-- dump date 20140618_204237 -- class Genbank::Feature -- table feature -- table main -- field 1 id -- field 2 type -- field 3 name -- field 4 contig -- field 5 start_pos -- field 6 end_pos -- field 7 strand -- field 8 description -- field 9 chrom_position -- field 10 organism -- field 11 GeneID -- header -- id type name contig start_pos end_pos strand description chrom_position organism GeneID 234826000001 SEQ_END SEQ_END NC_004842.2 1197687 1197687 DR NC_004842.2; contig end 1197687..1197687 Anaplasma marginale str. St. Maries YP_153445.1 CDS AM1359 NC_004842.2 1 1905 D hypothetical protein identified by Glimmer 2; hypothetical protein 1..1905 Anaplasma marginale str. St. Maries 3171015 YP_153446.1 CDS purE NC_004842.2 1862 2362 R COG0026 phosphoribosylaminoimidazole carboxylase (NCAIR synthetase); phosphoribosylaminoimidazole carboxylase catalytic subunit complement(1862..2362) Anaplasma marginale str. St. Maries 3171371 YP_153447.1 CDS AM002 NC_004842.2 2355 2957 R conserved hypothetical protein similar to ZP_00211153.1; hypothetical protein complement(2355..2957) Anaplasma marginale str. St. Maries 3171684 YP_153448.1 CDS rodA NC_004842.2 3113 4183 D COG0772 FtsW bacterial cell division membrane protein; similar to NP_220664.1; rod shape determining protein 3113..4183 Anaplasma marginale str. St. Maries 3171340 YP_153449.1 CDS AM006 NC_004842.2 4258 4554 D conserved family - DNA binding protein; hypothetical protein 4258..4554 Anaplasma marginale str. St. Maries 3171562 YP_153450.1 CDS AM007 NC_004842.2 4551 4925 D conserved family - transcriptional regulator; hypothetical protein 4551..4925 Anaplasma marginale str. St. Maries 3171137 YP_153451.1 CDS AM008 NC_004842.2 5187 6119 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(5187..6119) Anaplasma marginale str. St. Maries 3171867 YP_153452.1 CDS AM009 NC_004842.2 6209 6619 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(6209..6619) Anaplasma marginale str. St. Maries 3171817 YP_153453.1 CDS murC NC_004842.2 6921 7544 D COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes; open reading frame split domain with AM011; UDP-N-acetylmuramate-alanine ligase 6921..7544 Anaplasma marginale str. St. Maries 3171582 YP_153454.1 CDS murC NC_004842.2 7532 8368 D COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes; open reading frame split domain with AM010; UDP-N-acetylmuramate-alanine ligase 7532..8368 Anaplasma marginale str. St. Maries 3171005 YP_153455.1 CDS trpS NC_004842.2 8395 9384 R COG0180 trpS tryptophanyl-tRNA synthetase; tryptophanyl-tRNA synthetase complement(8395..9384) Anaplasma marginale str. St. Maries 3171357 YP_153456.1 CDS grpE NC_004842.2 9381 9875 R COG0576 GrpE molecular chaperone GrpE (heat shock protein); GRPE protein complement(9381..9875) Anaplasma marginale str. St. Maries 3171329 YP_153457.1 CDS ribD NC_004842.2 10097 11212 D COG0117 RibD pyrimidine deaminase; riboflavin biosynthesis protein 10097..11212 Anaplasma marginale str. St. Maries 3171598 YP_153458.1 CDS pyrG NC_004842.2 11486 13168 R CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase complement(11486..13168) Anaplasma marginale str. St. Maries 3171313 YP_153459.1 CDS secG NC_004842.2 13181 13510 R conserved hypothetical protein similar to ZP_00211144.1; preprotein translocase subunit SecG complement(13181..13510) Anaplasma marginale str. St. Maries 3171139 YP_153460.1 CDS AM020 NC_004842.2 13686 13946 D hypothetical protein identified by Glimmer 2; hypothetical protein 13686..13946 Anaplasma marginale str. St. Maries 3171666 YP_153461.1 CDS xerD NC_004842.2 13939 14877 D COG0582 XerC integrase; integrase/recombinase 13939..14877 Anaplasma marginale str. St. Maries 3170978 YP_153462.1 CDS phnL NC_004842.2 15075 15749 R COG1136 PhnL ABC-type transport systems involved in lipoprotein release, ATPase components; similar to NP_102951.1; ATP transporter ATP-binding protein complement(15075..15749) Anaplasma marginale str. St. Maries 3171442 YP_153463.1 CDS maeB NC_004842.2 16020 18272 D NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 16020..18272 Anaplasma marginale str. St. Maries 3171619 YP_153464.1 CDS AM025 NC_004842.2 18446 21166 D conserved family - exoprotein involved in heme utilization or adhesion; hypothetical protein 18446..21166 Anaplasma marginale str. St. Maries 3171915 YP_153465.1 CDS AM026 NC_004842.2 21386 22900 D subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; monovalent cation/H+ antiporter subunit D 21386..22900 Anaplasma marginale str. St. Maries 3171686 YP_153466.1 CDS AM027 NC_004842.2 22915 23301 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(22915..23301) Anaplasma marginale str. St. Maries 3171061 YP_153467.1 CDS orfX NC_004842.2 23496 23882 R other copies include: AM044, AM065, AM077, AM082 AM210, AM717, AM723, AM989, AM1061, AM1149 and AM1253; member of msp2 superfamily; hypothetical protein complement(23496..23882) Anaplasma marginale str. St. Maries 3171600 YP_153468.1 CDS orfY NC_004842.2 23955 24188 R other copies include: AM046, AM063, AM721, AM990 AM1059 and AM1251; member of msp2 superfamily; hypothetical protein complement(23955..24188) Anaplasma marginale str. St. Maries 3171579 YP_153469.1 CDS AM034 NC_004842.2 25004 27445 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(25004..27445) Anaplasma marginale str. St. Maries 3171715 YP_153470.1 CDS AM035 NC_004842.2 27643 27852 D conserved hypothetical protein similar to ZP_00220026.1; hypothetical protein 27643..27852 Anaplasma marginale str. St. Maries 3171573 YP_153471.1 CDS thiG NC_004842.2 27915 28709 D functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 27915..28709 Anaplasma marginale str. St. Maries 3171499 YP_153472.1 CDS AM038 NC_004842.2 28807 29247 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(28807..29247) Anaplasma marginale str. St. Maries 3171078 YP_153473.1 CDS gltX NC_004842.2 29429 30754 D Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 29429..30754 Anaplasma marginale str. St. Maries 3171397 YP_153474.1 CDS AM041 NC_004842.2 31186 32391 D conserved hypothetical protein similar to ZP_00012590.1; hypothetical protein 31186..32391 Anaplasma marginale str. St. Maries 3171352 YP_153475.1 CDS AM042 NC_004842.2 32410 32967 D conserved family - methyltransferase; hypothetical protein 32410..32967 Anaplasma marginale str. St. Maries 3171732 YP_153476.1 CDS orfX NC_004842.2 33143 33541 R other copies include: AM030, AM065, AM077, AM082 AM210, AM717, AM723, AM989, AM1061, AM1149 and AM1253; member of msp2 superfamily; hypothetical protein complement(33143..33541) Anaplasma marginale str. St. Maries 3171052 YP_153477.1 CDS orfY NC_004842.2 33614 33847 R other copies include: AM032, AM063, AM721, AM990 AM1059 and AM1251; member of msp2 superfamily; hypothetical protein complement(33614..33847) Anaplasma marginale str. St. Maries 3171147 YP_153478.1 CDS rho NC_004842.2 36761 38125 R An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho complement(36761..38125) Anaplasma marginale str. St. Maries 3171526 YP_153479.1 CDS AM052 NC_004842.2 38234 38851 R conserved hypothetical protein similar to ZP_00211121.1; hypothetical protein complement(38234..38851) Anaplasma marginale str. St. Maries 3171838 YP_153480.1 CDS rpmI NC_004842.2 39269 39469 D COG0291 RpmI ribosomal protein L35; 50S ribosomal protein L35 39269..39469 Anaplasma marginale str. St. Maries 3171303 YP_153481.1 CDS rplT NC_004842.2 39496 39882 D binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 39496..39882 Anaplasma marginale str. St. Maries 3171707 YP_153482.1 CDS pheS NC_004842.2 39845 40900 D catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 39845..40900 Anaplasma marginale str. St. Maries 3171485 YP_153483.1 CDS AM056 NC_004842.2 40991 41749 D conserved family - dehydrogenase; hypothetical protein 40991..41749 Anaplasma marginale str. St. Maries 3170987 YP_153484.1 CDS glmU NC_004842.2 41930 43216 D COG1207 GlmU N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase); UDP-N-acetylglucosamine pyrophosphorylase 41930..43216 Anaplasma marginale str. St. Maries 3171039 YP_153485.1 CDS rpsP NC_004842.2 43369 43638 R binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 complement(43369..43638) Anaplasma marginale str. St. Maries 3171505 YP_153486.1 CDS proP1 NC_004842.2 43929 45215 D COG0477 ProP permeases of the major facilitator superfamily; similar to NP_359744.1; proline/betaine transport protein 43929..45215 Anaplasma marginale str. St. Maries 3171820 YP_153487.1 CDS orfY NC_004842.2 47834 48067 D other copies include: AM032, AM046, AM721, AM990 AM1059 and AM1251; member of msp2 superfamily; hypothetical protein 47834..48067 Anaplasma marginale str. St. Maries 3171639 YP_153488.1 CDS orfX NC_004842.2 48140 48535 D other copies include: AM030, AM044, AM077, AM082 AM210, AM717, AM723, AM989, AM1061, AM1149 and AM1253; member of msp2 superfamily; hypothetical protein 48140..48535 Anaplasma marginale str. St. Maries 3171398 YP_153489.1 CDS fpbA NC_004842.2 49429 50469 D iron binding protein FbpA precursor 49429..50469 Anaplasma marginale str. St. Maries 3171186 YP_153490.1 CDS AM070 NC_004842.2 50470 50649 D conserved hypothetical protein similar to ZP_00211126.1; hypothetical protein 50470..50649 Anaplasma marginale str. St. Maries 3171293 YP_153491.1 CDS AM071 NC_004842.2 50899 54888 R conserved hypothetical protein similar to NP_966764.1; hypothetical protein complement(50899..54888) Anaplasma marginale str. St. Maries 3171170 YP_153492.1 CDS AM072 NC_004842.2 55153 61272 D hypothetical protein identified by Glimmer 2; hypothetical protein 55153..61272 Anaplasma marginale str. St. Maries 3171650 YP_153493.1 CDS nrdR NC_004842.2 61443 61898 R conserved family - transcriptional regulator; NrdR family transcriptional regulator complement(61443..61898) Anaplasma marginale str. St. Maries 3171580 YP_153494.1 CDS AM074 NC_004842.2 62431 62886 D conserved family - ABC transporter; hypothetical protein 62431..62886 Anaplasma marginale str. St. Maries 3171641 YP_153495.1 CDS omp14 NC_004842.2 63055 64269 D member of msp2 superfamily; outer membrane protein 14 63055..64269 Anaplasma marginale str. St. Maries 3171517 YP_153496.1 CDS orfX NC_004842.2 64841 65242 R other copies include: AM030, AM044, AM065, AM082 AM210, AM717, AM723, AM989, AM1061, AM1149 and AM1253; member of msp2 superfamily; hypothetical protein complement(64841..65242) Anaplasma marginale str. St. Maries 3171233 YP_153497.1 CDS orfX NC_004842.2 67571 67978 D other copies include: AM030, AM044, AM065, AM077 AM210, AM717, AM723, AM989, AM1061, AM1149 and AM1253; member of msp2 superfamily; hypothetical protein 67571..67978 Anaplasma marginale str. St. Maries 3171162 YP_153498.1 CDS recA NC_004842.2 68810 69889 D catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 68810..69889 Anaplasma marginale str. St. Maries 3171549 YP_153499.1 CDS pyrE NC_004842.2 69984 70586 D involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 69984..70586 Anaplasma marginale str. St. Maries 3171737 YP_153500.1 CDS thiF NC_004842.2 70620 71426 D COG0476 ThiF dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family; thiamine biosynthesis protein 70620..71426 Anaplasma marginale str. St. Maries 3171205 YP_153501.1 CDS msp4 NC_004842.2 71782 72630 R similar to AAG34715.1; member of msp2 superfamily; major surface protein 4 complement(71782..72630) Anaplasma marginale str. St. Maries 3171420 YP_153502.1 CDS AM092 NC_004842.2 75388 76326 R conserved hypothetical protein similar to NP_220824.1; hypothetical protein complement(75388..76326) Anaplasma marginale str. St. Maries 3171198 YP_153503.1 CDS AM093 NC_004842.2 76411 76731 R conserved family - oxidoreductase; hypothetical protein complement(76411..76731) Anaplasma marginale str. St. Maries 3171014 YP_153504.1 CDS AM094 NC_004842.2 76781 76984 D hypothetical protein identified by Glimmer 2; hypothetical protein 76781..76984 Anaplasma marginale str. St. Maries 3171848 YP_153505.1 CDS trxA NC_004842.2 77419 77766 R COG0526 TrxA thiol-disulfide isomerase and thioredoxins; thioredoxin complement(77419..77766) Anaplasma marginale str. St. Maries 3171112 YP_153506.1 CDS trbG NC_004842.2 77775 78587 R conjugal transfer protein trbG precursor complement(77775..78587) Anaplasma marginale str. St. Maries 3171574 YP_153507.1 CDS pdhA NC_004842.2 78838 79956 R pyruvate dehydrogenase E1 component, subunit alpha precursor complement(78838..79956) Anaplasma marginale str. St. Maries 3171308 YP_153508.1 CDS rrf NC_004842.2 79928 80869 R conserved family - hydrolase; hypothetical protein complement(79928..80869) Anaplasma marginale str. St. Maries 3171142 YP_153509.1 CDS guaB NC_004842.2 84517 85998 R COG0516 GuaB IMP dehydrogenase/GMP reductase; inosine monophosphate dehydrogenase complement(84517..85998) Anaplasma marginale str. St. Maries 3171492 YP_153510.1 CDS ppnK NC_004842.2 86056 86820 R catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase complement(86056..86820) Anaplasma marginale str. St. Maries 3171001 YP_153511.2 CDS rpmE NC_004842.2 86873 87094 R RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 complement(86873..87094) Anaplasma marginale str. St. Maries 3171141 YP_153512.1 CDS fabD NC_004842.2 87396 88415 D COG0331 FabD (ACP S-malonyltransferase); similar to NP_221088.1; malonyl CoA-ACP transacylase 87396..88415 Anaplasma marginale str. St. Maries 3171092 YP_153513.1 CDS tmk NC_004842.2 88417 89052 D catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 88417..89052 Anaplasma marginale str. St. Maries 3171433 YP_153514.1 CDS AM112 NC_004842.2 89107 90375 D conserved family - permease; hypothetical protein 89107..90375 Anaplasma marginale str. St. Maries 3170952 YP_153515.1 CDS AM113 NC_004842.2 90533 91186 R conserved hypothetical protein similar to ZP_00211094.1; hypothetical protein complement(90533..91186) Anaplasma marginale str. St. Maries 3171779 YP_153516.1 CDS secB NC_004842.2 91268 91795 D molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 91268..91795 Anaplasma marginale str. St. Maries 3171229 YP_153517.1 CDS AM116 NC_004842.2 91749 92567 D conserved hypothetical protein similar to NP_966778.1; hypothetical protein 91749..92567 Anaplasma marginale str. St. Maries 3171240 YP_153518.1 CDS mpp NC_004842.2 92821 94131 R COG0612 PqqL predicted Zn-dependent peptidases; similar to NP_220605.1; mitochondrial processing protease complement(92821..94131) Anaplasma marginale str. St. Maries 3171938 YP_153519.1 CDS AM118 NC_004842.2 94178 95500 D conserved family - M23/M37 peptidase domain protein; hypothetical protein 94178..95500 Anaplasma marginale str. St. Maries 3171115 YP_153520.1 CDS AM119 NC_004842.2 95806 97209 D conserved family - dioxygenase; hypothetical protein 95806..97209 Anaplasma marginale str. St. Maries 3171577 YP_153521.1 CDS ribA NC_004842.2 97306 97923 R catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha complement(97306..97923) Anaplasma marginale str. St. Maries 3171621 YP_153522.1 CDS AM122 NC_004842.2 97418 98149 D hypothetical protein identified by Glimmer 2; hypothetical protein 97418..98149 Anaplasma marginale str. St. Maries 3171586 YP_153523.1 CDS msp1B-2 NC_004842.2 98205 100475 R member of msp1b gene family, full length gene 2 other copy is AM180; member of msp1 superfamily; major surface protein 1B-2 complement(98205..100475) Anaplasma marginale str. St. Maries 3171775 YP_153524.1 CDS msp1bpg2 NC_004842.2 100706 101902 R member of msp1b gene family, partial gene 2; member of msp1 superfamily; major surface protein 1B complement(100706..101902) Anaplasma marginale str. St. Maries 3171612 YP_153525.1 CDS mfd NC_004842.2 101880 105338 R COG1197 Mfd transcription-repair coupling factor - superfamily II helicase; transcription repair coupling factor complement(101880..105338) Anaplasma marginale str. St. Maries 3171275 YP_153526.1 CDS rnhA NC_004842.2 105394 105909 D COG0328 RnhA ribonuclease HI; similar to NP_767956.1; ribonuclease H 105394..105909 Anaplasma marginale str. St. Maries 3171655 YP_153527.1 CDS AM127 NC_004842.2 105919 108918 D conserved hypothetical protein similar to ZP_00211075.1; hypothetical protein 105919..108918 Anaplasma marginale str. St. Maries 3171296 YP_153528.1 CDS pyrH NC_004842.2 109082 109843 D Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 109082..109843 Anaplasma marginale str. St. Maries 3171801 YP_153529.1 CDS frr NC_004842.2 109852 110403 D Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 109852..110403 Anaplasma marginale str. St. Maries 3171583 YP_153530.1 CDS uppS NC_004842.2 110416 111114 D COG0020 UppS undecaprenyl pyrophosphate synthase; undecaprenyl diphosphate synthase 110416..111114 Anaplasma marginale str. St. Maries 3171217 YP_153531.1 CDS cdsA NC_004842.2 111068 111952 D COG0575 CdsA CDP-diglyceride synthetase; phosphatidate cytidylyltransferase 111068..111952 Anaplasma marginale str. St. Maries 3171095 YP_153532.1 CDS msp1Bpg3 NC_004842.2 112247 114160 R member of msp1b gene family, partial gene 3; member of msp1 superfamily; major surface protein 1B complement(112247..114160) Anaplasma marginale str. St. Maries 3170980 YP_153533.1 CDS AM136 NC_004842.2 114304 117225 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(114304..117225) Anaplasma marginale str. St. Maries 3171478 YP_153534.1 CDS purC NC_004842.2 117369 118097 R COG0152 PurC phosphoribosylaminoimidazole-succinocarboxamide (SAICAR); phosphoribosylaminoimidazole-succinocarboxamide synthase complement(117369..118097) Anaplasma marginale str. St. Maries 3170977 YP_153535.1 CDS hisS NC_004842.2 118215 119507 D catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 118215..119507 Anaplasma marginale str. St. Maries 3171099 YP_153536.1 CDS AM139 NC_004842.2 119517 120272 R conserved family - disulfide oxidoreductase; hypothetical protein complement(119517..120272) Anaplasma marginale str. St. Maries 3171585 YP_153537.1 CDS coxW NC_004842.2 120631 121656 D COG3175 COX11 cytochrome oxidase assembly factor; cytochrome C oxidase assembly protein 120631..121656 Anaplasma marginale str. St. Maries 3170971 YP_153538.1 CDS panB NC_004842.2 121691 122524 D catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 121691..122524 Anaplasma marginale str. St. Maries 3171037 YP_153539.1 CDS ccmA NC_004842.2 122666 123292 R ATP-binding protein; required for proper cytochrome C maturation; cytochrome C biogenesis protein CcmA complement(122666..123292) Anaplasma marginale str. St. Maries 3171443 YP_153540.1 CDS murA NC_004842.2 123325 124611 R adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase complement(123325..124611) Anaplasma marginale str. St. Maries 3171180 YP_153541.1 CDS dcd NC_004842.2 124613 125170 R Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase complement(124613..125170) Anaplasma marginale str. St. Maries 3171480 YP_153542.1 CDS AM148 NC_004842.2 125269 126114 R conserved hypothetical protein similar to NP_966731.1; hypothetical protein complement(125269..126114) Anaplasma marginale str. St. Maries 3171007 YP_153543.1 CDS cspA NC_004842.2 126498 126776 D COG1278 CspC cold shock proteins; cold shock protein 126498..126776 Anaplasma marginale str. St. Maries 3171825 YP_153544.1 CDS ntrY NC_004842.2 126818 128905 D COG0347 GlnK nitrogen regulatory protein PII; similar to NP_420550.1; nitrogen regulation protein 126818..128905 Anaplasma marginale str. St. Maries 3171243 YP_153545.1 CDS rnd NC_004842.2 128874 130079 D COG0349 Rnd ribonuclease D; similar to NP_531848.1; other copies include: AM1015; ribonuclease D 128874..130079 Anaplasma marginale str. St. Maries 3171717 YP_153546.1 CDS ligA NC_004842.2 130162 132183 R COG0272 Lig NAD-dependent DNA ligase; DNA ligase complement(130162..132183) Anaplasma marginale str. St. Maries 3171105 YP_153547.1 CDS grxC2 NC_004842.2 132192 132524 R similar to NP_772351.1; glutaredoxin-like protein GRLA complement(132192..132524) Anaplasma marginale str. St. Maries 3171450 YP_153548.1 CDS AM154 NC_004842.2 132514 132750 R conserved hypothetical protein similar to NP_966273.1; hypothetical protein complement(132514..132750) Anaplasma marginale str. St. Maries 3171729 YP_153549.1 CDS AM156 NC_004842.2 132894 133445 R conserved family - thioredoxin; hypothetical protein complement(132894..133445) Anaplasma marginale str. St. Maries 3171607 YP_153550.1 CDS radA NC_004842.2 133393 134763 R Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA complement(133393..134763) Anaplasma marginale str. St. Maries 3171497 YP_153551.1 CDS AM159 NC_004842.2 135010 137652 D conserved family - TRAP-type uncharacterized transport system, fused permease; hypothetical protein 135010..137652 Anaplasma marginale str. St. Maries 3171431 YP_153552.1 CDS AM160 NC_004842.2 137659 138246 D conserved family - uncharacterized membrane protein, required for colicin V production; hypothetical protein 137659..138246 Anaplasma marginale str. St. Maries 3171236 YP_153553.1 CDS rpsF NC_004842.2 138257 138640 D binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 138257..138640 Anaplasma marginale str. St. Maries 3171189 YP_153554.1 CDS rpsR NC_004842.2 138716 138943 D binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 138716..138943 Anaplasma marginale str. St. Maries 3171184 YP_153555.1 CDS rplI NC_004842.2 138963 139625 D in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 138963..139625 Anaplasma marginale str. St. Maries 3171524 YP_153556.1 CDS glyA NC_004842.2 139651 140943 D catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 139651..140943 Anaplasma marginale str. St. Maries 3171408 YP_153557.1 CDS AM166 NC_004842.2 141074 141415 D conserved family - CyaY protein; hypothetical protein 141074..141415 Anaplasma marginale str. St. Maries 3171892 YP_153558.1 CDS msbA2 NC_004842.2 141396 143144 D COG1132 MdlB ABC-type multidrug/protein/lipid transport system, ATPase component; ABC transporter 141396..143144 Anaplasma marginale str. St. Maries 3171700 YP_153559.1 CDS sdhA NC_004842.2 143415 145214 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 143415..145214 Anaplasma marginale str. St. Maries 3171669 YP_153560.1 CDS sdhB NC_004842.2 145239 146027 D part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 145239..146027 Anaplasma marginale str. St. Maries 3171556 YP_153561.1 CDS thyX NC_004842.2 146028 146903 D flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase 146028..146903 Anaplasma marginale str. St. Maries 3171755 YP_153562.1 CDS bcr2 NC_004842.2 147040 148221 D bicyclomycin resistance protein; similar to NP_416687.1; bicyclomycin resistance protein 147040..148221 Anaplasma marginale str. St. Maries 3171101 YP_153563.1 CDS ruvB NC_004842.2 148363 149358 R promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB complement(148363..149358) Anaplasma marginale str. St. Maries 3171768 YP_153564.1 CDS ruvA NC_004842.2 149355 149927 R plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA complement(149355..149927) Anaplasma marginale str. St. Maries 3171168 YP_153565.1 CDS ccmc NC_004842.2 149924 150676 R COG0755 CcmC ABC-type transport system involved in cytochrome C biogenesis, permease component; heme exporter protein C complement(149924..150676) Anaplasma marginale str. St. Maries 3171705 YP_153566.1 CDS gmk NC_004842.2 150861 151595 D COG0194 Gmk guanylate kinase; guanylate kinase 150861..151595 Anaplasma marginale str. St. Maries 3171656 YP_153567.1 CDS AM178 NC_004842.2 151721 152833 D conserved hypothetical protein similar to NP_630160.1; hypothetical protein 151721..152833 Anaplasma marginale str. St. Maries 3171210 YP_153568.1 CDS folD NC_004842.2 152987 153886 D COG0190 FolD 5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase; methylenetetrahydrofolate dehydrogenase 152987..153886 Anaplasma marginale str. St. Maries 3171662 YP_153569.1 CDS msp1B-1 NC_004842.2 154357 156576 D member of msp1b gene family, full length gene 1 other copy is AM123; member of msp1 superfamily; major surface protein 1B-1 154357..156576 Anaplasma marginale str. St. Maries 3171380 YP_153570.1 CDS AM185 NC_004842.2 157060 159456 D hypothetical protein identified by Glimmer 2; hypothetical protein 157060..159456 Anaplasma marginale str. St. Maries 3171918 YP_153571.1 CDS msp1Bpg1 NC_004842.2 159495 159944 R member of msp1b gene family, partial gene 1; member of msp1 superfamily; similar to AAD20331.1; major surface protein 1B complement(159495..159944) Anaplasma marginale str. St. Maries 3171928 YP_153572.1 CDS AM189 NC_004842.2 160185 160817 R conserved family - hydrolase or acyltransferase; hypothetical protein complement(160185..160817) Anaplasma marginale str. St. Maries 3171195 YP_153573.1 CDS cycM NC_004842.2 161059 161598 R COG3303 NrfA formate-dependent nitrite reductase, periplasmic cytochrome C552 subunit; cytochrome C complement(161059..161598) Anaplasma marginale str. St. Maries 3171724 YP_153574.1 CDS nuoL2 NC_004842.2 161998 163518 R COG1009 NuoL NADH:ubiquinone oxidoreductase subunit 5 (chain L)/multisubunit Na+/H+ antiporter, MnhA; similar to NP_220667.1; NADH dehydrogenase I subunit L complement(161998..163518) Anaplasma marginale str. St. Maries 3171318 YP_153575.1 CDS ppdK NC_004842.2 163888 166542 R catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase complement(163888..166542) Anaplasma marginale str. St. Maries 3171387 YP_153576.1 CDS AM197 NC_004842.2 166838 167347 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(166838..167347) Anaplasma marginale str. St. Maries 3171508 YP_153577.1 CDS AM198 NC_004842.2 167350 167973 R conserved family - phosphatase; hypothetical protein complement(167350..167973) Anaplasma marginale str. St. Maries 3171744 YP_153578.1 CDS aspS NC_004842.2 168165 169142 R COG0173 AspS aspartyl-tRNA synthetase; open reading frame split domain with AM200; asparaginyl-tRNA synthetase complement(168165..169142) Anaplasma marginale str. St. Maries 3171337 YP_153579.1 CDS aspS NC_004842.2 169054 169944 R COG0173 AspS aspartyl-tRNA synthetase; open reading frame split domain with AM199; asparaginyl-tRNA synthetase complement(169054..169944) Anaplasma marginale str. St. Maries 3171557 YP_153580.1 CDS AM202 NC_004842.2 170363 170950 D conserved hypothetical protein similar to NP_360175.1; hypothetical protein 170363..170950 Anaplasma marginale str. St. Maries 3171626 YP_153581.1 CDS gshB NC_004842.2 170965 171891 D catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 170965..171891 Anaplasma marginale str. St. Maries 3171246 YP_153582.1 CDS ddl NC_004842.2 172027 173031 D D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 172027..173031 Anaplasma marginale str. St. Maries 3171882 YP_153583.1 CDS ftsQ NC_004842.2 173024 173797 D COG1589 FtsQ cell division septal protein; cell division protein 173024..173797 Anaplasma marginale str. St. Maries 3170970 YP_153584.1 CDS ntrX NC_004842.2 174038 175438 D COG3852 NtrB signal transduction histidine kinase, nitrogen specific; similar to AAL08835.1; nitrogen assimilation regulatory protein 174038..175438 Anaplasma marginale str. St. Maries 3171290 YP_153585.1 CDS orfX NC_004842.2 175825 176214 D other copies include: AM030, AM044, AM065, AM077 AM082, AM717, AM723, AM989, AM1061, AM1149 and AM1253; member of msp2 superfamily; hypothetical protein 175825..176214 Anaplasma marginale str. St. Maries 3171183 YP_153586.1 CDS gor NC_004842.2 177599 179011 R COG1249 Lpd dihydrolipoamide dehydrogenase/glutathione oxidoreductase; similar to EAA26057.1; glutathione reductase complement(177599..179011) Anaplasma marginale str. St. Maries 3171874 YP_153587.1 CDS AM216 NC_004842.2 179210 181738 D hypothetical protein identified by Glimmer 2; hypothetical protein 179210..181738 Anaplasma marginale str. St. Maries 3171542 YP_153588.1 CDS AM217 NC_004842.2 181807 183273 D conserved hypothetical protein similar to NP_966526.1; hypothetical protein 181807..183273 Anaplasma marginale str. St. Maries 3171334 YP_153589.1 CDS AM218 NC_004842.2 183273 183896 D conserved hypothetical protein similar to ZP_00210423.1; hypothetical protein 183273..183896 Anaplasma marginale str. St. Maries 3171169 YP_153590.1 CDS AM219 NC_004842.2 183893 184429 D conserved hypothetical protein similar to ZP_00210422.1; hypothetical protein 183893..184429 Anaplasma marginale str. St. Maries 3171783 YP_153591.1 CDS AM220 NC_004842.2 184598 185461 D conserved family - metal-dependent hydrolase; hypothetical protein 184598..185461 Anaplasma marginale str. St. Maries 3171509 YP_153592.1 CDS glnA NC_004842.2 185456 186283 R COG0174 GlnA glutamine synthase; other copies include: AM1206; glutamine synthetase complement(185456..186283) Anaplasma marginale str. St. Maries 3171110 YP_153593.1 CDS pstC NC_004842.2 186261 187388 R COG0573 PstC ABC-type phosphate transport system, permease component; similar to NP_531125.1; phosphate ABC transporter permease complement(186261..187388) Anaplasma marginale str. St. Maries 3170945 YP_153594.1 CDS alaS NC_004842.2 187473 190121 D Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 187473..190121 Anaplasma marginale str. St. Maries 3171157 YP_153595.1 CDS sucD NC_004842.2 190828 191712 R COG0074 SucD succinyl-CoA synthetase subunit alpha; similar to EAA25376.1; succinyl-CoA ligase subunit alpha complement(190828..191712) Anaplasma marginale str. St. Maries 3171312 YP_153596.1 CDS sucC NC_004842.2 191721 192887 R catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta complement(191721..192887) Anaplasma marginale str. St. Maries 3171455 YP_153597.2 CDS rpsU NC_004842.2 192990 193253 R a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 complement(192990..193253) Anaplasma marginale str. St. Maries 3171375 YP_153598.1 CDS pstS NC_004842.2 193361 194377 R COG0226 ABC-type phosphate transport system periplasmic component; phosphate ABC transporter substrate-binding protein complement(193361..194377) Anaplasma marginale str. St. Maries 3171087 YP_153599.1 CDS msp5 NC_004842.2 194437 195069 R similar to AAB02878.1; major surface protein 5 complement(194437..195069) Anaplasma marginale str. St. Maries 3171292 YP_153600.1 CDS AM237 NC_004842.2 195252 196268 R conserved family - 2-nitropropane dioxygenase; hypothetical protein complement(195252..196268) Anaplasma marginale str. St. Maries 3171868 YP_153601.1 CDS cybB NC_004842.2 196271 196813 R COG3038 CybB cytochrome B561; similar to ZP_00011855.1; cytochrome b561 complement(196271..196813) Anaplasma marginale str. St. Maries 3171464 YP_153602.1 CDS AM240 NC_004842.2 197126 198754 D conserved family - ABC transporter permease protein; hypothetical protein 197126..198754 Anaplasma marginale str. St. Maries 3171547 YP_153603.1 CDS aprE NC_004842.2 198949 200487 R COG1404 aprE subtilisin-like serine proteases; similar to EAA25533.1; alkaline protease secretion protein complement(198949..200487) Anaplasma marginale str. St. Maries 3171917 YP_153604.1 CDS AM242 NC_004842.2 200575 201231 R conserved hypothetical protein similar to NP_966600.1; hypothetical protein complement(200575..201231) Anaplasma marginale str. St. Maries 3171145 YP_153605.1 CDS murD NC_004842.2 201697 203013 D COG0771 MurD UDP-N-acetylmuramoylalanine-D-glutamate ligase; UDP-N-acetylmuramoylalanine--D-glutamate ligase 201697..203013 Anaplasma marginale str. St. Maries 3171617 YP_153606.1 CDS tolB NC_004842.2 203038 204363 R forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB complement(203038..204363) Anaplasma marginale str. St. Maries 3171160 YP_153607.1 CDS AM245 NC_004842.2 204370 205998 R conserved family - metallo-beta-lactamase; hypothetical protein complement(204370..205998) Anaplasma marginale str. St. Maries 3171510 YP_153608.1 CDS AM247 NC_004842.2 206240 206812 D hypothetical protein identified by Glimmer 2; hypothetical protein 206240..206812 Anaplasma marginale str. St. Maries 3171390 YP_153609.1 CDS AM248 NC_004842.2 206845 208338 D conserved hypothetical protein similar to ZP_00210406.1; hypothetical protein 206845..208338 Anaplasma marginale str. St. Maries 3171504 YP_153610.1 CDS rpsL NC_004842.2 208523 208897 D interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 208523..208897 Anaplasma marginale str. St. Maries 3171629 YP_153611.1 CDS rpsG NC_004842.2 208915 209397 D binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 208915..209397 Anaplasma marginale str. St. Maries 3171302 YP_153612.1 CDS fusA NC_004842.2 209431 211503 D EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 209431..211503 Anaplasma marginale str. St. Maries 3171791 YP_153613.1 CDS tuf NC_004842.2 211515 212696 D EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 211515..212696 Anaplasma marginale str. St. Maries 3170990 YP_153614.1 CDS secE NC_004842.2 212796 213008 D forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 212796..213008 Anaplasma marginale str. St. Maries 3171545 YP_153615.1 CDS nusG NC_004842.2 212992 213558 D COG0250 NusG transcription antiterminator; transcription antitermination protein 212992..213558 Anaplasma marginale str. St. Maries 3171068 YP_153616.1 CDS rplK NC_004842.2 213562 214005 D binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 213562..214005 Anaplasma marginale str. St. Maries 3171370 YP_153617.2 CDS rplA NC_004842.2 214002 214676 D in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 214002..214676 Anaplasma marginale str. St. Maries 3171013 YP_153618.1 CDS rplJ NC_004842.2 214712 215203 D binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 214712..215203 Anaplasma marginale str. St. Maries 3171560 YP_153619.1 CDS rplL NC_004842.2 215328 215732 D present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 215328..215732 Anaplasma marginale str. St. Maries 3171055 YP_153620.1 CDS rpoB NC_004842.2 215769 219917 D DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 215769..219917 Anaplasma marginale str. St. Maries 3171249 YP_153621.1 CDS rpoC NC_004842.2 219929 224176 D COG0086 RpoC DNA-directed RNA polymerase beta subunit/160 kD subunit; DNA-directed RNA polymerase subunit beta' 219929..224176 Anaplasma marginale str. St. Maries 3171291 YP_153622.1 CDS rnhB NC_004842.2 224173 225192 R COG0164 RnhB ribonuclease HII; ribonuclease HII complement(224173..225192) Anaplasma marginale str. St. Maries 3171377 YP_153623.1 CDS AM265 NC_004842.2 225409 228828 D hypothetical protein identified by Glimmer 2; hypothetical protein 225409..228828 Anaplasma marginale str. St. Maries 3171618 YP_153624.1 CDS AM266 NC_004842.2 229023 229526 R conserved hypothetical protein similar to NP_965966.1; hypothetical protein complement(229023..229526) Anaplasma marginale str. St. Maries 3171447 YP_153625.1 CDS AM268 NC_004842.2 229773 230915 R conserved family - 7-keto-8-aminopelargonate synthetase; hypothetical protein complement(229773..230915) Anaplasma marginale str. St. Maries 3171093 YP_153626.1 CDS AM270 NC_004842.2 231322 231849 D conserved family - Na+/H+ antiporter; hypothetical protein 231322..231849 Anaplasma marginale str. St. Maries 3171097 YP_153627.1 CDS AM271 NC_004842.2 231937 232710 R type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase complement(231937..232710) Anaplasma marginale str. St. Maries 3171774 YP_153628.1 CDS pyrD NC_004842.2 232717 233886 R catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 complement(232717..233886) Anaplasma marginale str. St. Maries 3171809 YP_153629.1 CDS AM275 NC_004842.2 234047 234637 D conserved family - N-formylmethionyl-tRNA deformylase; hypothetical protein 234047..234637 Anaplasma marginale str. St. Maries 3171511 YP_153630.1 CDS AM276 NC_004842.2 234769 235521 D conserved family -; hypothetical protein 234769..235521 Anaplasma marginale str. St. Maries 3171231 YP_153631.1 CDS AM279 NC_004842.2 235885 236751 D conserved hypothetical protein similar to ZP_00073278.1; hypothetical protein 235885..236751 Anaplasma marginale str. St. Maries 3171552 YP_153632.1 CDS pdxH NC_004842.2 236889 237488 D COG0259 PdxH pyridoxamine phosphate oxidase; pyridoxamine 5-phosphate oxidase 236889..237488 Anaplasma marginale str. St. Maries 3171784 YP_153633.1 CDS murE NC_004842.2 237493 238911 R COG0769 MurE UDP-N-acetylmuramyl tripeptide synthase; UDP-N-acetylmuramoylalanyl-D-glutamate 2,6-diaminopimelate ligase complement(237493..238911) Anaplasma marginale str. St. Maries 3171129 YP_153634.1 CDS AM283 NC_004842.2 238895 239110 D hypothetical protein identified by Glimmer 2; hypothetical protein 238895..239110 Anaplasma marginale str. St. Maries 3171146 YP_153635.1 CDS metC NC_004842.2 239132 240358 R COG0626 cystathionine beta-lyases/cystathionine gamma-synthases; cystathionine beta-lyase complement(239132..240358) Anaplasma marginale str. St. Maries 3171537 YP_153636.1 CDS bolA NC_004842.2 240312 240785 R COG0271 BolA stress-induced morphogen (activity unknown); bolA like protein complement(240312..240785) Anaplasma marginale str. St. Maries 3171919 YP_153637.1 CDS AM286 NC_004842.2 240922 241857 D conserved hypothetical protein similar to ZP_00210378.1; hypothetical protein 240922..241857 Anaplasma marginale str. St. Maries 3171484 YP_153638.1 CDS dnaE NC_004842.2 242268 245651 D COG0587 DnaE DNA polymerase III subunit alpha; DNA polymerase III subunit alpha 242268..245651 Anaplasma marginale str. St. Maries 3171610 YP_153639.1 CDS rrs NC_004842.2 245891 247279 D COG0128 AroA 5-enolpyruvylshikimate-3-phosphate synthase; 3-phosphoshikimate 1-carboxyvinyltransferase 245891..247279 Anaplasma marginale str. St. Maries 3171878 YP_153640.1 CDS sdhC NC_004842.2 249067 249450 D COG2009 SdhC succinate dehydrogenase/fumarate reductase cytochrome b subunit; similar to AAL60178.1; succinate dehydrogenase cytochrome b556 subunit 249067..249450 Anaplasma marginale str. St. Maries 3171064 YP_153641.1 CDS AM291 NC_004842.2 249312 249686 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(249312..249686) Anaplasma marginale str. St. Maries 3171608 YP_153642.1 CDS sdhD NC_004842.2 249441 249791 D COG2142 SdhD succinate dehydrogenase hydrophobic anchor subunit; succinate dehyrdrogenase subunit D 249441..249791 Anaplasma marginale str. St. Maries 3171003 YP_153643.1 CDS pep1 NC_004842.2 249942 251312 D similar to AAS89251.2; hypothetical protein 249942..251312 Anaplasma marginale str. St. Maries 3171714 YP_153644.1 CDS thiD NC_004842.2 251856 252638 R COG0351 ThiD hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; similar to NP_422017.1; phosphomethylpyrimidine kinase complement(251856..252638) Anaplasma marginale str. St. Maries 3171252 YP_153645.1 CDS AM296 NC_004842.2 252646 253311 R conserved family - ATPase involved in DNA replication; hypothetical protein complement(252646..253311) Anaplasma marginale str. St. Maries 3171288 YP_153646.1 CDS perM NC_004842.2 253312 254664 R COG0628 PerM predicted permease; similar to NP_385291.1; permease perM-like complement(253312..254664) Anaplasma marginale str. St. Maries 3171702 YP_153647.1 CDS AM299 NC_004842.2 254937 255290 R conserved hypothetical protein similar to NP_966181.1; hypothetical protein complement(254937..255290) Anaplasma marginale str. St. Maries 3171914 YP_153648.1 CDS rpsD NC_004842.2 255537 256073 D Binds directly to 16S rRNA where it nucleates assembly of the 30S subunit; 30S ribosomal protein S4 255537..256073 Anaplasma marginale str. St. Maries 3171128 YP_153649.1 CDS AM302 NC_004842.2 256490 257638 R conserved hypothetical protein similar to ZP_00210366.1; hypothetical protein complement(256490..257638) Anaplasma marginale str. St. Maries 3171176 YP_153650.1 CDS AM303 NC_004842.2 257698 258471 R conserved family - acetyltransferase; hypothetical protein complement(257698..258471) Anaplasma marginale str. St. Maries 3171392 YP_153651.1 CDS pgpA NC_004842.2 258486 259010 R COG1267 PgpA phosphatidlglycerophosphatase A; phosphatidylglycerophosphatase A complement(258486..259010) Anaplasma marginale str. St. Maries 3171601 YP_153652.1 CDS AM306 NC_004842.2 259077 259331 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(259077..259331) Anaplasma marginale str. St. Maries 3170975 YP_153653.1 CDS tig NC_004842.2 259718 261118 D COG0544 Tig FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor); similar to NP_420771.1; trigger factor 259718..261118 Anaplasma marginale str. St. Maries 3171486 YP_153654.1 CDS clpP NC_004842.2 261123 261770 D hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 261123..261770 Anaplasma marginale str. St. Maries 3171752 YP_153655.1 CDS clpX NC_004842.2 261780 262997 D binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 261780..262997 Anaplasma marginale str. St. Maries 3171228 YP_153656.1 CDS lon NC_004842.2 263016 265442 D COG0466 Lon ATP-dependent Lon protease bacterial type; ATP-dependent protease LA 263016..265442 Anaplasma marginale str. St. Maries 3171410 YP_153657.1 CDS fmt NC_004842.2 265965 266870 D COG0223 Fmt methionyl-tRNA formyltransferase; methionyl-tRNA formyltransferase 265965..266870 Anaplasma marginale str. St. Maries 3171728 YP_153658.1 CDS AM315 NC_004842.2 267028 267861 D conserved hypothetical protein similar to ZP_00210358.1; hypothetical protein 267028..267861 Anaplasma marginale str. St. Maries 3171471 YP_153659.1 CDS AM316 NC_004842.2 268029 268904 D conserved hypothetical protein similar to NP_966137.1; hypothetical protein 268029..268904 Anaplasma marginale str. St. Maries 3171841 YP_153660.1 CDS thiE NC_004842.2 269317 270339 D COG0352 ThiE thiamine monophosphate synthase; similar to NP_229721.1; thiamin monophosphate synthase 269317..270339 Anaplasma marginale str. St. Maries 3171800 YP_153661.1 CDS AM320 NC_004842.2 270586 271899 R conserved hypothetical protein similar to ZP_00210354.1; hypothetical protein complement(270586..271899) Anaplasma marginale str. St. Maries 3171319 YP_153662.1 CDS AM321 NC_004842.2 272040 272318 D conserved hypothetical protein similar to NP_965941.1; hypothetical protein 272040..272318 Anaplasma marginale str. St. Maries 3171833 YP_153663.1 CDS ftsK NC_004842.2 272293 274566 D COG1674 FtsK DNA segregation ATPase FtsK/SpoIIIE and related proteins; similar to NP_533424.1; cell division protein 272293..274566 Anaplasma marginale str. St. Maries 3171534 YP_153664.1 CDS AM324 NC_004842.2 274841 275893 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(274841..275893) Anaplasma marginale str. St. Maries 3171458 YP_153665.1 CDS argD NC_004842.2 276120 277298 R DapATase; functions in arginine biosynthetic pathway; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine transaminase complement(276120..277298) Anaplasma marginale str. St. Maries 3171923 YP_153666.1 CDS barA NC_004842.2 277480 278886 D COG0642 BaeS signal transduction histidine kinase; similar to NP_220615.1; histidine kinase sensor protein 277480..278886 Anaplasma marginale str. St. Maries 3171767 YP_153667.1 CDS AM328 NC_004842.2 278900 279751 R conserved hypothetical protein similar to NP_966025.1; hypothetical protein complement(278900..279751) Anaplasma marginale str. St. Maries 3171772 YP_153668.1 CDS tolR NC_004842.2 279717 280193 R N: COG0848 ExbD biopolymer transport protein; TolR protein complement(279717..280193) Anaplasma marginale str. St. Maries 3171116 YP_153669.1 CDS tolQ NC_004842.2 280174 280866 R COG0811 TolQ biopolymer transport protein; TolQ protein complement(280174..280866) Anaplasma marginale str. St. Maries 3171323 YP_153670.1 CDS mutL NC_004842.2 281043 282227 D COG0323 MutL DNA mismatch repair enzyme (predicted ATPase); open reading frame split domain with AM333; DNA mismatch repair protein 281043..282227 Anaplasma marginale str. St. Maries 3171130 YP_153671.1 CDS mutL NC_004842.2 282274 282939 D COG0323 MutL DNA mismatch repair enzyme (predicted ATPase); open reading frame split domain with AM332; DNA mismatch repair protein 282274..282939 Anaplasma marginale str. St. Maries 3171120 YP_153672.1 CDS smf NC_004842.2 282953 284086 R COG0758 Smf predicted Rossmann fold nucleotide-binding protein involved in DNA uptake; DNA processing protein subunit A complement(282953..284086) Anaplasma marginale str. St. Maries 3171256 YP_153673.1 CDS mnmA NC_004842.2 284565 285728 R catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA complement(284565..285728) Anaplasma marginale str. St. Maries 3170961 YP_153674.1 CDS AM336 NC_004842.2 285916 286938 R conserved family - twitching mobility protein; hypothetical protein complement(285916..286938) Anaplasma marginale str. St. Maries 3171663 YP_153675.1 CDS fabB NC_004842.2 287239 288522 R COG0304 FabB 3-oxoacyl-(ACP synthase); 3-oxoacyl-ACP synthase complement(287239..288522) Anaplasma marginale str. St. Maries 3171750 YP_153676.1 CDS acpP NC_004842.2 288627 288974 R COG0236 AcpP ACP; similar to NP_221115.1; acyl-carrier protein complement(288627..288974) Anaplasma marginale str. St. Maries 3171665 YP_153677.1 CDS rpmG NC_004842.2 289573 289743 R in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 complement(289573..289743) Anaplasma marginale str. St. Maries 3171079 YP_153678.1 CDS AM342 NC_004842.2 289888 290631 D conserved hypothetical protein similar to NP_965975.1; hypothetical protein 289888..290631 Anaplasma marginale str. St. Maries 3171539 YP_153679.1 CDS AM343 NC_004842.2 290619 291137 D conserved family - disulfide bond formation protein; hypothetical protein 290619..291137 Anaplasma marginale str. St. Maries 3171354 YP_153680.1 CDS AM345 NC_004842.2 291311 291622 D hypothetical protein identified by Glimmer 2; hypothetical protein 291311..291622 Anaplasma marginale str. St. Maries 3171907 YP_153681.1 CDS AM346 NC_004842.2 292131 292970 D hypothetical protein identified by Glimmer 2; hypothetical protein 292131..292970 Anaplasma marginale str. St. Maries 3171807 YP_153682.1 CDS AM347 NC_004842.2 293135 296737 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(293135..296737) Anaplasma marginale str. St. Maries 3171844 YP_153683.1 CDS AM348 NC_004842.2 296823 297086 D hypothetical protein identified by Glimmer 2; hypothetical protein 296823..297086 Anaplasma marginale str. St. Maries 3171215 YP_153684.1 CDS coq7 NC_004842.2 297076 297588 D COG2941 CAT5 ubiquinone biosynthesis protein COQ7; ubiquinone biosynthesis protein 297076..297588 Anaplasma marginale str. St. Maries 3171829 YP_153685.1 CDS AM351 NC_004842.2 297645 298130 D hypothetical protein identified by Glimmer 2; hypothetical protein 297645..298130 Anaplasma marginale str. St. Maries 3171449 YP_153686.1 CDS AM354 NC_004842.2 298247 300946 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(298247..300946) Anaplasma marginale str. St. Maries 3170943 YP_153687.1 CDS AM356 NC_004842.2 301069 305679 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(301069..305679) Anaplasma marginale str. St. Maries 3171438 YP_153688.1 CDS AM357 NC_004842.2 305687 305917 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(305687..305917) Anaplasma marginale str. St. Maries 3171701 YP_153689.1 CDS AM359 NC_004842.2 306198 310316 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(306198..310316) Anaplasma marginale str. St. Maries 3171516 YP_153690.1 CDS AM360 NC_004842.2 310609 310893 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(310609..310893) Anaplasma marginale str. St. Maries 3171839 YP_153691.1 CDS AM366 NC_004842.2 311228 319747 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(311228..319747) Anaplasma marginale str. St. Maries 3171132 YP_153692.1 CDS AM368 NC_004842.2 320035 323076 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(320035..323076) Anaplasma marginale str. St. Maries 3171513 YP_153693.1 CDS uvrD NC_004842.2 323519 325534 R COG0210 UvrD superfamily I DNA and RNA helicases; DNA helicase II complement(323519..325534) Anaplasma marginale str. St. Maries 3171149 YP_153694.1 CDS AM371 NC_004842.2 325806 327449 D hypothetical protein identified by Glimmer 2; hypothetical protein 325806..327449 Anaplasma marginale str. St. Maries 3171094 YP_153695.1 CDS gyrA NC_004842.2 328606 331332 D negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 328606..331332 Anaplasma marginale str. St. Maries 3171304 YP_153696.1 CDS nth NC_004842.2 331332 331964 D COG0177 Nth predicted EndoIII-related endonuclease; endonuclease III 331332..331964 Anaplasma marginale str. St. Maries 3171035 YP_153697.1 CDS AM375 NC_004842.2 332283 332888 D hypothetical protein identified by Glimmer 2; hypothetical protein 332283..332888 Anaplasma marginale str. St. Maries 3171635 YP_153698.1 CDS htpG NC_004842.2 332974 334890 D molecular chaperone; heat shock protein 90 332974..334890 Anaplasma marginale str. St. Maries 3171358 YP_153699.1 CDS AM378 NC_004842.2 335136 335516 D hypothetical protein identified by Glimmer 2; hypothetical protein 335136..335516 Anaplasma marginale str. St. Maries 3171710 YP_153700.1 CDS AM380 NC_004842.2 335631 336011 D hypothetical protein identified by Glimmer 2; hypothetical protein 335631..336011 Anaplasma marginale str. St. Maries 3171869 YP_153701.1 CDS AM382 NC_004842.2 336686 337396 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(336686..337396) Anaplasma marginale str. St. Maries 3171287 YP_153702.1 CDS purB NC_004842.2 338112 339428 R Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase complement(338112..339428) Anaplasma marginale str. St. Maries 3171596 YP_153703.1 CDS uvrC NC_004842.2 340263 342104 D The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 340263..342104 Anaplasma marginale str. St. Maries 3171404 YP_153704.1 CDS AM387 NC_004842.2 342230 346690 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(342230..346690) Anaplasma marginale str. St. Maries 3171316 YP_153705.1 CDS birA NC_004842.2 347150 347878 R COG0340 BirA biotin-(acetyl-CoA carboxylase ligase); biotin-(acetyl-CoA carboxylase) complement(347150..347878) Anaplasma marginale str. St. Maries 3171299 YP_153706.1 CDS gst NC_004842.2 347887 348555 R COG0625 Gst glutathione-S-transferases; similar to NP_360419.1; glutathione S-transferase complement(347887..348555) Anaplasma marginale str. St. Maries 3171201 YP_153707.1 CDS AM391 NC_004842.2 348638 349180 R conserved hypothetical protein similar to BAA36355.1; hypothetical protein complement(348638..349180) Anaplasma marginale str. St. Maries 3171305 YP_153708.1 CDS AM392 NC_004842.2 349511 350587 D conserved family - ABC transporter; hypothetical protein 349511..350587 Anaplasma marginale str. St. Maries 3171548 YP_153709.1 CDS recR NC_004842.2 350796 351437 D involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 350796..351437 Anaplasma marginale str. St. Maries 3171790 YP_153710.1 CDS AM395 NC_004842.2 351434 351706 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(351434..351706) Anaplasma marginale str. St. Maries 3171032 YP_153711.1 CDS znuA NC_004842.2 351826 352710 R COG0803 ZnuA ABC-type Mn/Zn transport system periplasmic Mn/Zn-binding (lipo)protein (surface adhesin); similar to NP_541155.1; high-affinity zinc uptake system protein complement(351826..352710) Anaplasma marginale str. St. Maries 3171043 YP_153712.1 CDS znuC NC_004842.2 352690 353427 D COG1121 ZnuC ABC-type Mn/Zn transport systems ATPase component; similar to NP_759163.1; zinc ABC transporter ATP-binding protein 352690..353427 Anaplasma marginale str. St. Maries 3171813 YP_153713.1 CDS ubiB NC_004842.2 353420 354871 D COG0543 UbiB 2-polyprenylphenol hydroxylase; similar to NP_541211.1; ubiquinone biosynthesis protein 353420..354871 Anaplasma marginale str. St. Maries 3171536 YP_153714.1 CDS AM400 NC_004842.2 354909 356114 D conserved hypothetical protein similar to ZP_00210709.1; hypothetical protein 354909..356114 Anaplasma marginale str. St. Maries 3170997 YP_153715.1 CDS AM401 NC_004842.2 356277 357644 R conserved hypothetical protein similar to ZP_00142641.1; hypothetical protein complement(356277..357644) Anaplasma marginale str. St. Maries 3171615 YP_153716.1 CDS AM402 NC_004842.2 357781 360423 R conserved hypothetical protein similar to ZP_00210707.1; hypothetical protein complement(357781..360423) Anaplasma marginale str. St. Maries 3171009 YP_153717.1 CDS AM404 NC_004842.2 360719 361549 R conserved hypothetical protein similar to NP_966505.1; hypothetical protein complement(360719..361549) Anaplasma marginale str. St. Maries 3170950 YP_153718.1 CDS sucA NC_004842.2 361688 364480 D SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 361688..364480 Anaplasma marginale str. St. Maries 3171498 YP_153719.1 CDS AM406 NC_004842.2 365054 366205 R conserved family - phage major capsid protein; hypothetical protein complement(365054..366205) Anaplasma marginale str. St. Maries 3171494 YP_153720.1 CDS dapA NC_004842.2 366422 367327 R catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase complement(366422..367327) Anaplasma marginale str. St. Maries 3171207 YP_153721.1 CDS pkcI NC_004842.2 367524 367895 R protein kinase C inhibitor 1 (pkcI ); similar to EAA25530.1; protein kinase C inhibitor 1 complement(367524..367895) Anaplasma marginale str. St. Maries 3171736 YP_153722.1 CDS AM410 NC_004842.2 367892 369142 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(367892..369142) Anaplasma marginale str. St. Maries 3171026 YP_153723.1 CDS mutS NC_004842.2 369479 371938 D This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 369479..371938 Anaplasma marginale str. St. Maries 3171124 YP_153724.1 CDS AM413 NC_004842.2 371919 372203 D hypothetical protein identified by Glimmer 2; hypothetical protein 371919..372203 Anaplasma marginale str. St. Maries 3171756 YP_153725.1 CDS AM414 NC_004842.2 372351 373721 D conserved family - sugar and other transporter; high sequence identity to AM415, may be a duplicate gene; hypothetical protein 372351..373721 Anaplasma marginale str. St. Maries 3171213 YP_153726.1 CDS AM415 NC_004842.2 373831 375153 D conserved family - sugar and other transporter; high sequence identity to AM414, may be a duplicate gene; hypothetical protein 373831..375153 Anaplasma marginale str. St. Maries 3171004 YP_153727.1 CDS nadE NC_004842.2 375143 376663 R COG0171 NadE NAD synthase; NH3-dependent NAD+ synthetase protein complement(375143..376663) Anaplasma marginale str. St. Maries 3171122 YP_153728.1 CDS hemB NC_004842.2 376670 377710 R catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase complement(376670..377710) Anaplasma marginale str. St. Maries 3171077 YP_153729.1 CDS pbpA2 NC_004842.2 377907 379496 D COG0768 FtsI cell division protein FtsI/penicillin-binding protein 2; penicillin-binding protein 377907..379496 Anaplasma marginale str. St. Maries 3171395 YP_153730.1 CDS AM419 NC_004842.2 379536 382376 D conserved hypothetical protein similar to ZP_00210697.1; hypothetical protein 379536..382376 Anaplasma marginale str. St. Maries 3171808 YP_153731.1 CDS AM420 NC_004842.2 382538 384001 D conserved family - permease of the major facilitator superfamily; hypothetical protein 382538..384001 Anaplasma marginale str. St. Maries 3171382 YP_153732.1 CDS ssb NC_004842.2 384373 384912 R COG0629 Ssb single-stranded DNA-binding protein; similar to NP_771338.1; single-strand binding protein complement(384373..384912) Anaplasma marginale str. St. Maries 3171114 YP_153733.1 CDS mcd NC_004842.2 385083 386465 D malonyl-CoA decarboxylase 385083..386465 Anaplasma marginale str. St. Maries 3170973 YP_153734.1 CDS gatB NC_004842.2 386478 387935 D allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 386478..387935 Anaplasma marginale str. St. Maries 3171857 YP_153735.1 CDS fabI NC_004842.2 388435 389283 D COG0623 FabI enoyl-[ACP] reductase (NADH); similar to NP_385004.1; enoyl-[ACP] reductase 388435..389283 Anaplasma marginale str. St. Maries 3171150 YP_153736.1 CDS dnaA NC_004842.2 389525 390940 D binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 389525..390940 Anaplasma marginale str. St. Maries 3171543 YP_153737.1 CDS AM431 NC_004842.2 391044 392039 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(391044..392039) Anaplasma marginale str. St. Maries 3171419 YP_153738.1 CDS AM432 NC_004842.2 392119 392823 D conserved family - nicotinic acid mononucleotide adenylyltransferase; hypothetical protein 392119..392823 Anaplasma marginale str. St. Maries 3170948 YP_153739.1 CDS pdxJ NC_004842.2 393003 393764 D involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 393003..393764 Anaplasma marginale str. St. Maries 3171900 YP_153740.1 CDS AM435 NC_004842.2 394935 395825 R conserved family - DNA polymerase III subunit; hypothetical protein complement(394935..395825) Anaplasma marginale str. St. Maries 3171519 YP_153741.1 CDS AM436 NC_004842.2 395807 396400 R conserved hypothetical protein similar to ZP_00210684.1; hypothetical protein complement(395807..396400) Anaplasma marginale str. St. Maries 3171540 YP_153742.1 CDS coaE NC_004842.2 397133 397849 D COG0237 CoaE dephospho-CoA kinase; dephospho-CoA kinase 397133..397849 Anaplasma marginale str. St. Maries 3171571 YP_153743.1 CDS thiC NC_004842.2 397898 399700 R required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC complement(397898..399700) Anaplasma marginale str. St. Maries 3171678 YP_153744.1 CDS AM441 NC_004842.2 399744 400409 R conserved hypothetical protein similar to ZP_00210681.1; hypothetical protein complement(399744..400409) Anaplasma marginale str. St. Maries 3171067 YP_153745.1 CDS rpoZ NC_004842.2 400474 400860 R COG1758 RpoZ DNA-directed RNA polymerase subunit K/omega; DNA-directed RNA polymerase subunit omega complement(400474..400860) Anaplasma marginale str. St. Maries 3171461 YP_153746.1 CDS AM445 NC_004842.2 401195 401518 R conserved hypothetical protein similar to ZP_00210679.1; hypothetical protein complement(401195..401518) Anaplasma marginale str. St. Maries 3171405 YP_153747.1 CDS leuS NC_004842.2 401901 404390 D leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 401901..404390 Anaplasma marginale str. St. Maries 3171345 YP_153748.1 CDS AM447 NC_004842.2 404701 405489 D conserved family - Mg-dependent DNase; hypothetical protein 404701..405489 Anaplasma marginale str. St. Maries 3171926 YP_153749.1 CDS pyrF NC_004842.2 405446 406165 D COG0284 PyrF orotidine-5'-phosphate decarboxylase; orotidine 5'-phosphate decarboxylase 405446..406165 Anaplasma marginale str. St. Maries 3171631 YP_153750.1 CDS ccmE NC_004842.2 406258 406680 R CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome C maturation system; periplasmic protein anchored to the inner membrane; cytochrome C-type biogenesis protein CcmE complement(406258..406680) Anaplasma marginale str. St. Maries 3171916 YP_153751.1 CDS surE NC_004842.2 406802 407587 R COG0496 SurE survival protein, predicted acid phosphatase; stationary-phase survival protein complement(406802..407587) Anaplasma marginale str. St. Maries 3170996 YP_153752.1 CDS nuoC1 NC_004842.2 408316 408879 R COG0852 NuoC NADH:ubiquinone oxidoreductase 27 kD subunit; NADH-ubiquinone oxidoreductase subunit complement(408316..408879) Anaplasma marginale str. St. Maries 3171394 YP_153753.1 CDS nuoB NC_004842.2 408885 409412 R The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B complement(408885..409412) Anaplasma marginale str. St. Maries 3171030 YP_153754.1 CDS nuoA NC_004842.2 409417 409824 R COG0838 NuoA NADH:ubiquinone oxidoreductase subunit 3 (chain A); NADH dehydrogenase I subunit A complement(409417..409824) Anaplasma marginale str. St. Maries 3171709 YP_153755.1 CDS uvrA NC_004842.2 410141 413011 R COG0178 UvrA excinuclease ATPase subunit; excinuclease ABC subunit A complement(410141..413011) Anaplasma marginale str. St. Maries 3170994 YP_153756.1 CDS nusB NC_004842.2 413045 413578 R COG0781 NusB transcription termination factor; N utilization substance protein B complement(413045..413578) Anaplasma marginale str. St. Maries 3171780 YP_153757.2 CDS ribH NC_004842.2 413571 414020 R RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase complement(413571..414020) Anaplasma marginale str. St. Maries 3171837 YP_153758.2 CDS yidC NC_004842.2 414052 415770 R functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC complement(414052..415770) Anaplasma marginale str. St. Maries 3171335 YP_153759.1 CDS pssA NC_004842.2 416086 416928 R COG1183 PssA phosphatidylserine synthase; CDP-diacylglycerol--serine O-phosphatidyltransferase complement(416086..416928) Anaplasma marginale str. St. Maries 3171748 YP_153760.1 CDS psd NC_004842.2 416989 417693 R catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase complement(416989..417693) Anaplasma marginale str. St. Maries 3171333 YP_153761.1 CDS AM465 NC_004842.2 417952 421353 R conserved hypothetical protein similar to NP_840932.1; hypothetical protein complement(417952..421353) Anaplasma marginale str. St. Maries 3171047 YP_153762.1 CDS AM470 NC_004842.2 421771 425556 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(421771..425556) Anaplasma marginale str. St. Maries 3171864 YP_153763.1 CDS murG NC_004842.2 425738 426856 D COG0707 MurG UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; similar to NP_421354.1; UDP-N-acetylglucosamine-N-acetylmuramyl- (pentapeptide pyrophosphoryl-undecaprenol N-acetylglucosamine) 425738..426856 Anaplasma marginale str. St. Maries 3171244 YP_153764.1 CDS efp NC_004842.2 427002 427568 D COG0231 Efp translation elongation factor P; translation initiation factor eIF-5A; elongation factor PEF-P 427002..427568 Anaplasma marginale str. St. Maries 3171738 YP_153765.1 CDS suhB NC_004842.2 427571 428332 D COG0483 SuhB Archaeal fructose-1,6-bisphosphatase and related enzymes of; similar to NP_104922.1; extragenic suppressor protein 427571..428332 Anaplasma marginale str. St. Maries 3171082 YP_153766.1 CDS rluC NC_004842.2 428329 429219 D COG0564 RluA pseudouridylate synthases, 23S RNA-specific; ribosomal large subunit pseudouridine synthase 428329..429219 Anaplasma marginale str. St. Maries 3171427 YP_153767.1 CDS pleD NC_004842.2 429469 430836 R involved in swarmer-to-stalked cell differentiation in Caulobacter crescentus; catalyzes the condensation of two GTP molecules to form the secondary messenger cyclic di-GMP (c-di-GMP); upon phosphorylation of domain D1 the protein dimerizes; presumably this allows the two GTP-bound GGDEF (diguanylate cyclase) domains to catalyze the condensation reaction; allosterically inhibited by c-di-GMP; response regulator PleD complement(429469..430836) Anaplasma marginale str. St. Maries 3171125 YP_153768.1 CDS AM476 NC_004842.2 431033 431419 R conserved hypothetical protein similar to ZP_00210656.1; hypothetical protein complement(431033..431419) Anaplasma marginale str. St. Maries 3170988 YP_153769.1 CDS AM477 NC_004842.2 431385 436238 R conserved family - NAD-specific glutamate dehydrogenase; hypothetical protein complement(431385..436238) Anaplasma marginale str. St. Maries 3171254 YP_153770.1 CDS AM480 NC_004842.2 436634 437359 D conserved hypothetical protein similar to ZP_00210654.1; hypothetical protein 436634..437359 Anaplasma marginale str. St. Maries 3171161 YP_153771.1 CDS cysS NC_004842.2 437361 438761 D catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 437361..438761 Anaplasma marginale str. St. Maries 3171872 YP_153772.1 CDS nrdF NC_004842.2 439009 439983 D B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 439009..439983 Anaplasma marginale str. St. Maries 3171897 YP_153773.1 CDS AM485 NC_004842.2 439961 440560 D conserved family - thiol:disulfide interchange protein; hypothetical protein 439961..440560 Anaplasma marginale str. St. Maries 3171016 YP_153774.1 CDS AM486 NC_004842.2 441151 441435 R conserved hypothetical protein similar to ZP_00210650.1; hypothetical protein complement(441151..441435) Anaplasma marginale str. St. Maries 3171803 YP_153775.1 CDS AM487 NC_004842.2 441651 442682 D conserved hypothetical protein similar to ZP_00210648.1; hypothetical protein 441651..442682 Anaplasma marginale str. St. Maries 3171459 YP_153776.1 CDS dnaG NC_004842.2 442810 444648 D COG0358 DnaG DNA primase (bacterial type); similar to NP_539447.1; DNA primase 442810..444648 Anaplasma marginale str. St. Maries 3171158 YP_153777.1 CDS AM489 NC_004842.2 444617 444838 D hypothetical protein identified by Glimmer 2; hypothetical protein 444617..444838 Anaplasma marginale str. St. Maries 3171011 YP_153778.1 CDS rpoD NC_004842.2 444813 446711 R COG0568 RpoD DNA-directed RNA polymerase sigma subunits (sigma70/sigma32); RNA polymerase sigma factor complement(444813..446711) Anaplasma marginale str. St. Maries 3171104 YP_153779.1 CDS AM492 NC_004842.2 446914 447876 R conserved family - nifR3 like protein; hypothetical protein complement(446914..447876) Anaplasma marginale str. St. Maries 3171834 YP_153780.1 CDS ispE NC_004842.2 448016 448885 D An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 448016..448885 Anaplasma marginale str. St. Maries 3171840 YP_153781.1 CDS AM495 NC_004842.2 449010 449444 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(449010..449444) Anaplasma marginale str. St. Maries 3171831 YP_153782.1 CDS cutA NC_004842.2 449860 450216 R COG1324 CutA uncharacterized protein involved in tolerance to divalent cations; divalent cation tolerance protein complement(449860..450216) Anaplasma marginale str. St. Maries 3171866 YP_153783.1 CDS dhkA NC_004842.2 450260 452743 R sensory box histidine kinase/response regulator complement(450260..452743) Anaplasma marginale str. St. Maries 3171257 YP_153784.1 CDS AM499 NC_004842.2 453242 453904 R conserved family - O-methyltransferase; hypothetical protein complement(453242..453904) Anaplasma marginale str. St. Maries 3171374 YP_153785.1 CDS AM500 NC_004842.2 454148 454468 D conserved hypothetical protein similar to ZP_00210640.1; hypothetical protein 454148..454468 Anaplasma marginale str. St. Maries 3171500 YP_153786.1 CDS AM501 NC_004842.2 454671 456080 D conserved family - predicted sugar kinase; hypothetical protein 454671..456080 Anaplasma marginale str. St. Maries 3171284 YP_153787.1 CDS topA NC_004842.2 456208 458646 D COG0550 TopA topoisomerase IA; DNA topoisomerase 456208..458646 Anaplasma marginale str. St. Maries 3171572 YP_153788.1 CDS AM504 NC_004842.2 458866 459342 R conserved hypothetical protein similar to ZP_00210636.1; hypothetical protein complement(458866..459342) Anaplasma marginale str. St. Maries 3171873 YP_153789.1 CDS acpS NC_004842.2 460409 460771 R Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase complement(460409..460771) Anaplasma marginale str. St. Maries 3171551 YP_153790.1 CDS proS NC_004842.2 460768 462045 R catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase complement(460768..462045) Anaplasma marginale str. St. Maries 3171578 YP_153791.1 CDS AM508 NC_004842.2 462309 463361 R conserved hypothetical protein similar to NP_966301.1; hypothetical protein complement(462309..463361) Anaplasma marginale str. St. Maries 3171798 YP_153792.1 CDS coaD NC_004842.2 463648 464160 D Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 463648..464160 Anaplasma marginale str. St. Maries 3171036 YP_153793.1 CDS trxB NC_004842.2 464331 465308 R COG0492 TrxB thioredoxin reductase; thioredoxin reductase complement(464331..465308) Anaplasma marginale str. St. Maries 3171507 YP_153794.1 CDS tdpX1 NC_004842.2 465305 465928 R COG0450 AhpC peroxiredoxin; similar to NP_360088.1; thioredoxin peroxidase 1 complement(465305..465928) Anaplasma marginale str. St. Maries 3171741 YP_153795.1 CDS aatA NC_004842.2 466204 466884 D COG0075 serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; open reading frame split domain with AM515; aspartate aminotransferase A 466204..466884 Anaplasma marginale str. St. Maries 3171570 YP_153796.1 CDS aatA NC_004842.2 466941 467561 D COG0075 serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; open reading frame split domain with AM514; aspartate aminotransferase A 466941..467561 Anaplasma marginale str. St. Maries 3171331 YP_153797.1 CDS AM516 NC_004842.2 467807 469819 R conserved family - peptidyl-prolyl cis-trans isomerase D; hypothetical protein complement(467807..469819) Anaplasma marginale str. St. Maries 3171558 YP_153798.1 CDS AM517 NC_004842.2 469871 470464 R conserved hypothetical protein similar to NP_384508.1; hypothetical protein complement(469871..470464) Anaplasma marginale str. St. Maries 3171865 YP_153799.1 CDS AM518 NC_004842.2 470483 471793 R conserved family - transporter protein; hypothetical protein complement(470483..471793) Anaplasma marginale str. St. Maries 3171359 YP_153800.1 CDS AM520 NC_004842.2 471817 473121 R conserved family - transporter protein; hypothetical protein complement(471817..473121) Anaplasma marginale str. St. Maries 3171086 YP_153801.1 CDS mreC NC_004842.2 473383 474249 D in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 473383..474249 Anaplasma marginale str. St. Maries 3171529 YP_153802.1 CDS mreB NC_004842.2 474358 475467 R functions in MreBCD complex in some organisms; rod shape-determining protein MreB complement(474358..475467) Anaplasma marginale str. St. Maries 3171463 YP_153803.1 CDS truB NC_004842.2 475701 476621 D COG0130 TruB pseudouridine synthase; tRNA pseudouridine 55 synthase 475701..476621 Anaplasma marginale str. St. Maries 3171734 YP_153804.1 CDS rpsO NC_004842.2 476660 476941 D primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 476660..476941 Anaplasma marginale str. St. Maries 3171814 YP_153805.1 CDS pnp NC_004842.2 476993 479410 D COG0005 Pnp purine nucleoside phosphorylase; similar to NP_384350.1; polynucleotide phosphorylase/polyadenylase 476993..479410 Anaplasma marginale str. St. Maries 3171743 YP_153806.1 CDS AM527 NC_004842.2 479416 480192 D conserved hypothetical protein similar to NP_419648.1; hypothetical protein 479416..480192 Anaplasma marginale str. St. Maries 3171628 YP_153807.1 CDS lepA NC_004842.2 480327 482126 D binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 480327..482126 Anaplasma marginale str. St. Maries 3171773 YP_153808.1 CDS AM529 NC_004842.2 483114 483482 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(483114..483482) Anaplasma marginale str. St. Maries 3171373 YP_153809.1 CDS msp1a NC_004842.2 483889 485769 D member of msp1 superfamily; major surface protein 1a 483889..485769 Anaplasma marginale str. St. Maries 3171757 YP_153810.1 CDS mlp2 NC_004842.2 486324 487166 D major surface protein 1a-like protein 22 486324..487166 Anaplasma marginale str. St. Maries 3171135 YP_153811.1 CDS mlp3 NC_004842.2 487640 488515 D major surface protein 1a-like protein 3 487640..488515 Anaplasma marginale str. St. Maries 3171704 YP_153812.1 CDS mlp4 NC_004842.2 488938 489873 D major surface protein 1a-like protein 4 488938..489873 Anaplasma marginale str. St. Maries 3171541 YP_153813.1 CDS AM537 NC_004842.2 489895 490626 D hypothetical protein identified by Glimmer 2; hypothetical protein 489895..490626 Anaplasma marginale str. St. Maries 3171266 YP_153814.1 CDS AM540 NC_004842.2 491451 498992 D hypothetical protein identified by Glimmer 2; hypothetical protein 491451..498992 Anaplasma marginale str. St. Maries 3171910 YP_153815.1 CDS AM541 NC_004842.2 499054 500883 D hypothetical protein identified by Glimmer 2; hypothetical protein 499054..500883 Anaplasma marginale str. St. Maries 3171034 YP_153816.1 CDS AM543 NC_004842.2 501283 503181 D hypothetical protein identified by Glimmer 2; hypothetical protein 501283..503181 Anaplasma marginale str. St. Maries 3171253 YP_153817.1 CDS AM545 NC_004842.2 503759 505636 D hypothetical protein identified by Glimmer 2; hypothetical protein 503759..505636 Anaplasma marginale str. St. Maries 3171890 YP_153818.1 CDS AM546 NC_004842.2 505658 505891 D hypothetical protein identified by Glimmer 2; hypothetical protein 505658..505891 Anaplasma marginale str. St. Maries 3171239 YP_153819.1 CDS AM547 NC_004842.2 506074 507987 D hypothetical protein identified by Glimmer 2; hypothetical protein 506074..507987 Anaplasma marginale str. St. Maries 3171758 YP_153820.1 CDS AM550 NC_004842.2 508787 510619 D hypothetical protein identified by Glimmer 2; hypothetical protein 508787..510619 Anaplasma marginale str. St. Maries 3171448 YP_153821.1 CDS AM551 NC_004842.2 510801 512963 D hypothetical protein identified by Glimmer 2; hypothetical protein 510801..512963 Anaplasma marginale str. St. Maries 3171930 YP_153822.1 CDS thiL NC_004842.2 512951 513904 R COG0611 ThiL thiamine monophosphate kinase; similar to NP_439456.1; thiamin-monophosphate kinase complement(512951..513904) Anaplasma marginale str. St. Maries 3171581 YP_153823.1 CDS AM555 NC_004842.2 514140 515027 D conserved family - ribonuclease BN; hypothetical protein 514140..515027 Anaplasma marginale str. St. Maries 3171706 YP_153824.1 CDS bioA NC_004842.2 515209 516492 D COG0161 adenosylmethionine-8-amino-7-oxononanoate; similar to ZP_00210585.1; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 515209..516492 Anaplasma marginale str. St. Maries 3171796 YP_153825.1 CDS AM557 NC_004842.2 516933 517268 D conserved hypothetical protein similar to ZP_00210612.1; hypothetical protein 516933..517268 Anaplasma marginale str. St. Maries 3171693 YP_153826.1 CDS ksgA NC_004842.2 517430 518242 R catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase complement(517430..518242) Anaplasma marginale str. St. Maries 3171102 YP_153827.1 CDS tpiA NC_004842.2 518375 519181 D Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 518375..519181 Anaplasma marginale str. St. Maries 3171314 YP_153828.1 CDS AM560 NC_004842.2 519165 520184 D conserved family - cell surface protein; hypothetical protein 519165..520184 Anaplasma marginale str. St. Maries 3171413 YP_153829.1 CDS AM561 NC_004842.2 520194 521219 D in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 520194..521219 Anaplasma marginale str. St. Maries 3171200 YP_153830.1 CDS AM562 NC_004842.2 521178 521828 R conserved family - predicted membrane; hypothetical protein complement(521178..521828) Anaplasma marginale str. St. Maries 3171242 YP_153831.1 CDS folB NC_004842.2 521880 522233 D COG1539 FolB dihydroneopterin aldolase; dihydroneopterin aldolase 521880..522233 Anaplasma marginale str. St. Maries 3170999 YP_153832.1 CDS mdh NC_004842.2 522285 523238 D Catalyzes the reversible oxidation of malate to oxaloacetate; malate dehydrogenase 522285..523238 Anaplasma marginale str. St. Maries 3171816 YP_153833.1 CDS ubiG NC_004842.2 523554 524231 R Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase complement(523554..524231) Anaplasma marginale str. St. Maries 3170965 YP_153834.1 CDS infB NC_004842.2 524186 524755 D COG0532 translation initiation factor 2 (GTPase); translation initiation factor IF-2 524186..524755 Anaplasma marginale str. St. Maries 3171476 YP_153835.1 CDS AM569 NC_004842.2 524724 524966 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(524724..524966) Anaplasma marginale str. St. Maries 3171648 YP_153836.1 CDS rpiB NC_004842.2 525159 525599 D COG0698 ribose 5-phosphate isomerase; similar to ZP_00210562.1; ribose 5-phosphate isomerase 525159..525599 Anaplasma marginale str. St. Maries 3171754 YP_153837.1 CDS ubiG NC_004842.2 525692 526396 D Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 525692..526396 Anaplasma marginale str. St. Maries 3171835 YP_153838.1 CDS gcp NC_004842.2 526497 527003 R similar to NP_533316.1; O-sialoglycoprotein endopeptidase complement(526497..527003) Anaplasma marginale str. St. Maries 3171842 YP_153839.1 CDS AM573 NC_004842.2 527013 527219 R conserved hypothetical protein similar to AAL08810.1; hypothetical protein complement(527013..527219) Anaplasma marginale str. St. Maries 3171453 YP_153840.1 CDS AM574 NC_004842.2 527461 528138 R conserved hypothetical protein similar to ZP_00210584.1; hypothetical protein complement(527461..528138) Anaplasma marginale str. St. Maries 3171806 YP_153841.1 CDS AM576 NC_004842.2 528119 528949 R conserved hypothetical protein similar to ZP_00210584.1; hypothetical protein complement(528119..528949) Anaplasma marginale str. St. Maries 3171898 YP_153842.1 CDS AM578 NC_004842.2 528928 529647 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(528928..529647) Anaplasma marginale str. St. Maries 3171776 YP_153843.1 CDS AM579 NC_004842.2 529698 530105 R conserved hypothetical protein similar to ZP_00210581.1; hypothetical protein complement(529698..530105) Anaplasma marginale str. St. Maries 3171788 YP_153844.1 CDS AM580 NC_004842.2 530080 530466 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(530080..530466) Anaplasma marginale str. St. Maries 3171399 YP_153845.1 CDS AM581 NC_004842.2 530463 531017 R conserved hypothetical protein similar to ZP_00210579.1; hypothetical protein complement(530463..531017) Anaplasma marginale str. St. Maries 3171238 YP_153846.1 CDS AM582 NC_004842.2 531026 531367 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(531026..531367) Anaplasma marginale str. St. Maries 3171109 YP_153847.1 CDS putA NC_004842.2 531869 535012 R proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase complement(531869..535012) Anaplasma marginale str. St. Maries 3171262 YP_153848.1 CDS fabG NC_004842.2 535097 536005 D COG1028 FabG dehydrogenases with different specificities (related to short-chain alcohol); similar to NP_360820.1; 3-oxoacyl-ACP reductase 535097..536005 Anaplasma marginale str. St. Maries 3171250 YP_153849.1 CDS AM586 NC_004842.2 536059 536391 R conserved family - proline dehydrogenase; hypothetical protein complement(536059..536391) Anaplasma marginale str. St. Maries 3171119 YP_153850.1 CDS AM589 NC_004842.2 537408 538310 D hypothetical protein identified by Glimmer 2; hypothetical protein 537408..538310 Anaplasma marginale str. St. Maries 3171753 YP_153851.1 CDS rlpA NC_004842.2 538467 539162 R COG0797 RlpA lipoproteins; similar to NP_220771.1; rare lipoprotein A complement(538467..539162) Anaplasma marginale str. St. Maries 3171177 YP_153852.1 CDS xthA2 NC_004842.2 539361 540191 R COG0708 XthA exonuclease III; similar to NP_360665.1; exodeoxyribonuclease III complement(539361..540191) Anaplasma marginale str. St. Maries 3171163 YP_153853.1 CDS AM592 NC_004842.2 540314 541048 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(540314..541048) Anaplasma marginale str. St. Maries 3171742 YP_153854.1 CDS rpmJ NC_004842.2 541381 541500 D COG0257 RpmJ ribosomal protein L36; large subunit ribosomal protein L36 541381..541500 Anaplasma marginale str. St. Maries 3171444 YP_153855.1 CDS AM594 NC_004842.2 541529 541888 D hypothetical protein identified by Glimmer 2; hypothetical protein 541529..541888 Anaplasma marginale str. St. Maries 3171561 YP_153856.1 CDS AM595 NC_004842.2 541901 542551 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(541901..542551) Anaplasma marginale str. St. Maries 3171602 YP_153857.1 CDS rpmA NC_004842.2 542576 542848 R involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 complement(542576..542848) Anaplasma marginale str. St. Maries 3171746 YP_153858.2 CDS rplU NC_004842.2 542852 543154 R COG0261 RplU ribosomal protein L21; 50S ribosomal protein L21 complement(542852..543154) Anaplasma marginale str. St. Maries 3171255 YP_153859.1 CDS eno NC_004842.2 543637 544932 D enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 543637..544932 Anaplasma marginale str. St. Maries 3171423 YP_153860.1 CDS obgE NC_004842.2 544934 545980 D essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 544934..545980 Anaplasma marginale str. St. Maries 3171722 YP_153861.1 CDS AM603 NC_004842.2 545943 546332 D hypothetical protein identified by Glimmer 2; hypothetical protein 545943..546332 Anaplasma marginale str. St. Maries 3171259 YP_153862.1 CDS mraW NC_004842.2 546503 547378 R S-adenosyl-methyltransferase; similar to NP_773250.1; S-adenosyl-methyltransferase complement(546503..547378) Anaplasma marginale str. St. Maries 3171309 YP_153863.1 CDS ygfA NC_004842.2 547550 548086 R COG0212 5-formyltetrahydrofolate cyclo-ligase; similar to ZP_00210813.1; 5-formyltetrahydrofolate cyclo-ligase complement(547550..548086) Anaplasma marginale str. St. Maries 3171123 YP_153864.1 CDS AM612 NC_004842.2 548370 553613 D hypothetical protein identified by Glimmer 2; hypothetical protein 548370..553613 Anaplasma marginale str. St. Maries 3171400 YP_153865.1 CDS AM613 NC_004842.2 553836 555356 D hypothetical protein identified by Glimmer 2; hypothetical protein 553836..555356 Anaplasma marginale str. St. Maries 3171861 YP_153866.1 CDS AM615 NC_004842.2 555884 556453 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(555884..556453) Anaplasma marginale str. St. Maries 3171856 YP_153867.1 CDS AM616 NC_004842.2 556586 558397 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(556586..558397) Anaplasma marginale str. St. Maries 3170968 YP_153868.1 CDS trxB2 NC_004842.2 558602 559624 R COG0492 TrxB thioredoxin reductase; similar to NP_360274.1; thioredoxin reductase complement(558602..559624) Anaplasma marginale str. St. Maries 3171421 YP_153869.1 CDS pmbA NC_004842.2 559705 561039 R COG0312 TldD predicted Zn-dependent proteases and their inactivated homologs; similar to NP_774159.1; pmbA protein complement(559705..561039) Anaplasma marginale str. St. Maries 3171501 YP_153870.1 CDS folE NC_004842.2 561049 561645 R COG0302 FolE GTP cyclohydrolase I; GTP cyclohydrolase complement(561049..561645) Anaplasma marginale str. St. Maries 3171606 YP_153871.1 CDS atpG NC_004842.2 561652 562515 R COG0224 AtpG F0F1-type ATP synthase subunit gamma; ATP synthase subunit gamma complement(561652..562515) Anaplasma marginale str. St. Maries 3171384 YP_153872.1 CDS nuoD NC_004842.2 562810 564006 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 562810..564006 Anaplasma marginale str. St. Maries 3171138 YP_153873.1 CDS nuoE NC_004842.2 564011 564520 D Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 564011..564520 Anaplasma marginale str. St. Maries 3171051 YP_153874.1 CDS dnaQ NC_004842.2 564510 565208 D COG0847 DnaQ DNA polymerase III epsilon subunit and related 3'-5' exonucleases; similar to NP_418825.1; DNA polymerase III subunit epsilon 564510..565208 Anaplasma marginale str. St. Maries 3171533 YP_153875.1 CDS AM626 NC_004842.2 565245 566825 R conserved hypothetical protein similar to NP_966479.1; hypothetical protein complement(565245..566825) Anaplasma marginale str. St. Maries 3171896 YP_153876.1 CDS AM628 NC_004842.2 567191 567829 D hypothetical protein identified by Glimmer 2; hypothetical protein 567191..567829 Anaplasma marginale str. St. Maries 3171854 YP_153877.1 CDS AM629 NC_004842.2 568265 570115 D hypothetical protein identified by Glimmer 2; hypothetical protein 568265..570115 Anaplasma marginale str. St. Maries 3171647 YP_153878.1 CDS AM630 NC_004842.2 570249 570782 R conserved hypothetical protein similar to NP_966787.1; hypothetical protein complement(570249..570782) Anaplasma marginale str. St. Maries 3171066 YP_153879.1 CDS rpoH NC_004842.2 570776 571648 R COG0568 RpoD DNA-directed RNA polymerase sigma subunits (sigma70/sigma32); similar to NP_421892.1; RNA polymerase sigma-32 factor complement(570776..571648) Anaplasma marginale str. St. Maries 3171263 YP_153880.1 CDS AM632 NC_004842.2 571770 572084 D conserved hypothetical protein similar to ZP_00210576.1; hypothetical protein 571770..572084 Anaplasma marginale str. St. Maries 3171712 YP_153881.1 CDS AM634 NC_004842.2 572081 572326 D hypothetical protein identified by Glimmer 2; hypothetical protein 572081..572326 Anaplasma marginale str. St. Maries 3171538 YP_153882.1 CDS AM638 NC_004842.2 572766 582350 D hypothetical protein identified by Glimmer 2; hypothetical protein 572766..582350 Anaplasma marginale str. St. Maries 3171745 YP_153883.1 CDS nuoH NC_004842.2 582496 583554 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H complement(582496..583554) Anaplasma marginale str. St. Maries 3171010 YP_153884.1 CDS nuoG NC_004842.2 583556 585631 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G complement(583556..585631) Anaplasma marginale str. St. Maries 3171653 YP_153885.1 CDS AM642 NC_004842.2 585639 585854 R conserved hypothetical protein similar to ZP_00210543.1; hypothetical protein complement(585639..585854) Anaplasma marginale str. St. Maries 3171172 YP_153886.1 CDS gyrB2 NC_004842.2 586035 588416 R COG0187 GyrB DNA gyrase (topoisomerase II) B subunit; DNA gyrase subunit B complement(586035..588416) Anaplasma marginale str. St. Maries 3171889 YP_153887.1 CDS ubiX NC_004842.2 588750 589355 D COG0163 UbiX 3-polyprenyl-4-hydroxybenzoate decarboxylase; similar to NP_360438.1; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 588750..589355 Anaplasma marginale str. St. Maries 3171107 YP_153888.1 CDS AM647 NC_004842.2 589454 589879 R conserved hypothetical protein similar to ZP_00210560.1; hypothetical protein complement(589454..589879) Anaplasma marginale str. St. Maries 3171008 YP_153889.1 CDS AM649 NC_004842.2 590379 591602 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(590379..591602) Anaplasma marginale str. St. Maries 3171100 YP_153890.1 CDS adx1 NC_004842.2 591574 591927 R COG0633 Fdx ferredoxin; similar to NP_220587.1; ferredoxin [2Fe-2S] adrenodoxin-like precursor adx1 complement(591574..591927) Anaplasma marginale str. St. Maries 3171544 YP_153891.1 CDS hscA NC_004842.2 591953 593761 R COG0443 DnaK molecular chaperone; heat shock protein complement(591953..593761) Anaplasma marginale str. St. Maries 3171306 YP_153892.1 CDS hscB NC_004842.2 593749 594297 R COG1076 DjlA DnaJ-domain-containing proteins 1; similar to NP_359900.1; chaperone protein complement(593749..594297) Anaplasma marginale str. St. Maries 3171411 YP_153893.1 CDS nifU NC_004842.2 594578 594979 R COG0822 IscU NifU homologs involved in Fe-S cluster formation; scaffold protein complement(594578..594979) Anaplasma marginale str. St. Maries 3171307 YP_153894.1 CDS iscS NC_004842.2 594988 596214 R catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase complement(594988..596214) Anaplasma marginale str. St. Maries 3171143 YP_153895.1 CDS AM656 NC_004842.2 596247 597809 R conserved family - aminotransferase; hypothetical protein complement(596247..597809) Anaplasma marginale str. St. Maries 3171643 YP_153896.1 CDS AM657 NC_004842.2 598007 598711 D conserved family - hydrolase; hypothetical protein 598007..598711 Anaplasma marginale str. St. Maries 3171677 YP_153897.1 CDS lysK NC_004842.2 599013 600614 D class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine; lysyl-tRNA synthetase 599013..600614 Anaplasma marginale str. St. Maries 3171527 YP_153898.1 CDS AM660 NC_004842.2 600760 601101 D conserved hypothetical protein similar to ZP_00210549.1; hypothetical protein 600760..601101 Anaplasma marginale str. St. Maries 3171218 YP_153899.1 CDS truA NC_004842.2 601147 601890 R mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A complement(601147..601890) Anaplasma marginale str. St. Maries 3171862 YP_153900.1 CDS pyrB NC_004842.2 601887 602783 R catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit complement(601887..602783) Anaplasma marginale str. St. Maries 3171391 YP_153901.1 CDS AM664 NC_004842.2 602946 603605 R similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; translaldolase complement(602946..603605) Anaplasma marginale str. St. Maries 3171083 YP_153902.1 CDS atpC NC_004842.2 603602 603988 R COG0355 AtpC F0F1-type ATP synthase epsilon subunit (mitochondrial delta subunit); ATP synthase subunit epsilon complement(603602..603988) Anaplasma marginale str. St. Maries 3171685 YP_153903.1 CDS atpD NC_004842.2 604058 605518 R Produces ATP from ADP in the presence of a proton gradient across the membrane. The subunit beta is a regulatory subunit; F0F1 ATP synthase subunit beta complement(604058..605518) Anaplasma marginale str. St. Maries 3171682 YP_153904.1 CDS mgtE NC_004842.2 605894 607345 D COG2239 MgtE Mg/Co/Ni transporter MgtE (contains CBS domain); magnesium transporter 605894..607345 Anaplasma marginale str. St. Maries 3171699 YP_153905.1 CDS ftsJ NC_004842.2 607824 608429 D COG0293 FtsJ methyltransferase involved in cell division; similar to NP_108462.1; cell division protein 607824..608429 Anaplasma marginale str. St. Maries 3171386 YP_153906.1 CDS AM670 NC_004842.2 608913 609782 D hypothetical protein identified by Glimmer 2; hypothetical protein 608913..609782 Anaplasma marginale str. St. Maries 3171197 YP_153907.1 CDS AM671 NC_004842.2 609843 610784 D hypothetical protein identified by Glimmer 2; hypothetical protein 609843..610784 Anaplasma marginale str. St. Maries 3171645 YP_153908.1 CDS AM673 NC_004842.2 611370 612968 D hypothetical protein identified by Glimmer 2; hypothetical protein 611370..612968 Anaplasma marginale str. St. Maries 3171232 YP_153909.1 CDS AM675 NC_004842.2 613573 616785 D hypothetical protein identified by Glimmer 2; hypothetical protein 613573..616785 Anaplasma marginale str. St. Maries 3171496 YP_153910.1 CDS AM676 NC_004842.2 617089 618480 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(617089..618480) Anaplasma marginale str. St. Maries 3171281 YP_153911.1 CDS argS NC_004842.2 618649 620388 R catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase complement(618649..620388) Anaplasma marginale str. St. Maries 3171804 YP_153912.1 CDS recO NC_004842.2 620653 621369 D involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 620653..621369 Anaplasma marginale str. St. Maries 3171901 YP_153913.1 CDS AM681 NC_004842.2 621444 622055 D hypothetical protein identified by Glimmer 2; hypothetical protein 621444..622055 Anaplasma marginale str. St. Maries 3171528 YP_153914.1 CDS AM682 NC_004842.2 622067 622273 D hypothetical protein identified by Glimmer 2; hypothetical protein 622067..622273 Anaplasma marginale str. St. Maries 3171148 YP_153915.1 CDS AM683 NC_004842.2 622240 623646 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(622240..623646) Anaplasma marginale str. St. Maries 3170974 YP_153916.1 CDS ileS NC_004842.2 623938 627243 R IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin); isoleucyl-tRNA synthetase complement(623938..627243) Anaplasma marginale str. St. Maries 3171286 YP_153917.1 CDS AM685 NC_004842.2 627607 628089 D conserved hypothetical protein similar to NP_966995.1; hypothetical protein 627607..628089 Anaplasma marginale str. St. Maries 3171879 YP_153918.2 CDS AM686 NC_004842.2 628106 628837 D in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 628106..628837 Anaplasma marginale str. St. Maries 3171069 YP_153919.1 CDS AM688 NC_004842.2 628841 629110 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(628841..629110) Anaplasma marginale str. St. Maries 3171708 YP_153920.1 CDS AM689 NC_004842.2 629256 632300 D hypothetical protein identified by Glimmer 2; hypothetical protein 629256..632300 Anaplasma marginale str. St. Maries 3171033 YP_153921.1 CDS prfB NC_004842.2 632725 633741 R COG1186 PrfB protein chain release factor B; similar to NP_420681.1; peptide chain release factor 2 complement(632725..633741) Anaplasma marginale str. St. Maries 3171830 YP_153922.1 CDS AM694 NC_004842.2 634031 634783 R conserved hypothetical protein similar to NP_966267.1; hypothetical protein complement(634031..634783) Anaplasma marginale str. St. Maries 3171272 YP_153923.1 CDS gatA NC_004842.2 635162 636631 R allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A complement(635162..636631) Anaplasma marginale str. St. Maries 3171356 YP_153924.1 CDS folC NC_004842.2 636928 638220 D COG0285 FolC folylpolyglutamate synthase; similar to NP_360416.1; folylpolyglutamate synthase 636928..638220 Anaplasma marginale str. St. Maries 3171858 YP_153925.1 CDS hemC NC_004842.2 638378 639289 D transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 638378..639289 Anaplasma marginale str. St. Maries 3171518 YP_153926.1 CDS murB NC_004842.2 639264 640163 D catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 639264..640163 Anaplasma marginale str. St. Maries 3171591 YP_153927.1 CDS ankA NC_004842.2 640456 644619 D COG0666 Arp ankyrin repeat proteins; similar to AAP34825.1; ankyrin 640456..644619 Anaplasma marginale str. St. Maries 3171652 YP_153928.1 CDS nuoI NC_004842.2 645424 645906 R Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I complement(645424..645906) Anaplasma marginale str. St. Maries 3171289 YP_153929.1 CDS lepB NC_004842.2 645922 646641 R COG0681 LepB signal peptidase I; similar to AAD02938.1; signal peptidase complement(645922..646641) Anaplasma marginale str. St. Maries 3171521 YP_153930.1 CDS AM709 NC_004842.2 646652 647092 R conserved hypothetical protein similar to ZP_00210598.1; hypothetical protein complement(646652..647092) Anaplasma marginale str. St. Maries 3171847 YP_153931.1 CDS AM712 NC_004842.2 647660 658138 D hypothetical protein identified by Glimmer 2; hypothetical protein 647660..658138 Anaplasma marginale str. St. Maries 3171546 YP_153932.1 CDS AM715 NC_004842.2 658530 658817 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(658530..658817) Anaplasma marginale str. St. Maries 3171190 YP_153933.1 CDS orfX NC_004842.2 659399 659770 R other copies include: AM030, AM044, AM065, AM077 AM082, AM210, AM723, AM989, AM1061, AM1149 and AM1253; member of msp2 superfamily; hypothetical protein complement(659399..659770) Anaplasma marginale str. St. Maries 3171925 YP_153934.1 CDS orfY NC_004842.2 662843 663076 D other copies include: AM032, AM046, AM063, AM990 AM1059 and AM1251; member of msp2 superfamily; hypothetical protein 662843..663076 Anaplasma marginale str. St. Maries 3171664 YP_153935.1 CDS orfX NC_004842.2 663149 663547 D other copies include: AM030, AM044, AM065, AM077 AM082, AM210, AM717, AM989, AM1061, AM1149 and AM1253; member of msp2 superfamily; hypothetical protein 663149..663547 Anaplasma marginale str. St. Maries 3171909 YP_153936.1 CDS typA NC_004842.2 664842 666701 R COG1217 TypA predicted membrane GTPase involved in stress response; similar to NP_359986.1; GTP-binding protein complement(664842..666701) Anaplasma marginale str. St. Maries 3171339 YP_153937.1 CDS clpA NC_004842.2 666756 669101 R COG0542 ClpA ATPases with chaperone activity ATP-binding subunit; ATP-dependent Clp protease ATP-binding subunit complement(666756..669101) Anaplasma marginale str. St. Maries 3171912 YP_153938.1 CDS terC NC_004842.2 669205 669918 D COG0861 membrane protein TerC, possibly involved in tellurium resistance; membrane protein 669205..669918 Anaplasma marginale str. St. Maries 3171111 YP_153939.1 CDS rbfA NC_004842.2 670127 670480 R COG0858 RbfA ribosome-binding factor A; ribosome-binding factor A complement(670127..670480) Anaplasma marginale str. St. Maries 3171430 YP_153940.1 CDS infB NC_004842.2 670477 672975 R Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 complement(670477..672975) Anaplasma marginale str. St. Maries 3171936 YP_153941.1 CDS nusA NC_004842.2 672991 674538 R modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA complement(672991..674538) Anaplasma marginale str. St. Maries 3171460 YP_153942.1 CDS acrD NC_004842.2 675050 678163 R COG0841 AcrB cation/multidrug efflux pump; similar to NP_220560.1; acriflavin resistance protein D complement(675050..678163) Anaplasma marginale str. St. Maries 3171777 YP_153943.1 CDS tatC NC_004842.2 678393 679175 R COG0805 TatC Sec-independent protein secretion pathway component TatC; Sec-independent protein translocase protein complement(678393..679175) Anaplasma marginale str. St. Maries 3171090 YP_153944.1 CDS ispG NC_004842.2 679273 680541 R catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase complement(679273..680541) Anaplasma marginale str. St. Maries 3171787 YP_153945.1 CDS AM742 NC_004842.2 680569 681945 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(680569..681945) Anaplasma marginale str. St. Maries 3171270 YP_153946.1 CDS dxr NC_004842.2 682043 683233 R catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase complement(682043..683233) Anaplasma marginale str. St. Maries 3170951 YP_153947.1 CDS nuoN1 NC_004842.2 683247 684692 R COG1007 NuoN NADH:ubiquinone oxidoreductase subunit 2 (chain N); similar to NP_540062.1; NADH dehydrogenase subunit N complement(683247..684692) Anaplasma marginale str. St. Maries 3171778 YP_153948.1 CDS nuoM NC_004842.2 684695 686158 R COG1008 NuoM NADH:ubiquinone oxidoreductase subunit 4 (chain M); similar to NP_540063.1; NADH dehydrogenase subunit M complement(684695..686158) Anaplasma marginale str. St. Maries 3171383 YP_153949.1 CDS nuoL NC_004842.2 686155 688056 R COG1009 NuoL NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA; similar to NP_697827.1; NADH dehydrogenase subunit L complement(686155..688056) Anaplasma marginale str. St. Maries 3171031 YP_153950.1 CDS nuoK NC_004842.2 688124 688450 R COG0713 NuoK NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K); similar to NP_221141.1; NADH dehydrogenase subunit K complement(688124..688450) Anaplasma marginale str. St. Maries 3171555 YP_153951.1 CDS nuoJ NC_004842.2 688499 689101 R COG0839 NuoJ NADH:ubiquinone oxidoreductase subunit 6 (chain J); similar to NP_771548.1; NADH dehydrogenase subunit J complement(688499..689101) Anaplasma marginale str. St. Maries 3171559 YP_153952.1 CDS nuoF NC_004842.2 689290 690582 R part of NADH-ubiquinone oxidoreductase complex I; shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F complement(689290..690582) Anaplasma marginale str. St. Maries 3171696 YP_153953.1 CDS fadB NC_004842.2 690661 691824 R COG1250 FadB 3-hydroxyacyl-CoA dehydrogenase; similar to NP_220931.1; 3-hydroxyacyl-COA dehydrogenase complement(690661..691824) Anaplasma marginale str. St. Maries 3171285 YP_153954.1 CDS AM753 NC_004842.2 691830 692270 R conserved hypothetical protein similar to ZP_00210777.1; hypothetical protein complement(691830..692270) Anaplasma marginale str. St. Maries 3171063 YP_153955.1 CDS miaA NC_004842.2 692470 693387 D COG0324 MiaA tRNA delta(2)-isopentenylpyrophosphate transferase; tRNA isopentenylpyrophosphate transferase 692470..693387 Anaplasma marginale str. St. Maries 3171877 YP_153956.1 CDS AM757 NC_004842.2 693433 694188 R conserved family - type IV secretory pathway, component VirB8; hypothetical protein complement(693433..694188) Anaplasma marginale str. St. Maries 3171623 YP_153957.1 CDS AM758 NC_004842.2 694352 695701 R conserved family - RmuC recombination protein; hypothetical protein complement(694352..695701) Anaplasma marginale str. St. Maries 3171155 YP_153958.2 CDS serS NC_004842.2 695774 697063 D catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 695774..697063 Anaplasma marginale str. St. Maries 3171045 YP_153959.1 CDS AM760 NC_004842.2 697239 697784 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(697239..697784) Anaplasma marginale str. St. Maries 3171355 YP_153960.1 CDS hemF NC_004842.2 698064 698942 R catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase complement(698064..698942) Anaplasma marginale str. St. Maries 3171466 YP_153961.1 CDS agk NC_004842.2 699113 700093 R catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase complement(699113..700093) Anaplasma marginale str. St. Maries 3171723 YP_153962.1 CDS engB NC_004842.2 700038 700655 R binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC complement(700038..700655) Anaplasma marginale str. St. Maries 3171781 YP_153963.1 CDS prfA NC_004842.2 700982 702061 D recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 700982..702061 Anaplasma marginale str. St. Maries 3170972 YP_153964.1 CDS pccB NC_004842.2 702299 703846 R similar to NP_220986.1; propionyl-COA carboxylase subunit beta precursor complement(702299..703846) Anaplasma marginale str. St. Maries 3171605 YP_153965.1 CDS fpg NC_004842.2 704127 704936 R COG0266 Nei formamidopyrimidine-DNA glycosylase; formamidopyrimidine-DNA glycosylase complement(704127..704936) Anaplasma marginale str. St. Maries 3171637 YP_153966.1 CDS AM773 NC_004842.2 705141 706598 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(705141..706598) Anaplasma marginale str. St. Maries 3170941 YP_153967.1 CDS gltX NC_004842.2 706535 708085 D Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 706535..708085 Anaplasma marginale str. St. Maries 3171550 YP_153968.1 CDS AM776 NC_004842.2 708090 708344 D hypothetical protein identified by Glimmer 2; hypothetical protein 708090..708344 Anaplasma marginale str. St. Maries 3171474 YP_153969.1 CDS AM778 NC_004842.2 708764 710359 R conserved hypothetical protein similar to NP_966502.1; hypothetical protein complement(708764..710359) Anaplasma marginale str. St. Maries 3171048 YP_153970.1 CDS AM779 NC_004842.2 710794 712386 R conserved hypothetical protein similar to ZP_00210829.1; hypothetical protein complement(710794..712386) Anaplasma marginale str. St. Maries 3171792 YP_153971.1 CDS AM780 NC_004842.2 712414 714093 R conserved hypothetical protein similar to NP_966502.1; hypothetical protein complement(712414..714093) Anaplasma marginale str. St. Maries 3171341 YP_153972.1 CDS petC NC_004842.2 714379 715140 R COG2857 CYT1 cytochrome C1; similar to EAA25591.1; cytochrome C1, heme protein precursor complement(714379..715140) Anaplasma marginale str. St. Maries 3171845 YP_153973.1 CDS petB NC_004842.2 715141 716361 R COG3658 - cytochrome b; cytochrome B complement(715141..716361) Anaplasma marginale str. St. Maries 3171667 YP_153974.1 CDS petA NC_004842.2 716373 716897 R COG0723 QcrA Rieske Fe-S protein; similar to EAA25593.1; cytochrome B6-F complex iron-sulfur subunit complement(716373..716897) Anaplasma marginale str. St. Maries 3171452 YP_153975.1 CDS AM788 NC_004842.2 717206 717982 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(717206..717982) Anaplasma marginale str. St. Maries 3171278 YP_153976.1 CDS znuB NC_004842.2 718246 719049 R COG1108 ZnuB ABC-type Mn2+/Zn2+ transport systems, permease components; similar to NP_700279.1; zinc ABC transporter permease complement(718246..719049) Anaplasma marginale str. St. Maries 3171282 YP_153977.1 CDS AM790 NC_004842.2 719055 719408 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(719055..719408) Anaplasma marginale str. St. Maries 3171369 YP_153978.1 CDS tsf NC_004842.2 719430 720305 R EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts complement(719430..720305) Anaplasma marginale str. St. Maries 3171044 YP_153979.2 CDS rpsB NC_004842.2 720341 721324 R one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 complement(720341..721324) Anaplasma marginale str. St. Maries 3171326 YP_153980.1 CDS maf NC_004842.2 721473 722063 R Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein complement(721473..722063) Anaplasma marginale str. St. Maries 3171153 YP_153981.1 CDS infA NC_004842.2 722057 722392 R COG0424 Maf nucleotide-binding protein implicated in inhibition of septum formation; similar to NP_683835.1; translation initiation factor IF-1 complement(722057..722392) Anaplasma marginale str. St. Maries 3171532 YP_153982.1 CDS AM796 NC_004842.2 722389 723504 R conserved hypothetical protein similar to ZP_00210840.1; hypothetical protein complement(722389..723504) Anaplasma marginale str. St. Maries 3170992 YP_153983.1 CDS lpdA NC_004842.2 723470 724885 R COG1249 Lpd dihydrolipoamide dehydrogenase/glutathione oxidoreductase and related; dihydrolipoamide dehydrogenase complement(723470..724885) Anaplasma marginale str. St. Maries 3171324 YP_153984.1 CDS AM798 NC_004842.2 724893 726062 R conserved hypothetical protein similar to ZP_00210842.1; hypothetical protein complement(724893..726062) Anaplasma marginale str. St. Maries 3171378 YP_153985.1 CDS engA NC_004842.2 726383 727699 D EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 726383..727699 Anaplasma marginale str. St. Maries 3171493 YP_153986.1 CDS yibO NC_004842.2 727807 729384 R catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase complement(727807..729384) Anaplasma marginale str. St. Maries 3170957 YP_153987.2 CDS carA NC_004842.2 729593 730693 D catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 729593..730693 Anaplasma marginale str. St. Maries 3171503 YP_153988.1 CDS ispH NC_004842.2 730871 731899 D catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 730871..731899 Anaplasma marginale str. St. Maries 3171942 YP_153989.1 CDS dut NC_004842.2 732101 732544 D COG0756 Dut dUTPase; deoxyuridine 5'triphosphate nucleotidohydrolase 732101..732544 Anaplasma marginale str. St. Maries 3171654 YP_153990.1 CDS murF NC_004842.2 732591 733982 R COG0770 MurF UDP-N-acetylmuramyl pentapeptide synthase; UDP-N-acetylmuramyl-tripeptide synthetase complement(732591..733982) Anaplasma marginale str. St. Maries 3171850 YP_153991.1 CDS AM809 NC_004842.2 734205 734822 D conserved hypothetical protein similar to ZP_00210848.1; hypothetical protein 734205..734822 Anaplasma marginale str. St. Maries 3171908 YP_153992.1 CDS AM810 NC_004842.2 734837 739900 R conserved hypothetical protein similar to ZP_00142380.1; hypothetical protein complement(734837..739900) Anaplasma marginale str. St. Maries 3171059 YP_153993.1 CDS AM811 NC_004842.2 739863 743978 R conserved family - virB6 membrane component; hypothetical protein complement(739863..743978) Anaplasma marginale str. St. Maries 3171672 YP_153994.1 CDS AM812 NC_004842.2 743990 747049 R conserved family - virB6 membrane component; hypothetical protein complement(743990..747049) Anaplasma marginale str. St. Maries 3171336 YP_153995.1 CDS virB6 NC_004842.2 747102 749738 R COG3704 VirB6 type IV secretory pathway, VirB6 components; VirB6 protein complement(747102..749738) Anaplasma marginale str. St. Maries 3171332 YP_153996.1 CDS virB4 NC_004842.2 749731 752139 R COG3451 VirB4 type IV secretory pathway, VirB4 components; similar to AAM00407.1; other copies include: AM1053; type IV secretion system ATPase VirB4 complement(749731..752139) Anaplasma marginale str. St. Maries 3171241 YP_153997.1 CDS virB3 NC_004842.2 752143 752439 R COG3702 VirB3 type IV secretory pathway, VirB3 components; type IV secretion system protein VirB3 complement(752143..752439) Anaplasma marginale str. St. Maries 3171140 YP_153998.1 CDS sodB NC_004842.2 752533 753204 R COG0605 SodA superoxide dismutase; Fe superoxide dismutase complement(752533..753204) Anaplasma marginale str. St. Maries 3170979 YP_153999.1 CDS pstA NC_004842.2 753368 754753 D COG0581 PstA ABC-type phosphate transport system, permease component; similar to AAM00409.1; phosphate ABC transporter 753368..754753 Anaplasma marginale str. St. Maries 3171247 YP_154001.1 CDS lipA NC_004842.2 754976 755917 R catalyzes the radical-mediated insertion of two sulfur atoms into an ACP ACP bound to an octanoyl group to produce a lipoyl group; lipoyl synthase complement(754976..755917) Anaplasma marginale str. St. Maries 3171651 YP_154002.1 CDS AM821 NC_004842.2 756603 758225 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(756603..758225) Anaplasma marginale str. St. Maries 3171888 YP_154003.1 CDS AM823 NC_004842.2 758458 762411 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(758458..762411) Anaplasma marginale str. St. Maries 3171603 YP_154004.1 CDS pycA NC_004842.2 762503 764491 R COG1038 PycA pyruvate carboxylase, C-terminal domain/subunit; propionyl-CoA carboxylase subunit alpha complement(762503..764491) Anaplasma marginale str. St. Maries 3171022 YP_154005.1 CDS sfhB NC_004842.2 764861 765844 D COG0564 RluA pseudouridylate synthases, 23S RNA-specific; similar to EAA25988.1; sfhb-like protein 764861..765844 Anaplasma marginale str. St. Maries 3170969 YP_154006.1 CDS rpmB NC_004842.2 765847 766251 R required for 70S ribosome assembly; 50S ribosomal protein L28 complement(765847..766251) Anaplasma marginale str. St. Maries 3171017 YP_154007.1 CDS priA NC_004842.2 766755 768743 R COG1198 PriA primosomal protein N' (replication factor Y) - superfamily II helicase; similar to NP_360437.1; primosomal protein N' complement(766755..768743) Anaplasma marginale str. St. Maries 3171765 YP_154008.1 CDS AM829 NC_004842.2 768961 769884 R conserved hypothetical protein similar to NP_966301.1; hypothetical protein complement(768961..769884) Anaplasma marginale str. St. Maries 3171849 YP_154009.1 CDS AM830 NC_004842.2 770010 770813 R conserved family - uroporphyrinogen-III synthase; hypothetical protein complement(770010..770813) Anaplasma marginale str. St. Maries 3171353 YP_154010.1 CDS AM832 NC_004842.2 770910 772622 R conserved family - aminopeptidase P; hypothetical protein complement(770910..772622) Anaplasma marginale str. St. Maries 3171657 YP_154011.1 CDS AM833 NC_004842.2 772749 773276 R conserved hypothetical protein similar to NP_966046.1; hypothetical protein complement(772749..773276) Anaplasma marginale str. St. Maries 3171802 YP_154012.1 CDS AM836 NC_004842.2 773664 774524 R conserved hypothetical protein similar to NP_966501.1; hypothetical protein complement(773664..774524) Anaplasma marginale str. St. Maries 3171470 YP_154013.1 CDS era NC_004842.2 774500 775393 R Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era complement(774500..775393) Anaplasma marginale str. St. Maries 3171691 YP_154014.1 CDS ffh NC_004842.2 775488 776843 R COG0541 Ffh signal recognition particle GTPase; signal recognition particle protein complement(775488..776843) Anaplasma marginale str. St. Maries 3171372 YP_154015.1 CDS nuoL3 NC_004842.2 776836 778386 R subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; monovalent cation/H+ antiporter subunit D complement(776836..778386) Anaplasma marginale str. St. Maries 3171611 YP_154016.1 CDS AM841 NC_004842.2 778461 778937 R conserved family - oligoketide; hypothetical protein complement(778461..778937) Anaplasma marginale str. St. Maries 3171642 YP_154017.1 CDS dnaK NC_004842.2 779164 781101 R heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK complement(779164..781101) Anaplasma marginale str. St. Maries 3171733 YP_154018.1 CDS rne NC_004842.2 781301 783160 R COG1530 CafA ribonucleases G and E; similar to NP_220641.1; ribonuclease E complement(781301..783160) Anaplasma marginale str. St. Maries 3171675 YP_154019.1 CDS AM846 NC_004842.2 783255 783581 R subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit C complement(783255..783581) Anaplasma marginale str. St. Maries 3171495 YP_154020.1 CDS AM847 NC_004842.2 783668 784144 R subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit B complement(783668..784144) Anaplasma marginale str. St. Maries 3171328 YP_154021.1 CDS AM848 NC_004842.2 784101 784670 R subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit B complement(784101..784670) Anaplasma marginale str. St. Maries 3171208 YP_154022.1 CDS AM849 NC_004842.2 784671 784970 R subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit G complement(784671..784970) Anaplasma marginale str. St. Maries 3171671 YP_154023.1 CDS AM851 NC_004842.2 784977 785231 R subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit F complement(784977..785231) Anaplasma marginale str. St. Maries 3171563 YP_154024.1 CDS tktA NC_004842.2 785249 787234 R COG0021 TktA transketolase; similar to NP_698711.1; transketolase complement(785249..787234) Anaplasma marginale str. St. Maries 3171520 YP_154025.1 CDS AM853 NC_004842.2 787250 788854 R conserved family - carboxypeptidase; hypothetical protein complement(787250..788854) Anaplasma marginale str. St. Maries 3171279 YP_154026.1 CDS AM854 NC_004842.2 789000 789710 D conserved family - peptidoglycan-associated lipoprotein; hypothetical protein 789000..789710 Anaplasma marginale str. St. Maries 3171103 YP_154027.1 CDS purA NC_004842.2 790004 791341 D catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 790004..791341 Anaplasma marginale str. St. Maries 3171522 YP_154028.1 CDS AM858 NC_004842.2 791345 792331 R conserved family - GTP-binding protein; hypothetical protein complement(791345..792331) Anaplasma marginale str. St. Maries 3171344 YP_154029.1 CDS AM859 NC_004842.2 792369 792863 R conserved hypothetical protein similar to NP_965963.1; hypothetical protein complement(792369..792863) Anaplasma marginale str. St. Maries 3171234 YP_154030.1 CDS nrdA NC_004842.2 792908 794728 R Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha complement(792908..794728) Anaplasma marginale str. St. Maries 3171019 YP_154031.1 CDS ispA NC_004842.2 795296 796171 D COG0142 IspA geranylgeranyl pyrophosphate synthase; similar to NP_104814.1; geranyltranstransferase (farnesyl-diphosphate synthase) 795296..796171 Anaplasma marginale str. St. Maries 3171692 YP_154032.1 CDS AM862 NC_004842.2 796220 797116 D conserved hypothetical protein similar to NP_966903.1; hypothetical protein 796220..797116 Anaplasma marginale str. St. Maries 3171564 YP_154033.1 CDS thiO NC_004842.2 797146 798135 R similar to NP_819373.1; thiamine biosynthesis oxidoreductase complement(797146..798135) Anaplasma marginale str. St. Maries 3171812 YP_154034.1 CDS dnaB NC_004842.2 798415 799890 R unwinds double stranded DNA; replicative DNA helicase complement(798415..799890) Anaplasma marginale str. St. Maries 3171673 YP_154035.1 CDS AM867 NC_004842.2 799944 800618 R conserved hypothetical protein similar to ZP_00210892.1; hypothetical protein complement(799944..800618) Anaplasma marginale str. St. Maries 3171670 YP_154036.1 CDS ssnA NC_004842.2 800782 801246 D COG0402 SsnA cytosine deaminase and related metal-dependent hydrolases; similar to NP_542018.1; cytosine deaminase 800782..801246 Anaplasma marginale str. St. Maries 3171599 YP_154037.1 CDS fabH NC_004842.2 801378 802346 R COG0332 FabH 3-oxoacyl-[ACP synthase III; similar to NP_420182.1; 3-oxoacyl-ACP synthase complement(801378..802346) Anaplasma marginale str. St. Maries 3171592 YP_154038.1 CDS plsX NC_004842.2 802346 803389 R involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX complement(802346..803389) Anaplasma marginale str. St. Maries 3171506 YP_154039.1 CDS rpmF NC_004842.2 803389 803565 R some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 complement(803389..803565) Anaplasma marginale str. St. Maries 3170942 YP_154040.1 CDS tgt NC_004842.2 803779 805041 D COG0343 Tgt queuine/archaeosine tRNA-ribosyltransferase; queuine tRNA-ribosyltransferase 803779..805041 Anaplasma marginale str. St. Maries 3171674 YP_154041.1 CDS pstB NC_004842.2 805237 806061 R ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate ABC transporter ATP-binding protein complement(805237..806061) Anaplasma marginale str. St. Maries 3170944 YP_154042.1 CDS dapB NC_004842.2 806001 806843 R catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase complement(806001..806843) Anaplasma marginale str. St. Maries 3171085 YP_154043.1 CDS AM875 NC_004842.2 806956 807441 R conserved hypothetical protein similar to ZP_00142335.1; hypothetical protein complement(806956..807441) Anaplasma marginale str. St. Maries 3171021 YP_154044.1 CDS ubiA NC_004842.2 807454 808353 R UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; 4-hydroxybenzoate polyprenyltransferase complement(807454..808353) Anaplasma marginale str. St. Maries 3171489 YP_154045.1 CDS aaaP NC_004842.2 808427 809686 R experimental evidence exists for the production and secretion of this gene product; appendage-associated protein complement(808427..809686) Anaplasma marginale str. St. Maries 3170946 YP_154046.1 CDS AM879 NC_004842.2 809841 811124 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(809841..811124) Anaplasma marginale str. St. Maries 3171053 YP_154047.1 CDS AM880 NC_004842.2 811267 812109 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(811267..812109) Anaplasma marginale str. St. Maries 3171627 YP_154048.1 CDS rpmH NC_004842.2 812267 812401 D in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 812267..812401 Anaplasma marginale str. St. Maries 3171760 YP_154049.1 CDS AM881 NC_004842.2 812407 812766 D conserved hypothetical protein similar to ZP_00210903.1; hypothetical protein 812407..812766 Anaplasma marginale str. St. Maries 3171432 YP_154050.1 CDS AM882 NC_004842.2 812779 814098 D conserved family - Na+/alanine symporter; hypothetical protein 812779..814098 Anaplasma marginale str. St. Maries 3171863 YP_154051.1 CDS AM884 NC_004842.2 814157 816403 R conserved hypothetical protein similar to ZP_00210905.1; hypothetical protein complement(814157..816403) Anaplasma marginale str. St. Maries 3171187 YP_154052.1 CDS pheT NC_004842.2 816685 819048 R catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta complement(816685..819048) Anaplasma marginale str. St. Maries 3171554 YP_154053.1 CDS rplQ NC_004842.2 819052 819456 R is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 complement(819052..819456) Anaplasma marginale str. St. Maries 3170958 YP_154054.1 CDS rpoA NC_004842.2 819497 820597 R catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the subunit alpha is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha complement(819497..820597) Anaplasma marginale str. St. Maries 3171181 YP_154055.2 CDS rpsK NC_004842.2 820618 820992 R located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 complement(820618..820992) Anaplasma marginale str. St. Maries 3171713 YP_154056.1 CDS rpsM NC_004842.2 821002 821373 R located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 complement(821002..821373) Anaplasma marginale str. St. Maries 3171074 YP_154057.1 CDS adk NC_004842.2 821437 822087 R COG0563 Adk adenylate kinase and related kinases; adenylate kinase complement(821437..822087) Anaplasma marginale str. St. Maries 3171797 YP_154058.1 CDS secY NC_004842.2 822069 823370 R forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY complement(822069..823370) Anaplasma marginale str. St. Maries 3171260 YP_154059.1 CDS rplO NC_004842.2 823394 823834 R late assembly protein; 50S ribosomal protein L15 complement(823394..823834) Anaplasma marginale str. St. Maries 3171933 YP_154060.1 CDS rpsE NC_004842.2 823848 824372 R located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 complement(823848..824372) Anaplasma marginale str. St. Maries 3171365 YP_154061.1 CDS rplR NC_004842.2 824383 824760 R binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 complement(824383..824760) Anaplasma marginale str. St. Maries 3171012 YP_154062.1 CDS rplF NC_004842.2 824762 825307 R ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 complement(824762..825307) Anaplasma marginale str. St. Maries 3171058 YP_154063.1 CDS rpsH NC_004842.2 825319 825717 R binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 complement(825319..825717) Anaplasma marginale str. St. Maries 3171439 YP_154064.1 CDS rpsN NC_004842.2 825735 825983 R COG0199 RpsN ribosomal protein S14; small ribosomal protein S14 complement(825735..825983) Anaplasma marginale str. St. Maries 3170962 YP_154065.1 CDS rplE NC_004842.2 826052 826591 R part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 complement(826052..826591) Anaplasma marginale str. St. Maries 3171317 YP_154066.1 CDS rplX NC_004842.2 826592 826909 R assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 complement(826592..826909) Anaplasma marginale str. St. Maries 3171000 YP_154067.1 CDS rplN NC_004842.2 826906 827265 R binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 complement(826906..827265) Anaplasma marginale str. St. Maries 3171832 YP_154068.1 CDS rpsQ NC_004842.2 827278 827511 R primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 complement(827278..827511) Anaplasma marginale str. St. Maries 3171179 YP_154069.1 CDS rpmC NC_004842.2 827501 827707 R one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 complement(827501..827707) Anaplasma marginale str. St. Maries 3171018 YP_154070.2 CDS rplP NC_004842.2 827715 828131 R located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 complement(827715..828131) Anaplasma marginale str. St. Maries 3171770 YP_154071.1 CDS rpsC NC_004842.2 828140 828775 R forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 complement(828140..828775) Anaplasma marginale str. St. Maries 3171028 YP_154072.1 CDS rplV NC_004842.2 828779 829117 R binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 complement(828779..829117) Anaplasma marginale str. St. Maries 3171426 YP_154073.1 CDS rpsS NC_004842.2 829121 829402 R protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 complement(829121..829402) Anaplasma marginale str. St. Maries 3171726 YP_154074.1 CDS rplB NC_004842.2 829408 830241 R one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 complement(829408..830241) Anaplasma marginale str. St. Maries 3171922 YP_154075.1 CDS rplW NC_004842.2 830238 830546 R binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 complement(830238..830546) Anaplasma marginale str. St. Maries 3171227 YP_154076.1 CDS rplD NC_004842.2 830521 831147 R L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 complement(830521..831147) Anaplasma marginale str. St. Maries 3171811 YP_154077.1 CDS rplC NC_004842.2 831165 831863 R binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 complement(831165..831863) Anaplasma marginale str. St. Maries 3171188 YP_154078.1 CDS rpsJ NC_004842.2 831865 832182 R NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 complement(831865..832182) Anaplasma marginale str. St. Maries 3171590 YP_154079.1 CDS tuf NC_004842.2 832189 833370 R EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu complement(832189..833370) Anaplasma marginale str. St. Maries 3171810 YP_154080.1 CDS AM915 NC_004842.2 833746 834531 D conserved family - tRNA/rRNA methyltransferase; hypothetical protein 833746..834531 Anaplasma marginale str. St. Maries 3171530 YP_154081.1 CDS cmk NC_004842.2 834518 835195 D COG0283 Cmk cytidylate kinase; cytidylate kinase 834518..835195 Anaplasma marginale str. St. Maries 3171027 YP_154082.1 CDS rpsA NC_004842.2 835260 836939 D in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 835260..836939 Anaplasma marginale str. St. Maries 3171487 YP_154083.1 CDS sppA NC_004842.2 836943 837824 D COG0616 SppA periplasmic serine proteases (ClpP class); similar to NP_104359.1; protease IV 836943..837824 Anaplasma marginale str. St. Maries 3171569 YP_154084.1 CDS AM919 NC_004842.2 838073 838570 D hypothetical protein identified by Glimmer 2; hypothetical protein 838073..838570 Anaplasma marginale str. St. Maries 3171024 YP_154085.1 CDS AM920 NC_004842.2 838571 839008 D hypothetical protein identified by Glimmer 2; hypothetical protein 838571..839008 Anaplasma marginale str. St. Maries 3171676 YP_154086.1 CDS AM921 NC_004842.2 839324 840277 D hypothetical protein identified by Glimmer 2; hypothetical protein 839324..840277 Anaplasma marginale str. St. Maries 3171154 YP_154087.1 CDS hemH NC_004842.2 840581 841633 D protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 840581..841633 Anaplasma marginale str. St. Maries 3171414 YP_154088.1 CDS AM923 NC_004842.2 841636 842700 R conserved family - ATPase; hypothetical protein complement(841636..842700) Anaplasma marginale str. St. Maries 3171661 YP_154089.1 CDS AM924 NC_004842.2 842956 843282 R conserved hypothetical protein similar to ZP_00210943.1; hypothetical protein complement(842956..843282) Anaplasma marginale str. St. Maries 3171531 YP_154090.1 CDS hflK NC_004842.2 843819 844742 R COG0330 HflC membrane protease subunits stomatin/prohibitin homologs; similar to NP_815489.1; second copy is ORF AM1064; HFLK protein complement(843819..844742) Anaplasma marginale str. St. Maries 3171167 YP_154091.1 CDS AM926 NC_004842.2 844805 845653 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(844805..845653) Anaplasma marginale str. St. Maries 3171921 YP_154092.1 CDS AM927 NC_004842.2 845751 848354 D conserved family - ATP-dependent nuclease; hypothetical protein 845751..848354 Anaplasma marginale str. St. Maries 3171747 YP_154093.1 CDS qor NC_004842.2 848679 849662 R COG0604 Qor NADPH:quinone reductase and related Zn-dependent oxidoreductases; similar to NP_102293.1; quinone oxidoreductase complement(848679..849662) Anaplasma marginale str. St. Maries 3171311 YP_154094.1 CDS AM929 NC_004842.2 849768 852170 R conserved family - alkaline protease secretion ATP-binding protein; hypothetical protein complement(849768..852170) Anaplasma marginale str. St. Maries 3171467 YP_154095.1 CDS folP NC_004842.2 852504 853310 D COG0294 FolP dihydropteroate synthase and related enzymes; similar to NP_279484.1; dihydropteroate synthase 852504..853310 Anaplasma marginale str. St. Maries 3171211 YP_154096.1 CDS carB NC_004842.2 853769 857077 D four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 853769..857077 Anaplasma marginale str. St. Maries 3171824 YP_154097.1 CDS AM936 NC_004842.2 858293 858685 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(858293..858685) Anaplasma marginale str. St. Maries 3171084 YP_154098.1 CDS fumC NC_004842.2 858850 860238 R class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase complement(858850..860238) Anaplasma marginale str. St. Maries 3171020 YP_154099.1 CDS AM938 NC_004842.2 860408 861058 D conserved family - pantothenate metabolism flavoprotein; hypothetical protein 860408..861058 Anaplasma marginale str. St. Maries 3171473 YP_154100.1 CDS pyrC NC_004842.2 861059 862423 D dihydroorotase and related cyclic amidohydrolases; similar to ZP_00210957.1; dihydroorotase 861059..862423 Anaplasma marginale str. St. Maries 3171338 YP_154101.1 CDS glmM NC_004842.2 862557 863915 R COG1109 CpsG phosphomannomutase; similar to NP_698675.1; phosphoglucosamine mutase complement(862557..863915) Anaplasma marginale str. St. Maries 3171422 YP_154102.1 CDS lipB NC_004842.2 863952 864596 R lipoyl-[acyl-carrier protein]-protein-N-lipoyltransferse; lipoate-protein ligase B; transfers lipoate to apolipoproteins; involved in lipoate metabolism; lipoyltransferase complement(863952..864596) Anaplasma marginale str. St. Maries 3170953 YP_154103.1 CDS radC NC_004842.2 864687 865379 R COG2003 RadC DNA repair proteins; DNA repair protein complement(864687..865379) Anaplasma marginale str. St. Maries 3171106 YP_154104.2 CDS groES NC_004842.2 865600 865884 D 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 865600..865884 Anaplasma marginale str. St. Maries 3171906 YP_154105.1 CDS groEL NC_004842.2 865932 867581 D 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 865932..867581 Anaplasma marginale str. St. Maries 3171347 YP_154106.1 CDS AM947 NC_004842.2 868196 868927 R conserved family - oxidoreductase short-chain dehydrogenase; hypothetical protein complement(868196..868927) Anaplasma marginale str. St. Maries 3171406 YP_154107.1 CDS clpB NC_004842.2 869149 871767 D COG0542 ATPases with chaperone activity ATP-binding subunit; ATP-dependent Clp protease ATP-binding subunit 869149..871767 Anaplasma marginale str. St. Maries 3171491 YP_154108.1 CDS AM950 NC_004842.2 871879 873540 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(871879..873540) Anaplasma marginale str. St. Maries 3171589 YP_154109.1 CDS AM952 NC_004842.2 873771 874763 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(873771..874763) Anaplasma marginale str. St. Maries 3171070 YP_154110.1 CDS AM953 NC_004842.2 874868 875608 R conserved family - dioxygenase; hypothetical protein complement(874868..875608) Anaplasma marginale str. St. Maries 3171927 YP_154111.1 CDS AM955 NC_004842.2 875813 876211 D hypothetical protein identified by Glimmer 2; hypothetical protein 875813..876211 Anaplasma marginale str. St. Maries 3170985 YP_154112.1 CDS pepA NC_004842.2 876183 877787 D catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 876183..877787 Anaplasma marginale str. St. Maries 3171893 YP_154113.1 CDS AM957 NC_004842.2 877803 878447 D conserved family - phosphoribosylglycinamide formyltransferase; hypothetical protein 877803..878447 Anaplasma marginale str. St. Maries 3170991 YP_154114.1 CDS AM959 NC_004842.2 878594 880069 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(878594..880069) Anaplasma marginale str. St. Maries 3170954 YP_154115.1 CDS purQ NC_004842.2 880211 880993 R COG0046 PurL phosphoribosylformylglycinamidine (synthase, synthetase domain; similar to NP_868461.1; phosphoribosylformylglycinamidine synthase complement(880211..880993) Anaplasma marginale str. St. Maries 3171298 YP_154116.1 CDS gidA NC_004842.2 881074 882987 D GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 881074..882987 Anaplasma marginale str. St. Maries 3171193 YP_154117.1 CDS glpX NC_004842.2 883300 884265 R type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II complement(883300..884265) Anaplasma marginale str. St. Maries 3171566 YP_154118.1 CDS AM965 NC_004842.2 884352 885053 D conserved hypothetical protein similar to NP_252313.1; hypothetical protein 884352..885053 Anaplasma marginale str. St. Maries 3171060 YP_154119.1 CDS AM967 NC_004842.2 885213 885668 D conserved hypothetical protein similar to ZP_00210971.1; hypothetical protein 885213..885668 Anaplasma marginale str. St. Maries 3171515 YP_154120.1 CDS AM968 NC_004842.2 885769 886053 D hypothetical protein identified by Glimmer 2; hypothetical protein 885769..886053 Anaplasma marginale str. St. Maries 3171613 YP_154121.1 CDS bioB NC_004842.2 886040 887014 D COG0502 BioB biotin synthase and related enzymes; similar to NP_415296.1; biotin synthase 886040..887014 Anaplasma marginale str. St. Maries 3171351 YP_154122.1 CDS purL NC_004842.2 887742 890792 D COG0046 PurL phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; phosphoribosylformylglycinamidine synthase 887742..890792 Anaplasma marginale str. St. Maries 3171381 YP_154123.1 CDS AM974 NC_004842.2 890823 891029 D hypothetical protein identified by Glimmer 2; hypothetical protein 890823..891029 Anaplasma marginale str. St. Maries 3171887 YP_154124.1 CDS AM975 NC_004842.2 891166 891870 D conserved family - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase; hypothetical protein 891166..891870 Anaplasma marginale str. St. Maries 3171457 YP_154125.1 CDS AM976 NC_004842.2 891926 892141 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(891926..892141) Anaplasma marginale str. St. Maries 3171221 YP_154126.1 CDS AM977 NC_004842.2 892150 892698 R conserved hypothetical protein similar to ZP_00210976.1; hypothetical protein complement(892150..892698) Anaplasma marginale str. St. Maries 3171441 YP_154127.1 CDS AM979 NC_004842.2 892797 894077 R conserved hypothetical protein similar to NP_420685.1; hypothetical protein complement(892797..894077) Anaplasma marginale str. St. Maries 3171903 YP_154128.1 CDS AM980 NC_004842.2 894252 894620 D conserved family - uncharacterized homolog of plant Iojap protein; hypothetical protein 894252..894620 Anaplasma marginale str. St. Maries 3171046 YP_154129.1 CDS AM981 NC_004842.2 894865 895755 D conserved hypothetical protein similar to NP_965909.1; hypothetical protein 894865..895755 Anaplasma marginale str. St. Maries 3171609 YP_154130.1 CDS AM982 NC_004842.2 895993 896646 R conserved hypothetical protein similar to NP_966750.1; hypothetical protein complement(895993..896646) Anaplasma marginale str. St. Maries 3171826 YP_154131.1 CDS purM NC_004842.2 896760 897815 D catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 896760..897815 Anaplasma marginale str. St. Maries 3171880 YP_154132.1 CDS xerC NC_004842.2 897807 898757 R COG0582 XerC integrase; similar to NP_698893.1; integrase/recombinase ripx complement(897807..898757) Anaplasma marginale str. St. Maries 3171434 YP_154133.1 CDS gpsA NC_004842.2 898926 900095 D COG0240 GpsA glycerol 3-phosphate dehydrogenase; gylcerol-3-phosphate dehydrogenase 898926..900095 Anaplasma marginale str. St. Maries 3171794 YP_154134.1 CDS omp15 NC_004842.2 900092 900547 D member of msp2 superfamily; outer membrane protein 15 900092..900547 Anaplasma marginale str. St. Maries 3171905 YP_154135.1 CDS orfX NC_004842.2 900783 901157 R other copies include: AM030, AM044, AM065, AM077 AM082, AM210, AM717, AM723, AM1061, AM1149 and AM1253; member of msp2 superfamily; hypothetical protein complement(900783..901157) Anaplasma marginale str. St. Maries 3170982 YP_154136.1 CDS orfY NC_004842.2 901157 901468 R other copies include: AM032, AM046, AM063, AM721 AM1059 and AM1251; member of msp2 superfamily; hypothetical protein complement(901157..901468) Anaplasma marginale str. St. Maries 3171402 YP_154137.1 CDS rho NC_004842.2 901852 903234 R An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho complement(901852..903234) Anaplasma marginale str. St. Maries 3171483 YP_154138.1 CDS AM997 NC_004842.2 903504 903842 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(903504..903842) Anaplasma marginale str. St. Maries 3171065 YP_154139.1 CDS hslV NC_004842.2 904024 904593 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 904024..904593 Anaplasma marginale str. St. Maries 3171721 YP_154140.1 CDS hslU NC_004842.2 904590 906038 D heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 904590..906038 Anaplasma marginale str. St. Maries 3171389 YP_154141.1 CDS ubiE NC_004842.2 906042 906785 D COG2226 UbiE methylase involved in ubiquinone/menaquinone biosynthesis; similar to NP_700228.1; ubiquinone/menaquinone biosynthesis methyltransferase 906042..906785 Anaplasma marginale str. St. Maries 3171144 YP_154142.1 CDS metS NC_004842.2 906786 908153 R COG0143 MetG methionyl-tRNA synthetase; similar to NP_360683.1; methionyl-tRNA synthetase complement(906786..908153) Anaplasma marginale str. St. Maries 3171113 YP_154143.1 CDS lysC NC_004842.2 908599 909837 D catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 908599..909837 Anaplasma marginale str. St. Maries 3171456 YP_154144.1 CDS AM1006 NC_004842.2 909871 910086 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(909871..910086) Anaplasma marginale str. St. Maries 3171739 YP_154145.1 CDS coxB NC_004842.2 910094 910924 D COG1622 CyoA Heme/copper-type cytochrome/quinol oxidases, subunit 2; cytochrome C oxidase subunit II 910094..910924 Anaplasma marginale str. St. Maries 3171940 YP_154146.1 CDS coxA NC_004842.2 911021 912586 D COG0843 CyoB Heme/copper-type cytochrome/quinol oxidases, subunit 1; cytochrome C oxidase subunit I 911021..912586 Anaplasma marginale str. St. Maries 3171121 YP_154147.1 CDS ctaB NC_004842.2 912596 913501 D converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 912596..913501 Anaplasma marginale str. St. Maries 3171191 YP_154148.1 CDS AM1010 NC_004842.2 913554 914480 R conserved family - DNA uptake lipoprotein; hypothetical protein complement(913554..914480) Anaplasma marginale str. St. Maries 3171836 YP_154149.1 CDS purD NC_004842.2 914624 915886 D catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 914624..915886 Anaplasma marginale str. St. Maries 3171271 YP_154150.1 CDS yajC NC_004842.2 915917 916423 D COG1862 YajC preprotein translocase subunit YajC; preprotein translocase subunit 915917..916423 Anaplasma marginale str. St. Maries 3171479 YP_154151.1 CDS glmS NC_004842.2 916492 918318 D COG0449 GlmS glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar; similar to NP_771247.1; glucosamine--fructose-6-phosphate aminotransferase 916492..918318 Anaplasma marginale str. St. Maries 3170947 YP_154152.1 CDS dnaN NC_004842.2 918685 919824 R COG0592 DnaN DNA polymerase sliding clamp subunit (PCNA homolog); DNA polymerase III subunit beta complement(918685..919824) Anaplasma marginale str. St. Maries 3171846 YP_154153.1 CDS rnd NC_004842.2 920045 920659 R COG0349 Rnd ribonuclease D; other copies include: AM151; ribonuclease D complement(920045..920659) Anaplasma marginale str. St. Maries 3171891 YP_154154.1 CDS czcR NC_004842.2 920724 921596 R COG0745 OmpR response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding; transcriptional activator protein complement(920724..921596) Anaplasma marginale str. St. Maries 3171156 YP_154155.1 CDS AM1018 NC_004842.2 921897 922544 R conserved family - transcriptional regulator; hypothetical protein complement(921897..922544) Anaplasma marginale str. St. Maries 3171584 YP_154156.1 CDS ppa NC_004842.2 923388 923915 R COG0221 Ppa inorganic pyrophosphatase; inorganic phosphatase protein complement(923388..923915) Anaplasma marginale str. St. Maries 3171884 YP_154157.1 CDS AM1021 NC_004842.2 924979 925203 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(924979..925203) Anaplasma marginale str. St. Maries 3171178 YP_154158.1 CDS rpsI NC_004842.2 925139 925600 R forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 complement(925139..925600) Anaplasma marginale str. St. Maries 3170995 YP_154159.1 CDS rplM NC_004842.2 925572 926084 R in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 complement(925572..926084) Anaplasma marginale str. St. Maries 3171720 YP_154160.1 CDS tolC NC_004842.2 926120 927517 D COG1538 TolC outer membrane protein; outer membrane protein 926120..927517 Anaplasma marginale str. St. Maries 3171364 YP_154161.1 CDS AM1025 NC_004842.2 927536 928129 D conserved hypothetical protein similar to NP_965897.1; hypothetical protein 927536..928129 Anaplasma marginale str. St. Maries 3171568 YP_154162.1 CDS AM1027 NC_004842.2 928257 929288 R conserved family - ATPase involved in chromosome partitioning; hypothetical protein complement(928257..929288) Anaplasma marginale str. St. Maries 3171782 YP_154163.1 CDS prsA NC_004842.2 929392 930171 D COG0462 PrsA phosphoribosylpyrophosphate synthetase; similar to NP_797118.1; phosphoribosylpyrophosphate synthetase 929392..930171 Anaplasma marginale str. St. Maries 3171081 YP_154164.1 CDS AM1030 NC_004842.2 930364 930684 D hypothetical protein identified by Glimmer 2; hypothetical protein 930364..930684 Anaplasma marginale str. St. Maries 3171680 YP_154165.2 CDS acnA NC_004842.2 930720 933356 R Catalyzes the conversion of citrate to isocitrate; aconitate hydratase complement(930720..933356) Anaplasma marginale str. St. Maries 3171805 YP_154166.1 CDS apaG NC_004842.2 933744 934196 R protein associated with Co2+ and Mg2+ efflux; ApaG protein complement(933744..934196) Anaplasma marginale str. St. Maries 3171080 YP_154167.1 CDS purK NC_004842.2 934272 935342 D COG0026 PurK phosphoribosylaminoimidazole carboxylase (NCAIR synthetase); similar to NP_830163.1; phosphoribosylaminoimidazole carboxylase 934272..935342 Anaplasma marginale str. St. Maries 3171226 YP_154168.1 CDS AM1037 NC_004842.2 935472 937625 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(935472..937625) Anaplasma marginale str. St. Maries 3171224 YP_154169.1 CDS AM1041 NC_004842.2 938242 939717 D hypothetical protein identified by Glimmer 2; hypothetical protein 938242..939717 Anaplasma marginale str. St. Maries 3171274 YP_154170.1 CDS AM1046 NC_004842.2 940029 941474 D hypothetical protein identified by Glimmer 2; hypothetical protein 940029..941474 Anaplasma marginale str. St. Maries 3171418 YP_154171.1 CDS AM1048 NC_004842.2 941505 945434 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(941505..945434) Anaplasma marginale str. St. Maries 3171127 YP_154172.1 CDS AM1050 NC_004842.2 945638 949768 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(945638..949768) Anaplasma marginale str. St. Maries 3171904 YP_154173.1 CDS AM1051 NC_004842.2 950058 955655 R conserved hypothetical protein similar to ZP_00210463.1; hypothetical protein complement(950058..955655) Anaplasma marginale str. St. Maries 3171870 YP_154174.1 CDS virB4 NC_004842.2 956209 958638 R COG3451 VirB4 type IV secretory pathway, VirB4 components; other copies include: AM814; VirB4 protein complement(956209..958638) Anaplasma marginale str. St. Maries 3171206 YP_154175.1 CDS AM1054 NC_004842.2 958771 959145 R hypothetical protein identified by Glimmer 2; identity to Anaplasma (AAO41098.1) - but not the same as hypothetical protein; hypothetical protein complement(958771..959145) Anaplasma marginale str. St. Maries 3171202 YP_154176.1 CDS AM1055 NC_004842.2 959418 959795 R conserved hypothetical protein similar to NP_966415.1; identity to Anaplasma (AAO41098.1) but not the same as hypothetical protein; hypothetical protein complement(959418..959795) Anaplasma marginale str. St. Maries 3171604 YP_154177.1 CDS AM1056 NC_004842.2 960582 961172 R conserved hypothetical protein similar to ZP_00210466.1; identity to Anaplasma (AAO41095.1) but not the same as hypothetical protein; hypothetical protein complement(960582..961172) Anaplasma marginale str. St. Maries 3171165 YP_154178.1 CDS AM1057 NC_004842.2 961182 961730 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(961182..961730) Anaplasma marginale str. St. Maries 3171216 YP_154179.1 CDS AM1058 NC_004842.2 961959 962324 D hypothetical protein identified by Glimmer 2; hypothetical protein 961959..962324 Anaplasma marginale str. St. Maries 3171276 YP_154180.1 CDS orfY NC_004842.2 962297 962566 D other copies include: AM032, AM046, AM063, AM721 AM990 and AM1251; member of msp2 superfamily; hypothetical protein 962297..962566 Anaplasma marginale str. St. Maries 3171349 YP_154181.1 CDS orfX NC_004842.2 962633 963028 D other copies include: AM030, AM044, AM065, AM077 AM082, AM210, AM717, AM723, AM989, AM1149 and AM1253; member of msp2 superfamily; hypothetical protein 962633..963028 Anaplasma marginale str. St. Maries 3171038 YP_154182.1 CDS msp3 NC_004842.2 963365 966196 D similar to AAN05084.1; member of msp2 superfamily; msp3 expression site; major surface protein 3 963365..966196 Anaplasma marginale str. St. Maries 3171716 YP_154183.1 CDS hflK NC_004842.2 966443 967555 D COG0330 HflC membrane protease subunits stomatin/prohibitin homologs; similar to NP_220514.1; other copies include: AM925; hflK protein 966443..967555 Anaplasma marginale str. St. Maries 3171222 YP_154184.1 CDS hflC NC_004842.2 967557 968429 D COG0330 HflC membrane protease subunits stomatin/prohibitin homologs; similar to NP_220515.1; hflC protein 967557..968429 Anaplasma marginale str. St. Maries 3171871 YP_154185.1 CDS AM1066 NC_004842.2 968432 969895 D conserved family - serine protease; hypothetical protein 968432..969895 Anaplasma marginale str. St. Maries 3171075 YP_154186.1 CDS AM1067 NC_004842.2 969888 970502 D conserved hypothetical protein similar to ZP_00210471.1; hypothetical protein 969888..970502 Anaplasma marginale str. St. Maries 3171248 YP_154187.1 CDS rnc NC_004842.2 970489 971187 D cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 970489..971187 Anaplasma marginale str. St. Maries 3171624 YP_154188.1 CDS cox11 NC_004842.2 971218 971841 D involved in the insertion of copper into subunit I of cytochrome C oxidase; cytochrome C oxidase assembly protein 971218..971841 Anaplasma marginale str. St. Maries 3171525 YP_154189.1 CDS AM1073 NC_004842.2 971851 972633 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(971851..972633) Anaplasma marginale str. St. Maries 3171822 YP_154190.1 CDS ana29 NC_004842.2 972972 973766 R similar to AAP34273.1; hypothetical protein complement(972972..973766) Anaplasma marginale str. St. Maries 3171488 YP_154191.1 CDS AM1077 NC_004842.2 973899 974120 D hypothetical protein identified by Glimmer 2; hypothetical protein 973899..974120 Anaplasma marginale str. St. Maries 3171895 YP_154192.1 CDS AM1078 NC_004842.2 974177 975052 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(974177..975052) Anaplasma marginale str. St. Maries 3171277 YP_154193.1 CDS AM1079 NC_004842.2 975249 976583 R conserved family - protease; hypothetical protein complement(975249..976583) Anaplasma marginale str. St. Maries 3170960 YP_154194.1 CDS AM1080 NC_004842.2 976596 978017 R conserved family - protease; hypothetical protein complement(976596..978017) Anaplasma marginale str. St. Maries 3171294 YP_154195.1 CDS lspA NC_004842.2 977980 978492 R lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase complement(977980..978492) Anaplasma marginale str. St. Maries 3170986 YP_154196.1 CDS ribF NC_004842.2 978571 979482 R COG0196 RibF FAD synthase; riboflavin kinase / FAD synthetase protein complement(978571..979482) Anaplasma marginale str. St. Maries 3171451 YP_154197.1 CDS grxC1 NC_004842.2 979550 979792 D COG0695 GrxC glutaredoxin and related proteins; glutaredoxin 979550..979792 Anaplasma marginale str. St. Maries 3171644 YP_154198.1 CDS hemK NC_004842.2 979944 980801 R COG2890 HemK predicted rRNA or tRNA methylase; protein-(glutamine-N5) methyltransferase complement(979944..980801) Anaplasma marginale str. St. Maries 3171204 YP_154199.1 CDS map NC_004842.2 980982 981779 R catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase complement(980982..981779) Anaplasma marginale str. St. Maries 3171219 YP_154200.1 CDS sucB NC_004842.2 981783 983096 R COG0508 AceF dihydrolipoamide acyltransferases; dihydrolipoamide acetyltransferase component complement(981783..983096) Anaplasma marginale str. St. Maries 3171445 YP_154201.1 CDS AM1088 NC_004842.2 983127 983516 R conserved hypothetical protein similar to ZP_00053362.1; hypothetical protein complement(983127..983516) Anaplasma marginale str. St. Maries 3171472 YP_154202.1 CDS panC NC_004842.2 983746 984645 R COG0414 PanC pantothenate synthetase; pantoate--beta-alanine ligase complement(983746..984645) Anaplasma marginale str. St. Maries 3171235 YP_154203.1 CDS AM1091 NC_004842.2 984734 985876 D conserved family - D-alanyl-D-alanine carboxypeptidasecarboxylpeptidase; hypothetical protein 984734..985876 Anaplasma marginale str. St. Maries 3171937 YP_154204.1 CDS dsbD NC_004842.2 985863 987092 R COG0526 TrxA thiol-disulfide isomerase and thioredoxins; cytochrome C biogenesis protein complement(985863..987092) Anaplasma marginale str. St. Maries 3171412 YP_154205.1 CDS AM1093 NC_004842.2 987136 987468 R conserved hypothetical protein similar to NP_966808.1; hypothetical protein complement(987136..987468) Anaplasma marginale str. St. Maries 3171131 YP_154206.1 CDS AM1094 NC_004842.2 987506 988609 D conserved family - metallopeptidase; hypothetical protein 987506..988609 Anaplasma marginale str. St. Maries 3171553 YP_154207.1 CDS oma87 NC_004842.2 988615 990954 D COG4775 - outer membrane protein/protective antigen OMA87; similar to NP_359839.1; outer membrane protein 988615..990954 Anaplasma marginale str. St. Maries 3171367 YP_154208.1 CDS AM1097 NC_004842.2 990941 991501 D conserved family - outer membrane protein; hypothetical protein 990941..991501 Anaplasma marginale str. St. Maries 3171362 YP_154209.1 CDS fabZ NC_004842.2 991507 991950 D in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 991507..991950 Anaplasma marginale str. St. Maries 3171049 YP_154210.1 CDS purH NC_004842.2 991965 993506 D COG0138 PurH AICAR transformylase/IMP cyclohydrolase PurH; similar to NP_767221.1; phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase) 991965..993506 Anaplasma marginale str. St. Maries 3171920 YP_154211.1 CDS pgsA NC_004842.2 993515 994057 R COG0558 PgsA phosphatidylglycerophosphate synthase; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase complement(993515..994057) Anaplasma marginale str. St. Maries 3171136 YP_154212.1 CDS AM1103 NC_004842.2 994766 996070 D conserved hypothetical protein similar to NP_220763.1; hypothetical protein 994766..996070 Anaplasma marginale str. St. Maries 3171310 YP_154213.1 CDS slt NC_004842.2 996098 998122 D COG0741 MltE soluble lytic murein transglycosylase and related regulatory proteins (some); soluble lytic murein transglycosylase precursor 996098..998122 Anaplasma marginale str. St. Maries 3171815 YP_154214.1 CDS surf1 NC_004842.2 998129 998815 R COG3346 - uncharacterized conserved protein; similar to NP_360750.1; surfeit locus protein 1 complement(998129..998815) Anaplasma marginale str. St. Maries 3171913 YP_154215.1 CDS AM1108 NC_004842.2 999373 1001166 D conserved hypothetical protein similar to NP_220935.1; hypothetical protein 999373..1001166 Anaplasma marginale str. St. Maries 3171853 YP_154216.1 CDS AM1109 NC_004842.2 1001259 1002611 R conserved family - dehydrogenase; hypothetical protein complement(1001259..1002611) Anaplasma marginale str. St. Maries 3171171 YP_154217.1 CDS atpB NC_004842.2 1002680 1003483 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 1002680..1003483 Anaplasma marginale str. St. Maries 3171523 YP_154218.1 CDS AM1111 NC_004842.2 1003567 1004193 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(1003567..1004193) Anaplasma marginale str. St. Maries 3171462 YP_154219.2 CDS atpE NC_004842.2 1004848 1005072 D Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 1004848..1005072 Anaplasma marginale str. St. Maries 3171687 YP_154220.1 CDS AM1113 NC_004842.2 1005079 1005579 D conserved hypothetical protein similar to ZP_00210501.1; hypothetical protein 1005079..1005579 Anaplasma marginale str. St. Maries 3171855 YP_154221.1 CDS AM1114 NC_004842.2 1005576 1006073 D conserved hypothetical protein similar to ZP_00210502.1; hypothetical protein 1005576..1006073 Anaplasma marginale str. St. Maries 3171764 YP_154222.1 CDS ftsA NC_004842.2 1006198 1007472 R COG0849 FtsA predicted ATPases of the HSP70 class involved in cell division; cell division protein FtsA complement(1006198..1007472) Anaplasma marginale str. St. Maries 3171749 YP_154223.1 CDS trkH NC_004842.2 1007504 1009075 R COG0168 TrkG Trk-type K+ transport systems membrane components; similar to NP_791626.1; potassium uptake protein complement(1007504..1009075) Anaplasma marginale str. St. Maries 3171587 YP_154224.1 CDS mesJ NC_004842.2 1009146 1010651 D COG0037 MesJ predicted ATPase of the PP-loop superfamily implicated in cell cycle control; similar to NP_220436.1; cell cycle protein 1009146..1010651 Anaplasma marginale str. St. Maries 3170989 YP_154225.1 CDS ftsH NC_004842.2 1010664 1012496 D COG0465 HflB ATP-dependent Zn proteases; cell division protein 1010664..1012496 Anaplasma marginale str. St. Maries 3171852 YP_154226.2 CDS secA NC_004842.2 1012689 1015307 D functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1012689..1015307 Anaplasma marginale str. St. Maries 3171424 YP_154227.1 CDS AM1121 NC_004842.2 1015158 1015364 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(1015158..1015364) Anaplasma marginale str. St. Maries 3171828 YP_154228.1 CDS AM1122 NC_004842.2 1015383 1016132 R conserved hypothetical protein similar to NP_966776.1; hypothetical protein complement(1015383..1016132) Anaplasma marginale str. St. Maries 3171076 YP_154229.1 CDS czcD NC_004842.2 1016136 1017089 R COG1230 CzcD Co/Zn/Cd efflux system component; similar to NP_692320.1; cation efflux system protein complement(1016136..1017089) Anaplasma marginale str. St. Maries 3171727 YP_154230.1 CDS ccmB NC_004842.2 1017256 1017918 R COG2386 CcmB ABC-type transport system involved in cytochrome C biogenesis, permease component; heme exporter protein B complement(1017256..1017918) Anaplasma marginale str. St. Maries 3171194 YP_154231.1 CDS dksA NC_004842.2 1018019 1018432 D COG1734 DksA DnaK suppressor protein; dnaK suppressor protein 1018019..1018432 Anaplasma marginale str. St. Maries 3171679 YP_154232.1 CDS dtbS NC_004842.2 1018760 1019443 R COG0132 BioD dethiobiotin synthetase; dethiobiotin synthase complement(1018760..1019443) Anaplasma marginale str. St. Maries 3171175 YP_154233.1 CDS ftsY NC_004842.2 1019519 1020436 D COG0552 FtsY signal recognition particle GTPase; similar to NP_221126.1; cell division protein 1019519..1020436 Anaplasma marginale str. St. Maries 3171258 YP_154234.1 CDS icd NC_004842.2 1020711 1022177 D catalyzes the formation of 2-oxoglutarate from isocitrate; isocitrate dehydrogenase 1020711..1022177 Anaplasma marginale str. St. Maries 3171477 YP_154235.1 CDS recJ NC_004842.2 1022302 1024062 D COG0608 RecJ single-stranded DNA-specific exonuclease; similar to NP_220901.1; single-stranded-DNA-specific exonuclease 1022302..1024062 Anaplasma marginale str. St. Maries 3171567 YP_154236.1 CDS AM1135 NC_004842.2 1024037 1024336 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(1024037..1024336) Anaplasma marginale str. St. Maries 3171703 YP_154237.1 CDS pcnB NC_004842.2 1024527 1025786 D COG0617 PcnB tRNA nucleotidyltransferase/poly(A) polymerase; similar to NP_220410.1; poly (A) polymerase 1024527..1025786 Anaplasma marginale str. St. Maries 3171346 YP_154238.1 CDS ndk NC_004842.2 1025923 1026363 R catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase complement(1025923..1026363) Anaplasma marginale str. St. Maries 3170956 YP_154239.1 CDS AM1138 NC_004842.2 1026592 1027155 D similar to AAN08687.1; hypothetical protein 1026592..1027155 Anaplasma marginale str. St. Maries 3171283 YP_154240.1 CDS omp1 NC_004842.2 1027570 1028562 D member of msp2 superfamily; outer membrane protein 1 1027570..1028562 Anaplasma marginale str. St. Maries 3171108 YP_154241.1 CDS opag3 NC_004842.2 1028727 1029665 D member of msp2 superfamily; msp2 operon associated gene 3 1028727..1029665 Anaplasma marginale str. St. Maries 3171088 YP_154242.1 CDS AM1141 NC_004842.2 1028745 1029848 R hypothetical protein identified by Glimmer 2; known not to be transcribed; hypothetical protein complement(1028745..1029848) Anaplasma marginale str. St. Maries 3171417 YP_154243.1 CDS opag2 NC_004842.2 1029680 1030591 D member of msp2 superfamily; msp2 operon associated gene 2 1029680..1030591 Anaplasma marginale str. St. Maries 3171683 YP_154244.1 CDS opag1 NC_004842.2 1030615 1031007 D member of msp2 superfamily; msp2 operon associated gene 1 1030615..1031007 Anaplasma marginale str. St. Maries 3171689 YP_154245.1 CDS msp2 NC_004842.2 1031020 1032243 D similar to AAG31570.1; member of msp2 superfamily; major surface protein 2 1031020..1032243 Anaplasma marginale str. St. Maries 3171428 YP_154246.1 CDS AM1145 NC_004842.2 1032455 1032949 R conserved family - DnaJ domain protein; hypothetical protein complement(1032455..1032949) Anaplasma marginale str. St. Maries 3171388 YP_154247.1 CDS AM1146 NC_004842.2 1032906 1033490 D conserved family - nifU-like protein; hypothetical protein 1032906..1033490 Anaplasma marginale str. St. Maries 3171640 YP_154248.1 CDS orfX NC_004842.2 1034507 1034896 R other copies include: AM030, AM044, AM065, AM077 AM082, AM210, AM717, AM723, AM989, AM1061 and AM1253; member of msp2 superfamily; hypothetical protein complement(1034507..1034896) Anaplasma marginale str. St. Maries 3171597 YP_154249.1 CDS omp2 NC_004842.2 1038392 1039126 R member of msp2 superfamily; outer membrane protein 2 complement(1038392..1039126) Anaplasma marginale str. St. Maries 3171435 YP_154250.1 CDS omp3 NC_004842.2 1039207 1039857 R member of msp2 superfamily; outer membrane protein 3 complement(1039207..1039857) Anaplasma marginale str. St. Maries 3171320 YP_154251.1 CDS AM1161 NC_004842.2 1039827 1040150 D hypothetical protein identified by Glimmer 2; hypothetical protein 1039827..1040150 Anaplasma marginale str. St. Maries 3171401 YP_154252.1 CDS omp4 NC_004842.2 1040420 1041637 D member of msp2 superfamily; outer membrane protein 4 1040420..1041637 Anaplasma marginale str. St. Maries 3171062 YP_154253.1 CDS AM1165 NC_004842.2 1041615 1041863 D hypothetical protein identified by Glimmer 2; hypothetical protein 1041615..1041863 Anaplasma marginale str. St. Maries 3171050 YP_154254.1 CDS omp5 NC_004842.2 1041982 1043100 D member of msp2 superfamily; outer membrane protein 5 1041982..1043100 Anaplasma marginale str. St. Maries 3171054 YP_154255.1 CDS AM1168 NC_004842.2 1043468 1044283 R conserved hypothetical protein similar to NP_220844.1; hypothetical protein complement(1043468..1044283) Anaplasma marginale str. St. Maries 3171159 YP_154256.1 CDS ccmF NC_004842.2 1044334 1046256 R COG1138 CcmF cytochrome C biogenesis factor; cytochrome C-type biogenesis protein complement(1044334..1046256) Anaplasma marginale str. St. Maries 3171403 YP_154257.1 CDS valS NC_004842.2 1046615 1049086 D valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 1046615..1049086 Anaplasma marginale str. St. Maries 3171649 YP_154258.1 CDS smpB NC_004842.2 1049982 1050431 R binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein complement(1049982..1050431) Anaplasma marginale str. St. Maries 3171002 YP_154259.1 CDS ribA NC_004842.2 1050434 1051066 R COG0807 RibA GTP cyclohydrolase II; other copies include AM120 and AM1317; 3,4-dihydroxy-2-butanone 4-phosphate synthase complement(1050434..1051066) Anaplasma marginale str. St. Maries 3171126 YP_154260.1 CDS greA NC_004842.2 1051085 1051609 R COG0782 GreA transcription elongation factor; transcription elongation factor greA complement(1051085..1051609) Anaplasma marginale str. St. Maries 3171886 YP_154261.1 CDS atpA NC_004842.2 1051606 1053129 R produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha complement(1051606..1053129) Anaplasma marginale str. St. Maries 3171366 YP_154262.1 CDS atpH NC_004842.2 1053149 1053721 R COG0712 AtpH F0F1-type ATP synthase delta subunit (mitochondrial oligomycin sensitivity protein); ATP synthase subunit delta complement(1053149..1053721) Anaplasma marginale str. St. Maries 3171209 YP_154263.1 CDS AM1179 NC_004842.2 1054297 1054548 R conserved hypothetical protein similar to ZP_00211180.1; hypothetical protein complement(1054297..1054548) Anaplasma marginale str. St. Maries 3171006 YP_154264.1 CDS AM1180 NC_004842.2 1054552 1055790 R conserved hypothetical protein similar to NP_966944.1; hypothetical protein complement(1054552..1055790) Anaplasma marginale str. St. Maries 3171751 YP_154265.1 CDS AM1181 NC_004842.2 1055787 1056539 R conserved hypothetical protein similar to ZP_00211182.1; hypothetical protein complement(1055787..1056539) Anaplasma marginale str. St. Maries 3171072 YP_154266.1 CDS AM1183 NC_004842.2 1056544 1057770 R conserved family - ABC-transporter; hypothetical protein complement(1056544..1057770) Anaplasma marginale str. St. Maries 3171029 YP_154267.1 CDS AM1185 NC_004842.2 1058051 1059100 D conserved hypothetical protein similar to NP_966159.1; hypothetical protein 1058051..1059100 Anaplasma marginale str. St. Maries 3171040 YP_154268.1 CDS AM1186 NC_004842.2 1059095 1060324 R conserved hypothetical protein similar to ZP_00211185.1; hypothetical protein complement(1059095..1060324) Anaplasma marginale str. St. Maries 3171315 YP_154269.1 CDS gltA NC_004842.2 1060680 1061933 R COG0372 GltA citrate synthase; citrate synthase complement(1060680..1061933) Anaplasma marginale str. St. Maries 3171697 YP_154270.1 CDS guaA NC_004842.2 1061970 1063559 R contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase complement(1061970..1063559) Anaplasma marginale str. St. Maries 3171301 YP_154271.1 CDS AM1189 NC_004842.2 1063676 1063906 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(1063676..1063906) Anaplasma marginale str. St. Maries 3171932 YP_154272.1 CDS AM1191 NC_004842.2 1064038 1064433 D hypothetical protein identified by Glimmer 2; hypothetical protein 1064038..1064433 Anaplasma marginale str. St. Maries 3171396 YP_154273.1 CDS pdhC NC_004842.2 1065049 1066350 D COG0508 AceF dihydrolipoamide acyltransferases; branched-chain alpha-keto acid dehydrogenase E2 subunit 1065049..1066350 Anaplasma marginale str. St. Maries 3171630 YP_154274.1 CDS AM1193 NC_004842.2 1066507 1066761 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(1066507..1066761) Anaplasma marginale str. St. Maries 3171379 YP_154275.2 CDS fbaB NC_004842.2 1066669 1067568 D catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase 1066669..1067568 Anaplasma marginale str. St. Maries 3171203 YP_154276.1 CDS pbpA1 NC_004842.2 1067822 1069627 R COG0768 FtsI cell division protein FtsI/penicillin-binding protein 2; penicillin-binding protein complement(1067822..1069627) Anaplasma marginale str. St. Maries 3171934 YP_154277.1 CDS secF NC_004842.2 1069608 1070543 R forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF complement(1069608..1070543) Anaplasma marginale str. St. Maries 3171823 YP_154278.1 CDS AM1200 NC_004842.2 1070689 1071069 D conserved hypothetical protein similar to ZP_00211205.1; hypothetical protein 1070689..1071069 Anaplasma marginale str. St. Maries 3171223 YP_154279.1 CDS hemA NC_004842.2 1071072 1072304 R catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine; 5-aminolevulinate synthase complement(1071072..1072304) Anaplasma marginale str. St. Maries 3171220 YP_154280.1 CDS tyrS NC_004842.2 1072474 1073718 R COG0162 TyrS tyrosyl-tRNA synthetase; tyrosyl-tRNA synthetase complement(1072474..1073718) Anaplasma marginale str. St. Maries 3171475 YP_154281.1 CDS glnA NC_004842.2 1074028 1075434 D COG0174 GlnA glutamine synthase; other copies include: AM222; glutamine synthetase 1074028..1075434 Anaplasma marginale str. St. Maries 3171638 YP_154282.1 CDS mraY NC_004842.2 1075445 1076473 D First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 1075445..1076473 Anaplasma marginale str. St. Maries 3171695 YP_154283.1 CDS ispB NC_004842.2 1076483 1077466 D COG0142 IspA geranylgeranyl pyrophosphate synthase; octaprenyl-diphosphate synthase 1076483..1077466 Anaplasma marginale str. St. Maries 3171091 YP_154284.1 CDS AM1209 NC_004842.2 1077541 1079622 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(1077541..1079622) Anaplasma marginale str. St. Maries 3171192 YP_154285.1 CDS mkl NC_004842.2 1079749 1080468 R similar to NP_220490.1; ribonucleotide transport ATP-binding protein complement(1079749..1080468) Anaplasma marginale str. St. Maries 3171269 YP_154286.1 CDS AM1212 NC_004842.2 1080473 1081252 R conserved family - ABC-type transport protein; hypothetical protein complement(1080473..1081252) Anaplasma marginale str. St. Maries 3171735 YP_154287.1 CDS rpe NC_004842.2 1081271 1082053 R COG0036 Rpe pentose-5-phosphate-3-epimerase; similar to EAA23792.1; ribulose-phosphate 3-epimerase complement(1081271..1082053) Anaplasma marginale str. St. Maries 3171659 YP_154288.1 CDS polA NC_004842.2 1082130 1084724 R has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I complement(1082130..1084724) Anaplasma marginale str. St. Maries 3171300 YP_154289.1 CDS AM1216 NC_004842.2 1085541 1085927 D hypothetical protein identified by Glimmer 2; hypothetical protein 1085541..1085927 Anaplasma marginale str. St. Maries 3171593 YP_154290.1 CDS argF NC_004842.2 1085950 1086858 D COG0078 ArgF ornithine carbamoyltransferase; ornithine carbamoyltransferase 1085950..1086858 Anaplasma marginale str. St. Maries 3171415 YP_154291.1 CDS recF NC_004842.2 1086868 1087983 D Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 1086868..1087983 Anaplasma marginale str. St. Maries 3171185 YP_154292.1 CDS omp6 NC_004842.2 1087980 1088441 R member of msp2 superfamily; outer membrane protein 6 complement(1087980..1088441) Anaplasma marginale str. St. Maries 3171766 YP_154293.1 CDS omp7 NC_004842.2 1088481 1089671 R member of msp2 superfamily; outer membrane protein 7 complement(1088481..1089671) Anaplasma marginale str. St. Maries 3171690 YP_154294.1 CDS omp8 NC_004842.2 1089736 1090935 R member of msp2 superfamily; outer membrane protein 8 complement(1089736..1090935) Anaplasma marginale str. St. Maries 3171297 YP_154295.1 CDS omp9 NC_004842.2 1090999 1092210 R member of msp2 superfamily; outer membrane protein 9 complement(1090999..1092210) Anaplasma marginale str. St. Maries 3171490 YP_154296.1 CDS omp10 NC_004842.2 1092273 1093535 R member of msp2 superfamily; outer membrane protein 10 complement(1092273..1093535) Anaplasma marginale str. St. Maries 3171576 YP_154297.1 CDS AM1225 NC_004842.2 1093976 1094518 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(1093976..1094518) Anaplasma marginale str. St. Maries 3171182 YP_154298.1 CDS AM1226 NC_004842.2 1094876 1095514 D hypothetical protein identified by Glimmer 2; hypothetical protein 1094876..1095514 Anaplasma marginale str. St. Maries 3171041 YP_154299.1 CDS AM1228 NC_004842.2 1095979 1096902 R conserved hypothetical protein similar to NP_966513.1; hypothetical protein complement(1095979..1096902) Anaplasma marginale str. St. Maries 3171588 YP_154300.1 CDS mviN NC_004842.2 1097053 1098417 R COG0728 MviN uncharacterized membrane protein virulence factor; similar to NP_360535.1; virulence factor MVIN complement(1097053..1098417) Anaplasma marginale str. St. Maries 3171268 YP_154301.1 CDS lgt NC_004842.2 1098643 1099500 D transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 1098643..1099500 Anaplasma marginale str. St. Maries 3171230 YP_154302.1 CDS AM1232 NC_004842.2 1099740 1099955 D hypothetical protein identified by Glimmer 2; hypothetical protein 1099740..1099955 Anaplasma marginale str. St. Maries 3171614 YP_154303.2 CDS rpsT NC_004842.2 1100204 1100494 R binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 complement(1100204..1100494) Anaplasma marginale str. St. Maries 3171469 YP_154304.1 CDS plsC NC_004842.2 1100613 1101338 R COG0204 PlsC 1-acyl-sn-glycerol-3-phosphate acyltransferase; similar to NP_538993.1; 1-acyl-sn-glycerol-3-phosphate acyltransferase complement(1100613..1101338) Anaplasma marginale str. St. Maries 3171152 YP_154305.1 CDS def NC_004842.2 1101370 1101927 D COG0242 Def N-formylmethionyl-tRNA deformylase; N-formylmethionylaminoacyl-tRNA deformylase 1101370..1101927 Anaplasma marginale str. St. Maries 3171325 YP_154306.1 CDS AM1237 NC_004842.2 1102174 1103046 D conserved hypothetical protein similar to NP_221193.1; hypothetical protein 1102174..1103046 Anaplasma marginale str. St. Maries 3170983 YP_154307.1 CDS AM1238 NC_004842.2 1103188 1103916 D hypothetical protein identified by Glimmer 2; hypothetical protein 1103188..1103916 Anaplasma marginale str. St. Maries 3171646 YP_154308.1 CDS AM1239 NC_004842.2 1104007 1104234 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(1104007..1104234) Anaplasma marginale str. St. Maries 3171681 YP_154309.1 CDS AM1240 NC_004842.2 1104293 1104499 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(1104293..1104499) Anaplasma marginale str. St. Maries 3171342 YP_154310.1 CDS AM1241 NC_004842.2 1104735 1105244 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(1104735..1105244) Anaplasma marginale str. St. Maries 3171117 YP_154311.1 CDS AM1242 NC_004842.2 1105289 1106398 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(1105289..1106398) Anaplasma marginale str. St. Maries 3171885 YP_154312.1 CDS uvrB NC_004842.2 1106811 1108766 R The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B complement(1106811..1108766) Anaplasma marginale str. St. Maries 3171348 YP_154313.1 CDS secD NC_004842.2 1108831 1110336 D part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 1108831..1110336 Anaplasma marginale str. St. Maries 3171468 YP_154314.1 CDS AM1248 NC_004842.2 1110826 1112649 D hypothetical protein identified by Glimmer 2; hypothetical protein 1110826..1112649 Anaplasma marginale str. St. Maries 3171437 YP_154315.1 CDS orfY NC_004842.2 1113315 1113548 D other copies include: AM032, AM046, AM063, AM721 AM990 and AM1059; member of msp2 superfamily; hypothetical protein 1113315..1113548 Anaplasma marginale str. St. Maries 3171280 YP_154316.1 CDS orfX NC_004842.2 1113621 1114010 D other copies include: AM030, AM044, AM065, AM077 AM082, AM210, AM717, AM723, AM989, AM1061 and AM1149; member of msp2 superfamily; hypothetical protein 1113621..1114010 Anaplasma marginale str. St. Maries 3171416 YP_154317.1 CDS AM1254 NC_004842.2 1114075 1115559 R conserved family - 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; hypothetical protein complement(1114075..1115559) Anaplasma marginale str. St. Maries 3171911 YP_154318.1 CDS omp11 NC_004842.2 1115669 1116658 R member of msp2 superfamily; outer membrane protein 11 complement(1115669..1116658) Anaplasma marginale str. St. Maries 3171237 YP_154319.1 CDS omp12 NC_004842.2 1116852 1117709 R member of msp2 superfamily; outer membrane protein 12 complement(1116852..1117709) Anaplasma marginale str. St. Maries 3171894 YP_154320.1 CDS omp13 NC_004842.2 1117917 1118975 R member of msp2 superfamily; outer membrane protein 13 complement(1117917..1118975) Anaplasma marginale str. St. Maries 3171876 YP_154321.1 CDS ftsZ NC_004842.2 1119261 1120514 D GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1119261..1120514 Anaplasma marginale str. St. Maries 3171446 YP_154322.1 CDS AM1264 NC_004842.2 1120891 1121355 D conserved hypothetical protein similar to NP_966484.1; hypothetical protein 1120891..1121355 Anaplasma marginale str. St. Maries 3171818 YP_154323.1 CDS parA NC_004842.2 1121429 1122244 D COG1192 Soj ATPases involved in chromosome partitioning; similar to NP_699034.1; chromosome partitioning protein 1121429..1122244 Anaplasma marginale str. St. Maries 3171658 YP_154324.1 CDS parB NC_004842.2 1122241 1123068 D COG1475 Spo0J predicted transcriptional regulators; similar to NP_105340.1; chromosome partitioning protein 1122241..1123068 Anaplasma marginale str. St. Maries 3171118 YP_154325.1 CDS rimM NC_004842.2 1123080 1123652 D Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1123080..1123652 Anaplasma marginale str. St. Maries 3171799 YP_154326.1 CDS trmD NC_004842.2 1123649 1124356 D methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1123649..1124356 Anaplasma marginale str. St. Maries 3171393 YP_154327.1 CDS rplS NC_004842.2 1124349 1124753 D this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1124349..1124753 Anaplasma marginale str. St. Maries 3171273 YP_154328.1 CDS cinA NC_004842.2 1124760 1125281 R COG1058 CinA predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; competence / damage-inducible protein complement(1124760..1125281) Anaplasma marginale str. St. Maries 3171465 YP_154329.1 CDS thrS NC_004842.2 1125347 1127257 D catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 1125347..1127257 Anaplasma marginale str. St. Maries 3171409 YP_154330.1 CDS infC NC_004842.2 1127287 1127820 D COG0290 InfC translation initiation factor IF3; translation initiation factor IF-3 1127287..1127820 Anaplasma marginale str. St. Maries 3171173 YP_154331.1 CDS AM1275 NC_004842.2 1128227 1128682 R conserved hypothetical protein similar to ZP_00142507.1; hypothetical protein complement(1128227..1128682) Anaplasma marginale str. St. Maries 3170976 YP_154332.1 CDS AM1276 NC_004842.2 1128686 1129387 R conserved family - integral membrane protein; hypothetical protein complement(1128686..1129387) Anaplasma marginale str. St. Maries 3171514 YP_154333.1 CDS asd NC_004842.2 1129505 1130515 R COG0136 Asd aspartate-semialdehyde dehydrogenase; aspartate-semialdehyde dehydrogenase complement(1129505..1130515) Anaplasma marginale str. St. Maries 3171694 YP_154334.1 CDS AM1278 NC_004842.2 1130517 1130825 R conserved hypothetical protein similar to NP_966784.1; hypothetical protein complement(1130517..1130825) Anaplasma marginale str. St. Maries 3171622 YP_154335.1 CDS dnaZ NC_004842.2 1130831 1132255 R COG2812 DnaX DNA polymerase III, gamma/tau subunits; DNA polymerase III subunit gamma complement(1130831..1132255) Anaplasma marginale str. St. Maries 3171860 YP_154336.1 CDS gapB NC_004842.2 1132441 1133445 R COG0057 GapA glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; NAD(P)-dependent glyceraldehyde 3-phosphate dehydrogenase complement(1132441..1133445) Anaplasma marginale str. St. Maries 3171594 YP_154337.1 CDS AM1285 NC_004842.2 1133834 1134778 D hypothetical protein identified by Glimmer 2; hypothetical protein 1133834..1134778 Anaplasma marginale str. St. Maries 3171565 YP_154338.1 CDS AM1286 NC_004842.2 1134794 1135450 D conserved hypothetical protein similar to NP_755835.1; isoprenoid biosynthesis protein 1134794..1135450 Anaplasma marginale str. St. Maries 3171025 YP_154339.1 CDS ftsW NC_004842.2 1135475 1136632 R COG0772 FtsW bacterial cell division membrane protein; similar to NP_220792.1; cell division protein complement(1135475..1136632) Anaplasma marginale str. St. Maries 3171056 YP_154340.1 CDS metK NC_004842.2 1136614 1137816 R methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase complement(1136614..1137816) Anaplasma marginale str. St. Maries 3171225 YP_154341.1 CDS ubiH NC_004842.2 1138038 1139204 D COG0654 UbiH 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; similar to NP_539083.1; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 1138038..1139204 Anaplasma marginale str. St. Maries 3171368 YP_154342.1 CDS AM1292 NC_004842.2 1139216 1139824 R conserved hypothetical protein similar to ZP_00211261.1; hypothetical protein complement(1139216..1139824) Anaplasma marginale str. St. Maries 3171512 YP_154343.1 CDS glyQ NC_004842.2 1140100 1140951 D glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 1140100..1140951 Anaplasma marginale str. St. Maries 3171725 YP_154344.1 CDS glyS NC_004842.2 1140953 1143037 D COG0751 GlyS glycyl-tRNA synthetase, beta subunit; glycyl-tRNA synthetase subunit beta 1140953..1143037 Anaplasma marginale str. St. Maries 3171151 YP_154345.1 CDS dnaJ NC_004842.2 1143119 1144258 D chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 1143119..1144258 Anaplasma marginale str. St. Maries 3171214 YP_154346.1 CDS nadC NC_004842.2 1144277 1145095 R COG0157 NadC nicotinate-nucleotide pyrophosphorylase; nicotinate-nucleotide pyrophosphorylase complement(1144277..1145095) Anaplasma marginale str. St. Maries 3171719 YP_154347.1 CDS AM1298 NC_004842.2 1145154 1145750 D conserved hypothetical protein similar to NP_966768.1; membrane protein 1145154..1145750 Anaplasma marginale str. St. Maries 3170955 YP_154348.1 CDS ruvC NC_004842.2 1145742 1146239 R COG0817 RuvC holliday junction resolvasome endonuclease subunit; holliday (crossover) junction endodeoxyribonuclease complement(1145742..1146239) Anaplasma marginale str. St. Maries 3171761 YP_154349.1 CDS coxC NC_004842.2 1146258 1147076 R COG1845 CyoC heme/copper-type cytochrome/quinol oxidase subunit 3; cytochrome C oxidase subunit III complement(1146258..1147076) Anaplasma marginale str. St. Maries 3171057 YP_154350.1 CDS hemE NC_004842.2 1147146 1147943 R COG0407 HemE uroporphyrinogen-III decarboxylase; uroporphyrinogen decarboxylase complement(1147146..1147943) Anaplasma marginale str. St. Maries 3171819 YP_154351.1 CDS AM1303 NC_004842.2 1148564 1149445 D conserved family - hemolysin; hypothetical protein 1148564..1149445 Anaplasma marginale str. St. Maries 3171261 YP_154352.1 CDS AM1304 NC_004842.2 1149432 1149950 R COG3740 - phage head maturation protease; hypothetical protein complement(1149432..1149950) Anaplasma marginale str. St. Maries 3171425 YP_154353.2 CDS AM1305 NC_004842.2 1149934 1151130 R hypothetical protein complement(1149934..1151130) Anaplasma marginale str. St. Maries 3171502 YP_154354.1 CDS AM1306 NC_004842.2 1151233 1152033 D conserved family - biotin synthesis protein; hypothetical protein 1151233..1152033 Anaplasma marginale str. St. Maries 3170993 YP_154355.1 CDS nadA NC_004842.2 1152053 1153009 D 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 1152053..1153009 Anaplasma marginale str. St. Maries 3171440 YP_154356.1 CDS fdxA NC_004842.2 1153031 1153402 R COG1145 NapF ferredoxin 2; similar to NP_539195.1; ferredoxin II complement(1153031..1153402) Anaplasma marginale str. St. Maries 3171436 YP_154357.1 CDS ilvC NC_004842.2 1153528 1154499 D catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 1153528..1154499 Anaplasma marginale str. St. Maries 3171071 YP_154358.1 CDS infC NC_004842.2 1154526 1154783 R COG0290 InfC translation initiation factor IF3; translation initiation factor IF-3 complement(1154526..1154783) Anaplasma marginale str. St. Maries 3171763 YP_154359.1 CDS virD4 NC_004842.2 1154957 1157377 R COG3505 VirD4 type IV secretory pathway, VirD4 components; similar to AAM00422.1; type IV secretion system protein VirB8 complement(1154957..1157377) Anaplasma marginale str. St. Maries 3171164 YP_154360.1 CDS virB11 NC_004842.2 1157425 1158438 R COG0630 VirB11 type IV secretory pathway VirB11 components, and related ATPases involved in; similar to AAM00419.1; type IV secretion system ATPase VirB11 complement(1157425..1158438) Anaplasma marginale str. St. Maries 3171174 YP_154361.1 CDS virB10 NC_004842.2 1158480 1159817 R COG2948 VirB10 type IV secretory pathway VirB10 components; similar to AAM00418.1; VirB10 protein complement(1158480..1159817) Anaplasma marginale str. St. Maries 3171939 YP_154362.1 CDS virB9 NC_004842.2 1159825 1160664 R COG3504 VirB9 type IV secretory pathway, VirB9 components; similar to AAM00421.1; VirB9 protein complement(1159825..1160664) Anaplasma marginale str. St. Maries 3171330 YP_154363.1 CDS virB8 NC_004842.2 1160651 1161340 R COG3736 VirB8 type IV secretion system component VirB8; VirB8 protein complement(1160651..1161340) Anaplasma marginale str. St. Maries 3171196 YP_154364.1 CDS ribA NC_004842.2 1161459 1162592 R COG0807 RibA GTP cyclohydrolase II; other copies include AM120 and AM1172; GTP cyclohydrolase II complement(1161459..1162592) Anaplasma marginale str. St. Maries 3171620 YP_154365.1 CDS AM1319 NC_004842.2 1162709 1163950 R conserved family - TPR domain protein; hypothetical protein complement(1162709..1163950) Anaplasma marginale str. St. Maries 3171199 YP_154366.1 CDS AM1320 NC_004842.2 1163892 1164419 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(1163892..1164419) Anaplasma marginale str. St. Maries 3171827 YP_154367.1 CDS dapF NC_004842.2 1164480 1165313 R COG0253 DapF diaminopimelate epimerase; diaminopimelate epimerase complement(1164480..1165313) Anaplasma marginale str. St. Maries 3171361 YP_154368.1 CDS AM1324 NC_004842.2 1165325 1166041 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(1165325..1166041) Anaplasma marginale str. St. Maries 3171789 YP_154369.1 CDS AM1325 NC_004842.2 1166183 1166611 R conserved hypothetical protein similar to ZP_00211235.1; hypothetical protein complement(1166183..1166611) Anaplasma marginale str. St. Maries 3171929 YP_154370.1 CDS pgk NC_004842.2 1167047 1168204 D Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 1167047..1168204 Anaplasma marginale str. St. Maries 3171245 YP_154371.1 CDS xseA NC_004842.2 1168396 1169589 R COG1570 XseA exonuclease VII, large subunit; exodeoxyribonuclease large subunit complement(1168396..1169589) Anaplasma marginale str. St. Maries 3171575 YP_154372.1 CDS AM1328 NC_004842.2 1169564 1170232 R conserved hypothetical protein similar to ZP_00211231.1; hypothetical protein complement(1169564..1170232) Anaplasma marginale str. St. Maries 3171688 YP_154373.2 CDS dapD NC_004842.2 1170411 1171247 D catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 1170411..1171247 Anaplasma marginale str. St. Maries 3171769 YP_154374.1 CDS trmE NC_004842.2 1171248 1172579 D in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1171248..1172579 Anaplasma marginale str. St. Maries 3171089 YP_154375.1 CDS dfp NC_004842.2 1172736 1173293 R decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine.; phosphopantothenoylcysteine decarboxylase complement(1172736..1173293) Anaplasma marginale str. St. Maries 3171740 YP_154376.1 CDS recG NC_004842.2 1173303 1175402 D COG1200 RecG RecG-like helicases; similar to NP_699765.1; ATP-dependent DNA helicase 1173303..1175402 Anaplasma marginale str. St. Maries 3171251 YP_154377.1 CDS AM1337 NC_004842.2 1175585 1176565 D conserved family - NADH-ubiquinone oxidoreductase; hypothetical protein 1175585..1176565 Anaplasma marginale str. St. Maries 3171730 YP_154378.1 CDS purF NC_004842.2 1176700 1178109 R Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase complement(1176700..1178109) Anaplasma marginale str. St. Maries 3171875 YP_154379.1 CDS pth NC_004842.2 1178260 1178820 R Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase complement(1178260..1178820) Anaplasma marginale str. St. Maries 3171042 YP_154380.1 CDS rplY NC_004842.2 1178825 1179481 R the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25/general stress protein Ctc complement(1178825..1179481) Anaplasma marginale str. St. Maries 3171385 YP_154381.1 CDS AM1341 NC_004842.2 1179523 1179741 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(1179523..1179741) Anaplasma marginale str. St. Maries 3171632 YP_154382.1 CDS AM1346 NC_004842.2 1183255 1184004 R conserved family - competence protein F; hypothetical protein complement(1183255..1184004) Anaplasma marginale str. St. Maries 3171859 YP_154383.1 CDS dapE NC_004842.2 1183943 1185145 R dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase complement(1183943..1185145) Anaplasma marginale str. St. Maries 3171795 YP_154384.1 CDS kefB NC_004842.2 1185315 1187006 R COG0475 KefB Kef-type K+ transport systems membrane components; similar to AAL24515.1; glutathione-regulated potassium-efflux system protein complement(1185315..1187006) Anaplasma marginale str. St. Maries 3170949 YP_154385.1 CDS AM1349 NC_004842.2 1187020 1187583 R conserved hypothetical protein similar to NP_966962.1; hypothetical protein complement(1187020..1187583) Anaplasma marginale str. St. Maries 3171698 YP_154386.1 CDS AM1350 NC_004842.2 1187811 1188257 R conserved hypothetical protein similar to NP_221229.1; hypothetical protein complement(1187811..1188257) Anaplasma marginale str. St. Maries 3171429 YP_154387.1 CDS pdhB NC_004842.2 1188388 1189413 R catalyzes the oxidative decarboxylation of pyruvate with concomitant acetylation of a lipoic acid-containing dihydrolipoamide acyltransferase within the complex. The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2); it contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase; pyruvate dehydrogenase subunit beta complement(1188388..1189413) Anaplasma marginale str. St. Maries 3171595 YP_154388.1 CDS AM1352 NC_004842.2 1189478 1192339 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(1189478..1192339) Anaplasma marginale str. St. Maries 3171363 YP_154389.1 CDS tldD NC_004842.2 1192852 1194273 D COG0312 TldD predicted Zn-dependent proteases and their inactivated homologs; similar to NP_531465.1; tldD protein 1192852..1194273 Anaplasma marginale str. St. Maries 3171360 YP_154390.1 CDS AM1354 NC_004842.2 1194357 1194593 R hypothetical protein identified by Glimmer 2; hypothetical protein complement(1194357..1194593) Anaplasma marginale str. St. Maries 3171851 YP_154391.1 CDS AM1355 NC_004842.2 1194703 1195797 R translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD complement(1194703..1195797) Anaplasma marginale str. St. Maries 3171762 YP_154392.1 CDS ispF NC_004842.2 1195978 1196568 R COG0245 IspF 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; similar to NP_755192.1; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase complement(1195978..1196568) Anaplasma marginale str. St. Maries 3171481 YP_154393.1 CDS ispD NC_004842.2 1196596 1197306 R COG1211 IspD 4-diphosphocytidyl-2-methyl-D-erithritol synthase; similar to NP_698125.1; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase complement(1196596..1197306) Anaplasma marginale str. St. Maries 3170964 tRNA-Pro-1 tRNA tRNA-Pro-1 NC_004842.2 4916 4993 D tRNA-Pro 4916..4993 Anaplasma marginale str. St. Maries 3171711 tRNA-Ser-1 tRNA tRNA-Ser-1 NC_004842.2 6822 6908 D tRNA-Ser 6822..6908 Anaplasma marginale str. St. Maries 3171941 tRNA-His-1 tRNA tRNA-His-1 NC_004842.2 30979 31051 D tRNA-His 30979..31051 Anaplasma marginale str. St. Maries 3171482 tRNA-Ala-1 tRNA tRNA-Ala-1 NC_004842.2 61301 61373 R tRNA-Ala complement(61301..61373) Anaplasma marginale str. St. Maries 3171073 tRNA-Val-1 tRNA tRNA-Val-1 NC_004842.2 153914 153989 R tRNA-Val complement(153914..153989) Anaplasma marginale str. St. Maries 3170959 tRNA-Trp-1 tRNA tRNA-Trp-1 NC_004842.2 212711 212784 R tRNA-Trp complement(212711..212784) Anaplasma marginale str. St. Maries 3171407 tRNA-Arg-1 tRNA tRNA-Arg-1 NC_004842.2 229502 229575 R tRNA-Arg complement(229502..229575) Anaplasma marginale str. St. Maries 3171924 tRNA-Leu-1 tRNA tRNA-Leu-1 NC_004842.2 256088 256173 R tRNA-Leu complement(256088..256173) Anaplasma marginale str. St. Maries 3171133 tRNA-Lys-1 tRNA tRNA-Lys-1 NC_004842.2 259474 259543 R tRNA-Lys complement(259474..259543) Anaplasma marginale str. St. Maries 3171212 tRNA-Leu-2 tRNA tRNA-Leu-2 NC_004842.2 259675 259757 R tRNA-Leu complement(259675..259757) Anaplasma marginale str. St. Maries 3171166 tRNA-Met-1 tRNA tRNA-Met-1 NC_004842.2 265796 265868 R tRNA-Met complement(265796..265868) Anaplasma marginale str. St. Maries 3170963 tRNA-Gly-1 tRNA tRNA-Gly-1 NC_004842.2 339807 339878 R tRNA-Gly complement(339807..339878) Anaplasma marginale str. St. Maries 3171785 tRNA-Gly-2 tRNA tRNA-Gly-2 NC_004842.2 339934 340005 R tRNA-Gly complement(339934..340005) Anaplasma marginale str. St. Maries 3171899 tRNA-Asp-1 tRNA tRNA-Asp-1 NC_004842.2 388354 388427 R tRNA-Asp complement(388354..388427) Anaplasma marginale str. St. Maries 3171883 tRNA-Asn-1 tRNA tRNA-Asn-1 NC_004842.2 459905 459976 R tRNA-Asn complement(459905..459976) Anaplasma marginale str. St. Maries 3170981 tRNA-Phe-1 tRNA tRNA-Phe-1 NC_004842.2 463417 463487 R tRNA-Phe complement(463417..463487) Anaplasma marginale str. St. Maries 3171843 tRNA-Arg-2 tRNA tRNA-Arg-2 NC_004842.2 473076 473149 R tRNA-Arg complement(473076..473149) Anaplasma marginale str. St. Maries 3171793 tRNA-Ser-2 tRNA tRNA-Ser-2 NC_004842.2 516769 516860 R tRNA-Ser complement(516769..516860) Anaplasma marginale str. St. Maries 3171096 tRNA-Thr-1 tRNA tRNA-Thr-1 NC_004842.2 518359 518432 R tRNA-Thr complement(518359..518432) Anaplasma marginale str. St. Maries 3171759 tRNA-Met-2 tRNA tRNA-Met-2 NC_004842.2 537017 537091 R tRNA-Met complement(537017..537091) Anaplasma marginale str. St. Maries 3171821 tRNA-Ile-1 tRNA tRNA-Ile-1 NC_004842.2 542494 542569 R tRNA-Ile complement(542494..542569) Anaplasma marginale str. St. Maries 3171264 tRNA-Leu-3 tRNA tRNA-Leu-3 NC_004842.2 605594 605676 R tRNA-Leu complement(605594..605676) Anaplasma marginale str. St. Maries 3171265 tRNA-Pro-2 tRNA tRNA-Pro-2 NC_004842.2 607462 607535 R tRNA-Pro complement(607462..607535) Anaplasma marginale str. St. Maries 3171350 tRNA-Thr-2 tRNA tRNA-Thr-2 NC_004842.2 705062 705135 R tRNA-Thr complement(705062..705135) Anaplasma marginale str. St. Maries 3170998 tRNA-Arg-3 tRNA tRNA-Arg-3 NC_004842.2 754892 754966 R tRNA-Arg complement(754892..754966) Anaplasma marginale str. St. Maries 3171343 tRNA-Glu-1 tRNA tRNA-Glu-1 NC_004842.2 794916 794988 R tRNA-Glu complement(794916..794988) Anaplasma marginale str. St. Maries 3171634 tRNA-Gly-3 tRNA tRNA-Gly-3 NC_004842.2 833419 833489 R tRNA-Gly complement(833419..833489) Anaplasma marginale str. St. Maries 3170984 tRNA-Tyr-1 tRNA tRNA-Tyr-1 NC_004842.2 833498 833580 R tRNA-Tyr complement(833498..833580) Anaplasma marginale str. St. Maries 3171267 tRNA-Ser-3 tRNA tRNA-Ser-3 NC_004842.2 1009196 1009280 R tRNA-Ser complement(1009196..1009280) Anaplasma marginale str. St. Maries 3171931 tRNA-Val-2 tRNA tRNA-Val-2 NC_004842.2 1017048 1017120 R tRNA-Val complement(1017048..1017120) Anaplasma marginale str. St. Maries 3171771 tRNA-Cys-1 tRNA tRNA-Cys-1 NC_004842.2 1067571 1067642 R tRNA-Cys complement(1067571..1067642) Anaplasma marginale str. St. Maries 3171376 tRNA-Lys-2 tRNA tRNA-Lys-2 NC_004842.2 1073752 1073823 R tRNA-Lys complement(1073752..1073823) Anaplasma marginale str. St. Maries 3170967 tRNA-Arg-4 tRNA tRNA-Arg-4 NC_004842.2 1137941 1138018 R tRNA-Arg complement(1137941..1138018) Anaplasma marginale str. St. Maries 3171327 tRNA-Gln-1 tRNA tRNA-Gln-1 NC_004842.2 1139858 1139929 R tRNA-Gln complement(1139858..1139929) Anaplasma marginale str. St. Maries 3171098 tRNA-Leu-4 tRNA tRNA-Leu-4 NC_004842.2 1162563 1162651 R tRNA-Leu complement(1162563..1162651) Anaplasma marginale str. St. Maries 3171786 tRNA-Met-3 tRNA tRNA-Met-3 NC_004842.2 1183118 1183194 R tRNA-Met complement(1183118..1183194) Anaplasma marginale str. St. Maries 3171881 tRNA-Leu-5 tRNA tRNA-Leu-5 NC_004842.2 1192658 1192741 R tRNA-Leu complement(1192658..1192741) Anaplasma marginale str. St. Maries 3171625 AMr1 rRNA AMr1 NC_004842.2 81179 83945 D 23S ribosomal RNA 81179..83945 Anaplasma marginale str. St. Maries 4794252 AMr2 rRNA AMr2 NC_004842.2 84031 84151 D 5S ribosomal RNA 84031..84151 Anaplasma marginale str. St. Maries 4794251 AMr3 rRNA AMr3 NC_004842.2 247468 248989 D 16S ribosomal RNA 247468..248989 Anaplasma marginale str. St. Maries 4794250