-- dump date 20140618_204239 -- class Genbank::CDS -- table cds -- table main -- field 1 id -- field 2 GI -- field 3 GeneID -- field 4 chrom_position -- field 5 chromosome -- field 6 codon_start -- field 7 contig -- field 8 description -- field 9 end_pos -- field 10 gene -- field 11 gene_id -- field 12 name -- field 13 organism -- field 14 product -- field 15 protein_id -- field 16 start_pos -- field 17 strand -- field 18 taxid -- field 19 type -- header -- id GI GeneID chrom_position chromosome codon_start contig description end_pos gene gene_id name organism product protein_id start_pos strand taxid type YP_153445.1 56416371 3171015 1..1905 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 1905 3171015 AM1359 Anaplasma marginale str. St. Maries hypothetical protein YP_153445.1 1 D 234826 CDS YP_153446.1 56416372 3171371 complement(1862..2362) 1 NC_004842.2 COG0026 phosphoribosylaminoimidazole carboxylase (NCAIR synthetase); phosphoribosylaminoimidazole carboxylase catalytic subunit 2362 purE 3171371 purE Anaplasma marginale str. St. Maries phosphoribosylaminoimidazole carboxylase catalytic subunit YP_153446.1 1862 R 234826 CDS YP_153447.1 56416373 3171684 complement(2355..2957) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00211153.1; hypothetical protein 2957 3171684 AM002 Anaplasma marginale str. St. Maries hypothetical protein YP_153447.1 2355 R 234826 CDS YP_153448.1 56416374 3171340 3113..4183 1 NC_004842.2 COG0772 FtsW bacterial cell division membrane protein; similar to NP_220664.1; rod shape determining protein 4183 rodA 3171340 rodA Anaplasma marginale str. St. Maries rod shape determining protein YP_153448.1 3113 D 234826 CDS YP_153449.1 56416375 3171562 4258..4554 1 NC_004842.2 conserved family - DNA binding protein; hypothetical protein 4554 3171562 AM006 Anaplasma marginale str. St. Maries hypothetical protein YP_153449.1 4258 D 234826 CDS YP_153450.1 56416376 3171137 4551..4925 1 NC_004842.2 conserved family - transcriptional regulator; hypothetical protein 4925 3171137 AM007 Anaplasma marginale str. St. Maries hypothetical protein YP_153450.1 4551 D 234826 CDS YP_153451.1 56416377 3171867 complement(5187..6119) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 6119 3171867 AM008 Anaplasma marginale str. St. Maries hypothetical protein YP_153451.1 5187 R 234826 CDS YP_153452.1 56416378 3171817 complement(6209..6619) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 6619 3171817 AM009 Anaplasma marginale str. St. Maries hypothetical protein YP_153452.1 6209 R 234826 CDS YP_153453.1 56416379 3171582 6921..7544 1 NC_004842.2 COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes; open reading frame split domain with AM011; UDP-N-acetylmuramate-alanine ligase 7544 murC 3171582 murC Anaplasma marginale str. St. Maries UDP-N-acetylmuramate-alanine ligase YP_153453.1 6921 D 234826 CDS YP_153454.1 56416380 3171005 7532..8368 1 NC_004842.2 COG1181 D-alanine-D-alanine ligase and related ATP-grasp enzymes; open reading frame split domain with AM010; UDP-N-acetylmuramate-alanine ligase 8368 murC 3171005 murC Anaplasma marginale str. St. Maries UDP-N-acetylmuramate-alanine ligase YP_153454.1 7532 D 234826 CDS YP_153455.1 56416381 3171357 complement(8395..9384) 1 NC_004842.2 COG0180 trpS tryptophanyl-tRNA synthetase; tryptophanyl-tRNA synthetase 9384 trpS 3171357 trpS Anaplasma marginale str. St. Maries tryptophanyl-tRNA synthetase YP_153455.1 8395 R 234826 CDS YP_153456.1 56416382 3171329 complement(9381..9875) 1 NC_004842.2 COG0576 GrpE molecular chaperone GrpE (heat shock protein); GRPE protein 9875 grpE 3171329 grpE Anaplasma marginale str. St. Maries GRPE protein YP_153456.1 9381 R 234826 CDS YP_153457.1 56416383 3171598 10097..11212 1 NC_004842.2 COG0117 RibD pyrimidine deaminase; riboflavin biosynthesis protein 11212 ribD 3171598 ribD Anaplasma marginale str. St. Maries riboflavin biosynthesis protein YP_153457.1 10097 D 234826 CDS YP_153458.1 56416384 3171313 complement(11486..13168) 1 NC_004842.2 CTP synthase; CTP synthase; cytidine triphosphate synthetase; catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen; in Escherichia coli this enzyme forms a homotetramer; CTP synthetase 13168 pyrG 3171313 pyrG Anaplasma marginale str. St. Maries CTP synthetase YP_153458.1 11486 R 234826 CDS YP_153459.1 56416385 3171139 complement(13181..13510) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00211144.1; preprotein translocase subunit SecG 13510 secG 3171139 secG Anaplasma marginale str. St. Maries preprotein translocase subunit SecG YP_153459.1 13181 R 234826 CDS YP_153460.1 56416386 3171666 13686..13946 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 13946 3171666 AM020 Anaplasma marginale str. St. Maries hypothetical protein YP_153460.1 13686 D 234826 CDS YP_153461.1 56416387 3170978 13939..14877 1 NC_004842.2 COG0582 XerC integrase; integrase/recombinase 14877 xerD 3170978 xerD Anaplasma marginale str. St. Maries integrase/recombinase YP_153461.1 13939 D 234826 CDS YP_153462.1 56416388 3171442 complement(15075..15749) 1 NC_004842.2 COG1136 PhnL ABC-type transport systems involved in lipoprotein release, ATPase components; similar to NP_102951.1; ATP transporter ATP-binding protein 15749 phnL 3171442 phnL Anaplasma marginale str. St. Maries ATP transporter ATP-binding protein YP_153462.1 15075 R 234826 CDS YP_153463.1 56416389 3171619 16020..18272 1 NC_004842.2 NADP-dependent; catalyzes the oxidative decarboxylation of malate to form pyruvate; decarboxylates oxaloacetate; malic enzyme 18272 maeB 3171619 maeB Anaplasma marginale str. St. Maries malic enzyme YP_153463.1 16020 D 234826 CDS YP_153464.1 56416390 3171915 18446..21166 1 NC_004842.2 conserved family - exoprotein involved in heme utilization or adhesion; hypothetical protein 21166 3171915 AM025 Anaplasma marginale str. St. Maries hypothetical protein YP_153464.1 18446 D 234826 CDS YP_153465.1 56416391 3171686 21386..22900 1 NC_004842.2 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; monovalent cation/H+ antiporter subunit D 22900 3171686 AM026 Anaplasma marginale str. St. Maries monovalent cation/H+ antiporter subunit D YP_153465.1 21386 D 234826 CDS YP_153466.1 56416392 3171061 complement(22915..23301) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 23301 3171061 AM027 Anaplasma marginale str. St. Maries hypothetical protein YP_153466.1 22915 R 234826 CDS YP_153467.1 56416393 3171600 complement(23496..23882) 1 NC_004842.2 other copies include: AM044, AM065, AM077, AM082 AM210, AM717, AM723, AM989, AM1061, AM1149 and AM1253; member of msp2 superfamily; hypothetical protein 23882 orfX 3171600 orfX Anaplasma marginale str. St. Maries hypothetical protein YP_153467.1 23496 R 234826 CDS YP_153468.1 56416394 3171579 complement(23955..24188) 1 NC_004842.2 other copies include: AM046, AM063, AM721, AM990 AM1059 and AM1251; member of msp2 superfamily; hypothetical protein 24188 orfY 3171579 orfY Anaplasma marginale str. St. Maries hypothetical protein YP_153468.1 23955 R 234826 CDS YP_153469.1 56416395 3171715 complement(25004..27445) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 27445 3171715 AM034 Anaplasma marginale str. St. Maries hypothetical protein YP_153469.1 25004 R 234826 CDS YP_153470.1 56416396 3171573 27643..27852 1 NC_004842.2 conserved hypothetical protein similar to ZP_00220026.1; hypothetical protein 27852 3171573 AM035 Anaplasma marginale str. St. Maries hypothetical protein YP_153470.1 27643 D 234826 CDS YP_153471.1 56416397 3171499 27915..28709 1 NC_004842.2 functions in thiamine (vitamin B1) biosynthesis; in Bacillus subtilis this enzyme catalyzes the formation of thiazole from dehydroxyglycine and 1-deoxy-D-xylulose-5-phosphate and ThiS-thiocarboxylate; thiazole synthase 28709 thiG 3171499 thiG Anaplasma marginale str. St. Maries thiazole synthase YP_153471.1 27915 D 234826 CDS YP_153472.1 56416398 3171078 complement(28807..29247) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 29247 3171078 AM038 Anaplasma marginale str. St. Maries hypothetical protein YP_153472.1 28807 R 234826 CDS YP_153473.1 56416399 3171397 29429..30754 1 NC_004842.2 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 30754 gltX 3171397 gltX Anaplasma marginale str. St. Maries glutamyl-tRNA synthetase YP_153473.1 29429 D 234826 CDS YP_153474.1 56416400 3171352 31186..32391 1 NC_004842.2 conserved hypothetical protein similar to ZP_00012590.1; hypothetical protein 32391 3171352 AM041 Anaplasma marginale str. St. Maries hypothetical protein YP_153474.1 31186 D 234826 CDS YP_153475.1 56416401 3171732 32410..32967 1 NC_004842.2 conserved family - methyltransferase; hypothetical protein 32967 3171732 AM042 Anaplasma marginale str. St. Maries hypothetical protein YP_153475.1 32410 D 234826 CDS YP_153476.1 56416402 3171052 complement(33143..33541) 1 NC_004842.2 other copies include: AM030, AM065, AM077, AM082 AM210, AM717, AM723, AM989, AM1061, AM1149 and AM1253; member of msp2 superfamily; hypothetical protein 33541 orfX 3171052 orfX Anaplasma marginale str. St. Maries hypothetical protein YP_153476.1 33143 R 234826 CDS YP_153477.1 56416403 3171147 complement(33614..33847) 1 NC_004842.2 other copies include: AM032, AM063, AM721, AM990 AM1059 and AM1251; member of msp2 superfamily; hypothetical protein 33847 orfY 3171147 orfY Anaplasma marginale str. St. Maries hypothetical protein YP_153477.1 33614 R 234826 CDS YP_153478.1 56416404 3171526 complement(36761..38125) 1 NC_004842.2 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 38125 rho 3171526 rho Anaplasma marginale str. St. Maries transcription termination factor Rho YP_153478.1 36761 R 234826 CDS YP_153479.1 56416405 3171838 complement(38234..38851) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00211121.1; hypothetical protein 38851 3171838 AM052 Anaplasma marginale str. St. Maries hypothetical protein YP_153479.1 38234 R 234826 CDS YP_153480.1 56416406 3171303 39269..39469 1 NC_004842.2 COG0291 RpmI ribosomal protein L35; 50S ribosomal protein L35 39469 rpmI 3171303 rpmI Anaplasma marginale str. St. Maries 50S ribosomal protein L35 YP_153480.1 39269 D 234826 CDS YP_153481.1 56416407 3171707 39496..39882 1 NC_004842.2 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit; 50S ribosomal protein L20 39882 rplT 3171707 rplT Anaplasma marginale str. St. Maries 50S ribosomal protein L20 YP_153481.1 39496 D 234826 CDS YP_153482.1 56416408 3171485 39845..40900 1 NC_004842.2 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a heterotetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 1 subfamily; phenylalanyl-tRNA synthetase subunit alpha 40900 pheS 3171485 pheS Anaplasma marginale str. St. Maries phenylalanyl-tRNA synthetase subunit alpha YP_153482.1 39845 D 234826 CDS YP_153483.1 56416409 3170987 40991..41749 1 NC_004842.2 conserved family - dehydrogenase; hypothetical protein 41749 3170987 AM056 Anaplasma marginale str. St. Maries hypothetical protein YP_153483.1 40991 D 234826 CDS YP_153484.1 56416410 3171039 41930..43216 1 NC_004842.2 COG1207 GlmU N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase); UDP-N-acetylglucosamine pyrophosphorylase 43216 glmU 3171039 glmU Anaplasma marginale str. St. Maries UDP-N-acetylglucosamine pyrophosphorylase YP_153484.1 41930 D 234826 CDS YP_153485.1 56416411 3171505 complement(43369..43638) 1 NC_004842.2 binds to lower part of 30S body where it stabilizes two domains; required for efficient assembly of 30S; in Escherichia coli this protein has nuclease activity; 30S ribosomal protein S16 43638 rpsP 3171505 rpsP Anaplasma marginale str. St. Maries 30S ribosomal protein S16 YP_153485.1 43369 R 234826 CDS YP_153486.1 56416412 3171820 43929..45215 1 NC_004842.2 COG0477 ProP permeases of the major facilitator superfamily; similar to NP_359744.1; proline/betaine transport protein 45215 proP1 3171820 proP1 Anaplasma marginale str. St. Maries proline/betaine transport protein YP_153486.1 43929 D 234826 CDS YP_153487.1 56416413 3171639 47834..48067 1 NC_004842.2 other copies include: AM032, AM046, AM721, AM990 AM1059 and AM1251; member of msp2 superfamily; hypothetical protein 48067 orfY 3171639 orfY Anaplasma marginale str. St. Maries hypothetical protein YP_153487.1 47834 D 234826 CDS YP_153488.1 56416414 3171398 48140..48535 1 NC_004842.2 other copies include: AM030, AM044, AM077, AM082 AM210, AM717, AM723, AM989, AM1061, AM1149 and AM1253; member of msp2 superfamily; hypothetical protein 48535 orfX 3171398 orfX Anaplasma marginale str. St. Maries hypothetical protein YP_153488.1 48140 D 234826 CDS YP_153489.1 56416415 3171186 49429..50469 1 NC_004842.2 iron binding protein FbpA precursor 50469 fpbA 3171186 fpbA Anaplasma marginale str. St. Maries iron binding protein FbpA precursor YP_153489.1 49429 D 234826 CDS YP_153490.1 56416416 3171293 50470..50649 1 NC_004842.2 conserved hypothetical protein similar to ZP_00211126.1; hypothetical protein 50649 3171293 AM070 Anaplasma marginale str. St. Maries hypothetical protein YP_153490.1 50470 D 234826 CDS YP_153491.1 56416417 3171170 complement(50899..54888) 1 NC_004842.2 conserved hypothetical protein similar to NP_966764.1; hypothetical protein 54888 3171170 AM071 Anaplasma marginale str. St. Maries hypothetical protein YP_153491.1 50899 R 234826 CDS YP_153492.1 56416418 3171650 55153..61272 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 61272 3171650 AM072 Anaplasma marginale str. St. Maries hypothetical protein YP_153492.1 55153 D 234826 CDS YP_153493.1 56416419 3171580 complement(61443..61898) 1 NC_004842.2 conserved family - transcriptional regulator; NrdR family transcriptional regulator 61898 nrdR 3171580 nrdR Anaplasma marginale str. St. Maries NrdR family transcriptional regulator YP_153493.1 61443 R 234826 CDS YP_153494.1 56416420 3171641 62431..62886 1 NC_004842.2 conserved family - ABC transporter; hypothetical protein 62886 3171641 AM074 Anaplasma marginale str. St. Maries hypothetical protein YP_153494.1 62431 D 234826 CDS YP_153495.1 56416421 3171517 63055..64269 1 NC_004842.2 member of msp2 superfamily; outer membrane protein 14 64269 omp14 3171517 omp14 Anaplasma marginale str. St. Maries outer membrane protein 14 YP_153495.1 63055 D 234826 CDS YP_153496.1 56416422 3171233 complement(64841..65242) 1 NC_004842.2 other copies include: AM030, AM044, AM065, AM082 AM210, AM717, AM723, AM989, AM1061, AM1149 and AM1253; member of msp2 superfamily; hypothetical protein 65242 orfX 3171233 orfX Anaplasma marginale str. St. Maries hypothetical protein YP_153496.1 64841 R 234826 CDS YP_153497.1 56416423 3171162 67571..67978 1 NC_004842.2 other copies include: AM030, AM044, AM065, AM077 AM210, AM717, AM723, AM989, AM1061, AM1149 and AM1253; member of msp2 superfamily; hypothetical protein 67978 orfX 3171162 orfX Anaplasma marginale str. St. Maries hypothetical protein YP_153497.1 67571 D 234826 CDS YP_153498.1 56416424 3171549 68810..69889 1 NC_004842.2 catalyzes the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs; recombinase A 69889 recA 3171549 recA Anaplasma marginale str. St. Maries recombinase A YP_153498.1 68810 D 234826 CDS YP_153499.1 56416425 3171737 69984..70586 1 NC_004842.2 involved in fifth step of pyrimidine biosynthesis; converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate; orotate phosphoribosyltransferase 70586 pyrE 3171737 pyrE Anaplasma marginale str. St. Maries orotate phosphoribosyltransferase YP_153499.1 69984 D 234826 CDS YP_153500.1 56416426 3171205 70620..71426 1 NC_004842.2 COG0476 ThiF dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family; thiamine biosynthesis protein 71426 thiF 3171205 thiF Anaplasma marginale str. St. Maries thiamine biosynthesis protein YP_153500.1 70620 D 234826 CDS YP_153501.1 56416427 3171420 complement(71782..72630) 1 NC_004842.2 similar to AAG34715.1; member of msp2 superfamily; major surface protein 4 72630 msp4 3171420 msp4 Anaplasma marginale str. St. Maries major surface protein 4 YP_153501.1 71782 R 234826 CDS YP_153502.1 56416428 3171198 complement(75388..76326) 1 NC_004842.2 conserved hypothetical protein similar to NP_220824.1; hypothetical protein 76326 3171198 AM092 Anaplasma marginale str. St. Maries hypothetical protein YP_153502.1 75388 R 234826 CDS YP_153503.1 56416429 3171014 complement(76411..76731) 1 NC_004842.2 conserved family - oxidoreductase; hypothetical protein 76731 3171014 AM093 Anaplasma marginale str. St. Maries hypothetical protein YP_153503.1 76411 R 234826 CDS YP_153504.1 56416430 3171848 76781..76984 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 76984 3171848 AM094 Anaplasma marginale str. St. Maries hypothetical protein YP_153504.1 76781 D 234826 CDS YP_153505.1 56416431 3171112 complement(77419..77766) 1 NC_004842.2 COG0526 TrxA thiol-disulfide isomerase and thioredoxins; thioredoxin 77766 trxA 3171112 trxA Anaplasma marginale str. St. Maries thioredoxin YP_153505.1 77419 R 234826 CDS YP_153506.1 56416432 3171574 complement(77775..78587) 1 NC_004842.2 conjugal transfer protein trbG precursor 78587 trbG 3171574 trbG Anaplasma marginale str. St. Maries conjugal transfer protein trbG precursor YP_153506.1 77775 R 234826 CDS YP_153507.1 56416433 3171308 complement(78838..79956) 1 NC_004842.2 pyruvate dehydrogenase E1 component, subunit alpha precursor 79956 pdhA 3171308 pdhA Anaplasma marginale str. St. Maries pyruvate dehydrogenase E1 component, subunit alpha precursor YP_153507.1 78838 R 234826 CDS YP_153508.1 56416434 3171142 complement(79928..80869) 1 NC_004842.2 conserved family - hydrolase; hypothetical protein 80869 rrf 3171142 rrf Anaplasma marginale str. St. Maries hypothetical protein YP_153508.1 79928 R 234826 CDS YP_153509.1 56416435 3171492 complement(84517..85998) 1 NC_004842.2 COG0516 GuaB IMP dehydrogenase/GMP reductase; inosine monophosphate dehydrogenase 85998 guaB 3171492 guaB Anaplasma marginale str. St. Maries inosine monophosphate dehydrogenase YP_153509.1 84517 R 234826 CDS YP_153510.1 56416436 3171001 complement(86056..86820) 1 NC_004842.2 catalyzes the phosphorylation of NAD to NADP; inorganic polyphosphate/ATP-NAD kinase 86820 ppnK 3171001 ppnK Anaplasma marginale str. St. Maries inorganic polyphosphate/ATP-NAD kinase YP_153510.1 86056 R 234826 CDS YP_153511.2 161544994 3171141 complement(86873..87094) 1 NC_004842.2 RpmE; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to L2 and L25 and EF-G; may be near the peptidyltransferase site of the 50S ribosome; 50S ribosomal protein L31 87094 rpmE 3171141 rpmE Anaplasma marginale str. St. Maries 50S ribosomal protein L31 YP_153511.2 86873 R 234826 CDS YP_153512.1 56416438 3171092 87396..88415 1 NC_004842.2 COG0331 FabD (ACP S-malonyltransferase); similar to NP_221088.1; malonyl CoA-ACP transacylase 88415 fabD 3171092 fabD Anaplasma marginale str. St. Maries malonyl CoA-ACP transacylase YP_153512.1 87396 D 234826 CDS YP_153513.1 56416439 3171433 88417..89052 1 NC_004842.2 catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to thymidine monophosphate (dTMP) to form thymidine diphosphate (dTDP); thymidylate kinase 89052 tmk 3171433 tmk Anaplasma marginale str. St. Maries thymidylate kinase YP_153513.1 88417 D 234826 CDS YP_153514.1 56416440 3170952 89107..90375 1 NC_004842.2 conserved family - permease; hypothetical protein 90375 3170952 AM112 Anaplasma marginale str. St. Maries hypothetical protein YP_153514.1 89107 D 234826 CDS YP_153515.1 56416441 3171779 complement(90533..91186) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00211094.1; hypothetical protein 91186 3171779 AM113 Anaplasma marginale str. St. Maries hypothetical protein YP_153515.1 90533 R 234826 CDS YP_153516.1 56416442 3171229 91268..91795 1 NC_004842.2 molecular chaperone that is required for the normal export of envelope proteins out of the cell cytoplasm; in Escherichia coli this proteins forms a homotetramer in the cytoplasm and delivers proteins to be exported to SecA; preprotein translocase subunit SecB 91795 secB 3171229 secB Anaplasma marginale str. St. Maries preprotein translocase subunit SecB YP_153516.1 91268 D 234826 CDS YP_153517.1 56416443 3171240 91749..92567 1 NC_004842.2 conserved hypothetical protein similar to NP_966778.1; hypothetical protein 92567 3171240 AM116 Anaplasma marginale str. St. Maries hypothetical protein YP_153517.1 91749 D 234826 CDS YP_153518.1 56416444 3171938 complement(92821..94131) 1 NC_004842.2 COG0612 PqqL predicted Zn-dependent peptidases; similar to NP_220605.1; mitochondrial processing protease 94131 mpp 3171938 mpp Anaplasma marginale str. St. Maries mitochondrial processing protease YP_153518.1 92821 R 234826 CDS YP_153519.1 56416445 3171115 94178..95500 1 NC_004842.2 conserved family - M23/M37 peptidase domain protein; hypothetical protein 95500 3171115 AM118 Anaplasma marginale str. St. Maries hypothetical protein YP_153519.1 94178 D 234826 CDS YP_153520.1 56416446 3171577 95806..97209 1 NC_004842.2 conserved family - dioxygenase; hypothetical protein 97209 3171577 AM119 Anaplasma marginale str. St. Maries hypothetical protein YP_153520.1 95806 D 234826 CDS YP_153521.1 56416447 3171621 complement(97306..97923) 1 NC_004842.2 catalyzes the formation of riboflavin from 6,7-dimethyl-8-(1-D-ribityl)lumazine; riboflavin synthase subunit alpha 97923 ribA 3171621 ribA Anaplasma marginale str. St. Maries riboflavin synthase subunit alpha YP_153521.1 97306 R 234826 CDS YP_153522.1 56416448 3171586 97418..98149 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 98149 3171586 AM122 Anaplasma marginale str. St. Maries hypothetical protein YP_153522.1 97418 D 234826 CDS YP_153523.1 56416449 3171775 complement(98205..100475) 1 NC_004842.2 member of msp1b gene family, full length gene 2 other copy is AM180; member of msp1 superfamily; major surface protein 1B-2 100475 msp1B-2 3171775 msp1B-2 Anaplasma marginale str. St. Maries major surface protein 1B-2 YP_153523.1 98205 R 234826 CDS YP_153524.1 56416450 3171612 complement(100706..101902) 1 NC_004842.2 member of msp1b gene family, partial gene 2; member of msp1 superfamily; major surface protein 1B 101902 msp1bpg2 3171612 msp1bpg2 Anaplasma marginale str. St. Maries major surface protein 1B YP_153524.1 100706 R 234826 CDS YP_153525.1 56416451 3171275 complement(101880..105338) 1 NC_004842.2 COG1197 Mfd transcription-repair coupling factor - superfamily II helicase; transcription repair coupling factor 105338 mfd 3171275 mfd Anaplasma marginale str. St. Maries transcription repair coupling factor YP_153525.1 101880 R 234826 CDS YP_153526.1 56416452 3171655 105394..105909 1 NC_004842.2 COG0328 RnhA ribonuclease HI; similar to NP_767956.1; ribonuclease H 105909 rnhA 3171655 rnhA Anaplasma marginale str. St. Maries ribonuclease H YP_153526.1 105394 D 234826 CDS YP_153527.1 56416453 3171296 105919..108918 1 NC_004842.2 conserved hypothetical protein similar to ZP_00211075.1; hypothetical protein 108918 3171296 AM127 Anaplasma marginale str. St. Maries hypothetical protein YP_153527.1 105919 D 234826 CDS YP_153528.1 56416454 3171801 109082..109843 1 NC_004842.2 Catalyzes the phosphorylation of UMP to UDP; uridylate kinase 109843 pyrH 3171801 pyrH Anaplasma marginale str. St. Maries uridylate kinase YP_153528.1 109082 D 234826 CDS YP_153529.1 56416455 3171583 109852..110403 1 NC_004842.2 Rrf; Frr; ribosome-recycling factor; release factor 4; RF4; recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G; A GTPase-dependent process results in release of 50S from 70S; inhibited by release factor RF-1; essential for viability; structurally similar to tRNAs; ribosome recycling factor 110403 frr 3171583 frr Anaplasma marginale str. St. Maries ribosome recycling factor YP_153529.1 109852 D 234826 CDS YP_153530.1 56416456 3171217 110416..111114 1 NC_004842.2 COG0020 UppS undecaprenyl pyrophosphate synthase; undecaprenyl diphosphate synthase 111114 uppS 3171217 uppS Anaplasma marginale str. St. Maries undecaprenyl diphosphate synthase YP_153530.1 110416 D 234826 CDS YP_153531.1 56416457 3171095 111068..111952 1 NC_004842.2 COG0575 CdsA CDP-diglyceride synthetase; phosphatidate cytidylyltransferase 111952 cdsA 3171095 cdsA Anaplasma marginale str. St. Maries phosphatidate cytidylyltransferase YP_153531.1 111068 D 234826 CDS YP_153532.1 56416458 3170980 complement(112247..114160) 1 NC_004842.2 member of msp1b gene family, partial gene 3; member of msp1 superfamily; major surface protein 1B 114160 msp1Bpg3 3170980 msp1Bpg3 Anaplasma marginale str. St. Maries major surface protein 1B YP_153532.1 112247 R 234826 CDS YP_153533.1 56416459 3171478 complement(114304..117225) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 117225 3171478 AM136 Anaplasma marginale str. St. Maries hypothetical protein YP_153533.1 114304 R 234826 CDS YP_153534.1 56416460 3170977 complement(117369..118097) 1 NC_004842.2 COG0152 PurC phosphoribosylaminoimidazole-succinocarboxamide (SAICAR); phosphoribosylaminoimidazole-succinocarboxamide synthase 118097 purC 3170977 purC Anaplasma marginale str. St. Maries phosphoribosylaminoimidazole-succinocarboxamide synthase YP_153534.1 117369 R 234826 CDS YP_153535.1 56416461 3171099 118215..119507 1 NC_004842.2 catalyzes a two-step reaction, first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class II aminoacyl-tRNA synthetase; forms homodimers; some organisms have a paralogous gene, hisZ, that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG; histidyl-tRNA synthetase 119507 hisS 3171099 hisS Anaplasma marginale str. St. Maries histidyl-tRNA synthetase YP_153535.1 118215 D 234826 CDS YP_153536.1 56416462 3171585 complement(119517..120272) 1 NC_004842.2 conserved family - disulfide oxidoreductase; hypothetical protein 120272 3171585 AM139 Anaplasma marginale str. St. Maries hypothetical protein YP_153536.1 119517 R 234826 CDS YP_153537.1 56416463 3170971 120631..121656 1 NC_004842.2 COG3175 COX11 cytochrome oxidase assembly factor; cytochrome C oxidase assembly protein 121656 coxW 3170971 coxW Anaplasma marginale str. St. Maries cytochrome C oxidase assembly protein YP_153537.1 120631 D 234826 CDS YP_153538.1 56416464 3171037 121691..122524 1 NC_004842.2 catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5,10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate; 3-methyl-2-oxobutanoate hydroxymethyltransferase 122524 panB 3171037 panB Anaplasma marginale str. St. Maries 3-methyl-2-oxobutanoate hydroxymethyltransferase YP_153538.1 121691 D 234826 CDS YP_153539.1 56416465 3171443 complement(122666..123292) 1 NC_004842.2 ATP-binding protein; required for proper cytochrome C maturation; cytochrome C biogenesis protein CcmA 123292 ccmA 3171443 ccmA Anaplasma marginale str. St. Maries cytochrome C biogenesis protein CcmA YP_153539.1 122666 R 234826 CDS YP_153540.1 56416466 3171180 complement(123325..124611) 1 NC_004842.2 adds enolpyruvyl to UDP-N-acetylglucosamine as a component of cell wall formation; gram-positive bacteria have 2 copies of MurA which are active; UDP-N-acetylglucosamine 1-carboxyvinyltransferase 124611 murA 3171180 murA Anaplasma marginale str. St. Maries UDP-N-acetylglucosamine 1-carboxyvinyltransferase YP_153540.1 123325 R 234826 CDS YP_153541.1 56416467 3171480 complement(124613..125170) 1 NC_004842.2 Catalyzes the formation of dUTP from dCTP in thymidylate biosynthesis; deoxycytidine triphosphate deaminase 125170 dcd 3171480 dcd Anaplasma marginale str. St. Maries deoxycytidine triphosphate deaminase YP_153541.1 124613 R 234826 CDS YP_153542.1 56416468 3171007 complement(125269..126114) 1 NC_004842.2 conserved hypothetical protein similar to NP_966731.1; hypothetical protein 126114 3171007 AM148 Anaplasma marginale str. St. Maries hypothetical protein YP_153542.1 125269 R 234826 CDS YP_153543.1 56416469 3171825 126498..126776 1 NC_004842.2 COG1278 CspC cold shock proteins; cold shock protein 126776 cspA 3171825 cspA Anaplasma marginale str. St. Maries cold shock protein YP_153543.1 126498 D 234826 CDS YP_153544.1 56416470 3171243 126818..128905 1 NC_004842.2 COG0347 GlnK nitrogen regulatory protein PII; similar to NP_420550.1; nitrogen regulation protein 128905 ntrY 3171243 ntrY Anaplasma marginale str. St. Maries nitrogen regulation protein YP_153544.1 126818 D 234826 CDS YP_153545.1 56416471 3171717 128874..130079 1 NC_004842.2 COG0349 Rnd ribonuclease D; similar to NP_531848.1; other copies include: AM1015; ribonuclease D 130079 rnd 3171717 rnd Anaplasma marginale str. St. Maries ribonuclease D YP_153545.1 128874 D 234826 CDS YP_153546.1 56416472 3171105 complement(130162..132183) 1 NC_004842.2 COG0272 Lig NAD-dependent DNA ligase; DNA ligase 132183 ligA 3171105 ligA Anaplasma marginale str. St. Maries DNA ligase YP_153546.1 130162 R 234826 CDS YP_153547.1 56416473 3171450 complement(132192..132524) 1 NC_004842.2 similar to NP_772351.1; glutaredoxin-like protein GRLA 132524 grxC2 3171450 grxC2 Anaplasma marginale str. St. Maries glutaredoxin-like protein GRLA YP_153547.1 132192 R 234826 CDS YP_153548.1 56416474 3171729 complement(132514..132750) 1 NC_004842.2 conserved hypothetical protein similar to NP_966273.1; hypothetical protein 132750 3171729 AM154 Anaplasma marginale str. St. Maries hypothetical protein YP_153548.1 132514 R 234826 CDS YP_153549.1 56416475 3171607 complement(132894..133445) 1 NC_004842.2 conserved family - thioredoxin; hypothetical protein 133445 3171607 AM156 Anaplasma marginale str. St. Maries hypothetical protein YP_153549.1 132894 R 234826 CDS YP_153550.1 56416476 3171497 complement(133393..134763) 1 NC_004842.2 Sms; stabilizes the strand-invasion intermediate during the DNA repair; involved in recombination of donor DNA and plays an important role in DNA damage repair after exposure to mutagenic agents; DNA repair protein RadA 134763 radA 3171497 radA Anaplasma marginale str. St. Maries DNA repair protein RadA YP_153550.1 133393 R 234826 CDS YP_153551.1 56416477 3171431 135010..137652 1 NC_004842.2 conserved family - TRAP-type uncharacterized transport system, fused permease; hypothetical protein 137652 3171431 AM159 Anaplasma marginale str. St. Maries hypothetical protein YP_153551.1 135010 D 234826 CDS YP_153552.1 56416478 3171236 137659..138246 1 NC_004842.2 conserved family - uncharacterized membrane protein, required for colicin V production; hypothetical protein 138246 3171236 AM160 Anaplasma marginale str. St. Maries hypothetical protein YP_153552.1 137659 D 234826 CDS YP_153553.1 56416479 3171189 138257..138640 1 NC_004842.2 binds cooperatively with S18 to the S15-16S complex, allowing platform assembly to continue with S11 and S21; 30S ribosomal protein S6 138640 rpsF 3171189 rpsF Anaplasma marginale str. St. Maries 30S ribosomal protein S6 YP_153553.1 138257 D 234826 CDS YP_153554.1 56416480 3171184 138716..138943 1 NC_004842.2 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA; helps stabilize the platform of the 30S subunit; 30S ribosomal protein S18 138943 rpsR 3171184 rpsR Anaplasma marginale str. St. Maries 30S ribosomal protein S18 YP_153554.1 138716 D 234826 CDS YP_153555.1 56416481 3171524 138963..139625 1 NC_004842.2 in Escherichia coli this protein is wrapped around the base of the L1 stalk; 50S ribosomal protein L9 139625 rplI 3171524 rplI Anaplasma marginale str. St. Maries 50S ribosomal protein L9 YP_153555.1 138963 D 234826 CDS YP_153556.1 56416482 3171408 139651..140943 1 NC_004842.2 catalyzes the reaction of glycine with 5,10-methylenetetrahydrofolate to form L-serine and tetrahydrofolate; serine hydroxymethyltransferase 140943 glyA 3171408 glyA Anaplasma marginale str. St. Maries serine hydroxymethyltransferase YP_153556.1 139651 D 234826 CDS YP_153557.1 56416483 3171892 141074..141415 1 NC_004842.2 conserved family - CyaY protein; hypothetical protein 141415 3171892 AM166 Anaplasma marginale str. St. Maries hypothetical protein YP_153557.1 141074 D 234826 CDS YP_153558.1 56416484 3171700 141396..143144 1 NC_004842.2 COG1132 MdlB ABC-type multidrug/protein/lipid transport system, ATPase component; ABC transporter 143144 msbA2 3171700 msbA2 Anaplasma marginale str. St. Maries ABC transporter YP_153558.1 141396 D 234826 CDS YP_153559.1 56416485 3171669 143415..145214 1 NC_004842.2 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; succinate dehydrogenase flavoprotein subunit 145214 sdhA 3171669 sdhA Anaplasma marginale str. St. Maries succinate dehydrogenase flavoprotein subunit YP_153559.1 143415 D 234826 CDS YP_153560.1 56416486 3171556 145239..146027 1 NC_004842.2 part of four member succinate dehydrogenase enzyme complex that forms a trimeric complex (trimer of tetramers); SdhA/B are the catalytic subcomplex and can exhibit succinate dehydrogenase activity in the absence of SdhC/D which are the membrane components and form cytochrome b556; SdhC binds ubiquinone; oxidizes succinate to fumarate while reducing ubiquinone to ubiquinol; the catalytic subunits are similar to fumarate reductase; succinate dehydrogenase iron-sulfur subunit 146027 sdhB 3171556 sdhB Anaplasma marginale str. St. Maries succinate dehydrogenase iron-sulfur subunit YP_153560.1 145239 D 234826 CDS YP_153561.1 56416487 3171755 146028..146903 1 NC_004842.2 flavin dependent thymidylate synthase; ThyX; thymidylate synthase complementing protein; catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate; the enzyme from Mycobacterium tuberculosis forms homotetramers; uses FAD as a cofactor; FAD-dependent thymidylate synthase 146903 thyX 3171755 thyX Anaplasma marginale str. St. Maries FAD-dependent thymidylate synthase YP_153561.1 146028 D 234826 CDS YP_153562.1 56416488 3171101 147040..148221 1 NC_004842.2 bicyclomycin resistance protein; similar to NP_416687.1; bicyclomycin resistance protein 148221 bcr2 3171101 bcr2 Anaplasma marginale str. St. Maries bicyclomycin resistance protein YP_153562.1 147040 D 234826 CDS YP_153563.1 56416489 3171768 complement(148363..149358) 1 NC_004842.2 promotes strand exchange during homologous recombination; RuvAB complex promotes branch migration; RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences; forms hexameric rings around opposite DNA arms; requires ATP for branch migration and orientation of RuvAB complex determines direction of migration; Holliday junction DNA helicase RuvB 149358 ruvB 3171768 ruvB Anaplasma marginale str. St. Maries Holliday junction DNA helicase RuvB YP_153563.1 148363 R 234826 CDS YP_153564.1 56416490 3171168 complement(149355..149927) 1 NC_004842.2 plays an essential role in ATP-dependent branch migration of the Holliday junction; Holliday junction DNA helicase RuvA 149927 ruvA 3171168 ruvA Anaplasma marginale str. St. Maries Holliday junction DNA helicase RuvA YP_153564.1 149355 R 234826 CDS YP_153565.1 56416491 3171705 complement(149924..150676) 1 NC_004842.2 COG0755 CcmC ABC-type transport system involved in cytochrome C biogenesis, permease component; heme exporter protein C 150676 ccmc 3171705 ccmc Anaplasma marginale str. St. Maries heme exporter protein C YP_153565.1 149924 R 234826 CDS YP_153566.1 56416492 3171656 150861..151595 1 NC_004842.2 COG0194 Gmk guanylate kinase; guanylate kinase 151595 gmk 3171656 gmk Anaplasma marginale str. St. Maries guanylate kinase YP_153566.1 150861 D 234826 CDS YP_153567.1 56416493 3171210 151721..152833 1 NC_004842.2 conserved hypothetical protein similar to NP_630160.1; hypothetical protein 152833 3171210 AM178 Anaplasma marginale str. St. Maries hypothetical protein YP_153567.1 151721 D 234826 CDS YP_153568.1 56416494 3171662 152987..153886 1 NC_004842.2 COG0190 FolD 5,10-methylene-tetrahydrofolate dehydrogenase/methenyl tetrahydrofolate cyclohydrolase; methylenetetrahydrofolate dehydrogenase 153886 folD 3171662 folD Anaplasma marginale str. St. Maries methylenetetrahydrofolate dehydrogenase YP_153568.1 152987 D 234826 CDS YP_153569.1 56416495 3171380 154357..156576 1 NC_004842.2 member of msp1b gene family, full length gene 1 other copy is AM123; member of msp1 superfamily; major surface protein 1B-1 156576 msp1B-1 3171380 msp1B-1 Anaplasma marginale str. St. Maries major surface protein 1B-1 YP_153569.1 154357 D 234826 CDS YP_153570.1 56416496 3171918 157060..159456 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 159456 3171918 AM185 Anaplasma marginale str. St. Maries hypothetical protein YP_153570.1 157060 D 234826 CDS YP_153571.1 56416497 3171928 complement(159495..159944) 1 NC_004842.2 member of msp1b gene family, partial gene 1; member of msp1 superfamily; similar to AAD20331.1; major surface protein 1B 159944 msp1Bpg1 3171928 msp1Bpg1 Anaplasma marginale str. St. Maries major surface protein 1B YP_153571.1 159495 R 234826 CDS YP_153572.1 56416498 3171195 complement(160185..160817) 1 NC_004842.2 conserved family - hydrolase or acyltransferase; hypothetical protein 160817 3171195 AM189 Anaplasma marginale str. St. Maries hypothetical protein YP_153572.1 160185 R 234826 CDS YP_153573.1 56416499 3171724 complement(161059..161598) 1 NC_004842.2 COG3303 NrfA formate-dependent nitrite reductase, periplasmic cytochrome C552 subunit; cytochrome C 161598 cycM 3171724 cycM Anaplasma marginale str. St. Maries cytochrome C YP_153573.1 161059 R 234826 CDS YP_153574.1 56416500 3171318 complement(161998..163518) 1 NC_004842.2 COG1009 NuoL NADH:ubiquinone oxidoreductase subunit 5 (chain L)/multisubunit Na+/H+ antiporter, MnhA; similar to NP_220667.1; NADH dehydrogenase I subunit L 163518 nuoL2 3171318 nuoL2 Anaplasma marginale str. St. Maries NADH dehydrogenase I subunit L YP_153574.1 161998 R 234826 CDS YP_153575.1 56416501 3171387 complement(163888..166542) 1 NC_004842.2 catalyzes the formation of phosphoenolpyruvate from pyruvate; pyruvate phosphate dikinase 166542 ppdK 3171387 ppdK Anaplasma marginale str. St. Maries pyruvate phosphate dikinase YP_153575.1 163888 R 234826 CDS YP_153576.1 56416502 3171508 complement(166838..167347) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 167347 3171508 AM197 Anaplasma marginale str. St. Maries hypothetical protein YP_153576.1 166838 R 234826 CDS YP_153577.1 56416503 3171744 complement(167350..167973) 1 NC_004842.2 conserved family - phosphatase; hypothetical protein 167973 3171744 AM198 Anaplasma marginale str. St. Maries hypothetical protein YP_153577.1 167350 R 234826 CDS YP_153578.1 56416504 3171337 complement(168165..169142) 1 NC_004842.2 COG0173 AspS aspartyl-tRNA synthetase; open reading frame split domain with AM200; asparaginyl-tRNA synthetase 169142 aspS 3171337 aspS Anaplasma marginale str. St. Maries asparaginyl-tRNA synthetase YP_153578.1 168165 R 234826 CDS YP_153579.1 56416505 3171557 complement(169054..169944) 1 NC_004842.2 COG0173 AspS aspartyl-tRNA synthetase; open reading frame split domain with AM199; asparaginyl-tRNA synthetase 169944 aspS 3171557 aspS Anaplasma marginale str. St. Maries asparaginyl-tRNA synthetase YP_153579.1 169054 R 234826 CDS YP_153580.1 56416506 3171626 170363..170950 1 NC_004842.2 conserved hypothetical protein similar to NP_360175.1; hypothetical protein 170950 3171626 AM202 Anaplasma marginale str. St. Maries hypothetical protein YP_153580.1 170363 D 234826 CDS YP_153581.1 56416507 3171246 170965..171891 1 NC_004842.2 catalyzes the second step in the glutathione biosynthesis pathway, where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine = ADP + phosphate + glutathione; glutathione synthetase 171891 gshB 3171246 gshB Anaplasma marginale str. St. Maries glutathione synthetase YP_153581.1 170965 D 234826 CDS YP_153582.1 56416508 3171882 172027..173031 1 NC_004842.2 D-alanine--D-alanine ligase; DdlA; DdlB; cytoplasmic; catalyzes the formation of D-alanyl-D-alanine from two D-alanines in peptidoglycan synthesis; there are two forms of this enzyme in Escherichia coli; D-alanine--D-alanine ligase 173031 ddl 3171882 ddl Anaplasma marginale str. St. Maries D-alanine--D-alanine ligase YP_153582.1 172027 D 234826 CDS YP_153583.1 56416509 3170970 173024..173797 1 NC_004842.2 COG1589 FtsQ cell division septal protein; cell division protein 173797 ftsQ 3170970 ftsQ Anaplasma marginale str. St. Maries cell division protein YP_153583.1 173024 D 234826 CDS YP_153584.1 56416510 3171290 174038..175438 1 NC_004842.2 COG3852 NtrB signal transduction histidine kinase, nitrogen specific; similar to AAL08835.1; nitrogen assimilation regulatory protein 175438 ntrX 3171290 ntrX Anaplasma marginale str. St. Maries nitrogen assimilation regulatory protein YP_153584.1 174038 D 234826 CDS YP_153585.1 56416511 3171183 175825..176214 1 NC_004842.2 other copies include: AM030, AM044, AM065, AM077 AM082, AM717, AM723, AM989, AM1061, AM1149 and AM1253; member of msp2 superfamily; hypothetical protein 176214 orfX 3171183 orfX Anaplasma marginale str. St. Maries hypothetical protein YP_153585.1 175825 D 234826 CDS YP_153586.1 56416512 3171874 complement(177599..179011) 1 NC_004842.2 COG1249 Lpd dihydrolipoamide dehydrogenase/glutathione oxidoreductase; similar to EAA26057.1; glutathione reductase 179011 gor 3171874 gor Anaplasma marginale str. St. Maries glutathione reductase YP_153586.1 177599 R 234826 CDS YP_153587.1 56416513 3171542 179210..181738 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 181738 3171542 AM216 Anaplasma marginale str. St. Maries hypothetical protein YP_153587.1 179210 D 234826 CDS YP_153588.1 56416514 3171334 181807..183273 1 NC_004842.2 conserved hypothetical protein similar to NP_966526.1; hypothetical protein 183273 3171334 AM217 Anaplasma marginale str. St. Maries hypothetical protein YP_153588.1 181807 D 234826 CDS YP_153589.1 56416515 3171169 183273..183896 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210423.1; hypothetical protein 183896 3171169 AM218 Anaplasma marginale str. St. Maries hypothetical protein YP_153589.1 183273 D 234826 CDS YP_153590.1 56416516 3171783 183893..184429 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210422.1; hypothetical protein 184429 3171783 AM219 Anaplasma marginale str. St. Maries hypothetical protein YP_153590.1 183893 D 234826 CDS YP_153591.1 56416517 3171509 184598..185461 1 NC_004842.2 conserved family - metal-dependent hydrolase; hypothetical protein 185461 3171509 AM220 Anaplasma marginale str. St. Maries hypothetical protein YP_153591.1 184598 D 234826 CDS YP_153592.1 56416518 3171110 complement(185456..186283) 1 NC_004842.2 COG0174 GlnA glutamine synthase; other copies include: AM1206; glutamine synthetase 186283 glnA 3171110 glnA Anaplasma marginale str. St. Maries glutamine synthetase YP_153592.1 185456 R 234826 CDS YP_153593.1 56416519 3170945 complement(186261..187388) 1 NC_004842.2 COG0573 PstC ABC-type phosphate transport system, permease component; similar to NP_531125.1; phosphate ABC transporter permease 187388 pstC 3170945 pstC Anaplasma marginale str. St. Maries phosphate ABC transporter permease YP_153593.1 186261 R 234826 CDS YP_153594.1 56416520 3171157 187473..190121 1 NC_004842.2 Catalyzes a two-step reaction, first charging an alanyl molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; alanyl-tRNA synthetase 190121 alaS 3171157 alaS Anaplasma marginale str. St. Maries alanyl-tRNA synthetase YP_153594.1 187473 D 234826 CDS YP_153595.1 56416521 3171312 complement(190828..191712) 1 NC_004842.2 COG0074 SucD succinyl-CoA synthetase subunit alpha; similar to EAA25376.1; succinyl-CoA ligase subunit alpha 191712 sucD 3171312 sucD Anaplasma marginale str. St. Maries succinyl-CoA ligase subunit alpha YP_153595.1 190828 R 234826 CDS YP_153596.1 56416522 3171455 complement(191721..192887) 1 NC_004842.2 catalyzes the interconversion of succinyl-CoA and succinate; succinyl-CoA synthetase subunit beta 192887 sucC 3171455 sucC Anaplasma marginale str. St. Maries succinyl-CoA synthetase subunit beta YP_153596.1 191721 R 234826 CDS YP_153597.2 161544993 3171375 complement(192990..193253) 1 NC_004842.2 a small basic protein that is one of the last in the subunit assembly; omission does not prevent assembly but the subunit is inactive; binds central domain of 16S rRNA; 30S ribosomal protein S21 193253 rpsU 3171375 rpsU Anaplasma marginale str. St. Maries 30S ribosomal protein S21 YP_153597.2 192990 R 234826 CDS YP_153598.1 56416524 3171087 complement(193361..194377) 1 NC_004842.2 COG0226 ABC-type phosphate transport system periplasmic component; phosphate ABC transporter substrate-binding protein 194377 pstS 3171087 pstS Anaplasma marginale str. St. Maries phosphate ABC transporter substrate-binding protein YP_153598.1 193361 R 234826 CDS YP_153599.1 56416525 3171292 complement(194437..195069) 1 NC_004842.2 similar to AAB02878.1; major surface protein 5 195069 msp5 3171292 msp5 Anaplasma marginale str. St. Maries major surface protein 5 YP_153599.1 194437 R 234826 CDS YP_153600.1 56416526 3171868 complement(195252..196268) 1 NC_004842.2 conserved family - 2-nitropropane dioxygenase; hypothetical protein 196268 3171868 AM237 Anaplasma marginale str. St. Maries hypothetical protein YP_153600.1 195252 R 234826 CDS YP_153601.1 56416527 3171464 complement(196271..196813) 1 NC_004842.2 COG3038 CybB cytochrome B561; similar to ZP_00011855.1; cytochrome b561 196813 cybB 3171464 cybB Anaplasma marginale str. St. Maries cytochrome b561 YP_153601.1 196271 R 234826 CDS YP_153602.1 56416528 3171547 197126..198754 1 NC_004842.2 conserved family - ABC transporter permease protein; hypothetical protein 198754 3171547 AM240 Anaplasma marginale str. St. Maries hypothetical protein YP_153602.1 197126 D 234826 CDS YP_153603.1 56416529 3171917 complement(198949..200487) 1 NC_004842.2 COG1404 aprE subtilisin-like serine proteases; similar to EAA25533.1; alkaline protease secretion protein 200487 aprE 3171917 aprE Anaplasma marginale str. St. Maries alkaline protease secretion protein YP_153603.1 198949 R 234826 CDS YP_153604.1 56416530 3171145 complement(200575..201231) 1 NC_004842.2 conserved hypothetical protein similar to NP_966600.1; hypothetical protein 201231 3171145 AM242 Anaplasma marginale str. St. Maries hypothetical protein YP_153604.1 200575 R 234826 CDS YP_153605.1 56416531 3171617 201697..203013 1 NC_004842.2 COG0771 MurD UDP-N-acetylmuramoylalanine-D-glutamate ligase; UDP-N-acetylmuramoylalanine--D-glutamate ligase 203013 murD 3171617 murD Anaplasma marginale str. St. Maries UDP-N-acetylmuramoylalanine--D-glutamate ligase YP_153605.1 201697 D 234826 CDS YP_153606.1 56416532 3171160 complement(203038..204363) 1 NC_004842.2 forms dimers; may be involved in cell envelope integrity; interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA; translocation protein TolB 204363 tolB 3171160 tolB Anaplasma marginale str. St. Maries translocation protein TolB YP_153606.1 203038 R 234826 CDS YP_153607.1 56416533 3171510 complement(204370..205998) 1 NC_004842.2 conserved family - metallo-beta-lactamase; hypothetical protein 205998 3171510 AM245 Anaplasma marginale str. St. Maries hypothetical protein YP_153607.1 204370 R 234826 CDS YP_153608.1 56416534 3171390 206240..206812 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 206812 3171390 AM247 Anaplasma marginale str. St. Maries hypothetical protein YP_153608.1 206240 D 234826 CDS YP_153609.1 56416535 3171504 206845..208338 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210406.1; hypothetical protein 208338 3171504 AM248 Anaplasma marginale str. St. Maries hypothetical protein YP_153609.1 206845 D 234826 CDS YP_153610.1 56416536 3171629 208523..208897 1 NC_004842.2 interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone; located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side; mutations in the S12 gene confer streptomycin resistance; 30S ribosomal protein S12 208897 rpsL 3171629 rpsL Anaplasma marginale str. St. Maries 30S ribosomal protein S12 YP_153610.1 208523 D 234826 CDS YP_153611.1 56416537 3171302 208915..209397 1 NC_004842.2 binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit; 30S ribosomal protein S7 209397 rpsG 3171302 rpsG Anaplasma marginale str. St. Maries 30S ribosomal protein S7 YP_153611.1 208915 D 234826 CDS YP_153612.1 56416538 3171791 209431..211503 1 NC_004842.2 EF-G; promotes GTP-dependent translocation of the ribosome during translation; many organisms have multiple copies of this gene; elongation factor G 211503 fusA 3171791 fusA Anaplasma marginale str. St. Maries elongation factor G YP_153612.1 209431 D 234826 CDS YP_153613.1 56416539 3170990 211515..212696 1 NC_004842.2 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 212696 tuf 3170990 tuf Anaplasma marginale str. St. Maries elongation factor Tu YP_153613.1 211515 D 234826 CDS YP_153614.1 56416540 3171545 212796..213008 1 NC_004842.2 forms a complex with SecY and SecG; SecYEG forms a protein-conducting channel to which secA binds and translocates targeted polypeptides across the cytoplasmic membrane, a process driven by ATP and a proton-motive force; preprotein translocase subunit SecE 213008 secE 3171545 secE Anaplasma marginale str. St. Maries preprotein translocase subunit SecE YP_153614.1 212796 D 234826 CDS YP_153615.1 56416541 3171068 212992..213558 1 NC_004842.2 COG0250 NusG transcription antiterminator; transcription antitermination protein 213558 nusG 3171068 nusG Anaplasma marginale str. St. Maries transcription antitermination protein YP_153615.1 212992 D 234826 CDS YP_153616.1 56416542 3171370 213562..214005 1 NC_004842.2 binds directly to 23S ribosomal RNA; 50S ribosomal protein L11 214005 rplK 3171370 rplK Anaplasma marginale str. St. Maries 50S ribosomal protein L11 YP_153616.1 213562 D 234826 CDS YP_153617.2 161544992 3171013 214002..214676 1 NC_004842.2 in Escherichia coli and Methanococcus, this protein autoregulates expression; the binding site in the mRNA mimics the binding site in the 23S rRNA; 50S ribosomal protein L1 214676 rplA 3171013 rplA Anaplasma marginale str. St. Maries 50S ribosomal protein L1 YP_153617.2 214002 D 234826 CDS YP_153618.1 56416544 3171560 214712..215203 1 NC_004842.2 binds the two ribosomal protein L7/L12 dimers and anchors them to the large ribosomal subunit; 50S ribosomal protein L10 215203 rplJ 3171560 rplJ Anaplasma marginale str. St. Maries 50S ribosomal protein L10 YP_153618.1 214712 D 234826 CDS YP_153619.1 56416545 3171055 215328..215732 1 NC_004842.2 present in two forms; L12 is normal, while L7 is aminoacylated at the N-terminal serine; the only multicopy ribosomal protein; 4:1 ratio of L7/L12 per ribosome; two L12 dimers bind L10; critically important for translation efficiency and fidelity; stimulates GTPase activity of translation factors; 50S ribosomal protein L7/L12 215732 rplL 3171055 rplL Anaplasma marginale str. St. Maries 50S ribosomal protein L7/L12 YP_153619.1 215328 D 234826 CDS YP_153620.1 56416546 3171249 215769..219917 1 NC_004842.2 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates; beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme; DNA-directed RNA polymerase subunit beta 219917 rpoB 3171249 rpoB Anaplasma marginale str. St. Maries DNA-directed RNA polymerase subunit beta YP_153620.1 215769 D 234826 CDS YP_153621.1 56416547 3171291 219929..224176 1 NC_004842.2 COG0086 RpoC DNA-directed RNA polymerase beta subunit/160 kD subunit; DNA-directed RNA polymerase subunit beta' 224176 rpoC 3171291 rpoC Anaplasma marginale str. St. Maries DNA-directed RNA polymerase subunit beta' YP_153621.1 219929 D 234826 CDS YP_153622.1 56416548 3171377 complement(224173..225192) 1 NC_004842.2 COG0164 RnhB ribonuclease HII; ribonuclease HII 225192 rnhB 3171377 rnhB Anaplasma marginale str. St. Maries ribonuclease HII YP_153622.1 224173 R 234826 CDS YP_153623.1 56416549 3171618 225409..228828 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 228828 3171618 AM265 Anaplasma marginale str. St. Maries hypothetical protein YP_153623.1 225409 D 234826 CDS YP_153624.1 56416550 3171447 complement(229023..229526) 1 NC_004842.2 conserved hypothetical protein similar to NP_965966.1; hypothetical protein 229526 3171447 AM266 Anaplasma marginale str. St. Maries hypothetical protein YP_153624.1 229023 R 234826 CDS YP_153625.1 56416551 3171093 complement(229773..230915) 1 NC_004842.2 conserved family - 7-keto-8-aminopelargonate synthetase; hypothetical protein 230915 3171093 AM268 Anaplasma marginale str. St. Maries hypothetical protein YP_153625.1 229773 R 234826 CDS YP_153626.1 56416552 3171097 231322..231849 1 NC_004842.2 conserved family - Na+/H+ antiporter; hypothetical protein 231849 3171097 AM270 Anaplasma marginale str. St. Maries hypothetical protein YP_153626.1 231322 D 234826 CDS YP_153627.1 56416553 3171774 complement(231937..232710) 1 NC_004842.2 type III; catalyzes the formation of (R)-4'-phosphopantothenate from (R)-pantothenate in coenzyme A biosynthesis; type III pantothenate kinases are not subject to feedback inhibition from coenzyme A and have a high Km for ATP; pantothenate kinase 232710 3171774 AM271 Anaplasma marginale str. St. Maries pantothenate kinase YP_153627.1 231937 R 234826 CDS YP_153628.1 56416554 3171809 complement(232717..233886) 1 NC_004842.2 catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway; uses a flavin nucleotide as an essential cofactor; class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus, which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors; dihydroorotate dehydrogenase 2 233886 pyrD 3171809 pyrD Anaplasma marginale str. St. Maries dihydroorotate dehydrogenase 2 YP_153628.1 232717 R 234826 CDS YP_153629.1 56416555 3171511 234047..234637 1 NC_004842.2 conserved family - N-formylmethionyl-tRNA deformylase; hypothetical protein 234637 3171511 AM275 Anaplasma marginale str. St. Maries hypothetical protein YP_153629.1 234047 D 234826 CDS YP_153630.1 56416556 3171231 234769..235521 1 NC_004842.2 conserved family -; hypothetical protein 235521 3171231 AM276 Anaplasma marginale str. St. Maries hypothetical protein YP_153630.1 234769 D 234826 CDS YP_153631.1 56416557 3171552 235885..236751 1 NC_004842.2 conserved hypothetical protein similar to ZP_00073278.1; hypothetical protein 236751 3171552 AM279 Anaplasma marginale str. St. Maries hypothetical protein YP_153631.1 235885 D 234826 CDS YP_153632.1 56416558 3171784 236889..237488 1 NC_004842.2 COG0259 PdxH pyridoxamine phosphate oxidase; pyridoxamine 5-phosphate oxidase 237488 pdxH 3171784 pdxH Anaplasma marginale str. St. Maries pyridoxamine 5-phosphate oxidase YP_153632.1 236889 D 234826 CDS YP_153633.1 56416559 3171129 complement(237493..238911) 1 NC_004842.2 COG0769 MurE UDP-N-acetylmuramyl tripeptide synthase; UDP-N-acetylmuramoylalanyl-D-glutamate 2,6-diaminopimelate ligase 238911 murE 3171129 murE Anaplasma marginale str. St. Maries UDP-N-acetylmuramoylalanyl-D-glutamate 2,6-diaminopimelate ligase YP_153633.1 237493 R 234826 CDS YP_153634.1 56416560 3171146 238895..239110 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 239110 3171146 AM283 Anaplasma marginale str. St. Maries hypothetical protein YP_153634.1 238895 D 234826 CDS YP_153635.1 56416561 3171537 complement(239132..240358) 1 NC_004842.2 COG0626 cystathionine beta-lyases/cystathionine gamma-synthases; cystathionine beta-lyase 240358 metC 3171537 metC Anaplasma marginale str. St. Maries cystathionine beta-lyase YP_153635.1 239132 R 234826 CDS YP_153636.1 56416562 3171919 complement(240312..240785) 1 NC_004842.2 COG0271 BolA stress-induced morphogen (activity unknown); bolA like protein 240785 bolA 3171919 bolA Anaplasma marginale str. St. Maries bolA like protein YP_153636.1 240312 R 234826 CDS YP_153637.1 56416563 3171484 240922..241857 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210378.1; hypothetical protein 241857 3171484 AM286 Anaplasma marginale str. St. Maries hypothetical protein YP_153637.1 240922 D 234826 CDS YP_153638.1 56416564 3171610 242268..245651 1 NC_004842.2 COG0587 DnaE DNA polymerase III subunit alpha; DNA polymerase III subunit alpha 245651 dnaE 3171610 dnaE Anaplasma marginale str. St. Maries DNA polymerase III subunit alpha YP_153638.1 242268 D 234826 CDS YP_153639.1 56416565 3171878 245891..247279 1 NC_004842.2 COG0128 AroA 5-enolpyruvylshikimate-3-phosphate synthase; 3-phosphoshikimate 1-carboxyvinyltransferase 247279 rrs 3171878 rrs Anaplasma marginale str. St. Maries 3-phosphoshikimate 1-carboxyvinyltransferase YP_153639.1 245891 D 234826 CDS YP_153640.1 56416566 3171064 249067..249450 1 NC_004842.2 COG2009 SdhC succinate dehydrogenase/fumarate reductase cytochrome b subunit; similar to AAL60178.1; succinate dehydrogenase cytochrome b556 subunit 249450 sdhC 3171064 sdhC Anaplasma marginale str. St. Maries succinate dehydrogenase cytochrome b556 subunit YP_153640.1 249067 D 234826 CDS YP_153641.1 56416567 3171608 complement(249312..249686) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 249686 3171608 AM291 Anaplasma marginale str. St. Maries hypothetical protein YP_153641.1 249312 R 234826 CDS YP_153642.1 56416568 3171003 249441..249791 1 NC_004842.2 COG2142 SdhD succinate dehydrogenase hydrophobic anchor subunit; succinate dehyrdrogenase subunit D 249791 sdhD 3171003 sdhD Anaplasma marginale str. St. Maries succinate dehyrdrogenase subunit D YP_153642.1 249441 D 234826 CDS YP_153643.1 56416569 3171714 249942..251312 1 NC_004842.2 similar to AAS89251.2; hypothetical protein 251312 pep1 3171714 pep1 Anaplasma marginale str. St. Maries hypothetical protein YP_153643.1 249942 D 234826 CDS YP_153644.1 56416570 3171252 complement(251856..252638) 1 NC_004842.2 COG0351 ThiD hydroxymethylpyrimidine/phosphomethylpyrimidine kinase; similar to NP_422017.1; phosphomethylpyrimidine kinase 252638 thiD 3171252 thiD Anaplasma marginale str. St. Maries phosphomethylpyrimidine kinase YP_153644.1 251856 R 234826 CDS YP_153645.1 56416571 3171288 complement(252646..253311) 1 NC_004842.2 conserved family - ATPase involved in DNA replication; hypothetical protein 253311 3171288 AM296 Anaplasma marginale str. St. Maries hypothetical protein YP_153645.1 252646 R 234826 CDS YP_153646.1 56416572 3171702 complement(253312..254664) 1 NC_004842.2 COG0628 PerM predicted permease; similar to NP_385291.1; permease perM-like 254664 perM 3171702 perM Anaplasma marginale str. St. Maries permease perM-like YP_153646.1 253312 R 234826 CDS YP_153647.1 56416573 3171914 complement(254937..255290) 1 NC_004842.2 conserved hypothetical protein similar to NP_966181.1; hypothetical protein 255290 3171914 AM299 Anaplasma marginale str. St. Maries hypothetical protein YP_153647.1 254937 R 234826 CDS YP_153648.1 56416574 3171128 255537..256073 1 NC_004842.2 Binds directly to 16S rRNA where it nucleates assembly of the 30S subunit; 30S ribosomal protein S4 256073 rpsD 3171128 rpsD Anaplasma marginale str. St. Maries 30S ribosomal protein S4 YP_153648.1 255537 D 234826 CDS YP_153649.1 56416575 3171176 complement(256490..257638) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210366.1; hypothetical protein 257638 3171176 AM302 Anaplasma marginale str. St. Maries hypothetical protein YP_153649.1 256490 R 234826 CDS YP_153650.1 56416576 3171392 complement(257698..258471) 1 NC_004842.2 conserved family - acetyltransferase; hypothetical protein 258471 3171392 AM303 Anaplasma marginale str. St. Maries hypothetical protein YP_153650.1 257698 R 234826 CDS YP_153651.1 56416577 3171601 complement(258486..259010) 1 NC_004842.2 COG1267 PgpA phosphatidlglycerophosphatase A; phosphatidylglycerophosphatase A 259010 pgpA 3171601 pgpA Anaplasma marginale str. St. Maries phosphatidylglycerophosphatase A YP_153651.1 258486 R 234826 CDS YP_153652.1 56416578 3170975 complement(259077..259331) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 259331 3170975 AM306 Anaplasma marginale str. St. Maries hypothetical protein YP_153652.1 259077 R 234826 CDS YP_153653.1 56416579 3171486 259718..261118 1 NC_004842.2 COG0544 Tig FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor); similar to NP_420771.1; trigger factor 261118 tig 3171486 tig Anaplasma marginale str. St. Maries trigger factor YP_153653.1 259718 D 234826 CDS YP_153654.1 56416580 3171752 261123..261770 1 NC_004842.2 hydrolyzes proteins to small peptides; with the ATPase subunits ClpA or ClpX, ClpP degrades specific substrates; ATP-dependent Clp protease proteolytic subunit 261770 clpP 3171752 clpP Anaplasma marginale str. St. Maries ATP-dependent Clp protease proteolytic subunit YP_153654.1 261123 D 234826 CDS YP_153655.1 56416581 3171228 261780..262997 1 NC_004842.2 binds and unfolds substrates as part of the ClpXP protease; ATP-dependent protease ATP-binding subunit ClpX 262997 clpX 3171228 clpX Anaplasma marginale str. St. Maries ATP-dependent protease ATP-binding subunit ClpX YP_153655.1 261780 D 234826 CDS YP_153656.1 56416582 3171410 263016..265442 1 NC_004842.2 COG0466 Lon ATP-dependent Lon protease bacterial type; ATP-dependent protease LA 265442 lon 3171410 lon Anaplasma marginale str. St. Maries ATP-dependent protease LA YP_153656.1 263016 D 234826 CDS YP_153657.1 56416583 3171728 265965..266870 1 NC_004842.2 COG0223 Fmt methionyl-tRNA formyltransferase; methionyl-tRNA formyltransferase 266870 fmt 3171728 fmt Anaplasma marginale str. St. Maries methionyl-tRNA formyltransferase YP_153657.1 265965 D 234826 CDS YP_153658.1 56416584 3171471 267028..267861 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210358.1; hypothetical protein 267861 3171471 AM315 Anaplasma marginale str. St. Maries hypothetical protein YP_153658.1 267028 D 234826 CDS YP_153659.1 56416585 3171841 268029..268904 1 NC_004842.2 conserved hypothetical protein similar to NP_966137.1; hypothetical protein 268904 3171841 AM316 Anaplasma marginale str. St. Maries hypothetical protein YP_153659.1 268029 D 234826 CDS YP_153660.1 56416586 3171800 269317..270339 1 NC_004842.2 COG0352 ThiE thiamine monophosphate synthase; similar to NP_229721.1; thiamin monophosphate synthase 270339 thiE 3171800 thiE Anaplasma marginale str. St. Maries thiamin monophosphate synthase YP_153660.1 269317 D 234826 CDS YP_153661.1 56416587 3171319 complement(270586..271899) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210354.1; hypothetical protein 271899 3171319 AM320 Anaplasma marginale str. St. Maries hypothetical protein YP_153661.1 270586 R 234826 CDS YP_153662.1 56416588 3171833 272040..272318 1 NC_004842.2 conserved hypothetical protein similar to NP_965941.1; hypothetical protein 272318 3171833 AM321 Anaplasma marginale str. St. Maries hypothetical protein YP_153662.1 272040 D 234826 CDS YP_153663.1 56416589 3171534 272293..274566 1 NC_004842.2 COG1674 FtsK DNA segregation ATPase FtsK/SpoIIIE and related proteins; similar to NP_533424.1; cell division protein 274566 ftsK 3171534 ftsK Anaplasma marginale str. St. Maries cell division protein YP_153663.1 272293 D 234826 CDS YP_153664.1 56416590 3171458 complement(274841..275893) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 275893 3171458 AM324 Anaplasma marginale str. St. Maries hypothetical protein YP_153664.1 274841 R 234826 CDS YP_153665.1 56416591 3171923 complement(276120..277298) 1 NC_004842.2 DapATase; functions in arginine biosynthetic pathway; catalyzes the formation of N-acetyl-L-glutamate 5-semialdehyde from 2-oxoglutarate and N(2)-acetyl-L-ornithine; acetylornithine transaminase 277298 argD 3171923 argD Anaplasma marginale str. St. Maries acetylornithine transaminase YP_153665.1 276120 R 234826 CDS YP_153666.1 56416592 3171767 277480..278886 1 NC_004842.2 COG0642 BaeS signal transduction histidine kinase; similar to NP_220615.1; histidine kinase sensor protein 278886 barA 3171767 barA Anaplasma marginale str. St. Maries histidine kinase sensor protein YP_153666.1 277480 D 234826 CDS YP_153667.1 56416593 3171772 complement(278900..279751) 1 NC_004842.2 conserved hypothetical protein similar to NP_966025.1; hypothetical protein 279751 3171772 AM328 Anaplasma marginale str. St. Maries hypothetical protein YP_153667.1 278900 R 234826 CDS YP_153668.1 56416594 3171116 complement(279717..280193) 1 NC_004842.2 N: COG0848 ExbD biopolymer transport protein; TolR protein 280193 tolR 3171116 tolR Anaplasma marginale str. St. Maries TolR protein YP_153668.1 279717 R 234826 CDS YP_153669.1 56416595 3171323 complement(280174..280866) 1 NC_004842.2 COG0811 TolQ biopolymer transport protein; TolQ protein 280866 tolQ 3171323 tolQ Anaplasma marginale str. St. Maries TolQ protein YP_153669.1 280174 R 234826 CDS YP_153670.1 56416596 3171130 281043..282227 1 NC_004842.2 COG0323 MutL DNA mismatch repair enzyme (predicted ATPase); open reading frame split domain with AM333; DNA mismatch repair protein 282227 mutL 3171130 mutL Anaplasma marginale str. St. Maries DNA mismatch repair protein YP_153670.1 281043 D 234826 CDS YP_153671.1 56416597 3171120 282274..282939 1 NC_004842.2 COG0323 MutL DNA mismatch repair enzyme (predicted ATPase); open reading frame split domain with AM332; DNA mismatch repair protein 282939 mutL 3171120 mutL Anaplasma marginale str. St. Maries DNA mismatch repair protein YP_153671.1 282274 D 234826 CDS YP_153672.1 56416598 3171256 complement(282953..284086) 1 NC_004842.2 COG0758 Smf predicted Rossmann fold nucleotide-binding protein involved in DNA uptake; DNA processing protein subunit A 284086 smf 3171256 smf Anaplasma marginale str. St. Maries DNA processing protein subunit A YP_153672.1 282953 R 234826 CDS YP_153673.1 56416599 3170961 complement(284565..285728) 1 NC_004842.2 catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs; tRNA-specific 2-thiouridylase MnmA 285728 mnmA 3170961 mnmA Anaplasma marginale str. St. Maries tRNA-specific 2-thiouridylase MnmA YP_153673.1 284565 R 234826 CDS YP_153674.1 56416600 3171663 complement(285916..286938) 1 NC_004842.2 conserved family - twitching mobility protein; hypothetical protein 286938 3171663 AM336 Anaplasma marginale str. St. Maries hypothetical protein YP_153674.1 285916 R 234826 CDS YP_153675.1 56416601 3171750 complement(287239..288522) 1 NC_004842.2 COG0304 FabB 3-oxoacyl-(ACP synthase); 3-oxoacyl-ACP synthase 288522 fabB 3171750 fabB Anaplasma marginale str. St. Maries 3-oxoacyl-ACP synthase YP_153675.1 287239 R 234826 CDS YP_153676.1 56416602 3171665 complement(288627..288974) 1 NC_004842.2 COG0236 AcpP ACP; similar to NP_221115.1; acyl-carrier protein 288974 acpP 3171665 acpP Anaplasma marginale str. St. Maries acyl-carrier protein YP_153676.1 288627 R 234826 CDS YP_153677.1 56416603 3171079 complement(289573..289743) 1 NC_004842.2 in Escherichia coli BM108, a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function; there are paralogous genes in several bacterial genomes, and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31; the proteins in this group lack the CXXC motif; 50S ribosomal protein L33 289743 rpmG 3171079 rpmG Anaplasma marginale str. St. Maries 50S ribosomal protein L33 YP_153677.1 289573 R 234826 CDS YP_153678.1 56416604 3171539 289888..290631 1 NC_004842.2 conserved hypothetical protein similar to NP_965975.1; hypothetical protein 290631 3171539 AM342 Anaplasma marginale str. St. Maries hypothetical protein YP_153678.1 289888 D 234826 CDS YP_153679.1 56416605 3171354 290619..291137 1 NC_004842.2 conserved family - disulfide bond formation protein; hypothetical protein 291137 3171354 AM343 Anaplasma marginale str. St. Maries hypothetical protein YP_153679.1 290619 D 234826 CDS YP_153680.1 56416606 3171907 291311..291622 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 291622 3171907 AM345 Anaplasma marginale str. St. Maries hypothetical protein YP_153680.1 291311 D 234826 CDS YP_153681.1 56416607 3171807 292131..292970 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 292970 3171807 AM346 Anaplasma marginale str. St. Maries hypothetical protein YP_153681.1 292131 D 234826 CDS YP_153682.1 56416608 3171844 complement(293135..296737) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 296737 3171844 AM347 Anaplasma marginale str. St. Maries hypothetical protein YP_153682.1 293135 R 234826 CDS YP_153683.1 56416609 3171215 296823..297086 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 297086 3171215 AM348 Anaplasma marginale str. St. Maries hypothetical protein YP_153683.1 296823 D 234826 CDS YP_153684.1 56416610 3171829 297076..297588 1 NC_004842.2 COG2941 CAT5 ubiquinone biosynthesis protein COQ7; ubiquinone biosynthesis protein 297588 coq7 3171829 coq7 Anaplasma marginale str. St. Maries ubiquinone biosynthesis protein YP_153684.1 297076 D 234826 CDS YP_153685.1 56416611 3171449 297645..298130 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 298130 3171449 AM351 Anaplasma marginale str. St. Maries hypothetical protein YP_153685.1 297645 D 234826 CDS YP_153686.1 56416612 3170943 complement(298247..300946) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 300946 3170943 AM354 Anaplasma marginale str. St. Maries hypothetical protein YP_153686.1 298247 R 234826 CDS YP_153687.1 56416613 3171438 complement(301069..305679) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 305679 3171438 AM356 Anaplasma marginale str. St. Maries hypothetical protein YP_153687.1 301069 R 234826 CDS YP_153688.1 56416614 3171701 complement(305687..305917) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 305917 3171701 AM357 Anaplasma marginale str. St. Maries hypothetical protein YP_153688.1 305687 R 234826 CDS YP_153689.1 56416615 3171516 complement(306198..310316) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 310316 3171516 AM359 Anaplasma marginale str. St. Maries hypothetical protein YP_153689.1 306198 R 234826 CDS YP_153690.1 56416616 3171839 complement(310609..310893) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 310893 3171839 AM360 Anaplasma marginale str. St. Maries hypothetical protein YP_153690.1 310609 R 234826 CDS YP_153691.1 56416617 3171132 complement(311228..319747) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 319747 3171132 AM366 Anaplasma marginale str. St. Maries hypothetical protein YP_153691.1 311228 R 234826 CDS YP_153692.1 56416618 3171513 complement(320035..323076) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 323076 3171513 AM368 Anaplasma marginale str. St. Maries hypothetical protein YP_153692.1 320035 R 234826 CDS YP_153693.1 56416619 3171149 complement(323519..325534) 1 NC_004842.2 COG0210 UvrD superfamily I DNA and RNA helicases; DNA helicase II 325534 uvrD 3171149 uvrD Anaplasma marginale str. St. Maries DNA helicase II YP_153693.1 323519 R 234826 CDS YP_153694.1 56416620 3171094 325806..327449 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 327449 3171094 AM371 Anaplasma marginale str. St. Maries hypothetical protein YP_153694.1 325806 D 234826 CDS YP_153695.1 56416621 3171304 328606..331332 1 NC_004842.2 negatively supercoils closed circular double-stranded DNA; DNA gyrase subunit A 331332 gyrA 3171304 gyrA Anaplasma marginale str. St. Maries DNA gyrase subunit A YP_153695.1 328606 D 234826 CDS YP_153696.1 56416622 3171035 331332..331964 1 NC_004842.2 COG0177 Nth predicted EndoIII-related endonuclease; endonuclease III 331964 nth 3171035 nth Anaplasma marginale str. St. Maries endonuclease III YP_153696.1 331332 D 234826 CDS YP_153697.1 56416623 3171635 332283..332888 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 332888 3171635 AM375 Anaplasma marginale str. St. Maries hypothetical protein YP_153697.1 332283 D 234826 CDS YP_153698.1 56416624 3171358 332974..334890 1 NC_004842.2 molecular chaperone; heat shock protein 90 334890 htpG 3171358 htpG Anaplasma marginale str. St. Maries heat shock protein 90 YP_153698.1 332974 D 234826 CDS YP_153699.1 56416625 3171710 335136..335516 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 335516 3171710 AM378 Anaplasma marginale str. St. Maries hypothetical protein YP_153699.1 335136 D 234826 CDS YP_153700.1 56416626 3171869 335631..336011 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 336011 3171869 AM380 Anaplasma marginale str. St. Maries hypothetical protein YP_153700.1 335631 D 234826 CDS YP_153701.1 56416627 3171287 complement(336686..337396) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 337396 3171287 AM382 Anaplasma marginale str. St. Maries hypothetical protein YP_153701.1 336686 R 234826 CDS YP_153702.1 56416628 3171596 complement(338112..339428) 1 NC_004842.2 Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide; adenylosuccinate lyase 339428 purB 3171596 purB Anaplasma marginale str. St. Maries adenylosuccinate lyase YP_153702.1 338112 R 234826 CDS YP_153703.1 56416629 3171404 340263..342104 1 NC_004842.2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision; excinuclease ABC subunit C 342104 uvrC 3171404 uvrC Anaplasma marginale str. St. Maries excinuclease ABC subunit C YP_153703.1 340263 D 234826 CDS YP_153704.1 56416630 3171316 complement(342230..346690) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 346690 3171316 AM387 Anaplasma marginale str. St. Maries hypothetical protein YP_153704.1 342230 R 234826 CDS YP_153705.1 56416631 3171299 complement(347150..347878) 1 NC_004842.2 COG0340 BirA biotin-(acetyl-CoA carboxylase ligase); biotin-(acetyl-CoA carboxylase) 347878 birA 3171299 birA Anaplasma marginale str. St. Maries biotin-(acetyl-CoA carboxylase) YP_153705.1 347150 R 234826 CDS YP_153706.1 56416632 3171201 complement(347887..348555) 1 NC_004842.2 COG0625 Gst glutathione-S-transferases; similar to NP_360419.1; glutathione S-transferase 348555 gst 3171201 gst Anaplasma marginale str. St. Maries glutathione S-transferase YP_153706.1 347887 R 234826 CDS YP_153707.1 56416633 3171305 complement(348638..349180) 1 NC_004842.2 conserved hypothetical protein similar to BAA36355.1; hypothetical protein 349180 3171305 AM391 Anaplasma marginale str. St. Maries hypothetical protein YP_153707.1 348638 R 234826 CDS YP_153708.1 56416634 3171548 349511..350587 1 NC_004842.2 conserved family - ABC transporter; hypothetical protein 350587 3171548 AM392 Anaplasma marginale str. St. Maries hypothetical protein YP_153708.1 349511 D 234826 CDS YP_153709.1 56416635 3171790 350796..351437 1 NC_004842.2 involved in a recombinational process of DNA repair, independent of the recBC complex; recombination protein RecR 351437 recR 3171790 recR Anaplasma marginale str. St. Maries recombination protein RecR YP_153709.1 350796 D 234826 CDS YP_153710.1 56416636 3171032 complement(351434..351706) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 351706 3171032 AM395 Anaplasma marginale str. St. Maries hypothetical protein YP_153710.1 351434 R 234826 CDS YP_153711.1 56416637 3171043 complement(351826..352710) 1 NC_004842.2 COG0803 ZnuA ABC-type Mn/Zn transport system periplasmic Mn/Zn-binding (lipo)protein (surface adhesin); similar to NP_541155.1; high-affinity zinc uptake system protein 352710 znuA 3171043 znuA Anaplasma marginale str. St. Maries high-affinity zinc uptake system protein YP_153711.1 351826 R 234826 CDS YP_153712.1 56416638 3171813 352690..353427 1 NC_004842.2 COG1121 ZnuC ABC-type Mn/Zn transport systems ATPase component; similar to NP_759163.1; zinc ABC transporter ATP-binding protein 353427 znuC 3171813 znuC Anaplasma marginale str. St. Maries zinc ABC transporter ATP-binding protein YP_153712.1 352690 D 234826 CDS YP_153713.1 56416639 3171536 353420..354871 1 NC_004842.2 COG0543 UbiB 2-polyprenylphenol hydroxylase; similar to NP_541211.1; ubiquinone biosynthesis protein 354871 ubiB 3171536 ubiB Anaplasma marginale str. St. Maries ubiquinone biosynthesis protein YP_153713.1 353420 D 234826 CDS YP_153714.1 56416640 3170997 354909..356114 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210709.1; hypothetical protein 356114 3170997 AM400 Anaplasma marginale str. St. Maries hypothetical protein YP_153714.1 354909 D 234826 CDS YP_153715.1 56416641 3171615 complement(356277..357644) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00142641.1; hypothetical protein 357644 3171615 AM401 Anaplasma marginale str. St. Maries hypothetical protein YP_153715.1 356277 R 234826 CDS YP_153716.1 56416642 3171009 complement(357781..360423) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210707.1; hypothetical protein 360423 3171009 AM402 Anaplasma marginale str. St. Maries hypothetical protein YP_153716.1 357781 R 234826 CDS YP_153717.1 56416643 3170950 complement(360719..361549) 1 NC_004842.2 conserved hypothetical protein similar to NP_966505.1; hypothetical protein 361549 3170950 AM404 Anaplasma marginale str. St. Maries hypothetical protein YP_153717.1 360719 R 234826 CDS YP_153718.1 56416644 3171498 361688..364480 1 NC_004842.2 SucA; E1 component of the oxoglutarate dehydrogenase complex which catalyzes the formation of succinyl-CoA from 2-oxoglutarate; SucA catalyzes the reaction of 2-oxoglutarate with dihydrolipoamide succinyltransferase-lipoate to form dihydrolipoamide succinyltransferase-succinyldihydrolipoate and carbon dioxide; 2-oxoglutarate dehydrogenase E1 component 364480 sucA 3171498 sucA Anaplasma marginale str. St. Maries 2-oxoglutarate dehydrogenase E1 component YP_153718.1 361688 D 234826 CDS YP_153719.1 56416645 3171494 complement(365054..366205) 1 NC_004842.2 conserved family - phage major capsid protein; hypothetical protein 366205 3171494 AM406 Anaplasma marginale str. St. Maries hypothetical protein YP_153719.1 365054 R 234826 CDS YP_153720.1 56416646 3171207 complement(366422..367327) 1 NC_004842.2 catalyzes the formation of dihydrodipicolinate from L-aspartate 4-semialdehyde and pyruvate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate synthase 367327 dapA 3171207 dapA Anaplasma marginale str. St. Maries dihydrodipicolinate synthase YP_153720.1 366422 R 234826 CDS YP_153721.1 56416647 3171736 complement(367524..367895) 1 NC_004842.2 protein kinase C inhibitor 1 (pkcI ); similar to EAA25530.1; protein kinase C inhibitor 1 367895 pkcI 3171736 pkcI Anaplasma marginale str. St. Maries protein kinase C inhibitor 1 YP_153721.1 367524 R 234826 CDS YP_153722.1 56416648 3171026 complement(367892..369142) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 369142 3171026 AM410 Anaplasma marginale str. St. Maries hypothetical protein YP_153722.1 367892 R 234826 CDS YP_153723.1 56416649 3171124 369479..371938 1 NC_004842.2 This protein performs the mismatch recognition step during the DNA repair process; DNA mismatch repair protein MutS 371938 mutS 3171124 mutS Anaplasma marginale str. St. Maries DNA mismatch repair protein MutS YP_153723.1 369479 D 234826 CDS YP_153724.1 56416650 3171756 371919..372203 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 372203 3171756 AM413 Anaplasma marginale str. St. Maries hypothetical protein YP_153724.1 371919 D 234826 CDS YP_153725.1 56416651 3171213 372351..373721 1 NC_004842.2 conserved family - sugar and other transporter; high sequence identity to AM415, may be a duplicate gene; hypothetical protein 373721 3171213 AM414 Anaplasma marginale str. St. Maries hypothetical protein YP_153725.1 372351 D 234826 CDS YP_153726.1 56416652 3171004 373831..375153 1 NC_004842.2 conserved family - sugar and other transporter; high sequence identity to AM414, may be a duplicate gene; hypothetical protein 375153 3171004 AM415 Anaplasma marginale str. St. Maries hypothetical protein YP_153726.1 373831 D 234826 CDS YP_153727.1 56416653 3171122 complement(375143..376663) 1 NC_004842.2 COG0171 NadE NAD synthase; NH3-dependent NAD+ synthetase protein 376663 nadE 3171122 nadE Anaplasma marginale str. St. Maries NH3-dependent NAD+ synthetase protein YP_153727.1 375143 R 234826 CDS YP_153728.1 56416654 3171077 complement(376670..377710) 1 NC_004842.2 catalyzes the formation of porphobilinogen from 5-aminolevulinate; delta-aminolevulinic acid dehydratase 377710 hemB 3171077 hemB Anaplasma marginale str. St. Maries delta-aminolevulinic acid dehydratase YP_153728.1 376670 R 234826 CDS YP_153729.1 56416655 3171395 377907..379496 1 NC_004842.2 COG0768 FtsI cell division protein FtsI/penicillin-binding protein 2; penicillin-binding protein 379496 pbpA2 3171395 pbpA2 Anaplasma marginale str. St. Maries penicillin-binding protein YP_153729.1 377907 D 234826 CDS YP_153730.1 56416656 3171808 379536..382376 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210697.1; hypothetical protein 382376 3171808 AM419 Anaplasma marginale str. St. Maries hypothetical protein YP_153730.1 379536 D 234826 CDS YP_153731.1 56416657 3171382 382538..384001 1 NC_004842.2 conserved family - permease of the major facilitator superfamily; hypothetical protein 384001 3171382 AM420 Anaplasma marginale str. St. Maries hypothetical protein YP_153731.1 382538 D 234826 CDS YP_153732.1 56416658 3171114 complement(384373..384912) 1 NC_004842.2 COG0629 Ssb single-stranded DNA-binding protein; similar to NP_771338.1; single-strand binding protein 384912 ssb 3171114 ssb Anaplasma marginale str. St. Maries single-strand binding protein YP_153732.1 384373 R 234826 CDS YP_153733.1 56416659 3170973 385083..386465 1 NC_004842.2 malonyl-CoA decarboxylase 386465 mcd 3170973 mcd Anaplasma marginale str. St. Maries malonyl-CoA decarboxylase YP_153733.1 385083 D 234826 CDS YP_153734.1 56416660 3171857 386478..387935 1 NC_004842.2 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit B 387935 gatB 3171857 gatB Anaplasma marginale str. St. Maries aspartyl/glutamyl-tRNA amidotransferase subunit B YP_153734.1 386478 D 234826 CDS YP_153735.1 56416661 3171150 388435..389283 1 NC_004842.2 COG0623 FabI enoyl-[ACP] reductase (NADH); similar to NP_385004.1; enoyl-[ACP] reductase 389283 fabI 3171150 fabI Anaplasma marginale str. St. Maries enoyl-[ACP] reductase YP_153735.1 388435 D 234826 CDS YP_153736.1 56416662 3171543 389525..390940 1 NC_004842.2 binds to the dnaA-box as an ATP-bound complex at the origin of replication during the initiation of chromosomal replication; can also affect transcription of multiple genes including itself.; chromosomal replication initiation protein 390940 dnaA 3171543 dnaA Anaplasma marginale str. St. Maries chromosomal replication initiation protein YP_153736.1 389525 D 234826 CDS YP_153737.1 56416663 3171419 complement(391044..392039) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 392039 3171419 AM431 Anaplasma marginale str. St. Maries hypothetical protein YP_153737.1 391044 R 234826 CDS YP_153738.1 56416664 3170948 392119..392823 1 NC_004842.2 conserved family - nicotinic acid mononucleotide adenylyltransferase; hypothetical protein 392823 3170948 AM432 Anaplasma marginale str. St. Maries hypothetical protein YP_153738.1 392119 D 234826 CDS YP_153739.1 56416665 3171900 393003..393764 1 NC_004842.2 involved in the de novo synthesis of pyridoxine (Vitamin B6); pyridoxine 5'-phosphate synthase 393764 pdxJ 3171900 pdxJ Anaplasma marginale str. St. Maries pyridoxine 5'-phosphate synthase YP_153739.1 393003 D 234826 CDS YP_153740.1 56416666 3171519 complement(394935..395825) 1 NC_004842.2 conserved family - DNA polymerase III subunit; hypothetical protein 395825 3171519 AM435 Anaplasma marginale str. St. Maries hypothetical protein YP_153740.1 394935 R 234826 CDS YP_153741.1 56416667 3171540 complement(395807..396400) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210684.1; hypothetical protein 396400 3171540 AM436 Anaplasma marginale str. St. Maries hypothetical protein YP_153741.1 395807 R 234826 CDS YP_153742.1 56416668 3171571 397133..397849 1 NC_004842.2 COG0237 CoaE dephospho-CoA kinase; dephospho-CoA kinase 397849 coaE 3171571 coaE Anaplasma marginale str. St. Maries dephospho-CoA kinase YP_153742.1 397133 D 234826 CDS YP_153743.1 56416669 3171678 complement(397898..399700) 1 NC_004842.2 required for the synthesis of the hydromethylpyrimidine moiety of thiamine; thiamine biosynthesis protein ThiC 399700 thiC 3171678 thiC Anaplasma marginale str. St. Maries thiamine biosynthesis protein ThiC YP_153743.1 397898 R 234826 CDS YP_153744.1 56416670 3171067 complement(399744..400409) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210681.1; hypothetical protein 400409 3171067 AM441 Anaplasma marginale str. St. Maries hypothetical protein YP_153744.1 399744 R 234826 CDS YP_153745.1 56416671 3171461 complement(400474..400860) 1 NC_004842.2 COG1758 RpoZ DNA-directed RNA polymerase subunit K/omega; DNA-directed RNA polymerase subunit omega 400860 rpoZ 3171461 rpoZ Anaplasma marginale str. St. Maries DNA-directed RNA polymerase subunit omega YP_153745.1 400474 R 234826 CDS YP_153746.1 56416672 3171405 complement(401195..401518) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210679.1; hypothetical protein 401518 3171405 AM445 Anaplasma marginale str. St. Maries hypothetical protein YP_153746.1 401195 R 234826 CDS YP_153747.1 56416673 3171345 401901..404390 1 NC_004842.2 leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; leucyl-tRNA synthetase 404390 leuS 3171345 leuS Anaplasma marginale str. St. Maries leucyl-tRNA synthetase YP_153747.1 401901 D 234826 CDS YP_153748.1 56416674 3171926 404701..405489 1 NC_004842.2 conserved family - Mg-dependent DNase; hypothetical protein 405489 3171926 AM447 Anaplasma marginale str. St. Maries hypothetical protein YP_153748.1 404701 D 234826 CDS YP_153749.1 56416675 3171631 405446..406165 1 NC_004842.2 COG0284 PyrF orotidine-5'-phosphate decarboxylase; orotidine 5'-phosphate decarboxylase 406165 pyrF 3171631 pyrF Anaplasma marginale str. St. Maries orotidine 5'-phosphate decarboxylase YP_153749.1 405446 D 234826 CDS YP_153750.1 56416676 3171916 complement(406258..406680) 1 NC_004842.2 CycJ; periplasmic heme chaperone that binds heme transiently via a histidine residue and delivers it to newly synthesized and exported c-type cytochromes; requires the ATP hydrolysis activity of the CcmA protein in order to transfer the heme to the apocytochrome; part of the cytochrome C maturation system; periplasmic protein anchored to the inner membrane; cytochrome C-type biogenesis protein CcmE 406680 ccmE 3171916 ccmE Anaplasma marginale str. St. Maries cytochrome C-type biogenesis protein CcmE YP_153750.1 406258 R 234826 CDS YP_153751.1 56416677 3170996 complement(406802..407587) 1 NC_004842.2 COG0496 SurE survival protein, predicted acid phosphatase; stationary-phase survival protein 407587 surE 3170996 surE Anaplasma marginale str. St. Maries stationary-phase survival protein YP_153751.1 406802 R 234826 CDS YP_153752.1 56416678 3171394 complement(408316..408879) 1 NC_004842.2 COG0852 NuoC NADH:ubiquinone oxidoreductase 27 kD subunit; NADH-ubiquinone oxidoreductase subunit 408879 nuoC1 3171394 nuoC1 Anaplasma marginale str. St. Maries NADH-ubiquinone oxidoreductase subunit YP_153752.1 408316 R 234826 CDS YP_153753.1 56416679 3171030 complement(408885..409412) 1 NC_004842.2 The point of entry for the majority of electrons that traverse the respiratory chain eventually resulting in the reduction of oxygen; NADH dehydrogenase subunit B 409412 nuoB 3171030 nuoB Anaplasma marginale str. St. Maries NADH dehydrogenase subunit B YP_153753.1 408885 R 234826 CDS YP_153754.1 56416680 3171709 complement(409417..409824) 1 NC_004842.2 COG0838 NuoA NADH:ubiquinone oxidoreductase subunit 3 (chain A); NADH dehydrogenase I subunit A 409824 nuoA 3171709 nuoA Anaplasma marginale str. St. Maries NADH dehydrogenase I subunit A YP_153754.1 409417 R 234826 CDS YP_153755.1 56416681 3170994 complement(410141..413011) 1 NC_004842.2 COG0178 UvrA excinuclease ATPase subunit; excinuclease ABC subunit A 413011 uvrA 3170994 uvrA Anaplasma marginale str. St. Maries excinuclease ABC subunit A YP_153755.1 410141 R 234826 CDS YP_153756.1 56416682 3171780 complement(413045..413578) 1 NC_004842.2 COG0781 NusB transcription termination factor; N utilization substance protein B 413578 nusB 3171780 nusB Anaplasma marginale str. St. Maries N utilization substance protein B YP_153756.1 413045 R 234826 CDS YP_153757.2 161544991 3171837 complement(413571..414020) 1 NC_004842.2 RibE; 6,7-diimethyl-8-ribityllumazine synthase; DMRL synthase; lumazine synthase; beta subunit of riboflavin synthase; condenses 5-amino-6-(1'-D)-ribityl-amino-2,4(1H,3H)-pyrimidinedione with L-3,4-dihydrohy-2-butanone-4-phosphate to generate 6,6-dimethyl-8-lumazine (DMRL); riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12); involved in the last steps of riboflavin biosynthesis; forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli; in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not; 6,7-dimethyl-8-ribityllumazine synthase 414020 ribH 3171837 ribH Anaplasma marginale str. St. Maries 6,7-dimethyl-8-ribityllumazine synthase YP_153757.2 413571 R 234826 CDS YP_153758.2 161544990 3171335 complement(414052..415770) 1 NC_004842.2 functions to insert inner membrane proteins into the IM in Escherichia coli; interacts with transmembrane segments; functions in both Sec-dependent and -independent membrane insertion; similar to Oxa1p in mitochondria; inner membrane protein translocase component YidC 415770 yidC 3171335 yidC Anaplasma marginale str. St. Maries inner membrane protein translocase component YidC YP_153758.2 414052 R 234826 CDS YP_153759.1 56416685 3171748 complement(416086..416928) 1 NC_004842.2 COG1183 PssA phosphatidylserine synthase; CDP-diacylglycerol--serine O-phosphatidyltransferase 416928 pssA 3171748 pssA Anaplasma marginale str. St. Maries CDP-diacylglycerol--serine O-phosphatidyltransferase YP_153759.1 416086 R 234826 CDS YP_153760.1 56416686 3171333 complement(416989..417693) 1 NC_004842.2 catalyzes the decarboxylaton of phospatidyl-L-sering to phosphatidylethanolamine; phosphatidylserine decarboxylase 417693 psd 3171333 psd Anaplasma marginale str. St. Maries phosphatidylserine decarboxylase YP_153760.1 416989 R 234826 CDS YP_153761.1 56416687 3171047 complement(417952..421353) 1 NC_004842.2 conserved hypothetical protein similar to NP_840932.1; hypothetical protein 421353 3171047 AM465 Anaplasma marginale str. St. Maries hypothetical protein YP_153761.1 417952 R 234826 CDS YP_153762.1 56416688 3171864 complement(421771..425556) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 425556 3171864 AM470 Anaplasma marginale str. St. Maries hypothetical protein YP_153762.1 421771 R 234826 CDS YP_153763.1 56416689 3171244 425738..426856 1 NC_004842.2 COG0707 MurG UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase; similar to NP_421354.1; UDP-N-acetylglucosamine-N-acetylmuramyl- (pentapeptide pyrophosphoryl-undecaprenol N-acetylglucosamine) 426856 murG 3171244 murG Anaplasma marginale str. St. Maries UDP-N-acetylglucosamine-N-acetylmuramyl- (pentapeptide pyrophosphoryl-undecaprenol N-acetylglucosamine) YP_153763.1 425738 D 234826 CDS YP_153764.1 56416690 3171738 427002..427568 1 NC_004842.2 COG0231 Efp translation elongation factor P; translation initiation factor eIF-5A; elongation factor PEF-P 427568 efp 3171738 efp Anaplasma marginale str. St. Maries elongation factor PEF-P YP_153764.1 427002 D 234826 CDS YP_153765.1 56416691 3171082 427571..428332 1 NC_004842.2 COG0483 SuhB Archaeal fructose-1,6-bisphosphatase and related enzymes of; similar to NP_104922.1; extragenic suppressor protein 428332 suhB 3171082 suhB Anaplasma marginale str. St. Maries extragenic suppressor protein YP_153765.1 427571 D 234826 CDS YP_153766.1 56416692 3171427 428329..429219 1 NC_004842.2 COG0564 RluA pseudouridylate synthases, 23S RNA-specific; ribosomal large subunit pseudouridine synthase 429219 rluC 3171427 rluC Anaplasma marginale str. St. Maries ribosomal large subunit pseudouridine synthase YP_153766.1 428329 D 234826 CDS YP_153767.1 56416693 3171125 complement(429469..430836) 1 NC_004842.2 involved in swarmer-to-stalked cell differentiation in Caulobacter crescentus; catalyzes the condensation of two GTP molecules to form the secondary messenger cyclic di-GMP (c-di-GMP); upon phosphorylation of domain D1 the protein dimerizes; presumably this allows the two GTP-bound GGDEF (diguanylate cyclase) domains to catalyze the condensation reaction; allosterically inhibited by c-di-GMP; response regulator PleD 430836 pleD 3171125 pleD Anaplasma marginale str. St. Maries response regulator PleD YP_153767.1 429469 R 234826 CDS YP_153768.1 56416694 3170988 complement(431033..431419) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210656.1; hypothetical protein 431419 3170988 AM476 Anaplasma marginale str. St. Maries hypothetical protein YP_153768.1 431033 R 234826 CDS YP_153769.1 56416695 3171254 complement(431385..436238) 1 NC_004842.2 conserved family - NAD-specific glutamate dehydrogenase; hypothetical protein 436238 3171254 AM477 Anaplasma marginale str. St. Maries hypothetical protein YP_153769.1 431385 R 234826 CDS YP_153770.1 56416696 3171161 436634..437359 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210654.1; hypothetical protein 437359 3171161 AM480 Anaplasma marginale str. St. Maries hypothetical protein YP_153770.1 436634 D 234826 CDS YP_153771.1 56416697 3171872 437361..438761 1 NC_004842.2 catalyzes a two-step reaction; charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA; cysteinyl-tRNA synthetase 438761 cysS 3171872 cysS Anaplasma marginale str. St. Maries cysteinyl-tRNA synthetase YP_153771.1 437361 D 234826 CDS YP_153772.1 56416698 3171897 439009..439983 1 NC_004842.2 B2 or R2 protein; type 1b enzyme; catalyzes the rate-limiting step in dNTP synthesis; converts nucleotides to deoxynucleotides; forms a homodimer and then a multimeric complex with NrdE; ribonucleotide-diphosphate reductase subunit beta 439983 nrdF 3171897 nrdF Anaplasma marginale str. St. Maries ribonucleotide-diphosphate reductase subunit beta YP_153772.1 439009 D 234826 CDS YP_153773.1 56416699 3171016 439961..440560 1 NC_004842.2 conserved family - thiol:disulfide interchange protein; hypothetical protein 440560 3171016 AM485 Anaplasma marginale str. St. Maries hypothetical protein YP_153773.1 439961 D 234826 CDS YP_153774.1 56416700 3171803 complement(441151..441435) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210650.1; hypothetical protein 441435 3171803 AM486 Anaplasma marginale str. St. Maries hypothetical protein YP_153774.1 441151 R 234826 CDS YP_153775.1 56416701 3171459 441651..442682 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210648.1; hypothetical protein 442682 3171459 AM487 Anaplasma marginale str. St. Maries hypothetical protein YP_153775.1 441651 D 234826 CDS YP_153776.1 56416702 3171158 442810..444648 1 NC_004842.2 COG0358 DnaG DNA primase (bacterial type); similar to NP_539447.1; DNA primase 444648 dnaG 3171158 dnaG Anaplasma marginale str. St. Maries DNA primase YP_153776.1 442810 D 234826 CDS YP_153777.1 56416703 3171011 444617..444838 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 444838 3171011 AM489 Anaplasma marginale str. St. Maries hypothetical protein YP_153777.1 444617 D 234826 CDS YP_153778.1 56416704 3171104 complement(444813..446711) 1 NC_004842.2 COG0568 RpoD DNA-directed RNA polymerase sigma subunits (sigma70/sigma32); RNA polymerase sigma factor 446711 rpoD 3171104 rpoD Anaplasma marginale str. St. Maries RNA polymerase sigma factor YP_153778.1 444813 R 234826 CDS YP_153779.1 56416705 3171834 complement(446914..447876) 1 NC_004842.2 conserved family - nifR3 like protein; hypothetical protein 447876 3171834 AM492 Anaplasma marginale str. St. Maries hypothetical protein YP_153779.1 446914 R 234826 CDS YP_153780.1 56416706 3171840 448016..448885 1 NC_004842.2 An essential enzyme in the nonmevalonate pathway of isopentenyl diphosphate and dimethylallyl diphosphate biosynthesis; 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase 448885 ispE 3171840 ispE Anaplasma marginale str. St. Maries 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase YP_153780.1 448016 D 234826 CDS YP_153781.1 56416707 3171831 complement(449010..449444) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 449444 3171831 AM495 Anaplasma marginale str. St. Maries hypothetical protein YP_153781.1 449010 R 234826 CDS YP_153782.1 56416708 3171866 complement(449860..450216) 1 NC_004842.2 COG1324 CutA uncharacterized protein involved in tolerance to divalent cations; divalent cation tolerance protein 450216 cutA 3171866 cutA Anaplasma marginale str. St. Maries divalent cation tolerance protein YP_153782.1 449860 R 234826 CDS YP_153783.1 56416709 3171257 complement(450260..452743) 1 NC_004842.2 sensory box histidine kinase/response regulator 452743 dhkA 3171257 dhkA Anaplasma marginale str. St. Maries sensory box histidine kinase/response regulator YP_153783.1 450260 R 234826 CDS YP_153784.1 56416710 3171374 complement(453242..453904) 1 NC_004842.2 conserved family - O-methyltransferase; hypothetical protein 453904 3171374 AM499 Anaplasma marginale str. St. Maries hypothetical protein YP_153784.1 453242 R 234826 CDS YP_153785.1 56416711 3171500 454148..454468 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210640.1; hypothetical protein 454468 3171500 AM500 Anaplasma marginale str. St. Maries hypothetical protein YP_153785.1 454148 D 234826 CDS YP_153786.1 56416712 3171284 454671..456080 1 NC_004842.2 conserved family - predicted sugar kinase; hypothetical protein 456080 3171284 AM501 Anaplasma marginale str. St. Maries hypothetical protein YP_153786.1 454671 D 234826 CDS YP_153787.1 56416713 3171572 456208..458646 1 NC_004842.2 COG0550 TopA topoisomerase IA; DNA topoisomerase 458646 topA 3171572 topA Anaplasma marginale str. St. Maries DNA topoisomerase YP_153787.1 456208 D 234826 CDS YP_153788.1 56416714 3171873 complement(458866..459342) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210636.1; hypothetical protein 459342 3171873 AM504 Anaplasma marginale str. St. Maries hypothetical protein YP_153788.1 458866 R 234826 CDS YP_153789.1 56416715 3171551 complement(460409..460771) 1 NC_004842.2 Catalyzes the formation of holo-ACP, which mediates the essential transfer of acyl fatty acid intermediates during the biosynthesis of fatty acids and lipids; 4'-phosphopantetheinyl transferase 460771 acpS 3171551 acpS Anaplasma marginale str. St. Maries 4'-phosphopantetheinyl transferase YP_153789.1 460409 R 234826 CDS YP_153790.1 56416716 3171578 complement(460768..462045) 1 NC_004842.2 catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro); prolyl-tRNA synthetase 462045 proS 3171578 proS Anaplasma marginale str. St. Maries prolyl-tRNA synthetase YP_153790.1 460768 R 234826 CDS YP_153791.1 56416717 3171798 complement(462309..463361) 1 NC_004842.2 conserved hypothetical protein similar to NP_966301.1; hypothetical protein 463361 3171798 AM508 Anaplasma marginale str. St. Maries hypothetical protein YP_153791.1 462309 R 234826 CDS YP_153792.1 56416718 3171036 463648..464160 1 NC_004842.2 Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA; phosphopantetheine adenylyltransferase 464160 coaD 3171036 coaD Anaplasma marginale str. St. Maries phosphopantetheine adenylyltransferase YP_153792.1 463648 D 234826 CDS YP_153793.1 56416719 3171507 complement(464331..465308) 1 NC_004842.2 COG0492 TrxB thioredoxin reductase; thioredoxin reductase 465308 trxB 3171507 trxB Anaplasma marginale str. St. Maries thioredoxin reductase YP_153793.1 464331 R 234826 CDS YP_153794.1 56416720 3171741 complement(465305..465928) 1 NC_004842.2 COG0450 AhpC peroxiredoxin; similar to NP_360088.1; thioredoxin peroxidase 1 465928 tdpX1 3171741 tdpX1 Anaplasma marginale str. St. Maries thioredoxin peroxidase 1 YP_153794.1 465305 R 234826 CDS YP_153795.1 56416721 3171570 466204..466884 1 NC_004842.2 COG0075 serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; open reading frame split domain with AM515; aspartate aminotransferase A 466884 aatA 3171570 aatA Anaplasma marginale str. St. Maries aspartate aminotransferase A YP_153795.1 466204 D 234826 CDS YP_153796.1 56416722 3171331 466941..467561 1 NC_004842.2 COG0075 serine-pyruvate aminotransferase/archaeal aspartate aminotransferase; open reading frame split domain with AM514; aspartate aminotransferase A 467561 aatA 3171331 aatA Anaplasma marginale str. St. Maries aspartate aminotransferase A YP_153796.1 466941 D 234826 CDS YP_153797.1 56416723 3171558 complement(467807..469819) 1 NC_004842.2 conserved family - peptidyl-prolyl cis-trans isomerase D; hypothetical protein 469819 3171558 AM516 Anaplasma marginale str. St. Maries hypothetical protein YP_153797.1 467807 R 234826 CDS YP_153798.1 56416724 3171865 complement(469871..470464) 1 NC_004842.2 conserved hypothetical protein similar to NP_384508.1; hypothetical protein 470464 3171865 AM517 Anaplasma marginale str. St. Maries hypothetical protein YP_153798.1 469871 R 234826 CDS YP_153799.1 56416725 3171359 complement(470483..471793) 1 NC_004842.2 conserved family - transporter protein; hypothetical protein 471793 3171359 AM518 Anaplasma marginale str. St. Maries hypothetical protein YP_153799.1 470483 R 234826 CDS YP_153800.1 56416726 3171086 complement(471817..473121) 1 NC_004842.2 conserved family - transporter protein; hypothetical protein 473121 3171086 AM520 Anaplasma marginale str. St. Maries hypothetical protein YP_153800.1 471817 R 234826 CDS YP_153801.1 56416727 3171529 473383..474249 1 NC_004842.2 in some organisms this protein is a transmembrane protein while in others it is periplasmic; involved in some organisms with other components of the MreBCD complex and with penicillin binding proteins in the periplasm or cell wall; rod shape-determining protein MreC 474249 mreC 3171529 mreC Anaplasma marginale str. St. Maries rod shape-determining protein MreC YP_153801.1 473383 D 234826 CDS YP_153802.1 56416728 3171463 complement(474358..475467) 1 NC_004842.2 functions in MreBCD complex in some organisms; rod shape-determining protein MreB 475467 mreB 3171463 mreB Anaplasma marginale str. St. Maries rod shape-determining protein MreB YP_153802.1 474358 R 234826 CDS YP_153803.1 56416729 3171734 475701..476621 1 NC_004842.2 COG0130 TruB pseudouridine synthase; tRNA pseudouridine 55 synthase 476621 truB 3171734 truB Anaplasma marginale str. St. Maries tRNA pseudouridine 55 synthase YP_153803.1 475701 D 234826 CDS YP_153804.1 56416730 3171814 476660..476941 1 NC_004842.2 primary rRNA binding protein; helps nucleate assembly of 30S; binds directly to the 16S rRNA and an intersubunit bridge to the 23S rRNA; autoregulates translation through interactions with the mRNA leader sequence; 30S ribosomal protein S15 476941 rpsO 3171814 rpsO Anaplasma marginale str. St. Maries 30S ribosomal protein S15 YP_153804.1 476660 D 234826 CDS YP_153805.1 56416731 3171743 476993..479410 1 NC_004842.2 COG0005 Pnp purine nucleoside phosphorylase; similar to NP_384350.1; polynucleotide phosphorylase/polyadenylase 479410 pnp 3171743 pnp Anaplasma marginale str. St. Maries polynucleotide phosphorylase/polyadenylase YP_153805.1 476993 D 234826 CDS YP_153806.1 56416732 3171628 479416..480192 1 NC_004842.2 conserved hypothetical protein similar to NP_419648.1; hypothetical protein 480192 3171628 AM527 Anaplasma marginale str. St. Maries hypothetical protein YP_153806.1 479416 D 234826 CDS YP_153807.1 56416733 3171773 480327..482126 1 NC_004842.2 binds to the ribosome on the universally-conserved alpha-sarcin loop; GTP-binding protein LepA 482126 lepA 3171773 lepA Anaplasma marginale str. St. Maries GTP-binding protein LepA YP_153807.1 480327 D 234826 CDS YP_153808.1 56416734 3171373 complement(483114..483482) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 483482 3171373 AM529 Anaplasma marginale str. St. Maries hypothetical protein YP_153808.1 483114 R 234826 CDS YP_153809.1 56416735 3171757 483889..485769 1 NC_004842.2 member of msp1 superfamily; major surface protein 1a 485769 msp1a 3171757 msp1a Anaplasma marginale str. St. Maries major surface protein 1a YP_153809.1 483889 D 234826 CDS YP_153810.1 56416736 3171135 486324..487166 1 NC_004842.2 major surface protein 1a-like protein 22 487166 mlp2 3171135 mlp2 Anaplasma marginale str. St. Maries major surface protein 1a-like protein 22 YP_153810.1 486324 D 234826 CDS YP_153811.1 56416737 3171704 487640..488515 1 NC_004842.2 major surface protein 1a-like protein 3 488515 mlp3 3171704 mlp3 Anaplasma marginale str. St. Maries major surface protein 1a-like protein 3 YP_153811.1 487640 D 234826 CDS YP_153812.1 56416738 3171541 488938..489873 1 NC_004842.2 major surface protein 1a-like protein 4 489873 mlp4 3171541 mlp4 Anaplasma marginale str. St. Maries major surface protein 1a-like protein 4 YP_153812.1 488938 D 234826 CDS YP_153813.1 56416739 3171266 489895..490626 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 490626 3171266 AM537 Anaplasma marginale str. St. Maries hypothetical protein YP_153813.1 489895 D 234826 CDS YP_153814.1 56416740 3171910 491451..498992 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 498992 3171910 AM540 Anaplasma marginale str. St. Maries hypothetical protein YP_153814.1 491451 D 234826 CDS YP_153815.1 56416741 3171034 499054..500883 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 500883 3171034 AM541 Anaplasma marginale str. St. Maries hypothetical protein YP_153815.1 499054 D 234826 CDS YP_153816.1 56416742 3171253 501283..503181 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 503181 3171253 AM543 Anaplasma marginale str. St. Maries hypothetical protein YP_153816.1 501283 D 234826 CDS YP_153817.1 56416743 3171890 503759..505636 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 505636 3171890 AM545 Anaplasma marginale str. St. Maries hypothetical protein YP_153817.1 503759 D 234826 CDS YP_153818.1 56416744 3171239 505658..505891 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 505891 3171239 AM546 Anaplasma marginale str. St. Maries hypothetical protein YP_153818.1 505658 D 234826 CDS YP_153819.1 56416745 3171758 506074..507987 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 507987 3171758 AM547 Anaplasma marginale str. St. Maries hypothetical protein YP_153819.1 506074 D 234826 CDS YP_153820.1 56416746 3171448 508787..510619 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 510619 3171448 AM550 Anaplasma marginale str. St. Maries hypothetical protein YP_153820.1 508787 D 234826 CDS YP_153821.1 56416747 3171930 510801..512963 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 512963 3171930 AM551 Anaplasma marginale str. St. Maries hypothetical protein YP_153821.1 510801 D 234826 CDS YP_153822.1 56416748 3171581 complement(512951..513904) 1 NC_004842.2 COG0611 ThiL thiamine monophosphate kinase; similar to NP_439456.1; thiamin-monophosphate kinase 513904 thiL 3171581 thiL Anaplasma marginale str. St. Maries thiamin-monophosphate kinase YP_153822.1 512951 R 234826 CDS YP_153823.1 56416749 3171706 514140..515027 1 NC_004842.2 conserved family - ribonuclease BN; hypothetical protein 515027 3171706 AM555 Anaplasma marginale str. St. Maries hypothetical protein YP_153823.1 514140 D 234826 CDS YP_153824.1 56416750 3171796 515209..516492 1 NC_004842.2 COG0161 adenosylmethionine-8-amino-7-oxononanoate; similar to ZP_00210585.1; adenosylmethionine-8-amino-7-oxononanoate aminotransferase 516492 bioA 3171796 bioA Anaplasma marginale str. St. Maries adenosylmethionine-8-amino-7-oxononanoate aminotransferase YP_153824.1 515209 D 234826 CDS YP_153825.1 56416751 3171693 516933..517268 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210612.1; hypothetical protein 517268 3171693 AM557 Anaplasma marginale str. St. Maries hypothetical protein YP_153825.1 516933 D 234826 CDS YP_153826.1 56416752 3171102 complement(517430..518242) 1 NC_004842.2 catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA; mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin; dimethyladenosine transferase 518242 ksgA 3171102 ksgA Anaplasma marginale str. St. Maries dimethyladenosine transferase YP_153826.1 517430 R 234826 CDS YP_153827.1 56416753 3171314 518375..519181 1 NC_004842.2 Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate; triosephosphate isomerase 519181 tpiA 3171314 tpiA Anaplasma marginale str. St. Maries triosephosphate isomerase YP_153827.1 518375 D 234826 CDS YP_153828.1 56416754 3171413 519165..520184 1 NC_004842.2 conserved family - cell surface protein; hypothetical protein 520184 3171413 AM560 Anaplasma marginale str. St. Maries hypothetical protein YP_153828.1 519165 D 234826 CDS YP_153829.1 56416755 3171200 520194..521219 1 NC_004842.2 in most organisms, only the N-terminal domain is present in a single polypeptide; in some archaea this domain is fused to a kinase domain; this gene is essential for growth in Escherichia coli and Bacillus subtilis; the secreted glycoprotease from Pasteurella haemolytica showed specificity for O-sialoglycosylated proteins; the Pyrococcus structure shows DNA-binding properties, iron-binding, ATP-binding, and AP endonuclease activity; DNA-binding/iron metalloprotein/AP endonuclease 521219 3171200 AM561 Anaplasma marginale str. St. Maries DNA-binding/iron metalloprotein/AP endonuclease YP_153829.1 520194 D 234826 CDS YP_153830.1 56416756 3171242 complement(521178..521828) 1 NC_004842.2 conserved family - predicted membrane; hypothetical protein 521828 3171242 AM562 Anaplasma marginale str. St. Maries hypothetical protein YP_153830.1 521178 R 234826 CDS YP_153831.1 56416757 3170999 521880..522233 1 NC_004842.2 COG1539 FolB dihydroneopterin aldolase; dihydroneopterin aldolase 522233 folB 3170999 folB Anaplasma marginale str. St. Maries dihydroneopterin aldolase YP_153831.1 521880 D 234826 CDS YP_153832.1 56416758 3171816 522285..523238 1 NC_004842.2 Catalyzes the reversible oxidation of malate to oxaloacetate; malate dehydrogenase 523238 mdh 3171816 mdh Anaplasma marginale str. St. Maries malate dehydrogenase YP_153832.1 522285 D 234826 CDS YP_153833.1 56416759 3170965 complement(523554..524231) 1 NC_004842.2 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 524231 ubiG 3170965 ubiG Anaplasma marginale str. St. Maries 3-demethylubiquinone-9 3-methyltransferase YP_153833.1 523554 R 234826 CDS YP_153834.1 56416760 3171476 524186..524755 1 NC_004842.2 COG0532 translation initiation factor 2 (GTPase); translation initiation factor IF-2 524755 infB 3171476 infB Anaplasma marginale str. St. Maries translation initiation factor IF-2 YP_153834.1 524186 D 234826 CDS YP_153835.1 56416761 3171648 complement(524724..524966) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 524966 3171648 AM569 Anaplasma marginale str. St. Maries hypothetical protein YP_153835.1 524724 R 234826 CDS YP_153836.1 56416762 3171754 525159..525599 1 NC_004842.2 COG0698 ribose 5-phosphate isomerase; similar to ZP_00210562.1; ribose 5-phosphate isomerase 525599 rpiB 3171754 rpiB Anaplasma marginale str. St. Maries ribose 5-phosphate isomerase YP_153836.1 525159 D 234826 CDS YP_153837.1 56416763 3171835 525692..526396 1 NC_004842.2 Involved in ubiquinone biosynthesis; 3-demethylubiquinone-9 3-methyltransferase 526396 ubiG 3171835 ubiG Anaplasma marginale str. St. Maries 3-demethylubiquinone-9 3-methyltransferase YP_153837.1 525692 D 234826 CDS YP_153838.1 56416764 3171842 complement(526497..527003) 1 NC_004842.2 similar to NP_533316.1; O-sialoglycoprotein endopeptidase 527003 gcp 3171842 gcp Anaplasma marginale str. St. Maries O-sialoglycoprotein endopeptidase YP_153838.1 526497 R 234826 CDS YP_153839.1 56416765 3171453 complement(527013..527219) 1 NC_004842.2 conserved hypothetical protein similar to AAL08810.1; hypothetical protein 527219 3171453 AM573 Anaplasma marginale str. St. Maries hypothetical protein YP_153839.1 527013 R 234826 CDS YP_153840.1 56416766 3171806 complement(527461..528138) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210584.1; hypothetical protein 528138 3171806 AM574 Anaplasma marginale str. St. Maries hypothetical protein YP_153840.1 527461 R 234826 CDS YP_153841.1 56416767 3171898 complement(528119..528949) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210584.1; hypothetical protein 528949 3171898 AM576 Anaplasma marginale str. St. Maries hypothetical protein YP_153841.1 528119 R 234826 CDS YP_153842.1 56416768 3171776 complement(528928..529647) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 529647 3171776 AM578 Anaplasma marginale str. St. Maries hypothetical protein YP_153842.1 528928 R 234826 CDS YP_153843.1 56416769 3171788 complement(529698..530105) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210581.1; hypothetical protein 530105 3171788 AM579 Anaplasma marginale str. St. Maries hypothetical protein YP_153843.1 529698 R 234826 CDS YP_153844.1 56416770 3171399 complement(530080..530466) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 530466 3171399 AM580 Anaplasma marginale str. St. Maries hypothetical protein YP_153844.1 530080 R 234826 CDS YP_153845.1 56416771 3171238 complement(530463..531017) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210579.1; hypothetical protein 531017 3171238 AM581 Anaplasma marginale str. St. Maries hypothetical protein YP_153845.1 530463 R 234826 CDS YP_153846.1 56416772 3171109 complement(531026..531367) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 531367 3171109 AM582 Anaplasma marginale str. St. Maries hypothetical protein YP_153846.1 531026 R 234826 CDS YP_153847.1 56416773 3171262 complement(531869..535012) 1 NC_004842.2 proline utilization protein A; multifunctional protein that functions in proline catabolism in the first two enzymatic steps resulting in the conversion of proline to glutamate; in Escherichia coli this protein self regulates transcription via a DNA-binding domain at the N-terminus but the proteins from this group do not and in addition appear to have a truncated C-terminal domain; bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase 535012 putA 3171262 putA Anaplasma marginale str. St. Maries bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase YP_153847.1 531869 R 234826 CDS YP_153848.1 56416774 3171250 535097..536005 1 NC_004842.2 COG1028 FabG dehydrogenases with different specificities (related to short-chain alcohol); similar to NP_360820.1; 3-oxoacyl-ACP reductase 536005 fabG 3171250 fabG Anaplasma marginale str. St. Maries 3-oxoacyl-ACP reductase YP_153848.1 535097 D 234826 CDS YP_153849.1 56416775 3171119 complement(536059..536391) 1 NC_004842.2 conserved family - proline dehydrogenase; hypothetical protein 536391 3171119 AM586 Anaplasma marginale str. St. Maries hypothetical protein YP_153849.1 536059 R 234826 CDS YP_153850.1 56416776 3171753 537408..538310 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 538310 3171753 AM589 Anaplasma marginale str. St. Maries hypothetical protein YP_153850.1 537408 D 234826 CDS YP_153851.1 56416777 3171177 complement(538467..539162) 1 NC_004842.2 COG0797 RlpA lipoproteins; similar to NP_220771.1; rare lipoprotein A 539162 rlpA 3171177 rlpA Anaplasma marginale str. St. Maries rare lipoprotein A YP_153851.1 538467 R 234826 CDS YP_153852.1 56416778 3171163 complement(539361..540191) 1 NC_004842.2 COG0708 XthA exonuclease III; similar to NP_360665.1; exodeoxyribonuclease III 540191 xthA2 3171163 xthA2 Anaplasma marginale str. St. Maries exodeoxyribonuclease III YP_153852.1 539361 R 234826 CDS YP_153853.1 56416779 3171742 complement(540314..541048) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 541048 3171742 AM592 Anaplasma marginale str. St. Maries hypothetical protein YP_153853.1 540314 R 234826 CDS YP_153854.1 56416780 3171444 541381..541500 1 NC_004842.2 COG0257 RpmJ ribosomal protein L36; large subunit ribosomal protein L36 541500 rpmJ 3171444 rpmJ Anaplasma marginale str. St. Maries large subunit ribosomal protein L36 YP_153854.1 541381 D 234826 CDS YP_153855.1 56416781 3171561 541529..541888 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 541888 3171561 AM594 Anaplasma marginale str. St. Maries hypothetical protein YP_153855.1 541529 D 234826 CDS YP_153856.1 56416782 3171602 complement(541901..542551) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 542551 3171602 AM595 Anaplasma marginale str. St. Maries hypothetical protein YP_153856.1 541901 R 234826 CDS YP_153857.1 56416783 3171746 complement(542576..542848) 1 NC_004842.2 involved in the peptidyltransferase reaction during translation; 50S ribosomal protein L27 542848 rpmA 3171746 rpmA Anaplasma marginale str. St. Maries 50S ribosomal protein L27 YP_153857.1 542576 R 234826 CDS YP_153858.2 161544989 3171255 complement(542852..543154) 1 NC_004842.2 COG0261 RplU ribosomal protein L21; 50S ribosomal protein L21 543154 rplU 3171255 rplU Anaplasma marginale str. St. Maries 50S ribosomal protein L21 YP_153858.2 542852 R 234826 CDS YP_153859.1 56416785 3171423 543637..544932 1 NC_004842.2 enolase; catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis; phosphopyruvate hydratase 544932 eno 3171423 eno Anaplasma marginale str. St. Maries phosphopyruvate hydratase YP_153859.1 543637 D 234826 CDS YP_153860.1 56416786 3171722 544934..545980 1 NC_004842.2 essential GTPase; exhibits high exchange rate for GTP/GDP; associates with 50S ribosomal subunit; involved in regulation of chromosomal replication; GTPase ObgE 545980 obgE 3171722 obgE Anaplasma marginale str. St. Maries GTPase ObgE YP_153860.1 544934 D 234826 CDS YP_153861.1 56416787 3171259 545943..546332 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 546332 3171259 AM603 Anaplasma marginale str. St. Maries hypothetical protein YP_153861.1 545943 D 234826 CDS YP_153862.1 56416788 3171309 complement(546503..547378) 1 NC_004842.2 S-adenosyl-methyltransferase; similar to NP_773250.1; S-adenosyl-methyltransferase 547378 mraW 3171309 mraW Anaplasma marginale str. St. Maries S-adenosyl-methyltransferase YP_153862.1 546503 R 234826 CDS YP_153863.1 56416789 3171123 complement(547550..548086) 1 NC_004842.2 COG0212 5-formyltetrahydrofolate cyclo-ligase; similar to ZP_00210813.1; 5-formyltetrahydrofolate cyclo-ligase 548086 ygfA 3171123 ygfA Anaplasma marginale str. St. Maries 5-formyltetrahydrofolate cyclo-ligase YP_153863.1 547550 R 234826 CDS YP_153864.1 56416790 3171400 548370..553613 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 553613 3171400 AM612 Anaplasma marginale str. St. Maries hypothetical protein YP_153864.1 548370 D 234826 CDS YP_153865.1 56416791 3171861 553836..555356 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 555356 3171861 AM613 Anaplasma marginale str. St. Maries hypothetical protein YP_153865.1 553836 D 234826 CDS YP_153866.1 56416792 3171856 complement(555884..556453) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 556453 3171856 AM615 Anaplasma marginale str. St. Maries hypothetical protein YP_153866.1 555884 R 234826 CDS YP_153867.1 56416793 3170968 complement(556586..558397) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 558397 3170968 AM616 Anaplasma marginale str. St. Maries hypothetical protein YP_153867.1 556586 R 234826 CDS YP_153868.1 56416794 3171421 complement(558602..559624) 1 NC_004842.2 COG0492 TrxB thioredoxin reductase; similar to NP_360274.1; thioredoxin reductase 559624 trxB2 3171421 trxB2 Anaplasma marginale str. St. Maries thioredoxin reductase YP_153868.1 558602 R 234826 CDS YP_153869.1 56416795 3171501 complement(559705..561039) 1 NC_004842.2 COG0312 TldD predicted Zn-dependent proteases and their inactivated homologs; similar to NP_774159.1; pmbA protein 561039 pmbA 3171501 pmbA Anaplasma marginale str. St. Maries pmbA protein YP_153869.1 559705 R 234826 CDS YP_153870.1 56416796 3171606 complement(561049..561645) 1 NC_004842.2 COG0302 FolE GTP cyclohydrolase I; GTP cyclohydrolase 561645 folE 3171606 folE Anaplasma marginale str. St. Maries GTP cyclohydrolase YP_153870.1 561049 R 234826 CDS YP_153871.1 56416797 3171384 complement(561652..562515) 1 NC_004842.2 COG0224 AtpG F0F1-type ATP synthase subunit gamma; ATP synthase subunit gamma 562515 atpG 3171384 atpG Anaplasma marginale str. St. Maries ATP synthase subunit gamma YP_153871.1 561652 R 234826 CDS YP_153872.1 56416798 3171138 562810..564006 1 NC_004842.2 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit D 564006 nuoD 3171138 nuoD Anaplasma marginale str. St. Maries NADH dehydrogenase subunit D YP_153872.1 562810 D 234826 CDS YP_153873.1 56416799 3171051 564011..564520 1 NC_004842.2 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit E 564520 nuoE 3171051 nuoE Anaplasma marginale str. St. Maries NADH dehydrogenase subunit E YP_153873.1 564011 D 234826 CDS YP_153874.1 56416800 3171533 564510..565208 1 NC_004842.2 COG0847 DnaQ DNA polymerase III epsilon subunit and related 3'-5' exonucleases; similar to NP_418825.1; DNA polymerase III subunit epsilon 565208 dnaQ 3171533 dnaQ Anaplasma marginale str. St. Maries DNA polymerase III subunit epsilon YP_153874.1 564510 D 234826 CDS YP_153875.1 56416801 3171896 complement(565245..566825) 1 NC_004842.2 conserved hypothetical protein similar to NP_966479.1; hypothetical protein 566825 3171896 AM626 Anaplasma marginale str. St. Maries hypothetical protein YP_153875.1 565245 R 234826 CDS YP_153876.1 56416802 3171854 567191..567829 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 567829 3171854 AM628 Anaplasma marginale str. St. Maries hypothetical protein YP_153876.1 567191 D 234826 CDS YP_153877.1 56416803 3171647 568265..570115 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 570115 3171647 AM629 Anaplasma marginale str. St. Maries hypothetical protein YP_153877.1 568265 D 234826 CDS YP_153878.1 56416804 3171066 complement(570249..570782) 1 NC_004842.2 conserved hypothetical protein similar to NP_966787.1; hypothetical protein 570782 3171066 AM630 Anaplasma marginale str. St. Maries hypothetical protein YP_153878.1 570249 R 234826 CDS YP_153879.1 56416805 3171263 complement(570776..571648) 1 NC_004842.2 COG0568 RpoD DNA-directed RNA polymerase sigma subunits (sigma70/sigma32); similar to NP_421892.1; RNA polymerase sigma-32 factor 571648 rpoH 3171263 rpoH Anaplasma marginale str. St. Maries RNA polymerase sigma-32 factor YP_153879.1 570776 R 234826 CDS YP_153880.1 56416806 3171712 571770..572084 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210576.1; hypothetical protein 572084 3171712 AM632 Anaplasma marginale str. St. Maries hypothetical protein YP_153880.1 571770 D 234826 CDS YP_153881.1 56416807 3171538 572081..572326 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 572326 3171538 AM634 Anaplasma marginale str. St. Maries hypothetical protein YP_153881.1 572081 D 234826 CDS YP_153882.1 56416808 3171745 572766..582350 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 582350 3171745 AM638 Anaplasma marginale str. St. Maries hypothetical protein YP_153882.1 572766 D 234826 CDS YP_153883.1 56416809 3171010 complement(582496..583554) 1 NC_004842.2 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit H 583554 nuoH 3171010 nuoH Anaplasma marginale str. St. Maries NADH dehydrogenase subunit H YP_153883.1 582496 R 234826 CDS YP_153884.1 56416810 3171653 complement(583556..585631) 1 NC_004842.2 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit G 585631 nuoG 3171653 nuoG Anaplasma marginale str. St. Maries NADH dehydrogenase subunit G YP_153884.1 583556 R 234826 CDS YP_153885.1 56416811 3171172 complement(585639..585854) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210543.1; hypothetical protein 585854 3171172 AM642 Anaplasma marginale str. St. Maries hypothetical protein YP_153885.1 585639 R 234826 CDS YP_153886.1 56416812 3171889 complement(586035..588416) 1 NC_004842.2 COG0187 GyrB DNA gyrase (topoisomerase II) B subunit; DNA gyrase subunit B 588416 gyrB2 3171889 gyrB2 Anaplasma marginale str. St. Maries DNA gyrase subunit B YP_153886.1 586035 R 234826 CDS YP_153887.1 56416813 3171107 588750..589355 1 NC_004842.2 COG0163 UbiX 3-polyprenyl-4-hydroxybenzoate decarboxylase; similar to NP_360438.1; 3-octaprenyl-4-hydroxybenzoate carboxy-lyase 589355 ubiX 3171107 ubiX Anaplasma marginale str. St. Maries 3-octaprenyl-4-hydroxybenzoate carboxy-lyase YP_153887.1 588750 D 234826 CDS YP_153888.1 56416814 3171008 complement(589454..589879) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210560.1; hypothetical protein 589879 3171008 AM647 Anaplasma marginale str. St. Maries hypothetical protein YP_153888.1 589454 R 234826 CDS YP_153889.1 56416815 3171100 complement(590379..591602) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 591602 3171100 AM649 Anaplasma marginale str. St. Maries hypothetical protein YP_153889.1 590379 R 234826 CDS YP_153890.1 56416816 3171544 complement(591574..591927) 1 NC_004842.2 COG0633 Fdx ferredoxin; similar to NP_220587.1; ferredoxin [2Fe-2S] adrenodoxin-like precursor adx1 591927 adx1 3171544 adx1 Anaplasma marginale str. St. Maries ferredoxin [2Fe-2S] adrenodoxin-like precursor adx1 YP_153890.1 591574 R 234826 CDS YP_153891.1 56416817 3171306 complement(591953..593761) 1 NC_004842.2 COG0443 DnaK molecular chaperone; heat shock protein 593761 hscA 3171306 hscA Anaplasma marginale str. St. Maries heat shock protein YP_153891.1 591953 R 234826 CDS YP_153892.1 56416818 3171411 complement(593749..594297) 1 NC_004842.2 COG1076 DjlA DnaJ-domain-containing proteins 1; similar to NP_359900.1; chaperone protein 594297 hscB 3171411 hscB Anaplasma marginale str. St. Maries chaperone protein YP_153892.1 593749 R 234826 CDS YP_153893.1 56416819 3171307 complement(594578..594979) 1 NC_004842.2 COG0822 IscU NifU homologs involved in Fe-S cluster formation; scaffold protein 594979 nifU 3171307 nifU Anaplasma marginale str. St. Maries scaffold protein YP_153893.1 594578 R 234826 CDS YP_153894.1 56416820 3171143 complement(594988..596214) 1 NC_004842.2 catalyzes the removal of elemental sulfur from cysteine to produce alanine; involved in NAD biosynthesis; cysteine desulfurase 596214 iscS 3171143 iscS Anaplasma marginale str. St. Maries cysteine desulfurase YP_153894.1 594988 R 234826 CDS YP_153895.1 56416821 3171643 complement(596247..597809) 1 NC_004842.2 conserved family - aminotransferase; hypothetical protein 597809 3171643 AM656 Anaplasma marginale str. St. Maries hypothetical protein YP_153895.1 596247 R 234826 CDS YP_153896.1 56416822 3171677 598007..598711 1 NC_004842.2 conserved family - hydrolase; hypothetical protein 598711 3171677 AM657 Anaplasma marginale str. St. Maries hypothetical protein YP_153896.1 598007 D 234826 CDS YP_153897.1 56416823 3171527 599013..600614 1 NC_004842.2 class I; LysRS1; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri this enzyme charges both tRNA molecules for lysine that exist in this organism (but the tRNALysUUU very poorly) and in the presence of LysRS2 can charge tRNAPyl with lysine; lysyl-tRNA synthetase 600614 lysK 3171527 lysK Anaplasma marginale str. St. Maries lysyl-tRNA synthetase YP_153897.1 599013 D 234826 CDS YP_153898.1 56416824 3171218 600760..601101 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210549.1; hypothetical protein 601101 3171218 AM660 Anaplasma marginale str. St. Maries hypothetical protein YP_153898.1 600760 D 234826 CDS YP_153899.1 56416825 3171862 complement(601147..601890) 1 NC_004842.2 mediates pseudouridylation (positions 38, 39, 40) at the tRNA anticodon region which contributes to the structural stability; tRNA pseudouridine synthase A 601890 truA 3171862 truA Anaplasma marginale str. St. Maries tRNA pseudouridine synthase A YP_153899.1 601147 R 234826 CDS YP_153900.1 56416826 3171391 complement(601887..602783) 1 NC_004842.2 catalyzes the transfer of the carbamoyl moiety from carbamoyl phosphate to L- aspartate in pyrimidine biosynthesis; aspartate carbamoyltransferase catalytic subunit 602783 pyrB 3171391 pyrB Anaplasma marginale str. St. Maries aspartate carbamoyltransferase catalytic subunit YP_153900.1 601887 R 234826 CDS YP_153901.1 56416827 3171083 complement(602946..603605) 1 NC_004842.2 similar to novel fructose-6-phosphate aldolase from Escherichia coli; enzyme from Methanocaldococcus janaschii shows transaldolase activity; translaldolase 603605 3171083 AM664 Anaplasma marginale str. St. Maries translaldolase YP_153901.1 602946 R 234826 CDS YP_153902.1 56416828 3171685 complement(603602..603988) 1 NC_004842.2 COG0355 AtpC F0F1-type ATP synthase epsilon subunit (mitochondrial delta subunit); ATP synthase subunit epsilon 603988 atpC 3171685 atpC Anaplasma marginale str. St. Maries ATP synthase subunit epsilon YP_153902.1 603602 R 234826 CDS YP_153903.1 56416829 3171682 complement(604058..605518) 1 NC_004842.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. The subunit beta is a regulatory subunit; F0F1 ATP synthase subunit beta 605518 atpD 3171682 atpD Anaplasma marginale str. St. Maries F0F1 ATP synthase subunit beta YP_153903.1 604058 R 234826 CDS YP_153904.1 56416830 3171699 605894..607345 1 NC_004842.2 COG2239 MgtE Mg/Co/Ni transporter MgtE (contains CBS domain); magnesium transporter 607345 mgtE 3171699 mgtE Anaplasma marginale str. St. Maries magnesium transporter YP_153904.1 605894 D 234826 CDS YP_153905.1 56416831 3171386 607824..608429 1 NC_004842.2 COG0293 FtsJ methyltransferase involved in cell division; similar to NP_108462.1; cell division protein 608429 ftsJ 3171386 ftsJ Anaplasma marginale str. St. Maries cell division protein YP_153905.1 607824 D 234826 CDS YP_153906.1 56416832 3171197 608913..609782 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 609782 3171197 AM670 Anaplasma marginale str. St. Maries hypothetical protein YP_153906.1 608913 D 234826 CDS YP_153907.1 56416833 3171645 609843..610784 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 610784 3171645 AM671 Anaplasma marginale str. St. Maries hypothetical protein YP_153907.1 609843 D 234826 CDS YP_153908.1 56416834 3171232 611370..612968 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 612968 3171232 AM673 Anaplasma marginale str. St. Maries hypothetical protein YP_153908.1 611370 D 234826 CDS YP_153909.1 56416835 3171496 613573..616785 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 616785 3171496 AM675 Anaplasma marginale str. St. Maries hypothetical protein YP_153909.1 613573 D 234826 CDS YP_153910.1 56416836 3171281 complement(617089..618480) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 618480 3171281 AM676 Anaplasma marginale str. St. Maries hypothetical protein YP_153910.1 617089 R 234826 CDS YP_153911.1 56416837 3171804 complement(618649..620388) 1 NC_004842.2 catalyzes a two-step reaction, first charging an arginine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; class-I aminoacyl-tRNA synthetase; arginyl-tRNA synthetase 620388 argS 3171804 argS Anaplasma marginale str. St. Maries arginyl-tRNA synthetase YP_153911.1 618649 R 234826 CDS YP_153912.1 56416838 3171901 620653..621369 1 NC_004842.2 involved in DNA repair and RecFOR pathway recombination; RecFOR proteins displace ssDNA-binding protein and facilitate the production of RecA-coated ssDNA; DNA repair protein RecO 621369 recO 3171901 recO Anaplasma marginale str. St. Maries DNA repair protein RecO YP_153912.1 620653 D 234826 CDS YP_153913.1 56416839 3171528 621444..622055 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 622055 3171528 AM681 Anaplasma marginale str. St. Maries hypothetical protein YP_153913.1 621444 D 234826 CDS YP_153914.1 56416840 3171148 622067..622273 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 622273 3171148 AM682 Anaplasma marginale str. St. Maries hypothetical protein YP_153914.1 622067 D 234826 CDS YP_153915.1 56416841 3170974 complement(622240..623646) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 623646 3170974 AM683 Anaplasma marginale str. St. Maries hypothetical protein YP_153915.1 622240 R 234826 CDS YP_153916.1 56416842 3171286 complement(623938..627243) 1 NC_004842.2 IleRS; catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile); since isoleucine and other amino acids such as valine are similar, there are additional editing function in this enzyme; one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile); there are two active sites, one for aminoacylation and one for editing; class-I aminoacyl-tRNA synthetase family type 2 subfamily; some organisms carry two different copies of this enzyme; in some organisms, the type 2 subfamily is associated with resistance to the antibiotic pseudomonic acid (mupirocin); isoleucyl-tRNA synthetase 627243 ileS 3171286 ileS Anaplasma marginale str. St. Maries isoleucyl-tRNA synthetase YP_153916.1 623938 R 234826 CDS YP_153917.1 56416843 3171879 627607..628089 1 NC_004842.2 conserved hypothetical protein similar to NP_966995.1; hypothetical protein 628089 3171879 AM685 Anaplasma marginale str. St. Maries hypothetical protein YP_153917.1 627607 D 234826 CDS YP_153918.2 229220790 3171069 628106..628837 1 NC_004842.2 in Escherichia coli RsmE methylates the N3 position of the U1498 base in 16S rRNA; cells lacking this function can grow, but are outcompeted by wild-type; SAM-dependent m(3)U1498 methyltransferase; 16S ribosomal RNA methyltransferase RsmE 628837 3171069 AM686 Anaplasma marginale str. St. Maries 16S ribosomal RNA methyltransferase RsmE YP_153918.2 628106 D 234826 CDS YP_153919.1 56416845 3171708 complement(628841..629110) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 629110 3171708 AM688 Anaplasma marginale str. St. Maries hypothetical protein YP_153919.1 628841 R 234826 CDS YP_153920.1 56416846 3171033 629256..632300 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 632300 3171033 AM689 Anaplasma marginale str. St. Maries hypothetical protein YP_153920.1 629256 D 234826 CDS YP_153921.1 56416847 3171830 complement(632725..633741) 1 NC_004842.2 COG1186 PrfB protein chain release factor B; similar to NP_420681.1; peptide chain release factor 2 633741 prfB 3171830 prfB Anaplasma marginale str. St. Maries peptide chain release factor 2 YP_153921.1 632725 R 234826 CDS YP_153922.1 56416848 3171272 complement(634031..634783) 1 NC_004842.2 conserved hypothetical protein similar to NP_966267.1; hypothetical protein 634783 3171272 AM694 Anaplasma marginale str. St. Maries hypothetical protein YP_153922.1 634031 R 234826 CDS YP_153923.1 56416849 3171356 complement(635162..636631) 1 NC_004842.2 allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases; reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA; aspartyl/glutamyl-tRNA amidotransferase subunit A 636631 gatA 3171356 gatA Anaplasma marginale str. St. Maries aspartyl/glutamyl-tRNA amidotransferase subunit A YP_153923.1 635162 R 234826 CDS YP_153924.1 56416850 3171858 636928..638220 1 NC_004842.2 COG0285 FolC folylpolyglutamate synthase; similar to NP_360416.1; folylpolyglutamate synthase 638220 folC 3171858 folC Anaplasma marginale str. St. Maries folylpolyglutamate synthase YP_153924.1 636928 D 234826 CDS YP_153925.1 56416851 3171518 638378..639289 1 NC_004842.2 transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis; porphobilinogen deaminase 639289 hemC 3171518 hemC Anaplasma marginale str. St. Maries porphobilinogen deaminase YP_153925.1 638378 D 234826 CDS YP_153926.1 56416852 3171591 639264..640163 1 NC_004842.2 catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis; UDP-N-acetylenolpyruvoylglucosamine reductase 640163 murB 3171591 murB Anaplasma marginale str. St. Maries UDP-N-acetylenolpyruvoylglucosamine reductase YP_153926.1 639264 D 234826 CDS YP_153927.1 56416853 3171652 640456..644619 1 NC_004842.2 COG0666 Arp ankyrin repeat proteins; similar to AAP34825.1; ankyrin 644619 ankA 3171652 ankA Anaplasma marginale str. St. Maries ankyrin YP_153927.1 640456 D 234826 CDS YP_153928.1 56416854 3171289 complement(645424..645906) 1 NC_004842.2 Catalyzes the transfer of electrons from NADH to quinone; NADH dehydrogenase subunit I 645906 nuoI 3171289 nuoI Anaplasma marginale str. St. Maries NADH dehydrogenase subunit I YP_153928.1 645424 R 234826 CDS YP_153929.1 56416855 3171521 complement(645922..646641) 1 NC_004842.2 COG0681 LepB signal peptidase I; similar to AAD02938.1; signal peptidase 646641 lepB 3171521 lepB Anaplasma marginale str. St. Maries signal peptidase YP_153929.1 645922 R 234826 CDS YP_153930.1 56416856 3171847 complement(646652..647092) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210598.1; hypothetical protein 647092 3171847 AM709 Anaplasma marginale str. St. Maries hypothetical protein YP_153930.1 646652 R 234826 CDS YP_153931.1 56416857 3171546 647660..658138 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 658138 3171546 AM712 Anaplasma marginale str. St. Maries hypothetical protein YP_153931.1 647660 D 234826 CDS YP_153932.1 56416858 3171190 complement(658530..658817) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 658817 3171190 AM715 Anaplasma marginale str. St. Maries hypothetical protein YP_153932.1 658530 R 234826 CDS YP_153933.1 56416859 3171925 complement(659399..659770) 1 NC_004842.2 other copies include: AM030, AM044, AM065, AM077 AM082, AM210, AM723, AM989, AM1061, AM1149 and AM1253; member of msp2 superfamily; hypothetical protein 659770 orfX 3171925 orfX Anaplasma marginale str. St. Maries hypothetical protein YP_153933.1 659399 R 234826 CDS YP_153934.1 56416860 3171664 662843..663076 1 NC_004842.2 other copies include: AM032, AM046, AM063, AM990 AM1059 and AM1251; member of msp2 superfamily; hypothetical protein 663076 orfY 3171664 orfY Anaplasma marginale str. St. Maries hypothetical protein YP_153934.1 662843 D 234826 CDS YP_153935.1 56416861 3171909 663149..663547 1 NC_004842.2 other copies include: AM030, AM044, AM065, AM077 AM082, AM210, AM717, AM989, AM1061, AM1149 and AM1253; member of msp2 superfamily; hypothetical protein 663547 orfX 3171909 orfX Anaplasma marginale str. St. Maries hypothetical protein YP_153935.1 663149 D 234826 CDS YP_153936.1 56416862 3171339 complement(664842..666701) 1 NC_004842.2 COG1217 TypA predicted membrane GTPase involved in stress response; similar to NP_359986.1; GTP-binding protein 666701 typA 3171339 typA Anaplasma marginale str. St. Maries GTP-binding protein YP_153936.1 664842 R 234826 CDS YP_153937.1 56416863 3171912 complement(666756..669101) 1 NC_004842.2 COG0542 ClpA ATPases with chaperone activity ATP-binding subunit; ATP-dependent Clp protease ATP-binding subunit 669101 clpA 3171912 clpA Anaplasma marginale str. St. Maries ATP-dependent Clp protease ATP-binding subunit YP_153937.1 666756 R 234826 CDS YP_153938.1 56416864 3171111 669205..669918 1 NC_004842.2 COG0861 membrane protein TerC, possibly involved in tellurium resistance; membrane protein 669918 terC 3171111 terC Anaplasma marginale str. St. Maries membrane protein YP_153938.1 669205 D 234826 CDS YP_153939.1 56416865 3171430 complement(670127..670480) 1 NC_004842.2 COG0858 RbfA ribosome-binding factor A; ribosome-binding factor A 670480 rbfA 3171430 rbfA Anaplasma marginale str. St. Maries ribosome-binding factor A YP_153939.1 670127 R 234826 CDS YP_153940.1 56416866 3171936 complement(670477..672975) 1 NC_004842.2 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; translation initiation factor IF-2 672975 infB 3171936 infB Anaplasma marginale str. St. Maries translation initiation factor IF-2 YP_153940.1 670477 R 234826 CDS YP_153941.1 56416867 3171460 complement(672991..674538) 1 NC_004842.2 modifies transcription through interactions with RNA polymerase affecting elongation, readthrough, termination, and antitermination; transcription elongation factor NusA 674538 nusA 3171460 nusA Anaplasma marginale str. St. Maries transcription elongation factor NusA YP_153941.1 672991 R 234826 CDS YP_153942.1 56416868 3171777 complement(675050..678163) 1 NC_004842.2 COG0841 AcrB cation/multidrug efflux pump; similar to NP_220560.1; acriflavin resistance protein D 678163 acrD 3171777 acrD Anaplasma marginale str. St. Maries acriflavin resistance protein D YP_153942.1 675050 R 234826 CDS YP_153943.1 56416869 3171090 complement(678393..679175) 1 NC_004842.2 COG0805 TatC Sec-independent protein secretion pathway component TatC; Sec-independent protein translocase protein 679175 tatC 3171090 tatC Anaplasma marginale str. St. Maries Sec-independent protein translocase protein YP_153943.1 678393 R 234826 CDS YP_153944.1 56416870 3171787 complement(679273..680541) 1 NC_004842.2 catalyzes the conversion of 2C-methyl-D-erythritol 2,4-cyclodiphosphate into 4-hydroxy-3-methyl-2-en-1-yl diphosphate; involved in isoprenoid synthesis; 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase 680541 ispG 3171787 ispG Anaplasma marginale str. St. Maries 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase YP_153944.1 679273 R 234826 CDS YP_153945.1 56416871 3171270 complement(680569..681945) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 681945 3171270 AM742 Anaplasma marginale str. St. Maries hypothetical protein YP_153945.1 680569 R 234826 CDS YP_153946.1 56416872 3170951 complement(682043..683233) 1 NC_004842.2 catalyzes the NADP-dependent rearrangement and reduction of 1-deoxy-D-xylulose-5-phosphate (DXP) to 2-C-methyl-D-erythritol 4-phosphate; 1-deoxy-D-xylulose 5-phosphate reductoisomerase 683233 dxr 3170951 dxr Anaplasma marginale str. St. Maries 1-deoxy-D-xylulose 5-phosphate reductoisomerase YP_153946.1 682043 R 234826 CDS YP_153947.1 56416873 3171778 complement(683247..684692) 1 NC_004842.2 COG1007 NuoN NADH:ubiquinone oxidoreductase subunit 2 (chain N); similar to NP_540062.1; NADH dehydrogenase subunit N 684692 nuoN1 3171778 nuoN1 Anaplasma marginale str. St. Maries NADH dehydrogenase subunit N YP_153947.1 683247 R 234826 CDS YP_153948.1 56416874 3171383 complement(684695..686158) 1 NC_004842.2 COG1008 NuoM NADH:ubiquinone oxidoreductase subunit 4 (chain M); similar to NP_540063.1; NADH dehydrogenase subunit M 686158 nuoM 3171383 nuoM Anaplasma marginale str. St. Maries NADH dehydrogenase subunit M YP_153948.1 684695 R 234826 CDS YP_153949.1 56416875 3171031 complement(686155..688056) 1 NC_004842.2 COG1009 NuoL NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA; similar to NP_697827.1; NADH dehydrogenase subunit L 688056 nuoL 3171031 nuoL Anaplasma marginale str. St. Maries NADH dehydrogenase subunit L YP_153949.1 686155 R 234826 CDS YP_153950.1 56416876 3171555 complement(688124..688450) 1 NC_004842.2 COG0713 NuoK NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K); similar to NP_221141.1; NADH dehydrogenase subunit K 688450 nuoK 3171555 nuoK Anaplasma marginale str. St. Maries NADH dehydrogenase subunit K YP_153950.1 688124 R 234826 CDS YP_153951.1 56416877 3171559 complement(688499..689101) 1 NC_004842.2 COG0839 NuoJ NADH:ubiquinone oxidoreductase subunit 6 (chain J); similar to NP_771548.1; NADH dehydrogenase subunit J 689101 nuoJ 3171559 nuoJ Anaplasma marginale str. St. Maries NADH dehydrogenase subunit J YP_153951.1 688499 R 234826 CDS YP_153952.1 56416878 3171696 complement(689290..690582) 1 NC_004842.2 part of NADH-ubiquinone oxidoreductase complex I; shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain; NuoF is part of the soluble NADH dehydrogenase fragment, which represents the electron input part of NADH dehydrogenase; NADH dehydrogenase I subunit F 690582 nuoF 3171696 nuoF Anaplasma marginale str. St. Maries NADH dehydrogenase I subunit F YP_153952.1 689290 R 234826 CDS YP_153953.1 56416879 3171285 complement(690661..691824) 1 NC_004842.2 COG1250 FadB 3-hydroxyacyl-CoA dehydrogenase; similar to NP_220931.1; 3-hydroxyacyl-COA dehydrogenase 691824 fadB 3171285 fadB Anaplasma marginale str. St. Maries 3-hydroxyacyl-COA dehydrogenase YP_153953.1 690661 R 234826 CDS YP_153954.1 56416880 3171063 complement(691830..692270) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210777.1; hypothetical protein 692270 3171063 AM753 Anaplasma marginale str. St. Maries hypothetical protein YP_153954.1 691830 R 234826 CDS YP_153955.1 56416881 3171877 692470..693387 1 NC_004842.2 COG0324 MiaA tRNA delta(2)-isopentenylpyrophosphate transferase; tRNA isopentenylpyrophosphate transferase 693387 miaA 3171877 miaA Anaplasma marginale str. St. Maries tRNA isopentenylpyrophosphate transferase YP_153955.1 692470 D 234826 CDS YP_153956.1 56416882 3171623 complement(693433..694188) 1 NC_004842.2 conserved family - type IV secretory pathway, component VirB8; hypothetical protein 694188 3171623 AM757 Anaplasma marginale str. St. Maries hypothetical protein YP_153956.1 693433 R 234826 CDS YP_153957.1 56416883 3171155 complement(694352..695701) 1 NC_004842.2 conserved family - RmuC recombination protein; hypothetical protein 695701 3171155 AM758 Anaplasma marginale str. St. Maries hypothetical protein YP_153957.1 694352 R 234826 CDS YP_153958.2 161544988 3171045 695774..697063 1 NC_004842.2 catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; seryl-tRNA synthetase 697063 serS 3171045 serS Anaplasma marginale str. St. Maries seryl-tRNA synthetase YP_153958.2 695774 D 234826 CDS YP_153959.1 56416885 3171355 complement(697239..697784) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 697784 3171355 AM760 Anaplasma marginale str. St. Maries hypothetical protein YP_153959.1 697239 R 234826 CDS YP_153960.1 56416886 3171466 complement(698064..698942) 1 NC_004842.2 catalyzes the conversion of the propionic acid groups of rings I and III to vinyl groups during heme synthesis; coproporphyrinogen III oxidase 698942 hemF 3171466 hemF Anaplasma marginale str. St. Maries coproporphyrinogen III oxidase YP_153960.1 698064 R 234826 CDS YP_153961.1 56416887 3171723 complement(699113..700093) 1 NC_004842.2 catalyzes the phosphorylation of N-acetyl-L-glutamate to form N-acetyl-L-glutamate 5-phosphate; acetylglutamate kinase 700093 agk 3171723 agk Anaplasma marginale str. St. Maries acetylglutamate kinase YP_153961.1 699113 R 234826 CDS YP_153962.1 56416888 3171781 complement(700038..700655) 1 NC_004842.2 binds guanine nucleotides; in Escherichia coli depletion results in defective cell division and filamentation; in Bacillus subtilis this gene is essential; ribosome biogenesis GTP-binding protein YsxC 700655 engB 3171781 engB Anaplasma marginale str. St. Maries ribosome biogenesis GTP-binding protein YsxC YP_153962.1 700038 R 234826 CDS YP_153963.1 56416889 3170972 700982..702061 1 NC_004842.2 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1; this protein is similar to release factor 2; peptide chain release factor 1 702061 prfA 3170972 prfA Anaplasma marginale str. St. Maries peptide chain release factor 1 YP_153963.1 700982 D 234826 CDS YP_153964.1 56416890 3171605 complement(702299..703846) 1 NC_004842.2 similar to NP_220986.1; propionyl-COA carboxylase subunit beta precursor 703846 pccB 3171605 pccB Anaplasma marginale str. St. Maries propionyl-COA carboxylase subunit beta precursor YP_153964.1 702299 R 234826 CDS YP_153965.1 56416891 3171637 complement(704127..704936) 1 NC_004842.2 COG0266 Nei formamidopyrimidine-DNA glycosylase; formamidopyrimidine-DNA glycosylase 704936 fpg 3171637 fpg Anaplasma marginale str. St. Maries formamidopyrimidine-DNA glycosylase YP_153965.1 704127 R 234826 CDS YP_153966.1 56416892 3170941 complement(705141..706598) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 706598 3170941 AM773 Anaplasma marginale str. St. Maries hypothetical protein YP_153966.1 705141 R 234826 CDS YP_153967.1 56416893 3171550 706535..708085 1 NC_004842.2 Charges one glutamine molecule and pairs it to its corresponding RNA trinucleotide during protein translation; glutamyl-tRNA synthetase 708085 gltX 3171550 gltX Anaplasma marginale str. St. Maries glutamyl-tRNA synthetase YP_153967.1 706535 D 234826 CDS YP_153968.1 56416894 3171474 708090..708344 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 708344 3171474 AM776 Anaplasma marginale str. St. Maries hypothetical protein YP_153968.1 708090 D 234826 CDS YP_153969.1 56416895 3171048 complement(708764..710359) 1 NC_004842.2 conserved hypothetical protein similar to NP_966502.1; hypothetical protein 710359 3171048 AM778 Anaplasma marginale str. St. Maries hypothetical protein YP_153969.1 708764 R 234826 CDS YP_153970.1 56416896 3171792 complement(710794..712386) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210829.1; hypothetical protein 712386 3171792 AM779 Anaplasma marginale str. St. Maries hypothetical protein YP_153970.1 710794 R 234826 CDS YP_153971.1 56416897 3171341 complement(712414..714093) 1 NC_004842.2 conserved hypothetical protein similar to NP_966502.1; hypothetical protein 714093 3171341 AM780 Anaplasma marginale str. St. Maries hypothetical protein YP_153971.1 712414 R 234826 CDS YP_153972.1 56416898 3171845 complement(714379..715140) 1 NC_004842.2 COG2857 CYT1 cytochrome C1; similar to EAA25591.1; cytochrome C1, heme protein precursor 715140 petC 3171845 petC Anaplasma marginale str. St. Maries cytochrome C1, heme protein precursor YP_153972.1 714379 R 234826 CDS YP_153973.1 56416899 3171667 complement(715141..716361) 1 NC_004842.2 COG3658 - cytochrome b; cytochrome B 716361 petB 3171667 petB Anaplasma marginale str. St. Maries cytochrome B YP_153973.1 715141 R 234826 CDS YP_153974.1 56416900 3171452 complement(716373..716897) 1 NC_004842.2 COG0723 QcrA Rieske Fe-S protein; similar to EAA25593.1; cytochrome B6-F complex iron-sulfur subunit 716897 petA 3171452 petA Anaplasma marginale str. St. Maries cytochrome B6-F complex iron-sulfur subunit YP_153974.1 716373 R 234826 CDS YP_153975.1 56416901 3171278 complement(717206..717982) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 717982 3171278 AM788 Anaplasma marginale str. St. Maries hypothetical protein YP_153975.1 717206 R 234826 CDS YP_153976.1 56416902 3171282 complement(718246..719049) 1 NC_004842.2 COG1108 ZnuB ABC-type Mn2+/Zn2+ transport systems, permease components; similar to NP_700279.1; zinc ABC transporter permease 719049 znuB 3171282 znuB Anaplasma marginale str. St. Maries zinc ABC transporter permease YP_153976.1 718246 R 234826 CDS YP_153977.1 56416903 3171369 complement(719055..719408) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 719408 3171369 AM790 Anaplasma marginale str. St. Maries hypothetical protein YP_153977.1 719055 R 234826 CDS YP_153978.1 56416904 3171044 complement(719430..720305) 1 NC_004842.2 EF-Ts; functions during elongation stage of protein translation; forms a dimer; associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu; elongation factor Ts 720305 tsf 3171044 tsf Anaplasma marginale str. St. Maries elongation factor Ts YP_153978.1 719430 R 234826 CDS YP_153979.2 161544987 3171326 complement(720341..721324) 1 NC_004842.2 one of the last subunits in the assembly of the 30S subunit; absence of S2 does not inhibit assembly but results in an inactive subunit; 30S ribosomal protein S2 721324 rpsB 3171326 rpsB Anaplasma marginale str. St. Maries 30S ribosomal protein S2 YP_153979.2 720341 R 234826 CDS YP_153980.1 56416906 3171153 complement(721473..722063) 1 NC_004842.2 Maf; overexpression in Bacillus subtilis inhibits septation in the dividing cell; Maf-like protein 722063 maf 3171153 maf Anaplasma marginale str. St. Maries Maf-like protein YP_153980.1 721473 R 234826 CDS YP_153981.1 56416907 3171532 complement(722057..722392) 1 NC_004842.2 COG0424 Maf nucleotide-binding protein implicated in inhibition of septum formation; similar to NP_683835.1; translation initiation factor IF-1 722392 infA 3171532 infA Anaplasma marginale str. St. Maries translation initiation factor IF-1 YP_153981.1 722057 R 234826 CDS YP_153982.1 56416908 3170992 complement(722389..723504) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210840.1; hypothetical protein 723504 3170992 AM796 Anaplasma marginale str. St. Maries hypothetical protein YP_153982.1 722389 R 234826 CDS YP_153983.1 56416909 3171324 complement(723470..724885) 1 NC_004842.2 COG1249 Lpd dihydrolipoamide dehydrogenase/glutathione oxidoreductase and related; dihydrolipoamide dehydrogenase 724885 lpdA 3171324 lpdA Anaplasma marginale str. St. Maries dihydrolipoamide dehydrogenase YP_153983.1 723470 R 234826 CDS YP_153984.1 56416910 3171378 complement(724893..726062) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210842.1; hypothetical protein 726062 3171378 AM798 Anaplasma marginale str. St. Maries hypothetical protein YP_153984.1 724893 R 234826 CDS YP_153985.1 56416911 3171493 726383..727699 1 NC_004842.2 EngA; essential Neisserial GTPase; synchronizes cellular events by interacting with multiple targets with tandem G-domains; overexpression in Escherichia coli suppresses rrmJ mutation; structural analysis of the Thermotoga maritima ortholog shows different nucleotide binding affinities in the two binding domains; GTP-binding protein EngA 727699 engA 3171493 engA Anaplasma marginale str. St. Maries GTP-binding protein EngA YP_153985.1 726383 D 234826 CDS YP_153986.1 56416912 3170957 complement(727807..729384) 1 NC_004842.2 catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate; phosphoglyceromutase 729384 yibO 3170957 yibO Anaplasma marginale str. St. Maries phosphoglyceromutase YP_153986.1 727807 R 234826 CDS YP_153987.2 161544986 3171503 729593..730693 1 NC_004842.2 catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways; forms an octamer composed of four CarAB dimers; carbamoyl phosphate synthase small subunit 730693 carA 3171503 carA Anaplasma marginale str. St. Maries carbamoyl phosphate synthase small subunit YP_153987.2 729593 D 234826 CDS YP_153988.1 56416914 3171942 730871..731899 1 NC_004842.2 catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP); functions in the nonmevalonate isoprenoid biosynthesis pathway; 4-hydroxy-3-methylbut-2-enyl diphosphate reductase 731899 ispH 3171942 ispH Anaplasma marginale str. St. Maries 4-hydroxy-3-methylbut-2-enyl diphosphate reductase YP_153988.1 730871 D 234826 CDS YP_153989.1 56416915 3171654 732101..732544 1 NC_004842.2 COG0756 Dut dUTPase; deoxyuridine 5'triphosphate nucleotidohydrolase 732544 dut 3171654 dut Anaplasma marginale str. St. Maries deoxyuridine 5'triphosphate nucleotidohydrolase YP_153989.1 732101 D 234826 CDS YP_153990.1 56416916 3171850 complement(732591..733982) 1 NC_004842.2 COG0770 MurF UDP-N-acetylmuramyl pentapeptide synthase; UDP-N-acetylmuramyl-tripeptide synthetase 733982 murF 3171850 murF Anaplasma marginale str. St. Maries UDP-N-acetylmuramyl-tripeptide synthetase YP_153990.1 732591 R 234826 CDS YP_153991.1 56416917 3171908 734205..734822 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210848.1; hypothetical protein 734822 3171908 AM809 Anaplasma marginale str. St. Maries hypothetical protein YP_153991.1 734205 D 234826 CDS YP_153992.1 56416918 3171059 complement(734837..739900) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00142380.1; hypothetical protein 739900 3171059 AM810 Anaplasma marginale str. St. Maries hypothetical protein YP_153992.1 734837 R 234826 CDS YP_153993.1 56416919 3171672 complement(739863..743978) 1 NC_004842.2 conserved family - virB6 membrane component; hypothetical protein 743978 3171672 AM811 Anaplasma marginale str. St. Maries hypothetical protein YP_153993.1 739863 R 234826 CDS YP_153994.1 56416920 3171336 complement(743990..747049) 1 NC_004842.2 conserved family - virB6 membrane component; hypothetical protein 747049 3171336 AM812 Anaplasma marginale str. St. Maries hypothetical protein YP_153994.1 743990 R 234826 CDS YP_153995.1 56416921 3171332 complement(747102..749738) 1 NC_004842.2 COG3704 VirB6 type IV secretory pathway, VirB6 components; VirB6 protein 749738 virB6 3171332 virB6 Anaplasma marginale str. St. Maries VirB6 protein YP_153995.1 747102 R 234826 CDS YP_153996.1 56416922 3171241 complement(749731..752139) 1 NC_004842.2 COG3451 VirB4 type IV secretory pathway, VirB4 components; similar to AAM00407.1; other copies include: AM1053; type IV secretion system ATPase VirB4 752139 virB4 3171241 virB4 Anaplasma marginale str. St. Maries type IV secretion system ATPase VirB4 YP_153996.1 749731 R 234826 CDS YP_153997.1 56416923 3171140 complement(752143..752439) 1 NC_004842.2 COG3702 VirB3 type IV secretory pathway, VirB3 components; type IV secretion system protein VirB3 752439 virB3 3171140 virB3 Anaplasma marginale str. St. Maries type IV secretion system protein VirB3 YP_153997.1 752143 R 234826 CDS YP_153998.1 56416924 3170979 complement(752533..753204) 1 NC_004842.2 COG0605 SodA superoxide dismutase; Fe superoxide dismutase 753204 sodB 3170979 sodB Anaplasma marginale str. St. Maries Fe superoxide dismutase YP_153998.1 752533 R 234826 CDS YP_153999.1 56416925 3171247 753368..754753 1 NC_004842.2 COG0581 PstA ABC-type phosphate transport system, permease component; similar to AAM00409.1; phosphate ABC transporter 754753 pstA 3171247 pstA Anaplasma marginale str. St. Maries phosphate ABC transporter YP_153999.1 753368 D 234826 CDS YP_154001.1 56416927 3171651 complement(754976..755917) 1 NC_004842.2 catalyzes the radical-mediated insertion of two sulfur atoms into an ACP ACP bound to an octanoyl group to produce a lipoyl group; lipoyl synthase 755917 lipA 3171651 lipA Anaplasma marginale str. St. Maries lipoyl synthase YP_154001.1 754976 R 234826 CDS YP_154002.1 56416928 3171888 complement(756603..758225) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 758225 3171888 AM821 Anaplasma marginale str. St. Maries hypothetical protein YP_154002.1 756603 R 234826 CDS YP_154003.1 56416929 3171603 complement(758458..762411) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 762411 3171603 AM823 Anaplasma marginale str. St. Maries hypothetical protein YP_154003.1 758458 R 234826 CDS YP_154004.1 56416930 3171022 complement(762503..764491) 1 NC_004842.2 COG1038 PycA pyruvate carboxylase, C-terminal domain/subunit; propionyl-CoA carboxylase subunit alpha 764491 pycA 3171022 pycA Anaplasma marginale str. St. Maries propionyl-CoA carboxylase subunit alpha YP_154004.1 762503 R 234826 CDS YP_154005.1 56416931 3170969 764861..765844 1 NC_004842.2 COG0564 RluA pseudouridylate synthases, 23S RNA-specific; similar to EAA25988.1; sfhb-like protein 765844 sfhB 3170969 sfhB Anaplasma marginale str. St. Maries sfhb-like protein YP_154005.1 764861 D 234826 CDS YP_154006.1 56416932 3171017 complement(765847..766251) 1 NC_004842.2 required for 70S ribosome assembly; 50S ribosomal protein L28 766251 rpmB 3171017 rpmB Anaplasma marginale str. St. Maries 50S ribosomal protein L28 YP_154006.1 765847 R 234826 CDS YP_154007.1 56416933 3171765 complement(766755..768743) 1 NC_004842.2 COG1198 PriA primosomal protein N' (replication factor Y) - superfamily II helicase; similar to NP_360437.1; primosomal protein N' 768743 priA 3171765 priA Anaplasma marginale str. St. Maries primosomal protein N' YP_154007.1 766755 R 234826 CDS YP_154008.1 56416934 3171849 complement(768961..769884) 1 NC_004842.2 conserved hypothetical protein similar to NP_966301.1; hypothetical protein 769884 3171849 AM829 Anaplasma marginale str. St. Maries hypothetical protein YP_154008.1 768961 R 234826 CDS YP_154009.1 56416935 3171353 complement(770010..770813) 1 NC_004842.2 conserved family - uroporphyrinogen-III synthase; hypothetical protein 770813 3171353 AM830 Anaplasma marginale str. St. Maries hypothetical protein YP_154009.1 770010 R 234826 CDS YP_154010.1 56416936 3171657 complement(770910..772622) 1 NC_004842.2 conserved family - aminopeptidase P; hypothetical protein 772622 3171657 AM832 Anaplasma marginale str. St. Maries hypothetical protein YP_154010.1 770910 R 234826 CDS YP_154011.1 56416937 3171802 complement(772749..773276) 1 NC_004842.2 conserved hypothetical protein similar to NP_966046.1; hypothetical protein 773276 3171802 AM833 Anaplasma marginale str. St. Maries hypothetical protein YP_154011.1 772749 R 234826 CDS YP_154012.1 56416938 3171470 complement(773664..774524) 1 NC_004842.2 conserved hypothetical protein similar to NP_966501.1; hypothetical protein 774524 3171470 AM836 Anaplasma marginale str. St. Maries hypothetical protein YP_154012.1 773664 R 234826 CDS YP_154013.1 56416939 3171691 complement(774500..775393) 1 NC_004842.2 Era; Escherichia coli Ras-like protein; Bex; Bacillus Era-complementing segment; essential protein in Escherichia coli that is involved in many cellular processes; GTPase; binds the cell membrane through apparent C-terminal domain; mutants are arrested during the cell cycle; Streptococcus pneumoniae Era binds to RNA and Escherichia coli Era binds 16S rRNA and 30S ribosome; GTP-binding protein Era 775393 era 3171691 era Anaplasma marginale str. St. Maries GTP-binding protein Era YP_154013.1 774500 R 234826 CDS YP_154014.1 56416940 3171372 complement(775488..776843) 1 NC_004842.2 COG0541 Ffh signal recognition particle GTPase; signal recognition particle protein 776843 ffh 3171372 ffh Anaplasma marginale str. St. Maries signal recognition particle protein YP_154014.1 775488 R 234826 CDS YP_154015.1 56416941 3171611 complement(776836..778386) 1 NC_004842.2 subunit D of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; contains an oxidoreductase domain; catalyzes the transfer of electrons from NADH to ubiquinone; monovalent cation/H+ antiporter subunit D 778386 nuoL3 3171611 nuoL3 Anaplasma marginale str. St. Maries monovalent cation/H+ antiporter subunit D YP_154015.1 776836 R 234826 CDS YP_154016.1 56416942 3171642 complement(778461..778937) 1 NC_004842.2 conserved family - oligoketide; hypothetical protein 778937 3171642 AM841 Anaplasma marginale str. St. Maries hypothetical protein YP_154016.1 778461 R 234826 CDS YP_154017.1 56416943 3171733 complement(779164..781101) 1 NC_004842.2 heat shock protein 70; assists in folding of nascent polypeptide chains; refolding of misfolded proteins; utilizes ATPase activity to help fold; co-chaperones are DnaJ and GrpE; multiple copies in some bacteria; molecular chaperone DnaK 781101 dnaK 3171733 dnaK Anaplasma marginale str. St. Maries molecular chaperone DnaK YP_154017.1 779164 R 234826 CDS YP_154018.1 56416944 3171675 complement(781301..783160) 1 NC_004842.2 COG1530 CafA ribonucleases G and E; similar to NP_220641.1; ribonuclease E 783160 rne 3171675 rne Anaplasma marginale str. St. Maries ribonuclease E YP_154018.1 781301 R 234826 CDS YP_154019.1 56416945 3171495 complement(783255..783581) 1 NC_004842.2 subunit C of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit C 783581 3171495 AM846 Anaplasma marginale str. St. Maries monovalent cation/H+ antiporter subunit C YP_154019.1 783255 R 234826 CDS YP_154020.1 56416946 3171328 complement(783668..784144) 1 NC_004842.2 subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit B 784144 3171328 AM847 Anaplasma marginale str. St. Maries monovalent cation/H+ antiporter subunit B YP_154020.1 783668 R 234826 CDS YP_154021.1 56416947 3171208 complement(784101..784670) 1 NC_004842.2 subunit B of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit B 784670 3171208 AM848 Anaplasma marginale str. St. Maries monovalent cation/H+ antiporter subunit B YP_154021.1 784101 R 234826 CDS YP_154022.1 56416948 3171671 complement(784671..784970) 1 NC_004842.2 subunit G of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit G 784970 3171671 AM849 Anaplasma marginale str. St. Maries monovalent cation/H+ antiporter subunit G YP_154022.1 784671 R 234826 CDS YP_154023.1 56416949 3171563 complement(784977..785231) 1 NC_004842.2 subunit F of antiporter complex involved in resistance to high concentrations of Na+, K+, Li+ and/or alkali; monovalent cation/H+ antiporter subunit F 785231 3171563 AM851 Anaplasma marginale str. St. Maries monovalent cation/H+ antiporter subunit F YP_154023.1 784977 R 234826 CDS YP_154024.1 56416950 3171520 complement(785249..787234) 1 NC_004842.2 COG0021 TktA transketolase; similar to NP_698711.1; transketolase 787234 tktA 3171520 tktA Anaplasma marginale str. St. Maries transketolase YP_154024.1 785249 R 234826 CDS YP_154025.1 56416951 3171279 complement(787250..788854) 1 NC_004842.2 conserved family - carboxypeptidase; hypothetical protein 788854 3171279 AM853 Anaplasma marginale str. St. Maries hypothetical protein YP_154025.1 787250 R 234826 CDS YP_154026.1 56416952 3171103 789000..789710 1 NC_004842.2 conserved family - peptidoglycan-associated lipoprotein; hypothetical protein 789710 3171103 AM854 Anaplasma marginale str. St. Maries hypothetical protein YP_154026.1 789000 D 234826 CDS YP_154027.1 56416953 3171522 790004..791341 1 NC_004842.2 catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis; adenylosuccinate synthetase 791341 purA 3171522 purA Anaplasma marginale str. St. Maries adenylosuccinate synthetase YP_154027.1 790004 D 234826 CDS YP_154028.1 56416954 3171344 complement(791345..792331) 1 NC_004842.2 conserved family - GTP-binding protein; hypothetical protein 792331 3171344 AM858 Anaplasma marginale str. St. Maries hypothetical protein YP_154028.1 791345 R 234826 CDS YP_154029.1 56416955 3171234 complement(792369..792863) 1 NC_004842.2 conserved hypothetical protein similar to NP_965963.1; hypothetical protein 792863 3171234 AM859 Anaplasma marginale str. St. Maries hypothetical protein YP_154029.1 792369 R 234826 CDS YP_154030.1 56416956 3171019 complement(792908..794728) 1 NC_004842.2 Catalyzes the rate-limiting step in dNTP synthesis; ribonucleotide-diphosphate reductase subunit alpha 794728 nrdA 3171019 nrdA Anaplasma marginale str. St. Maries ribonucleotide-diphosphate reductase subunit alpha YP_154030.1 792908 R 234826 CDS YP_154031.1 56416957 3171692 795296..796171 1 NC_004842.2 COG0142 IspA geranylgeranyl pyrophosphate synthase; similar to NP_104814.1; geranyltranstransferase (farnesyl-diphosphate synthase) 796171 ispA 3171692 ispA Anaplasma marginale str. St. Maries geranyltranstransferase (farnesyl-diphosphate synthase) YP_154031.1 795296 D 234826 CDS YP_154032.1 56416958 3171564 796220..797116 1 NC_004842.2 conserved hypothetical protein similar to NP_966903.1; hypothetical protein 797116 3171564 AM862 Anaplasma marginale str. St. Maries hypothetical protein YP_154032.1 796220 D 234826 CDS YP_154033.1 56416959 3171812 complement(797146..798135) 1 NC_004842.2 similar to NP_819373.1; thiamine biosynthesis oxidoreductase 798135 thiO 3171812 thiO Anaplasma marginale str. St. Maries thiamine biosynthesis oxidoreductase YP_154033.1 797146 R 234826 CDS YP_154034.1 56416960 3171673 complement(798415..799890) 1 NC_004842.2 unwinds double stranded DNA; replicative DNA helicase 799890 dnaB 3171673 dnaB Anaplasma marginale str. St. Maries replicative DNA helicase YP_154034.1 798415 R 234826 CDS YP_154035.1 56416961 3171670 complement(799944..800618) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210892.1; hypothetical protein 800618 3171670 AM867 Anaplasma marginale str. St. Maries hypothetical protein YP_154035.1 799944 R 234826 CDS YP_154036.1 56416962 3171599 800782..801246 1 NC_004842.2 COG0402 SsnA cytosine deaminase and related metal-dependent hydrolases; similar to NP_542018.1; cytosine deaminase 801246 ssnA 3171599 ssnA Anaplasma marginale str. St. Maries cytosine deaminase YP_154036.1 800782 D 234826 CDS YP_154037.1 56416963 3171592 complement(801378..802346) 1 NC_004842.2 COG0332 FabH 3-oxoacyl-[ACP synthase III; similar to NP_420182.1; 3-oxoacyl-ACP synthase 802346 fabH 3171592 fabH Anaplasma marginale str. St. Maries 3-oxoacyl-ACP synthase YP_154037.1 801378 R 234826 CDS YP_154038.1 56416964 3171506 complement(802346..803389) 1 NC_004842.2 involved in acylation of glycerol-3-phosphate to form 1-acyl-glycerol-3 phosphate for use in phospholipid biosynthesis; functions with PlsY; glycerol-3-phosphate acyltransferase PlsX 803389 plsX 3171506 plsX Anaplasma marginale str. St. Maries glycerol-3-phosphate acyltransferase PlsX YP_154038.1 802346 R 234826 CDS YP_154039.1 56416965 3170942 complement(803389..803565) 1 NC_004842.2 some L32 proteins have zinc finger motifs consisting of CXXC while others do not; 50S ribosomal protein L32 803565 rpmF 3170942 rpmF Anaplasma marginale str. St. Maries 50S ribosomal protein L32 YP_154039.1 803389 R 234826 CDS YP_154040.1 56416966 3171674 803779..805041 1 NC_004842.2 COG0343 Tgt queuine/archaeosine tRNA-ribosyltransferase; queuine tRNA-ribosyltransferase 805041 tgt 3171674 tgt Anaplasma marginale str. St. Maries queuine tRNA-ribosyltransferase YP_154040.1 803779 D 234826 CDS YP_154041.1 56416967 3170944 complement(805237..806061) 1 NC_004842.2 ATP-binding protein; PstABCS is an ATP dependent phosphate uptake system which is responsible for inorganic phosphate uptake during phosphate starvation; phosphate ABC transporter ATP-binding protein 806061 pstB 3170944 pstB Anaplasma marginale str. St. Maries phosphate ABC transporter ATP-binding protein YP_154041.1 805237 R 234826 CDS YP_154042.1 56416968 3171085 complement(806001..806843) 1 NC_004842.2 catalyzes the reduction of 2,3-dihydrodipicolinate to 2,3,4,5-tetrahydrodipicolinate in lysine and diaminopimelate biosynthesis; dihydrodipicolinate reductase 806843 dapB 3171085 dapB Anaplasma marginale str. St. Maries dihydrodipicolinate reductase YP_154042.1 806001 R 234826 CDS YP_154043.1 56416969 3171021 complement(806956..807441) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00142335.1; hypothetical protein 807441 3171021 AM875 Anaplasma marginale str. St. Maries hypothetical protein YP_154043.1 806956 R 234826 CDS YP_154044.1 56416970 3171489 complement(807454..808353) 1 NC_004842.2 UbiA prenyltransferase family catalyzes the transfer of a prenyl group to various acceptors with hydrophobic ring structures in the biosynthesis of respiratory quinones, hemes, chlorophylls, vitamin E, and shikonin; 4-hydroxybenzoate polyprenyltransferase 808353 ubiA 3171489 ubiA Anaplasma marginale str. St. Maries 4-hydroxybenzoate polyprenyltransferase YP_154044.1 807454 R 234826 CDS YP_154045.1 56416971 3170946 complement(808427..809686) 1 NC_004842.2 experimental evidence exists for the production and secretion of this gene product; appendage-associated protein 809686 aaaP 3170946 aaaP Anaplasma marginale str. St. Maries appendage-associated protein YP_154045.1 808427 R 234826 CDS YP_154046.1 56416972 3171053 complement(809841..811124) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 811124 3171053 AM879 Anaplasma marginale str. St. Maries hypothetical protein YP_154046.1 809841 R 234826 CDS YP_154047.1 56416973 3171627 complement(811267..812109) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 812109 3171627 AM880 Anaplasma marginale str. St. Maries hypothetical protein YP_154047.1 811267 R 234826 CDS YP_154048.1 56416974 3171760 812267..812401 1 NC_004842.2 in Escherichia coli transcription of this gene is enhanced by polyamines; 50S ribosomal protein L34 812401 rpmH 3171760 rpmH Anaplasma marginale str. St. Maries 50S ribosomal protein L34 YP_154048.1 812267 D 234826 CDS YP_154049.1 56416975 3171432 812407..812766 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210903.1; hypothetical protein 812766 3171432 AM881 Anaplasma marginale str. St. Maries hypothetical protein YP_154049.1 812407 D 234826 CDS YP_154050.1 56416976 3171863 812779..814098 1 NC_004842.2 conserved family - Na+/alanine symporter; hypothetical protein 814098 3171863 AM882 Anaplasma marginale str. St. Maries hypothetical protein YP_154050.1 812779 D 234826 CDS YP_154051.1 56416977 3171187 complement(814157..816403) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210905.1; hypothetical protein 816403 3171187 AM884 Anaplasma marginale str. St. Maries hypothetical protein YP_154051.1 814157 R 234826 CDS YP_154052.1 56416978 3171554 complement(816685..819048) 1 NC_004842.2 catalyzes a two-step reaction, first charging a phenylalanine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; forms a tetramer of alpha(2)beta(2); binds two magnesium ions per tetramer; type 2 subfamily; phenylalanyl-tRNA synthetase subunit beta 819048 pheT 3171554 pheT Anaplasma marginale str. St. Maries phenylalanyl-tRNA synthetase subunit beta YP_154052.1 816685 R 234826 CDS YP_154053.1 56416979 3170958 complement(819052..819456) 1 NC_004842.2 is a component of the macrolide binding site in the peptidyl transferase center; 50S ribosomal protein L17 819456 rplQ 3170958 rplQ Anaplasma marginale str. St. Maries 50S ribosomal protein L17 YP_154053.1 819052 R 234826 CDS YP_154054.1 56416980 3171181 complement(819497..820597) 1 NC_004842.2 catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the subunit alpha is the first step in the sequential assembly of subunits to form the holoenzyme; DNA-directed RNA polymerase subunit alpha 820597 rpoA 3171181 rpoA Anaplasma marginale str. St. Maries DNA-directed RNA polymerase subunit alpha YP_154054.1 819497 R 234826 CDS YP_154055.2 161544985 3171713 complement(820618..820992) 1 NC_004842.2 located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA; forms part of the Shine-Dalgarno cleft in the 70S ribosome; interacts with S7 and S18 and IF-3; 30S ribosomal protein S11 820992 rpsK 3171713 rpsK Anaplasma marginale str. St. Maries 30S ribosomal protein S11 YP_154055.2 820618 R 234826 CDS YP_154056.1 56416982 3171074 complement(821002..821373) 1 NC_004842.2 located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA; makes contact with the large subunit via RNA-protein interactions and via protein-protein interactions with L5; contacts P-site tRNA; 30S ribosomal protein S13 821373 rpsM 3171074 rpsM Anaplasma marginale str. St. Maries 30S ribosomal protein S13 YP_154056.1 821002 R 234826 CDS YP_154057.1 56416983 3171797 complement(821437..822087) 1 NC_004842.2 COG0563 Adk adenylate kinase and related kinases; adenylate kinase 822087 adk 3171797 adk Anaplasma marginale str. St. Maries adenylate kinase YP_154057.1 821437 R 234826 CDS YP_154058.1 56416984 3171260 complement(822069..823370) 1 NC_004842.2 forms heterotrimeric complex in the membrane; in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG; the SecG subunit is not essential; in bacteria translocation is driven via the SecA ATPase; preprotein translocase subunit SecY 823370 secY 3171260 secY Anaplasma marginale str. St. Maries preprotein translocase subunit SecY YP_154058.1 822069 R 234826 CDS YP_154059.1 56416985 3171933 complement(823394..823834) 1 NC_004842.2 late assembly protein; 50S ribosomal protein L15 823834 rplO 3171933 rplO Anaplasma marginale str. St. Maries 50S ribosomal protein L15 YP_154059.1 823394 R 234826 CDS YP_154060.1 56416986 3171365 complement(823848..824372) 1 NC_004842.2 located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body; contacts S4 and S8; with S4 and S12 plays a role in translational accuracy; mutations in this gene result in spectinomycin resistance; 30S ribosomal protein S5 824372 rpsE 3171365 rpsE Anaplasma marginale str. St. Maries 30S ribosomal protein S5 YP_154060.1 823848 R 234826 CDS YP_154061.1 56416987 3171012 complement(824383..824760) 1 NC_004842.2 binds 5S rRNA along with protein L5 and L25; 50S ribosomal protein L18 824760 rplR 3171012 rplR Anaplasma marginale str. St. Maries 50S ribosomal protein L18 YP_154061.1 824383 R 234826 CDS YP_154062.1 56416988 3171058 complement(824762..825307) 1 NC_004842.2 ribosomal protein L6 appears to have arisen as a result of an ancient gene duplication as based on structural comparison of the Bacillus stearothermophilus protein; RNA-binding appears to be in the C-terminal domain; mutations in the L6 gene confer resistance to aminoglycoside antibiotics such as gentamicin and these occur in truncations of the C-terminal domain; it has been localized to a region between the base of the L7/L12 stalk and the central protuberance; 50S ribosomal protein L6 825307 rplF 3171058 rplF Anaplasma marginale str. St. Maries 50S ribosomal protein L6 YP_154062.1 824762 R 234826 CDS YP_154063.1 56416989 3171439 complement(825319..825717) 1 NC_004842.2 binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; 30S ribosomal protein S8 825717 rpsH 3171439 rpsH Anaplasma marginale str. St. Maries 30S ribosomal protein S8 YP_154063.1 825319 R 234826 CDS YP_154064.1 56416990 3170962 complement(825735..825983) 1 NC_004842.2 COG0199 RpsN ribosomal protein S14; small ribosomal protein S14 825983 rpsN 3170962 rpsN Anaplasma marginale str. St. Maries small ribosomal protein S14 YP_154064.1 825735 R 234826 CDS YP_154065.1 56416991 3171317 complement(826052..826591) 1 NC_004842.2 part of 50S and 5S/L5/L18/L25 subcomplex; contacts 5S rRNA and P site tRNA; forms a bridge to the 30S subunit in the ribosome by binding to S13; 50S ribosomal protein L5 826591 rplE 3171317 rplE Anaplasma marginale str. St. Maries 50S ribosomal protein L5 YP_154065.1 826052 R 234826 CDS YP_154066.1 56416992 3171000 complement(826592..826909) 1 NC_004842.2 assembly initiator protein; binds to 5' end of 23S rRNA and nucleates assembly of the 50S; surrounds polypeptide exit tunnel; 50S ribosomal protein L24 826909 rplX 3171000 rplX Anaplasma marginale str. St. Maries 50S ribosomal protein L24 YP_154066.1 826592 R 234826 CDS YP_154067.1 56416993 3171832 complement(826906..827265) 1 NC_004842.2 binds to the 23S rRNA between the centers for peptidyl transferase and GTPase; 50S ribosomal protein L14 827265 rplN 3171832 rplN Anaplasma marginale str. St. Maries 50S ribosomal protein L14 YP_154067.1 826906 R 234826 CDS YP_154068.1 56416994 3171179 complement(827278..827511) 1 NC_004842.2 primary binding protein; helps mediate assembly; involved in translation fidelity; 30S ribosomal protein S17 827511 rpsQ 3171179 rpsQ Anaplasma marginale str. St. Maries 30S ribosomal protein S17 YP_154068.1 827278 R 234826 CDS YP_154069.1 56416995 3171018 complement(827501..827707) 1 NC_004842.2 one of the stabilizing components for the large ribosomal subunit; 50S ribosomal protein L29 827707 rpmC 3171018 rpmC Anaplasma marginale str. St. Maries 50S ribosomal protein L29 YP_154069.1 827501 R 234826 CDS YP_154070.2 161544984 3171770 complement(827715..828131) 1 NC_004842.2 located in the peptidyl transferase center and may be involved in peptidyl transferase activity; similar to archaeal L10e; 50S ribosomal protein L16 828131 rplP 3171770 rplP Anaplasma marginale str. St. Maries 50S ribosomal protein L16 YP_154070.2 827715 R 234826 CDS YP_154071.1 56416997 3171028 complement(828140..828775) 1 NC_004842.2 forms a complex with S10 and S14; binds the lower part of the 30S subunit head and the mRNA in the complete ribosome to position it for translation; 30S ribosomal protein S3 828775 rpsC 3171028 rpsC Anaplasma marginale str. St. Maries 30S ribosomal protein S3 YP_154071.1 828140 R 234826 CDS YP_154072.1 56416998 3171426 complement(828779..829117) 1 NC_004842.2 binds specifically to 23S rRNA during the early stages of 50S assembly; makes contact with all 6 domains of the 23S rRNA in the assembled 50S subunit and ribosome; mutations in this gene result in erythromycin resistance; located near peptidyl-transferase center; 50S ribosomal protein L22 829117 rplV 3171426 rplV Anaplasma marginale str. St. Maries 50S ribosomal protein L22 YP_154072.1 828779 R 234826 CDS YP_154073.1 56416999 3171726 complement(829121..829402) 1 NC_004842.2 protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA; 30S ribosomal protein S19 829402 rpsS 3171726 rpsS Anaplasma marginale str. St. Maries 30S ribosomal protein S19 YP_154073.1 829121 R 234826 CDS YP_154074.1 56417000 3171922 complement(829408..830241) 1 NC_004842.2 one of the primary rRNA-binding proteins; required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation; 50S ribosomal protein L2 830241 rplB 3171922 rplB Anaplasma marginale str. St. Maries 50S ribosomal protein L2 YP_154074.1 829408 R 234826 CDS YP_154075.1 56417001 3171227 complement(830238..830546) 1 NC_004842.2 binds third domain of 23S rRNA and protein L29; part of exit tunnel; 50S ribosomal protein L23 830546 rplW 3171227 rplW Anaplasma marginale str. St. Maries 50S ribosomal protein L23 YP_154075.1 830238 R 234826 CDS YP_154076.1 56417002 3171811 complement(830521..831147) 1 NC_004842.2 L4 is important during the early stages of 50S assembly; it initially binds near the 5' end of the 23S rRNA; 50S ribosomal protein L4 831147 rplD 3171811 rplD Anaplasma marginale str. St. Maries 50S ribosomal protein L4 YP_154076.1 830521 R 234826 CDS YP_154077.1 56417003 3171188 complement(831165..831863) 1 NC_004842.2 binds directly near the 3' end of the 23S rRNA, where it nucleates assembly of the 50S subunit; essential for peptidyltransferase activity; mutations in this gene confer resistance to tiamulin; 50S ribosomal protein L3 831863 rplC 3171188 rplC Anaplasma marginale str. St. Maries 50S ribosomal protein L3 YP_154077.1 831165 R 234826 CDS YP_154078.1 56417004 3171590 complement(831865..832182) 1 NC_004842.2 NusE; involved in assembly of the 30S subunit; in the ribosome, this protein is involved in the binding of tRNA; in Escherichia coli this protein was also found to be involved in transcription antitermination; NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination; binding of NusB/S10 to boxA nucleates assembly of the antitermination complex; 30S ribosomal protein S10 832182 rpsJ 3171590 rpsJ Anaplasma marginale str. St. Maries 30S ribosomal protein S10 YP_154078.1 831865 R 234826 CDS YP_154079.1 56417005 3171810 complement(832189..833370) 1 NC_004842.2 EF-Tu; promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis; when the tRNA anticodon matches the mRNA codon, GTP hydrolysis results; the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts; many prokaryotes have two copies of the gene encoding EF-Tu; elongation factor Tu 833370 tuf 3171810 tuf Anaplasma marginale str. St. Maries elongation factor Tu YP_154079.1 832189 R 234826 CDS YP_154080.1 56417006 3171530 833746..834531 1 NC_004842.2 conserved family - tRNA/rRNA methyltransferase; hypothetical protein 834531 3171530 AM915 Anaplasma marginale str. St. Maries hypothetical protein YP_154080.1 833746 D 234826 CDS YP_154081.1 56417007 3171027 834518..835195 1 NC_004842.2 COG0283 Cmk cytidylate kinase; cytidylate kinase 835195 cmk 3171027 cmk Anaplasma marginale str. St. Maries cytidylate kinase YP_154081.1 834518 D 234826 CDS YP_154082.1 56417008 3171487 835260..836939 1 NC_004842.2 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit; autoregulates expression via a C-terminal domain; in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats; the S1 nucleic acid-binding domain is found associated with other proteins; 30S ribosomal protein S1 836939 rpsA 3171487 rpsA Anaplasma marginale str. St. Maries 30S ribosomal protein S1 YP_154082.1 835260 D 234826 CDS YP_154083.1 56417009 3171569 836943..837824 1 NC_004842.2 COG0616 SppA periplasmic serine proteases (ClpP class); similar to NP_104359.1; protease IV 837824 sppA 3171569 sppA Anaplasma marginale str. St. Maries protease IV YP_154083.1 836943 D 234826 CDS YP_154084.1 56417010 3171024 838073..838570 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 838570 3171024 AM919 Anaplasma marginale str. St. Maries hypothetical protein YP_154084.1 838073 D 234826 CDS YP_154085.1 56417011 3171676 838571..839008 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 839008 3171676 AM920 Anaplasma marginale str. St. Maries hypothetical protein YP_154085.1 838571 D 234826 CDS YP_154086.1 56417012 3171154 839324..840277 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 840277 3171154 AM921 Anaplasma marginale str. St. Maries hypothetical protein YP_154086.1 839324 D 234826 CDS YP_154087.1 56417013 3171414 840581..841633 1 NC_004842.2 protoheme ferro-lyase; catalyzes the insertion of a ferrous ion into protoporphyrin IX to form protoheme; involved in protoheme biosynthesis; in some organisms this protein is membrane-associated while in others it is cytosolic; ferrochelatase 841633 hemH 3171414 hemH Anaplasma marginale str. St. Maries ferrochelatase YP_154087.1 840581 D 234826 CDS YP_154088.1 56417014 3171661 complement(841636..842700) 1 NC_004842.2 conserved family - ATPase; hypothetical protein 842700 3171661 AM923 Anaplasma marginale str. St. Maries hypothetical protein YP_154088.1 841636 R 234826 CDS YP_154089.1 56417015 3171531 complement(842956..843282) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210943.1; hypothetical protein 843282 3171531 AM924 Anaplasma marginale str. St. Maries hypothetical protein YP_154089.1 842956 R 234826 CDS YP_154090.1 56417016 3171167 complement(843819..844742) 1 NC_004842.2 COG0330 HflC membrane protease subunits stomatin/prohibitin homologs; similar to NP_815489.1; second copy is ORF AM1064; HFLK protein 844742 hflK 3171167 hflK Anaplasma marginale str. St. Maries HFLK protein YP_154090.1 843819 R 234826 CDS YP_154091.1 56417017 3171921 complement(844805..845653) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 845653 3171921 AM926 Anaplasma marginale str. St. Maries hypothetical protein YP_154091.1 844805 R 234826 CDS YP_154092.1 56417018 3171747 845751..848354 1 NC_004842.2 conserved family - ATP-dependent nuclease; hypothetical protein 848354 3171747 AM927 Anaplasma marginale str. St. Maries hypothetical protein YP_154092.1 845751 D 234826 CDS YP_154093.1 56417019 3171311 complement(848679..849662) 1 NC_004842.2 COG0604 Qor NADPH:quinone reductase and related Zn-dependent oxidoreductases; similar to NP_102293.1; quinone oxidoreductase 849662 qor 3171311 qor Anaplasma marginale str. St. Maries quinone oxidoreductase YP_154093.1 848679 R 234826 CDS YP_154094.1 56417020 3171467 complement(849768..852170) 1 NC_004842.2 conserved family - alkaline protease secretion ATP-binding protein; hypothetical protein 852170 3171467 AM929 Anaplasma marginale str. St. Maries hypothetical protein YP_154094.1 849768 R 234826 CDS YP_154095.1 56417021 3171211 852504..853310 1 NC_004842.2 COG0294 FolP dihydropteroate synthase and related enzymes; similar to NP_279484.1; dihydropteroate synthase 853310 folP 3171211 folP Anaplasma marginale str. St. Maries dihydropteroate synthase YP_154095.1 852504 D 234826 CDS YP_154096.1 56417022 3171824 853769..857077 1 NC_004842.2 four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate; CarB is responsible for the amidotransferase activity; carbamoyl phosphate synthase large subunit 857077 carB 3171824 carB Anaplasma marginale str. St. Maries carbamoyl phosphate synthase large subunit YP_154096.1 853769 D 234826 CDS YP_154097.1 56417023 3171084 complement(858293..858685) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 858685 3171084 AM936 Anaplasma marginale str. St. Maries hypothetical protein YP_154097.1 858293 R 234826 CDS YP_154098.1 56417024 3171020 complement(858850..860238) 1 NC_004842.2 class II family (does not require metal); tetrameric enzyme; fumarase C; reversibly converts (S)-malate to fumarate and water; functions in the TCA cycle; fumarate hydratase 860238 fumC 3171020 fumC Anaplasma marginale str. St. Maries fumarate hydratase YP_154098.1 858850 R 234826 CDS YP_154099.1 56417025 3171473 860408..861058 1 NC_004842.2 conserved family - pantothenate metabolism flavoprotein; hypothetical protein 861058 3171473 AM938 Anaplasma marginale str. St. Maries hypothetical protein YP_154099.1 860408 D 234826 CDS YP_154100.1 56417026 3171338 861059..862423 1 NC_004842.2 dihydroorotase and related cyclic amidohydrolases; similar to ZP_00210957.1; dihydroorotase 862423 pyrC 3171338 pyrC Anaplasma marginale str. St. Maries dihydroorotase YP_154100.1 861059 D 234826 CDS YP_154101.1 56417027 3171422 complement(862557..863915) 1 NC_004842.2 COG1109 CpsG phosphomannomutase; similar to NP_698675.1; phosphoglucosamine mutase 863915 glmM 3171422 glmM Anaplasma marginale str. St. Maries phosphoglucosamine mutase YP_154101.1 862557 R 234826 CDS YP_154102.1 56417028 3170953 complement(863952..864596) 1 NC_004842.2 lipoyl-[acyl-carrier protein]-protein-N-lipoyltransferse; lipoate-protein ligase B; transfers lipoate to apolipoproteins; involved in lipoate metabolism; lipoyltransferase 864596 lipB 3170953 lipB Anaplasma marginale str. St. Maries lipoyltransferase YP_154102.1 863952 R 234826 CDS YP_154103.1 56417029 3171106 complement(864687..865379) 1 NC_004842.2 COG2003 RadC DNA repair proteins; DNA repair protein 865379 radC 3171106 radC Anaplasma marginale str. St. Maries DNA repair protein YP_154103.1 864687 R 234826 CDS YP_154104.2 161544983 3171906 865600..865884 1 NC_004842.2 10 kDa chaperonin; Cpn10; GroES; forms homoheptameric ring; binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it; folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES; release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring; co-chaperonin GroES 865884 groES 3171906 groES Anaplasma marginale str. St. Maries co-chaperonin GroES YP_154104.2 865600 D 234826 CDS YP_154105.1 56417031 3171347 865932..867581 1 NC_004842.2 60 kDa chaperone family; promotes refolding of misfolded polypeptides especially under stressful conditions; forms two stacked rings of heptamers to form a barrel-shaped 14mer; ends can be capped by GroES; misfolded proteins enter the barrel where they are refolded when GroES binds; many bacteria have multiple copies of the groEL gene which are active under different environmental conditions; the B.japonicum protein in this cluster is expressed constitutively; in Rhodobacter, Corynebacterium and Rhizobium this protein is essential for growth; chaperonin GroEL 867581 groEL 3171347 groEL Anaplasma marginale str. St. Maries chaperonin GroEL YP_154105.1 865932 D 234826 CDS YP_154106.1 56417032 3171406 complement(868196..868927) 1 NC_004842.2 conserved family - oxidoreductase short-chain dehydrogenase; hypothetical protein 868927 3171406 AM947 Anaplasma marginale str. St. Maries hypothetical protein YP_154106.1 868196 R 234826 CDS YP_154107.1 56417033 3171491 869149..871767 1 NC_004842.2 COG0542 ATPases with chaperone activity ATP-binding subunit; ATP-dependent Clp protease ATP-binding subunit 871767 clpB 3171491 clpB Anaplasma marginale str. St. Maries ATP-dependent Clp protease ATP-binding subunit YP_154107.1 869149 D 234826 CDS YP_154108.1 56417034 3171589 complement(871879..873540) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 873540 3171589 AM950 Anaplasma marginale str. St. Maries hypothetical protein YP_154108.1 871879 R 234826 CDS YP_154109.1 56417035 3171070 complement(873771..874763) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 874763 3171070 AM952 Anaplasma marginale str. St. Maries hypothetical protein YP_154109.1 873771 R 234826 CDS YP_154110.1 56417036 3171927 complement(874868..875608) 1 NC_004842.2 conserved family - dioxygenase; hypothetical protein 875608 3171927 AM953 Anaplasma marginale str. St. Maries hypothetical protein YP_154110.1 874868 R 234826 CDS YP_154111.1 56417037 3170985 875813..876211 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 876211 3170985 AM955 Anaplasma marginale str. St. Maries hypothetical protein YP_154111.1 875813 D 234826 CDS YP_154112.1 56417038 3171893 876183..877787 1 NC_004842.2 catalyzes the removal of N-terminal amino acids preferably leucine from various peptides; leucyl aminopeptidase 877787 pepA 3171893 pepA Anaplasma marginale str. St. Maries leucyl aminopeptidase YP_154112.1 876183 D 234826 CDS YP_154113.1 56417039 3170991 877803..878447 1 NC_004842.2 conserved family - phosphoribosylglycinamide formyltransferase; hypothetical protein 878447 3170991 AM957 Anaplasma marginale str. St. Maries hypothetical protein YP_154113.1 877803 D 234826 CDS YP_154114.1 56417040 3170954 complement(878594..880069) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 880069 3170954 AM959 Anaplasma marginale str. St. Maries hypothetical protein YP_154114.1 878594 R 234826 CDS YP_154115.1 56417041 3171298 complement(880211..880993) 1 NC_004842.2 COG0046 PurL phosphoribosylformylglycinamidine (synthase, synthetase domain; similar to NP_868461.1; phosphoribosylformylglycinamidine synthase 880993 purQ 3171298 purQ Anaplasma marginale str. St. Maries phosphoribosylformylglycinamidine synthase YP_154115.1 880211 R 234826 CDS YP_154116.1 56417042 3171193 881074..882987 1 NC_004842.2 GidA; glucose-inhibited cell division protein A; involved in the 5-carboxymethylaminomethyl modification (mnm(5)s(2)U) of the wobble uridine base in some tRNAs; tRNA uridine 5-carboxymethylaminomethyl modification protein GidA 882987 gidA 3171193 gidA Anaplasma marginale str. St. Maries tRNA uridine 5-carboxymethylaminomethyl modification protein GidA YP_154116.1 881074 D 234826 CDS YP_154117.1 56417043 3171566 complement(883300..884265) 1 NC_004842.2 type II fructose 1,6-bisphosphatae; in Escherichia coli this protein forms a dimer and binds manganese; fructose 1,6-bisphosphatase II 884265 glpX 3171566 glpX Anaplasma marginale str. St. Maries fructose 1,6-bisphosphatase II YP_154117.1 883300 R 234826 CDS YP_154118.1 56417044 3171060 884352..885053 1 NC_004842.2 conserved hypothetical protein similar to NP_252313.1; hypothetical protein 885053 3171060 AM965 Anaplasma marginale str. St. Maries hypothetical protein YP_154118.1 884352 D 234826 CDS YP_154119.1 56417045 3171515 885213..885668 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210971.1; hypothetical protein 885668 3171515 AM967 Anaplasma marginale str. St. Maries hypothetical protein YP_154119.1 885213 D 234826 CDS YP_154120.1 56417046 3171613 885769..886053 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 886053 3171613 AM968 Anaplasma marginale str. St. Maries hypothetical protein YP_154120.1 885769 D 234826 CDS YP_154121.1 56417047 3171351 886040..887014 1 NC_004842.2 COG0502 BioB biotin synthase and related enzymes; similar to NP_415296.1; biotin synthase 887014 bioB 3171351 bioB Anaplasma marginale str. St. Maries biotin synthase YP_154121.1 886040 D 234826 CDS YP_154122.1 56417048 3171381 887742..890792 1 NC_004842.2 COG0046 PurL phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain; phosphoribosylformylglycinamidine synthase 890792 purL 3171381 purL Anaplasma marginale str. St. Maries phosphoribosylformylglycinamidine synthase YP_154122.1 887742 D 234826 CDS YP_154123.1 56417049 3171887 890823..891029 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 891029 3171887 AM974 Anaplasma marginale str. St. Maries hypothetical protein YP_154123.1 890823 D 234826 CDS YP_154124.1 56417050 3171457 891166..891870 1 NC_004842.2 conserved family - 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase; hypothetical protein 891870 3171457 AM975 Anaplasma marginale str. St. Maries hypothetical protein YP_154124.1 891166 D 234826 CDS YP_154125.1 56417051 3171221 complement(891926..892141) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 892141 3171221 AM976 Anaplasma marginale str. St. Maries hypothetical protein YP_154125.1 891926 R 234826 CDS YP_154126.1 56417052 3171441 complement(892150..892698) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210976.1; hypothetical protein 892698 3171441 AM977 Anaplasma marginale str. St. Maries hypothetical protein YP_154126.1 892150 R 234826 CDS YP_154127.1 56417053 3171903 complement(892797..894077) 1 NC_004842.2 conserved hypothetical protein similar to NP_420685.1; hypothetical protein 894077 3171903 AM979 Anaplasma marginale str. St. Maries hypothetical protein YP_154127.1 892797 R 234826 CDS YP_154128.1 56417054 3171046 894252..894620 1 NC_004842.2 conserved family - uncharacterized homolog of plant Iojap protein; hypothetical protein 894620 3171046 AM980 Anaplasma marginale str. St. Maries hypothetical protein YP_154128.1 894252 D 234826 CDS YP_154129.1 56417055 3171609 894865..895755 1 NC_004842.2 conserved hypothetical protein similar to NP_965909.1; hypothetical protein 895755 3171609 AM981 Anaplasma marginale str. St. Maries hypothetical protein YP_154129.1 894865 D 234826 CDS YP_154130.1 56417056 3171826 complement(895993..896646) 1 NC_004842.2 conserved hypothetical protein similar to NP_966750.1; hypothetical protein 896646 3171826 AM982 Anaplasma marginale str. St. Maries hypothetical protein YP_154130.1 895993 R 234826 CDS YP_154131.1 56417057 3171880 896760..897815 1 NC_004842.2 catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis; phosphoribosylaminoimidazole synthetase 897815 purM 3171880 purM Anaplasma marginale str. St. Maries phosphoribosylaminoimidazole synthetase YP_154131.1 896760 D 234826 CDS YP_154132.1 56417058 3171434 complement(897807..898757) 1 NC_004842.2 COG0582 XerC integrase; similar to NP_698893.1; integrase/recombinase ripx 898757 xerC 3171434 xerC Anaplasma marginale str. St. Maries integrase/recombinase ripx YP_154132.1 897807 R 234826 CDS YP_154133.1 56417059 3171794 898926..900095 1 NC_004842.2 COG0240 GpsA glycerol 3-phosphate dehydrogenase; gylcerol-3-phosphate dehydrogenase 900095 gpsA 3171794 gpsA Anaplasma marginale str. St. Maries gylcerol-3-phosphate dehydrogenase YP_154133.1 898926 D 234826 CDS YP_154134.1 56417060 3171905 900092..900547 1 NC_004842.2 member of msp2 superfamily; outer membrane protein 15 900547 omp15 3171905 omp15 Anaplasma marginale str. St. Maries outer membrane protein 15 YP_154134.1 900092 D 234826 CDS YP_154135.1 56417061 3170982 complement(900783..901157) 1 NC_004842.2 other copies include: AM030, AM044, AM065, AM077 AM082, AM210, AM717, AM723, AM1061, AM1149 and AM1253; member of msp2 superfamily; hypothetical protein 901157 orfX 3170982 orfX Anaplasma marginale str. St. Maries hypothetical protein YP_154135.1 900783 R 234826 CDS YP_154136.1 56417062 3171402 complement(901157..901468) 1 NC_004842.2 other copies include: AM032, AM046, AM063, AM721 AM1059 and AM1251; member of msp2 superfamily; hypothetical protein 901468 orfY 3171402 orfY Anaplasma marginale str. St. Maries hypothetical protein YP_154136.1 901157 R 234826 CDS YP_154137.1 56417063 3171483 complement(901852..903234) 1 NC_004842.2 An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes; transcription termination factor Rho 903234 rho 3171483 rho Anaplasma marginale str. St. Maries transcription termination factor Rho YP_154137.1 901852 R 234826 CDS YP_154138.1 56417064 3171065 complement(903504..903842) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 903842 3171065 AM997 Anaplasma marginale str. St. Maries hypothetical protein YP_154138.1 903504 R 234826 CDS YP_154139.1 56417065 3171721 904024..904593 1 NC_004842.2 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease peptidase subunit 904593 hslV 3171721 hslV Anaplasma marginale str. St. Maries ATP-dependent protease peptidase subunit YP_154139.1 904024 D 234826 CDS YP_154140.1 56417066 3171389 904590..906038 1 NC_004842.2 heat shock protein involved in degradation of misfolded proteins; ATP-dependent protease ATP-binding subunit HslU 906038 hslU 3171389 hslU Anaplasma marginale str. St. Maries ATP-dependent protease ATP-binding subunit HslU YP_154140.1 904590 D 234826 CDS YP_154141.1 56417067 3171144 906042..906785 1 NC_004842.2 COG2226 UbiE methylase involved in ubiquinone/menaquinone biosynthesis; similar to NP_700228.1; ubiquinone/menaquinone biosynthesis methyltransferase 906785 ubiE 3171144 ubiE Anaplasma marginale str. St. Maries ubiquinone/menaquinone biosynthesis methyltransferase YP_154141.1 906042 D 234826 CDS YP_154142.1 56417068 3171113 complement(906786..908153) 1 NC_004842.2 COG0143 MetG methionyl-tRNA synthetase; similar to NP_360683.1; methionyl-tRNA synthetase 908153 metS 3171113 metS Anaplasma marginale str. St. Maries methionyl-tRNA synthetase YP_154142.1 906786 R 234826 CDS YP_154143.1 56417069 3171456 908599..909837 1 NC_004842.2 catalyzes the formation of 4-phospho-L-aspartate from L-aspartate and ATP, in Bacillus, lysine sensitive; regulated by response to starvation.; aspartate kinase 909837 lysC 3171456 lysC Anaplasma marginale str. St. Maries aspartate kinase YP_154143.1 908599 D 234826 CDS YP_154144.1 56417070 3171739 complement(909871..910086) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 910086 3171739 AM1006 Anaplasma marginale str. St. Maries hypothetical protein YP_154144.1 909871 R 234826 CDS YP_154145.1 56417071 3171940 910094..910924 1 NC_004842.2 COG1622 CyoA Heme/copper-type cytochrome/quinol oxidases, subunit 2; cytochrome C oxidase subunit II 910924 coxB 3171940 coxB Anaplasma marginale str. St. Maries cytochrome C oxidase subunit II YP_154145.1 910094 D 234826 CDS YP_154146.1 56417072 3171121 911021..912586 1 NC_004842.2 COG0843 CyoB Heme/copper-type cytochrome/quinol oxidases, subunit 1; cytochrome C oxidase subunit I 912586 coxA 3171121 coxA Anaplasma marginale str. St. Maries cytochrome C oxidase subunit I YP_154146.1 911021 D 234826 CDS YP_154147.1 56417073 3171191 912596..913501 1 NC_004842.2 converts protoheme IX and farnesyl diphosphate to heme O; protoheme IX farnesyltransferase 913501 ctaB 3171191 ctaB Anaplasma marginale str. St. Maries protoheme IX farnesyltransferase YP_154147.1 912596 D 234826 CDS YP_154148.1 56417074 3171836 complement(913554..914480) 1 NC_004842.2 conserved family - DNA uptake lipoprotein; hypothetical protein 914480 3171836 AM1010 Anaplasma marginale str. St. Maries hypothetical protein YP_154148.1 913554 R 234826 CDS YP_154149.1 56417075 3171271 914624..915886 1 NC_004842.2 catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis; phosphoribosylamine--glycine ligase 915886 purD 3171271 purD Anaplasma marginale str. St. Maries phosphoribosylamine--glycine ligase YP_154149.1 914624 D 234826 CDS YP_154150.1 56417076 3171479 915917..916423 1 NC_004842.2 COG1862 YajC preprotein translocase subunit YajC; preprotein translocase subunit 916423 yajC 3171479 yajC Anaplasma marginale str. St. Maries preprotein translocase subunit YP_154150.1 915917 D 234826 CDS YP_154151.1 56417077 3170947 916492..918318 1 NC_004842.2 COG0449 GlmS glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar; similar to NP_771247.1; glucosamine--fructose-6-phosphate aminotransferase 918318 glmS 3170947 glmS Anaplasma marginale str. St. Maries glucosamine--fructose-6-phosphate aminotransferase YP_154151.1 916492 D 234826 CDS YP_154152.1 56417078 3171846 complement(918685..919824) 1 NC_004842.2 COG0592 DnaN DNA polymerase sliding clamp subunit (PCNA homolog); DNA polymerase III subunit beta 919824 dnaN 3171846 dnaN Anaplasma marginale str. St. Maries DNA polymerase III subunit beta YP_154152.1 918685 R 234826 CDS YP_154153.1 56417079 3171891 complement(920045..920659) 1 NC_004842.2 COG0349 Rnd ribonuclease D; other copies include: AM151; ribonuclease D 920659 rnd 3171891 rnd Anaplasma marginale str. St. Maries ribonuclease D YP_154153.1 920045 R 234826 CDS YP_154154.1 56417080 3171156 complement(920724..921596) 1 NC_004842.2 COG0745 OmpR response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding; transcriptional activator protein 921596 czcR 3171156 czcR Anaplasma marginale str. St. Maries transcriptional activator protein YP_154154.1 920724 R 234826 CDS YP_154155.1 56417081 3171584 complement(921897..922544) 1 NC_004842.2 conserved family - transcriptional regulator; hypothetical protein 922544 3171584 AM1018 Anaplasma marginale str. St. Maries hypothetical protein YP_154155.1 921897 R 234826 CDS YP_154156.1 56417082 3171884 complement(923388..923915) 1 NC_004842.2 COG0221 Ppa inorganic pyrophosphatase; inorganic phosphatase protein 923915 ppa 3171884 ppa Anaplasma marginale str. St. Maries inorganic phosphatase protein YP_154156.1 923388 R 234826 CDS YP_154157.1 56417083 3171178 complement(924979..925203) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 925203 3171178 AM1021 Anaplasma marginale str. St. Maries hypothetical protein YP_154157.1 924979 R 234826 CDS YP_154158.1 56417084 3170995 complement(925139..925600) 1 NC_004842.2 forms a direct contact with the tRNA during translation; 30S ribosomal protein S9 925600 rpsI 3170995 rpsI Anaplasma marginale str. St. Maries 30S ribosomal protein S9 YP_154158.1 925139 R 234826 CDS YP_154159.1 56417085 3171720 complement(925572..926084) 1 NC_004842.2 in Escherichia coli this protein is one of the earliest assembly proteins in the large subunit; 50S ribosomal protein L13 926084 rplM 3171720 rplM Anaplasma marginale str. St. Maries 50S ribosomal protein L13 YP_154159.1 925572 R 234826 CDS YP_154160.1 56417086 3171364 926120..927517 1 NC_004842.2 COG1538 TolC outer membrane protein; outer membrane protein 927517 tolC 3171364 tolC Anaplasma marginale str. St. Maries outer membrane protein YP_154160.1 926120 D 234826 CDS YP_154161.1 56417087 3171568 927536..928129 1 NC_004842.2 conserved hypothetical protein similar to NP_965897.1; hypothetical protein 928129 3171568 AM1025 Anaplasma marginale str. St. Maries hypothetical protein YP_154161.1 927536 D 234826 CDS YP_154162.1 56417088 3171782 complement(928257..929288) 1 NC_004842.2 conserved family - ATPase involved in chromosome partitioning; hypothetical protein 929288 3171782 AM1027 Anaplasma marginale str. St. Maries hypothetical protein YP_154162.1 928257 R 234826 CDS YP_154163.1 56417089 3171081 929392..930171 1 NC_004842.2 COG0462 PrsA phosphoribosylpyrophosphate synthetase; similar to NP_797118.1; phosphoribosylpyrophosphate synthetase 930171 prsA 3171081 prsA Anaplasma marginale str. St. Maries phosphoribosylpyrophosphate synthetase YP_154163.1 929392 D 234826 CDS YP_154164.1 56417090 3171680 930364..930684 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 930684 3171680 AM1030 Anaplasma marginale str. St. Maries hypothetical protein YP_154164.1 930364 D 234826 CDS YP_154165.2 161544982 3171805 complement(930720..933356) 1 NC_004842.2 Catalyzes the conversion of citrate to isocitrate; aconitate hydratase 933356 acnA 3171805 acnA Anaplasma marginale str. St. Maries aconitate hydratase YP_154165.2 930720 R 234826 CDS YP_154166.1 56417092 3171080 complement(933744..934196) 1 NC_004842.2 protein associated with Co2+ and Mg2+ efflux; ApaG protein 934196 apaG 3171080 apaG Anaplasma marginale str. St. Maries ApaG protein YP_154166.1 933744 R 234826 CDS YP_154167.1 56417093 3171226 934272..935342 1 NC_004842.2 COG0026 PurK phosphoribosylaminoimidazole carboxylase (NCAIR synthetase); similar to NP_830163.1; phosphoribosylaminoimidazole carboxylase 935342 purK 3171226 purK Anaplasma marginale str. St. Maries phosphoribosylaminoimidazole carboxylase YP_154167.1 934272 D 234826 CDS YP_154168.1 56417094 3171224 complement(935472..937625) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 937625 3171224 AM1037 Anaplasma marginale str. St. Maries hypothetical protein YP_154168.1 935472 R 234826 CDS YP_154169.1 56417095 3171274 938242..939717 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 939717 3171274 AM1041 Anaplasma marginale str. St. Maries hypothetical protein YP_154169.1 938242 D 234826 CDS YP_154170.1 56417096 3171418 940029..941474 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 941474 3171418 AM1046 Anaplasma marginale str. St. Maries hypothetical protein YP_154170.1 940029 D 234826 CDS YP_154171.1 56417097 3171127 complement(941505..945434) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 945434 3171127 AM1048 Anaplasma marginale str. St. Maries hypothetical protein YP_154171.1 941505 R 234826 CDS YP_154172.1 56417098 3171904 complement(945638..949768) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 949768 3171904 AM1050 Anaplasma marginale str. St. Maries hypothetical protein YP_154172.1 945638 R 234826 CDS YP_154173.1 56417099 3171870 complement(950058..955655) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210463.1; hypothetical protein 955655 3171870 AM1051 Anaplasma marginale str. St. Maries hypothetical protein YP_154173.1 950058 R 234826 CDS YP_154174.1 56417100 3171206 complement(956209..958638) 1 NC_004842.2 COG3451 VirB4 type IV secretory pathway, VirB4 components; other copies include: AM814; VirB4 protein 958638 virB4 3171206 virB4 Anaplasma marginale str. St. Maries VirB4 protein YP_154174.1 956209 R 234826 CDS YP_154175.1 56417101 3171202 complement(958771..959145) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; identity to Anaplasma (AAO41098.1) - but not the same as hypothetical protein; hypothetical protein 959145 3171202 AM1054 Anaplasma marginale str. St. Maries hypothetical protein YP_154175.1 958771 R 234826 CDS YP_154176.1 56417102 3171604 complement(959418..959795) 1 NC_004842.2 conserved hypothetical protein similar to NP_966415.1; identity to Anaplasma (AAO41098.1) but not the same as hypothetical protein; hypothetical protein 959795 3171604 AM1055 Anaplasma marginale str. St. Maries hypothetical protein YP_154176.1 959418 R 234826 CDS YP_154177.1 56417103 3171165 complement(960582..961172) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210466.1; identity to Anaplasma (AAO41095.1) but not the same as hypothetical protein; hypothetical protein 961172 3171165 AM1056 Anaplasma marginale str. St. Maries hypothetical protein YP_154177.1 960582 R 234826 CDS YP_154178.1 56417104 3171216 complement(961182..961730) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 961730 3171216 AM1057 Anaplasma marginale str. St. Maries hypothetical protein YP_154178.1 961182 R 234826 CDS YP_154179.1 56417105 3171276 961959..962324 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 962324 3171276 AM1058 Anaplasma marginale str. St. Maries hypothetical protein YP_154179.1 961959 D 234826 CDS YP_154180.1 56417106 3171349 962297..962566 1 NC_004842.2 other copies include: AM032, AM046, AM063, AM721 AM990 and AM1251; member of msp2 superfamily; hypothetical protein 962566 orfY 3171349 orfY Anaplasma marginale str. St. Maries hypothetical protein YP_154180.1 962297 D 234826 CDS YP_154181.1 56417107 3171038 962633..963028 1 NC_004842.2 other copies include: AM030, AM044, AM065, AM077 AM082, AM210, AM717, AM723, AM989, AM1149 and AM1253; member of msp2 superfamily; hypothetical protein 963028 orfX 3171038 orfX Anaplasma marginale str. St. Maries hypothetical protein YP_154181.1 962633 D 234826 CDS YP_154182.1 56417108 3171716 963365..966196 1 NC_004842.2 similar to AAN05084.1; member of msp2 superfamily; msp3 expression site; major surface protein 3 966196 msp3 3171716 msp3 Anaplasma marginale str. St. Maries major surface protein 3 YP_154182.1 963365 D 234826 CDS YP_154183.1 56417109 3171222 966443..967555 1 NC_004842.2 COG0330 HflC membrane protease subunits stomatin/prohibitin homologs; similar to NP_220514.1; other copies include: AM925; hflK protein 967555 hflK 3171222 hflK Anaplasma marginale str. St. Maries hflK protein YP_154183.1 966443 D 234826 CDS YP_154184.1 56417110 3171871 967557..968429 1 NC_004842.2 COG0330 HflC membrane protease subunits stomatin/prohibitin homologs; similar to NP_220515.1; hflC protein 968429 hflC 3171871 hflC Anaplasma marginale str. St. Maries hflC protein YP_154184.1 967557 D 234826 CDS YP_154185.1 56417111 3171075 968432..969895 1 NC_004842.2 conserved family - serine protease; hypothetical protein 969895 3171075 AM1066 Anaplasma marginale str. St. Maries hypothetical protein YP_154185.1 968432 D 234826 CDS YP_154186.1 56417112 3171248 969888..970502 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210471.1; hypothetical protein 970502 3171248 AM1067 Anaplasma marginale str. St. Maries hypothetical protein YP_154186.1 969888 D 234826 CDS YP_154187.1 56417113 3171624 970489..971187 1 NC_004842.2 cytoplasmic enzyme involved in processing rRNA and some mRNAs; substrates typically have dsRNA regions; forms a homodimer; have N-terminal nuclease and C-terminal RNA-binding domains; requires magnesium as preferred ion for activity; ribonuclease III 971187 rnc 3171624 rnc Anaplasma marginale str. St. Maries ribonuclease III YP_154187.1 970489 D 234826 CDS YP_154188.1 56417114 3171525 971218..971841 1 NC_004842.2 involved in the insertion of copper into subunit I of cytochrome C oxidase; cytochrome C oxidase assembly protein 971841 cox11 3171525 cox11 Anaplasma marginale str. St. Maries cytochrome C oxidase assembly protein YP_154188.1 971218 D 234826 CDS YP_154189.1 56417115 3171822 complement(971851..972633) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 972633 3171822 AM1073 Anaplasma marginale str. St. Maries hypothetical protein YP_154189.1 971851 R 234826 CDS YP_154190.1 56417116 3171488 complement(972972..973766) 1 NC_004842.2 similar to AAP34273.1; hypothetical protein 973766 ana29 3171488 ana29 Anaplasma marginale str. St. Maries hypothetical protein YP_154190.1 972972 R 234826 CDS YP_154191.1 56417117 3171895 973899..974120 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 974120 3171895 AM1077 Anaplasma marginale str. St. Maries hypothetical protein YP_154191.1 973899 D 234826 CDS YP_154192.1 56417118 3171277 complement(974177..975052) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 975052 3171277 AM1078 Anaplasma marginale str. St. Maries hypothetical protein YP_154192.1 974177 R 234826 CDS YP_154193.1 56417119 3170960 complement(975249..976583) 1 NC_004842.2 conserved family - protease; hypothetical protein 976583 3170960 AM1079 Anaplasma marginale str. St. Maries hypothetical protein YP_154193.1 975249 R 234826 CDS YP_154194.1 56417120 3171294 complement(976596..978017) 1 NC_004842.2 conserved family - protease; hypothetical protein 978017 3171294 AM1080 Anaplasma marginale str. St. Maries hypothetical protein YP_154194.1 976596 R 234826 CDS YP_154195.1 56417121 3170986 complement(977980..978492) 1 NC_004842.2 lipoprotein signal peptidase; integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis; lipoprotein signal peptidase 978492 lspA 3170986 lspA Anaplasma marginale str. St. Maries lipoprotein signal peptidase YP_154195.1 977980 R 234826 CDS YP_154196.1 56417122 3171451 complement(978571..979482) 1 NC_004842.2 COG0196 RibF FAD synthase; riboflavin kinase / FAD synthetase protein 979482 ribF 3171451 ribF Anaplasma marginale str. St. Maries riboflavin kinase / FAD synthetase protein YP_154196.1 978571 R 234826 CDS YP_154197.1 56417123 3171644 979550..979792 1 NC_004842.2 COG0695 GrxC glutaredoxin and related proteins; glutaredoxin 979792 grxC1 3171644 grxC1 Anaplasma marginale str. St. Maries glutaredoxin YP_154197.1 979550 D 234826 CDS YP_154198.1 56417124 3171204 complement(979944..980801) 1 NC_004842.2 COG2890 HemK predicted rRNA or tRNA methylase; protein-(glutamine-N5) methyltransferase 980801 hemK 3171204 hemK Anaplasma marginale str. St. Maries protein-(glutamine-N5) methyltransferase YP_154198.1 979944 R 234826 CDS YP_154199.1 56417125 3171219 complement(980982..981779) 1 NC_004842.2 catalyzes the removal of N-terminal amino acids from peptides and arylamides; generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn, Fe, or Mn; methionine aminopeptidase 981779 map 3171219 map Anaplasma marginale str. St. Maries methionine aminopeptidase YP_154199.1 980982 R 234826 CDS YP_154200.1 56417126 3171445 complement(981783..983096) 1 NC_004842.2 COG0508 AceF dihydrolipoamide acyltransferases; dihydrolipoamide acetyltransferase component 983096 sucB 3171445 sucB Anaplasma marginale str. St. Maries dihydrolipoamide acetyltransferase component YP_154200.1 981783 R 234826 CDS YP_154201.1 56417127 3171472 complement(983127..983516) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00053362.1; hypothetical protein 983516 3171472 AM1088 Anaplasma marginale str. St. Maries hypothetical protein YP_154201.1 983127 R 234826 CDS YP_154202.1 56417128 3171235 complement(983746..984645) 1 NC_004842.2 COG0414 PanC pantothenate synthetase; pantoate--beta-alanine ligase 984645 panC 3171235 panC Anaplasma marginale str. St. Maries pantoate--beta-alanine ligase YP_154202.1 983746 R 234826 CDS YP_154203.1 56417129 3171937 984734..985876 1 NC_004842.2 conserved family - D-alanyl-D-alanine carboxypeptidasecarboxylpeptidase; hypothetical protein 985876 3171937 AM1091 Anaplasma marginale str. St. Maries hypothetical protein YP_154203.1 984734 D 234826 CDS YP_154204.1 56417130 3171412 complement(985863..987092) 1 NC_004842.2 COG0526 TrxA thiol-disulfide isomerase and thioredoxins; cytochrome C biogenesis protein 987092 dsbD 3171412 dsbD Anaplasma marginale str. St. Maries cytochrome C biogenesis protein YP_154204.1 985863 R 234826 CDS YP_154205.1 56417131 3171131 complement(987136..987468) 1 NC_004842.2 conserved hypothetical protein similar to NP_966808.1; hypothetical protein 987468 3171131 AM1093 Anaplasma marginale str. St. Maries hypothetical protein YP_154205.1 987136 R 234826 CDS YP_154206.1 56417132 3171553 987506..988609 1 NC_004842.2 conserved family - metallopeptidase; hypothetical protein 988609 3171553 AM1094 Anaplasma marginale str. St. Maries hypothetical protein YP_154206.1 987506 D 234826 CDS YP_154207.1 56417133 3171367 988615..990954 1 NC_004842.2 COG4775 - outer membrane protein/protective antigen OMA87; similar to NP_359839.1; outer membrane protein 990954 oma87 3171367 oma87 Anaplasma marginale str. St. Maries outer membrane protein YP_154207.1 988615 D 234826 CDS YP_154208.1 56417134 3171362 990941..991501 1 NC_004842.2 conserved family - outer membrane protein; hypothetical protein 991501 3171362 AM1097 Anaplasma marginale str. St. Maries hypothetical protein YP_154208.1 990941 D 234826 CDS YP_154209.1 56417135 3171049 991507..991950 1 NC_004842.2 in Pseudomonas aeruginosa this enzyme is a trimer of dimers; essential for membrane formation; performs third step of type II fatty acid biosynthesis; catalyzes dehydration of (3R)-hydroxyacyl-ACP to trans-2-acyl-ACP; (3R)-hydroxymyristoyl-ACP dehydratase 991950 fabZ 3171049 fabZ Anaplasma marginale str. St. Maries (3R)-hydroxymyristoyl-ACP dehydratase YP_154209.1 991507 D 234826 CDS YP_154210.1 56417136 3171920 991965..993506 1 NC_004842.2 COG0138 PurH AICAR transformylase/IMP cyclohydrolase PurH; similar to NP_767221.1; phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase) 993506 purH 3171920 purH Anaplasma marginale str. St. Maries phosphoribosylaminoimidazolecarboxamide formyltransferase (AICAR transformylase) YP_154210.1 991965 D 234826 CDS YP_154211.1 56417137 3171136 complement(993515..994057) 1 NC_004842.2 COG0558 PgsA phosphatidylglycerophosphate synthase; CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase 994057 pgsA 3171136 pgsA Anaplasma marginale str. St. Maries CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase YP_154211.1 993515 R 234826 CDS YP_154212.1 56417138 3171310 994766..996070 1 NC_004842.2 conserved hypothetical protein similar to NP_220763.1; hypothetical protein 996070 3171310 AM1103 Anaplasma marginale str. St. Maries hypothetical protein YP_154212.1 994766 D 234826 CDS YP_154213.1 56417139 3171815 996098..998122 1 NC_004842.2 COG0741 MltE soluble lytic murein transglycosylase and related regulatory proteins (some); soluble lytic murein transglycosylase precursor 998122 slt 3171815 slt Anaplasma marginale str. St. Maries soluble lytic murein transglycosylase precursor YP_154213.1 996098 D 234826 CDS YP_154214.1 56417140 3171913 complement(998129..998815) 1 NC_004842.2 COG3346 - uncharacterized conserved protein; similar to NP_360750.1; surfeit locus protein 1 998815 surf1 3171913 surf1 Anaplasma marginale str. St. Maries surfeit locus protein 1 YP_154214.1 998129 R 234826 CDS YP_154215.1 56417141 3171853 999373..1001166 1 NC_004842.2 conserved hypothetical protein similar to NP_220935.1; hypothetical protein 1001166 3171853 AM1108 Anaplasma marginale str. St. Maries hypothetical protein YP_154215.1 999373 D 234826 CDS YP_154216.1 56417142 3171171 complement(1001259..1002611) 1 NC_004842.2 conserved family - dehydrogenase; hypothetical protein 1002611 3171171 AM1109 Anaplasma marginale str. St. Maries hypothetical protein YP_154216.1 1001259 R 234826 CDS YP_154217.1 56417143 3171523 1002680..1003483 1 NC_004842.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0; F0F1 ATP synthase subunit A 1003483 atpB 3171523 atpB Anaplasma marginale str. St. Maries F0F1 ATP synthase subunit A YP_154217.1 1002680 D 234826 CDS YP_154218.1 56417144 3171462 complement(1003567..1004193) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 1004193 3171462 AM1111 Anaplasma marginale str. St. Maries hypothetical protein YP_154218.1 1003567 R 234826 CDS YP_154219.2 161544981 3171687 1004848..1005072 1 NC_004842.2 Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0; F0F1 ATP synthase subunit C 1005072 atpE 3171687 atpE Anaplasma marginale str. St. Maries F0F1 ATP synthase subunit C YP_154219.2 1004848 D 234826 CDS YP_154220.1 56417146 3171855 1005079..1005579 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210501.1; hypothetical protein 1005579 3171855 AM1113 Anaplasma marginale str. St. Maries hypothetical protein YP_154220.1 1005079 D 234826 CDS YP_154221.1 56417147 3171764 1005576..1006073 1 NC_004842.2 conserved hypothetical protein similar to ZP_00210502.1; hypothetical protein 1006073 3171764 AM1114 Anaplasma marginale str. St. Maries hypothetical protein YP_154221.1 1005576 D 234826 CDS YP_154222.1 56417148 3171749 complement(1006198..1007472) 1 NC_004842.2 COG0849 FtsA predicted ATPases of the HSP70 class involved in cell division; cell division protein FtsA 1007472 ftsA 3171749 ftsA Anaplasma marginale str. St. Maries cell division protein FtsA YP_154222.1 1006198 R 234826 CDS YP_154223.1 56417149 3171587 complement(1007504..1009075) 1 NC_004842.2 COG0168 TrkG Trk-type K+ transport systems membrane components; similar to NP_791626.1; potassium uptake protein 1009075 trkH 3171587 trkH Anaplasma marginale str. St. Maries potassium uptake protein YP_154223.1 1007504 R 234826 CDS YP_154224.1 56417150 3170989 1009146..1010651 1 NC_004842.2 COG0037 MesJ predicted ATPase of the PP-loop superfamily implicated in cell cycle control; similar to NP_220436.1; cell cycle protein 1010651 mesJ 3170989 mesJ Anaplasma marginale str. St. Maries cell cycle protein YP_154224.1 1009146 D 234826 CDS YP_154225.1 56417151 3171852 1010664..1012496 1 NC_004842.2 COG0465 HflB ATP-dependent Zn proteases; cell division protein 1012496 ftsH 3171852 ftsH Anaplasma marginale str. St. Maries cell division protein YP_154225.1 1010664 D 234826 CDS YP_154226.2 161544980 3171424 1012689..1015307 1 NC_004842.2 functions in protein export; can interact with acidic membrane phospholipids and the SecYEG protein complex; binds to preproteins; binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein; ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane; additional proteins SecD/F/YajC aid SecA recycling; exists in an equilibrium between monomers and dimers; may possibly form higher order oligomers; proteins in this cluster correspond SecA1; SecA2 is not essential and seems to play a role in secretion of a subset of proteins; preprotein translocase subunit SecA 1015307 secA 3171424 secA Anaplasma marginale str. St. Maries preprotein translocase subunit SecA YP_154226.2 1012689 D 234826 CDS YP_154227.1 56417153 3171828 complement(1015158..1015364) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 1015364 3171828 AM1121 Anaplasma marginale str. St. Maries hypothetical protein YP_154227.1 1015158 R 234826 CDS YP_154228.1 56417154 3171076 complement(1015383..1016132) 1 NC_004842.2 conserved hypothetical protein similar to NP_966776.1; hypothetical protein 1016132 3171076 AM1122 Anaplasma marginale str. St. Maries hypothetical protein YP_154228.1 1015383 R 234826 CDS YP_154229.1 56417155 3171727 complement(1016136..1017089) 1 NC_004842.2 COG1230 CzcD Co/Zn/Cd efflux system component; similar to NP_692320.1; cation efflux system protein 1017089 czcD 3171727 czcD Anaplasma marginale str. St. Maries cation efflux system protein YP_154229.1 1016136 R 234826 CDS YP_154230.1 56417156 3171194 complement(1017256..1017918) 1 NC_004842.2 COG2386 CcmB ABC-type transport system involved in cytochrome C biogenesis, permease component; heme exporter protein B 1017918 ccmB 3171194 ccmB Anaplasma marginale str. St. Maries heme exporter protein B YP_154230.1 1017256 R 234826 CDS YP_154231.1 56417157 3171679 1018019..1018432 1 NC_004842.2 COG1734 DksA DnaK suppressor protein; dnaK suppressor protein 1018432 dksA 3171679 dksA Anaplasma marginale str. St. Maries dnaK suppressor protein YP_154231.1 1018019 D 234826 CDS YP_154232.1 56417158 3171175 complement(1018760..1019443) 1 NC_004842.2 COG0132 BioD dethiobiotin synthetase; dethiobiotin synthase 1019443 dtbS 3171175 dtbS Anaplasma marginale str. St. Maries dethiobiotin synthase YP_154232.1 1018760 R 234826 CDS YP_154233.1 56417159 3171258 1019519..1020436 1 NC_004842.2 COG0552 FtsY signal recognition particle GTPase; similar to NP_221126.1; cell division protein 1020436 ftsY 3171258 ftsY Anaplasma marginale str. St. Maries cell division protein YP_154233.1 1019519 D 234826 CDS YP_154234.1 56417160 3171477 1020711..1022177 1 NC_004842.2 catalyzes the formation of 2-oxoglutarate from isocitrate; isocitrate dehydrogenase 1022177 icd 3171477 icd Anaplasma marginale str. St. Maries isocitrate dehydrogenase YP_154234.1 1020711 D 234826 CDS YP_154235.1 56417161 3171567 1022302..1024062 1 NC_004842.2 COG0608 RecJ single-stranded DNA-specific exonuclease; similar to NP_220901.1; single-stranded-DNA-specific exonuclease 1024062 recJ 3171567 recJ Anaplasma marginale str. St. Maries single-stranded-DNA-specific exonuclease YP_154235.1 1022302 D 234826 CDS YP_154236.1 56417162 3171703 complement(1024037..1024336) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 1024336 3171703 AM1135 Anaplasma marginale str. St. Maries hypothetical protein YP_154236.1 1024037 R 234826 CDS YP_154237.1 56417163 3171346 1024527..1025786 1 NC_004842.2 COG0617 PcnB tRNA nucleotidyltransferase/poly(A) polymerase; similar to NP_220410.1; poly (A) polymerase 1025786 pcnB 3171346 pcnB Anaplasma marginale str. St. Maries poly (A) polymerase YP_154237.1 1024527 D 234826 CDS YP_154238.1 56417164 3170956 complement(1025923..1026363) 1 NC_004842.2 catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate; nucleoside diphosphate kinase 1026363 ndk 3170956 ndk Anaplasma marginale str. St. Maries nucleoside diphosphate kinase YP_154238.1 1025923 R 234826 CDS YP_154239.1 56417165 3171283 1026592..1027155 1 NC_004842.2 similar to AAN08687.1; hypothetical protein 1027155 3171283 AM1138 Anaplasma marginale str. St. Maries hypothetical protein YP_154239.1 1026592 D 234826 CDS YP_154240.1 56417166 3171108 1027570..1028562 1 NC_004842.2 member of msp2 superfamily; outer membrane protein 1 1028562 omp1 3171108 omp1 Anaplasma marginale str. St. Maries outer membrane protein 1 YP_154240.1 1027570 D 234826 CDS YP_154241.1 56417167 3171088 1028727..1029665 1 NC_004842.2 member of msp2 superfamily; msp2 operon associated gene 3 1029665 opag3 3171088 opag3 Anaplasma marginale str. St. Maries msp2 operon associated gene 3 YP_154241.1 1028727 D 234826 CDS YP_154242.1 56417168 3171417 complement(1028745..1029848) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; known not to be transcribed; hypothetical protein 1029848 3171417 AM1141 Anaplasma marginale str. St. Maries hypothetical protein YP_154242.1 1028745 R 234826 CDS YP_154243.1 56417169 3171683 1029680..1030591 1 NC_004842.2 member of msp2 superfamily; msp2 operon associated gene 2 1030591 opag2 3171683 opag2 Anaplasma marginale str. St. Maries msp2 operon associated gene 2 YP_154243.1 1029680 D 234826 CDS YP_154244.1 56417170 3171689 1030615..1031007 1 NC_004842.2 member of msp2 superfamily; msp2 operon associated gene 1 1031007 opag1 3171689 opag1 Anaplasma marginale str. St. Maries msp2 operon associated gene 1 YP_154244.1 1030615 D 234826 CDS YP_154245.1 56417171 3171428 1031020..1032243 1 NC_004842.2 similar to AAG31570.1; member of msp2 superfamily; major surface protein 2 1032243 msp2 3171428 msp2 Anaplasma marginale str. St. Maries major surface protein 2 YP_154245.1 1031020 D 234826 CDS YP_154246.1 56417172 3171388 complement(1032455..1032949) 1 NC_004842.2 conserved family - DnaJ domain protein; hypothetical protein 1032949 3171388 AM1145 Anaplasma marginale str. St. Maries hypothetical protein YP_154246.1 1032455 R 234826 CDS YP_154247.1 56417173 3171640 1032906..1033490 1 NC_004842.2 conserved family - nifU-like protein; hypothetical protein 1033490 3171640 AM1146 Anaplasma marginale str. St. Maries hypothetical protein YP_154247.1 1032906 D 234826 CDS YP_154248.1 56417174 3171597 complement(1034507..1034896) 1 NC_004842.2 other copies include: AM030, AM044, AM065, AM077 AM082, AM210, AM717, AM723, AM989, AM1061 and AM1253; member of msp2 superfamily; hypothetical protein 1034896 orfX 3171597 orfX Anaplasma marginale str. St. Maries hypothetical protein YP_154248.1 1034507 R 234826 CDS YP_154249.1 56417175 3171435 complement(1038392..1039126) 1 NC_004842.2 member of msp2 superfamily; outer membrane protein 2 1039126 omp2 3171435 omp2 Anaplasma marginale str. St. Maries outer membrane protein 2 YP_154249.1 1038392 R 234826 CDS YP_154250.1 56417176 3171320 complement(1039207..1039857) 1 NC_004842.2 member of msp2 superfamily; outer membrane protein 3 1039857 omp3 3171320 omp3 Anaplasma marginale str. St. Maries outer membrane protein 3 YP_154250.1 1039207 R 234826 CDS YP_154251.1 56417177 3171401 1039827..1040150 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 1040150 3171401 AM1161 Anaplasma marginale str. St. Maries hypothetical protein YP_154251.1 1039827 D 234826 CDS YP_154252.1 56417178 3171062 1040420..1041637 1 NC_004842.2 member of msp2 superfamily; outer membrane protein 4 1041637 omp4 3171062 omp4 Anaplasma marginale str. St. Maries outer membrane protein 4 YP_154252.1 1040420 D 234826 CDS YP_154253.1 56417179 3171050 1041615..1041863 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 1041863 3171050 AM1165 Anaplasma marginale str. St. Maries hypothetical protein YP_154253.1 1041615 D 234826 CDS YP_154254.1 56417180 3171054 1041982..1043100 1 NC_004842.2 member of msp2 superfamily; outer membrane protein 5 1043100 omp5 3171054 omp5 Anaplasma marginale str. St. Maries outer membrane protein 5 YP_154254.1 1041982 D 234826 CDS YP_154255.1 56417181 3171159 complement(1043468..1044283) 1 NC_004842.2 conserved hypothetical protein similar to NP_220844.1; hypothetical protein 1044283 3171159 AM1168 Anaplasma marginale str. St. Maries hypothetical protein YP_154255.1 1043468 R 234826 CDS YP_154256.1 56417182 3171403 complement(1044334..1046256) 1 NC_004842.2 COG1138 CcmF cytochrome C biogenesis factor; cytochrome C-type biogenesis protein 1046256 ccmF 3171403 ccmF Anaplasma marginale str. St. Maries cytochrome C-type biogenesis protein YP_154256.1 1044334 R 234826 CDS YP_154257.1 56417183 3171649 1046615..1049086 1 NC_004842.2 valine--tRNA ligase; ValRS; converts valine ATP and tRNA(Val) to AMP PPi and valyl-tRNA(Val); class-I aminoacyl-tRNA synthetase type 1 subfamily; has a posttransfer editing process to hydrolyze mischarged Thr-tRNA(Val) which is done by the editing domain; valyl-tRNA synthetase 1049086 valS 3171649 valS Anaplasma marginale str. St. Maries valyl-tRNA synthetase YP_154257.1 1046615 D 234826 CDS YP_154258.1 56417184 3171002 complement(1049982..1050431) 1 NC_004842.2 binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus; both the tmRNA and SmpB are regulated in cell cycle-dependent manner; functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation; SsrA-binding protein 1050431 smpB 3171002 smpB Anaplasma marginale str. St. Maries SsrA-binding protein YP_154258.1 1049982 R 234826 CDS YP_154259.1 56417185 3171126 complement(1050434..1051066) 1 NC_004842.2 COG0807 RibA GTP cyclohydrolase II; other copies include AM120 and AM1317; 3,4-dihydroxy-2-butanone 4-phosphate synthase 1051066 ribA 3171126 ribA Anaplasma marginale str. St. Maries 3,4-dihydroxy-2-butanone 4-phosphate synthase YP_154259.1 1050434 R 234826 CDS YP_154260.1 56417186 3171886 complement(1051085..1051609) 1 NC_004842.2 COG0782 GreA transcription elongation factor; transcription elongation factor greA 1051609 greA 3171886 greA Anaplasma marginale str. St. Maries transcription elongation factor greA YP_154260.1 1051085 R 234826 CDS YP_154261.1 56417187 3171366 complement(1051606..1053129) 1 NC_004842.2 produces ATP from ADP in the presence of a proton gradient across the membrane; the alpha chain is a catalytic subunit; F0F1 ATP synthase subunit alpha 1053129 atpA 3171366 atpA Anaplasma marginale str. St. Maries F0F1 ATP synthase subunit alpha YP_154261.1 1051606 R 234826 CDS YP_154262.1 56417188 3171209 complement(1053149..1053721) 1 NC_004842.2 COG0712 AtpH F0F1-type ATP synthase delta subunit (mitochondrial oligomycin sensitivity protein); ATP synthase subunit delta 1053721 atpH 3171209 atpH Anaplasma marginale str. St. Maries ATP synthase subunit delta YP_154262.1 1053149 R 234826 CDS YP_154263.1 56417189 3171006 complement(1054297..1054548) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00211180.1; hypothetical protein 1054548 3171006 AM1179 Anaplasma marginale str. St. Maries hypothetical protein YP_154263.1 1054297 R 234826 CDS YP_154264.1 56417190 3171751 complement(1054552..1055790) 1 NC_004842.2 conserved hypothetical protein similar to NP_966944.1; hypothetical protein 1055790 3171751 AM1180 Anaplasma marginale str. St. Maries hypothetical protein YP_154264.1 1054552 R 234826 CDS YP_154265.1 56417191 3171072 complement(1055787..1056539) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00211182.1; hypothetical protein 1056539 3171072 AM1181 Anaplasma marginale str. St. Maries hypothetical protein YP_154265.1 1055787 R 234826 CDS YP_154266.1 56417192 3171029 complement(1056544..1057770) 1 NC_004842.2 conserved family - ABC-transporter; hypothetical protein 1057770 3171029 AM1183 Anaplasma marginale str. St. Maries hypothetical protein YP_154266.1 1056544 R 234826 CDS YP_154267.1 56417193 3171040 1058051..1059100 1 NC_004842.2 conserved hypothetical protein similar to NP_966159.1; hypothetical protein 1059100 3171040 AM1185 Anaplasma marginale str. St. Maries hypothetical protein YP_154267.1 1058051 D 234826 CDS YP_154268.1 56417194 3171315 complement(1059095..1060324) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00211185.1; hypothetical protein 1060324 3171315 AM1186 Anaplasma marginale str. St. Maries hypothetical protein YP_154268.1 1059095 R 234826 CDS YP_154269.1 56417195 3171697 complement(1060680..1061933) 1 NC_004842.2 COG0372 GltA citrate synthase; citrate synthase 1061933 gltA 3171697 gltA Anaplasma marginale str. St. Maries citrate synthase YP_154269.1 1060680 R 234826 CDS YP_154270.1 56417196 3171301 complement(1061970..1063559) 1 NC_004842.2 contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway; GMP synthase 1063559 guaA 3171301 guaA Anaplasma marginale str. St. Maries GMP synthase YP_154270.1 1061970 R 234826 CDS YP_154271.1 56417197 3171932 complement(1063676..1063906) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 1063906 3171932 AM1189 Anaplasma marginale str. St. Maries hypothetical protein YP_154271.1 1063676 R 234826 CDS YP_154272.1 56417198 3171396 1064038..1064433 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 1064433 3171396 AM1191 Anaplasma marginale str. St. Maries hypothetical protein YP_154272.1 1064038 D 234826 CDS YP_154273.1 56417199 3171630 1065049..1066350 1 NC_004842.2 COG0508 AceF dihydrolipoamide acyltransferases; branched-chain alpha-keto acid dehydrogenase E2 subunit 1066350 pdhC 3171630 pdhC Anaplasma marginale str. St. Maries branched-chain alpha-keto acid dehydrogenase E2 subunit YP_154273.1 1065049 D 234826 CDS YP_154274.1 56417200 3171379 complement(1066507..1066761) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 1066761 3171379 AM1193 Anaplasma marginale str. St. Maries hypothetical protein YP_154274.1 1066507 R 234826 CDS YP_154275.2 161544979 3171203 1066669..1067568 1 NC_004842.2 catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; fructose-bisphosphate aldolase 1067568 fbaB 3171203 fbaB Anaplasma marginale str. St. Maries fructose-bisphosphate aldolase YP_154275.2 1066669 D 234826 CDS YP_154276.1 56417202 3171934 complement(1067822..1069627) 1 NC_004842.2 COG0768 FtsI cell division protein FtsI/penicillin-binding protein 2; penicillin-binding protein 1069627 pbpA1 3171934 pbpA1 Anaplasma marginale str. St. Maries penicillin-binding protein YP_154276.1 1067822 R 234826 CDS YP_154277.1 56417203 3171823 complement(1069608..1070543) 1 NC_004842.2 forms a complex with SecD and YajC; SecDFyajC stimulates the proton motive force-driven protein translocation; seems to modulate the cycling of SecA by stabilizing its membrane-inserted state and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; in some organisms, such as Bacillus subtilis, SecD is fused to SecF; preprotein translocase subunit SecF 1070543 secF 3171823 secF Anaplasma marginale str. St. Maries preprotein translocase subunit SecF YP_154277.1 1069608 R 234826 CDS YP_154278.1 56417204 3171223 1070689..1071069 1 NC_004842.2 conserved hypothetical protein similar to ZP_00211205.1; hypothetical protein 1071069 3171223 AM1200 Anaplasma marginale str. St. Maries hypothetical protein YP_154278.1 1070689 D 234826 CDS YP_154279.1 56417205 3171220 complement(1071072..1072304) 1 NC_004842.2 catalyzes the formation of 5-aminolevulinate from succinyl-CoA and glycine; 5-aminolevulinate synthase 1072304 hemA 3171220 hemA Anaplasma marginale str. St. Maries 5-aminolevulinate synthase YP_154279.1 1071072 R 234826 CDS YP_154280.1 56417206 3171475 complement(1072474..1073718) 1 NC_004842.2 COG0162 TyrS tyrosyl-tRNA synthetase; tyrosyl-tRNA synthetase 1073718 tyrS 3171475 tyrS Anaplasma marginale str. St. Maries tyrosyl-tRNA synthetase YP_154280.1 1072474 R 234826 CDS YP_154281.1 56417207 3171638 1074028..1075434 1 NC_004842.2 COG0174 GlnA glutamine synthase; other copies include: AM222; glutamine synthetase 1075434 glnA 3171638 glnA Anaplasma marginale str. St. Maries glutamine synthetase YP_154281.1 1074028 D 234826 CDS YP_154282.1 56417208 3171695 1075445..1076473 1 NC_004842.2 First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; phospho-N-acetylmuramoyl-pentapeptide- transferase 1076473 mraY 3171695 mraY Anaplasma marginale str. St. Maries phospho-N-acetylmuramoyl-pentapeptide- transferase YP_154282.1 1075445 D 234826 CDS YP_154283.1 56417209 3171091 1076483..1077466 1 NC_004842.2 COG0142 IspA geranylgeranyl pyrophosphate synthase; octaprenyl-diphosphate synthase 1077466 ispB 3171091 ispB Anaplasma marginale str. St. Maries octaprenyl-diphosphate synthase YP_154283.1 1076483 D 234826 CDS YP_154284.1 56417210 3171192 complement(1077541..1079622) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 1079622 3171192 AM1209 Anaplasma marginale str. St. Maries hypothetical protein YP_154284.1 1077541 R 234826 CDS YP_154285.1 56417211 3171269 complement(1079749..1080468) 1 NC_004842.2 similar to NP_220490.1; ribonucleotide transport ATP-binding protein 1080468 mkl 3171269 mkl Anaplasma marginale str. St. Maries ribonucleotide transport ATP-binding protein YP_154285.1 1079749 R 234826 CDS YP_154286.1 56417212 3171735 complement(1080473..1081252) 1 NC_004842.2 conserved family - ABC-type transport protein; hypothetical protein 1081252 3171735 AM1212 Anaplasma marginale str. St. Maries hypothetical protein YP_154286.1 1080473 R 234826 CDS YP_154287.1 56417213 3171659 complement(1081271..1082053) 1 NC_004842.2 COG0036 Rpe pentose-5-phosphate-3-epimerase; similar to EAA23792.1; ribulose-phosphate 3-epimerase 1082053 rpe 3171659 rpe Anaplasma marginale str. St. Maries ribulose-phosphate 3-epimerase YP_154287.1 1081271 R 234826 CDS YP_154288.1 56417214 3171300 complement(1082130..1084724) 1 NC_004842.2 has 3'-5' exonuclease, 5'-3' exonuclease and 5'-3'polymerase activities, primarily functions to fill gaps during DNA replication and repair; DNA polymerase I 1084724 polA 3171300 polA Anaplasma marginale str. St. Maries DNA polymerase I YP_154288.1 1082130 R 234826 CDS YP_154289.1 56417215 3171593 1085541..1085927 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 1085927 3171593 AM1216 Anaplasma marginale str. St. Maries hypothetical protein YP_154289.1 1085541 D 234826 CDS YP_154290.1 56417216 3171415 1085950..1086858 1 NC_004842.2 COG0078 ArgF ornithine carbamoyltransferase; ornithine carbamoyltransferase 1086858 argF 3171415 argF Anaplasma marginale str. St. Maries ornithine carbamoyltransferase YP_154290.1 1085950 D 234826 CDS YP_154291.1 56417217 3171185 1086868..1087983 1 NC_004842.2 Required for DNA replication; binds preferentially to single-stranded, linear DNA; recombination protein F 1087983 recF 3171185 recF Anaplasma marginale str. St. Maries recombination protein F YP_154291.1 1086868 D 234826 CDS YP_154292.1 56417218 3171766 complement(1087980..1088441) 1 NC_004842.2 member of msp2 superfamily; outer membrane protein 6 1088441 omp6 3171766 omp6 Anaplasma marginale str. St. Maries outer membrane protein 6 YP_154292.1 1087980 R 234826 CDS YP_154293.1 56417219 3171690 complement(1088481..1089671) 1 NC_004842.2 member of msp2 superfamily; outer membrane protein 7 1089671 omp7 3171690 omp7 Anaplasma marginale str. St. Maries outer membrane protein 7 YP_154293.1 1088481 R 234826 CDS YP_154294.1 56417220 3171297 complement(1089736..1090935) 1 NC_004842.2 member of msp2 superfamily; outer membrane protein 8 1090935 omp8 3171297 omp8 Anaplasma marginale str. St. Maries outer membrane protein 8 YP_154294.1 1089736 R 234826 CDS YP_154295.1 56417221 3171490 complement(1090999..1092210) 1 NC_004842.2 member of msp2 superfamily; outer membrane protein 9 1092210 omp9 3171490 omp9 Anaplasma marginale str. St. Maries outer membrane protein 9 YP_154295.1 1090999 R 234826 CDS YP_154296.1 56417222 3171576 complement(1092273..1093535) 1 NC_004842.2 member of msp2 superfamily; outer membrane protein 10 1093535 omp10 3171576 omp10 Anaplasma marginale str. St. Maries outer membrane protein 10 YP_154296.1 1092273 R 234826 CDS YP_154297.1 56417223 3171182 complement(1093976..1094518) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 1094518 3171182 AM1225 Anaplasma marginale str. St. Maries hypothetical protein YP_154297.1 1093976 R 234826 CDS YP_154298.1 56417224 3171041 1094876..1095514 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 1095514 3171041 AM1226 Anaplasma marginale str. St. Maries hypothetical protein YP_154298.1 1094876 D 234826 CDS YP_154299.1 56417225 3171588 complement(1095979..1096902) 1 NC_004842.2 conserved hypothetical protein similar to NP_966513.1; hypothetical protein 1096902 3171588 AM1228 Anaplasma marginale str. St. Maries hypothetical protein YP_154299.1 1095979 R 234826 CDS YP_154300.1 56417226 3171268 complement(1097053..1098417) 1 NC_004842.2 COG0728 MviN uncharacterized membrane protein virulence factor; similar to NP_360535.1; virulence factor MVIN 1098417 mviN 3171268 mviN Anaplasma marginale str. St. Maries virulence factor MVIN YP_154300.1 1097053 R 234826 CDS YP_154301.1 56417227 3171230 1098643..1099500 1 NC_004842.2 transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein; prolipoprotein diacylglyceryl transferase 1099500 lgt 3171230 lgt Anaplasma marginale str. St. Maries prolipoprotein diacylglyceryl transferase YP_154301.1 1098643 D 234826 CDS YP_154302.1 56417228 3171614 1099740..1099955 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 1099955 3171614 AM1232 Anaplasma marginale str. St. Maries hypothetical protein YP_154302.1 1099740 D 234826 CDS YP_154303.2 161544978 3171469 complement(1100204..1100494) 1 NC_004842.2 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase; 30S ribosomal protein S20 1100494 rpsT 3171469 rpsT Anaplasma marginale str. St. Maries 30S ribosomal protein S20 YP_154303.2 1100204 R 234826 CDS YP_154304.1 56417230 3171152 complement(1100613..1101338) 1 NC_004842.2 COG0204 PlsC 1-acyl-sn-glycerol-3-phosphate acyltransferase; similar to NP_538993.1; 1-acyl-sn-glycerol-3-phosphate acyltransferase 1101338 plsC 3171152 plsC Anaplasma marginale str. St. Maries 1-acyl-sn-glycerol-3-phosphate acyltransferase YP_154304.1 1100613 R 234826 CDS YP_154305.1 56417231 3171325 1101370..1101927 1 NC_004842.2 COG0242 Def N-formylmethionyl-tRNA deformylase; N-formylmethionylaminoacyl-tRNA deformylase 1101927 def 3171325 def Anaplasma marginale str. St. Maries N-formylmethionylaminoacyl-tRNA deformylase YP_154305.1 1101370 D 234826 CDS YP_154306.1 56417232 3170983 1102174..1103046 1 NC_004842.2 conserved hypothetical protein similar to NP_221193.1; hypothetical protein 1103046 3170983 AM1237 Anaplasma marginale str. St. Maries hypothetical protein YP_154306.1 1102174 D 234826 CDS YP_154307.1 56417233 3171646 1103188..1103916 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 1103916 3171646 AM1238 Anaplasma marginale str. St. Maries hypothetical protein YP_154307.1 1103188 D 234826 CDS YP_154308.1 56417234 3171681 complement(1104007..1104234) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 1104234 3171681 AM1239 Anaplasma marginale str. St. Maries hypothetical protein YP_154308.1 1104007 R 234826 CDS YP_154309.1 56417235 3171342 complement(1104293..1104499) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 1104499 3171342 AM1240 Anaplasma marginale str. St. Maries hypothetical protein YP_154309.1 1104293 R 234826 CDS YP_154310.1 56417236 3171117 complement(1104735..1105244) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 1105244 3171117 AM1241 Anaplasma marginale str. St. Maries hypothetical protein YP_154310.1 1104735 R 234826 CDS YP_154311.1 56417237 3171885 complement(1105289..1106398) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 1106398 3171885 AM1242 Anaplasma marginale str. St. Maries hypothetical protein YP_154311.1 1105289 R 234826 CDS YP_154312.1 56417238 3171348 complement(1106811..1108766) 1 NC_004842.2 The UvrABC repair system catalyzes the recognition and processing of DNA lesions. The beta-hairpin of the Uvr-B subunit is inserted between the strands, where it probes for the presence of a lesion; excinuclease ABC subunit B 1108766 uvrB 3171348 uvrB Anaplasma marginale str. St. Maries excinuclease ABC subunit B YP_154312.1 1106811 R 234826 CDS YP_154313.1 56417239 3171468 1108831..1110336 1 NC_004842.2 part of the preprotein secretory system; when complexed with proteins SecF and YajC, SecDFyajC stimulates the proton motive force-driven protein translocation, and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane; preprotein translocase subunit SecD 1110336 secD 3171468 secD Anaplasma marginale str. St. Maries preprotein translocase subunit SecD YP_154313.1 1108831 D 234826 CDS YP_154314.1 56417240 3171437 1110826..1112649 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 1112649 3171437 AM1248 Anaplasma marginale str. St. Maries hypothetical protein YP_154314.1 1110826 D 234826 CDS YP_154315.1 56417241 3171280 1113315..1113548 1 NC_004842.2 other copies include: AM032, AM046, AM063, AM721 AM990 and AM1059; member of msp2 superfamily; hypothetical protein 1113548 orfY 3171280 orfY Anaplasma marginale str. St. Maries hypothetical protein YP_154315.1 1113315 D 234826 CDS YP_154316.1 56417242 3171416 1113621..1114010 1 NC_004842.2 other copies include: AM030, AM044, AM065, AM077 AM082, AM210, AM717, AM723, AM989, AM1061 and AM1149; member of msp2 superfamily; hypothetical protein 1114010 orfX 3171416 orfX Anaplasma marginale str. St. Maries hypothetical protein YP_154316.1 1113621 D 234826 CDS YP_154317.1 56417243 3171911 complement(1114075..1115559) 1 NC_004842.2 conserved family - 3-octaprenyl-4-hydroxybenzoate carboxy-lyase; hypothetical protein 1115559 3171911 AM1254 Anaplasma marginale str. St. Maries hypothetical protein YP_154317.1 1114075 R 234826 CDS YP_154318.1 56417244 3171237 complement(1115669..1116658) 1 NC_004842.2 member of msp2 superfamily; outer membrane protein 11 1116658 omp11 3171237 omp11 Anaplasma marginale str. St. Maries outer membrane protein 11 YP_154318.1 1115669 R 234826 CDS YP_154319.1 56417245 3171894 complement(1116852..1117709) 1 NC_004842.2 member of msp2 superfamily; outer membrane protein 12 1117709 omp12 3171894 omp12 Anaplasma marginale str. St. Maries outer membrane protein 12 YP_154319.1 1116852 R 234826 CDS YP_154320.1 56417246 3171876 complement(1117917..1118975) 1 NC_004842.2 member of msp2 superfamily; outer membrane protein 13 1118975 omp13 3171876 omp13 Anaplasma marginale str. St. Maries outer membrane protein 13 YP_154320.1 1117917 R 234826 CDS YP_154321.1 56417247 3171446 1119261..1120514 1 NC_004842.2 GTPase; similar structure to tubulin; forms ring-shaped polymers at the site of cell division; other proteins such as FtsA, ZipA, and ZapA, interact with and regulate FtsZ function; cell division protein FtsZ 1120514 ftsZ 3171446 ftsZ Anaplasma marginale str. St. Maries cell division protein FtsZ YP_154321.1 1119261 D 234826 CDS YP_154322.1 56417248 3171818 1120891..1121355 1 NC_004842.2 conserved hypothetical protein similar to NP_966484.1; hypothetical protein 1121355 3171818 AM1264 Anaplasma marginale str. St. Maries hypothetical protein YP_154322.1 1120891 D 234826 CDS YP_154323.1 56417249 3171658 1121429..1122244 1 NC_004842.2 COG1192 Soj ATPases involved in chromosome partitioning; similar to NP_699034.1; chromosome partitioning protein 1122244 parA 3171658 parA Anaplasma marginale str. St. Maries chromosome partitioning protein YP_154323.1 1121429 D 234826 CDS YP_154324.1 56417250 3171118 1122241..1123068 1 NC_004842.2 COG1475 Spo0J predicted transcriptional regulators; similar to NP_105340.1; chromosome partitioning protein 1123068 parB 3171118 parB Anaplasma marginale str. St. Maries chromosome partitioning protein YP_154324.1 1122241 D 234826 CDS YP_154325.1 56417251 3171799 1123080..1123652 1 NC_004842.2 Essential for efficient processing of 16S rRNA; 16S rRNA-processing protein RimM 1123652 rimM 3171799 rimM Anaplasma marginale str. St. Maries 16S rRNA-processing protein RimM YP_154325.1 1123080 D 234826 CDS YP_154326.1 56417252 3171393 1123649..1124356 1 NC_004842.2 methylates guanosine-37 in various tRNAs; uses S-adenosyl-L-methionine to transfer methyl group to tRNA; tRNA (guanine-N(1)-)-methyltransferase 1124356 trmD 3171393 trmD Anaplasma marginale str. St. Maries tRNA (guanine-N(1)-)-methyltransferase YP_154326.1 1123649 D 234826 CDS YP_154327.1 56417253 3171273 1124349..1124753 1 NC_004842.2 this protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site; 50S ribosomal protein L19 1124753 rplS 3171273 rplS Anaplasma marginale str. St. Maries 50S ribosomal protein L19 YP_154327.1 1124349 D 234826 CDS YP_154328.1 56417254 3171465 complement(1124760..1125281) 1 NC_004842.2 COG1058 CinA predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA; competence / damage-inducible protein 1125281 cinA 3171465 cinA Anaplasma marginale str. St. Maries competence / damage-inducible protein YP_154328.1 1124760 R 234826 CDS YP_154329.1 56417255 3171409 1125347..1127257 1 NC_004842.2 catalyzes a two-step reaction, first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr); threonyl-tRNA synthetase 1127257 thrS 3171409 thrS Anaplasma marginale str. St. Maries threonyl-tRNA synthetase YP_154329.1 1125347 D 234826 CDS YP_154330.1 56417256 3171173 1127287..1127820 1 NC_004842.2 COG0290 InfC translation initiation factor IF3; translation initiation factor IF-3 1127820 infC 3171173 infC Anaplasma marginale str. St. Maries translation initiation factor IF-3 YP_154330.1 1127287 D 234826 CDS YP_154331.1 56417257 3170976 complement(1128227..1128682) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00142507.1; hypothetical protein 1128682 3170976 AM1275 Anaplasma marginale str. St. Maries hypothetical protein YP_154331.1 1128227 R 234826 CDS YP_154332.1 56417258 3171514 complement(1128686..1129387) 1 NC_004842.2 conserved family - integral membrane protein; hypothetical protein 1129387 3171514 AM1276 Anaplasma marginale str. St. Maries hypothetical protein YP_154332.1 1128686 R 234826 CDS YP_154333.1 56417259 3171694 complement(1129505..1130515) 1 NC_004842.2 COG0136 Asd aspartate-semialdehyde dehydrogenase; aspartate-semialdehyde dehydrogenase 1130515 asd 3171694 asd Anaplasma marginale str. St. Maries aspartate-semialdehyde dehydrogenase YP_154333.1 1129505 R 234826 CDS YP_154334.1 56417260 3171622 complement(1130517..1130825) 1 NC_004842.2 conserved hypothetical protein similar to NP_966784.1; hypothetical protein 1130825 3171622 AM1278 Anaplasma marginale str. St. Maries hypothetical protein YP_154334.1 1130517 R 234826 CDS YP_154335.1 56417261 3171860 complement(1130831..1132255) 1 NC_004842.2 COG2812 DnaX DNA polymerase III, gamma/tau subunits; DNA polymerase III subunit gamma 1132255 dnaZ 3171860 dnaZ Anaplasma marginale str. St. Maries DNA polymerase III subunit gamma YP_154335.1 1130831 R 234826 CDS YP_154336.1 56417262 3171594 complement(1132441..1133445) 1 NC_004842.2 COG0057 GapA glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase; NAD(P)-dependent glyceraldehyde 3-phosphate dehydrogenase 1133445 gapB 3171594 gapB Anaplasma marginale str. St. Maries NAD(P)-dependent glyceraldehyde 3-phosphate dehydrogenase YP_154336.1 1132441 R 234826 CDS YP_154337.1 56417263 3171565 1133834..1134778 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 1134778 3171565 AM1285 Anaplasma marginale str. St. Maries hypothetical protein YP_154337.1 1133834 D 234826 CDS YP_154338.1 56417264 3171025 1134794..1135450 1 NC_004842.2 conserved hypothetical protein similar to NP_755835.1; isoprenoid biosynthesis protein 1135450 3171025 AM1286 Anaplasma marginale str. St. Maries isoprenoid biosynthesis protein YP_154338.1 1134794 D 234826 CDS YP_154339.1 56417265 3171056 complement(1135475..1136632) 1 NC_004842.2 COG0772 FtsW bacterial cell division membrane protein; similar to NP_220792.1; cell division protein 1136632 ftsW 3171056 ftsW Anaplasma marginale str. St. Maries cell division protein YP_154339.1 1135475 R 234826 CDS YP_154340.1 56417266 3171225 complement(1136614..1137816) 1 NC_004842.2 methionine adenosyltransferase; catalyzes the formation of S-adenosylmethionine from methionine and ATP; methionine adenosyltransferase; S-adenosylmethionine synthetase 1137816 metK 3171225 metK Anaplasma marginale str. St. Maries S-adenosylmethionine synthetase YP_154340.1 1136614 R 234826 CDS YP_154341.1 56417267 3171368 1138038..1139204 1 NC_004842.2 COG0654 UbiH 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases; similar to NP_539083.1; 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase 1139204 ubiH 3171368 ubiH Anaplasma marginale str. St. Maries 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase YP_154341.1 1138038 D 234826 CDS YP_154342.1 56417268 3171512 complement(1139216..1139824) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00211261.1; hypothetical protein 1139824 3171512 AM1292 Anaplasma marginale str. St. Maries hypothetical protein YP_154342.1 1139216 R 234826 CDS YP_154343.1 56417269 3171725 1140100..1140951 1 NC_004842.2 glycine--tRNA ligase alpha chain; GlyRS; class II aminoacyl tRNA synthetase; tetramer of alpha(2)beta(2); catalyzes a two-step reaction; first charging a glycine molecule by linking its carboxyl group to the alpha-phosphate of ATP; second by transfer of the aminoacyl-adenylate to its tRNA; glycyl-tRNA synthetase subunit alpha 1140951 glyQ 3171725 glyQ Anaplasma marginale str. St. Maries glycyl-tRNA synthetase subunit alpha YP_154343.1 1140100 D 234826 CDS YP_154344.1 56417270 3171151 1140953..1143037 1 NC_004842.2 COG0751 GlyS glycyl-tRNA synthetase, beta subunit; glycyl-tRNA synthetase subunit beta 1143037 glyS 3171151 glyS Anaplasma marginale str. St. Maries glycyl-tRNA synthetase subunit beta YP_154344.1 1140953 D 234826 CDS YP_154345.1 56417271 3171214 1143119..1144258 1 NC_004842.2 chaperone Hsp40; co-chaperone with DnaK; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, dnaK-independent fashion; chaperone protein DnaJ 1144258 dnaJ 3171214 dnaJ Anaplasma marginale str. St. Maries chaperone protein DnaJ YP_154345.1 1143119 D 234826 CDS YP_154346.1 56417272 3171719 complement(1144277..1145095) 1 NC_004842.2 COG0157 NadC nicotinate-nucleotide pyrophosphorylase; nicotinate-nucleotide pyrophosphorylase 1145095 nadC 3171719 nadC Anaplasma marginale str. St. Maries nicotinate-nucleotide pyrophosphorylase YP_154346.1 1144277 R 234826 CDS YP_154347.1 56417273 3170955 1145154..1145750 1 NC_004842.2 conserved hypothetical protein similar to NP_966768.1; membrane protein 1145750 3170955 AM1298 Anaplasma marginale str. St. Maries membrane protein YP_154347.1 1145154 D 234826 CDS YP_154348.1 56417274 3171761 complement(1145742..1146239) 1 NC_004842.2 COG0817 RuvC holliday junction resolvasome endonuclease subunit; holliday (crossover) junction endodeoxyribonuclease 1146239 ruvC 3171761 ruvC Anaplasma marginale str. St. Maries holliday (crossover) junction endodeoxyribonuclease YP_154348.1 1145742 R 234826 CDS YP_154349.1 56417275 3171057 complement(1146258..1147076) 1 NC_004842.2 COG1845 CyoC heme/copper-type cytochrome/quinol oxidase subunit 3; cytochrome C oxidase subunit III 1147076 coxC 3171057 coxC Anaplasma marginale str. St. Maries cytochrome C oxidase subunit III YP_154349.1 1146258 R 234826 CDS YP_154350.1 56417276 3171819 complement(1147146..1147943) 1 NC_004842.2 COG0407 HemE uroporphyrinogen-III decarboxylase; uroporphyrinogen decarboxylase 1147943 hemE 3171819 hemE Anaplasma marginale str. St. Maries uroporphyrinogen decarboxylase YP_154350.1 1147146 R 234826 CDS YP_154351.1 56417277 3171261 1148564..1149445 1 NC_004842.2 conserved family - hemolysin; hypothetical protein 1149445 3171261 AM1303 Anaplasma marginale str. St. Maries hypothetical protein YP_154351.1 1148564 D 234826 CDS YP_154352.1 56417278 3171425 complement(1149432..1149950) 1 NC_004842.2 COG3740 - phage head maturation protease; hypothetical protein 1149950 3171425 AM1304 Anaplasma marginale str. St. Maries hypothetical protein YP_154352.1 1149432 R 234826 CDS YP_154353.2 161544977 3171502 complement(1149934..1151130) 1 NC_004842.2 hypothetical protein 1151130 3171502 AM1305 Anaplasma marginale str. St. Maries hypothetical protein YP_154353.2 1149934 R 234826 CDS YP_154354.1 56417280 3170993 1151233..1152033 1 NC_004842.2 conserved family - biotin synthesis protein; hypothetical protein 1152033 3170993 AM1306 Anaplasma marginale str. St. Maries hypothetical protein YP_154354.1 1151233 D 234826 CDS YP_154355.1 56417281 3171440 1152053..1153009 1 NC_004842.2 3 different subfamilies; catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate; quinolinate synthetase 1153009 nadA 3171440 nadA Anaplasma marginale str. St. Maries quinolinate synthetase YP_154355.1 1152053 D 234826 CDS YP_154356.1 56417282 3171436 complement(1153031..1153402) 1 NC_004842.2 COG1145 NapF ferredoxin 2; similar to NP_539195.1; ferredoxin II 1153402 fdxA 3171436 fdxA Anaplasma marginale str. St. Maries ferredoxin II YP_154356.1 1153031 R 234826 CDS YP_154357.1 56417283 3171071 1153528..1154499 1 NC_004842.2 catalyzes the formation of (R)-2,3-dihydroxy-3-methylbutanoate from (S)-2-hydroxy-2-methyl-3-oxobutanoate in valine and isoleucine biosynthesis; ketol-acid reductoisomerase 1154499 ilvC 3171071 ilvC Anaplasma marginale str. St. Maries ketol-acid reductoisomerase YP_154357.1 1153528 D 234826 CDS YP_154358.1 56417284 3171763 complement(1154526..1154783) 1 NC_004842.2 COG0290 InfC translation initiation factor IF3; translation initiation factor IF-3 1154783 infC 3171763 infC Anaplasma marginale str. St. Maries translation initiation factor IF-3 YP_154358.1 1154526 R 234826 CDS YP_154359.1 56417285 3171164 complement(1154957..1157377) 1 NC_004842.2 COG3505 VirD4 type IV secretory pathway, VirD4 components; similar to AAM00422.1; type IV secretion system protein VirB8 1157377 virD4 3171164 virD4 Anaplasma marginale str. St. Maries type IV secretion system protein VirB8 YP_154359.1 1154957 R 234826 CDS YP_154360.1 56417286 3171174 complement(1157425..1158438) 1 NC_004842.2 COG0630 VirB11 type IV secretory pathway VirB11 components, and related ATPases involved in; similar to AAM00419.1; type IV secretion system ATPase VirB11 1158438 virB11 3171174 virB11 Anaplasma marginale str. St. Maries type IV secretion system ATPase VirB11 YP_154360.1 1157425 R 234826 CDS YP_154361.1 56417287 3171939 complement(1158480..1159817) 1 NC_004842.2 COG2948 VirB10 type IV secretory pathway VirB10 components; similar to AAM00418.1; VirB10 protein 1159817 virB10 3171939 virB10 Anaplasma marginale str. St. Maries VirB10 protein YP_154361.1 1158480 R 234826 CDS YP_154362.1 56417288 3171330 complement(1159825..1160664) 1 NC_004842.2 COG3504 VirB9 type IV secretory pathway, VirB9 components; similar to AAM00421.1; VirB9 protein 1160664 virB9 3171330 virB9 Anaplasma marginale str. St. Maries VirB9 protein YP_154362.1 1159825 R 234826 CDS YP_154363.1 56417289 3171196 complement(1160651..1161340) 1 NC_004842.2 COG3736 VirB8 type IV secretion system component VirB8; VirB8 protein 1161340 virB8 3171196 virB8 Anaplasma marginale str. St. Maries VirB8 protein YP_154363.1 1160651 R 234826 CDS YP_154364.1 56417290 3171620 complement(1161459..1162592) 1 NC_004842.2 COG0807 RibA GTP cyclohydrolase II; other copies include AM120 and AM1172; GTP cyclohydrolase II 1162592 ribA 3171620 ribA Anaplasma marginale str. St. Maries GTP cyclohydrolase II YP_154364.1 1161459 R 234826 CDS YP_154365.1 56417291 3171199 complement(1162709..1163950) 1 NC_004842.2 conserved family - TPR domain protein; hypothetical protein 1163950 3171199 AM1319 Anaplasma marginale str. St. Maries hypothetical protein YP_154365.1 1162709 R 234826 CDS YP_154366.1 56417292 3171827 complement(1163892..1164419) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 1164419 3171827 AM1320 Anaplasma marginale str. St. Maries hypothetical protein YP_154366.1 1163892 R 234826 CDS YP_154367.1 56417293 3171361 complement(1164480..1165313) 1 NC_004842.2 COG0253 DapF diaminopimelate epimerase; diaminopimelate epimerase 1165313 dapF 3171361 dapF Anaplasma marginale str. St. Maries diaminopimelate epimerase YP_154367.1 1164480 R 234826 CDS YP_154368.1 56417294 3171789 complement(1165325..1166041) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 1166041 3171789 AM1324 Anaplasma marginale str. St. Maries hypothetical protein YP_154368.1 1165325 R 234826 CDS YP_154369.1 56417295 3171929 complement(1166183..1166611) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00211235.1; hypothetical protein 1166611 3171929 AM1325 Anaplasma marginale str. St. Maries hypothetical protein YP_154369.1 1166183 R 234826 CDS YP_154370.1 56417296 3171245 1167047..1168204 1 NC_004842.2 Converts 3-phospho-D-glycerate to 3-phospho-D-glyceroyl phosphate during the glycolysis pathway; phosphoglycerate kinase 1168204 pgk 3171245 pgk Anaplasma marginale str. St. Maries phosphoglycerate kinase YP_154370.1 1167047 D 234826 CDS YP_154371.1 56417297 3171575 complement(1168396..1169589) 1 NC_004842.2 COG1570 XseA exonuclease VII, large subunit; exodeoxyribonuclease large subunit 1169589 xseA 3171575 xseA Anaplasma marginale str. St. Maries exodeoxyribonuclease large subunit YP_154371.1 1168396 R 234826 CDS YP_154372.1 56417298 3171688 complement(1169564..1170232) 1 NC_004842.2 conserved hypothetical protein similar to ZP_00211231.1; hypothetical protein 1170232 3171688 AM1328 Anaplasma marginale str. St. Maries hypothetical protein YP_154372.1 1169564 R 234826 CDS YP_154373.2 161544976 3171769 1170411..1171247 1 NC_004842.2 catalyzes the formation of N-succinyl-2-amino-6-ketopimelate from succinyl-CoA and tetrahydrodipicolinate in the lysine biosynthetic pathway; 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase 1171247 dapD 3171769 dapD Anaplasma marginale str. St. Maries 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase YP_154373.2 1170411 D 234826 CDS YP_154374.1 56417300 3171089 1171248..1172579 1 NC_004842.2 in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine, which is found in the wobble position of some tRNAs and affects ribosomal frameshifting; shows potassium-dependent dimerization and GTP hydrolysis; also involved in regulation of glutamate-dependent acid resistance and activation of gadE; tRNA modification GTPase TrmE 1172579 trmE 3171089 trmE Anaplasma marginale str. St. Maries tRNA modification GTPase TrmE YP_154374.1 1171248 D 234826 CDS YP_154375.1 56417301 3171740 complement(1172736..1173293) 1 NC_004842.2 decarboxylates 4-phosphopantothenoylcysteine to form 4'-phosphopantotheine.; phosphopantothenoylcysteine decarboxylase 1173293 dfp 3171740 dfp Anaplasma marginale str. St. Maries phosphopantothenoylcysteine decarboxylase YP_154375.1 1172736 R 234826 CDS YP_154376.1 56417302 3171251 1173303..1175402 1 NC_004842.2 COG1200 RecG RecG-like helicases; similar to NP_699765.1; ATP-dependent DNA helicase 1175402 recG 3171251 recG Anaplasma marginale str. St. Maries ATP-dependent DNA helicase YP_154376.1 1173303 D 234826 CDS YP_154377.1 56417303 3171730 1175585..1176565 1 NC_004842.2 conserved family - NADH-ubiquinone oxidoreductase; hypothetical protein 1176565 3171730 AM1337 Anaplasma marginale str. St. Maries hypothetical protein YP_154377.1 1175585 D 234826 CDS YP_154378.1 56417304 3171875 complement(1176700..1178109) 1 NC_004842.2 Catalyzes first step of the de novo purine nucleotide biosynthetic pathway; amidophosphoribosyltransferase 1178109 purF 3171875 purF Anaplasma marginale str. St. Maries amidophosphoribosyltransferase YP_154378.1 1176700 R 234826 CDS YP_154379.1 56417305 3171042 complement(1178260..1178820) 1 NC_004842.2 Enables the recycling of peptidyl-tRNAs produced at termination of translation; peptidyl-tRNA hydrolase 1178820 pth 3171042 pth Anaplasma marginale str. St. Maries peptidyl-tRNA hydrolase YP_154379.1 1178260 R 234826 CDS YP_154380.1 56417306 3171385 complement(1178825..1179481) 1 NC_004842.2 the Ctc family of proteins consists of two types, one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response; 50S ribosomal protein L25/general stress protein Ctc 1179481 rplY 3171385 rplY Anaplasma marginale str. St. Maries 50S ribosomal protein L25/general stress protein Ctc YP_154380.1 1178825 R 234826 CDS YP_154381.1 56417307 3171632 complement(1179523..1179741) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 1179741 3171632 AM1341 Anaplasma marginale str. St. Maries hypothetical protein YP_154381.1 1179523 R 234826 CDS YP_154382.1 56417308 3171859 complement(1183255..1184004) 1 NC_004842.2 conserved family - competence protein F; hypothetical protein 1184004 3171859 AM1346 Anaplasma marginale str. St. Maries hypothetical protein YP_154382.1 1183255 R 234826 CDS YP_154383.1 56417309 3171795 complement(1183943..1185145) 1 NC_004842.2 dapE-encoded N-succinyl-L,L-diaminopimelic acid desuccinylase (DapE), catalyzes the hydrolysis of N-succinyl-L,Ldiaminopimelate L,L-SDAP to L,L-diaminopimelate and succinate. It is a metalloprotease containing dinuclear active sites. Its structure is similar to the carboxypeptidase G2 from Pseudomonas sp. strain RS-16 and the aminopeptidase from Aeromonas proteolytica.; succinyl-diaminopimelate desuccinylase 1185145 dapE 3171795 dapE Anaplasma marginale str. St. Maries succinyl-diaminopimelate desuccinylase YP_154383.1 1183943 R 234826 CDS YP_154384.1 56417310 3170949 complement(1185315..1187006) 1 NC_004842.2 COG0475 KefB Kef-type K+ transport systems membrane components; similar to AAL24515.1; glutathione-regulated potassium-efflux system protein 1187006 kefB 3170949 kefB Anaplasma marginale str. St. Maries glutathione-regulated potassium-efflux system protein YP_154384.1 1185315 R 234826 CDS YP_154385.1 56417311 3171698 complement(1187020..1187583) 1 NC_004842.2 conserved hypothetical protein similar to NP_966962.1; hypothetical protein 1187583 3171698 AM1349 Anaplasma marginale str. St. Maries hypothetical protein YP_154385.1 1187020 R 234826 CDS YP_154386.1 56417312 3171429 complement(1187811..1188257) 1 NC_004842.2 conserved hypothetical protein similar to NP_221229.1; hypothetical protein 1188257 3171429 AM1350 Anaplasma marginale str. St. Maries hypothetical protein YP_154386.1 1187811 R 234826 CDS YP_154387.1 56417313 3171595 complement(1188388..1189413) 1 NC_004842.2 catalyzes the oxidative decarboxylation of pyruvate with concomitant acetylation of a lipoic acid-containing dihydrolipoamide acyltransferase within the complex. The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2); it contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase; pyruvate dehydrogenase subunit beta 1189413 pdhB 3171595 pdhB Anaplasma marginale str. St. Maries pyruvate dehydrogenase subunit beta YP_154387.1 1188388 R 234826 CDS YP_154388.1 56417314 3171363 complement(1189478..1192339) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 1192339 3171363 AM1352 Anaplasma marginale str. St. Maries hypothetical protein YP_154388.1 1189478 R 234826 CDS YP_154389.1 56417315 3171360 1192852..1194273 1 NC_004842.2 COG0312 TldD predicted Zn-dependent proteases and their inactivated homologs; similar to NP_531465.1; tldD protein 1194273 tldD 3171360 tldD Anaplasma marginale str. St. Maries tldD protein YP_154389.1 1192852 D 234826 CDS YP_154390.1 56417316 3171851 complement(1194357..1194593) 1 NC_004842.2 hypothetical protein identified by Glimmer 2; hypothetical protein 1194593 3171851 AM1354 Anaplasma marginale str. St. Maries hypothetical protein YP_154390.1 1194357 R 234826 CDS YP_154391.1 56417317 3171762 complement(1194703..1195797) 1 NC_004842.2 translation-associated GTPase; the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3); fluorescence spectroscopy revealed nucleic acid binding; the yeast protein YBR025c interacts with the translation elongation factor eEF1; GTP-dependent nucleic acid-binding protein EngD 1195797 3171762 AM1355 Anaplasma marginale str. St. Maries GTP-dependent nucleic acid-binding protein EngD YP_154391.1 1194703 R 234826 CDS YP_154392.1 56417318 3171481 complement(1195978..1196568) 1 NC_004842.2 COG0245 IspF 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; similar to NP_755192.1; 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase 1196568 ispF 3171481 ispF Anaplasma marginale str. St. Maries 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase YP_154392.1 1195978 R 234826 CDS YP_154393.1 56417319 3170964 complement(1196596..1197306) 1 NC_004842.2 COG1211 IspD 4-diphosphocytidyl-2-methyl-D-erithritol synthase; similar to NP_698125.1; 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 1197306 ispD 3170964 ispD Anaplasma marginale str. St. Maries 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase YP_154393.1 1196596 R 234826 CDS