnaK (Hsp70)-type ATPases. The GrpE dimer binds to the ATPase domain of Hsp70 catalyzing the dissociation of ADP, which enables rebinding of ATP, one step in the Hsp70 reaction cycle in protein folding; Region: GrpE; cd00446
707186001223	dimer interface [polypeptide binding]; other site
707186001224	hsp70 (ATPase domain) interactions [polypeptide binding]; other site
707186001225	molecular chaperone DnaK; Provisional; Region: dnaK; PRK00290
707186001226	Nucleotide-binding domain of human HSPA9 and similar proteins; Region: HSPA9-Ssq1-like_NBD; cd10234
707186001227	nucleotide binding site [chemical binding]; other site
707186001228	NEF interaction site [polypeptide binding]; other site
707186001229	SBD interface [polypeptide binding]; other site
707186001230	Archaeal/vacuolar-type H+-ATPase subunit H [Energy production and conversion]; Region: NtpF; COG2811
707186001231	Exoribonuclease R [Transcription]; Region: VacB; COG0557
707186001232	Ribonuclease B OB domain; Region: OB_RNB; pfam08206
707186001233	RNB domain; Region: RNB; pfam00773
707186001234	Zn-ribbon protein, possibly nucleic acid-binding [General function prediction only]; Region: COG1579
707186001235	Putative zinc ribbon domain; Region: DUF164; pfam02591
707186001236	KpsF/GutQ family protein; Region: kpsF; TIGR00393
707186001237	KpsF-like protein. KpsF is an arabinose-5-phosphate isomerase which contains SIS (Sugar ISomerase) domains. SIS domains are found in many phosphosugar isomerases and phosphosugar binding proteins. KpsF catalyzes the reversible reaction of ribulose...; Region: SIS_Kpsf; cd05014
707186001238	putative active site [active]
707186001239	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with KpsF/GutQ domains in the API [A5P (D-arabinose 5-phosphate) isomerase] protein.  These APIs catalyze the conversion of the pentose pathway...; Region: CBS_pair_KpsF_GutQ_assoc; cd04604
707186001240	branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed; Region: PRK11856
707186001241	Lipoyl domain of the dihydrolipoyl acyltransferase component (E2) of 2-oxo acid dehydrogenases. 2-oxo acid dehydrogenase multienzyme complexes, like pyruvate dehydrogenase (PDH), 2-oxoglutarate dehydrogenase (OGDH) and branched-chain 2-oxo acid...; Region: lipoyl_domain; cd06849
707186001242	E3 interaction surface; other site
707186001243	lipoyl attachment site [posttranslational modification]; other site
707186001244	e3 binding domain; Region: E3_binding; pfam02817
707186001245	2-oxoacid dehydrogenases acyltransferase (catalytic domain); Region: 2-oxoacid_dh; pfam00198
707186001246	Sodium:dicarboxylate symporter family; Region: SDF; pfam00375
707186001247	Na+/H+-dicarboxylate symporters [Energy production and conversion]; Region: GltP; COG1301
707186001248	tetraacyldisaccharide 4'-kinase; Reviewed; Region: lpxK; PRK00652
707186001249	tetraacyldisaccharide 4'-kinase; Region: lpxK; TIGR00682
707186001250	rRNA methylases [Translation, ribosomal structure and biogenesis]; Region: SpoU; COG0566
707186001251	RNA 2'-O ribose methyltransferase substrate binding; Region: SpoU_sub_bind; pfam08032
707186001252	SpoU rRNA Methylase family; Region: SpoU_methylase; pfam00588
707186001253	Predicted SAM-dependent methyltransferases [General function prediction only]; Region: COG1092
707186001254	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
707186001255	S-adenosylmethionine binding site [chemical binding]; other site
707186001256	riboflavin synthase subunit alpha; Provisional; Region: PRK13020
707186001257	Lumazine binding domain; Region: Lum_binding; pfam00677
707186001258	Lumazine binding domain; Region: Lum_binding; pfam00677
707186001259	Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains [Transcription]; Region: COG1327
707186001260	ATP cone domain; Region: ATP-cone; pfam03477
707186001261	DnaK suppressor protein [Signal transduction mechanisms]; Region: DksA; COG1734
707186001262	Lipoprotein signal peptidase [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion]; Region: LspA; COG0597
707186001263	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
707186001264	amino acid carrier protein; Region: agcS; TIGR00835
707186001265	poly(A) polymerase; Region: pcnB; TIGR01942
707186001266	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
707186001267	active site
707186001268	NTP binding site [chemical binding]; other site
707186001269	metal binding triad [ion binding]; metal-binding site
707186001270	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
707186001271	lipid-A-disaccharide synthase; Reviewed; Region: lpxB; PRK01021
707186001272	Lipid A Biosynthesis N-terminal domain; Region: LAB_N; pfam07578
707186001273	Predicted membrane protein [Function unknown]; Region: COG3952
707186001274	ipid-A-disaccharide synthase; Provisional; Region: PRK14089
707186001275	Chlamydial polymorphic outer membrane protein repeat; Region: POMP_repeat; TIGR01376
707186001276	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707186001277	Autotransporter beta-domain; Region: Autotransporter; pfam03797
707186001278	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707186001279	Autotransporter beta-domain; Region: Autotransporter; pfam03797
707186001280	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707186001281	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707186001282	Autotransporter beta-domain; Region: Autotransporter; pfam03797
707186001283	Helical backbone metal receptor (TroA-like domain). These proteins have been shown to function in the ABC transport of ferric siderophores and metal ions such as Mn2+, Fe3+, Cu2+ and/or Zn2+.  Their ligand binding site is formed in the interface between...; Region: TroA-like; cl00262
707186001284	Periplasmic solute binding protein family; Region: SBP_bac_9; pfam01297
707186001285	intersubunit interface [polypeptide binding]; other site
707186001286	ATP-binding cassette transporter nucleotide-binding domain; Region: ABC_ATPase; cl17201
707186001287	ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms]; Region: SalX; COG1136
707186001288	Walker A/P-loop; other site
707186001289	ATP binding site [chemical binding]; other site
707186001290	Q-loop/lid; other site
707186001291	ABC transporter signature motif; other site
707186001292	Walker B; other site
707186001293	D-loop; other site
707186001294	H-loop/switch region; other site
707186001295	ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism]; Region: ZnuB; COG1108
707186001296	Transmembrane subunit (TM), of Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters involved in the uptake of siderophores, heme, vitamin B12, or the divalent cations Mg2+ and Zn2+. PBP-dependent ABC transporters consist of...; Region: TM_ABC_iron-siderophores_like; cd06550
707186001297	ABC-ATPase subunit  interface; other site
707186001298	dimer interface [polypeptide binding]; other site
707186001299	putative PBP binding regions; other site
707186001300	GTPase CgtA; Reviewed; Region: obgE; PRK12299
707186001301	GTP1/OBG; Region: GTP1_OBG; pfam01018
707186001302	Obg GTPase; Region: Obg; cd01898
707186001303	G1 box; other site
707186001304	GTP/Mg2+ binding site [chemical binding]; other site
707186001305	Switch I region; other site
707186001306	G2 box; other site
707186001307	G3 box; other site
707186001308	Switch II region; other site
707186001309	G4 box; other site
707186001310	G5 box; other site
707186001311	50S ribosomal protein L27; Validated; Region: rpmA; PRK05435
707186001312	Ribosomal protein L21 [Translation, ribosomal structure and biogenesis]; Region: RplU; COG0261
707186001313	Uncharacterized conserved protein [Function unknown]; Region: COG2928
707186001314	Chlam_Verruc_Plancto small basic protein; Region: Chlam_Ver_rRNA; TIGR04137
707186001315	Predicted metal-dependent hydrolase [General function prediction only]; Region: COG0319
707186001316	FOG: CBS domain [General function prediction only]; Region: COG0517
707186001317	This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in...; Region: CBS_pair_CorC_HlyC_assoc; cd04590
707186001318	Transporter associated domain; Region: CorC_HlyC; smart01091
707186001319	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
707186001320	anti sigma factor interaction site; other site
707186001321	regulatory phosphorylation site [posttranslational modification]; other site
707186001322	Protein of unknown function (DUF3604); Region: DUF3604; pfam12228
707186001323	hypothetical protein; Provisional; Region: PRK05926
707186001324	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
707186001325	FeS/SAM binding site; other site
707186001326	Predicted periplasmic solute-binding protein [General function prediction only]; Region: COG1427
707186001327	Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism]; Region: UbiE; COG2226
707186001328	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
707186001329	S-adenosylmethionine binding site [chemical binding]; other site
707186001330	The Ntn hydrolases (N-terminal nucleophile) are a diverse superfamily of of enzymes that are activated autocatalytically via an N-terminally lcated nucleophilic amino acid.  N-terminal nucleophile (NTN-) hydrolase superfamily, which contains a...; Region: Ntn_hydrolase; cl00467
707186001331	Uncharacterized protein family (UPF0158); Region: UPF0158; pfam03682
707186001332	diaminopimelate epimerase; Region: DapF; TIGR00652
707186001333	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
707186001334	Diaminopimelate epimerase; Region: DAP_epimerase; pfam01678
707186001335	ATP-dependent Clp protease proteolytic subunit; Reviewed; Region: PRK12553
707186001336	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
707186001337	oligomer interface [polypeptide binding]; other site
707186001338	active site residues [active]
707186001339	serine hydroxymethyltransferase; Provisional; Region: PRK13580
707186001340	Serine-glycine hydroxymethyltransferase (SHMT). This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). SHMT carries out interconversion of serine and glycine; it catalyzes the transfer of hydroxymethyl...; Region: SHMT; cd00378
707186001341	dimer interface [polypeptide binding]; other site
707186001342	active site
707186001343	glycine-pyridoxal phosphate binding site [chemical binding]; other site
707186001344	folate binding site [chemical binding]; other site
707186001345	uroporphyrinogen-III synthase; Reviewed; Region: hemD; PRK05928
707186001346	Uroporphyrinogen-III synthase (HemD) catalyzes the asymmetrical cyclization of tetrapyrrole (linear) to uroporphyrinogen-III, the fourth step in the biosynthesis of heme. This ubiquitous enzyme is present in eukaryotes, bacteria and archaea. Mutations in...; Region: HemD; cd06578
707186001347	active site
707186001348	MECDP_synthase (2-C-methyl-D-erythritol-2,4-cyclodiphosphate synthase), encoded by the ispF gene, catalyzes the formation of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (MEC) in the non-mevalonate deoxyxylulose (DOXP) pathway for isoprenoid biosynthesis; Region: MECDP_synthase; cd00554
707186001349	homotrimer interaction site [polypeptide binding]; other site
707186001350	zinc binding site [ion binding]; other site
707186001351	CDP-binding sites; other site
707186001352	Sulfite reductase, alpha subunit (flavoprotein) [Inorganic ion transport and metabolism]; Region: CysJ; COG0369
707186001353	Ferredoxin reductase (FNR), an FAD and NAD(P) binding protein, was intially identified as a chloroplast reductase activity, catalyzing the electron transfer from reduced iron-sulfur protein ferredoxin to NADP+ as the final step in the electron transport...; Region: FNR_like; cl06868
707186001354	FAD binding pocket [chemical binding]; other site
707186001355	conserved FAD binding motif [chemical binding]; other site
707186001356	phosphate binding motif [ion binding]; other site
707186001357	beta-alpha-beta structure motif; other site
707186001358	NAD binding pocket [chemical binding]; other site
707186001359	30S ribosomal protein S10; Reviewed; Region: rpsJ; PRK00596
707186001360	elongation factor G; Reviewed; Region: PRK12739
707186001361	Elongation factor G (EF-G) family involved in both the elongation and ribosome recycling phases of protein synthesis; Region: EF-G; cd01886
707186001362	G1 box; other site
707186001363	putative GEF interaction site [polypeptide binding]; other site
707186001364	GTP/Mg2+ binding site [chemical binding]; other site
707186001365	Switch I region; other site
707186001366	G2 box; other site
707186001367	G3 box; other site
707186001368	Switch II region; other site
707186001369	G4 box; other site
707186001370	G5 box; other site
707186001371	EFG_mtEFG_II: this subfamily represents the domain II of elongation factor G (EF-G) in bacteria and, the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2)_like proteins found in eukaryotes. During the process of peptide synthesis...; Region: EFG_mtEFG_II; cd04088
707186001372	EFG_mtEFG1_IV: domains similar to domain IV of the bacterial translational elongation factor (EF) EF-G. Included in this group is a domain of mitochondrial Elongation factor G1 (mtEFG1) proteins homologous to domain IV of EF-G. Eukaryotic cells harbor 2...; Region: EFG_mtEFG1_IV; cd01434
707186001373	EFG_mtEFG_C: domains similar to the C-terminal domain of the bacterial translational elongation factor (EF) EF-G.  Included in this group is the C-terminus of mitochondrial Elongation factor G1 (mtEFG1) and G2 (mtEFG2) proteins. Eukaryotic cells harbor 2...; Region: EFG_mtEFG_C; cd03713
707186001374	30S ribosomal protein S7; Validated; Region: PRK05302
707186001375	S12-like family, 30S ribosomal protein S12 subfamily; S12 is located at the interface of the large and small ribosomal subunits of prokaryotes, chloroplasts and mitochondria, where it plays an important role in both tRNA and ribosomal subunit...; Region: Ribosomal_S12; cd03368
707186001376	S17 interaction site [polypeptide binding]; other site
707186001377	S8 interaction site; other site
707186001378	16S rRNA interaction site [nucleotide binding]; other site
707186001379	streptomycin interaction site [chemical binding]; other site
707186001380	23S rRNA interaction site [nucleotide binding]; other site
707186001381	aminoacyl-tRNA interaction site (A-site) [nucleotide binding]; other site
707186001382	Periplasmic protease [Cell envelope biogenesis, outer membrane]; Region: Prc; COG0793
707186001383	PDZ domain of C-terminal processing-, tail-specific-, and tricorn proteases, which function in posttranslational protein processing, maturation, and disassembly or degradation, in Bacteria, Archaea, and plant chloroplasts. May be responsible for...; Region: PDZ_CTP_protease; cd00988
707186001384	protein binding site [polypeptide binding]; other site
707186001385	C-terminal processing peptidase; serine protease family S41; Region: Peptidase_S41_CPP; cd07560
707186001386	Catalytic dyad [active]
707186001387	C-terminal domain of tail specific protease (DUF3340); Region: DUF3340; pfam11818
707186001388	Chlamydia 15 kDa cysteine-rich outer membrane protein (CRPA); Region: CRPA; pfam05745
707186001389	Chlamydia cysteine-rich outer membrane protein 6; Region: Chlam_OMP6; pfam03504
707186001390	Domain of unknown function DUF11; Region: DUF11; pfam01345
707186001391	Domain of unknown function DUF11; Region: DUF11; pfam01345
707186001392	Chlamydia cysteine-rich outer membrane protein 3; Region: Chlam_OMP3; pfam03503
707186001393	glutamyl-tRNA synthetase; Reviewed; Region: gltX; PRK01406
707186001394	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
707186001395	HIGH motif; other site
707186001396	catalytic core domain of discriminating glutamyl-tRNA synthetase; Region: GluRS_core; cd00808
707186001397	active site
707186001398	KMSKS motif; other site
707186001399	Helix-turn-helix domain; Region: HTH_17; pfam12728
707186001400	Helix-turn-helix domain; Region: HTH_17; cl17695
707186001401	single-stranded-DNA-specific exonuclease RecJ; Region: recJ; TIGR00644
707186001402	DHH family; Region: DHH; pfam01368
707186001403	DHHA1 domain; Region: DHHA1; pfam02272
707186001404	bifunctional preprotein translocase subunit SecD/SecF; Reviewed; Region: PRK12911
707186001405	protein-export membrane protein, SecD/SecF family; Region: 2A0604s01; TIGR00916
707186001406	Protein export membrane protein; Region: SecD_SecF; pfam02355
707186001407	undecaprenyl pyrophosphate synthase; Provisional; Region: PRK14840
707186001408	Undecaprenyl pyrophosphate synthase [Lipid metabolism]; Region: UppS; COG0020
707186001409	catalytic residue [active]
707186001410	putative FPP diphosphate  binding site; other site
707186001411	putative FPP binding hydrophobic cleft; other site
707186001412	dimer interface [polypeptide binding]; other site
707186001413	putative IPP diphosphate binding site; other site
707186001414	Cytidylyltransferase family; Region: CTP_transf_1; pfam01148
707186001415	CDP-diglyceride synthetase [Lipid metabolism]; Region: CdsA; COG0575
707186001416	Cytidylate kinase [Nucleotide transport and metabolism]; Region: Cmk; COG0283
707186001417	Cytidine monophosphate kinase (CMPK) catalyzes the reversible phosphorylation of cytidine monophosphate (CMP) to produce cytidine diphosphate (CDP), using ATP as the preferred phosphoryl donor; Region: CMPK; cd02020
707186001418	CMP-binding site; other site
707186001419	The sites determining sugar specificity; other site
707186001420	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
707186001421	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
707186001422	putative acyl-acceptor binding pocket; other site
707186001423	arginine-tRNA ligase; Region: PLN02286
707186001424	Arginyl tRNA synthetase N terminal domain; Region: Arg_tRNA_synt_N; pfam03485
707186001425	catalytic core domain of arginyl-tRNA synthetases; Region: ArgRS_core; cd00671
707186001426	active site
707186001427	HIGH motif; other site
707186001428	KMSK motif region; other site
707186001429	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
707186001430	tRNA binding surface [nucleotide binding]; other site
707186001431	anticodon binding site; other site
707186001432	UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Region: murA; TIGR01072
707186001433	UDP-N-acetylglucosamine enolpyruvyl transferase catalyzes enolpyruvyl transfer as part of the first step in the biosynthesis of peptidoglycan, a component of the bacterial cell wall. The reaction is phosphoenolpyruvate + UDP-N-acetyl-D-glucosamine =...; Region: UdpNAET; cd01555
707186001434	hinge; other site
707186001435	active site
707186001436	Domain of Unknown Function (DUF1547); Region: DUF1547; pfam07577
707186001437	Domain of Unknown Function (DUF1547); Region: DUF1547; pfam07577
707186001438	DNA-binding regulatory protein, YebC/PmpR family; Region: TIGR01033
707186001439	Acetyltransferases [General function prediction only]; Region: RimI; COG0456
707186001440	N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; Region: NAT_SF; cd04301
707186001441	Coenzyme A binding pocket [chemical binding]; other site
707186001442	PCRF domain; Region: PCRF; pfam03462
707186001443	Protein chain release factor B [Translation, ribosomal structure and biogenesis]; Region: PrfB; COG1186
707186001444	RF-1 domain; Region: RF-1; pfam00472
707186001445	SWIB-domain-containing proteins implicated in chromatin remodeling [Chromatin structure and dynamics]; Region: COG5531
707186001446	SWI complex, BAF60b domains; Region: SWIB; smart00151
707186001447	Bacillus subtilis YkuE and related proteins, C-terminal metallophosphatase domain; Region: MPP_YkuE_C; cd07385
707186001448	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
707186001449	putative active site [active]
707186001450	putative metal binding site [ion binding]; other site
707186001451	CDP-ME synthetase is involved in mevalonate-independent isoprenoid production; Region: CDP-ME_synthetase; cd02516
707186001452	substrate binding site; other site
707186001453	dimer interface; other site
707186001454	tRNA pseudouridine synthase A; Validated; Region: truA; PRK00021
707186001455	Eukaryotic and bacterial pseudouridine synthases similar to E.  coli TruA; Region: PseudoU_synth_EcTruA; cd02570
707186001456	dimerization interface 3.5A [polypeptide binding]; other site
707186001457	active site
707186001458	Predicted phosphatase/phosphohexomutase [General function prediction only]; Region: COG0637
707186001459	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
707186001460	active site
707186001461	motif I; other site
707186001462	motif II; other site
707186001463	Signal transduction histidine kinase, nitrogen specific [Signal transduction mechanisms]; Region: NtrB; COG3852
707186001464	PAS domain; Region: PAS; smart00091
707186001465	Histidine Kinase A (dimerization/phosphoacceptor) domain; Histidine Kinase A dimers are formed through parallel association of 2 domains creating 4-helix bundles; usually these domains contain a conserved His residue and are activated via...; Region: HisKA; cd00082
707186001466	dimer interface [polypeptide binding]; other site
707186001467	phosphorylation site [posttranslational modification]
707186001468	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
707186001469	ATP binding site [chemical binding]; other site
707186001470	Mg2+ binding site [ion binding]; other site
707186001471	G-X-G motif; other site
707186001472	Signal receiver domain; originally thought to be unique to bacteria (CheY, OmpR, NtrC, and PhoB), now recently identified in eukaroytes ETR1 Arabidopsis thaliana; this domain receives the signal from the sensor partner in a two-component systems; Region: REC; cd00156
707186001473	Response regulator receiver domain; Region: Response_reg; pfam00072
707186001474	active site
707186001475	phosphorylation site [posttranslational modification]
707186001476	intermolecular recognition site; other site
707186001477	dimerization interface [polypeptide binding]; other site
707186001478	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707186001479	ATPases associated with a variety of cellular activities; Region: AAA; smart00382
707186001480	Walker A motif; other site
707186001481	ATP binding site [chemical binding]; other site
707186001482	Walker B motif; other site
707186001483	arginine finger; other site
707186001484	Type I restriction enzyme R protein N terminus (HSDR_N); Region: HSDR_N_2; pfam13588
707186001485	Recombination protein O N terminal; Region: RecO_N; pfam11967
707186001486	Recombinational DNA repair protein (RecF pathway) [DNA replication, recombination, and repair]; Region: RecO; COG1381
707186001487	Recombination protein O C terminal; Region: RecO_C; pfam02565
707186001488	potential protein location (hypothetical protein G11222_02465 [Chlamydia trachomatis G/11222]) that overlaps RNA (tRNA-L)
707186001489	Uncharacterized conserved protein [Function unknown]; Region: COG1723
707186001490	hypothetical protein; Provisional; Region: PRK14377
707186001491	phenylalanyl-tRNA synthetase subunit beta; Reviewed; Region: pheT; PRK00629
707186001492	tRNA-binding-domain-containing prokaryotic phenylalanly tRNA synthetase (PheRS) beta chain.  PheRS aminoacylate phenylalanine transfer RNAs (tRNAphe). PheRSs belong structurally to class II aminoacyl tRNA synthetases (aaRSs) but, as they aminoacylate...; Region: tRNA_bind_bactPheRS; cd02796
707186001493	putative tRNA-binding site [nucleotide binding]; other site
707186001494	B3/4 domain; Region: B3_4; pfam03483
707186001495	tRNA synthetase B5 domain; Region: B5; pfam03484
707186001496	Phenylalanyl-tRNA synthetase (PheRS) beta chain core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure. While class II aaRSs generally aminoacylate the 3'-OH ribose of the appropriate tRNA,  PheRS is an...; Region: PheRS_beta_core; cd00769
707186001497	dimer interface [polypeptide binding]; other site
707186001498	motif 1; other site
707186001499	motif 3; other site
707186001500	motif 2; other site
707186001501	Ferredoxin-fold anticodon binding domain; Region: FDX-ACB; pfam03147
707186001502	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
707186001503	Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair]; Region: Ada; COG0350
707186001504	The DNA repair protein O6-alkylguanine-DNA alkyltransferase (ATase; also known as AGT, AGAT and MGMT) reverses O6-alkylation DNA damage by transferring O6-alkyl adducts to an active site cysteine irreversibly, without inducing DNA strand breaks. ATases...; Region: ATase; cd06445
707186001505	DNA binding site [nucleotide binding]
707186001506	active site
707186001507	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppC; COG1173
707186001508	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
707186001509	dimer interface [polypeptide binding]; other site
707186001510	conserved gate region; other site
707186001511	putative PBP binding loops; other site
707186001512	ABC-ATPase subunit interface; other site
707186001513	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cl00427
707186001514	ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppB; COG0601
707186001515	ABC-type dipeptide transport system, periplasmic component [Amino acid transport and metabolism]; Region: DdpA; COG0747
707186001516	The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold; Region: PBP2_NikA_DppA_OppA_like; cl01709
707186001517	Predicted xylanase/chitin deacetylase [Carbohydrate transport and metabolism]; Region: CDA1; COG0726
707186001518	Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands; Region: CE4_NodB_like_5s_6s; cd10918
707186001519	putative active site [active]
707186001520	putative metal binding site [ion binding]; other site
707186001521	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
707186001522	binding surface
707186001523	TPR motif; other site
707186001524	Ferrochelatase, N-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_N; cd03411
707186001525	Protoheme ferro-lyase (ferrochelatase) [Coenzyme metabolism]; Region: HemH; COG0276
707186001526	C-terminal domain interface [polypeptide binding]; other site
707186001527	active site
707186001528	Ferrochelatase, C-terminal domain: Ferrochelatase (protoheme ferrolyase or HemH) is the terminal enzyme of the heme biosynthetic pathway. It catalyzes the insertion of ferrous iron into the protoporphyrin IX ring yielding protoheme. This enzyme is...; Region: Ferrochelatase_C; cd00419
707186001529	active site
707186001530	N-terminal domain interface [polypeptide binding]; other site
707186001531	ABC-type amino acid transport/signal transduction systems, periplasmic component/domain [Amino acid transport and metabolism / Signal transduction mechanisms]; Region: HisJ; COG0834
707186001532	Bacterial periplasmic transport systems use membrane-bound complexes and substrate-bound, membrane-associated, periplasmic binding proteins (PBPs) to transport a wide variety of  substrates, such as, amino acids, peptides, sugars, vitamins and inorganic...; Region: PBPb; cd00134
707186001533	substrate binding pocket [chemical binding]; other site
707186001534	membrane-bound complex binding site; other site
707186001535	hinge residues; other site
707186001536	Conserved hypothetical protein 95; Region: Cons_hypoth95; pfam03602
707186001537	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
707186001538	S-adenosylmethionine binding site [chemical binding]; other site
707186001539	Predicted phosphohydrolase [General function prediction only]; Region: COG1768
707186001540	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
707186001541	ADP-glucose pyrophosphorylase [Carbohydrate transport and metabolism]; Region: GlgC; COG0448
707186001542	ADP-glucose pyrophosphorylase is involved in the biosynthesis of glycogen or starch; Region: ADP_Glucose_PP; cd02508
707186001543	ligand binding site; other site
707186001544	oligomer interface; other site
707186001545	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
707186001546	Glucose-1-phosphate adenylyltransferase, C-terminal Left-handed parallel beta helix (LbH) domain: Glucose-1-phosphate adenylyltransferase is also known as ADP-glucose synthase or ADP-glucose pyrophosphorylase. It catalyzes the first committed and...; Region: LbH_G1P_AT_C; cd04651
707186001547	N-terminal domain interface [polypeptide binding]; other site
707186001548	sulfate 1 binding site; other site
707186001549	transcription termination factor Rho; Region: rho; TIGR00767
707186001550	Rho termination factor, N-terminal domain; Region: Rho_N; pfam07498
707186001551	Rho_CSD: Rho protein cold-shock domain (CSD). Rho protein is a transcription termination factor in most bacteria. In bacteria, there are two distinct mechanisms for mRNA transcription termination. In intrinsic termination, RNA polymerase and nascent mRNA...; Region: Rho_CSD; cd04459
707186001552	RNA binding site [nucleotide binding]; other site
707186001553	Transcription termination factor rho is a bacterial ATP-dependent RNA/DNA helicase. It is a homohexamer. Each monomer consists of an N-terminal domain of the OB fold, which is responsible for binding to cysteine rich nucleotides. This alignment is of the...; Region: rho_factor; cd01128
707186001554	multimer interface [polypeptide binding]; other site
707186001555	Walker A motif; other site
707186001556	ATP binding site [chemical binding]; other site
707186001557	Walker B motif; other site
707186001558	Dephospho-CoA kinase [Coenzyme metabolism]; Region: CoaE; COG0237
707186001559	Dephospho-coenzyme A kinase (DPCK, EC 2.7.1.24) catalyzes the phosphorylation of dephosphocoenzyme A (dCoA) to yield CoA, which is the final step in CoA biosynthesis; Region: DPCK; cd02022
707186001560	CoA-binding site [chemical binding]; other site
707186001561	ATP-binding [chemical binding]; other site
707186001562	DNA polymerase I; Provisional; Region: PRK05755
707186001563	PIN domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: PIN_53EXO; cd09859
707186001564	active site
707186001565	metal binding site 1 [ion binding]; metal-binding site
707186001566	putative 5' ssDNA interaction site; other site
707186001567	metal binding site 3; metal-binding site
707186001568	metal binding site 2 [ion binding]; metal-binding site
707186001569	H3TH domain of the 5'-3' exonuclease of Taq DNA polymerase I and homologs; Region: H3TH_53EXO; cd09898
707186001570	putative DNA binding site [nucleotide binding]; other site
707186001571	putative metal binding site [ion binding]; other site
707186001572	3'-5' exonuclease; Region: 35EXOc; smart00474
707186001573	active site
707186001574	substrate binding site [chemical binding]; other site
707186001575	catalytic site [active]
707186001576	Polymerase I functions primarily to fill DNA gaps that arise during DNA repair, recombination and replication; Region: DNA_pol_A_pol_I_C; cd08637
707186001577	active site
707186001578	DNA binding site [nucleotide binding]
707186001579	catalytic site [active]
707186001580	Periplasmic serine proteases (ClpP class) [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: SppA; COG0616
707186001581	Signal peptide peptidase A (SppA), a serine protease, has catalytic Ser-Lys dyad; Region: S49_Sppa_N_C; cd07023
707186001582	tandem repeat interface [polypeptide binding]; other site
707186001583	oligomer interface [polypeptide binding]; other site
707186001584	active site residues [active]
707186001585	TLC ATP/ADP transporter; Region: TLC; pfam03219
707186001586	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
707186001587	replicative DNA helicase; Provisional; Region: PRK06321
707186001588	DnaB-like helicase N terminal domain; Region: DnaB; pfam00772
707186001589	DnaB helicase C terminal domain. The hexameric helicase DnaB unwinds the DNA duplex at the  chromosome replication fork. Although the mechanism by which DnaB both couples ATP hydrolysis to translocation along DNA and denatures the duplex is unknown, a...; Region: DnaB_C; cd00984
707186001590	Walker A motif; other site
707186001591	ATP binding site [chemical binding]; other site
707186001592	Walker B motif; other site
707186001593	DNA binding loops [nucleotide binding]
707186001594	tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA; Validated; Region: PRK05192
707186001595	tRNA (uracil-5-)-methyltransferase Gid; Reviewed; Region: PRK05335
707186001596	NAD(FAD)-utilizing enzyme possibly involved in translation [Translation, ribosomal structure and biogenesis]; Region: Gid; COG1206
707186001597	GidA associated domain 3; Region: GIDA_assoc_3; pfam13932
707186001598	Lipoate-protein ligase A [Coenzyme metabolism]; Region: LplA; COG0095
707186001599	Nucleoside diphosphate kinase Group I (NDPk_I)-like: NDP kinase domains are present in a large family of structurally and functionally conserved proteins from bacteria to humans that generally catalyze the transfer of gamma-phosphates of a nucleoside...; Region: NDPk_I; cd04413
707186001600	active site
707186001601	multimer interface [polypeptide binding]; other site
707186001602	Holliday junction DNA helicase RuvA; Reviewed; Region: ruvA; PRK00116
707186001603	RuvA N terminal domain; Region: RuvA_N; pfam01330
707186001604	Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. HJR's occur in archaea, bacteria, and in the mitochondria of certain fungi, however this CD...; Region: RuvC_resolvase; cd00529
707186001605	active site
707186001606	putative DNA-binding cleft [nucleotide binding]; other site
707186001607	dimer interface [polypeptide binding]; other site
707186001608	Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism]; Region: GapA; COG0057
707186001609	Glyceraldehyde 3-phosphate dehydrogenase, NAD binding domain; Region: Gp_dh_N; pfam00044
707186001610	Glyceraldehyde 3-phosphate dehydrogenase, C-terminal domain; Region: Gp_dh_C; pfam02800
707186001611	Ribosomal protein L17 [Translation, ribosomal structure and biogenesis]; Region: RplQ; COG0203
707186001612	DNA-directed RNA polymerase, alpha subunit, bacterial and chloroplast-type; Region: rpoA; TIGR02027
707186001613	N-terminal domain of the Alpha subunit of Bacterial RNA polymerase; Region: RNAP_alpha_NTD; cd06928
707186001614	alphaNTD - beta interaction site [polypeptide binding]; other site
707186001615	alphaNTD homodimer interface [polypeptide binding]; other site
707186001616	alphaNTD - beta' interaction site [polypeptide binding]; other site
707186001617	Bacterial RNA polymerase, alpha chain C terminal domain; Region: RNA_pol_A_CTD; pfam03118
707186001618	30S ribosomal protein S11; Validated; Region: PRK05309
707186001619	30S ribosomal protein S13; Validated; Region: rpsM; PRK05179
707186001620	30S ribosomal protein S13; Region: bact_S13; TIGR03631
707186001621	preprotein translocase subunit SecY; Reviewed; Region: secY; PRK09204
707186001622	SecY translocase; Region: SecY; pfam00344
707186001623	ribosomal protein L15, bacterial/organelle; Region: rplO_bact; TIGR01071
707186001624	ribosomal protein S5, bacterial/organelle type; Region: rpsE_bact; TIGR01021
707186001625	Ribosomal protein S5, N-terminal domain; Region: Ribosomal_S5; pfam00333
707186001626	Ribosomal protein S5, C-terminal domain; Region: Ribosomal_S5_C; pfam03719
707186001627	Ribosomal L18/L5e:  L18 (L5e) is a ribosomal protein found in the central protuberance (CP) of the large subunit. L18 binds 5S rRNA and induces a conformational change that stimulates the binding of L5 to 5S rRNA. Association of 5S rRNA with 23S rRNA...; Region: Ribosomal_L18_L5e; cd00432
707186001628	5S rRNA interface [nucleotide binding]; other site
707186001629	23S rRNA interface [nucleotide binding]; other site
707186001630	L5 interface [polypeptide binding]; other site
707186001631	50S ribosomal protein L6; Validated; Region: rplF; PRK05498
707186001632	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
707186001633	Ribosomal protein L6; Region: Ribosomal_L6; pfam00347
707186001634	30S ribosomal protein S8; Validated; Region: rpsH; PRK00136
707186001635	50S ribosomal protein L5; Validated; Region: rplE; PRK00010
707186001636	Ribosomal protein L5; Region: Ribosomal_L5; pfam00281
707186001637	ribosomal L5P family C-terminus; Region: Ribosomal_L5_C; pfam00673
707186001638	Ribosomal protein L24 [Translation, ribosomal structure and biogenesis]; Region: RplX; COG0198
707186001639	KOW motif of Ribosomal Protein L26; Region: KOW_RPL26; cd06089
707186001640	RNA binding site [nucleotide binding]; other site
707186001641	50S ribosomal protein L14; Validated; Region: rplN; PRK05483
707186001642	30S ribosomal protein S17; Reviewed; Region: rpsQ; PRK05610
707186001643	Ribosomal L29 protein/HIP.  L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals.  L29 is located on the surface of the large ribosomal subunit, where it...; Region: Ribosomal_L29_HIP; cd00427
707186001644	23S rRNA interface [nucleotide binding]; other site
707186001645	putative translocon interaction site; other site
707186001646	signal recognition particle (SRP54) interaction site; other site
707186001647	L23 interface [polypeptide binding]; other site
707186001648	trigger factor interaction site; other site
707186001649	Ribosomal_L16_L10e: L16 is an essential protein in the large ribosomal subunit of bacteria, mitochondria, and chloroplasts. Large subunits that lack L16 are defective in peptidyl transferase activity, peptidyl-tRNA hydrolysis activity, association with...; Region: Ribosomal_L16_L10e; cd01433
707186001650	23S rRNA interface [nucleotide binding]; other site
707186001651	5S rRNA interface [nucleotide binding]; other site
707186001652	putative antibiotic binding site [chemical binding]; other site
707186001653	L25 interface [polypeptide binding]; other site
707186001654	L27 interface [polypeptide binding]; other site
707186001655	ribosomal protein S3, bacterial type; Region: rpsC_bact; TIGR01009
707186001656	K homology RNA-binding (KH) domain of the prokaryotic 30S small ribosomal subunit protein S3. S3  is part of the head region of the 30S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel.  The KH...; Region: 30S_S3_KH; cd02412
707186001657	G-X-X-G motif; other site
707186001658	Ribosomal protein S3, C-terminal domain; Region: Ribosomal_S3_C; pfam00189
707186001659	Ribosomal protein L22/L17e.  L22 (L17 in eukaryotes) is a core protein of the large ribosomal subunit.  It is the only ribosomal protein that interacts with all six domains of 23S rRNA, and is one of the proteins important for directing the proper...; Region: Ribosomal_L22; cd00336
707186001660	putative translocon binding site; other site
707186001661	protein-rRNA interface [nucleotide binding]; other site
707186001662	30S ribosomal protein S19; Reviewed; Region: rpsS; PRK00357
707186001663	50S ribosomal protein L2; Validated; Region: rplB; PRK09374
707186001664	Ribosomal Proteins L2, RNA binding domain; Region: Ribosomal_L2; pfam00181
707186001665	Ribosomal Proteins L2, C-terminal domain; Region: Ribosomal_L2_C; pfam03947
707186001666	Ribosomal protein L23 [Translation, ribosomal structure and biogenesis]; Region: RplW; COG0089
707186001667	50S ribosomal protein L4; Provisional; Region: rplD; PRK05319
707186001668	50S ribosomal protein L3; Validated; Region: rplC; PRK00001
707186001669	methionyl-tRNA formyltransferase; Reviewed; Region: fmt; PRK00005
707186001670	Methionyl-tRNA formyltransferase, N-terminal hydrolase domain; Region: FMT_core_Met-tRNA-FMT_N; cd08646
707186001671	putative active site [active]
707186001672	substrate binding site [chemical binding]; other site
707186001673	putative cosubstrate binding site; other site
707186001674	catalytic site [active]
707186001675	C-terminal domain of Formyltransferase and other enzymes; Region: Met_tRNA_FMT_C; cd08704
707186001676	substrate binding site [chemical binding]; other site
707186001677	Acyl-[acyl carrier protein]; Region: LpxA; COG1043
707186001678	UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic...; Region: LbH_UDP-GlcNAc_AT; cd03351
707186001679	active site
707186001680	FabZ is a 17kD beta-hydroxyacyl-acyl carrier protein (ACP) dehydratase that primarily catalyzes the dehydration of beta-hydroxyacyl-ACP to trans-2-acyl-ACP, the third step in the elongation phase of the bacterial/ plastid, type II, fatty-acid...; Region: FabZ; cd01288
707186001681	UDP-3-O-acyl-N-acetylglucosamine deacetylase [Cell envelope biogenesis, outer membrane]; Region: LpxC; COG0774
707186001682	UDP-3-O-acyl N-acetylglycosamine deacetylase; Region: LpxC; pfam03331
707186001683	Apolipoprotein N-acyltransferase [Cell envelope biogenesis, outer membrane]; Region: Lnt; COG0815
707186001684	Apolipoprotein N-acyl transferase (class 9 nitrilases); Region: ALP_N-acyl_transferase; cd07571
707186001685	putative active site [active]
707186001686	catalytic triad [active]
707186001687	putative dimer interface [polypeptide binding]; other site
707186001688	Brown fat-inducible thioesterase (BFIT).  Brain acyl-CoA hydrolase (BACH).  These enzymes deacylate long-chain fatty acids by hydrolyzing acyl-CoA thioesters to free fatty acids and CoA-SH. Eukaryotic members of this family are expressed in brain, testis; Region: BFIT_BACH; cd03442
707186001689	DNA polymerase III subunit epsilon; Validated; Region: PRK06310
707186001690	DEDDh 3'-5' exonuclease domain family; Region: DEDDh; cd06127
707186001691	active site
707186001692	catalytic site [active]
707186001693	substrate binding site [chemical binding]; other site
707186001694	Protein of unknown function (DUF3820); Region: DUF3820; cl01411
707186001695	Uncharacterized P-loop hydrolase UPF0079; Region: UPF0079; pfam02367
707186001696	Protein of unknown function (DUF2709); Region: DUF2709; pfam10915
707186001697	TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox...; Region: TRX_family; cd02947
707186001698	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
707186001699	catalytic residues [active]
707186001700	Predicted rRNA methylase (SpoU class) [Translation, ribosomal structure and biogenesis]; Region: CspR; COG0219
707186001701	FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones]; Region: FkpA; COG0545
707186001702	Domain amino terminal to FKBP-type peptidyl-prolyl isomerase; Region: FKBP_N; pfam01346
707186001703	FKBP-type peptidyl-prolyl cis-trans isomerase; Region: FKBP_C; pfam00254
707186001704	aspartyl-tRNA synthetase; Validated; Region: aspS; PRK00476
707186001705	EcAspRS_like_N: N-terminal, anticodon recognition domain of the type found in Escherichia coli aspartyl-tRNA synthetase (AspRS), the human mitochondrial (mt) AspRS-2, the discriminating (D) Thermus thermophilus AspRS-1, and the nondiscriminating (ND)...; Region: EcAspRS_like_N; cd04317
707186001706	dimer interface [polypeptide binding]; other site
707186001707	anticodon binding site; other site
707186001708	Asp tRNA synthetase (aspRS) class II core domain. Class II assignment is based upon its structure and the presence of three characteristic sequence motifs. AspRS is a homodimer, which attaches a specific amino acid to the 3' OH group of ribose of...; Region: AspRS_core; cd00777
707186001709	homodimer interface [polypeptide binding]; other site
707186001710	motif 1; other site
707186001711	active site
707186001712	motif 2; other site
707186001713	GAD domain; Region: GAD; pfam02938
707186001714	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
707186001715	active site
707186001716	motif 3; other site
707186001717	histidyl-tRNA synthetase; Reviewed; Region: hisS; PRK00037
707186001718	Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain. HisRS is a homodimer. It is responsible for the attachment of histidine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for...; Region: HisRS-like_core; cd00773
707186001719	dimer interface [polypeptide binding]; other site
707186001720	motif 1; other site
707186001721	active site
707186001722	motif 2; other site
707186001723	motif 3; other site
707186001724	HisRS Histidyl-anticodon binding domain. HisRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: HisRS_anticodon; cd00859
707186001725	anticodon binding site; other site
707186001726	Sugar phosphate permease [Carbohydrate transport and metabolism]; Region: UhpC; COG2271
707186001727	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
707186001728	putative substrate translocation pore; other site
707186001729	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
707186001730	DNA polymerase III subunit alpha; Validated; Region: dnaE; PRK05673
707186001731	Polymerase and Histidinol Phosphatase domain of alpha-subunit of bacterial polymerase III DnaE3; Region: PHP_PolIIIA_DnaE3; cd12113
707186001732	active site
707186001733	PHP Thumb interface [polypeptide binding]; other site
707186001734	metal binding site [ion binding]; metal-binding site
707186001735	DnaE_OBF: A subfamily of OB folds corresponding to the C-terminal OB-fold nucleic acid binding domain of Thermus aquaticus and Escherichia coli type C replicative DNA polymerase III alpha subunit (DnaE). The DNA polymerase holoenzyme of E. coli contains...; Region: DnaE_OBF; cd04485
707186001736	generic binding surface I; other site
707186001737	generic binding surface II; other site
707186001738	TPR repeat; Region: TPR_11; pfam13414
707186001739	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
707186001740	binding surface
707186001741	TPR motif; other site
707186001742	DNA uptake lipoprotein [General function prediction only]; Region: ComL; COG4105
707186001743	Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms]; Region: RsbW; COG2172
707186001744	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cl00075
707186001745	Mg2+ binding site [ion binding]; other site
707186001746	D-alanyl-D-alanine carboxypeptidase [Cell envelope biogenesis, outer membrane]; Region: DacC; COG1686
707186001747	Beta-lactamase enzyme family; Region: Beta-lactamase2; cl17872
707186001748	potential frameshift: common BLAST hit: gi|237804904|ref|YP_002889058.1| putative methyltransferase
707186001749	branched-chain amino acid uptake carrier; Region: livcs; TIGR00796
707186001750	Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair]; Region: HepA; COG0553
707186001751	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
707186001752	ATP binding site [chemical binding]; other site
707186001753	putative Mg++ binding site [ion binding]; other site
707186001754	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
707186001755	ATP-binding site [chemical binding]; other site
707186001756	dihydrolipoamide dehydrogenase; Validated; Region: PRK06327
707186001757	Anaerobic glycerol-3-phosphate dehydrogenase [Amino acid transport and metabolism]; Region: GlpB; cl17730
707186001758	Pyridine nucleotide-disulphide oxidoreductase; Region: Pyr_redox; pfam00070
707186001759	Pyridine nucleotide-disulphide oxidoreductase, dimerisation domain; Region: Pyr_redox_dim; pfam02852
707186001760	lipoate synthase; Region: lipA; TIGR00510
707186001761	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cd01335
707186001762	FeS/SAM binding site; other site
707186001763	Type III secretory pathway, lipoprotein EscJ [Intracellular trafficking and secretion]; Region: EscJ; COG4669
707186001764	type III secretion system protein; Validated; Region: PRK06328
707186001765	Flagellar assembly protein FliH; Region: FliH; pfam02108
707186001766	type III secretion system protein; Reviewed; Region: PRK09617
707186001767	Type III secretory pathway, component EscS [Intracellular trafficking and secretion]; Region: EscS; COG4794
707186001768	Type III secretory pathway, component EscT [Intracellular trafficking and secretion]; Region: EscT; COG4791
707186001769	Protein of unknown function (DUF1494); Region: DUF1494; pfam07379
707186001770	Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulG; COG2165
707186001771	Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulF; COG1459
707186001772	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
707186001773	Type II secretion system (T2SS), protein F; Region: T2SF; pfam00482
707186001774	Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulE; COG2804
707186001775	Type II secretion system (T2SS), protein E, N-terminal domain; Region: T2SE_Nter; pfam05157
707186001776	PulE/GspE The type II secretory pathway is the main terminal branch of the general secretory pathway (GSP). It is responsible for the export the majority of Gram-negative bacterial exoenzymes and toxins. PulE is a cytoplasmic protein of the GSP, which...; Region: PulE-GspE; cd01129
707186001777	Walker A motif; other site
707186001778	ATP binding site [chemical binding]; other site
707186001779	Walker B motif; other site
707186001780	Type II secretory pathway, component PulD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulD; COG1450
707186001781	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
707186001782	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
707186001783	Xaa-Pro aminopeptidase [Amino acid transport and metabolism]; Region: PepP; COG0006
707186001784	Creatinase/Prolidase N-terminal domain; Region: Creatinase_N; pfam01321
707186001785	Similar to Prolidase and Aminopeptidase P. The members of this subfamily presumably catalyse hydrolysis of Xaa-Pro dipeptides and/or release of any N-terminal amino acid, including proline, that is linked with proline; Region: APP-like; cd01092
707186001786	active site
707186001787	DNA mismatch repair enzyme (predicted ATPase) [DNA replication, recombination, and repair]; Region: MutL; COG0323
707186001788	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
707186001789	ATP binding site [chemical binding]; other site
707186001790	Mg2+ binding site [ion binding]; other site
707186001791	G-X-G motif; other site
707186001792	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of DNA mismatch repair (MutL/MLH1/PMS2) family. This transducer domain is homologous to the second domain of the DNA gyrase B subunit, which is...; Region: MutL_Trans; cd00782
707186001793	ATP binding site [chemical binding]; other site
707186001794	MutL C terminal dimerisation domain; Region: MutL_C; pfam08676
707186001795	type III secretion low calcium response chaperone LcrH/SycD; Region: LcrH_SycD; TIGR02552
707186001796	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
707186001797	binding surface
707186001798	TPR motif; other site
707186001799	Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only]; Region: RhaT; COG0697
707186001800	EamA-like transporter family; Region: EamA; pfam00892
707186001801	EamA-like transporter family; Region: EamA; pfam00892
707186001802	threonyl-tRNA synthetase; Reviewed; Region: thrS; PRK00413
707186001803	The TGS domain, named after the ThrRS, GTPase, and SpoT/RelA proteins where it occurs, is structurally similar to ubiquitin. TGS is a small domain of about 50 amino acid residues with a predominantly beta-sheet structure. There is no direct information...; Region: TGS; cd01616
707186001804	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; smart00863
707186001805	Threonyl-tRNA synthetase (ThrRS) class II core catalytic domain. ThrRS is a homodimer. It is responsible for the attachment of threonine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: ThrRS_core; cd00771
707186001806	active site
707186001807	dimer interface [polypeptide binding]; other site
707186001808	motif 1; other site
707186001809	motif 2; other site
707186001810	motif 3; other site
707186001811	ThrRS Threonyl-anticodon binding domain. ThrRS belongs to class II aminoacyl-tRNA synthetases (aaRS). This alignment contains the anticodon binding domain, which is responsible for specificity in tRNA-binding, so that the activated amino acid is...; Region: ThrRS_anticodon; cd00860
707186001812	anticodon binding site; other site
707186001813	ATPases involved in chromosome partitioning [Cell division and chromosome partitioning]; Region: Soj; COG1192
707186001814	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
707186001815	Uncharacterized protein family (UPF0137); Region: UPF0137; pfam03677
707186001816	tryptophanyl-tRNA synthetase II; Reviewed; Region: PRK12282
707186001817	catalytic core domain of tryptophanyl-tRNA synthetase; Region: TrpRS_core; cd00806
707186001818	active site
707186001819	HIGH motif; other site
707186001820	dimer interface [polypeptide binding]; other site
707186001821	KMSKS motif; other site
707186001822	excinuclease ABC subunit B; Provisional; Region: PRK05298
707186001823	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
707186001824	ATP binding site [chemical binding]; other site
707186001825	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
707186001826	nucleotide binding region [chemical binding]; other site
707186001827	ATP-binding site [chemical binding]; other site
707186001828	Ultra-violet resistance protein B; Region: UvrB; pfam12344
707186001829	enolase; Provisional; Region: eno; PRK00077
707186001830	Enolase: Enolases are homodimeric enzymes that catalyse the reversible dehydration of 2-phospho-D-glycerate to phosphoenolpyruvate as part of the glycolytic and gluconeogenesis pathways. The reaction is facilitated by the presence of metal ions; Region: enolase; cd03313
707186001831	dimer interface [polypeptide binding]; other site
707186001832	metal binding site [ion binding]; metal-binding site
707186001833	substrate binding pocket [chemical binding]; other site
707186001834	Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription]; Region: RsbU; COG2208
707186001835	HAMP domain; Region: HAMP; pfam00672
707186001836	Stage II sporulation protein E (SpoIIE); Region: SpoIIE; pfam07228
707186001837	Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain. HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices...; Region: HAMP; cl01054
707186001838	Sigma factor PP2C-like phosphatases; Region: PP2C_SIG; smart00331
707186001839	2Fe-2S iron-sulfur cluster binding domain; Region: Fer2_3; pfam13085
707186001840	4Fe-4S dicluster domain; Region: Fer4_8; pfam13183
707186001841	potential frameshift: common BLAST hit: gi|237803021|ref|YP_002888215.1| succinate dehydrogenase flavoprotein subunit
707186001842	Succinate:quinone oxidoreductase (SQR) and Quinol:fumarate reductase (QFR) family, transmembrane subunits; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol, while QFR catalyzes the reverse reaction. SQR; Region: SQR_QFR_TM; cl00881
707186001843	Iron-sulfur protein interface; other site
707186001844	Succinate:quinone oxidoreductase (SQR) and Quinol:fumarate reductase (QFR) family, transmembrane subunits; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol, while QFR catalyzes the reverse reaction. SQR; Region: SQR_QFR_TM; cl00881
707186001845	proximal heme binding site [chemical binding]; other site
707186001846	Iron-sulfur protein interface; other site
707186001847	Succinate:quinone oxidoreductase (SQR) and Quinol:fumarate reductase (QFR) family, transmembrane subunits; SQR catalyzes the oxidation of succinate to fumarate coupled to the reduction of quinone to quinol, while QFR catalyzes the reverse reaction. SQR; Region: SQR_QFR_TM; cl00881
707186001848	TatD like proteins;  E.coli TatD is a cytoplasmic protein, shown to have magnesium dependent DNase activity; Region: TatD_DNAse; cd01310
707186001849	Predicted metal-dependent hydrolases with the TIM-barrel fold [General function prediction only]; Region: COG1099
707186001850	active site
707186001851	Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis [Posttranslational modification, protein turnover, chaperones / Energy production and conversion]; Region: COG4233
707186001852	Cytochrome c biogenesis protein [Posttranslational modification, protein turnover, chaperones]; Region: CcdA; COG0785
707186001853	Cytochrome C biogenesis protein transmembrane region; Region: DsbD; cl15788
707186001854	DsbD gamma family; DsbD gamma is the C-terminal periplasmic domain of the bacterial protein DsbD. It contains a CXXC motif in a TRX fold and shuttles the reducing potential from the membrane domain (DsbD beta) to the N-terminal periplasmic domain (DsbD...; Region: DsbDgamma; cd02953
707186001855	DsbD alpha interface [polypeptide binding]; other site
707186001856	catalytic residues [active]
707186001857	Biopolymer transport proteins [Intracellular trafficking and secretion]; Region: TolQ; COG0811
707186001858	Biopolymer transport protein [Intracellular trafficking and secretion]; Region: ExbD; COG0848
707186001859	Biopolymer transport protein ExbD/TolR; Region: ExbD; pfam02472
707186001860	translocation protein TolB; Provisional; Region: tolB; PRK01029
707186001861	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
707186001862	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
707186001863	WD40-like Beta Propeller Repeat; Region: PD40; pfam07676
707186001864	Outer membrane protein and related peptidoglycan-associated (lipo)proteins [Cell envelope biogenesis, outer membrane]; Region: OmpA; COG2885
707186001865	Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA; Region: OmpA_C-like; cd07185
707186001866	ligand binding site [chemical binding]; other site
707186001867	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
707186001868	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
707186001869	Peroxiredoxin [Posttranslational modification, protein turnover, chaperones]; Region: AhpC; COG0450
707186001870	Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides; Region: PRX_Typ2cys; cd03015
707186001871	dimer interface [polypeptide binding]; other site
707186001872	decamer (pentamer of dimers) interface [polypeptide binding]; other site
707186001873	catalytic triad [active]
707186001874	peroxidatic and resolving cysteines [active]
707186001875	Chaperonin GroEL (HSP60 family) [Posttranslational modification, protein turnover, chaperones]; Region: GroL; COG0459
707186001876	chaperonin GroEL; Reviewed; Region: groEL; PRK12849
707186001877	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG3876
707186001878	NTPase/HAM1.  This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A...; Region: HAM1; cd00515
707186001879	active site
707186001880	dimerization interface [polypeptide binding]; other site
707186001881	Family 1 of Uracil-DNA glycosylase (UDG) enzymes; Region: UDG_F1; cd10027
707186001882	ligand binding site [chemical binding]; other site
707186001883	active site
707186001884	UGI interface [polypeptide binding]; other site
707186001885	catalytic site [active]
707186001886	Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair]; Region: UvrD; COG0210
707186001887	Part of AAA domain; Region: AAA_19; pfam13245
707186001888	Family description; Region: UvrD_C_2; pfam13538
707186001889	DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog [Transcription]; Region: RpoN; COG1508
707186001890	Sigma-54 factor, Activator interacting domain (AID); Region: Sigma54_AID; pfam00309
707186001891	Sigma-54 factor, core binding domain; Region: Sigma54_CBD; pfam04963
707186001892	Sigma-54, DNA binding domain; Region: Sigma54_DBD; pfam04552
707186001893	Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C [Coenzyme metabolism]; Region: COG5424
707186001894	GTP and metal dependent enzyme involved F420 coenzyme biosynthesis (catalyzes addition of two l-glutamates to F420 precursor) [Coenzyme transport and metabolism]; Region: COG1478
707186001895	F420-0:Gamma-glutamyl ligase; Region: F420_ligase; cl00644
707186001896	Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5; Region: DHFR; cd00209
707186001897	Dihydrofolate reductase [Coenzyme metabolism]; Region: FolA; COG0262
707186001898	folate binding site [chemical binding]; other site
707186001899	NADP+ binding site [chemical binding]; other site
707186001900	7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase (HPPK). Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and amino acids as well as formyl-tRNA. Mammalian cells are able to utilize pre-formed folates after...; Region: HPPK; cd00483
707186001901	catalytic center binding site [active]
707186001902	ATP binding site [chemical binding]; other site
707186001903	DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and...; Region: DHPS; cd00739
707186001904	dihydropteroate synthase; Region: DHPS; TIGR01496
707186001905	substrate binding pocket [chemical binding]; other site
707186001906	dimer interface [polypeptide binding]; other site
707186001907	inhibitor binding site; inhibition site
707186001908	Dihydroneopterin aldolase (DHNA) and 7,8-dihydroneopterin triphosphate epimerase domain (DHNTPE); these enzymes have been designated folB and folX, respectively. Folate derivatives are essential cofactors in the biosynthesis of purines, pyrimidines, and...; Region: DHNA_DHNTPE; cd00534
707186001909	homooctamer interface [polypeptide binding]; other site
707186001910	active site
707186001911	RNA polymerase sigma factor RpoD; Validated; Region: PRK05658
707186001912	Sigma-70 factor, region 1.1; Region: Sigma70_r1_1; pfam03979
707186001913	Sigma-70 factor, region 1.2; Region: Sigma70_r1_2; pfam00140
707186001914	Sigma-70 region 2; Region: Sigma70_r2; pfam04542
707186001915	Sigma-70 region 3; Region: Sigma70_r3; pfam04539
707186001916	Sigma70, region (SR) 4 refers to the most C-terminal of four conserved domains found in Escherichia coli (Ec) sigma70, the main housekeeping sigma, and related sigma-factors (SFs). A SF is a dissociable subunit of RNA polymerase, it directs bacterial or...; Region: Sigma70_r4; cd06171
707186001917	DNA binding residues [nucleotide binding]
707186001918	Uncharacterized protein family (UPF0242); Region: UPF0242; pfam06785
707186001919	30S ribosomal protein S20; Reviewed; Region: rpsT; PRK00239
707186001920	Effector from type III secretion system; Region: Effector_1; pfam04518
707186001921	Effector from type III secretion system; Region: Effector_1; pfam04518
707186001922	Effector from type III secretion system; Region: Effector_1; pfam04518
707186001923	Protein of unknown function (DUF2586); Region: DUF2586; pfam10758
707186001924	MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins; Region: MATE_MurJ_like; cd13123
707186001925	MviN-like protein; Region: MVIN; pfam03023
707186001926	endonuclease IV; Provisional; Region: PRK01060
707186001927	AP endonuclease family 2; These endonucleases play a role in DNA repair. Cleave phosphodiester bonds at apurinic or apyrimidinic sites; the alignment also contains hexulose-6-phosphate isomerases, enzymes that catalyze the epimerization of...; Region: AP2Ec; cd00019
707186001928	AP (apurinic/apyrimidinic) site pocket; other site
707186001929	DNA interaction; other site
707186001930	Metal-binding active site; metal-binding site
707186001931	Ribosomal protein S4/S9 N-terminal domain; Region: Ribosomal_S4; pfam00163
707186001932	ribosomal protein S4, bacterial/organelle type; Region: rpsD_bact; TIGR01017
707186001933	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
707186001934	RNA binding surface [nucleotide binding]; other site
707186001935	putative rhodanese-related sulfurtransferase; Provisional; Region: PRK00142
707186001936	Member of the Rhodanese Homology Domain superfamily. This CD includes Escherichia coli YceA, Bacillus subtilis YbfQ, and similar uncharacterized proteins; Region: RHOD_YceA; cd01518
707186001937	active site residue [active]
707186001938	Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism]; Region: IspA; COG0142
707186001939	Trans-Isoprenyl Diphosphate Synthases, head-to-tail; Region: Trans_IPPS_HT; cd00685
707186001940	substrate binding pocket [chemical binding]; other site
707186001941	chain length determination region; other site
707186001942	substrate-Mg2+ binding site; other site
707186001943	catalytic residues [active]
707186001944	aspartate-rich region 1; other site
707186001945	active site lid residues [active]
707186001946	aspartate-rich region 2; other site
707186001947	Left-handed parallel beta-Helix (LbetaH or LbH) domain: The alignment contains 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). Proteins containing hexapeptide repeats are often enzymes...; Region: LbetaH; cl00160
707186001948	putative trimer interface [polypeptide binding]; other site
707186001949	putative CoA binding site [chemical binding]; other site
707186001950	Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription]; Region: OmpR; COG0745
707186001951	Effector domain of response regulator. Bacteria and certain eukaryotes like protozoa and higher plants use two-component signal transduction systems to detect and respond to changes in the environment. The system consists of a sensor histidine kinase and...; Region: trans_reg_C; cd00383
707186001952	DNA binding site [nucleotide binding]
707186001953	Predicted alternative thymidylate synthase [Nucleotide transport and metabolism]; Region: THY1; COG1351
707186001954	Thymidylate synthase complementing protein; Region: Thy1; cl03630
707186001955	Porphobilinogen synthase (PBGS), which is also called delta-aminolevulinic acid dehydratase (ALAD), catalyzes the condensation of two 5-aminolevulinic acid (ALA) molecules to form the pyrrole porphobilinogen (PBG), which is the second step in the...; Region: ALAD_PBGS_aspartate_rich; cd04823
707186001956	dimer interface [polypeptide binding]; other site
707186001957	active site
707186001958	aspartate-rich active site metal binding site; other site
707186001959	allosteric magnesium binding site [ion binding]; other site
707186001960	Schiff base residues; other site
707186001961	NADH:ubiquinone oxidoreductase, Na(+)-translocating, A subunit; Region: nqrA; TIGR01936
707186001962	NQRA C-terminal domain; Region: NQRA_SLBB; pfam11973
707186001963	transcript cleavage factor/unknown domain fusion protein; Validated; Region: PRK06330
707186001964	Transcription elongation factor, N-terminal; Region: GreA_GreB_N; pfam03449
707186001965	Transcription elongation factor, GreA/GreB, C-term; Region: GreA_GreB; pfam01272
707186001966	aromatic amino acid aminotransferase; Provisional; Region: PRK09257
707186001967	Aspartate aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). Pyridoxal phosphate combines with an alpha-amino acid to form a compound called a Schiff base or aldimine...; Region: AAT_like; cd00609
707186001968	pyridoxal 5'-phosphate binding site [chemical binding]; other site
707186001969	homodimer interface [polypeptide binding]; other site
707186001970	catalytic residue [active]
707186001971	rod shape-determining protein MreC; Provisional; Region: PRK14872
707186001972	rod shape-determining protein MreC; Region: MreC; pfam04085
707186001973	exodeoxyribonuclease V, beta subunit; Region: recB; TIGR00609
707186001974	Part of AAA domain; Region: AAA_19; pfam13245
707186001975	Family description; Region: UvrD_C_2; pfam13538
707186001976	Exonuclease V gamma subunit [DNA replication, recombination, and repair]; Region: RecC; COG1330
707186001977	Major Facilitator Superfamily; Region: MFS_1; pfam07690
707186001978	The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of...; Region: MFS; cd06174
707186001979	putative substrate translocation pore; other site
707186001980	DNA topoisomerase I/SWI domain fusion protein; Validated; Region: PRK06319
707186001981	TOPRIM_TopoIA_TopoI: The topoisomerase-primase (TORPIM) domain found in members of the type IA family of DNA topoisomerases (Topo IA) similar to Escherichia coli DNA topoisomerase I.   Type IA DNA topoisomerases remove (relax) negative supercoils in the...; Region: TOPRIM_TopoIA_TopoI; cd03363
707186001982	active site
707186001983	interdomain interaction site; other site
707186001984	putative metal-binding site [ion binding]; other site
707186001985	nucleotide binding site [chemical binding]; other site
707186001986	DNA Topoisomerase, subtype IA; DNA-binding, ATP-binding and catalytic domain of bacterial DNA topoisomerases I and III, and eukaryotic DNA topoisomerase III and eubacterial and archael reverse gyrases. Topoisomerases clevage single or double stranded DNA...; Region: TOP1Ac; cd00186
707186001987	domain I; other site
707186001988	DNA binding groove [nucleotide binding]
707186001989	phosphate binding site [ion binding]; other site
707186001990	domain II; other site
707186001991	domain III; other site
707186001992	nucleotide binding site [chemical binding]; other site
707186001993	catalytic site [active]
707186001994	domain IV; other site
707186001995	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
707186001996	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
707186001997	Topoisomerase DNA binding C4 zinc finger; Region: zf-C4_Topoisom; pfam01396
707186001998	SWI complex, BAF60b domains; Region: SWIB; smart00151
707186001999	putative TIM-barrel protein, nifR3 family; Region: nifR3_yhdG; TIGR00737
707186002000	Dihydrouridine synthase-like (DUS-like) FMN-binding domain. Members of this family catalyze the reduction of the 5,6-double bond of a uridine residue on tRNA. Dihydrouridine modification of tRNA is widely observed in prokaryotes and eukaryotes, and also...; Region: DUS_like_FMN; cd02801
707186002001	FMN binding site [chemical binding]; other site
707186002002	active site
707186002003	catalytic residues [active]
707186002004	substrate binding site [chemical binding]; other site
707186002005	Predicted integral membrane protein [Function unknown]; Region: COG0762
707186002006	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
707186002007	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG2849
707186002008	5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]; Region: COG0212
707186002009	5-formyltetrahydrofolate cyclo-ligase family; Region: 5-FTHF_cyc-lig; pfam01812
707186002010	recombinase A; Provisional; Region: recA; PRK09354
707186002011	RecA is a  bacterial enzyme which has roles in homologous recombination, DNA repair, and the induction of the SOS response.  RecA couples ATP hydrolysis to DNA strand exchange; Region: recA; cd00983
707186002012	hexamer interface [polypeptide binding]; other site
707186002013	Walker A motif; other site
707186002014	ATP binding site [chemical binding]; other site
707186002015	Walker B motif; other site
707186002016	Protein of unknown function (DUF1347); Region: DUF1347; pfam07079
707186002017	exodeoxyribonuclease V, alpha subunit; Region: recD; TIGR01447
707186002018	AAA domain; Region: AAA_30; pfam13604
707186002019	Family description; Region: UvrD_C_2; pfam13538
707186002020	ABC-type (unclassified) transport system, ATPase component [General function prediction only]; Region: YhbG; COG1137
707186002021	ATP-binding cassette component of YhbG transport system; Region: ABC_YhbG; cd03218
707186002022	Walker A/P-loop; other site
707186002023	ATP binding site [chemical binding]; other site
707186002024	Q-loop/lid; other site
707186002025	ABC transporter signature motif; other site
707186002026	Walker B; other site
707186002027	D-loop; other site
707186002028	H-loop/switch region; other site
707186002029	Protein of unknown function (DUF1137); Region: DUF1137; pfam06587
707186002030	3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase [Cell envelope biogenesis, outer membrane]; Region: KdsA; COG2877
707186002031	DAHP synthetase I family; Region: DAHP_synth_1; pfam00793
707186002032	potential protein location (hypothetical protein G11222_03480 [Chlamydia trachomatis G/11222]) that overlaps RNA (tRNA-R)
707186002033	Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis]; Region: RluA; COG0564
707186002034	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
707186002035	RNA binding surface [nucleotide binding]; other site
707186002036	Pseudouridine synthase, RsuA/RluD family; Region: PseudoU_synth_RluCD_like; cd02869
707186002037	active site
707186002038	hypothetical protein; Provisional; Region: PRK01064
707186002039	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
707186002040	DNA topoisomerase IV subunit A; Provisional; Region: PRK09630
707186002041	DNA Topoisomerase IV; Region: TOP4c; smart00434
707186002042	CAP-like domain; other site
707186002043	active site
707186002044	DNA topoisomerase IV subunit B; Reviewed; Region: PRK05559
707186002045	Histidine kinase-like ATPases; This family includes several ATP-binding proteins for example: histidine kinase, DNA gyrase B, topoisomerases, heat shock protein HSP90, phytochrome-like ATPases and DNA mismatch repair proteins; Region: HATPase_c; cd00075
707186002046	ATP binding site [chemical binding]; other site
707186002047	Mg2+ binding site [ion binding]; other site
707186002048	G-X-G motif; other site
707186002049	MutL_Trans: transducer domain, having a ribosomal S5 domain 2-like fold, conserved in the C-terminal domain of type II DNA topoisomerases (Topo II) and DNA mismatch repair (MutL/MLH1/PMS2) proteins. This transducer domain is homologous to the second...; Region: TopoII_MutL_Trans; cl02783
707186002050	ATP binding site [chemical binding]; other site
707186002051	TOPRIM_TopoIIA_like: topoisomerase-primase (TOPRIM) nucleotidyl transferase/hydrolase domain of the type found in proteins of the type IIA family of DNA topoisomerases similar to Saccharomyces cerevisiae Topoisomerase II. TopoIIA enzymes cut both strands...; Region: TOPRIM_TopoIIA_like; cd01030
707186002052	active site
707186002053	putative metal-binding site [ion binding]; other site
707186002054	DNA gyrase B subunit, carboxyl terminus; Region: DNA_gyraseB_C; pfam00986
707186002055	glutamyl-tRNA reductase; Validated; Region: hemA; PRK00676
707186002056	NAD(P) binding domain of amino acid dehydrogenase-like proteins; Region: NAD_bind_amino_acid_DH; cl17226
707186002057	NAD(P) binding pocket [chemical binding]; other site
707186002058	Tir chaperone protein (CesT) family; Region: CesT; pfam05932
707186002059	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
707186002060	phosphopeptide binding site; other site
707186002061	MARCKS family; Region: MARCKS; pfam02063
707186002062	Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins...; Region: FHA; cd00060
707186002063	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
707186002064	phosphopeptide binding site; other site
707186002065	FOG: FHA domain [Signal transduction mechanisms]; Region: COG1716
707186002066	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cl02429
707186002067	binding surface
707186002068	Tetratricopeptide repeat; Region: TPR_16; pfam13432
707186002069	TPR motif; other site
707186002070	type III secretion system ATPase; Provisional; Region: PRK06315
707186002071	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
707186002072	Flagellum-specific ATPase/type III secretory pathway virulence-related protein. This group of ATPases are responsible for the export of flagellum and virulence-related proteins. The bacterial flagellar motor is similar to the F0F1-ATPase, in that they...; Region: ATPase_flagellum-secretory_path_III; cd01136
707186002073	Walker A motif/ATP binding site; other site
707186002074	Walker B motif; other site
707186002075	type III secretion system protein; Validated; Region: PRK05933
707186002076	Flagellar motor switch/type III secretory pathway protein [Cell motility and secretion / Intracellular trafficking and secretion]; Region: FliN; COG1886
707186002077	Serine/Threonine protein kinases, catalytic domain; Region: S_TKc; smart00220
707186002078	Catalytic domain of Protein Kinases; Region: PKc; cd00180
707186002079	active site
707186002080	ATP binding site [chemical binding]; other site
707186002081	substrate binding site [chemical binding]; other site
707186002082	activation loop (A-loop); other site
707186002083	Type II secretory pathway, component PulD [Cell motility and secretion / Intracellular trafficking and secretion]; Region: PulD; COG1450
707186002084	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
707186002085	Bacterial type II/III secretion system short domain; Region: Secretin_N; pfam03958
707186002086	Bacterial type II and III secretion system protein; Region: Secretin; pfam00263
707186002087	Arginine kinase [Amino acid transport and metabolism]; Region: COG3869
707186002088	Phosphagen (guanidino) kinases found in bacteria; Region: bacterial_phosphagen_kinase; cd07930
707186002089	ADP binding site [chemical binding]; other site
707186002090	phosphagen binding site; other site
707186002091	substrate specificity loop; other site
707186002092	Modulator of heat shock repressor CtsR, McsA [Signal transduction    mechanisms]; Region: COG3880
707186002093	UvrB/uvrC motif; Region: UVR; pfam02151
707186002094	ribosome recycling factor; Reviewed; Region: frr; PRK00083
707186002095	Ribosome recycling factor (RRF). Ribosome recycling factor dissociates the posttermination complex, composed of the ribosome, deacylated tRNA, and mRNA, after termination of translation.  Thus ribosomes are "recycled" and ready for another...; Region: RRF; cd00520
707186002096	hinge region; other site
707186002097	UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and...; Region: AAK_UMPK-PyrH-Ec; cd04254
707186002098	putative nucleotide binding site [chemical binding]; other site
707186002099	uridine monophosphate binding site [chemical binding]; other site
707186002100	homohexameric interface [polypeptide binding]; other site
707186002101	Translation elongation factor Ts [Translation, ribosomal structure and biogenesis]; Region: Tsf; COG0264
707186002102	Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been...; Region: UBA; cl00153
707186002103	Elongation factor TS; Region: EF_TS; pfam00889
707186002104	Elongation factor TS; Region: EF_TS; pfam00889
707186002105	Ribosomal protein S2 (RPS2), involved in formation of the translation initiation complex, where it might contact the messenger RNA and several components of the ribosome. It has been shown that in Escherichia coli RPS2 is essential for the binding of...; Region: RPS2; cd01425
707186002106	rRNA interaction site [nucleotide binding]; other site
707186002107	S8 interaction site; other site
707186002108	putative laminin-1 binding site; other site
707186002109	Chlamydia major outer membrane protein; Region: Chlam_OMP; pfam01308
707186002110	Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane]; Region: FtsI; COG0768
707186002111	Penicillin-binding Protein dimerisation domain; Region: PBP_dimer; pfam03717
707186002112	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
707186002113	Penicillin binding protein transpeptidase domain; Region: Transpeptidase; cl17760
707186002114	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
707186002115	TPR motif; other site
707186002116	Tetratricopeptide repeat; Region: TPR_16; pfam13432
707186002117	binding surface
707186002118	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
707186002119	binding surface
707186002120	TPR motif; other site
707186002121	TPR repeat; Region: TPR_11; pfam13414
707186002122	TPR repeat; Region: TPR_11; pfam13414
707186002123	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
707186002124	binding surface
707186002125	TPR motif; other site
707186002126	TPR repeat; Region: TPR_11; pfam13414
707186002127	cysteine desulfurase activator complex subunit SufB; Provisional; Region: PRK11814
707186002128	putative ABC transporter; Region: ycf24; CHL00085
707186002129	FeS assembly ATPase SufC; Region: sufC; TIGR01978
707186002130	ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Region: ABC_FeS_Assembly; cd03217
707186002131	Walker A/P-loop; other site
707186002132	ATP binding site [chemical binding]; other site
707186002133	Q-loop/lid; other site
707186002134	ABC transporter signature motif; other site
707186002135	Walker B; other site
707186002136	D-loop; other site
707186002137	H-loop/switch region; other site
707186002138	Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones]; Region: SufB; COG0719
707186002139	FeS assembly protein SufD; Region: sufD; TIGR01981
707186002140	Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones]; Region: csdA; COG0520
707186002141	Cysteine desulfurase (SufS)-like. This family belongs to the pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to cysteine desulfurase (SufS) and selenocysteine lyase. SufS...; Region: SufS_like; cd06453
707186002142	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
707186002143	catalytic residue [active]
707186002144	ParB/RepB/Spo0J family partition protein; Region: parB_part; TIGR00180
707186002145	ParB-like nuclease domain; Region: ParBc; pfam02195
707186002146	KorB domain; Region: KorB; pfam08535
707186002147	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
707186002148	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppF; COG1124
707186002149	Walker A/P-loop; other site
707186002150	ATP binding site [chemical binding]; other site
707186002151	Q-loop/lid; other site
707186002152	ABC transporter signature motif; other site
707186002153	Walker B; other site
707186002154	D-loop; other site
707186002155	H-loop/switch region; other site
707186002156	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
707186002157	ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism]; Region: DppD; COG0444
707186002158	ATP-binding cassette domain of nickel/oligopeptides specific transporters; Region: ABC_NikE_OppD_transporters; cd03257
707186002159	Walker A/P-loop; other site
707186002160	ATP binding site [chemical binding]; other site
707186002161	Q-loop/lid; other site
707186002162	ABC transporter signature motif; other site
707186002163	Walker B; other site
707186002164	D-loop; other site
707186002165	H-loop/switch region; other site
707186002166	Oligopeptide/dipeptide transporter, C-terminal region; Region: oligo_HPY; cl07097
707186002167	Protein of unknown function DUF47; Region: PhoU_div; pfam01865
707186002168	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
707186002169	Phosphate/sulphate permeases [Inorganic ion transport and metabolism]; Region: PitA; COG0306
707186002170	Phosphoglycerate kinase; Region: PGK; pfam00162
707186002171	Phosphoglycerate kinase (PGK) is a monomeric enzyme which catalyzes the transfer of the high-energy phosphate group of 1,3-bisphosphoglycerate to ADP, forming ATP and 3-phosphoglycerate. This reaction represents the first of the two substrate-level...; Region: Phosphoglycerate_kinase; cd00318
707186002172	substrate binding site [chemical binding]; other site
707186002173	hinge regions; other site
707186002174	ADP binding site [chemical binding]; other site
707186002175	catalytic site [active]
707186002176	Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair]; Region: Nth; COG0177
707186002177	endonuclease III; includes endonuclease III (DNA-(apurinic or apyrimidinic site) lyase), alkylbase DNA glycosidases (Alka-family) and other DNA glycosidases; Region: ENDO3c; cd00056
707186002178	minor groove reading motif; other site
707186002179	helix-hairpin-helix signature motif; other site
707186002180	substrate binding pocket [chemical binding]; other site
707186002181	active site
707186002182	Predicted GTPase [General function prediction only]; Region: ThdF; COG0486
707186002183	GTP-binding protein TrmE N-terminus; Region: TrmE_N; pfam10396
707186002184	trmE is a tRNA modification GTPase; Region: trmE; cd04164
707186002185	G1 box; other site
707186002186	GTP/Mg2+ binding site [chemical binding]; other site
707186002187	Switch I region; other site
707186002188	G2 box; other site
707186002189	Switch II region; other site
707186002190	G3 box; other site
707186002191	G4 box; other site
707186002192	G5 box; other site
707186002193	Catalytic cysteine-containing C-terminus of GTPase, MnmE; Region: GTPase_Cys_C; pfam12631
707186002194	phosphatidylserine decarboxylase; Provisional; Region: PRK00723
707186002195	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
707186002196	binding surface
707186002197	TPR motif; other site
707186002198	preprotein translocase subunit SecA; Reviewed; Region: secA; PRK12899
707186002199	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cl17251
707186002200	ATP binding site [chemical binding]; other site
707186002201	putative Mg++ binding site [ion binding]; other site
707186002202	SecA preprotein cross-linking domain; Region: SecA_PP_bind; smart00958
707186002203	Predicted GTPases [General function prediction only]; Region: COG1160
707186002204	EngA1 GTPase contains the first domain of EngA; Region: EngA1; cd01894
707186002205	G1 box; other site
707186002206	GTP/Mg2+ binding site [chemical binding]; other site
707186002207	Switch I region; other site
707186002208	G2 box; other site
707186002209	Switch II region; other site
707186002210	G3 box; other site
707186002211	G4 box; other site
707186002212	G5 box; other site
707186002213	EngA2 GTPase contains the second domain of EngA; Region: EngA2; cd01895
707186002214	G1 box; other site
707186002215	GTP/Mg2+ binding site [chemical binding]; other site
707186002216	Switch I region; other site
707186002217	G2 box; other site
707186002218	G3 box; other site
707186002219	Switch II region; other site
707186002220	G4 box; other site
707186002221	G5 box; other site
707186002222	tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis]; Region: PcnB; COG0617
707186002223	Nucleotidyltransferase (NT) domain of ClassII CCA-adding enzymes; Region: NT_ClassII-CCAase; cd05398
707186002224	active site
707186002225	NTP binding site [chemical binding]; other site
707186002226	metal binding triad [ion binding]; metal-binding site
707186002227	Probable RNA and SrmB- binding site of polymerase A; Region: PolyA_pol_RNAbd; pfam12627
707186002228	ATP-dependent protease ATP-binding subunit ClpX; Provisional; Region: clpX; PRK05342
707186002229	ClpX C4-type zinc finger; Region: zf-C4_ClpX; smart00994
707186002230	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707186002231	Walker A motif; other site
707186002232	ATP binding site [chemical binding]; other site
707186002233	Walker B motif; other site
707186002234	arginine finger; other site
707186002235	C-terminal, D2-small domain, of ClpB protein; Region: ClpB_D2-small; smart01086
707186002236	Protease subunit of ATP-dependent Clp proteases [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion]; Region: ClpP; COG0740
707186002237	Caseinolytic protease (ClpP) is an ATP-dependent, highly conserved serine protease; Region: S14_ClpP_2; cd07017
707186002238	oligomer interface [polypeptide binding]; other site
707186002239	active site residues [active]
707186002240	FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) [Posttranslational modification, protein turnover, chaperones]; Region: Tig; COG0544
707186002241	Bacterial trigger factor protein (TF) C-terminus; Region: Trigger_C; pfam05698
707186002242	Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair]; Region: HepA; COG0553
707186002243	Bacterial SNF2 helicase associated; Region: SNF2_assoc; pfam08455
707186002244	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
707186002245	ATP binding site [chemical binding]; other site
707186002246	putative Mg++ binding site [ion binding]; other site
707186002247	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
707186002248	nucleotide binding region [chemical binding]; other site
707186002249	ATP-binding site [chemical binding]; other site
707186002250	rod shape-determining protein MreB; Provisional; Region: PRK13927
707186002251	MreB and similar proteins; Region: MreB_like; cd10225
707186002252	nucleotide binding site [chemical binding]; other site
707186002253	Mg binding site [ion binding]; other site
707186002254	putative protofilament interaction site [polypeptide binding]; other site
707186002255	RodZ interaction site [polypeptide binding]; other site
707186002256	Phosphoenolpyruvate carboxykinase (PEPCK), a critical gluconeogenic enzyme, catalyzes the first committed step in the diversion of tricarboxylic acid cycle intermediates toward gluconeogenesis. It catalyzes the reversible decarboxylation and...; Region: PEPCK_GTP; cd00819
707186002257	active site
707186002258	substrate-binding site [chemical binding]; other site
707186002259	metal-binding site [ion binding]
707186002260	GTP binding site [chemical binding]; other site
707186002261	Effector from type III secretion system; Region: Effector_1; pfam04518
707186002262	Effector from type III secretion system; Region: Effector_1; pfam04518
707186002263	Chlamydia major outer membrane protein; Region: Chlam_OMP; pfam01308
707186002264	Glycerol-3-phosphate dehydrogenase [Energy production and conversion]; Region: GpsA; COG0240
707186002265	NAD-dependent glycerol-3-phosphate dehydrogenase N-terminus; Region: NAD_Gly3P_dh_N; pfam01210
707186002266	NAD-dependent glycerol-3-phosphate dehydrogenase C-terminus; Region: NAD_Gly3P_dh_C; pfam07479
707186002267	UDP-glucose pyrophosphorylase [Carbohydrate transport and metabolism]; Region: COG4284
707186002268	Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold; Region: Glyco_tranf_GTA_type; cl11394
707186002269	active site
707186002270	sensor histidine kinase DpiB; Provisional; Region: dpiB; PRK15053
707186002271	type III secretion system ATPase; Validated; Region: PRK05922
707186002272	ATP synthase alpha/beta family, beta-barrel domain; Region: ATP-synt_ab_N; pfam02874
707186002273	RecA-like NTPases. This family includes the NTP binding domain of F1 and V1 H+ATPases, DnaB and related helicases as well as bacterial RecA and related eukaryotic and archaeal recombinases. This group also includes bacterial conjugation proteins and...; Region: RecA-like_NTPases; cl17233
707186002274	Walker A motif; other site
707186002275	ATP binding site [chemical binding]; other site
707186002276	Walker B motif; other site
707186002277	type III secretion system protein; Validated; Region: PRK05934
707186002278	Secretory protein of YscJ/FliF family; Region: YscJ_FliF; cl01907
707186002279	NifU homolog involved in Fe-S cluster formation [Energy production and conversion]; Region: IscU; COG0822
707186002280	Iron-sulfur cluster scaffold-like proteins; Region: IscU_like; cl00528
707186002281	active site
707186002282	Thioredoxin-like proteins and domains [Posttranslational modification, protein turnover, chaperones]; Region: COG0694
707186002283	Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism]; Region: NifS; COG1104
707186002284	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
707186002285	catalytic residue [active]
707186002286	Histidine phosphatase domain found in phosphoglycerate mutases and related proteins, mostly phosphatases; contains a His residue which is phosphorylated during the reaction; Region: HP_PGM_like; cd07067
707186002287	catalytic core [active]
707186002288	16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis]; Region: RsuA; COG1187
707186002289	S4/Hsp/ tRNA synthetase RNA-binding domain; The domain surface is populated by conserved, charged residues that define a likely RNA-binding site;  Found in stress proteins, ribosomal proteins and tRNA synthetases; This may imply a hitherto unrecognized...; Region: S4; cd00165
707186002290	RNA binding surface [nucleotide binding]; other site
707186002291	Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi); Region: PseudoU_synth; cl00130
707186002292	active site
707186002293	biotin--protein ligase; Provisional; Region: PRK05935
707186002294	Biotin-(acetyl-CoA carboxylase) ligase [Coenzyme metabolism]; Region: BirA; COG0340
707186002295	Bacterial cell division membrane protein [Cell division and chromosome partitioning]; Region: FtsW; COG0772
707186002296	heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase; Region: ATPase-IB2_Cd; TIGR01512
707186002297	E1-E2 ATPase; Region: E1-E2_ATPase; pfam00122
707186002298	Haloacid dehalogenase-like hydrolases. The haloacid dehalogenase-like (HAD) superfamily includes L-2-haloacid dehalogenase, epoxide hydrolase, phosphoserine phosphatase, phosphomannomutase, phosphoglycolate phosphatase, P-type ATPase, and many others; Region: HAD_like; cd01427
707186002299	motif II; other site
707186002300	CCC1-related protein family; Region: CCC1_like_1; cd02437
707186002301	seryl-tRNA synthetase; Provisional; Region: PRK05431
707186002302	Seryl-tRNA synthetase N-terminal domain; Region: Seryl_tRNA_N; pfam02403
707186002303	Seryl-tRNA synthetase (SerRS) class II core catalytic domain. SerRS is responsible for the attachment of serine to the 3' OH group of ribose of the appropriate tRNA. This domain It is primarily responsible for ATP-dependent formation of the enzyme...; Region: SerRS_core; cd00770
707186002304	dimer interface [polypeptide binding]; other site
707186002305	active site
707186002306	motif 1; other site
707186002307	motif 2; other site
707186002308	motif 3; other site
707186002309	riboflavin biosynthesis protein RibD; Region: eubact_ribD; TIGR00326
707186002310	Riboflavin-specific deaminase. Riboflavin biosynthesis protein RibD (Diaminohydroxyphosphoribosylaminopyrimidine deaminase) catalyzes the deamination of 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate, which is an intermediate step in the...; Region: Riboflavin_deaminase-reductase; cd01284
707186002311	catalytic motif [active]
707186002312	Zn binding site [ion binding]; other site
707186002313	RibD C-terminal domain; Region: RibD_C; pfam01872
707186002314	bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein; Provisional; Region: PRK09311
707186002315	3,4-dihydroxy-2-butanone 4-phosphate synthase; Region: DHBP_synthase; pfam00926
707186002316	GTP cyclohydrolase II (RibA).  GTP cyclohydrolase II catalyzes the conversion of GTP to 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5' phosphate, formate, pyrophosphate (APy), and GMP in the biosynthetic pathway of riboflavin. Riboflavin is the...; Region: GTP_cyclohydro2; cd00641
707186002317	dimerization interface [polypeptide binding]; other site
707186002318	active site
707186002319	lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, LS), catalyzes the penultimate step in the biosynthesis of riboflavin (vitamin B2); type-I; Region: Lumazine_synthase-I; cd09209
707186002320	homopentamer interface [polypeptide binding]; other site
707186002321	active site
707186002322	Na+/alanine symporter [Amino acid transport and metabolism]; Region: AlsT; COG1115
707186002323	Sodium:alanine symporter family; Region: Na_Ala_symp; cl00548
707186002324	PhosphatidylEthanolamine-Binding Protein (PEBP) domain present in bacteria and archaea; Region: PEBP_bact_arch; cd00865
707186002325	substrate binding site [chemical binding]; other site
707186002326	Proteins containing SET domain [General function prediction only]; Region: COG2940
707186002327	SET (Su(var)3-9, Enhancer-of-zeste, Trithorax) domain; Region: SET; smart00317
707186002328	Metal-dependent hydrolases of the beta-lactamase superfamily I [General function prediction only]; Region: PhnP; COG1235
707186002329	Domain of unknown function (DUF4117); Region: DUF4117; pfam13491
707186002330	DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning]; Region: FtsK; COG1674
707186002331	FtsK/SpoIIIE family; Region: FtsK_SpoIIIE; pfam01580
707186002332	Ftsk gamma domain; Region: Ftsk_gamma; pfam09397
707186002333	Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF [Energy production and conversion]; Region: NqrF; COG2871
707186002334	2Fe-2S iron-sulfur cluster binding domain. Iron-sulfur proteins play an important role in electron transfer processes and in various enzymatic reactions. The family includes plant and algal ferredoxins, which act as electron carriers in photosynthesis...; Region: fer2; cd00207
707186002335	catalytic loop [active]
707186002336	iron binding site [ion binding]; other site
707186002337	Na+-translocating NADH:quinone oxidoreductase (Na+-NQR) FAD/NADH binding domain. (Na+-NQR) provides a means of storing redox reaction energy via the transmembrane translocation of Na2+ ions. The C-terminal domain resembles ferredoxin:NADP+ oxidoreductase; Region: NADH_quinone_reductase; cd06188
707186002338	FAD binding pocket [chemical binding]; other site
707186002339	FAD binding motif [chemical binding]; other site
707186002340	phosphate binding motif [ion binding]; other site
707186002341	beta-alpha-beta structure motif; other site
707186002342	NAD binding pocket [chemical binding]; other site
707186002343	preprotein translocase, YajC subunit; Region: yajC; TIGR00739
707186002344	tRNA (uracil-5-)-methyltransferase; Validated; Region: PRK05031
707186002345	S-adenosylmethionine-dependent methyltransferases (SAM or AdoMet-MTase), class I;  AdoMet-MTases are enzymes that use S-adenosyl-L-methionine (SAM or AdoMet) as a substrate for methyltransfer, creating the product S-adenosyl-L-homocysteine (AdoHcy); Region: AdoMet_MTases; cd02440
707186002346	S-adenosylmethionine binding site [chemical binding]; other site
707186002347	Histone H1-like protein Hc1; Region: Hc1; pfam07432
707186002348	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
707186002349	binding surface
707186002350	TPR motif; other site
707186002351	Tetratricopeptide repeat; Region: TPR_12; pfam13424
707186002352	protoporphyrinogen oxidase; Reviewed; Region: PRK11883
707186002353	NAD(P)-binding Rossmann-like domain; Region: NAD_binding_8; pfam13450
707186002354	coproporphyrinogen III oxidase; Provisional; Region: PRK09249
707186002355	HemN C-terminal domain; Region: HemN_C; pfam06969
707186002356	Uroporphyrinogen decarboxylase (URO-D) is a dimeric cytosolic enzyme that decarboxylates the four acetate side chains of uroporphyrinogen III (uro-III) to create coproporphyrinogen III, without requiring any prosthetic groups or cofactors. This reaction...; Region: URO-D; cd00717
707186002357	substrate binding site [chemical binding]; other site
707186002358	active site
707186002359	Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription]; Region: Mfd; COG1197
707186002360	CarD-like/TRCF domain; Region: CarD_CdnL_TRCF; pfam02559
707186002361	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
707186002362	ATP binding site [chemical binding]; other site
707186002363	putative Mg++ binding site [ion binding]; other site
707186002364	Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may...; Region: HELICc; cd00079
707186002365	nucleotide binding region [chemical binding]; other site
707186002366	ATP-binding site [chemical binding]; other site
707186002367	TRCF domain; Region: TRCF; pfam03461
707186002368	alanyl-tRNA synthetase; Reviewed; Region: alaS; PRK00252
707186002369	Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent...; Region: AlaRS_core; cd00673
707186002370	motif 1; other site
707186002371	active site
707186002372	motif 2; other site
707186002373	motif 3; other site
707186002374	Threonyl and Alanyl tRNA synthetase second additional domain; Region: tRNA_SAD; pfam07973
707186002375	DHHA1 domain; Region: DHHA1; pfam02272
707186002376	Transketolase [Carbohydrate transport and metabolism]; Region: TktA; COG0021
707186002377	Thiamine pyrophosphate (TPP) family, Transketolase (TK) subfamily, TPP-binding module; TK catalyzes the transfer of a two-carbon unit from ketose phosphates to aldose phosphates. In heterotrophic organisms, TK provides a link between glycolysis and the...; Region: TPP_TK; cd02012
707186002378	TPP-binding site [chemical binding]; other site
707186002379	dimer interface [polypeptide binding]; other site
707186002380	Pyrimidine (PYR) binding domain of 1-deoxy-D-xylulose-5-phosphate synthase (DXS), transketolase (TK), and related proteins; Region: TPP_PYR_DXS_TK_like; cd07033
707186002381	PYR/PP interface [polypeptide binding]; other site
707186002382	dimer interface [polypeptide binding]; other site
707186002383	TPP binding site [chemical binding]; other site
707186002384	Transketolase, C-terminal domain; Region: Transketolase_C; pfam02780
707186002385	AMP nucleosidase, putative; Region: AMN-like; TIGR01721
707186002386	elongation factor P; Validated; Region: PRK00529
707186002387	Elongation factor P (EF-P) KOW-like domain; Region: EFP_N; pfam08207
707186002388	S1_EF-P_repeat_1: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_1; cd04470
707186002389	RNA binding site [nucleotide binding]; other site
707186002390	S1_EF-P_repeat_2: Translation elongation factor P (EF-P), S1-like RNA-binding domain, repeat 1. EF-P stimulates the peptidyltransferase activity in the prokaryotic 70S ribosome. EF-P enhances the synthesis of certain dipeptides with...; Region: S1_EF-P_repeat_2; cd05794
707186002391	RNA binding site [nucleotide binding]; other site
707186002392	Calcineurin-like phosphoesterase; Region: Metallophos; pfam00149
707186002393	Bacillus subtilis YydB and related proteins, metallophosphatase domain; Region: MPP_YydB; cd07400
707186002394	putative active site [active]
707186002395	putative metal binding site [ion binding]; other site
707186002396	metallophosphatase superfamily, metallophosphatase domain; Region: MPP_superfamily; cl13995
707186002397	active site
707186002398	metal binding site [ion binding]; metal-binding site
707186002399	Chaperonin GroEL (HSP60 family) [Posttranslational modification, protein turnover, chaperones]; Region: GroL; COG0459
707186002400	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
707186002401	UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Region: murF; TIGR01143
707186002402	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
707186002403	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
707186002404	phospho-N-acetylmuramoyl-pentapeptide-transferase; Provisional; Region: mraY; PRK00108
707186002405	Phospho-N-acetylmuramoyl-pentapeptide-transferase (mraY) is an enzyme responsible for the formation of the first lipid intermediate in the synthesis of bacterial cell wall peptidoglycan. It catalyzes the formation of...; Region: GT_MraY; cd06852
707186002406	Mg++ binding site [ion binding]; other site
707186002407	putative catalytic motif [active]
707186002408	putative substrate binding site [chemical binding]; other site
707186002409	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase; Provisional; Region: murD; PRK00683
707186002410	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
707186002411	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
707186002412	FOG: LysM repeat [Cell envelope biogenesis, outer membrane]; Region: LytE; COG1388
707186002413	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
707186002414	Lysine Motif is a small domain involved in binding peptidoglycan; Region: LysM; cd00118
707186002415	cell division protein FtsW; Region: ftsW; TIGR02614
707186002416	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; Region: murG; TIGR01133
707186002417	MurG is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide...; Region: GT1_MurG; cd03785
707186002418	active site
707186002419	homodimer interface [polypeptide binding]; other site
707186002420	bifunctional D-alanyl-alanine synthetase A/UDP-N-acetylmuramate--L-alanine ligase; Provisional; Region: PRK14573
707186002421	Mur ligase family, catalytic domain; Region: Mur_ligase; pfam01225
707186002422	Mur ligase middle domain; Region: Mur_ligase_M; pfam08245
707186002423	Mur ligase family, glutamate ligase domain; Region: Mur_ligase_C; pfam02875
707186002424	D-ala D-ala ligase N-terminus; Region: Dala_Dala_lig_N; pfam01820
707186002425	D-ala D-ala ligase C-terminus; Region: Dala_Dala_lig_C; pfam07478
707186002426	Predicted RNA-binding protein (contains KH domain) [General function prediction only]; Region: COG1837
707186002427	KH-II  (K homology RNA-binding domain, type II). KH binds single-stranded RNA or DNA. It is found in a wide variety of proteins including ribosomal proteins  (e.g. ribosomal protein S3), transcription factors (e.g. NusA_K), and post-transcriptional...; Region: KH-II; cd02409
707186002428	G-X-X-G motif; other site
707186002429	Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation; Region: STAS_anti-anti-sigma_factors; cd07043
707186002430	anti sigma factor interaction site; other site
707186002431	regulatory phosphorylation site [posttranslational modification]; other site
707186002432	tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed; Region: miaA; PRK00091
707186002433	tRNA delta(2)-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]; Region: MiaA; COG0324
707186002434	hypothetical protein; Provisional; Region: PRK05927
707186002435	Radical SAM superfamily. Enzymes of this family generate radicals by combining a 4Fe-4S cluster and S-adenosylmethionine (SAM) in close proximity. They are characterized by a conserved CxxxCxxC motif, which coordinates the conserved iron-sulfur cluster; Region: Radical_SAM; cl15377
707186002436	FeS/SAM binding site; other site
707186002437	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
707186002438	Uncharacterized homolog of plant Iojap protein [Function unknown]; Region: COG0799
707186002439	3-oxoacyl-(acyl carrier protein) synthase II; Reviewed; Region: PRK06333
707186002440	Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen...; Region: KAS_I_II; cd00834
707186002441	dimer interface [polypeptide binding]; other site
707186002442	active site
707186002443	Diadenosine tetraphosphate (Ap4A) hydrolase is a member of the Nudix hydrolase superfamily. Ap4A hydrolases are well represented in a variety of prokaryotic and eukaryotic organisms. Phylogenetic analysis reveals two distinct subgroups where plant...; Region: Ap4A_hydrolase_human_like; cd03428
707186002444	active site
707186002445	Ap4A binding cleft/pocket [chemical binding]; other site
707186002446	P4 phosphate binding site; other site
707186002447	nudix motif; other site
707186002448	putative P2/P3 phosphate binding site [ion binding]; other site
707186002449	Inorganic pyrophosphatase. These enzymes hydrolyze inorganic pyrophosphate (PPi) to two molecules of orthophosphates (Pi). The reaction requires bivalent cations. The enzymes in general exist as homooligomers; Region: pyrophosphatase; cd00412
707186002450	dimer interface [polypeptide binding]; other site
707186002451	substrate binding site [chemical binding]; other site
707186002452	metal binding sites [ion binding]; metal-binding site
707186002453	Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism]; Region: GdhA; COG0334
707186002454	Glu/Leu/Phe/Val dehydrogenase, dimerisation domain; Region: ELFV_dehydrog_N; pfam02812
707186002455	NAD(P) binding domain of leucine dehydrogenase, phenylalanine dehydrogenase, and valine dehydrogenase; Region: NAD_bind_Leu_Phe_Val_DH; cd01075
707186002456	NAD binding site [chemical binding]; other site
707186002457	Phe binding site; other site
707186002458	PAP-phosphatase_like domains. PAP-phosphatase is a member of the inositol monophosphatase family, and catalyses the hydrolysis of 3'-phosphoadenosine-5'-phosphate (PAP) to AMP. In Saccharomyces cerevisiae, HAL2 (MET22) is involved in methionine...; Region: PAP_phosphatase; cd01517
707186002459	Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism]; Region: SuhB; COG0483
707186002460	active site
707186002461	putative lithium-binding site [ion binding]; other site
707186002462	substrate binding site [chemical binding]; other site
707186002463	1-acyl-sn-glycerol-3-phosphate acyltransferase [Lipid metabolism]; Region: PlsC; COG0204
707186002464	Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like; Region: LPLAT_AGPAT-like; cd07989
707186002465	putative acyl-acceptor binding pocket; other site
707186002466	long chain fatty acid--[acyl-carrier-protein] ligase; Validated; Region: PRK06334
707186002467	Adenylate forming domain, Class I; Region: AFD_class_I; cl17068
707186002468	acyl-activating enzyme (AAE) consensus motif; other site
707186002469	AMP binding site [chemical binding]; other site
707186002470	active site
707186002471	CoA binding site [chemical binding]; other site
707186002472	8-amino-7-oxononanoate synthase; Provisional; Region: PRK05937
707186002473	Aminotransferase class I and II; Region: Aminotran_1_2; pfam00155
707186002474	pyridoxal 5'-phosphate binding pocket [chemical binding]; other site
707186002475	catalytic residue [active]
707186002476	Primosomal protein N' (replication factor Y) - superfamily II helicase [DNA replication, recombination, and repair]; Region: PriA; COG1198
707186002477	DEAD-like helicases superfamily. A diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region; Region: DEXDc; cd00046
707186002478	ATP binding site [chemical binding]; other site
707186002479	putative Mg++ binding site [ion binding]; other site
707186002480	helicase superfamily c-terminal domain; Region: HELICc; smart00490
707186002481	Thioredoxin-like domain; Region: Thioredoxin_2; pfam13098
707186002482	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
707186002483	lysyl-tRNA synthetase; Reviewed; Region: lysS; PRK00484
707186002484	LysRS_N: N-terminal, anticodon recognition domain of lysyl-tRNA synthetases (LysRS). These enzymes are homodimeric class 2b aminoacyl-tRNA synthetases (aaRSs). This domain is a beta-barrel domain (OB fold) involved in binding the tRNA anticodon stem-loop; Region: LysRS_N; cd04322
707186002485	dimer interface [polypeptide binding]; other site
707186002486	putative anticodon binding site; other site
707186002487	Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA.   PheRS is an exception in that it...; Region: class_II_aaRS-like_core; cl00268
707186002488	motif 1; other site
707186002489	dimer interface [polypeptide binding]; other site
707186002490	active site
707186002491	motif 2; other site
707186002492	motif 3; other site
707186002493	cysteinyl-tRNA synthetase; Validated; Region: cysS; PRK00260
707186002494	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
707186002495	active site
707186002496	HIGH motif; other site
707186002497	catalytic core domain of cysteinyl tRNA synthetase; Region: CysRS_core; cd00672
707186002498	KMSKS motif; other site
707186002499	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
707186002500	tRNA binding surface [nucleotide binding]; other site
707186002501	anticodon binding site; other site
707186002502	Thioredoxin-like; Region: Thioredoxin_7; pfam13899
707186002503	Thioredoxin-like; Region: Thioredoxin_8; pfam13905
707186002504	ribonuclease P; Reviewed; Region: rnpA; PRK00730
707186002505	50S ribosomal protein L36; Validated; Region: rpmJ; PRK00831
707186002506	30S ribosomal protein S14; Reviewed; Region: rpsN; PRK08881
707186002507	Domain of unknown function (DUF4339); Region: DUF4339; pfam14237
707186002508	Uncharacterized protein conserved in bacteria [Function unknown]; Region: COG1302
707186002509	excinuclease ABC subunit C; Validated; Region: uvrC; PRK00558
707186002510	Catalytic GIY-YIG domain of nucleotide excision repair endonucleases UvrC, Cho, and similar proteins; Region: GIY-YIG_UvrC_Cho; cd10434
707186002511	GIY-YIG motif/motif A; other site
707186002512	active site
707186002513	catalytic site [active]
707186002514	putative DNA binding site [nucleotide binding]; other site
707186002515	metal binding site [ion binding]; metal-binding site
707186002516	UvrC Helix-hairpin-helix N-terminal; Region: UvrC_HhH_N; pfam08459
707186002517	DNA mismatch repair protein MutS; Provisional; Region: PRK05399
707186002518	MutS domain I; Region: MutS_I; pfam01624
707186002519	MutS domain II; Region: MutS_II; pfam05188
707186002520	MutS domain III; Region: MutS_III; pfam05192
707186002521	ATP-binding cassette domain of MutS1 homolog; Region: ABC_MutS1; cd03284
707186002522	Walker A/P-loop; other site
707186002523	ATP binding site [chemical binding]; other site
707186002524	Q-loop/lid; other site
707186002525	ABC transporter signature motif; other site
707186002526	Walker B; other site
707186002527	D-loop; other site
707186002528	H-loop/switch region; other site
707186002529	DNA primase; Validated; Region: dnaG; PRK05667
707186002530	CHC2 zinc finger; Region: zf-CHC2; pfam01807
707186002531	DNA primase catalytic core, N-terminal domain; Region: Toprim_N; pfam08275
707186002532	TOPRIM_DnaG_primases: The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of proteins similar to Escherichia coli DnaG. Primases synthesize RNA primers for the initiation of DNA replication. DnaG...; Region: TOPRIM_DnaG_primases; cd03364
707186002533	active site
707186002534	metal binding site [ion binding]; metal-binding site
707186002535	interdomain interaction site; other site
707186002536	glycyl-tRNA synthetase; Provisional; Region: PRK14908
707186002537	Class II Glycyl-tRNA synthetase (GlyRS) alpha subunit core catalytic domain. GlyRS functions as a homodimer in eukaryotes, archaea and some bacteria and as a heterotetramer in the remainder of prokaryotes and in arabidopsis. It is responsible for the...; Region: GlyRS_alpha_core; cd00733
707186002538	dimer interface [polypeptide binding]; other site
707186002539	motif 1; other site
707186002540	active site
707186002541	motif 2; other site
707186002542	motif 3; other site
707186002543	Anticodon-binding domain of class Ia aminoacyl tRNA synthetases and similar domains; Region: Anticodon_Ia_like; cl12020
707186002544	Phosphatidylglycerophosphate synthase [Lipid metabolism]; Region: PgsA; COG0558
707186002545	glycogen synthase; Provisional; Region: glgA; PRK00654
707186002546	This family is most closely related to the GT1 family of glycosyltransferases. Glycogen synthase catalyzes the formation and elongation of the alpha-1,4-glucose backbone using ADP-glucose, the second and key step of glycogen biosynthesis. This family...; Region: GT1_Glycogen_synthase_DULL1_like; cd03791
707186002547	ADP-binding pocket [chemical binding]; other site
707186002548	homodimer interface [polypeptide binding]; other site
707186002549	Ribosomal L25/TL5/CTC N-terminal 5S rRNA binding domain; Region: Ribosomal_L25_TL5_CTC; cd00495
707186002550	ribosomal protein L25, Ctc-form; Region: ctc_TL5; TIGR00731
707186002551	5S rRNA interface [nucleotide binding]; other site
707186002552	CTC domain interface [polypeptide binding]; other site
707186002553	L16 interface [polypeptide binding]; other site
707186002554	Peptidyl-tRNA hydrolase (PTH) is a monomeric protein that cleaves the ester bond linking the nascent peptide and tRNA when peptidyl-tRNA is released prematurely from the ribosome. This ensures the recycling of peptidyl-tRNAs into tRNAs produced through...; Region: PTH; cd00462
707186002555	putative active site [active]
707186002556	catalytic residue [active]
707186002557	Ribosomal protein S6 [Translation, ribosomal structure and biogenesis]; Region: RpsF; COG0360
707186002558	30S ribosomal protein S18; Reviewed; Region: rpsR; PRK00391
707186002559	Ribosomal protein L9 [Translation, ribosomal structure and biogenesis]; Region: RplI; COG0359
707186002560	Ribosomal protein L9, N-terminal domain; Region: Ribosomal_L9_N; pfam01281
707186002561	Ribosomal protein L9, C-terminal domain; Region: Ribosomal_L9_C; pfam03948
707186002562	4-diphosphocytidyl-2-C-methyl-D-erythritol kinase; Provisional; Region: PRK00650
707186002563	Protein of unknown function (DUF1504); Region: DUF1504; pfam07399
707186002564	Secreted/periplasmic Zn-dependent peptidases, insulinase-like [Posttranslational modification, protein turnover, chaperones]; Region: Ptr; COG1025
707186002565	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
707186002566	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
707186002567	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
707186002568	Lysophospholipid acyltransferases (LPLATs) of glycerophospholipid biosynthesis; Region: LPLAT; cl17185
707186002569	putative acyl-acceptor binding pocket; other site
707186002570	ribonuclease, Rne/Rng family; Region: RNaseEG; TIGR00757
707186002571	S1_RNase_E: RNase E and RNase G, S1-like RNA-binding domain. RNase E is an essential endoribonuclease in the processing and degradation of RNA. In addition to its role in mRNA degradation, RNase E has also been implicated in the processing of rRNA, and...; Region: S1_RNase_E; cd04453
707186002572	homodimer interface [polypeptide binding]; other site
707186002573	oligonucleotide binding site [chemical binding]; other site
707186002574	50S ribosomal protein L32; Reviewed; Region: rpmF; PRK12286
707186002575	putative glycerol-3-phosphate acyltransferase PlsX; Provisional; Region: PRK13846
707186002576	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707186002577	Autotransporter beta-domain; Region: Autotransporter; pfam03797
707186002578	YtxH-like protein; Region: YtxH; cl02079
707186002579	phosphoglucosamine mutase; Provisional; Region: glmM; PRK14314
707186002580	GlmM is a bacterial phosphoglucosamine mutase (PNGM) that belongs to the alpha-D-phosphohexomutase superfamily. It is required for the interconversion of glucosamine-6-phosphate and glucosamine-1-phosphate in the biosynthetic pathway of...; Region: GlmM; cd05802
707186002581	active site
707186002582	substrate binding site [chemical binding]; other site
707186002583	metal binding site [ion binding]; metal-binding site
707186002584	glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Region: glmS; TIGR01135
707186002585	Glutamine amidotransferases class-II (Gn-AT)_GFAT-type. This domain is found at the N-terminus of glucosamine-6P synthase (GlmS, or GFAT in humans).  The glutaminase domain catalyzes amide nitrogen transfer from glutamine to the appropriate substrate. In...; Region: GFAT; cd00714
707186002586	glutaminase active site [active]
707186002587	SIS (Sugar ISomerase) domain repeat 1 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_1; cd05008
707186002588	dimer interface [polypeptide binding]; other site
707186002589	active site
707186002590	SIS (Sugar ISomerase) domain repeat 2 found in Glucosamine 6-phosphate synthase (GlmS) and Glucosamine-6-phosphate deaminase (GlmD). The SIS domain is found in many phosphosugar isomerases and phosphosugar binding proteins. GlmS contains a N-terminal...; Region: SIS_GlmS_GlmD_2; cd05009
707186002591	dimer interface [polypeptide binding]; other site
707186002592	active site
707186002593	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; pfam03222
707186002594	aromatic amino acid transport protein; Region: araaP; TIGR00837
707186002595	Tryptophan/tyrosine permease family; Region: Trp_Tyr_perm; pfam03222
707186002596	aromatic amino acid transport protein; Region: araaP; TIGR00837
707186002597	Integral membrane protein, interacts with FtsH [General function prediction only]; Region: COG0670
707186002598	Bacterial BAX inhibitor (BI)-1/YccA-like proteins; Region: BI-1-like_bacterial; cd10432
707186002599	SRP54-type protein, helical bundle domain; Region: SRP54_N; pfam02881
707186002600	signal recognition particle-docking protein FtsY; Provisional; Region: PRK10416
707186002601	The Fer4_NifH superfamily contains a variety of proteins which share a common ATP-binding domain. Functionally, proteins in this superfamily use the energy from hydrolysis of NTP to transfer electron or ion; Region: Fer4_NifH; cl17203
707186002602	succinyl-CoA synthetase, beta subunit; Region: sucCoAbeta; TIGR01016
707186002603	ATP-grasp domain; Region: ATP-grasp_2; pfam08442
707186002604	CoA-ligase; Region: Ligase_CoA; pfam00549
707186002605	succinyl-CoA synthetase subunit alpha; Validated; Region: PRK05678
707186002606	CoA binding domain; Region: CoA_binding; smart00881
707186002607	CoA-ligase; Region: Ligase_CoA; pfam00549
707186002608	periplasmic serine protease, Do/DeqQ family; Region: degP_htrA_DO; TIGR02037
707186002609	Trypsin-like peptidase domain; Region: Trypsin_2; pfam13365
707186002610	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
707186002611	protein binding site [polypeptide binding]; other site
707186002612	PDZ domain of tryspin-like serine proteases, such as DegP/HtrA, which are oligomeric proteins involved in heat-shock response, chaperone function, and apoptosis. May be responsible for substrate recognition and/or binding, as most PDZ domains bind...; Region: PDZ_serine_protease; cd00987
707186002613	protein binding site [polypeptide binding]; other site
707186002614	Predicted Zn-dependent peptidases, insulinase-like [General function prediction only]; Region: COG1026
707186002615	Insulinase (Peptidase family M16); Region: Peptidase_M16; pfam00675
707186002616	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
707186002617	Peptidase M16C associated; Region: M16C_assoc; pfam08367
707186002618	Peptidase M16 inactive domain; Region: Peptidase_M16_C; pfam05193
707186002619	Predicted nuclease of restriction endonuclease-like fold, RmuC family [General function prediction only]; Region: COG1322
707186002620	RmuC family; Region: RmuC; pfam02646
707186002621	Phosphatidylserine synthase [Lipid metabolism]; Region: PssA; COG1183
707186002622	CDP-alcohol phosphatidyltransferase; Region: CDP-OH_P_transf; pfam01066
707186002623	ribonucleotide-diphosphate reductase subunit alpha; Provisional; Region: PRK12365
707186002624	ATP cone domain; Region: ATP-cone; pfam03477
707186002625	ATP cone domain; Region: ATP-cone; pfam03477
707186002626	Class I ribonucleotide reductase; Region: RNR_I; cd01679
707186002627	active site
707186002628	dimer interface [polypeptide binding]; other site
707186002629	catalytic residues [active]
707186002630	effector binding site; other site
707186002631	R2 peptide binding site; other site
707186002632	Ribonucleotide Reductase, R2/beta subunit, ferritin-like diiron-binding domain; Region: RNRR2; cd01049
707186002633	dimer interface [polypeptide binding]; other site
707186002634	putative radical transfer pathway; other site
707186002635	diiron center [ion binding]; other site
707186002636	tyrosyl radical; other site
707186002637	Putative methyltransferase; Region: Methyltransf_4; pfam02390
707186002638	Methyltransferase domain; Region: Methyltransf_18; pfam12847
707186002639	Putative rRNA methylase; Region: rRNA_methylase; pfam06962
707186002640	UDP-N-acetylenolpyruvoylglucosamine reductase; Provisional; Region: murB; PRK13905
707186002641	FAD binding domain; Region: FAD_binding_4; pfam01565
707186002642	UDP-N-acetylenolpyruvoylglucosamine reductase, C-terminal domain; Region: MurB_C; pfam02873
707186002643	Transcription termination factor NusB (N protein-Utilization Substance B). NusB plays a key role in the regulation of ribosomal RNA biosynthesis in eubacteria by modulating the efficiency of transcriptional antitermination. NusB along with other Nus...; Region: Terminator_NusB; cd00619
707186002644	putative RNA binding site [nucleotide binding]; other site
707186002645	translation initiation factor IF-3; Reviewed; Region: infC; PRK00028
707186002646	Translation initiation factor IF-3, N-terminal domain; Region: IF3_N; pfam05198
707186002647	Translation initiation factor IF-3, C-terminal domain; Region: IF3_C; pfam00707
707186002648	Ribosomal protein L35 [Translation, ribosomal structure and biogenesis]; Region: RpmI; COG0291
707186002649	Ribosomal protein L20; Region: Ribosomal_L20; cd07026
707186002650	23S rRNA binding site [nucleotide binding]; other site
707186002651	L21 binding site [polypeptide binding]; other site
707186002652	L13 binding site [polypeptide binding]; other site
707186002653	phenylalanyl-tRNA synthetase subunit alpha; Validated; Region: pheS; PRK00488
707186002654	Aminoacyl tRNA synthetase class II, N-terminal domain; Region: Phe_tRNA-synt_N; pfam02912
707186002655	Phenylalanyl-tRNA synthetase (PheRS) alpha chain catalytic core domain. PheRS belongs to class II aminoacyl-tRNA synthetases (aaRS) based upon its structure and the presence of three characteristic sequence motifs. This domain is primarily responsible...; Region: PheRS_alpha_core; cd00496
707186002656	motif 1; other site
707186002657	dimer interface [polypeptide binding]; other site
707186002658	active site
707186002659	motif 2; other site
707186002660	motif 3; other site
707186002661	potential protein location (hypothetical protein G11222_04480 [Chlamydia trachomatis G/11222]) that overlaps RNA (tRNA-S)
707186002662	Predicted permeases [General function prediction only]; Region: COG0795
707186002663	Predicted permeases [General function prediction only]; Region: COG0795
707186002664	Predicted permease YjgP/YjgQ family; Region: YjgP_YjgQ; pfam03739
707186002665	tRNA(Ile)-lysidine synthase MesJ [Cell cycle control, cell division, chromosome partitioning]; Region: MesJ; COG0037
707186002666	N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases...; Region: PP-ATPase; cd01992
707186002667	Ligand Binding Site [chemical binding]; other site
707186002668	ATP-dependent metalloprotease FtsH; Region: FtsH_fam; TIGR01241
707186002669	The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC; Region: AAA; cd00009
707186002670	Walker A motif; other site
707186002671	ATP binding site [chemical binding]; other site
707186002672	Walker B motif; other site
707186002673	arginine finger; other site
707186002674	Peptidase family M41; Region: Peptidase_M41; pfam01434
707186002675	polynucleotide phosphorylase/polyadenylase; Provisional; Region: PRK11824
707186002676	Polyribonucleotide nucleotidyltransferase, repeat 1; Region: RNase_PH_PNPase_1; cd11363
707186002677	RNase E interface [polypeptide binding]; other site
707186002678	trimer interface [polypeptide binding]; other site
707186002679	Polyribonucleotide nucleotidyltransferase, RNA binding domain; Region: PNPase; pfam03726
707186002680	Polyribonucleotide nucleotidyltransferase, repeat 2; Region: RNase_PH_PNPase_2; cd11364
707186002681	RNase E interface [polypeptide binding]; other site
707186002682	trimer interface [polypeptide binding]; other site
707186002683	active site
707186002684	Polynucleotide phosphorylase (PNPase) K homology RNA-binding domain (KH). PNPase is a polyribonucleotide nucleotidyl transferase that degrades mRNA in prokaryotes and plant chloroplasts. The C-terminal region of PNPase contains domains homologous to...; Region: PNPase_KH; cd02393
707186002685	putative nucleic acid binding region [nucleotide binding]; other site
707186002686	G-X-X-G motif; other site
707186002687	S1_PNPase: Polynucleotide phosphorylase (PNPase), ), S1-like RNA-binding domain. PNPase  is a polyribonucleotide nucleotidyl transferase that degrades mRNA. It is a trimeric multidomain protein. The C-terminus contains the S1 domain which binds ssRNA; Region: S1_PNPase; cd04472
707186002688	RNA binding site [nucleotide binding]; other site
707186002689	domain interface; other site
707186002690	Ribosomal protein S15 (prokaryotic)_S13 (eukaryotic) binds the central domain of 16S rRNA and is required for assembly of the small ribosomal subunit and for intersubunit association, thus representing a key element in the assembly of the whole ribosome; Region: Ribosomal_S15p_S13e; cd00353
707186002691	16S/18S rRNA binding site [nucleotide binding]; other site
707186002692	S13e-L30e interaction site [polypeptide binding]; other site
707186002693	25S rRNA binding site [nucleotide binding]; other site
707186002694	Nucleoside deaminases include adenosine, guanine and cytosine deaminases. These enzymes are Zn dependent and catalyze the deamination of nucleosides. The zinc ion in the active site plays a central role in the proposed catalytic mechanism, activating a...; Region: nucleoside_deaminase; cd01285
707186002695	nucleoside/Zn binding site; other site
707186002696	dimer interface [polypeptide binding]; other site
707186002697	catalytic motif [active]
707186002698	Protein of unknown function (DUF720); Region: DUF720; pfam05302
707186002699	Protein of unknown function (DUF720); Region: DUF720; pfam05302
707186002700	Protein of unknown function (DUF720); Region: DUF720; pfam05302
707186002701	Chromosome segregation ATPases [Cell division and chromosome partitioning]; Region: Smc; COG1196
707186002702	methionine aminopeptidase; Provisional; Region: PRK12318
707186002703	SEC-C motif; Region: SEC-C; pfam02810
707186002704	Methionine Aminopeptidase 1. E.C. 3.4.11.18. Also known as methionyl aminopeptidase and Peptidase M. Catalyzes release of N-terminal amino acids, preferentially methionine, from peptides and arylamides; Region: MetAP1; cd01086
707186002705	active site
707186002706	MarC family integral membrane protein; Region: MarC; pfam01914
707186002707	Multiple antibiotic transporter [Intracellular trafficking and secretion]; Region: MarC; COG2095
707186002708	ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism]; Region: TauC; COG0600
707186002709	Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and...; Region: TM_PBP2; cd06261
707186002710	dimer interface [polypeptide binding]; other site
707186002711	conserved gate region; other site
707186002712	putative PBP binding loops; other site
707186002713	ABC-ATPase subunit interface; other site
707186002714	NMT1/THI5 like; Region: NMT1; pfam09084
707186002715	fumarate hydratase, class II; Region: fumC_II; TIGR00979
707186002716	Class II fumarases; Region: Fumarase_classII; cd01362
707186002717	active site
707186002718	tetramer interface [polypeptide binding]; other site
707186002719	high affinity sulphate transporter 1; Region: sulP; TIGR00815
707186002720	Sulfate transporter N-terminal domain with GLY motif; Region: Sulfate_tra_GLY; pfam13792
707186002721	Sulfate transporter family; Region: Sulfate_transp; pfam00916
707186002722	Sulphate Transporter and Anti-Sigma factor antagonist domain of SulP-like sulfate transporters, plays a role in the function and regulation of the transport activity, proposed general NTP binding function; Region: STAS_SulP_like_sulfate_transporter; cd07042
707186002723	Na+/H+ antiporter, NhaD family; Region: NhaD; TIGR00775
707186002724	Na+/H+ antiporter NhaD and related arsenite permeases [Inorganic ion transport and metabolism]; Region: ArsB; COG1055
707186002725	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
707186002726	C-terminal processing peptidase family S41; Region: Peptidase_S41; cl02526
707186002727	Interphotoreceptor retinoid-binding protein; serine protease family S41; Region: Peptidase_S41_IRBP; cd07563
707186002728	active site triad [active]
707186002729	4-hydroxy-3-methylbut-2-enyl diphosphate reductase; Reviewed; Region: ispH; PRK01045
707186002730	LytB protein; Region: LYTB; pfam02401
707186002731	type III secretion low calcium response chaperone LcrH/SycD; Region: LcrH_SycD; TIGR02552
707186002732	Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]- X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi; Region: TPR; cd00189
707186002733	binding surface
707186002734	TPR motif; other site
707186002735	site-specific tyrosine recombinase XerD; Reviewed; Region: xerD; PRK00283
707186002736	DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine recombinases that share the same fold in their catalytic domain containing six conserved active site...; Region: DNA_BRE_C; cl00213
707186002737	active site
707186002738	DNA binding site [nucleotide binding]
707186002739	Int/Topo IB signature motif; other site
707186002740	glycogen branching enzyme; Provisional; Region: PRK05402
707186002741	N-terminal Early set domain associated with the catalytic domain of prokaryotic glycogen branching enzyme; Region: E_set_GBE_prok_N; cd02855
707186002742	Alpha amylase catalytic domain found in the Glycogen branching enzyme (also called 1,4-alpha-glucan branching enzyme); Region: AmyAc_Glg_BE; cd11322
707186002743	active site
707186002744	catalytic site [active]
707186002745	Alpha amylase, C-terminal all-beta domain; Region: Alpha-amylase_C; pfam02806
707186002746	Ulp1 protease family, C-terminal catalytic domain; Region: Peptidase_C48; cl17784
707186002747	Ulp1 protease family, C-terminal catalytic domain; Region: Peptidase_C48; cl17784
707186002748	Chlamydial polymorphic outer membrane protein repeat; Region: POMP_repeat; TIGR01376
707186002749	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707186002750	Autotransporter beta-domain; Region: Autotransporter; pfam03797
707186002751	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707186002752	Autotransporter beta-domain; Region: Autotransporter; pfam03797
707186002753	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707186002754	Autotransporter beta-domain; Region: Autotransporter; pfam03797
707186002755	Chlamydial polymorphic outer membrane protein repeat; Region: POMP_repeat; TIGR01376
707186002756	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707186002757	Autotransporter beta-domain; Region: Autotransporter; pfam03797
707186002758	Chlamydial polymorphic outer membrane protein repeat; Region: POMP_repeat; TIGR01376
707186002759	Chlamydial polymorphic outer membrane protein repeat; Region: POMP_repeat; TIGR01376
707186002760	Chlamydial polymorphic outer membrane protein repeat; Region: POMP_repeat; TIGR01376
707186002761	Chlamydia polymorphic membrane protein middle domain; Region: ChlamPMP_M; pfam07548
707186002762	Autotransporter beta-domain; Region: Autotransporter; pfam03797